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Citations to this article

Effects of secretin, pancreozymin, or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man
J. Dupre, … , R. W. Waddell, J. C. Beck
J. Dupre, … , R. W. Waddell, J. C. Beck
Published April 1, 1969
Citation Information: J Clin Invest. 1969;48(4):745-757. https://doi.org/10.1172/JCI106032.
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Effects of secretin, pancreozymin, or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man

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Abstract

Intravenous administration of porcine secretin or pancreozymin or synthetic human gastrin II resulted in raised increments in serum immunoreactive insulin during intravenous infusion of glucose in normal man. Enhancement of serum immunoreactive insulin by each hormone was associated with accelerated disposal of glucose. In response to prolonged intravenous infusion of arginine with pancreozymin there was a maintained rise in immunoreactive insulin and glucagon-like immunoreactivity in the blood. These effects of pancreozymin and arginine were not reproduced with secretin and arginine, and may have been due to the stimulation of glucagon secretion together with insulin by pancreozymin.

Authors

J. Dupre, J. D. Curtis, R. H. Unger, R. W. Waddell, J. C. Beck

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Year: 2025 2020 2019 2016 2014 2012 2011 2010 2008 2007 2006 2003 1996 1994 1993 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980 1979 1978 1977 1976 1975 1974 1973 1972 1971 1970 1969 1964 1957 Total
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Citations to this article (140)

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