Citations to this article

Bone Matrix Turnover And Balance In Vitro: I. The effects of parathyroid hormone and thyrocalcitonin
Barry Flanagan, George Nichols Jr.
Barry Flanagan, George Nichols Jr.
Published April 1, 1969
Citation Information: J Clin Invest. 1969;48(4):595-606. https://doi.org/10.1172/JCI106018.
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Bone Matrix Turnover And Balance In Vitro: I. The effects of parathyroid hormone and thyrocalcitonin

Abstract

Labeled proline from incubation media has been shown to be incorporated into living bone matrix collagen in vitro. Hydroxyproline is released from fresh bone slices in similar systems in a characteristic curve against time. This hydroxyproline is derived from three distinct sources, each of which may be separately quantitated. Part of the total represents passive solubilization of matrix collagen, part is derived from new synthesis of soluble collagen occurring in vitro, and the remainder is released by cell-mediated resorptive action.

Authors

Barry Flanagan, George Nichols Jr.

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Total citations by year

Year: 2014 2012 1985 1979 1978 1977 1976 1975 1974 1973 1972 1971 1970 1969 Total
Citations: 1 1 1 1 2 2 4 1 1 5 4 3 2 1 29
Citation information

Citations to this article (29)

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WP Deiss, DL Hern 		Biochimica et Biophysica Acta (BBA) - General Subjects 1979
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J Rø, N Langeland, J Sander 		Acta Orthopaedica 1978
Klinik der inneren Sekretion
A Labhart 		1978
Comparison of effects of parathyroidectomy and ethane-1-hydroxy-1,1-diphosphonate (EHDP) administration upon bone synthesis of hydroxyproline and urinary excretion of hydroxyproline in rats
A Goulding, R McChesney 		Calcified Tissue Research 1977
TheIn VitroEffect of Oestradiol on Collagen Metabolism in Metaphyseal Rat Bone
N Langeland 		Acta Orthopaedica 1977
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E Heidbreder, F L�ke, A Heidland 		Klinische Wochenschrift 1976
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AM Parfitt 		Metabolism 1976
Die Wirkung einer Calcitonin-Langzeittherapie auf Knochenzellen und Knochenmineralisation bei der Ratte
A Schulz, G Delling 		Virchows Archiv A Pathological Anatomy and Histopathology 1976
Kollagenstoffwechsel und Mineralisation des ur�mischen Knochens ? molekularpathologische Aspekte der renalen Osteodystrophie
E Heidbreder, F Lke, A Heidland 		Klinische Wochenschrift 1976
Accumulation of collagen-containing vacuoles in osteoblasts after administration of colchicine
JP Scherft, JN Heersche 		Cell and Tissue Research 1975
Characteristics of calcium uptake by calcitonin-treated mouse calvariain vitro
HH Messer, WD Armstrong, L Singer 		Calcified Tissue Research 1974
Inhibition of Bone Matrix Formation, Mineralization, and Resorption in Thyroparathyroidectomized Rats
J Wergedal, M Stauffer, D Baylink, C Rich 		Journal of Clinical Investigation 1973
Total urinary hydroxyproline excreted in healing experimental rat rickets, studied with14C proline
V Parsons, C Davies, M Self 		Calcified Tissue Research 1973
Quantitative histological measurements of bone turnover in primary hyperparathyroidism
CD Wilde, ZF Jaworski, AR Villanueva, HM Frost 		Calcified Tissue Research 1973
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LV Avioli 		Kidney International 1973
Influence of in vivo-incorporated fluoride on collagen metabolism by mouse calvaria in organ culture
HH Messer, WD Armstrong, L Singer 		Archives of Oral Biology 1973
Effect of Experimental Chronic Renal Insufficiency on Bone Mineral and Collagen Maturation
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Accelerated chromatographic method for determination of hydroxyproline
PX Callahan, JA Shepard, S Ellis 		Analytical Biochemistry 1972
Structure
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G Nichols, B Flanagan, JS der Veer, JW Johnson, CL Hampers, JP Merrill 		Metabolism 1972
Ca-Stoffwechselst�rungen bei chronischer Niereninsuffizienz
E Ritz, HG Sieberth, B Krempien 		Klinische Wochenschrift 1971
Ionic and hormonal control of calcium homeostasis
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W Bargmann, J Kühnau, RE Siebenmann, H Steiner, E Uehlinger, G Seifert 		1971
Cyclic AMP stimulation of amino acid uptake in bone and kidney
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