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Citations to this article

Cholesterol balance and fecal neutral steroid and bile acid excretion in normal men fed dietary fats of different fatty acid composition
William E. Connor, … , Daniel B. Stone, Mark L. Armstrong
William E. Connor, … , Daniel B. Stone, Mark L. Armstrong
Published August 1, 1969
Citation Information: J Clin Invest. 1969;48(8):1363-1375. https://doi.org/10.1172/JCI106102.
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Research Article

Cholesterol balance and fecal neutral steroid and bile acid excretion in normal men fed dietary fats of different fatty acid composition

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Abstract

Six normal men were fed formula diets containing either highly saturated fat (cocoa butter, iodine value 32) or polyunsaturated fat (corn oil, iodine value 125). The sterol balance technique was used to compare the changes in serum cholesterol concentration with the excretion of fecal steroids. The method used for the analysis of fecal steroids was chemical, with a final identification and quantification by gas-liquid chromatography. It was confirmed that the chemical method for fecal steroid analysis was accurate and reproducible.

Authors

William E. Connor, Donald T. Witiak, Daniel B. Stone, Mark L. Armstrong

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Journal of Clinical Investigation 1979
Swine in atherosclerosis research
WH Cevallos, WL Holmes, RN Myers, RD Smink
Atherosclerosis 1979
Sterol balance in abetalipoproteinemia: Studies in a patient with homozygous familial hypobetalipoproteinemia
DR Illingworth, WE Connor, NR Buist, BM Jhaveri, DS Lin, MP McMurry
Metabolism 1979
The cholesterol turnover, synthesis, and absorption in two sisters with familial hypercholesterolemia (type IIa)
GA Carter, WE Connor, AK Bhattacharyya, DS Lin
Journal of lipid research 1979
A study of healthy middle-aged men Effect of unsaturated fats and cholesterol on serum and fecal lipids
P Hill, B Reddy, E Wynder
Journal of the American Dietetic Association 1979
Influence of diets high and low in animal fat on bowel habit, gastrointestinal transit time, fecal microflora, bile acid, and fat excretion
JH Cummings, HS Wiggins, DJ Jenkins, H Houston, T Jivraj, BS Drasar, MJ Hill
Journal of Clinical Investigation 1978
Effects of Dietary Polyunsaturated and Saturated Fat on the Properties of High Density Lipoproteins and the Metabolism of Apolipoprotein A-I
J Shepherd, CJ Packard, JR Patsch, AM Gotto, OD Taunton
Journal of Clinical Investigation 1978
Sterol balance in a patient with abetalipoproteinaemia
NB Myant, D Reichl, JK Lloyd
Atherosclerosis 1978
Plasma apoprotein and lipoprotein lipid levels in vegetarians
J Burslem, G Schonfeld, MA Howald, SW Weidman, JP Miller
Metabolism 1978
Effects of saturated and unsaturated fats given with and without dietary cholesterol on hepatic cholesterol synthesis and hepatic lipid metabolism
W Bochenek, JB Rodgers
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1978
Nutritional and Drug Interrelations
CH Halsted
Nutritional and Drug Interrelations 1978
The role of dietary polyunsaturated fat in lowering blood cholesterol in man
RL Jackson, OD Taunton, JD Morrisett, AM Gotto
Circulation research 1978
Preparation of [24,25-3H] cholesterol. Oxidation in man as a measure of bile acid formation
RS Rosenfeld, HL Bradlow, J Levin, B Zumoff
Journal of lipid research 1978
The steroids of 2000-year-old human coprolites
DS Lin, WE Connor, LK Napton, RF Heizer
Journal of lipid research 1978
Effect of different dietary triglycerides on 7alpha-hydroxylation of cholesterol and other mixed-function oxidations
I Björkhem, R Blomstrand, L Svensson
Journal of lipid research 1978
The Interaction of Dietary Fibers and Cholesterol upon the Plasma Lipids and Lipoproteins, Sterol Balance, and Bowel Function in Human Subjects
TL Raymond, WE Connor, DS Lin, S Warner, MM Fry, SL Connor
Journal of Clinical Investigation 1977
Cholesterol metabolism in Papua New Guineans
M Whyte, P Nestel, AL MacGREGOR
European Journal of Clinical Investigation 1977
Polyunsaturated fat, cholesterol and large bowel tumorigenesis
SA Broitman, JJ Vitale, E Vavrousek-Jakuba, LS Gottlieb
Cancer 1977
Atherosclerosis: Metabolic, Morphologic, and Clinical Aspects
GW Manning, MD Haust
Atherosclerosis 1977
Effect of Deoxycholic Acid Ingestion on Bile Acid Metabolism and Biliary Lipid Secretion in Normal Subjects
NF LaRusso, PA Szczepanik, AF Hofmann
Gastroenterology 1977
Diet and Bile Acid Metabolism
TS Low-Beer
1977
Effect of dietary polyunsaturated pork on plasma lipids and sterol excretion in man
PJ Nestel, Y Homma, TW Scott, LJ Cook, N Havenstein
Lipids 1976
Relationships between plasma lipoprotein cholesterol concentrations and the pool size and metabolism of cholesterol in man
NE Miller, PJ Nestel, P Clifton-Bligh
Atherosclerosis 1976
Effect of dietary fat on cholesterol turnover in old and new world monkeys
JE Corey, RJ Nicolosi, KC Hayes
Experimental and Molecular Pathology 1976
Fettstoffwechsel
G Assmann, J Augustin, E Baraona, HU Benz, W Brech, WV Brown, RJ Desnick, WR Fallat, S Ford, D Fredrickson, CJ Glueck, H Greten, K Harzer, P Herbert, GM Kostner, W Krivit, RI Levy, CS Lieber, M Liersch, G Middelhoff, GL Mills, NB Myant, RF ODea, J Papenberg, H Pilz, HM Rauen, S Sailer, G Schettler, G Schlierf, H Schriewer, D Seidel, J Slack, E Stange, O Stein, Y Stein, D Steinberg, A Weizel, H Wieland
1976
Atherosclerosis Drug Discovery
CE Day
1976
The Cholesterol Problem, the Egg and Lipid Metabolism in the Laying Hen
EC Naber
Poultry science 1976
Effects of polyunsaturated fats on lipid metabolism in patients with hypertriglyceridemia
SM Grundy
Journal of Clinical Investigation 1975
Failure to demonstrate degradation of [4-14C] cholesterol to volatile hydrocarbons in rats and in human fecal homogenates
MD Levitt, RF Hanson, JH Bond, RR Engel
Lipids 1975
Altered bile acid metabolism in vegetarians
GW Hepner
The American Journal of Digestive Diseases 1975
Contrasting Effects on Plasma Lipoproteins of Intravenous Versus Oral Administration of a Triglyceride-Phospholipid Emulsion
GR Thompson, R Segura, H Hoff, AM Gotto
European Journal of Clinical Investigation 1975
The influence of some dietary factors on cholesterol metabolism
NB Myant
Proceedings of the Nutrition Society 1975
Increased sterol excretion with polyunsaturated-fat high-cholesterol diets
PJ Nestel, N Havenstein, Y Homma, TW Scott, LJ Cook
Metabolism 1975
Cholesterol metabolism in hypertriglyceridaemia and the effects of treatment
LA Simons, NB Myant
Clinica Chimica Acta 1975
A modified assay of total faecal bile acid excretion for clinical studies
CB Campbell, WE McIvor
Pathology 1975
Hypolipidemic Agents
D Kritchevsky
1975
Metabolism of Lithocholate in Healthy Man
AE Cowen, MG Κοrman, AF Hofmann, OW Cass, SB Coffin
Gastroenterology 1975
Evaluation of chromic oxide, glycerol triether, and β-sitosterol as fecal flow markers in two species of nonhuman primates
RW Clair, ND Lehner, TE Hamm
Lipids 1975
Gallefluß und Gallensäurenausscheidung bei fettreich ernährten Ratten in Abhängigkeit vom Fettsäurenmuster der Nahrung und von zusätzlich applizierter Cholsäure
D Mayer, G Mayer
Zeitschrift für Ernährungswissenschaft 1974
Cholesterol and bile acid turnover in miniature swine
J Dupont, SY Oh, L O'Deen, MA McClellan, WV Lumb, AB Butterfield, DJ Clow
Lipids 1974
Differences in Bile Acid Excretion in Subjects with Hypercholesterolaemia, Hypertriglyceridaemia and Overweight
PJ Nestel, JD Hunter
Australian and New Zealand Journal of Medicine 1974
Effect of diet on hepatic and intestinal lipogenesis in squirrel, Cebus, and cynomolgus monkeys
JE Corey, KC Hayes
Atherosclerosis 1974
Comparative lipid response of four primate species to dietary changes in fat and carbohydrate
JE Corey, KC Hayes, B Dorr, DM Hegsted
Atherosclerosis 1974
Polyunsaturated Ruminant Fats and Cholesterol Metabolism in Man
PJ Nestel, N Havenstein, TW Scott, LJ Cook
Australian and New Zealand Journal of Medicine 1974
The Different Effects on the Serum Lipids and Fecal Steroids of High Carbohydrate Diets Given Orally or Intravenously
L DenBesten, RH Reyna, WE Connor, LD Stegink
Journal of Clinical Investigation 1973
Cholesterol Metabolism in Human Obesity
PJ Nestel, PH Schreibman, EH Ahrens
Journal of Clinical Investigation 1973
Fat nutrition and diet in childhood
WK Schubert
The American Journal of Cardiology 1973
Lowering of Plasma Cholesterol and Enhanced Sterol Excretion with the Consumption of Polyunsaturated Ruminant Fats
PJ Nestel, N Havenstein, HM Whyte, TJ Scott, LJ Cook
New England Journal of Medicine 1973
Physiology of Bile Acids in the Ileum and Colon
MA Eastwood
Scottish Medical Journal 1973
The Bile Acids, Chemistry, Physiology, and Metabolism
PP Nair, D Kritchevsky
1973
Primate Biliary Physiology
RN Redinger, AH Hermann, DM Small
Gastroenterology 1973
Excretion of sterols from the skin of normal and hypercholesterolemic humans Implications for sterol balance studies
AK Bhattacharyya, WE Connor, AA Spector
Journal of Clinical Investigation 1972
Mechanisms of Lithogenic Bile Formation in American Indian Women with Cholesterol Gallstones
SM Grundy, AL Metzger, RD Adler
Journal of Clinical Investigation 1972
Dietary Factors Affecting Biliary Lipid Secretion in the Rhesus Monkey A Mechanism for the Hypocholesterolaemic Action of Polyunsaturated Fat?
CB Campbell, DJ Cowley, RH Dowling
European Journal of Clinical Investigation 1972
Comparison of isotopic and chromatographic methods for estimating fecal bile acids
BJ Kudchodkar, HS Sodhi, L Horlick
Clinica Chimica Acta 1972
Effect of cholestyramine on composition of duodenal bile in obese human subjects
PD Wood, R Shioda, DL Estrich, SD Splitter
Metabolism 1972
Lack of degradation of dietary and endogenous sterols in gastrointestinal tract of man
BJ Kudchodkar, HS Sodhi, L Horlick
Metabolism 1972
Cholesterol turnover, synthesis, and retention in hypercholesterolemic growing swine
A Marsh, DN Kim, KT Lee, JM Reiner, WA Thomas
Journal of lipid research 1972
Low-density lipoproteins
B Lewis
Biochemical Journal 1971
Dietary Therapy and Prophylaxis of Vascular Disease in Diabetics
MJ Albrink, PC Davidson
Medical Clinics of North America 1971
Cholesterol Production in Obesity
TA Miettinen
Circulation 1971
Reduction and esterification of cholesterol and sitosterol by homogenates of feces
R Rosenfeld, L Hellman
Journal of lipid research 1971
The effects of unsaturated dietary fats on absorption, excretion, synthesis, and distribution of cholesterol in man
SM Grundy, EH Ahrens
Journal of Clinical Investigation 1970
Incubation of human fecal homogenates with 4-14C-cholesterol
PD Wood, D Hatoff
Lipids 1970
Regulation of Cholesterol Metabolism
JM Dietschy, JD Wilson
New England Journal of Medicine 1970
Effect of unsaturated dietary fat on plasma lipoprotein lipase activity in normal and hyperlipidemic states
JD Bagdade, WR Hazzard, J Carlin
Metabolism 1970
Effect of cellulose in the diet on the recovery of dietary plant sterols from the feces
L Denbesten, WE Connor, TH Kent, D Lin
Journal of lipid research 1970
Advances in Lipid Research
AM Scanu
Advances in Lipid Research 1965

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