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Citations to this article

Conversion of Thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects
Lewis E. Braverman, … , Sidney H. Ingbar, Kenneth Sterling
Lewis E. Braverman, … , Sidney H. Ingbar, Kenneth Sterling
Published May 1, 1970
Citation Information: J Clin Invest. 1970;49(5):855-864. https://doi.org/10.1172/JCI106304.
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Research Article Article has an altmetric score of 19

Conversion of Thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects

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Abstract

Studies of the possibility that thyroxine (T4) is converted to 3.5,3′-triiodo-L-thyronine (T3) in the extrathyroidal tissues in man have been conducted in 13 patients, all but two of whom were athyreotic or hypothyroid, and all of whom were receiving at least physiological replacement doses of synthetic sodium-L-thyroxine.

Authors

Lewis E. Braverman, Sidney H. Ingbar, Kenneth Sterling

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In vitro Study on Thyroid Hormone Metabolism of Human Placenta in Early Pregnancy
T Adachi, M Maeda, T Nomoto, F Tsukahara, S Sakamoto, Y Takeda
Asia-Oceania Journal of Obstetrics and Gynaecology 1986
Stimulation of mouse liver glutathione S-transferase activity in propylthiouracil-treated mice in vivo by tri-iodothyronine
MT Williams, H Carrington, A Herrera
Biochemical Journal 1986
Schilddrüsenreaktionen der Wistar-Ratte im Tagesgang nach Gangliektomie unter Normaltemperatur und Kälteexposition unter Berücksichtigung des Einflusses der Epiphysis cerebri
VE Peschke, D Peschke, J Peil, C Rúzsás, B Mess
Acta Histochemica 1986
Genotype dependency of the thermic effect of a meal and associated hormonal changes following short-term overfeeding
ET Poehlman, A Tremblay, E Fontaine, JP Després, A Nadeau, J Dussault, C Bouchard
Metabolism 1986
Trace Elements in Human and Animal Nutrition
BS Hetzel, GF Maberly
Trace Elements in Human and Animal Nutrition 1986
Thyroid Functions in Chronic Liver Diseases
AA Hafiez, MA Razzak, MR Awadain, M Fahmy, FA Halawa, AM Khalil, H Nasr
Isotopenpraxis Isotopes in Environmental and Health Studies 1986
Frontiers in Thyroidology
G Medeiros-Neto, E Gaitan
1986
Clinical Endocrinology
A Labhart
Clinical Endocrinology 1986
Low T3 syndrome in patients following major surgery
A Tsuchiya, PE Goretzki, M Gramse, K Joseph, RA Wahl
The Japanese Journal of Surgery 1985
6 Diseases of the thyroid gland
PW Ladenson
Clinics in Endocrinology and Metabolism 1985
Natural history of primary myxedema
PA Bastenie, M Bonnyns, L Vanhaelst
The American Journal of Medicine 1985
Biochemical Actions of Hormones
D Marver
Biochemical Actions of Hormones 1985
Extrathyroidal conversion of thyroxine to triiodothyronine in Calotes versicolor
A Kar, A Chandola-Saklani
General and Comparative Endocrinology 1985
Neurochemical Systems
A Lajtha
1985
Management of patients with congenital hypothyroidism
GJ Frost, JM Parkin
BMJ : British Medical Journal 1985
Contemporary Endocrinology
SH Ingbar
1985
Peripheral tissue mechanism for maintenance of serum triiodothyronine values in a thyroxine-deficient state in man
SM Lum, JT Nicoloff, CA Spencer, EM Kaptein
Journal of Clinical Investigation 1984
Radioimmunoassay of Human Thyrotropin: Analytical and Clinical Developments
RE Wehmann, BC Nisula
Critical Reviews in Clinical Laboratory Sciences 1984
Serum thyroid hormone changes during whole body hyperthermia
PH Konits, BP Hamilton, ES Pruce, M Whitacre, DH van Echo
Cancer 1984
Effects of electrical stimulationin vivoofM. pectoralison carbohydrate metabolism with to certain liver and blood values in the pigeon
B Pilo, TM John, JC George, RJ Etches
Archives Of Physiology And Biochemistry 1984
Structural requirements of thiol compounds in the inhibition of human liver iodothyronine 5'-deiodinase
R Harbottle, SJ Richardson
Biochemical Journal 1984
Reverse Triiodothyronine in Protein Energy Malnutrition
AA Hafiez, E Abdel-Salam, EZ Abbas, FA Halawa, N El-Hefnawy
Isotopenpraxis Isotopes in Environmental and Health Studies 1984
Extrathyroidal thyroxine-5′-monodeiodinase activity in cattle
S Kahl, J Bitman, TS Rumsey
Domestic Animal Endocrinology 1984
Studies on the conversion of thyroxine to 3,5,3′-triiodothyronine in normal and thyroidectomized chickens
P Rudas, G Pethes
General and Comparative Endocrinology 1984
Thyroid hormone changes in the bobwhite (Colinus virginianus) after hatching
DE Spiers, RK Ringer
General and Comparative Endocrinology 1984
Endocrine Disorders
LH Rees
Endocrine Disorders 1984
Low Triiodothyronine and Raised Reverse Triiodothyronine Levels in Patients Over Fifty Years of Age Who Have Type II Diabetes Mellitus: Influence of Metabolic Control, Not Age
UM Kabadi, BN Premachandra
Journal of the American Geriatrics Society 1984
Thyroid Function in Juvenile Diabetes
S Castells
Pediatric Clinics of North America 1984
Models of the Control of Production, Distribution and Metabolism of Thyroid Hormones in Several Species: Comparative Aspects
JJ DiStefano
IFAC Proceedings Volumes 1984
Total and free thyroid hormone concentrations in patients receiving maintenance replacement treatment with thyroxine
CJ Pearce, RL Himsworth
BMJ : British Medical Journal 1984
[Diagnostic procedure in suspected functional disorders of the thyroid gland].
Hesch RD
Klinische Wochenschrift 1984
Thyroid hormones in chronic heat exposed men
A Gertner, R Israeli, A Lev, Y Cassuto
International Journal of Biometeorology 1983
Plasma membrane transport of thyroid hormone: its possible pathophysiological significance
EP Krenning, R Docter, TJ Visser, G Hennemann
Journal of Endocrinological Investigation 1983
Regulation of conversion of thyroxine to triiodothyronine in perfused rat kidney
DC Ferguson, AS Jennings
American journal of physiology. Endocrinology and metabolism 1983
Iodothyronine homeostasis in rat brain during hypo- and hyperthyroidism
MB Dratman, FL Crutchfield, JT Gordon, AS Jennings
American journal of physiology. Endocrinology and metabolism 1983
Thyroid Hormones and the Liver
P Sheridan
1983
Low serum 3, 5, 3′-triiodothyronine (T3) and raised 3, 3′, 5′-triidothyronine (reverse T3 or RT3) in diabetes mellitus: Normalization on improvement in hyperglycemia
UM Kabadi, BN Premachandra, M Maayan
Acta Diabetologica Latina 1982
Early peripheral responses to intravenous L-thyroxine in primary hypothyroidism
PW Ladenson, PD Goldenheim, DS Cooper, MA Miller, EC Ridgway
The American Journal of Medicine 1982
Thyroid function tests in nonthyroidal disease
JH Oppenheimer
Journal of Chronic Diseases 1982
Elevated serum thyroxine concentration in patients receiving “replacement” doses of levothyroxine
JC Ingbar, M Borges, S Iflah, RE Kleinmann, LE Braverman, SH Ingbar
Journal of Endocrinological Investigation 1982
Seasonal variations in extrathyroidal conversion of thyroxine to tri-iodothyronine and migratory disposition in redheaded bunting
VK Pathak, A Chandola
General and Comparative Endocrinology 1982
Thyroid Hormones and Antithyroid Drugs
RA Rosychuk
Veterinary Clinics of North America Small Animal Practice 1982
Thyroid Function in the Elderly
V Burroughs, L Shenkman
The American Journal of the Medical Sciences 1982
Conversion and binding of tetraiodothyronine in developing rat brain
T Valcana
Neurochemical Research 1981
What is the best test for monitoring levothyroxine therapy?
MM Wong, R Volpé
Canadian Medical Association journal 1981
Alterations in hepatic monodeiodination of iodothyronines in the diabetic rat
IJ Chopra, W Wiersinga, H Frank
Life Sciences 1981
Effects of dietary manipulation on the generation of 3,5,3'-triiodothyronine from thyroxine in rat liver preparations
A Balsam, F Sexton, SH Ingbar
Life Sciences 1981
Conversion of l-thyroxine to triiodo-l-thyronine in rainbow trout (Salmo gairdneri) liver and kidney homogenates
JF Leatherland
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry 1981
Thyroid hormone binding to plasma membrane preparations: studies in different thyroid states and tissues
J Gharbi-Chihi, J Torresani
Journal of Endocrinological Investigation 1981
Inhibition of rat hepatic thyroxine 5′-monodeiodinase by propylthiouracil: relation to site of interaction of thyroxine and glutathione
T Yamada, IJ Chopra, N Kaplowitz
Journal of Endocrinological Investigation 1981
Effect of thyroxine on nerve growth factor concentration in neonatal mouse brain
P Walker, NL Weil, ME Weichsel, DA Fischer
Life Sciences 1981
Predominant T3 synthesis in the metastatic thyroid carcinoma in a patient with T3-toxicosis
T Nakashima, K Inoue, A Shiro-ozu, M Yoshinari, K Okamura, M Itoh
Metabolism 1981
Hepatic throxine (T4) uptake as a mechanism for regulation of triiodothyronine (T3) generation in rat liver slices
JT Nicoloff, DW Warren, L Mizuno, CA Spencer, EM Kaptein
Life Sciences 1981
Conversion of thyroxine to triiodothyronine in an adult amphibian, Bufo marinus
CT Sawin, JL Bolaffi, P Bacharach, V Lance
General and Comparative Endocrinology 1981
Hypothalamic control of endocrine thermogenesis
PR Marques, P Illner, DD Williams, WL Gren, JW Kendall, SL Davis, DG Johnson, CC Gale
American journal of physiology. Endocrinology and metabolism 1981
Prophylaxis of recurrent goiter by high-dose L-thyroxine
P Goretzki, HD Roeher, G Horeyseck
World Journal of Surgery 1981
Thyroid and Parathyroid Diseases
BH Forman, DD Roberts
Otolaryngologic Clinics of North America 1981
Thyroid Function in a Uremic Rat Model EVIDENCE SUGGESTING TISSUE HYPOTHYROIDISM
VS Lim, C Henriquez, H Seo, S Refetoff, E Martino
Journal of Clinical Investigation 1980
Activation and inactivation of thyroxine by cultured rat hepatoma cells
K Sorimachi, A Niwa, Y Yasumura
Biochimica et Biophysica Acta (BBA) - General Subjects 1980
Alterations in monodeiodination of iodothyronines in the fasting rat: Effects of reduced nonprotein sulfhydryl groups and hypothyroidism
IJ Chopra
Metabolism 1980
Induction of Sustained Hyperthyroidism and Hypothyroidism in the Turkey: Physiological and Biochemical Observations
JP Bilezikian, JN Loeb, DE Gammon
Poultry science 1980
Effect of Dietary Thyroid Hormone on Growth and Feed Efficiency of Broilers
J May
Poultry science 1980
Thyroxine replacement therapy: prescribing patterns and problems in 2710 patients. Scottish Automated Follow-up Register Group.
British medical journal 1980
The Role of Sulfhydryl Groups on the Impaired Hepatic 3′,3,5-Triiodothyronine Generation from Thyroxine in the Hypothyroid, Starved, Fetal, and Neonatal Rodent
AR Harris, SL Fang, L Hinerfeld, LE Braverman, AG Vagenakis
Journal of Clinical Investigation 1979
Observations on the factors that control the generation of triiodothyronine from thyroxine in rat liver and the nature of the defect induced by fasting
A Balsam, SH Ingbar
Journal of Clinical Investigation 1979
Dietary-induced alterations in thyroid hormone metabolism during overnutrition
E Danforth, ES Horton, M O'Connell, EA Sims, AG Burger, SH Ingbar, L Braverman, AG Vagenakis
Journal of Clinical Investigation 1979
Regulation of the Conversion of Thyroxine to Triiodothyronine in the Perfused Rat Liver
AS Jennings, DC Ferguson, RD Utiger
Journal of Clinical Investigation 1979
Semistarvation: an overview of an old problem
JL Barbosa-Saldivar, TB van Itallie
Bulletin of the New York Academy of Medicine 1979
Evidence for the rapid direct control both in vivo and in vitro of the efficiency of oxidative phosphorylation by 3,5,3'-tri-iodo-L-thyronine in rats
R Palacios-Romero, J Mowbray
Biochemical Journal 1979
Effect of insulin-induced hypoglycemia on the serum concentrations of thyroxine, triiodothyronine and reverse triiodothyronine
GJ Tevaarwerk, CJ Hurst, P Uksik, L Reese
Canadian Medical Association journal 1979
Impaired 3,5,3′-triiodothyronine (T3) production in diabetic patients
CS Pittman, AK Suda, JB Chambers, GY Ray
Metabolism 1979
Non-thyrotropic pituitary cells in culture convert T4 to T3
S Melmed, G Kurtzman, A Reed, JH Hershman
Life Sciences 1979
4 Investigation and treatment of hypothyroidism
R Capiferri, D Evered
Clinics in Endocrinology and Metabolism 1979
10 The thyroid
LE Braverman, AG Vagenakis
Clinics in Endocrinology and Metabolism 1979
9 Ageing and endocrine function
PJ Davis
Clinics in Endocrinology and Metabolism 1979
Comparison of l-Thyroxine and 3,5,3' triiodo-l-thyronine kinetics in fed and starved rainbow trout (Salmo gairdneri)
JG Eales
Comparative Biochemistry and Physiology Part A: Physiology 1979
Control and Dynamic Systems
PH Mak, JJ Distefano
Control and Dynamic Systems 1979
The effect of T3 and reverse T3 administration on muscle protein catabolism during fasting as measured by 3-methylhistidine excretion
KD Burman, L Wartofsky, RE Dinterman, P Kesler, RW Wannemacher
Metabolism 1979
Phenolic and nonphenolic ring deiodinations of iodothyronines in cultured hepatocarcinoma cell hemogenate from monkey
K Sorimachi, J Robbins
Biochimica et Biophysica Acta (BBA) - General Subjects 1979
The combined radioimmunoassay of triiodothyronine and thyroxine
CE Denning, LA Schick, RC Boguslaski
Clinica Chimica Acta 1979
Proceedings of the 1978 Laurentian Hormone Conference
P Felig, RS Sherwin, V Soman, J Wahren, R Hendler, L Sacca, N Eigler, D Goldberg, M Walesky
Proceedings of the 1978 Laurentian Hormone Conference 1979
Iatrogenic and Factitious Thyroidal Disease
HE Zellmann
Medical Clinics of North America 1979
Changes in extrathyroidal conversion of thyroxine (T4) to 3,3′,5-triiodothyronine (T3) in vitro during development and aging of the rat
H Ooka
Mechanisms of Ageing and Development 1979
Thyroxine Increases Nerve Growth Factor Concentration in Adult Mouse Brain
P Walker, ME Weichsel, DA Fisher, SM Guo, DA Fisher
Science 1979
l-Triiodothyronine and l-Reverse-Triiodothyronine Generation in the Human Polymorphonuclear Leukocyte
KA Woeber
Journal of Clinical Investigation 1978
Carbon-13 NMR studies of thyroid hormones and model compounds. The conformational analysis of diphenyl ethers
PH Mazzocchi, HL Ammon, E Colicelli
Organic Magnetic Resonance 1978
The Preferential Role of Triiodothyronine in the Regulation of Basal Metabolic Rate in Hyper- and Hypothyroidism
K Johansen, JM Hansen, L Skovsted
Acta Medica Scandinavica 1978
Serum thyroid hormones in patients on replacement or suppressive doses of L-thyroxine
S Rosenblatt, JM Hershman
The Western journal of medicine 1978
Preliminary report on the use of propranolol in thyrotoxicosis: I. Effect on serum thyroxine, triiodothyronine and reverse triiodothyronine concentrations
GJ Tevaarwerk, MH Malik, D Boyd
Canadian Medical Association journal 1978
Sequential deiodination of thyroxine in rat liver homogenate
TJ Visser, D Fekkes, R Docter, G Hennemann
Biochemical Journal 1978
Isolation of labeled triiodothyronine from serum using affinity chromatography: Application to the estimation of the peripheral T4 to T3 conversion in rats
CJ Zimmerman, M Izumi, PR Larsen
Metabolism 1978
Recent developments in thyroid hormone metabolism: Interpretation and significance of measurements of reverse T3, 3,3′T2, and thyroglobulin
KD Burman
Metabolism 1978
Antithyroid drugs
B Marchant, JF Lees, WD Alexander
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology 1978
Molecular mechanisms at the tissue level in hyperthyroidism
JH Oppenheimer, WH Dillmann
Clinics in Endocrinology and Metabolism 1978
Physiologic and biochemical actions of thyroid hormone
HL Schwartz, JH Oppenheimer
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology 1978
Why does anyone still use desiccated thyroid USP?
IM Jackson, WE Cobb
The American Journal of Medicine 1978
Induction of thyroxine and triiodothyronine release by thyrotrophin-releasing hormone in the hen
H Klandorf, PJ Sharp, R Sterling
General and Comparative Endocrinology 1978
Regulation of thyroid hormone metabolism in rat liver fractions
B Höffken, R Ködding, A Mühlen, T Hehrmann, J Harald, RD Hesch
Biochimica et Biophysica Acta (BBA) - General Subjects 1978
Extrathyroidal conversion of thyroxine to triiodothyronine in a bird: The peking duck
HS Astier, WS Newcomer
General and Comparative Endocrinology 1978
Optimal control policies for the prescription of thyroid hormones
PH Mak, JJ DiStefano
Mathematical Biosciences 1978
Effect of starvation, nutriment replacement, and hypothyroidism on in vitro hepatic T4 to T3 conversion in the rat
AR Harris, SL Fang, AG Vagenakis, LE Bravernan
Metabolism 1978
Proceedings of the 1977 Laurentian Hormone Conference
IJ Chopra, DH Solomon, U Chopra, SY Wu, DA Fisher, Y Nakamura
Proceedings of the 1977 Laurentian Hormone Conference 1978
Receptors and Hormone Action
AW Norman, WR Wecksler
Receptors and Hormone Action 1978
Thyroid function tests: What they do and do not measure
TJ Merimee
Postgraduate Medicine 1978
Synaptosomal [125I]triiodothyronine after intravenous [125I]thyroxine
MB Dratman, FL Crutchfield
American journal of physiology. Endocrinology and metabolism 1978
Conversion of T3 and rT3 to 3,3′-T2: pH dependency
B Höffken, R Ködding, J Köhrle, RD Hesch
Clinica chimica acta; international journal of clinical chemistry 1978
Response to thyrotrophin-releasing hormone in atrial dysrhythmias
C Symons, A Myers, D Kingstone, M Boss
Postgraduate medical journal 1978
Trijodthyronin, Reverse-Trijodthyronin, Thyroxin, Trijodthyroninbindung und proteingebundenes Jod in Fl�ssigkeiten von Strumapseudozysten
G Galvan, C Balcke, H Fitz, F Maier
Klinische Wochenschrift 1978
Klinik der inneren Sekretion
A Labhart
1978
Thyroid Function Tests 1978
P CliftonBligh
The Medical Journal of Australia 1978
Thyroid Dysfunction in Chronic Renal Failure A STUDY OF THE PITUITARY-THYROID AXIS AND PERIPHERAL TURNOVER KINETICS OF THYROXINE AND TRIIODOTHYRONINE
VS Lim, VS Fang, AI Katz, S Refetoff
Journal of Clinical Investigation 1977
Concentration of l-Thyroxine and l-Triiodothyronine Specifically Bound to Nuclear Receptors in Rat Liver and Kidney QUANTITATIVE EVIDENCE FAVORING A MAJOR ROLE OF T3 IN THYROID HORMONE ACTION
MI Surks, JH Oppenheimer
Journal of Clinical Investigation 1977
Thyroid Hormonelike Actions of 3,3′,5′-l-Triiodothyronine and 3,3′-Diiodothyronine
SS Papavasiliou, JA Martial, KR Latham, JD Baxter
Journal of Clinical Investigation 1977
THE ACTION OF THYROID HORMONE
J Bernal, S Refetoff
Clinical Endocrinology 1977
Studies on Replacement and Suppressive Dosages of l-Thyroxine
G Nilsson, U Pettersson, K Levin, R Hughes
Acta Medica Scandinavica 1977
T3 TOXICOSIS IN CHILDREN
PC Harland, RG McARTHUR, DM Fawcett
Acta Paediatrica 1977
Reverse triiodothyronine in the chicken
BN Premachandra, S Lang, JA Andrada, JH Kite
Life Sciences 1977
Use of thyroxine- and triiodothyronine-specific antibodies to study thyroxine kinetics in rainbow trout, Salmo gairdneri
JG Eales
General and Comparative Endocrinology 1977
Reassessment of the daily dose of oral thyroxine for replacement therapy in hypothyroid children
I Rezvani, AM DiGeorge
The Journal of Pediatrics 1977
Evaluation of sodium l-thyroxine (T4) requirement in replacement therapy of hypothyroidism
V Abbassi, C Aldige
The Journal of Pediatrics 1977
Thyroid hormone actions and membrane fluidity Blocking action thyroxine on triiodothyronine effect
DD Mendoza, H Moreno, EM Massa, RD Morero, RN Farías
FEBS Letters 1977
In vivo determination of thyroxine deiodination rate in rainbow trout, Salmo gairdneri Richardson
JG Eales
General and Comparative Endocrinology 1977
Circulating reverse triiodothyronine (rT3) in the dog
BN Premachandra, S Lang
Life Sciences 1977
Thyroid Hormone Action: The Mitochondrial Pathway
K Sterling, PO Milch, MA Brenner, JH Lazarus
Science 1977
Metabolism of thyroid hormones by cultured monkey hepatocarcinoma cells. Nonphenolic ring dieodination and sulfation
K Sorimachi, J Robbins
The Journal of biological chemistry 1977
An assessment of daily production and significance of thyroidal secretion of 3, 3', 5'-triiodothyronine (reverse T3) in man
IJ Chopra
Journal of Clinical Investigation 1976
Streptokinase Treatment of Deep Venous Thrombosis of the Lower Extremity
E Johansson, K Ericson, S Zetterquist
Acta Medica Scandinavica 1976
THE RADIOIMMUNOASSAY OF 3,3‘,5’-TRHODOTHYRONINE (REVERSE T3) IN UNEXTRACTED HUMAN SERUM
WA Ratcliffe, J Marshall, JG Ratcliffe
Clinical Endocrinology 1976
Blood Levels of 3,5,3‘-Triiodothyronine and Thyroxine: Differences between Children, Adults, and Elderly Subjects
U Westgren, A Burger, S Ingemansson, A Melander, S Tibblin, E Wåhlin
Acta Medica Scandinavica 1976
LITHIUM, HYPERCALCÆMIA, AND HYPERPARATHYROIDISM
TA Christensson
The Lancet 1976
NUTRITIONAL STATUS AND THYROID HORMONES
SO Olusi, H Mcfarlane, D Orrell, RA Elegbe
The Lancet 1976
Triiodothyronine and thyroxine interrelationships in health and disease
PG Walfish
Canadian Medical Association journal 1976
The uptake and distribution of radiolabelled thyroxine by isolated cardiac myocytes
AH Burns, WJ Reddy
Life Sciences 1976
Comparative clinical pharmacology of thyroid hormones
HA Selenkow, LI Rose
Pharmacology & Therapeutics Part C Clinical Pharmacology and Therapeutics 1976
Myxedema coma
JT Nicoloff
Pharmacology & Therapeutics Part C Clinical Pharmacology and Therapeutics 1976
Peripheral distribution and metabolism of the thyroid hormones: A primarily quantitative assessment
JJ DiStefano, DA Fisher
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology 1976
Analytical Profiles of Drug Substances
A Post, RJ Warren
Analytical Profiles of Drug Substances 1976
Studies on the deiodination of thyroid hormones in Xenopus laevis tadpoles
H Robinson, VA Galton
General and Comparative Endocrinology 1976
Inherited Hypothyroidism
IM Jackson
Clinics in Perinatology 1976
Reduction in extrathyroidal triiodothyronine production by propylthiouracil in man
M Saberi, FH Sterling, RD Utiger
Journal of Clinical Investigation 1975
Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man
DL Geffner, M Azukizawa, JM Hershman
Journal of Clinical Investigation 1975
Estimation of thyroxine and triiodothyronine distribution and of the conversion rate of thyroxine to triiodothyronine in man
M Inada, K Kasagi, S Kurata, Y Kazama, H Takayama, K Torizuka, M Fukase, T Soma
Journal of Clinical Investigation 1975
Reduced peripheral conversion of thyroxine to triiodothyronine in patients with hepatic cirrhosis
S Nomura, CS Pittman, JB Chambers, MW Buck, T Shimizu
Journal of Clinical Investigation 1975
THE THYROID IN ULCERATIVE COLITIS AND CROHN'S DISEASE
G Järnerot, SC Truelove, GT Warner
Acta Medica Scandinavica 1975
SERUM TRIIODOTHYRONINE AND REVERSE TRIIODOTHYRONINE CONCENTRATIONS AFTER SURGICAL OPERATION
WA Burr, EG Black, RS Griffiths, R Hoffenberg, H Meinhold, KW Wenzel
The Lancet 1975
Radioimmunoassay of 3,3′,5′-Triiodo-L-thyronine (Reverse T3) in Human Serum and its Application in Different Thyroid States
H Meinhold, KW Wenzel, P Schürnbrand
Clinical Chemistry and Laboratory Medicine 1975
Production and storage of [125I] thyroxine and [125I] triiodothyronine of high specific activity
JM Kjeld, SF Kuku, L Diamant, TR Fraser, GF Joplin, K Mashiter
Clinica Chimica Acta 1975
Thyroid Hormone Therapy
S Refetoff
Medical Clinics of North America 1975
Tests of Thyroid Function
PR Larsen
Medical Clinics of North America 1975
The Peripheral Action of the Thyroid Hormones
JH Oppenheimer, MI Surks
Medical Clinics of North America 1975
92. Kongreß der Deutschen Gesellschaft für Chirurgie, München, 7.–10. Mai 1975
F Linder, HG Borst, W Brendel, FW Eigler, W Isselhard, F Largiadèr, J Schmier, L Schweiberer, M Turina, E Wolner
1975
The radioimmunoassay of triiodothyronine and its clinical application
CJ Eastman, JM Corcoran, RP Ekins, ES Williams, JD Nabarro
Journal of clinical pathology 1975
TRIIODOTHYRONINE/REVERSE-TRIIODOTHYRONINE BALANCE AND THYROXINE METABOLISM
KW Wenzel, H Meinhold
Lancet 1975
Effects of thyroid hormones on enzymes involved in fatty acid and glycerolipid synthesis
DA Roncari, VK Murthy
The Journal of biological chemistry 1975
Conversion of thyroxine into tri-iodothyronine by rat liver homogenate.
Biochemical Journal 1975
Limited Binding Capacity Sites for l-Triiodothyronine in Rat Liver Nuclei NUCLEAR-CYTOPLASMIC INTERRELATION, BINDING CONSTANTS, AND CROSS-REACTIVITY WITH l-THYROXINE
JH Oppenheimer, HL Schwartz, D Koerner, MI Surks
Journal of Clinical Investigation 1974
A Radioimmunoassay for Measurement of 3,3′, 5′-Triiodothyronine (Reverse T3)
IJ Chopra
Journal of Clinical Investigation 1974
On the mechanism of action of thyroxin, an amino acid analog of tyrosine
MB Dratman
Journal of Theoretical Biology 1974
Incorporation of Radioiodine in Thyroid Hormones for the Determination of T<sub>3</sub>/T<sub>4</sub> Ratio Using Paper Chromatography
YM Megahed, MF Abdel-Wahab, AA Ismai, AA Abdel-Hafiz
Isotopenpraxis Isotopes in Environmental and Health Studies 1974
Suppressive therapy of nontoxic goiter
K Shimaoka, JE Sokal
The American Journal of Medicine 1974
Production of triiodothyronine in normal human subjects and in patients with hyperthyroidism
B Rapoport, SH Ingbar
The American Journal of Medicine 1974
Replacement Dosage of L-Thyroxine in Hypothyroidism: A Re-Evaluation
JM Stock, MI Surks, JH Oppenheimer
New England Journal of Medicine 1974
Diurnal rhythms of thyroid function in chicks
WS Newcomer
General and Comparative Endocrinology 1974
Síndrome de Kocher-Debré-Semelaigne
J Fortes-Rego
Arquivos de Neuro-Psiquiatria 1974
The Assay of Urinary Thyroid Hormones for Assessing Thyroid Function
V Chan
Annals of Clinical Biochemistry 1974
Modulation of Pituitary Responsiveness to Throtropin-Releasing Hormone by Triiodothyronine
L Shenkman, T Mitsuma, CS Hollander
Journal of Clinical Investigation 1973
Control of Thyroid Hormone Secretion in Normal Subjects Receiving Iodides
AG Vagenakis, P Downs, LE Braverman, A Burger, SH Ingbar
Journal of Clinical Investigation 1973
Determination of Iodothyronine Absorption and Conversion of L-Thyroxine (T4) to L-Triiodothyronine (T3) using Turnover Rate Techniques
MI Surks, AR Schadlow, JM Stock, JH Oppenheimer
Journal of Clinical Investigation 1973
Effects of Replacement Doses of Sodium-L-Thyroxine on the Peripheral Metabolism of Thyroxine and Triiodothyronine in Man
LE Braverman, A Vagenakis, P Downs, AE Foster, K Sterling, SH Ingbar
Journal of Clinical Investigation 1973
Triiodothyronine and Thyroxine in the Serum and Thyroid Glands of Iodine-Deficient Rats
GM Abrams, PR Larsen
Journal of Clinical Investigation 1973
CONGENITAL EUTHYROID GOITRE AND PARTIAL PERIPHERAL RESISTANCE TO THYROID HORMONES
BA Lamberg
The Lancet 1973
TRIIODOTHYRONINE
R Hoffenberg
Clinical Endocrinology 1973
INTERACTION OF DRUGS WITH THYROID HORMONE BINDING SITES
JH Oppenheimer
Annals of the New York Academy of Sciences 1973
Serum thyroxine levels in patients receiving L-thyroxine suppression or replacement therapy
A Kahn
Canadian Medical Association journal 1973
Treatment of hypothyroidism: a reappraisal of thyroxine therapy
D Evered, ET Young, BJ Ormston, R Menzies, PA Smith, R Hall
British medical journal 1973
Thyroid hormone action in cell culture: domonstration of nuclear receptors in intact cells and isolated nuclei
HH Samuels, JS Tsai
Proceedings of the National Academy of Sciences 1973
Radioassay and the thyroid gland
J Robbins
Metabolism 1973
Triiodothyronine in cord serum
JM Lieblich, RD Utiger
The Journal of Pediatrics 1973
Thyroid Hormone Action: A Cell-Culture System Responsive to Physiological Concentrations of Thyroid Hormones
HH Samuels, JS Tsai, R Cintron
Science 1973
Double-isotope derivative assay of serum iodothyronines
GA Hagen, LI Diuguid, B Kliman, JB Stanbury
Biochemical Medicine 1973
Evolving Concepts of Thyroid Function
DG Bartuska, MB Dratman
Medical Clinics of North America 1973
Triiodothyronine Hyperthyroidism
H Gharib, HW Wahner
Postgraduate Medicine 1973
Conversion of Thyroxine to Triiodothyronine by Cultured Human Cells
K Sterling, MA Brenner, VF Saldanha
Science 1973
Triiodothyronine Radioimmunoassay
J Lieblich, RD Utiger
Journal of Clinical Investigation 1972
Direct immunoassay of triiodothyronine in human serum
PR Larsen
Journal of Clinical Investigation 1972
Propylthiouracil inhibits the conversion of l-thyroxine to l-triiodothyronine An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone
JH Oppenheimer, HL Schwartz, MI Surks
Journal of Clinical Investigation 1972
Slow fractional removal of nonextractable iodine from rat tissue after injection of labeled l-thyroxine and 3,5,3′-triiodo-l-thyronine A possible clue to the mechanism of initiation and persistence of hormonal action
JH Oppenheimer, MI Surks, HL Schwartz
Journal of Clinical Investigation 1972
A New Radioimmunoassay for Plasma l-Triiodothyronine: Measurements in Thyroid Disease and in Patients Maintained on Hormonal Replacement
MI Surks, AR Schadlow, JH Oppenheimer
Journal of Clinical Investigation 1972
URINARY TRI-IODOTHYRONINE EXCRETION AS INDEX OF THYROID FUNCTION
V Chan, J Landon, GM Besser, RP Ekins
The Lancet 1972
Triiodothyronine: Review of recent studies of its physiology and pathophysiology in man
PR Larsen
Metabolism 1972
Thyroid Function in Pregnancy and Infancy: Maternal Hypothyroxinemia and Retardation of Progeny
EB Man
Critical Reviews in Clinical Laboratory Sciences 1972
The T4-free thyroxine index as a test of thyroid function of first choice
PJ Howorth, RL Ward
Journal of clinical pathology 1972
Specific Triiodothyronine Binding Sites in the Anterior Pituitary of the Rat
AR Schadlow, MI Surks, HL Schwartz, JH Oppenheimer
Science 1972
Triiodothyronine: The 3′-Iodine Is Proximal to the α-Ring in Crystal Structure Conformation
N Camerman, A Camerman
Science 1972
Quantitation of extrathyroidal conversion of l-thyroxine to 3,5,3′-triiodo-l-thyronine in the rat
HL Schwartz, MI Surks, JH Oppenheimer
Journal of Clinical Investigation 1971
The extrathyroidal conversion rate of thyroxine to triiodothyronine in normal man
CS Pittman, JB Chambers, VH Read
Journal of Clinical Investigation 1971
Preparation and Properties of Thyroxine-Binding Alpha Globulin (TBG)
K Sterling, S Hamada, Y Takemura, MA Brenner, ES Newman, M Inada
Journal of Clinical Investigation 1971
Radioimmunassay for measurement of triiodothyronine in human serum
IJ Chopra, DH Solomon, GN Beall
Journal of Clinical Investigation 1971
Serum triiodothyronine: measurements in human serum by radioimmunoassay with corroboration by gas-liquid chromatography
T Mitsuma, N Nihei, MC Gershengorn, CS Hollander
Journal of Clinical Investigation 1971
Red cell sodium in hyperthyroidism
AW Goolden, D Bateman, S Torr
British medical journal 1971
Technical aspects of the estimation of triiodothyronine in human serum: Evidence of conversion of thyroxine to triiodothyronine during assay
PR Larsen
Metabolism 1971
The Importance of Circulating Tri-Iodothyronine
K Sterling
New England Journal of Medicine 1971
Stimulation of mitochondrial protein synthesis and oxygen consumption by thyroxine in vitro without deiodination to triiodothyronine
MP Primack, DF Tapley, J Buchanan
Biochimica et Biophysica Acta (BBA) - General Subjects 1971
Stimulation of iodoproteins and thyroxine formation in human leukocytes by phagocytosis
V Stolc
Biochemical and Biophysical Research Communications 1971
Free Thyroxine and Triiodothyronine
K Sterling
Critical Reviews in Clinical Laboratory Sciences 1971
Current concepts of thyroid physiology
B Rapoport, LJ DeGroot
Seminars in Nuclear Medicine 1971
Thyroxine: Conversion to Triiodothyronine by Isolated Perfused Rat Heart
JL Rabinowitz, ES Hercker
Science 1971
Conversion of Thyroxine to Triiodothyronine in Normal Human Subjects
K Sterling, MA Brenner, ES Newman
Science 1970

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