Effect of insulin and acute diabetes on plasma FFA and ketone bodies in the fasting rat

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Abstract

The metabolism of FFA and ketone bodies was studied in fasted rats by infusing at a constant rate tracer amounts of FFA-3H, β-hydroxybutyrate-14C or acetoacetate-14C for periods up to 2 hr. Blood that was removed for analyses was replaced by continuous transfusion. The rates of turnover of FFA, β-hydroxybutyrate, and acetoacetate in rats fasted for 2 days were, respectively, 3.2, 5.6, and 2.5 μmoles/100 g body weight per min.

Authors

Frederick A. Bieberdorf, Sidney S. Chernick, Robert O. Scow