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William E. Shell, … , John K. Kjekshus, Burton E. Sobel
Published December 1, 1971
Citation Information: J Clin Invest. 1971;50(12):2614-2625. https://doi.org/10.1172/JCI106762.
Citation Information: J Clin Invest. 1971;50(12):2614-2625. https://doi.org/10.1172/JCI106762.
Abstract
This study was designed to develop a method for quantitative assessment of infarct size in the conscious animal based on serial changes of serum creatine phosphokinase (CPK) activity. From 11 experiments in which myocardial CPK was injected intravenously in conscious dogs, the average CPK distribution space and average CPK fractional disappearance rate from serum were found to be 11.4% of body weight and 0.48% min respectively. In other experiments, myocardial infarction was produced in 22 conscious dogs by constriction of a left coronary artery snare and serum CPK activity was determined at frequent intervals for 24 hr. Since myocardial CPK depletion reflects infarct size, infarct size was determined directly by analysis of myocardial CPK content in the same animals 24 hr after coronary artery occlusion. CPK released from the infarct was determined from observed changes in serum CPK activity analyzed according to a model taking into account the fraction of CPK released from an infarct and the rates of appearance and disappearance of CPK activity from serum. Infarct size was calculated on the basis of observed changes in serum CPK and compared to infarct size determined directly by analysis of myocardial CPK depletion. Agreement was close and results from all experiments fit the equation: [infarct size (g) determined from serum CPK] = 1.13 × [infarct size (g) determined from myocardial CPK] - 1.3, r = 0.96, n = 22. The method described is useful for accurate assessment of infarct size in the conscious animal and for detection of modification of infarct size produced by pharmacologic interventions.
Authors
William E. Shell, John K. Kjekshus, Burton E. Sobel
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Citation information
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Postinfarct risk stratification
AJ Moss, JT Bigger, CL Odoroff |
Progress in Cardiovascular Diseases | 1987 |
|
Beneficial effects of timolol on infarct size and late ventricular tachycardia in patients with acute myocardial infarction
F Roqué, LM Amuchastegui, MA Morillos, GA Mon, AL Girotti, S Drajer, M Fortunato, E Moreyra, P Tuero, JC Solchaga |
Circulation | 1987 |
|
Increased occurrence of left ventricular thrombi during early treatment with timolol in patients with acute myocardial infarction
KA Johannessen, JE Nordrehaug, G von der Lippe |
Circulation | 1987 |
|
Measurement of infarct size and percentage myocardium infarcted in a dog preparation with single photon-emission computed tomography, thallium-201, and indium 111-monoclonal antimyosin Fab
LL Johnson, KS Lerrick, J Coromilas, DW Seldin, PD Esser, JM Zimmerman, AM Keller, PO Alderson, JT Bigger, PJ Cannon |
Circulation | 1987 |
|
Quantitative relationship between left ventricular function and serum cardiac myosin light chain I levels after coronary reperfusion in patients with acute myocardial infarction
M Isobe, R Nagai, S Ueda, H Tsuchimochi, H Nakaoka, F Takaku, T Yamaguchi, K Machii, M Nobuyoshi, Y Yazaki |
Circulation | 1987 |
|
The effects of early coronary patency on the evolution of myocardial infarction: a prospective arteriographic study
AD Timmis, B Griffin, JC Crick, DJ Nelson, E Sowton |
Heart (British Cardiac Society) | 1987 |
|
Infarct size—can it be measured or modified in humans?
LM Buja, JT Willerson |
Progress in Cardiovascular Diseases | 1987 |
|
CAR ’87 Computer Assisted Radiology
HU Lemke, ML Rhodes, CC Jaffee, R Felix |
1987 | |
|
Magnetic resonance imaging (MRI) in different stages of myocardial infarction using the contrast agent gadolinium-DTPA
HW Eichstaedt, R Felix, FC Dougherty, M Langer, W Rutsch, H Schmutzler |
Clinical Cardiology | 1986 |
|
Degradation of Myocardial Structural Proteins in Myocardial Infarcted Dogs is Reduced by Ep459, a Cysteine Proteinase Inhibitor
K TSUCHIDA, H AIHARA, K ISOGAI, K HANADA, N SHIBATA |
Biological Chemistry Hoppe-Seyler | 1986 |
|
Enzymatic assessment of myocardial injury after infarction or cardiac surgery. Is isoenzyme analysis required?
WT Hermens, GM Willems, HA Davids, L Hollaar, A der Laarse |
Clinica Chimica Acta | 1986 |
|
Blood level of mitochondrial aspartate aminotransferase as an indicator of the extent of ischemic necrosis of the rat liver
T Nishimura, Y Yoshida, F Watanabe, M Koseki, T Nishida, K Tagawa, Y Kawashima |
Hepatology | 1986 |
|
Prediction of left ventricular function in acute anterior myocardial infarction by serum creatine kinase activity and precordial ECG mapping
N Marchionni, G Moschi, A Lombardi, P Tozzi, B Salani, MD BARI, L Ferrucci, M Paoletti |
Clinical Cardiology | 1986 |
|
A new approach for the enzymatic estimation of infarct size: Serum peak creatine kinase and time to peak creatine kinase activity
M Horie, H Yasue, S Omote, A Takizawa, M Nagao, S Nishida, J Kubota |
The American Journal of Cardiology | 1986 |
|
Radionuclide assessment of regional left ventricular function in acute myocardial infarction
AJ Buda, JD Dubbin, H Meindok |
American Heart Journal | 1986 |
|
Prognostic implications of regional hyperkinesia and remote asynergy of noninfarcted myocardium
W Jaarsma, CA Visser, MJ Van, JC Res, AJ Kupper, FW Verheugt, JP Roos |
The American Journal of Cardiology | 1986 |
|
Effects of early intracoronary streptokinase on infarct size estimated from cumulative enzyme release and on enzyme release rate: A randomized trial of 533 patients with acute myocardial infarction
A der Laarse, F Vermeer, WT Hermens, GM Willems, K Neef, ML Simoons, PW Serruys, J Res, FW Verheugt, XH Krauss, F Bär, C Zwaan, J Lubsen |
American Heart Journal | 1986 |
|
Infarct Size Reduction: A Review of the Clinical Trials
CA Campbell, K Przyklenk, RA Kloner |
The Journal of Clinical Pharmacology | 1986 |
|
Myocardial infarction size; effect on the training response
KK Teo, JH Horgan |
International Journal of Cardiology | 1986 |
|
A comparison of cumulated CK release with three vectorcardiographic methods of estimating myocardial infarct size
P Grøttum, JK Kjekshus |
Journal of Electrocardiology | 1986 |
|
The effect of infarct size on atrioventricular and intraventricular conduction disturbances in acute myocardial infarction
G Opolski, T Kraska, A Ostrzycki, T Zieliński, J Korewicki |
International Journal of Cardiology | 1986 |
|
Quantification of cerebral infarct size by creatine kinase BB isoenzyme
RD Bell, GM Alexander, T Nguyen, MS Albin |
Stroke; a journal of cerebral circulation | 1986 |
|
Prognostic significance of electrocardiographic site of infarction after correction for enzymatic size of infarction
ME Hands, BL Lloyd, JS Robinson, N de Klerk, PL Thompson |
Circulation | 1986 |
|
Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques
E Jucker |
1986 | |
|
Myocardial and Skeletal Muscle Bioenergetics
N Brautbar |
1986 | |
|
Acute and Chronic Heart Failure
WD Bussmann |
1986 | |
|
Creatine kinase release not associated with myocardial necrosis after short periods of coronary artery occlusion in conscious baboons
GR Heyndrickx, J Amano, T Kenna, JT Fallon, TA Patrick, WT Manders, GG Rogers, C Rosendorff, SF Vatner |
Journal of the American College of Cardiology | 1985 |
|
Myocardial infarct size and mortality in diabetic patients
DJ Gwilt, M Petri, PW Lewis, M Nattrass, BL Pentecost |
British heart journal | 1985 |
|
Kinetics of serum creatine kinase and creatine kinase-MB after intracoronary thrombolysis
FM Bartelsen, W Rehpenning, K Harm, M Runge, DG Mathey |
Klinische Wochenschrift | 1985 |
|
Ischemia during angioplasty after streptokinase: A marker of myocardial salvage
LF Satler, CE Rackley, CE Green, RS Pallas, DL Pearle, AA Negro, KM Kent |
The American Journal of Cardiology | 1985 |
|
Course of chest pain and its relation to CK release and vector changes in patients with acute myocardial infarction randomized to treatment with intravenous timolol or placebo
M Sederholm, P Grøttum, J Kjekshus, L Erhardt |
American Heart Journal | 1985 |
|
Late estimation of myocardial infarct size by total creatine kinase nomogram
T Shibata, H Hashimoto, T Ito, K Ogawa, T Satake, H Sassa |
American Heart Journal | 1985 |
|
Early detection of myocardial infarction in conscious dogs by analysis of plasma MM creatine kinase isoforms
H Hashimoto, DR Abendschein, AW Strauss, BE Sobel |
Circulation | 1985 |
|
Adverse effects of chronic cardiac denervation in conscious dogs with myocardial ischemia
M Lavallee, J Amano, SF Vatner, WT Manders, WC Randall, JX Thomas |
Circulation research | 1985 |
|
Quantification of myocardial infarction: a comparison of single photon-emission computed tomography with pyrophosphate to serial plasma MB-creatine kinase measurements
DE Jansen, JR Corbett, CL Wolfe, SE Lewis, G Gabliani, N Filipchuk, G Redish, RW Parkey, LM Buja, AS Jaffe |
Circulation | 1985 |
|
The Ventricle
HJ Levine, WH Gaasch |
1985 | |
|
Acute Coronary Care 1986
RM Califf, GS Wagner |
1985 | |
|
Diagnosis and Therapy of Coronary Artery Disease
PF Cohn |
1985 | |
|
Clinical Pharmacology of Antianginal Drugs
U Abshagen |
1985 | |
|
Kinetics of serum creatine kinase and creatine kinase-MB after intracoronary thrombolysis
, W Rehpenning, K Harm, M Runge, DG Mathey |
Klinische Wochenschrift | 1985 |
|
Quantification of ischemic stress during repeated coronary artery occlusion in the dog A method for validation of therapeutic effects
H Korb, A Hoeft, D Baller, HG Wolpers, G Hellige, HJ Bretschneider |
Basic Research in Cardiology | 1984 |
|
Patterns of Creatine Kinase Release During Acute Myocardial Infarction After Nonsurgical Reperfusion: Comparison With Conventional Treatment and Correlation With Infarct Size
H Blanke, D Hardenberg, M Cohen, H Kaiser, KR Karsch, J Holt, H Smith, P Rentrop |
Journal of the American College of Cardiology | 1984 |
|
Emission computed tomography with technetium-99m pyrophosphate for delineating location and size of acute myocardial infarction in man
S Tamaki, K Kadota, H Kambara, Y Suzuki, R Nohara, T Murakami, C Kawai, N Tamaki, K Torizuka |
British heart journal | 1984 |
|
Systemic Short-Term Fibrinolysis with High-Dose Streptokinase in Acute Myocardial Infarction: Time Course of Biochemical Parameters
SW Golf, H Temme, KD Kempf, H Bleyl, A Brüstle, R Bödeker, D Heinrich |
Clinical Chemistry and Laboratory Medicine | 1984 |
|
Time lapse from estimated onset of acute myocardial infarction to peak serum enzyme activity
J Herlitz, Å Hjalmarson, J Waldenströ |
Clinical Cardiology | 1984 |
|
Size estimation of acute myocardial infarction from serial serum myoglobin observations with due consideration of individual differences in basic kinetics
T Groth, M Hakman, C Sylvén |
Scandinavian Journal of Clinical & Laboratory Investigation | 1984 |
|
Relation between enzyme release and metabolic changes in reversible anoxic injury of myocardial cells
HM Piper, JF Hütter, PG Spieckermann |
Life Sciences | 1984 |
|
Relationship between the Enzymatically Estimated Infarct Size and Clinical Findings in Acute Myocardial Infarction
J Herlitz, J Waldenström, Å Hjalmarson |
Acta Medica Scandinavica | 1984 |
|
II Study Design, Patient Characteristics and Conduct of the Study
HJ Jürgensen, MP Andersen, P Bechsgaard, J Frederiksen, DA Hansen, PB Nielsen, F Pedersen, O Pedersen-Bjergaard, SL Rasmussen |
Acta Medica Scandinavica | 1984 |
|
IV Salvage of Ischaemic Myocardium by Alprenolol
HJ Jürgensen, J Frederiksen, DA Hansen, O Pedersen-Bjergaard |
Acta Medica Scandinavica | 1984 |
|
Quantification of myonecrosis and comparison of necrotic activity of snake venoms by determination of creatine phosphokinase activity in mice sera
K Nakada, F Nakada, E Ito, F Inoue |
Toxicon | 1984 |
|
Reduction of creatine kinase and creatine kinase-MB indexes of infarct size by intravenous verapamil
WD Bussmann, W Seher, M Gruengras |
The American Journal of Cardiology | 1984 |
|
Early intervention in acute myocardial infarction: One center's perspective
BE Sobel |
The American Journal of Cardiology | 1984 |
|
Imaging of acute myocardial infarction in man with contrast-enhanced computed transmission tomography
PH Kramer, JA Goldstein, RJ Herkens, MJ Lipton, BH Brundage |
American Heart Journal | 1984 |
|
Diagnosis of acute myocardial infarction by detection of circulating cardiac myosin light chains
HA Katus, T Yasuda, HK Gold, RC Leinbach, HW Strauss, C Waksmonski, E Haber, BA Khaw |
The American Journal of Cardiology | 1984 |
|
Measurement of infarct size in acute canine myocardial infarction by single-photon emission computed tomography with technetium-99m pyrophosphate
SE Lewis, MD Devous, JR Corbett, C Izquierdo, P Nicod, CL Wolfe, RW Parkey, LM Buja, JT Willerson |
The American Journal of Cardiology | 1984 |
|
Effects of steroid treatment on release of cardiac myosin light chain II in acute myocardial infarction in dogs
R Nagai, M Isobe, CC Chiu, K Yamaoki, Y Ohuchi, S Ueda, K Imataka, Y Yazaki |
The American Journal of Cardiology | 1984 |
|
Measurement of myocardial infarct size by technetium pyrophosphate single-photon tomography
JR Corbett, SE Lewis, CL Wolfe, DE Jansen, M Lewis, JS Rellas, RW Parkey, RE Rude, LM Buja, JT Willerson |
The American Journal of Cardiology | 1984 |
|
Assessment of myocardial damage in patients with acute myocardial infarction by serial measurement of serum α-hydroxybutyrate dehydrogenase levels
A der Laarse, WT Hermens, L Hollaar, M Jol, GM Willems, HE Lemmers, AH Liem, JH Souverijn, JH Oudhof, J Hooge, B Buis, AC Arntzenius |
American Heart Journal | 1984 |
|
Relationship between electrocardiographically and enzymatically estimated size in anterior myocardial infarction
J Herlitz, A Hjalmarson, J Waldenström |
Journal of Electrocardiology | 1984 |
|
Effect of Propranolol on Myocardial-Infarct Size in a Randomized Blinded Multicenter Trial
R Roberts, C Croft, HK Gold, TD Hartwell, AS Jaffe, JE Muller, SM Mullin, C Parker, ER Passamani, WK Poole, DS Raabe, RE Rude, PH Stone, ZG Turi, BE Sobel, JT Willerson, E Braunwald |
New England Journal of Medicine | 1984 |
|
Relationship between electrocardiographically estimated infarct size and clinical findings in inferior myocardial infarction: Infarct size and clinical findings in inferior MI
J Herlitz, Å Hjalmarson |
Clinical Cardiology | 1984 |
|
Relationship between electrocardiographically estimated infarct size and clinical findings in anterior myocardial infarction
J Herlitz, Å HJALMARSON |
Clinical Cardiology | 1984 |
|
Infarct Size as a Determinant of Acute and Long-Term Prognosis
EM Geltman |
Cardiology Clinics | 1984 |
|
Evolution of infarct size during the early use of nifedipine in patients with acute myocardial infarction: the Norwegian Nifedipine Multicenter Trial
PA Sirnes, K Overskeid, TR Pedersen, J Bathen, A Drivenes, GS Frøland, JK Kjekshus, K Landmark, R Rokseth, KE Sirnes |
Circulation | 1984 |
|
Comparison of enzymatic and anatomic estimates of myocardial infarct size in man
DB Hackel, KA Reimer, RE Ideker, EM Mikat, TD Hartwell, CB Parker, EB Braunwald, M Buja, HK Gold, AS Jaffe |
Circulation | 1984 |
|
Koronarerkrankungen
H Roskamm, E Bassenge, HJ Becker, G Breithardt, P Bubenheimer, L Buchholz, CD Claussen, C Droste, H Eichstädt, WA Fach, R Felix, A Frey, L Görnandt, H Gohlke, C Gohlke-Bärwolf, M Gottwik, AR Gruentzig, P Harnasch, K Huesmann, T Ischinger, M Kaltenbach, D Kalusche, M Keck, D Köhler, W Langosch, G Lohmöller, H Lydtin, BV Mai, DG Mathey, W Morgenstern, E Nüssel, O Pachinger, J Petersen, R Poche, H Reindell, B Ritter, L Samek, W Schaper, R Scheidt, M Schmuziger, W Schneider, K Schnellbacher, KP Schüren, L Seipel, M Siebes, H Sochor, E Steinmann, M Stolte, P Stürzenhofecker, P Tollenaere, H Weidemann, A Weisswange, B Wille |
1984 | |
|
Acute Coronary Care
RM Califf, GS Wagner |
1984 | |
|
Effect of intraoperative propranolol on serum creatine kinase MB release in patients having elective cardiac operations
PS Rao, FE Brock, K Cleary, H Mueller, HB Barner |
The Journal of Thoracic and Cardiovascular Surgery | 1984 |
|
Quantification of ischemic stress during repeated coronary artery occlusion in the dog A method for validation of therapeutic effects: II. Reproducibility of the release and uptake of electrolytes and substrates
H Korb, A Hoeft, D Baller, HG Wolpers, G Hellige, HJ Bretschneider |
Basic Research in Cardiology | 1984 |
|
Anterior transmural myocardial infarction: Effects of surgical coronary reperfusion on global and regional left ventricular function
MA DeWood, J Heit, J Spores, R Berg, SL Selinger, LW Rudy, GR Hensley, JP Shields |
Journal of the American College of Cardiology | 1983 |
|
Effects of coronary artery reperfusion on relation between creatine kinase-MB release and infarct size estimated by myocardial emission tomography with thallium-201 in man
S Tamaki, T Murakami, K Kadota, H Kambara, Y Yui, H Nakajima, Y Suzuki, R Nohara, Y Takatsu, C Kawai, N Tamaki, T Mukai, K Torizuka |
Journal of the American College of Cardiology | 1983 |
|
Comparison of radionuclide and enzymatic estimate of infarct size in patients with acute myocardial infarction
GS Hirsowitz, JB Lakier, DS Marks, TG Lee, AD Goldberg, S Goldstein |
Journal of the American College of Cardiology | 1983 |
|
Clinical Evaluation of Models and Markers of Myocardial Ischemia
M Hørder, PH Petersen, K Thygesen |
Upsala Journal of Medical Sciences | 1983 |
|
Limitation of enzymatic models for predicting myocardial infarct size
K Thygesen, M Hørder, PH Petersen, BL Nielsen |
British heart journal | 1983 |
|
Infarct size estimation from serial CK MB determinations: peak activity and predictability
JW Fiolet, HF Welle, FJ van Capelle, KI Lie |
British heart journal | 1983 |
|
Patterns of cellular injury in myocardial ischemia determined by monoclonal antimyosin
AC Nolan, WA Clark, T Karwoski, R Zak |
Proceedings of the National Academy of Sciences | 1983 |
|
Comparison of ASTK, CK, CK-MB, and LD for the estimation of acute myocardial infarct size in man
P Grande, C Christiansen, K Alstrup |
Clinica Chimica Acta | 1983 |
|
Pranolium
GA Kopia, BT Eller, E Patterson, BR Lucchesi |
Cardiovascular Drug Reviews | 1983 |
|
Late prognostic value of scintigraphic parameters of acute myocardial infarction size in complicated myocardial infarction without heart failure
EH Botvinick, JF Perez-Gonzalez, R Dunn, T Ports, K Chatterjee, W Parmley |
The American Journal of Cardiology | 1983 |
|
Evaluation of a QRS scoring system in acute myocardial infarction: Relation to infarct size, early stage left ventricular ejection fraction, and exercise performance
Y Seino, HM Staniloff, WE Shell, D Mickle, PK Shah, JK Vyden |
The American Journal of Cardiology | 1983 |
|
Effects of nonsurgical myocardial reperfusion on plasma creatine kinase kinetics in man
W Shell, DK Mickle, HJ Swan |
American Heart Journal | 1983 |
|
Myocardial infarct extension: Prevalence, clinical significance, and problems in diagnosis
AJ Buda, IL Macdonald, JD Dubbin, SA Orr, HD Strauss |
American Heart Journal | 1983 |
|
Direct determination of distribution volume and disappearance rate of native creatine kinase in humans
G Tommasini, RP Karlsberg, F Tamagni, R Berra, A Oddone, M Orlandi, W Raimondi, R Malusardi |
American Heart Journal | 1983 |
|
Myocardial Infarction and Cardiac Death
WH Frishman, EH Sonnenblick |
Myocardial Infarction and Cardiac Death | 1983 |
|
A mathematical model for estimation of infarct size from serum creatine phosphokinase
FH Schmidt |
Computers and Biomedical Research | 1983 |
|
Serum myoglobin concentration as an index of myocardial damage after cardiac surgery
RN Johnson, JM Neutze, AR Kerr, B Gillain |
International Journal of Cardiology | 1983 |
|
Serum Angiotensin-Converting Enzyme
MA Hollinger |
Chest | 1983 |
|
The effects of cyanide and iodoacetate intoxication and ischaemia on enzyme release from the perfused rat heart
TJ Higgins, PJ Bailey |
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 1983 |
|
Quantitative assessment of myocardial ischemia and necrosis by continuous vectorcardiography and measurement of creatine kinase release in patients
M Sederholm, P Grøttum, L Erhardt, J Kjekshus |
Circulation | 1983 |
|
A randomized prospective trial of intravenous nitroglycerin in patients with acute myocardial infarction
JT Flaherty, LC Becker, BH Bulkley, JL Weiss, G Gerstenblith, CH Kallman, KJ Silverman, JY Wei, B Pitt, ML Weisfeldt |
Circulation | 1983 |
|
Persistent reduction in left ventricular asynergy in patients with acute myocardial infarction by intravenous infusion of nitroglycerin
BI Jugdutt, BA Sussex, JW Warnica, RE Rossall |
Circulation | 1983 |
|
Methods for Diagnosis, Estimation and Prediction of Myocardial Damage from Serum Observations of Marker Substances
TL Groth |
Upsala Journal of Medical Sciences | 1983 |
|
Correlation between enzymatic estimation of infarct size and early mortality rate
J Herlitz, A Hjalmarson, J Waldenstrom, K Swedberg, F Waagstein, A Waldenstrom |
Heart (British Cardiac Society) | 1983 |
|
Diagnostic criteria and prognosis of perioperative myocardial infarction following coronary bypass
PG Val, LC Pelletier, MG Hernandez, JM Jais, BR Chaitman, G Dupras, BC Solymoss |
The Journal of Thoracic and Cardiovascular Surgery | 1983 |
|
Intracoronary thrombolysis in acute myocardial infarction: Correlations among serum enzyme, scintigraphic and hemodynamic findings
F Schwarz, G Schuler, H Katus, HC Mehmel, K Olshausen, M Hofmann, HJ Herrmann, W Kübler |
The American Journal of Cardiology | 1982 |
|
Detection of Myocardial Injury after Coronary Artery Bypass Grafting Using a Hypothermic, Cardioplegic Technique
HG McDaniel, JG Reves, NT Kouchoukos, LR Smith, WJ Rogers, PN Samuelson, WA Lell |
The Annals of Thoracic Surgery | 1982 |
|
Improved procedures for purification of human and canine creatine kinase isoenzymes
A Grace, R Roberts |
Clinica Chimica Acta | 1982 |
|
Macroscopic and microscopic measurement of myocardial infarct size
N Banka, IS Anand, OP Nirankari, S Gulati, PL Sharma, RN Chakravarti, PL Wahi |
Research in Experimental Medicine | 1982 |
|
EFFECTS OF EARLY ADMINISTRATION OF A HIGHLY PURIFIED HYALURONIDASE PREPARATION (GL ENZYME) ON MYOCARDIAL INFARCT SIZE
S Saltissi, DJ Coltart, PS Robinson, MM Webb-Peploe, DN Croft |
The Lancet | 1982 |
|
Quantitation of myonecrosis induced by myotoxin a from prairie rattlesnake (Crotalus viridis viridis) venom
CL Ownby, JM Gutiérrez, TR Colberg, GV Odell |
Toxicon | 1982 |
|
Cardiac enzymes
CC Johnston, EC Bolton |
Annals of Emergency Medicine | 1982 |
|
Measurement of infarct size using single photon emission computed tomography and technetium-99m pyrophosphate: A description of the method and comparison with patient prognosis
BL Holman, SZ Goldhaber, CM Kirsch, JF Polak, BJ Friedman, RJ English, J Wynne |
The American Journal of Cardiology | 1982 |
|
Spontaneous changes in thallium-201 myocardial perfusion imaging after myocardial infarction
AJ Buda, JD Dubbin, IL Macdonald, HD Strauss, SA Orr, H Meindok |
The American Journal of Cardiology | 1982 |
|
Effect of Short-Term Infusion of Sodium Nitroprusside on Mortality Rate in Acute Myocardial Infarction Complicated by Left Ventricular Failure: Results of a Veterans Administration Cooperative Study
JN Cohn, JA Franciosa, GS Francis, D Archibald, F Tristani, R Fletcher, A Montero, G Cintron, J Clarke, D Hager, R Saunders, F Cobb, R Smith, H Loeb, H Settle |
New England Journal of Medicine | 1982 |
|
Creatine Kinase
R Bais, JB Edwards |
Critical Reviews in Clinical Laboratory Sciences | 1982 |
|
Intravenous hyaluronidase therapy for myocardial infarction in man: double-blind trial to assess infarct size limitation
JA Cairns, DA Holder, P Tanser, E Missirlis |
Circulation | 1982 |
|
Estimation of infarct size by myocardial emission computed tomography with thallium-201 and its relation to creatine kinase-MB release after myocardial infarction in man
S Tamaki, H Nakajima, T Murakami, Y Yui, H Kambara, K Kadota, A Yoshida, C Kawai, N Tamaki, T Mukai, Y Ishii, K Torizuka |
Circulation | 1982 |
|
Effect of infarct location on the in-hospital prognosis of patients with first transmural myocardial infarction
S Thanavaro, RE Kleiger, MA Province, JW Hubert, JP Miller, RJ Krone, GC Oliver |
Circulation | 1982 |
|
The late prognostic value of acute scintigraphic measurement of myocardial infarction size
J Perez-Gonzalez, EH Botvinick, R Dunn, S Rahimtoola, T Ports, K Chatterjee, WW Parmley |
Circulation | 1982 |
|
Estimation of acute myocardial infarct size in man by serum CK-MB measurements
P Grande, BF Hansen, C Christiansen, J Naestoft |
Circulation | 1982 |
|
Atherosclerosis Clinical Evaluation and Therapy
S Lenzi, GC Descovich |
1982 | |
|
Transluminal Coronary Angioplasty and Intracoronary Thrombolysis
M Kaltenbach, AR Grüntzig, KP Rentrop, WD Bussmann |
1982 | |
|
Myocardial Injury: Quantitation by Cell Sorting Initiated with Antimyosin Fluorescent Spheres
BA Khaw, J Scott, JT Fallon, SL Cahill, E Haber, C Homcy |
Science | 1982 |
|
Release of angiotensin converting enzyme by the lung after Pseudomonas bacteremia in sheep
AB Gorin, G Hasagawa, M Hollinger, J Sperry, J Zuckerman |
Journal of Clinical Investigation | 1981 |
|
Cultured neonate rat myocytes as a model for the study of myocardial ischaemic necrosis
TJ Higgins, PJ Bailey, D Allsopp, DA Imhof |
Journal of Pharmacy and Pharmacology | 1981 |
|
Limitation of myocardial infarct size in patients less than 66 years treated with alprenolol
JH Jürgensen, J Frederiksen, DA Hansen, O Pedersen-Bjergaard |
British heart journal | 1981 |
|
Advantages of technetium pyrophosphate scintigraphy over plasma enzyme analysis in estimation of anterior myocardial infarct size
S Saltissi, PS Robinson, MM Webb-Peploe, DJ Coltart, DN Croft |
British heart journal | 1981 |
|
Radioimmunoassay of inactive creatine kinase B protein in human plasma
MH Burnam, WE Shell |
Clinica Chimica Acta | 1981 |
|
PISA: A noninvasive method in detection and quantification of acid-induced myocardial infarction in dogs
K Prasad, MM Gupta |
Clinical Cardiology | 1981 |
|
A two-site immunoradiometric assay for the MB isoenzyme of creatine kinase
VJ Willson, HM Jones, RJ Thompson |
Clinica Chimica Acta | 1981 |
|
HISTOLOGIC MAPPING OF INFARCTED MYOCARDIUM A New Method for Evaluation of Myocardial Infarct in Autopsy Cases
P Shin, S Onishi, T Minamino, H Kitamura |
Pathology International | 1981 |
|
ENZYME ANALYSIS IN A MULTICENTRE TRIAL ON STREPTOKINASE TREATMENT IN ACUTE MYOCARDIAL INFARCTION
WT Hermens |
Acta Medica Scandinavica | 1981 |
|
Acute myocardial infarct size estimated by serum CK-MB determinations: Clinical accuracy and prognostic relevance utilizing a practical modification of the isoenzyme approach
P Grande, BF Hansen, C Christiansen, J Næstoft |
American Heart Journal | 1981 |
|
Histologic, ultrastructural, and enzymatic measurements of infarct size following coronary artery stenosis and occlusion
FC White, PJ Russell, M Ashraf, P Wolf, L Higginson, D Jones, CM Bloor |
American Heart Journal | 1981 |
|
Early appearance of MB-creatine kinase activity in nontransmural myocardial infarction detected by a sensitive assay for the isoenzyme
WE Shell, MA DeWood, M Kligerman, W Ganz, HJ Swan |
The American Journal of Medicine | 1981 |
|
Cardiac Pharmacology
JM Downey, DF Munch |
Cardiac Pharmacology | 1981 |
|
Intravenous Propranolol Therapy for Acute Myocardial Infarction in Man
JA Cairns, GA Klassen |
Chest | 1981 |
|
Lactic Dehydrogenase and Fraction 1 in Acute Myocardial Infarction
RB Whiting |
Angiology | 1981 |
|
Detection of residual myocardial function in acute transmural infarction using postextrasystolic potentiation. A computerized angiographic study
I Azancot, P Beaufils, C Masquet, G Georgiopoulos, D Babalis, P Lorente, Y Baudouy, R Slama, Y Bouvrain |
Circulation | 1981 |
|
Reduction of CK and CK-MB indexes of infarct size by intravenous nitroglycerin
WD Bussmann, D Passek, W Seidel, M Kaltenbach |
Circulation | 1981 |
|
Effects of coronary artery reperfusion on myocardial infarct size and survival in conscious dogs
KL Baughman, PR Maroko, SF Vatner |
Circulation | 1981 |
|
The effect of intravenous nitroglycerin on coronary blood flow and infarct size during myocardial infarction in conscious dogs
T Fukuyama, R Roberts |
Clinical Cardiology | 1980 |
|
Comparison of enzymic with cineangiocardiographic estimations of myocardial infarct size
NL Sammel, JG Stuckey, PW Brandt, RM Norris |
British heart journal | 1980 |
|
Creatine kinase and its isoenzymes in dog sera
M Knob, I Seidl |
Clinica Chimica Acta | 1980 |
|
MB Creatine Kinase and the Evaluation of Myocardial Injury Following Aortocoronary Bypass Operation
C Cailar, JG Maillé, W Jones, BC Solymoss, M Chabot, C Goulet, E Delva, CM Grondin |
The Annals of Thoracic Surgery | 1980 |
|
Radioimmunoassay for Dog Myoglobin
AC Vanderbroucke, JA Cairns, E Missirlis, J Gauldie |
Journal of Immunoassay | 1980 |
|
Cause and course of acute myocardial infarction
JT Willerson, LM Buja |
The American Journal of Medicine | 1980 |
|
Prevention of cardiogenic shock
JS Geddes, AA Adgey, JF Pantridge |
American Heart Journal | 1980 |
|
Lidocaine-induced reduction in size of experimental myocardial infarction
JD Dewey, FN Nasser, JT Walls, WD Edwards, CE Harrison |
The American Journal of Cardiology | 1980 |
|
Effect of arterial pressure on left ventricular O2 consumption, coronary blood flow, and reserve capacity following coronary occlusion
WJ Bugni, AC Kralios, TJ Tsagaris, H Kuida |
American Heart Journal | 1980 |
|
Ion-exchange chromatography of creatine kinase isoenzymes: A method with improved specificity and sensitivity
WH Bailey |
Biochemical Medicine | 1980 |
|
Interactive Coupling of a TRS-80 Microcomputer to a Nova II-Based Coronary Care Monitoring System
J Sorkin, J Sampson, G Kelen, D Bloomfield |
Proceedings of the Annual Symposium on Computer Application in Medical Care | 1980 |
|
Dobutamine vs Furosemide in the Treatment of Cardiac Failure due to Right Ventricular Infarction
G Clark, HD Strauss, R Roberts |
Chest | 1980 |
|
Effect of the Kallikrein Inhibitor Aprotinin on Myocardial Ischemia and Necrosis in Man
FA Ceceña-Seldner, J Villarreal |
Angiology | 1980 |
|
Corticosteroids in Acute Myocardial Infarction
CA Bush, W Renner, H Boudoulas |
Angiology | 1980 |
|
Digitalis and myocardial infarction in man
J Morrison, J Coromilas, M Robbins, L Ong, S Eisenberg, R Stechel, M Zema, P Reiser, L Scherr |
Circulation | 1980 |
|
Nonlinear relationship between creatine kinase estimates and histologic extent of infarction in conscious dogs: effects of regional myocardial blood flow
JL Swain, FR Cobb, PA McHale, CR Roe |
Circulation | 1980 |
|
In-hospital prognosis of patients with first nontransmural and transmural infarctions
S Thanavaro, RJ Krone, RE Kleiger, MA Province, JP Miller, VR deMello, GC Oliver |
Circulation | 1980 |
|
Correlation of radionuclide estimates of myocardial infarction size and release of creatine kinase-MB in man
J Morrison, J Coromilas, D Munsey, M Robbins, M Zema, SU Chiaramida, P Reiser, L Scherr |
Circulation | 1980 |
|
QRS mapping in the evaluation of acute anterior myocardial infarction
R von Essen, W Merx, R Doerr, S Effert, J Silny, G Rau |
Circulation | 1980 |
|
Verhandlungen der Deutschen Gesellschaft für innere Medizin
B Schlegel |
1980 | |
|
Clinical Estimation of Infarct Size by 201 Thallium Perfusion Scintigraphy and by Creatine Kinase-MB in Early Myocardial Infarction
JW Fletcher, PS Rao, KF Witztum, WP Hamilton, RM Donati, HS Mueller |
Clinical Cardiology | 1980 |
|
Myocardial Infarct Imaging of Antibodies to Canine Cardiac Myosin with Indium-111-Diethylenetriamine Pentaacetic Acid
BA Khaw, JT Fallon, HW Strauss, E Haber |
Science | 1980 |
|
Creatine Kinase Release, Potassium-42 Content, and Mechanical Performance in Anoxic Rabbit Myocardium
GL Conrad, EE Rau, KI Shine |
Journal of Clinical Investigation | 1979 |
|
The effects of oral sucrose and of estimated infarct size on plasma free fatty acids, plasma glucose and serum insulin in the early stages of acute myocardial infarction
MJ Tansey, LH Opie, BM Kennelly |
European Journal of Clinical Investigation | 1979 |
|
Electrocardiographic mapping of ischaemic myocardial insult
JK Kjekshus |
Acta Medica Scandinavica | 1979 |
|
Limitation of Myocardial Infarct Size: Review of Experimental Basis and Clinical Trials
PL Thompson |
Australian and New Zealand Journal of Medicine | 1979 |
|
PRediction of infarct size by enzymatic techniques: modification of a method and clinical application
G Tommasini, M Presta |
British heart journal | 1979 |
|
Correlation of ejection fraction and infarct size estimated from the total CK released in patients with acute myocardial infarction
M Hori, M Inoue, S Fukui, T Shimazu, M Mishima, N Ohgitani, T Minamino, H Abe |
British heart journal | 1979 |
|
Prediction of infarct size from serial CK determinations: Evaluation by clinical studies and computer simulation
SA Danner, EM Smit, GA Hart, H Oosting, AJ Dunning |
Clinica Chimica Acta | 1979 |
|
Experimental coronary artery occlusion
W Schaper, H Frenzel, W Hort |
Basic Research in Cardiology | 1979 |
|
Mortality, Arrhythmias and Pump Failure in Acute Myocardial Infarction in Relation to Estimated Infarct Size
R Nordlander, O Nyquist |
Acta Medica Scandinavica | 1979 |
|
The multiple methodologies for creatine kinase isoenzymes — the final answer?
L Morin |
Clinical Biochemistry | 1979 |
|
The effect of sodium desoxycholate on the extraction of myocardial creatine phosphokinase and protein
BD Blackman, SG Rothstein |
Analytical Biochemistry | 1979 |
|
Sensitivity and specificity of MB creatine kinase activity determined with column chromatography
WE Shell, M Kligerman, MP Rorke, M Burnam |
The American Journal of Cardiology | 1979 |
|
Serum myocardial creatine kinase (CK-MB) after coronary arterial bypass surgery
HR Baur, BW Steele, KF Preimesberger, FL Gobel |
The American Journal of Cardiology | 1979 |
|
Two dimensional echocardiographic quantification of infarct size alteration by pharmacologic agents
RS Meltzer, JN Woythaler, AJ Buda, JC Griffin, WD Harrison, RP Martin, DC Harrison, RL Popp |
The American Journal of Cardiology | 1979 |
|
Prospective randomized trial of glucose-insulin-potassium in acute myocardial infarction
WJ Rogers, PH Segall, HG McDaniel, JA Mantle, RO Russell, CE Rackley |
The American Journal of Cardiology | 1979 |
|
ST isopotential precordial surface maps in patients with acute myocardial infarction
RG Murray, RM Peshock, RW Parkey, FJ Bonte, JT Willerson, CG Blomqvist |
Journal of Electrocardiology | 1979 |
|
International symposium on infarct size utrecht, holland- April 9-10, 1979 trends in infarct size reduction: From intention to intervention: Symposium on Infarct Size
CN D'Alnoncourt, R Cardinal |
Clinical Cardiology | 1979 |
|
Physiological modelling of serum creatine kinase kinetics after myocardial infarction
BP Murphy, BW Madsen, PL Thompson |
Computers and Biomedical Research | 1979 |
|
Effect of extension of infarction on serial CK activity
FR Cobb, RG Irvin, RC Hagerty, CC Roe |
Circulation | 1979 |
|
Scintigraphic characteristics of experimental myocardial infarct extension
MW Kronenberg, NE Wooten, GC Friesinger, DL Page, SB Higgins, JC Collins, JL O'Connor, RR Price, AB Brill |
Circulation | 1979 |
|
Quantification of myocardial infarction: template model for serial creatine kinase analysis
PW Armstrong, DG Watts, DC Hamilton, MA Chiong, JO Parker |
Circulation | 1979 |
|
The effect of delay in propranolol administration on reduction of myocardial infarct size after experimental coronary artery occlusion in dogs
M Miura, R Thomas, W Ganz, T Sokol, WE Shell, T Toshimitsu, AC Kwan, BN Singh |
Circulation | 1979 |
|
Spontaneous course of ST-segment elevation in acute anterior myocardial infarction
R Essen, W Merx, S Effert |
Circulation | 1979 |
|
Protracted ventricular tachcardia induced by premature stimulation of the canine heart after coronary artery occlusion and reperfusion
HS Karagueuzian, JJ Fenoglio, MB Weiss, AL Wit |
Circulation research | 1979 |
|
Extension of myocardial infarction: incidence and prognosis
TD Fraker, GS Wagner, RA Rosati |
Circulation | 1979 |
|
Enzymatic indices of myocardial necrosis: influence on short- and long-term prognosis after myocardial infarction
PL Thompson, EE Fletcher, V Katavatis |
Circulation | 1979 |
|
IX. Randomisierte Studie zur Wirkung von Nitroglycerin auf die CK- und CK-MB-Infarktgr��e. Vorl�ufige Ergebnisse
, E Berghof, P Wagner, H Klepzig, M Kaltenbach |
Klinische Wochenschrift | 1979 |
|
Thema: Der frische Herzmuskelinfarkt Herzruptur
W Schaper, MG Gottwik |
1979 | |
|
Experimental coronary artery occlusion: I. Measurement of infarct size
W Schaper, H Frenzel, W Hort |
Basic Research in Cardiology | 1979 |
|
Long-Term Preservation of Ischemic Myocardium after Experimental Coronary Artery Occlusion
D Maclean, MC Fishbein, E Braunwald, PR Maroko |
Journal of Clinical Investigation | 1978 |
|
Effects of Coronary Artery Reperfusion on Myocardial Infarct Size Calculated from Creatine Kinase
SF Vatner, H Baig, WT Manders, PR Maroko |
Journal of Clinical Investigation | 1978 |
|
Ischemic myocardial injury in cultured heart cells: Leakage of cytoplasmic enzymes from injured cells
D Acosta, M Puckett, R McMillin |
In Vitro | 1978 |
|
Stroke after acute myocardial infarction: relation to infarct size
PL Thompson, JS Robinson |
British medical journal | 1978 |
|
Natural history and evaluation of Q waves during acute myocardial infarction
AP Selwyn, K Fox, E Welman, JP Shillingford |
British heart journal | 1978 |
|
Effect of propranolol on enzymatic and histochemical estimates of infarct size in experimental myocardial infarction
GJ Jesmok, DC Warltier, GJ Gross, HF Hardman |
Basic Research in Cardiology | 1978 |
|
Comparison of CK-MB fractionation by antibody inhibition reaction and DEAE-Sephadex chromatography
K Itiaba, JC Crawhall |
Clinical Biochemistry | 1978 |
|
Approach to the estimation of myocardial infarct size by analysis of precordial S-T segment and R wave maps
H Henning, T Hardarson, G Francis, RA O'Rourke, W Ryan, J Ross |
The American Journal of Cardiology | 1978 |
|
Progressive nature of myocardial injury in selected patients with cardiogenic shock
AL Gutovitz, BE Sobel, R Roberts |
The American Journal of Cardiology | 1978 |
|
Creatine kinase isoenzymes in the assessment of heart disease
R Roberts, BE Sobel |
American Heart Journal | 1978 |
|
Factors influencing the reproducibility of creatine kinase projections by nonlinear curve fitting
WE Shell, MF Groseth-Robertson |
Computers and Biomedical Research | 1978 |
|
Effects of dimethyl propranolol (UM-272; SC-27761) on myocardial ischemic injury in the canine heart after temporary coronary artery occlusion
DD Ku, BR Lucchesi |
Circulation | 1978 |
|
Effects of lymphatic transport of enzyme on plasma creatine kinase time-activity curves after myocardial infarction in dogs
GL Clark, AK Robison, DR Gnepp, R Roberts, BE Sobel |
Circulation research | 1978 |
|
Myocardial infarction size from serial CPK: variability of CPK serum entry ratio with size and model of infarction
JA Cairns, E Missirlis, EL Fallen |
Circulation | 1978 |
|
Detection of serum cardiac myosin light chains in acute experimental myocardial infarction: radioimmunoassay of cardiac myosin light chains
BA Khaw, HK Gold, JT Fallon, E Haber |
Circulation | 1978 |
|
The clinical estimation of acute myocardial infarct size with 99mTechnetium pyrophosphate scintigraphy
DN Sharpe, EH Botvinick, DM Shames, A Norman, K Chatterjee, WW Parmley |
Circulation | 1978 |
|
Failure of high doses of propranolol to reduce experimental myocardial ischemic damage
T Peter, MK Heng, BN Singh, P Ambler, H Nisbet, R Elliot, RM Norris |
Circulation | 1978 |
|
Computed tomography for localization and sizing of experimental acute myocardial infarcts
WR Gray, LM Buja, HK Hagler, RW Parkey, JT Willerson |
Circulation | 1978 |
|
Untersuchungen zur Aktivit�tskinetik des Isoenzymes CK-MB im Serum nach Myokardinfarkt
D Neumeier, W Prellwitz, P Sandel, M Knedel |
Klinische Wochenschrift | 1978 |
|
Evaluation of myocardial damage during coronary artery grafting with serial determinations of serum CPK MB isoenzyme
E Delva, JG Maillé, BC Solymoss, M Chabot, CM Grondin, MG Bourassa |
The Journal of Thoracic and Cardiovascular Surgery | 1978 |
|
Factors Modifying Ischemic Injury in the Isolated Rat Heart
AP Waldenström, ÅC Hjalmarson |
Acta Medica Scandinavica | 1977 |
|
Technetium pyrophosphate scanning in acute myocardial infarction
WJ Kostuk, P Ko, D Deatrich |
Canadian Medical Association journal | 1977 |
|
Serum myoglobin level as diagnostic test in patients with acute myocardial infarction
MJ Stone, MR Waterman, D Harimoto, G Murray, N Willson, MR Platt, G Blomqvist, JT Willerson |
British heart journal | 1977 |
|
Evaluation of evolution of myocardial infarction by serial determinations of serum creatine kinase activity
M Inoue, M Hori, S Fukui, H Abe, T Minamino |
British heart journal | 1977 |
|
Chest pain in the early recognition of large infarcts
JR Ledwich |
Canadian Medical Association journal | 1977 |
|
Enzymatic diagnosis of infarction
BE Sobel |
The Western journal of medicine | 1977 |
|
Creatine phosphokinase-MB (CPK-MB) and the diagnosis of myocardial infarction
PM Guzy |
The Western journal of medicine | 1977 |
|
Radioimmunoassay of creatine kinase-B isoenzyme in human sera: results in patients with acute myocardial infarction
JT Willerson, MJ Stone, R Ting, A Mukherjee, CE Gomez-Sanchez, P Lewis, LB Hersh |
Proceedings of the National Academy of Sciences | 1977 |
|
Technetium pyrophosphate scanning in the detection of acute myocardial infarction: clinical experience
P Ko, WJ Kostuk, D Deatrich |
Canadian Medical Association journal | 1977 |
|
Myocardial infarction size: measurement and modification
JA Cairns |
Canadian Medical Association journal | 1977 |
|
Lack of protection of ischemic myocardium by verapamil in conscious dogs
RP Karlsberg, PD Henry, SA Ahmed, BE Sobel, R Roberts |
European Journal of Pharmacology | 1977 |
|
Myocardial infarct size: Clinicopathologic agreement and discordance
PJ Boor, ES Reynolds |
Human Pathology | 1977 |
|
Studies on isoprenaline-induced myocardial lesions 1. Quantitative evaluation by Mercurascan uptake
E Faltová, M Mráz, L Kronrád, L Protivová, J Šedivý |
Basic Research in Cardiology | 1977 |
|
Small animal model for myocardial infarction
RJ Staab, VD Lynch, C Lau-Cam, M Barletta |
Journal of Pharmaceutical Sciences | 1977 |
|
Acute-phase proteins from the liver and enzymes from myocardial infarction; a quantitative relationship
SJ Smith, G Bos, MR Esseveld, HG Eijk, J Gerbrandy |
Clinica Chimica Acta | 1977 |
|
Significance of Enzyme Release from Ischemic Isolated Rat Heart
AP Waldenström, ÅC Hjalmarson, M Jodal, J Waldenström |
Acta Medica Scandinavica | 1977 |
|
Effects of dobutamine in patients with acute myocardial infarction
TA Gillespie, HD Ambos, BE Sobel, R Roberts |
The American Journal of Cardiology | 1977 |
|
Dual myocardial imaging with technetium-99m pyrophosphate and thallium-201 for detecting, localizing and sizing acute myocardial infarction
H Henning, HR Schelbert, A Righetti, WL Ashburn, RA O'Rourke |
The American Journal of Cardiology | 1977 |
|
Factors influencing enzymatic estimates of infarct size
BE Sobel, J Markham, R Roberts |
The American Journal of Cardiology | 1977 |
|
Myocardial Ischemia
LD Hillis, E Braunwald |
New England Journal of Medicine | 1977 |
|
Favorable Effects of Hyaluronidase on Electrocardiographic Evidence of Necrosis in Patients with Acute Myocardial Infarction
PR Maroko, LD Hillis, JE Muller, L Tavazzi, GR Heyndrickx, M Ray, M Chiariello, A Distante, J Askenazi, J Salerno, J Carpentier, NI Reshetnaya, P Radvany, P Libby, DS Raabe, EI Chazov, P Bobba, E Braunwald |
New England Journal of Medicine | 1977 |
|
Radioimmunoassay for canine creatine kinase isoenzymes
R Roberts, A Painter |
Biochimica et Biophysica Acta (BBA) - Enzymology | 1977 |
|
Sizing acute myocardial infarcts: Present limitations and potential approaches
JT Willerson, RW Parkey, EM Stokely, FJ Bonte, LM Buja |
Postgraduate Medicine | 1977 |
|
Augmentation of serum CPK activity by digitalis in patients with acute myocardial infarction
Y Varonkov, WE Shell, V Smirnov, D Gukovsky, EI Chazov |
Circulation | 1977 |
|
The nature of disappearance of creatine kinase from the circulation and its influence on enzymatic estimation of infarct size
BE Sobel, J Markham, RP Karlsberg, R Roberts |
Circulation research | 1977 |
|
Correlation of angiographic estimates of myocardial infarct size and accumulated release of creatine kinase MB isoenzyme in man
WJ Rogers, HG McDaniel, LR Smith, JA Mantle, RO Russel, CE Rackley |
Circulation | 1977 |
|
Relationship between epicardial ST-segment elevation, regional myocardial blood flow, and extent of myocardial infarction in awake dogs
RG Irvin, FR Cobb |
Circulation | 1977 |
|
Infarct size estimated from serial serum creatine phosphokinase in relation to left ventricular hemodynamics
W Bleifeld, D Mathey, P Hanrath, H Buss, S Effert |
Circulation | 1977 |
|
Detection of myocardial infarction in vitro based on altered attenuation of ultrasound
JW Mimbs, DE Yuhas, JG Miller, AN Weiss, BE Sobel |
Circulation research | 1977 |
|
Detection of remote myocardial infarction in patients with positron emission transaxial tomography and intravenous 11C-palmitate
BE Sobel, ES Weiss, MJ Welch, BA Siegel, MM Ter-Pogossian |
Circulation | 1977 |
|
The relationship between enzymatic and histologic estimates of the extent of myocardial infarction in conscious dogs with permanent coronary occlusion
CR Roe, FR Cobb, CF Starmer |
Circulation | 1977 |
|
Individualized values for the disappearance rate parameter (Kd) in the enzymatic estimation of infarct size. A critique
AS Slutsky |
Circulation | 1977 |
|
The effect of propranolol on canine myocardial CPK distribution space and rate of disappearance
JA Cairns, GA Klassen |
Circulation | 1977 |
|
Mathematical modifications fail to improve CPK estimates of extent of infarct
CR Roe, CF Starmer, FR Cobb |
Circulation | 1977 |
|
Serial serum creatine phosphokinase MB isoenzyme activity after myocardial infarction. Studies in the baboon and man
WG Yasmineh, RB Pyle, JN Cohn, DM Nicoloff, NQ Hanson, BW Steele |
Circulation | 1977 |
|
Digitalis after AMI
D Shander |
Circulation | 1977 |
|
MI with normal coronaries in toxic cardiomyopathy
TJ Regan, CB Moschos, AB Weisse |
Circulation | 1977 |
|
Mitral valve prolapse and noncardiac symptoms
JP Liss |
Circulation | 1977 |
|
Verhandlungen der Deutschen Gesellschaft für innere Medizin: Dreiundachtzigster Kongreß gehalten zu Wiesbaden vom 17. – 21. April 1977
B Schlegel |
1977 | |
|
Effects of lidocaine and epinephrine on myocardial preservation following cardiopulmonary bypass in the dog
RG Schaub, GM Lemole, GC Pinder, P Black, GJ Stewart |
The Journal of Thoracic and Cardiovascular Surgery | 1977 |
|
Ischemia-induced alterations in myocardial (Na+ + K+)-ATPase and cardiac glycoside binding
GA Beller, J Conroy, TW Smith |
Journal of Clinical Investigation | 1976 |
|
Localization of cardiac myosin-specific antibody in myocardial infarction
BA Khaw, GA Beller, E Haber, TW Smith |
Journal of Clinical Investigation | 1976 |
|
Relationship between epicardial ST-segment elevation and myocardial ischemic damage after experimental coronary artery occlusion in dogs
MK Heng, BN Singh, RM Norris, MB John, R Elliot |
Journal of Clinical Investigation | 1976 |
|
APPLICATIONS AND LIMITATIONS OF ESTIMATION OF INFARCT SIZE FROM SERIAL CHANGES IN PLASMA CREATINE PHOSPHOKINASE ACTIVITY*
BE Sobel |
Acta Medica Scandinavica | 1976 |
|
Effect of acute carbon monoxide poisoning on serum lactate dehydrogenase and creatine phosphokinase
D Penney, T Maziarka |
Journal of Toxicology and Environmental Health | 1976 |
|
Estimation of infarct size from serum MB creatine phosphokinase activity: Applications and limitations
BE Sobel, R Roberts, KB Larson |
The American Journal of Cardiology | 1976 |
|
Lysosomal mechanisms in production of tissue damage during myocardial ischemia and the effects of treatment with steroids
AC Fox, S Hoffstein, G Weissmann |
American Heart Journal | 1976 |
|
Clinical chemical diagnosis and assessment of myocardial infarction
S Thunell |
Forensic Science | 1976 |
|
The effect of isosorbide dinitrate following experimental coronary occlusion
WD Meester, GL van Harn |
American Heart Journal | 1976 |
|
Effects of acetylsalicylic acid, dipyridamole, and hydrocortisone on epinephrine-induced myocardial injury in dogs
S Kraikitpanitch, CC Haygood, DJ Baxter, AA Yunice, RD Lindeman |
American Heart Journal | 1976 |
|
Medical Therapy of Acute Myocardial Infarction by Application of Hemodynamic Subsets
JS Forrester, G Diamond, K Chatterjee, HJ Swan |
New England Journal of Medicine | 1976 |
|
Evaluation of myocardial infarction with enzymatic indices
G Ahumada, R Roberts, BE Sobel |
Progress in Cardiovascular Diseases | 1976 |
|
Use of changes in the epicardial QRS complex to assess interventions which modify the extent of myocardial necrosis following coronary artery occlusion
LD Hillis, J Askenazi, E Braunwald, P Radvany, JE Muller, MC Fishbein, PR Maroko |
Circulation | 1976 |
|
Letter: Estimating MI size
RM Norris |
Circulation | 1976 |
|
The association of increased plasma MB CPK activity and irreversible ischemic myocardial injury in the dog
SA Ahmed, JR Williamson, R Roberts, RE Clark, BE Sobel |
Circulation | 1976 |
|
Letter: Ergotrate in coronary artery spasm
TO Cheng |
Circulation | 1976 |
|
Acute myocardial infarction. Evaluation of praecordial ST segment mapping
PL Thompson, V Katavatis |
Heart (British Cardiac Society) | 1976 |
|
Failure of ST segment elevation to predict severity of acute myocardial infarction
RM Norris, C Barratt-Boyes, MK Heng, BN Singh |
Heart (British Cardiac Society) | 1976 |
|
Radioimmunoassay for Creatine Kinase Isoenzymes
R Roberts, BE Sobel, CW Parker |
Science | 1976 |
|
Regional myocardial functional and electrophysiological alterations after brief coronary artery occlusion in conscious dogs
GR Heyndrickx, RW Millard, RJ McRitchie, PR Maroko, SF Vatner |
Journal of Clinical Investigation | 1975 |
|
Effects of free fatty acid and enzyme release in experimental glucose on myocardial infarction
JD Leiris, LH Opie, WF Lubbe |
Nature | 1975 |
|
Irreversible myocardial injury in anoxic perfused rat hearts
CE Ganote, R Seabra-Gomes, WG Nayler, RB Jennings |
The American Journal of Pathology | 1975 |
|
Creatine kinase release in acute myocardial infarction: correlation with clinical, electrocardiographic, and pathological findings
D Mathey, W Bleifeld, H Buss, P Hanrath |
British heart journal | 1975 |
|
Serum guanase activities after myocardial infarction
G Ellis, DM Goldberg |
Clinica Chimica Acta | 1975 |
|
ATP and muscle enzyme efflux after physical exertion
WH Thomson, JC Sweetin, IJ Hamilton |
Clinica Chimica Acta | 1975 |
|
Right Duct Lymph During and after Open-Heart Surgery
HE Hansson |
Scandinavian Cardiovascular Journal | 1975 |
|
Maximal revascularization (reperfusion) in intact conscious dogs after 2 to 5 hours of coronary occlusion
VS Mathur, GA Guinn, WH Burris |
The American Journal of Cardiology | 1975 |
|
An improved method for measuring the size of myocardial infarctions
AS Slutsky |
Medical Hypotheses | 1975 |
|
Lack of effect of ouabain on creatine phosphokinase efflux from skeletal muscle
HY Meltzer |
Biochemical Pharmacology | 1975 |
|
Evaluation of precordial electrocardiographic mapping as a means of assessing changes in myocardial ischemic injury
JE Muller, PR Maroko, E Braunwald |
Circulation | 1975 |
|
An improved basis for enzymatic estimation of infarct size
R Roberts, PD Henry, BE Sobel |
Circulation | 1975 |
|
Noninvasive quantitation of myocardial infarction with technetium 99m pyrophosphate
EH Botvinick, D Shames, H Lappin, JV Tyberg, R Townsend, WW Parmley |
Circulation | 1975 |
|
Clinical measurement of myocardial infarct size. Modification of a method for the estimation of total creatine phosphokinase release after myocardial infarction
RM Norris, RM Whitlock, C Barratt-Boyes, CW Small |
Circulation | 1975 |
|
Reduction of infarct size by oxygen inhalation following acute coronary occlusion
PR Maroko, P Radvany, E Braunwald, SL Hale |
Circulation | 1975 |
|
Effects of glucose, insulin and potassium infusion on tissue metabolic changes within first hour of myocardial infarction in the baboon
LH Opie, K Bruyneel, P Owen |
Circulation | 1975 |
|
A sensitivity analysis of enzymatic estimation of infarct size
CR Roe, CF Starmer |
Circulation | 1975 |
|
Quantitation of infarct size in man by means of plasma enzyme levels
SA Witteveen, HC Hemker, L Hollaar, WT Hermens |
Heart (British Cardiac Society) | 1975 |
|
Relation between infarct size and ventricular arrhythmia
R Roberts, A Husain, HD Ambos, GC Oliver, JR Cox, BE Sobel |
Heart (British Cardiac Society) | 1975 |
|
Deleterious effects due to hemorrhage after myocardial reperfusion
GF Bresnahan, R Roberts, WE Shell, J Ross, BE Sobel |
The American Journal of Cardiology | 1974 |
|
Quantification of serum creatine phosphokinase isoenzyme activity
R Roberts, PD Henry, SA Witteeveen, BE Sobel |
The American Journal of Cardiology | 1974 |
|
Reduction of Myocardial-Infarct Size
E Braunwald |
New England Journal of Medicine | 1974 |
|
Protection of Jeopardized Ischemic Myocardium by Reduction of Ventricular Afterload
WE Shell, BE Sobel |
New England Journal of Medicine | 1974 |
|
Radioisotopic Assessment of Myocardial Infarction
RW Myers, RE Goldstein |
New England Journal of Medicine | 1974 |
|
The Reduction of Infarct Size — An Idea Whose Time (For Testing) Has Come
E Braunwald, PR Maroko |
Circulation | 1974 |
|
Das Arterielle System
R Thauer, K Pleschka |
1974 | |
|
Early Estimation of Myocardial Damage in Conscious Dogs and Patients with Evolving Acute Myocardial Infarction
WE Shell, JF Lavelle, JW Covell, BE Sobel |
Journal of Clinical Investigation | 1973 |
|
Enzyme efflux and clearance
JC Sweetin, WH Thomson |
Clinica Chimica Acta | 1973 |
|
Contributions of computer simulation to clinical enzymology
D Garfinkel |
Human Pathology | 1973 |
|
Deleterious effects of increased heart rate on infarct size in the conscious dog
WE Shell, BE Sobel |
The American Journal of Cardiology | 1973 |
|
Effect of pharmacologic agents on the function of the ischemic heart
PR Maroko, P Libby, E Braunwald |
The American Journal of Cardiology | 1973 |
|
Altered hemoglobin oxygen affinity in patients with acute myocardial infarction
WJ Kostuk, K Suwa, EF Bernstein, BE Sobel |
The American Journal of Cardiology | 1973 |
|
Carbon Monoxide Inhalation Effects Following Myocardial Infarction in Monkeys
DA DeBias, CM Banerjee, NC Birkhead, WV Harrer, LA Kazal |
Archives of Environmental Health An International Journal | 1973 |
|
The Enzymatic and Immunologic Detection of Myocardial Injury: Selected Considerations
L Cohen, J Morgan |
Medical Clinics of North America | 1973 |
|
The Cardiac Care Unit in 1973
BE Sobel |
Hospital Practice | 1973 |
|
The Importance of Identification of the Myocardial-Specific Isoenzyme of Creatine Phosphokinase (MB Form) in the Diagnosis of Acute Myocardial Infarction
GS Wagner, CR Roe, LE Limbird, RA Rosati, AG Wallace |
Circulation | 1973 |
|
Jeopardized, Blighted, and Necrotic Myocardium
BE Sobel, WE Shell |
Circulation | 1973 |
|
Time Course of Enzyme Escape via Heart Lymph Following Myocardial Infarction in the Dog
P Malmberg |
Scandinavian Journal of Clinical & Laboratory Investigation | 1972 |
|
Sinoventricular conduction during atrial arrest
LB Jacobson |
Journal of Electrocardiology | 1972 |
|
Hemodynamic Changes in Acute Myocardial Infarction
J Ross |
Hospital Practice | 1972 |
|
Biochemical and Morphologic Changes in Infarcting Myocardium
BE Sobel |
Hospital Practice | 1972 |
|
Changes in Left Ventricular Performance from Early after Acute Myocardial Infarction to the Convalescent Phase
SH Rahimtoola, MM Digilio, A Ehsani, HS Loeb, KM Rosen, RM Gunnar |
Circulation | 1972 |
|
Estimation of Infarct Size in Man and its Relation to Prognosis
BE Sobel, GF Bresnahan, WE Shell, RD Yoder |
Circulation | 1972 |
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