Citations to this article

Distribution and turnover of cholesterol in humans
Paul J. Nestel, … , H. Malcolm Whyte, DeWitt S. Goodman
Paul J. Nestel, … , H. Malcolm Whyte, DeWitt S. Goodman
Published June 1, 1969
Citation Information: J Clin Invest. 1969;48(6):982-991. https://doi.org/10.1172/JCI106079.
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Distribution and turnover of cholesterol in humans

Abstract

The relationships between some parameters of cholesterol metabolism and body weight were studied in 22 subjects. Cholesterol-4-14C, complexed with plasma lipoprotein, was injected intravenously and from the resultant specific activity-time curves a number of indexes of cholesterol turnover were calculated. These were based on the two-pool model previously described by Goodman and Noble and included estimates of the sizes of the two pools, the production rate of cholesterol in the system, the rate constants for cholesterol removal from the two pools and transfer between the pools, and the metabolic clearance of cholesterol.

Authors

Paul J. Nestel, H. Malcolm Whyte, DeWitt S. Goodman

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Citations to this article in year 2012 (1)

Title and authors Publication Year
Measurement of Reverse Cholesterol Transport Pathways in Humans: In Vivo Rates of Free Cholesterol Efflux, Esterification, and Excretion
S Turner, J Voogt, M Davidson, A Glass, S Killion, J Decaris, H Mohammed, K Minehira, D Boban, E Murphy, J Luchoomun, M Awada, R Neese, M Hellerstein 		Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease 2012

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