Rheumatoid synovial collagenase obtained from culture medium can be separated by Sephadex gel filtration into two peaks of enzyme activity. These have been designated as fast-moving and slow-moving rheumatoid synovial collagenases on the basis of their electrophoretic mobility on polyacrylamide gels. The slow-moving rheumatoid synovial collagenase has been highly purified by affinity chromatography on collagen conjugated to Sepharose and used to prepare a monospecific anti-synovial collagenase antiserum.
Eugene A. Bauer, Arthur Z. Eisen, John J. Jeffrey
Title and authors | Publication | Year |
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Methods in Enzymology
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Protein Engineering for Therapeutics Part B | 2012 |
Advances in Immunology
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Advances in Immunology Volume 110 | 2011 |
Treatment of Destructive Arthritic Disorders with MMP Inhibitors
RA Greenwald |
Annals of the New York Academy of Sciences | 1994 |
Journal of Chromatography Library
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Journal of Chromatography Library | 1987 |
Leukocyte elastase and free collagenase activity in synovial effusions: Relation to numbers of polymorphonuclear leukocytes
G Cohen, K Fehr, FJ Wagenhuser |
Rheumatology International | 1983 |
Study of enzyme inhibitors in the rheumatoid pannus-cartilage area
ED Flory, KD Muirden |
Rheumatology International | 1983 |
Identification of plasma kallikrein as an activator of latent collagenase in rheumatoid synovial fluid
H Nagase, TE Cawston, MD Silva, AJ Barrett |
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology | 1982 |
Enhanced neutral protease activity in proliferating rheumatoid synovial cells
VB Hatcher, JP Borg, M Levitt, C Smith |
Arthritis & Rheumatism | 1981 |
Die Kollagenaseaktivität beim Kreuzbandriß des Hundes und ihre Hemmung in vitro
GW Niebauer, G Lubec |
Zentralblatt für Veterinärmedizin Reihe A | 1980 |
Experimental Arthritis Induced by Granulocyte Collagenase
C Steffen, J Menzel, J Zeitlhofer, J Smolen, G Lanzer |
Scandinavian Journal of Rheumatology | 1980 |
Activation in vitro of rheumatoid synovial collagenase from cell cultures
CA Vater, CL Mainardi, ED Harris |
Journal of Clinical Investigation | 1978 |
Pathology of collagen degradation. A review
R Pérez-Tamayo |
The American Journal of Pathology | 1978 |
Increased frequency of the MZ phenotype of alpha-1-protease inhibitor in juvenile chronic polyarthritis
P Arnaud, RM Galbraith, WP Faulk |
Journal of Clinical Investigation | 1977 |
Localization of collagenase in human middle ear cholesteatoma
M Abramson, CC Huang |
The Laryngoscope | 1977 |
QUANTITATION AND IMMUNOCYTOCHEMICAL LOCALIZATION OF HUMAN SKIN COLLAGENASE IN BASAL CELL CARCINOMA
EA Bauer, JM Gordon, ME Riddick, AZ Eisen |
Journal of Investigative Dermatology | 1977 |
Factors Influencing the Apparent Molecular Weight of Collagenase Produced by Human-Skin Explants
C FIEDLER-NAGY, JW COFFEY, RA SALVADOR |
European Journal of Biochemistry | 1977 |
The biology of the rheumatoid synovial cell
DM Haselwood, JJ Castles |
The Western journal of medicine | 1977 |
Collagenase Studies in bones of guinea pigs*
SB Heard |
Journal of Oral Pathology and Medicine | 1976 |
In vivo and in vitro stimulation of collagenase production by rabbit alveolar macrophages
H Birkedal-Hansen, CM Cobb, RE Taylor, HM Fullmer |
Archives of Oral Biology | 1976 |
COLLAGENASE PRODUCTION BY HUMAN SYNOVIAL TISSUES
SM Krane |
Annals of the New York Academy of Sciences | 1975 |
Hydroxyproline Levels and Collagenolytic Activity in Synovial Fluids of Patients with Rheumatic Diseases
J Wize, I Sopata, J Gietka, S Jakubowski, D Kruze |
Scandinavian Journal of Rheumatology | 1975 |
Rabbit collagenase. Immunological identity of the enzymes released from cells and tissues in normal and pathological conditions
Z Werb, JJ Reynolds |
Biochemical Journal | 1975 |
Purification and characterization of a collagenase extracted from rabbit tumours
PA McCroskery, JF Richards, ED Harris |
Biochemical Journal | 1975 |
Interaction of cartilage proteoglycans with collagen-substituted agarose gels
RA Greenwald, CE Schwartz, JO Cantor |
Biochemical Journal | 1975 |
Inhibition of human collagenase activity by a small molecular weight serum protein
DE Woolley, DR Roberts, JM Evanson |
Biochemical and Biophysical Research Communications | 1975 |
IMMUNOCYTOCHEMICAL LOCALIZATION OF COLLAGENASE IN HUMAN SKIN AND FIBROBLASTS IN MONOLAYER CULTURE
ME Reddick, EA Bauer, AZ Eisen |
Journal of Investigative Dermatology | 1974 |
STUDIES ON ANIMAL COLLAGENASE
G Usuku, M Honya, I Oyamada, T Ogata |
Pathology International | 1974 |
The interaction of alpha2-macroglobulin with proteinases. Binding and inhibition of mammalian collagenases and other metal proteinases
Z Werb, MC Burleigh, AJ Barrett, PM Starkey |
Biochemical Journal | 1974 |
Solid-phase radioimmunoassay of rat skin collagenase comparative studies and in vivo measurement of the enzyme
AZ Eisen, J Nepute, GP Stricklin, EA Bauer, JJ Jeffrey |
Biochimica et Biophysica Acta (BBA) - Enzymology | 1974 |
Collagenases
ED Harris, SM Krane |
New England Journal of Medicine | 1974 |
Animal collagenases: Specificity of action, and structures of the substrate cleavage site
J Gross, E Harper, ED Harris, PA McCroskery, JH Highberger, C Corbett, AH Kang |
Biochemical and Biophysical Research Communications | 1974 |
The Neutral Proteases of Human Granulocytes. Isolation and Partial Characterization of Two Granulocyte Collagenases
K Ohlsson, I Olsson |
European Journal of Biochemistry | 1973 |
Homeostasis in Extracellular Tissues: Insights from Studies on Collage
PF Davison, ED Harris |
Critical Reviews in Biochemistry and Molecular Biology | 1973 |
Differences in the physical properties of collagenases isolated from rheumatoid synovium and human skin
DE Woolley, RW Glanville, JM Evanson |
Biochemical and Biophysical Research Communications | 1973 |
Proteinase inhibitors in human synovial fluid
G Shtacher, R Maayan, G Feinstein |
Biochimica et Biophysica Acta (BBA) - Protein Structure | 1973 |
Vertebrate collagenase: Further characterization and the significance of its latent form in vivo
Y Nagai |
Molecular and Cellular Biochemistry | 1973 |
A collagenolytic system produced by primary cultures of rheumatoid nodule tissue
ED Harris |
Journal of Clinical Investigation | 1972 |
Further studies on the nature of the components in serum which inhibit mouse bone collagenase
S Sakamoto, S Goldhaber, MJ Glimcher |
Calcified Tissue Research | 1972 |
REGULATION OF VERTEBRATE COLLAGENASE ACTIVITY IN VIVO AND IN VITRO
EA Bauer, AZ Eisen, JJ Jeffrey |
Journal of Investigative Dermatology | 1972 |
Role of granulocyte collagenase in collagen degradation
GS Lazarus, JR Daniels, J Lian, MC Burleigh |
The American Journal of Pathology | 1972 |
Collagenase in carcinoma cells
ED Harris, CS Faulkner, S Wood |
Biochemical and Biophysical Research Communications | 1972 |
Collagenase, procollagenase and activator relationships in tadpole tissue cultures
E Harper, J Gross |
Biochemical and Biophysical Research Communications | 1972 |
Characterization of a collagenase from rat skin
Y Tokoro, AZ Eisen, JJ Jeffrey |
Biochimica et Biophysica Acta (BBA) - Enzymology | 1972 |
Radioimmunoassay of Human Collagenase
EA Bauer, AZ Eisen, JJ Jeffrey |
The Journal of biological chemistry | 1972 |