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Citations to this article

NB1, a new neutrophil-specific antigen involved in the pathogenesis of neonatal neutropenia
Parviz Lalezari, … , Georgette B. Murphy, Fred H. Allen Jr.
Parviz Lalezari, … , Georgette B. Murphy, Fred H. Allen Jr.
Published May 1, 1971
Citation Information: J Clin Invest. 1971;50(5):1108-1115. https://doi.org/10.1172/JCI106582.
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NB1, a new neutrophil-specific antigen involved in the pathogenesis of neonatal neutropenia

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Abstract

A new human antigen is reported which is present only on blood neutrophils. A neutrophil-specific antigen, designated NA1, has previously been identified in two unrelated families, and was shown to be involved in fetomaternal incompatibility and the development of isoimmune neonatal neutropenia in five newborns. In the present paper, a second antigen, designated NB1, is identified in four families with seven affected children. Antibodies that react with this second antigen are shown to produce selective agglutination of neutrophils but not other blood cells. They are neither absorbed by cells prepared from solid tissues nor by non-neutrophilic blood cells.

Authors

Parviz Lalezari, Georgette B. Murphy, Fred H. Allen Jr.

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Year: 2025 2024 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004 2003 2002 2001 2000 1999 1992 1988 1987 1986 1985 1984 1983 1981 1980 1979 1978 1977 1975 1974 1973 1972 1949 Total
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