James D. Lehmann, … , Jack A. Barnett, Jay P. Sanford
Citation Information: J Clin Invest. 1968;47(11):2541-2550. https://doi.org/10.1172/JCI105936.
James D. Lehmann, … , Jack A. Barnett, Jay P. Sanford
Published November 1, 1968
Citation Information: J Clin Invest. 1968;47(11):2541-2550. https://doi.org/10.1172/JCI105936.
Abstract
Experiments using an in vitro method of assessing protein synthesis by 14C amino acid incorporation were designed to determine whether pyelonephritic kidneys were capable of local antibody production. Unilateral pyelonephritis was produced in rabbits by intravenous injection of E. coli 0-75 while one ureter was transiently occluded. The capability of protein and immunoglobulin synthesis by pyelonephritic kidneys, contralateral kidneys, normal kidneys, and spleens from normal and pyelonephritic animals was measured.
Authors
James D. Lehmann, James W. Smith, Thomas E. Miller, Jack A. Barnett, Jay P. Sanford
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