Energy metabolism in human erythrocytes: II. Effects of glucose depletion

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Abstract

Normal red cells were incubated in the absence of glucose to develop a system in which total adenosine triphosphate (ATP) turnover could be assessed. After 1 hr, the triose pool had been completely consumed. Thereafter, the metabolism of 2,3-diphosphoglycerate (DPG) to pyruvate and lactate was the sole significant source of ATP synthesis.

Authors

Stephen A. Feig, George B. Segel, Stephen B. Shohet, David G. Nathan