The pattern of lipid loss from the membrane of red cells incubated in serum is influenced by the availability of glucose. Under homeostatic conditions with respect to glucose, cholesterol alone is lost. This results from esterification of free cholesterol in serum by the serum enzyme, lecithin:cholesterol acyltransferase, and is associated with a proportional decrease in membrane surface area, reflected by an increased osmotic fragility. This selective loss of membrane cholesterol also occurs in hereditary spherocytosis (HS) red cells, even after incubation for 65 hr in the presence of glucose. The loss of free cholesterol from red cells relative to its loss from serum, under these conditions, is greatest at higher hematocrits, similar to those found in the spleen.
Richard A. Cooper, James H. Jandl
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Transfusion | 2006 |
Hereditary Spectrin Deficiency in Golden Retriever Dogs
RJ Slappendel, R Zwieten, M Leeuwen, CT Schneijdenberg |
Journal of Veterinary Internal Medicine | 2005 |
Boston city hospital and the thorndike memorial laboratory: the birth of modern haematology
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British Journal of Haematology | 2003 |
Splenectomy prolongs in vivo survival of erythrocytes differently in spectrin/ankyrin- and band 3–deficient hereditary spherocytosis
R Reliene, M Mariani, A Zanella, WH Reinhart, ML Ribeiro, EM del Giudice, S Perrotta, A Iolascon, S Eber, HU Lutz |
Blood | 2002 |
Hereditary spherocytosis: a review of the clinical and molecular aspects of the disease
H Hassoun, J Palek |
Blood Reviews | 1996 |
Studies in Red Blood Cell Preservation 10.51Cr Recovery of Red Cells after Liquid Storage in a Glycerol-Containing Additive Solution
TJ Greenwalt, UJ Dumaswala, N Rugg |
Vox Sanguinis | 1996 |
Plasma cholesterol ester transfer protein and distribution of cell cholesterol among plasma lipoproteins in vitro in distance runners and sedentary men
WH Sutherland, SA Stapely, MC Robertson, ER Nye |
Clinical Physiology | 1993 |
Studies in Red Blood Cell Preservation
UJ Dumaswala, TL Petrosky, TJ Greenwalt |
Vox Sanguinis | 1992 |
Studies in Red Blood Cell Preservation 2. Comparison of Vesicle Formation, Morphology, and Membrane Lipids during Storage in AS-1 and CPDA-1
TJ Greenwalt, CZ Sostok, UJ Dumaswala |
Vox Sanguinis | 1990 |
Reticulocyte crisis after splenectomy: Evidence for delayed red cell maturation?
LD Haan, JM Werre, AM Ruben, AH Huls, J Gier, GE Staal |
European Journal of Haematology | 1988 |
Effect of red cell age on vesiculation in vitro
TJ Greenwalt, UJ Dumaswala |
British Journal of Haematology | 1988 |
Osmotic properties of human erythrocytes treated by phospholipase A2 from bee venom
J Vaysse, P Pilardeau, L Gattegno, M Garnier |
British Journal of Haematology | 1987 |
Clinical Disorders of Membrane Transport Processes
TE Andreoli, JF Hoffman, DD Fanestil, SG Schultz |
1987 | |
Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques
E Jucker |
1986 | |
Survival of rabbit and horse erythrocytes in vivo after changing the fatty acyl composition of their phosphatidylcholine
FA Kuypers, EW Easton, R Hoven, T Wensing, B Roelofsen, JA Kamp, LL Deenen |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 1985 |
Hereditary spherocytosis of man. Altered binding of cytoskeletal components to the erythrocyte membrane
JS Hill, WH Sawyer, GJ Howlett, JS Wiley |
Biochemical Journal | 1982 |
Reconstitution of the transferrin receptor in lipid vesicles. Effect of cholesterol on the binding of transferrin
MT Nunez, J Glass |
Biochemistry | 1982 |
Red Cell Fragmentation in the Dog: An Editorial Review
AH Rebar, HB Lewis, DB Denicola, WH Halliwell, GD Boon |
Veterinary pathology | 1981 |
NORMAL FLUIDITY OF RED CELL MEMBRANES IN HEREDITARY SPHEROCYTOSIS
RA Cooper, WH Sawyer, MH Leslie, JS Hill, FM Gill, JS Wiley |
British Journal of Haematology | 1980 |
Membrane Cholesterol Depletion and K+Transport in High and Low Potassium Sheep Red Cells
JE Grey, PK Lauf |
Molecular Membrane Biology | 1980 |
Inherited Disorders of the Red Cell Membrane Skeleton
SE Lux, LC Wolfe |
Pediatric Clinics of North America | 1980 |
Validation of an in Vitro Method for Incorporating Labelled Cholesterol into Human Erythrocytes
MH Gottlieb |
Preparative Biochemistry | 1979 |
New models of cellular control: Membrane cytoskeletons, membrane curvature potential, and possible interactions
FH Kirkpatrick |
Biosystems | 1979 |
Viscosity of lymphocyte plasma membrane in aging mice and its possible relation to serum cholesterol
B Rivnay, A Globerson, M Shinitzky |
Mechanisms of Ageing and Development | 1979 |
A Method for the Increased Extraction of Cholesterol from Human Red Blood Cells by Modified Plasma Lipoprotein
MH Gottlieb |
Preparative Biochemistry | 1978 |
11 Alcohol and the haemopoietic system
RL Cumming, A Goldberg |
Clinics in Endocrinology and Metabolism | 1978 |
Physiology of Membrane Disorders
TE Andreoli, JF Hoffman, DD Fanestil |
1978 | |
Membrane Proteins of Incubated Erythrocytes: Effects of Sulphydryl Inhibition
SS Zail, AK Hoek |
British Journal of Haematology | 1977 |
Chemical synthesis of dinitrodiphenylsulfone derivatives of ethanolamine and serine and its application to the study of neighbor analysis of amino-phospholipids in the erythrocyte membrane
GV Marinetti, R Love |
The Journal of Membrane Biology | 1976 |
The limited depletion of cholesterol from erythrocyte membranes on treatment with incubated plasma
MH Gottlieb |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 1976 |
The effect of incubation in vitro on the susceptibility of monkey erythrocytes to invasion by Plasmodium knowlesi
PI Trigg, PG Shakespeare |
Parasitology | 1976 |
Modification of red cell membrane structure by cholesterol-rich lipid dispersions. A model for the primary spur cell defect
RA Cooper, EC Arner, JS Wiley, SJ Shattil |
Journal of Clinical Investigation | 1975 |
The Red Blood Cell
GJ Brewer |
The Red Blood Cell | 1974 |
Effect of Metabolic State on Immune-Hemolysis of L-Positive Low Potassium (LK) Sheep Red Blood Cells by ISO-Immune Anti-L Serum and Rabbit Serum Complement
PK Lauf, MP Dessent |
Immunological Investigations | 1973 |
Alcohol and the Blood
LE Böttiger |
Scandinavian Journal of Haematology | 1973 |
Loss of Membrane Components in the Pathogenesis of Antibody-Induced Spherocytosis
RA Cooper |
Journal of Clinical Investigation | 1972 |
An Analysis of Lipoproteins, Bile Acids, and Red Cell Membranes Associated with Target Cells and Spur Cells in Patients with Liver Disease
RA Cooper, MD Puray, P Lando, MS Greenverg |
Journal of Clinical Investigation | 1972 |
The Red Cell: A Haematological Odyssey
JC White, JM White |
British Journal of Haematology | 1972 |
Co-ordinated Increase of Sodium Leak and Sodium Pump in Hereditary Spherocytosis
JS Wiley |
British Journal of Haematology | 1972 |
The effect of experimental biliary obstruction on the structure and lipid content 0f rat erythrocytes
S Calandra, MJ Martin, MJ O'shea, N McIntyre |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1972 |
Fetal and Neonatal Disorders
SA Kaplan |
Fetal and Neonatal Disorders | 1972 |
Hemolysis and Changes in Erythrocyte Membrane Lipids
SB Shohet |
New England Journal of Medicine | 1972 |
Effects of plasma lipoproteins from control and cholesterol-fed guinea pigs on red cell morphology and cholesterol content: an in vitro study
C Sardet, H Hansma, R Ostwald |
Journal of lipid research | 1972 |
The Autoxidation of Human Red Cell Lipids Induced by Hydrogen Peroxide
J Stocks, TL Dormandy |
British Journal of Haematology | 1971 |
PLASMA LECITHIN-CHOLESTEROL ACYLTRANSFERASE AND ERYTHROCYTE LIPIDS IN LIVER DISEASE
E Gjone, KR Norum |
Acta Medica Scandinavica | 1970 |
Abnormality of Red-Cell Diameter/Thickness Ratio: Findings in Iron-Deficiency Anaemia
JA Child, WM Bowry, JP Knowles |
British Journal of Haematology | 1970 |
Interactions of red cells with phagocytes of the wax-moth (Galleria mellonella, L.) and mouse
M Rabinovitch, MJ Stefano |
Experimental Cell Research | 1970 |
An unusual variant of hereditary spherocytosis
JS Wiley, BG Firkin |
The American Journal of Medicine | 1970 |
Advances in Lipid Research
AM Scanu |
Advances in Lipid Research | 1965 |