Citations to this article

Diagnostic and genetic studies on fibrin-stabilizing factor with a new assay based on amine incorporation
L. Lorand, … , J. W. C. de Kiewiet, H. L. Nossel
L. Lorand, … , J. W. C. de Kiewiet, H. L. Nossel
Published June 1, 1969
Citation Information: J Clin Invest. 1969;48(6):1054-1064. https://doi.org/10.1172/JCI106061.
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Research Article

Diagnostic and genetic studies on fibrin-stabilizing factor with a new assay based on amine incorporation

Abstract

Fibrinoligase, the fibrin cross-linking enzyme, transiently appearing during the course of coagulation in normal blood, was shown to catalyze the incorporation of a fluorescent amine, monodansylcadaverine [or N-(5-aminopentyl)-5-dimethylamino-1-naphthalene-sulfonamide] into casein. The reaction provided the basis of a sensitive fluorimetric method for measuring the activity of the enzyme (and also of similar other transpeptidases, such as transglutaminase).

Authors

L. Lorand, T. Urayama, J. W. C. de Kiewiet, H. L. Nossel

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Citations to this article (142)

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Human plasma fibrinogen heterogeneity: evidence for an extended carboxyl-terminal sequence in a normal gamma chain variant (gamma')
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The human fibrin-stabilizing factors
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Annotation: FACTOR XIII
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FACTOR XIII
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FACTOR XIII (FIBRIN STABILISING FACTOR) IN HENOCH-SCHÖNLEIN'S PURPURA
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Defibrination syndrome as drastic deviation of coagulation and fibrinolysis balance and its therapeutic management
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A physical standard of fibrinogen: Measurement of the elastic modulus of dilute fibrin gels with a new elastometer
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Comparison of the physicochemical properties of fragment D derivatives of fibrinogen and fragment D-D of cross-linked fibrin
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Alternative Pathways for the Activation of Factor XIII
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Factor XIII in a Clinical Material
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FIBRINOLIGASE: THE FIBRIN-STABILIZING FACTOR SYSTEM OF BLOOD PLASMA
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DOCUMENTATION OF THE PLASMA FACTOR XIII DEFICIENCY IN MAN
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TRANSFUSION THERAPY IN CONGENITAL DEFICIENCIES OF PLASMA FACTOR XIII
E Ikkala 		Annals of the New York Academy of Sciences 1972
Factor XIII from human platelets: Effect on fibrin crosslinking
J McDonagh, RP McDonagh 		Thrombosis Research 1972
A filter paper assay for transamidating enzymes using radioactive amine substrates
L Lorand, LK Campbell-Wilkes, L Cooperstein 		Analytical Biochemistry 1972
Fibrinogen and Fibrin-Stabilizing Factor
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Gemetoc aspects of Factor XIII deficiency
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EF Mammen 		Thrombosis and Bleeding Disorders 1971
Factor XIII Assay by an Isotope Method
A Dvilansky, AF Britten, AG Loewy 		British Journal of Haematology 1970
Inheritance of deficiency of fibrin-stabilizing factor (factor 13)
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Blut und Blutkrankheiten
L Heilmeyer, K Betke, KG von Boroviczény, D Busch, E Grundmann, H Heimpel, G Hoffmann, W Hunstein, W Keiderling, M Matthes, H Merker, W Müller, P Pfannenstiel 		1968
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