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Effect of sodium taurolithocholate on bile flow and bile acid excretion

Norman B. Javitt, Sidney Emerman

Norman B. Javitt, Sidney Emerman

Published May 1, 1968
Citation Information: J Clin Invest. 1968;47(5):1002-1014. https://doi.org/10.1172/JCI105790.

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Citations to this article (208)

Title and authors	Publication	Year
Monomeric bile acids modulate the ATPase activity of detergent-solubilized ABCB4/MDR3 T Kroll, SH Smits, L Schmitt	Journal of lipid research	2021
The Liver: Biology and Pathobiology IM Arias, HJ Alter, JL Boyer, DE Cohen, DA Shafritz, SS Thorgeirsson, AW Wolkoff		2020
Hepatic bile formation: bile acid transport and water flow into the canalicular conduit NB Javitt	AJP Gastrointestinal and Liver Physiology	2020
Quantitative Kinetic Models from Intravital Microscopy: A Case Study Using Hepatic Transport M Tavakoli, K Tsekouras, R Day, KW Dunn, S Pressé	The Journal of Physical Chemistry B	2019
Sphingosine 1-phosphate receptor 2/adenylyl cyclase/protein kinase A pathway is involved in taurolithocholate-induced internalization of Abcc2 in rats RB Andermatten, N Ciriaci, VS Schuck, ND Siervi, MV Razori, GS Miszczuk, AC Medeot, CA Davio, FA Crocenzi, MG Roma, IR Barosso, EJ Pozzi	Archives of Toxicology	2019
Review article: therapeutic bile acids and the risks for hepatotoxicity K Ashby, EE Almario, W Tong, J Borlak, R Mehta, M Chen	Alimentary Pharmacology & Therapeutics	2018
Inborn Errors of Bile Acid Metabolism JE Heubi, KD Setchell, KE Bove	Clinics in Liver Disease	2018
Possible Role of Phosphatidylcholine and Sphingomyelin on Fumonisin B1-mediated Toxicity Y Yamazoe, N Koyama, S Kumagai	Food Safety	2017
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-elicited effects on bile acid homeostasis: Alterations in biosynthesis, enterohepatic circulation, and microbial metabolism KA Fader, R Nault, C Zhang, K Kumagai, JR Harkema, TR Zacharewski	Scientific Reports	2017
Preparation, optimization, characterization and cytotoxicity in vitro of Baicalin-loaded mixed micelles H Zhai, L Zhao, L Chu, X Han, G Zhai	Journal of Colloid and Interface Science	2014
History of hepatic bile formation: old problems, new approaches NB Javitt	AJP Advances in Physiology Education	2014
Fetal and Neonatal Physiology LH Johnson, VK Bhutani	Fetal and Neonatal Physiology	2011
Pulmonary surfactant: an immunological perspective ZC Chroneos, Z Sever-Chroneos, VL Shepherd	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology	2009
Bile Acid Sulfation: A Pathway of Bile Acid Elimination and Detoxification Y Alnouti	Toxicological Sciences	2009
PKCε-dependent and -independent effects of taurolithocholate on PI3K/PKB pathway and taurocholate uptake in HuH-NTCP cell line CM Schonhoff, A Yamazaki, S Hohenester, CR Webster, B Bouscarel, MS Anwer	AJP Gastrointestinal and Liver Physiology	2009
Store-operated Ca2+ channels and Stromal Interaction Molecule 1 (STIM1) are targets for the actions of bile acids on liver cells EC Aromataris, J Castro, GY Rychkov, GJ Barritt	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	2008
Silibinin prevents cholestasis-associated retrieval of the bile salt export pump, Bsep, in isolated rat hepatocyte couplets: Possible involvement of cAMP FA Crocenzi, CL Basiglio, LM Pérez, MS Portesio, EJ Pozzi, MG Roma	Biochemical Pharmacology	2005
Drug- and chemical-induced cholestasis R Mohi-ud-din, JH Lewis	Clinics in Liver Disease	2004
Impaired localisation and transport function of canalicular Bsep in taurolithocholate induced cholestasis in the rat FA Crocenzi, AD Mottino, EJ Pozzi, JM Pellegrino, EA Garay, P Milkiewicz, M Vore, R Coleman, MG Roma	Gut	2003
Preventive effect of silymarin against taurolithocholate-induced cholestasis in the rat FA Crocenzi, EJ Pozzi, JM Pellegrino, EA Garay, AD Mottino, MG Roma	Biochemical Pharmacology	2003
Taurolithocholic Acid Exerts Cholestatic Effects via Phosphatidylinositol 3-Kinase-dependent Mechanisms in Perfused Rat Livers and Rat Hepatocyte Couplets U Beuers, GU Denk, CJ Soroka, R Wimmer, C Rust, G Paumgartner, JL Boyer	The Journal of biological chemistry	2003
Optimisation of Bile Production during Normothermic Preservation of Porcine Livers CJ Imber, SD st. Peter, IL de Cenarruzabeitia, H Lemonde, M Rees, A Butler, PT Clayton, PJ Friend	American Journal of Transplantation	2002
Hepatoprotection with tauroursodeoxycholate and beta muricholate against taurolithocholate induced cholestasis: involvement of signal transduction pathways P Milkiewicz, MG Roma, E Elias, R Coleman	Gut	2002
25R,26-Hydroxycholesterol revisited: synthesis, metabolism, and biologic roles NB Javitt	Journal of lipid research	2002
Stimulation of ATP secretion in the liver by therapeutic bile acids MH Nathanson, AD Burgstahler, A Masyuk, NF Larusso	Biochemical Journal	2001
Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C G Alvelius, O Hjalmarson, WJ Griffiths, I Björkhem, J Sjövall	Journal of lipid research	2001
Biliary bile acids in primary biliary cirrhosis: effect of ursodeoxycholic acid B Combes, RL Carithers, WC Maddrey, S Munoz, G Garcia-Tsao, GF Bonner, JL Boyer, VA Luketic, ML Shiffman, MG Peters, H White, RK Zetterman, R Risser, SS Rossi, AF Hofmann	Hepatology	1999
DRUG- AND CHEMICAL-INDUCED CHOLESTASIS JH Lewis, HJ Zimmerman	Clinics in Liver Disease	1999
Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes U Beuers, I Probst, C Soroka, JL Boyer, GA Kullak-Ublick, G Paumgartner	Hepatology	1999
Tauroursodeoxycholate and S-adenosyl-L-methionine exert an additive ameliorating effect on taurolithocholate-induced cholestasis: A study in isolated rat hepatocyte couplets P Milkiewicz, CO Mills, MG Roma, J Ahmed-Choudhury, E Elias, R Coleman	Hepatology	1999
BILIARY SECRETION OF EXTRACORPOREAL PORCINE LIVERS WITH SINGLE AND DUAL VESSEL PERFUSION: DP Foley, FJ Vittimberga, SH Quarfordt, SE Donohue, AN Traylor, J MacPhee, T McLaughlin, R Ricciardi, MP Callery, WC Meyers	Transplantation	1999
Bile acid synthesis in the Smith-Lemli-Opitz syndrome: effects of dehydrocholesterols on cholesterol 7α-hydroxylase and 27-hydroxylase activities in rat liver A Honda, G Salen, S Shefer, AK Batta, M Honda, G Xu, GS Tint, Y Matsuzaki, J Shoda, N Tanaka	Journal of lipid research	1999
Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease KD Setchell, M Schwarz, NC O'Connell, EG Lund, DL Davis, R Lathe, HR Thompson, RW Tyson, RJ Sokol, DW Russell	Journal of Clinical Investigation	1998
Urinary 7α-hydroxy-3-oxochol-4-en-24-oic and 3-oxochola-4,6-dien-24-oic acids in infants with cholestasis A Kimura, M Suzuki, T Murai, T Kurosawa, M Tohma, M Sata, T Inoue, A Hoshiyama, E Nakashima, Y Yamashita, T Fujisawa, H Kato	Journal of Hepatology	1998
Differential Interaction of Bile Acids from Patients with Inborn Errors of Bile Acid Synthesis with Hepatocellular Bile Acid Transporters B Stieger, J Zhang, B O'Neill, J Sjovall, PJ Meier	European Journal of Biochemistry	1997
Synthesis, physical and biological properties of lithocholyl-lysyl-fluorescein: a fluorescent monohydroxy bile salt analogue with cholestatic properties1Dr. C.O. Mills Jr. would like to dedicate this paper to his late father, C.O. Mills Sr. who died on 18th November 1996.1 CO Mills, P Milkiewicz, DP Molloy, DJ Baxter, E Elias	Biochimica et Biophysica Acta (BBA) - General Subjects	1997
Monohydroxy bile acid induced cholestasis: role of biotransformation I M Yousef, G Bouchard, B Tuchweber, G L Plaa	Drug Metabolism Reviews	1997
Taurolithocholate can inhibit the biliary discharge of lysosomes in the rat RA Marinelli, JM Pellegrino, MC Larocca	Biochimica et Biophysica Acta (BBA) - General Subjects	1997
Current concepts of hepatic uptake, intracellular transport and biliary secretion of bile acids: Physiological basis and pathophysiological changes in cholestatic liver dysfunction SA Azer, NH Stacey	Journal of Gastroenterology and Hepatology	1996
Effects of ursodeoxycholic acid and chenodeoxycholic acid on major histocompatibility complex class I gene expression F Hirano, H Tanaka, Y Makino, K Okamoto, I Marino	Journal of Gastroenterology	1996
Tauroursodeoxycholate increases rat liver ursodeoxycholate levels and limits lithocholate formation better than ursodeoxycholate CM Rodrigues, BT Kren, CJ Steer, KD Setchell	Gastroenterology	1995
Bile Acids in the Diagnosis, Pathology, and Therapy of Hepatobiliary Disease MS Anwer, DJ Meyer	Veterinary Clinics of North America Small Animal Practice	1995
The urinary bile acid excretion in healthy premature and full-term infants during the neonatal period B Strandvik, E Wahlén, SA Wikström	Scandinavian Journal of Clinical & Laboratory Investigation	1994
Abnormal bile acids in the Smith-Lemli-Opitz syndrome MR Natowicz, JE Evans	American Journal of Medical Genetics	1994
Ursodeoxycholate protects oxidative mitochondrial metabolism from bile acid toxicity: Dose-response study in isolated rat liver mitochondria S Krähenbühl, S Fischer, C Talos, PJ Reichen	Hepatology	1994
Hepatic transport of organic anions in taurolithocholate-induced cholestasis in rats MG Roma, GL Peñalva, RM Agüero, EA Garay	Journal of Hepatology	1994
Phase I and phase II metabolism of lithocholic acid in hepatic acinar zone 3 necrosis S Dionne, B Tuchweber, GL Plaa, IM Yousef	Biochemical Pharmacology	1994
Effect of Epomediol on Taurocholate Uptake in Hepatocytes Isolated from Normal Rats or Rats with Ethinyloestradiol-Induced Cholestasis M Barone, A Azzarone, A Angelini, M Zamparella, P Dell'Aquila, A Francavilla	Pharmacology & Toxicology	1993
Alterations in mitochondrial function and morphology in chronic liver disease: Pathogenesis and potential for therapeutic intervention S Krähenbühl	Pharmacology & Therapeutics	1993
Hepatoprotective properties of ursodeoxycholic acid DM Heuman	Gastroenterology	1993
Lithocholate-3-O-glucuronide-induced cholestasis: A study with congenital hyperbilirubinemic rats and effects of ursodeoxycholate conjugates H Takikawa, K Minagawa, N Sano, M Yamanaka	Digestive Diseases and Sciences	1993
Potentiation of lithocholic-acid-induced cholestasis by methyl isobutyl ketone LD Joseph, IM Yousef, GL Plaa, M Sharkawi	Toxicology Letters	1992
Tight junction permeability and liver plasma membrane fluidity in lithocholate-induced cholestasis DD Vu, B Tuchweber, P Raymond, IM Yousef	Experimental and Molecular Pathology	1992
Pathogenesis of lithocholate-induced intrahepatic cholestasis: Role of glucuronidation and hydroxylation of lithocholate DD Vu, B Tuchweber, GL Plaa, IM Yousef	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1992
Taurolithocholate-induced inhibition of biliary lipid and protein excretion in the rat RA Marinelli, MG Roma, JM Pellegrino, EA Garay	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1992
Bile acid and sterol solubilization in 2-hydroxypropyl-beta-cyclodextrin JD Caprio, J Yun, NB Javitt	Journal of lipid research	1992
Chemical-induced interference with hepatocellular transport. Role in cholestasis V Kukongviriyapan, NH Stacey	Chemico-Biological Interactions	1991
Cholestasis induced by lithocholate and its glucuronide: their biliary excretion and metabolism H Takikawa, H Ohki, N Sano, T Kasama, M Yamanaka	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1991
The effect of bile salts on human vascular endothelial cells CM Garner, CO Mills, E Elias, JM Neuberger	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	1991
Bile acids and bile alcohols in a child with hepatic 3 beta-hydroxy-delta 5-C27-steroid dehydrogenase deficiency: effects of chenodeoxycholic acid treatment H Ichimiya, B Egestad, H Nazer, ES Baginski, PT Clayton, J Sjövall	Journal of lipid research	1991
Tauroursodeoxycholate prevents taurolithocholate-induced cholestasis and toxicity in rat liver J Schölmerich, U Baumgartner, K Miyai, W Gerok	Journal of Hepatology	1990
Neonatal cholestasis: An approach for the practicing pediatrician JE Heubi, CC Daugherty	Current Problems in Pediatrics	1990
Taurohyocholate, taurocholate, and tauroursodeoxycholate but not tauroursocholate and taurodehydrocholate counteract effects of taurolithocholate in rat liver J Schölmerich, S Kitamura, U Baumgartner, K Miyai, W Gerok	Research in Experimental Medicine	1990
Modern Concepts in Gastroenterology Volume 2 E Shaffer, AB Thomson		1989
Ketonic bile acids in urine of infants during the neonatal period E Wahlén, B Egestad, B Strandvik, J Sjoóvall	Journal of lipid research	1989
Delta 4-3-oxosteroid 5 beta-reductase deficiency described in identical twins with neonatal hepatitis. A new inborn error in bile acid synthesis KD Setchell, FJ Suchy, MB Welsh, L Zimmer-Nechemias, J Heubi, WF Balistreri	Journal of Clinical Investigation	1988
The effect of methimazole on bile flow and bile acid secretion in the rat J Ruiz, ME Mun̄oz, A Esteller, J Gonzalez	Biochemical Pharmacology	1988
The Bile Acids: Chemistry, Physiology, and Metabolism KD Setchell, D Kritchevsky, PP Nair		1988
Biopathology of the Liver PM Motta		1988
Familial giant cell hepatitis associated with synthesis of 3 beta, 7 alpha-dihydroxy-and 3 beta,7 alpha, 12 alpha-trihydroxy-5-cholenoic acids PT Clayton, JV Leonard, AM Lawson, KD Setchell, S Andersson, B Egestad, J Sjövall	Journal of Clinical Investigation	1987
Effect of bilirubin and bile acids on biliary phospholipid secretion during bromobenzene-induced hepatic injury in the rabbit J González, ME Muñoz, A Esteller	Experimental Pathology	1987
Biliary lipid secretion in the regenerating liver of the rat F Pérez-Barriocanal, J González, A Esteller	British Journal of Experimental Pathology	1987
Benign recurrent intrahepatic cholestasis GY Minuk, EA Shaffer	Gastroenterology	1987
Membrane Transport Processes in Organized Systems TE Andreoli, JF Hoffman, DD Fanestil, SG Schultz		1987
Cholesterol synthesis in rat liver peroxisomes. Conversion of mevalonic acid to cholesterol SL Thompson, R Burrows, RJ Laub, SK Krisans	The Journal of biological chemistry	1987
Drug-Induced Cholestasis HJ Zimmerman, JH Lewis	Medical Toxicology	1987
Metabolism of 24-norlithocholic acid in the rat: Formation of hydroxyl- and carboxyl-linked glucuronides and effect on bile flow KE Shattuck, A Radominska-Pyrek, P Zimniak, EW Adcock, R Lester, JS Pyrek	Hepatology	1986
Inhibition of hepatic and extrahepatic glutathione S-transferases by primary and secondary bile acids JD Hayes, TJ Mantle	Biochemical Journal	1986
Biliary secretion in the rat after partial hepatectomy F Pérez-Barriocanal, J González, A Esteller	Comparative Biochemistry and Physiology Part A: Physiology	1986
Bile acid synthesis. Metabolism of 3 beta-hydroxy-5-cholenoic acid to chenodeoxycholic acid NB Javitt, E Kok, F Carubbi, T Blizzard, M Gut, CY Byon	The Journal of biological chemistry	1986
Metabolism and cholestatic effect of 3α-hydroxy-7ζ-methyl-5β-cholanoic acid M Une, EH Mosbach, BI Cohen, P May-Donath, CK Mcsherry	Lipids	1985
Taurolithocholate-induced intrahepatic cholestasis: Potentiation by methyl isobutyl ketone and methyl n-butyl ketone in rats GL Plaa, P Ayotte	Toxicology and Applied Pharmacology	1985
The maximal biliary excretory rate (Tm) of ioglycamide in the rat VA Mesa, J Fevery, JD Groote	Journal of Hepatology	1985
Determination of 3β-hydroxy-5-cholenoic acid in serum of hepatobiliary diseases—Its glucuronidated and sulfated conjugates H Takikawa, H Otsuka, T Beppu, Y Seyama	Biochemical Medicine	1985
Heterogeneity of rabbit hepatocytes for bile secretion after acinar zone 3 damage induced by bromobenzene J González, A Esteller	Biochemical Pharmacology	1985
Taurolithocholate increases heme catabolism and alters the clearance of antipyrine in the rat WR Berry, G Kirshenbaum, C Hoilien, M Le, J Reichen	Gastroenterology	1985
Trends in Hepatology L Bianchi, W Gerok, H Popper		1985
Liver, Nutrition, and Bile Acids G Galli, E Bosisio		1985
Bile acid synthesis in rat liver peroxisomes: metabolism of 26-hydroxycholesterol to 3 beta-hydroxy-5-cholenoic acid SK Krisans, SL Thompson, LA Pena, E Kok, NB Javitt	Journal of lipid research	1985
Lithocholate glucuronide is a cholestatic agent DG Oelberg, MV Chari, JM Little, EW Adcock, R Lester	Journal of Clinical Investigation	1984
Urinary excretion of tetrahydroxylated bile acids in children with α1-antitrypsin deficiency and neonatal cholestasis A Németh, B Strandvik	Scandinavian Journal of Clinical & Laboratory Investigation	1984
Urinary concentrations of bile acid glucuronides and sulfates in hepatobiliary diseases H Takikawa, T Beppu, Y Seyama	Gastroenterologia Japonica	1984
Lithocholic acid-cholesterol interactions in rat liver plasma membrane fractions M Yousef, M Lewittes, B Tuchweber, CC Roy, A Weber	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1984
Biliary secretion and hepatic metabolism of taurine-conjugated 7α-hydroxy and 7β-hydroxy bile acids in the dog M Nakagaki, RG Danzinger, AF Hofmann, RA DiPietro	Gastroenterology	1984
Lithocholic acid-induced cholestasis in newborn rats B Tuchweber, A Perea, D Lee, IM Yousef	Toxicology Letters	1983
Changes of the pattern of biliary bile acids during isolated rat liver perfusion J Schoelmerich, S Kitamura, K Miyai	Biochemical and Biophysical Research Communications	1983
Hormonal control of biliary lipid secretion in dogs KI Bickerstaff, CA Garberoglio, AL Baker, AR Moossa	Annals of Surgery	1983
The action of salicylates on bile flow in man MJ Cooper, RC Williamson	British Journal of Clinical Pharmacology	1983
Effects of resection or bypass of the distal ileum on the lithogenicity of bile KI Bickerstaff, AR Moossa	The American Journal of Surgery	1983
Effect of chlorpromazine on hepatic transport of indocyanine green in rats SC Tsao, Y Sawada, T Iga, M Hanano	Biochemical Pharmacology	1983
Chenodeoxycholic acid-3-sulfate C Eng, NB Javitt	Biochemical Pharmacology	1983
Effect of nafcillin on hepatic excretory function C Eng, NB Javitt	Biochemical Pharmacology	1983
Monohydroxy bile salt sulfates: Tauro-3β-hydroxy-5-cholenoate-3-sulfate induces intrahepatic cholestasis in rats U Mathis, G Karlaganis, R Preisig	Gastroenterology	1983
Pediatric Liver Disease MM Fisher, CC Roy		1983
URINARY MONOHYDROXY BILE ACIDS IN YOUNG INFANTS WITH OBSTRUCTIVE JAUNDICE Y Tazawa, T Konno	Acta Paediatrica	1982
Intrahepatic cholestasis as a side-effect of drug therapy G Feuer, MS Dhami	Canadian family physician Médecin de famille canadien	1982
Effect of somatostatin on determinants of bile flow in unanesthetized dogs MH Lewis, AL Baker, E Ipp, AR Moossa	Annals of Surgery	1982
Transcellular transport of fluorescein in hepatocyte monolayers: evidence for functional polarity of cells in culture CA Barth, LR Schwarz	Proceedings of the National Academy of Sciences	1982
Is glucagon a choleretic hormone at physiologic blood levels? CA Garberoglio, KI Bickerstaff, AL Baker, AR Moossa	The American Journal of Surgery	1982
Chenodeoxycholic acid synthesis in the hamster: A metabolic pathway via 3β, 7α-dihydroxy-5-cholen-24-oic acid B Kulkarni, NB Javitt	Steroids	1982
Secretin enhances [14C]erythritol clearance in unanesthetized dogs MH Lewis, AL Baker, J Dhorajiwala, AR Moossa	Digestive Diseases and Sciences	1982
Pathogenetische Bedeutung der Gallensäuren W Gerok, S Matern	Klinische Wochenschrift	1981
1,3-Butanediol pretreatment on the cholestasis induced in rats by manganese-bilirubin combination, taurolithocholic acid, or α-naphthylisothiocyanate E Lamirande, GL Plaa	Toxicology and Applied Pharmacology	1981
Studies on the Enterohepatic Circulation of Bile Acids in Infancy and Childhood O Arisaka	Pediatrics International	1981
Lithocholate cholestasis—Sulfated glycolithocholate-induced intrahepatic cholestasis in rats IM Yousef, B Tuchweber, RJ Vonk, D Massé, M Audet, CC Roy	Gastroenterology	1981
Intrahepatic cholestasis induced by allo monohydroxy bile acid in rats RJ Vonk, B Tuchweber, D Massé, A Perea, M Audet, CC Roy, IM Yousef	Gastroenterology	1981
Separation of sulfated from non-sulfated serum bile acids without the use of Sephadex columns G Lepage, CC Roy, AM Weber	Journal of lipid research	1981
Bile acid synthesis. Metabolism of 3 beta-hydroxy-5-cholenoic acid in the hamster E Kok, S Burstein, NB Javitt, M Gut, CY Byon	The Journal of biological chemistry	1981
Atypische Gallens�uren P Back	Klinische Wochenschrift	1980
Taurolithocholate-induced increase in the intrabiliary pressure generated during retrograde intrabiliary infusion of saline in rats: Antagonism by taurocholate and glycocholate MA Jansen, JR Olson, JM Fujimoto	Toxicology and Applied Pharmacology	1980
Ergebnisse der Inneren Medizin und Kinderheilkunde / Advances in Internal Medicine and Pediatrics P Frick, GA von Harnack, GA Martini, A Prader, HP Wolff		1980
Verhandlungen der Deutschen Gesellschaft für innere Medizin B Schlegel		1980
Sodium salicylate: Effect on determinants of bile flow and cholesterol solubility in rhesus monkeys MJ Cooper, AL Baker, AR Moossa	Digestive Diseases and Sciences	1980
Mechanism of Cholic Acid Protection in Lithocholate-Induced Intrahepatic Cholestasis in Rats G Kakis, IM Yousef	Gastroenterology	1980
Sodium Taurocholate Modifies the Bile Acid-Independent Fraction of Canalicular Bile Flow in the Rhesus Monkey AL Baker, RA Wood, AR Moossa, JL Boyer	Journal of Clinical Investigation	1979
Choleretic and cholestatic effects of infused bile salts in the rat R Drew, BG Priestly	Experientia	1979
Inhibition of hepatic Na+, K+-adenosinetriphosphatase in taurolithocholate-induced cholestasis in the rat J Reichen, G Paumgartner	Experientia	1979
Assessment of adverse effects of drugs on bile formation and bile composition G Paumgartner	Pharmacology & Therapeutics	1979
Studies on the Toxicity of Bile Acids in Infants Part 1. Effect of Orally Fed Bile Acids on the Hepatobiliary System in Rabbits H Nittono	Pediatrics International	1979
Bile acid profiles in urine of patients with liver diseases A Bremmelgaard, J Sjövall	European Journal of Clinical Investigation	1979
Urinary bile acids during development of recurrent cholestasis of pregnancy PA Thomassen	European Journal of Clinical Investigation	1979
Solution properties of sulfated monohydroxy bile salts MC Carey, SF Wu, JB Watkins	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1979
Studies in the rat on the hepatic subcellular distribution and biliary excretion of lithocholic acid RC Strange, IA Nimmo, IW Percy-Robb	Biochimica et Biophysica Acta (BBA) - General Subjects	1979
Alterations in the liver cell transmembrane potential following CCl4 and bile salt treatment of rats JR Olson, MJ Hosko, JM Fujimoto	Life Sciences	1979
Urinary bile acids in late pregnancy and in recurrent cholestasis of pregnancy PA Thomassen	European Journal of Clinical Investigation	1979
Failure of hypoactive hypertrophic smooth endoplasmic reticulum to produce cholestasis in rats R Drew, BG Priestly	Toxicology and Applied Pharmacology	1978
The influence of various bile salts and some cholephilic dyes on Na+, K+- and Mg2+-activated ATPase of rat liver in relation to cholestatic effects DK Meijer, RJ Vonk, JG Weitering	Toxicology and Applied Pharmacology	1978
Uneven distribution of enzymatic alterations on the liver cell surface in experimental extrahepatic cholestasis of rat G Toda, M Kako, H Oka, T Oda, Y Ikeda	Experimental and Molecular Pathology	1978
Hyperbilirubinemia and cholestasis PD Berk, NB Javitt	The American Journal of Medicine	1978
Bile and pancreatic secretion in chickens: the effects of bile salts, feeding and acid IW Caple, CG Halpin, T Heath	Comparative Biochemistry and Physiology Part A: Physiology	1978
Loss of microsomal components in drug-induced liver damage, in cholestasis and after administration of chemicals which stimulate heme catabolism FD Matteis	Pharmacology & Therapeutics. Part A: Chemotherapy, Toxicology and Metabolic Inhibitors	1978
Comparative effects of 2,4-dinitrophenol and sodium salicylate on bile secretion in the dog, cat, rabbit and guinea-pig PM Pugh, SC Rutishauser	General Pharmacology: The Vascular System	1978
Studies on Bile Acid Metabolism in Infancy and Childhood: Part 2. Bile Acid Metabolism in Neonatal hepatitis and Congenital Biliary Atresia T Matsudaira	Pediatrics International	1978
THE EFFECT OF INSULIN AND HYDROCORTISONE ON THE ISOLATED RAT LIVER AK Groufsky, RK Holland, D Lee	Australian and New Zealand Journal of Surgery	1978
Physiology of Membrane Disorders TE Andreoli, JF Hoffman, DD Fanestil		1978
Heme and Hemoproteins F Matteis, WN Aldridge		1978
Bile acid excretion: the alternate pathway in the hamster R Galeazzi, NB Javitt	Journal of Clinical Investigation	1977
Bile Salt Metabolism:II. Bile Salts and Disease CB Campbell, AE Cowen	Australian and New Zealand Journal of Medicine	1977
Evaluation of a new monkey model for the repeated study of bile secretory physiology RA Wood, AL Baker, AW Hall, JL Boyer, AR Moossa	Annals of Surgery	1977
Cholestatic steroid hormones inhibit taurocholate uptake into isolated rat hepatocytes LR Schwarz, M Schwenk, E Pfaff, H Greim	Biochemical Pharmacology	1977
Taurolithocholate inhibits taurocholate uptake by isolated hepatocytes at low concentrations M Schwenk, LR Schwarz, H Greim	Naunyn-Schmiedeberg's Archives of Pharmacology	1977
Cholestatic liver disease associated with diphenylhydantoin therapy: Possible pathogenic importance of altered bile salt metabolism CB Campbell, C McGuffie, AP Weedon, LW Powell	The American Journal of Digestive Diseases	1977
Increased Sulfation and Decreased 7α-Hydroxylation of Deoxycholic Acid in Ethinyl Estradiol-Induced Cholestasis in Rats RT Jensen, RA Davis, F Kern	Gastroenterology	1977
Internationale Arbeitstagung Gallenweg-Infektionen W Stille, R Timmler		1977
Taurolithocholate-Induced Cholestasis: Taurocholate, but not Dehydrocholate, Reverses Cholestasis and Bile Canalicular Membrane Injury TJ Layden, JL Boyer	Gastroenterology	1977
Disturbances of Bile Acid Metabolism in Cholestasis A Stiehl		1977
The effect of thyroid hormone on bile salt-independent bile flow and Na+, K+ -ATPase activity in liver plasma membranes enriched in bile canaliculi TJ Layden, JL Boyer	Journal of Clinical Investigation	1976
Measurement and alteration of the capacity of the distended biliary tree in the rat RE Peterson, JR Olson, JM Fujimoto	Toxicology and Applied Pharmacology	1976
Jaundice in pregnancy—1976 RT Holzbach	The American Journal of Medicine	1976
Hepatic Bile Formation NB Javitt	New England Journal of Medicine	1976
Bile Acid Glucuronides, II. Isolation and Identification of a Chenodeoxycholic Acid Glucuronide from Human Plasma in Intrahepatic Cholestasis P BACK	Hoppe-Seyler´s Zeitschrift für physiologische Chemie	1976
The Hepatobiliary System W Taylor		1976
Inhibition of Bile Formation by High Doses of Taurocholate in the Perfused Rat Liver R Herz, G Paumgartner, R Preisig	Scandinavian Journal of Gastroenterology	1976
The metabolism of 3alpha, 7alpha, 12alpha-trihydorxy-5beta-cholestan-26-oic acid in two siblings with cholestasis due to intrahepatic bile duct anomalies. An apparent inborn error of cholic acid synthesis RF Hanson, JN Isenberg, GC Williams, D Hachey, P Szczepanik, PD Klein, HL Sharp	Journal of Clinical Investigation	1975
Comparative effects of sodium taurodeoxycholate and sodium taurocholate on bile secretion in the rat, dog and rabbit SC Rutishauser, SL Stone	The Journal of Physiology	1975
Aspects of bile secretion in the rabbit SC Rutishauser, SL Stone	The Journal of Physiology	1975
The effect of sodium salicylate on bile secretion in the dog SC Rutishauser, SL Stone	The Journal of Physiology	1975
Hepatic disease in erythropoietic protoporphyria JR Bloomer, MJ Phillips, DL Davidson, G Klatskin	The American Journal of Medicine	1975
Pathobiology of Cell Membranes JR Robinson	Pathobiology of Cell Membranes	1975
Scanning Electron Microscopy of the Rat Liver TJ Layden, J Schwarz, JL Boyer	Gastroenterology	1975
Bile salts and liver disease in childhood NB Javitt	Postgraduate medical journal	1974
URINARY BILE ACID CONJUGATES IN EXTRAHEPATIC BILIARY ATRESIA A Norman, B Strandvik, Ö Ojamäe	Acta paediatrica (Oslo, Norway : 1992)	1974
Bile Acid Metabolism and Fat Absorption in Newborn Infants JB Watkins	Pediatric Clinics of North America	1974
Achtzigster Kongress JF Bergmann		1974
Bile acid metabolism in infants and children GM Murphy, E Signer	Gut	1974
Mechanisms and Control of Secretion of Bile Water and Electrolytes S Erlinger, D Dhumeaux	Gastroenterology	1974
Identification and quantitative determination of urinary bile acids excreted in cholestasis P Back	Clinica Chimica Acta	1973
An analysis of the choleretic effect of insulin EG Lundy, J Migliori, RS Jones	Journal of Surgical Research	1973
Cholesterol Gallstones IW Percy-Robb	Scottish Medical Journal	1973
The Bile Acids, Chemistry, Physiology, and Metabolism PP Nair, D Kritchevsky		1973
Inhibition of Bile Salt-Independent Bile Formation by Indocyanine Green W Horak, G Grabner, G Paumgartner	Gastroenterology	1973
Biliary Excretion of Bile Acids, Lecithin, and Cholesterol in Hamsters with Gallstones HO Wheeler	Gastroenterology	1973
Effect of Phenobarbital on the Ethynyl Estradiol-Induced Cholestasis in the Rat JJ Gumucio, L Accatino, AM Macho, A Contreras	Gastroenterology	1973
Bile Acid Synthesis in Man: Metabolism of 7α-Hydroxycholesterol-¹⁴C and 26-Hydroxycholesterol-³H KE Anderson, E Kok, NB Javitt	Journal of Clinical Investigation	1972
Coproporphyrin I and III excretion in bile and urine N Kaplowitz, N Javitt, A Kappas	Journal of Clinical Investigation	1972
Alterations in Liver Plasma Membranes and their Possible Role in Cholestasis FR Simon, IM Arias	Gastroenterology	1972
The Enterohepatic Circulation RH Dowling	Gastroenterology	1972
Cholestasis induced by sodium taurolithocholate in isolated hamster liver JE King, LJ Schoenfield	Journal of Clinical Investigation	1971
Composition of basal and stimulated hepatic bile in baboons, and the formation of cholesterol gallstones CK McSherry, F Glenn, NB Javitt	Proceedings of the National Academy of Sciences	1971
Cholesterol gallstones and the chemical composition of bile in baboons CK McSherry, NB Javitt, JM de Carvalho, F Glenn	Annals of Surgery	1971
Gas-liquid-chromatographic determination of bile acids in bile CD Klaassen	Clinica Chimica Acta	1971
The cholestatic syndrome—1971 NB Javitt	The American Journal of Medicine	1971
The Bile Acids Chemistry, Physiology, and Metabolism PP Nair, D Kritchevsky		1971
Studies on the Mechanism of the Ethynylestradiol Impairment of Bile Flow and Bile Salt Excretion in the Rat JJ Gumucio, VD Valdivieso	Gastroenterology	1971
Bile Salt Synthesis in Transplanted Human Liver NB Javitt, MH Shiu, JG Fortner	Gastroenterology	1971
The effect of sodium taurocholate on the hepatic metabolism of sulfobromophthalein sodium (BSP). The role of bile flow JL Boyer, RL Scheig, G Klatskin	Journal of Clinical Investigation	1970
Hydrocortisone choleresis in the dog V Macarol, TQ Morris, KJ Baker, SE Bradley	Journal of Clinical Investigation	1970
Pathophysiology of cholestasis H Popper, F Schaffner	Human Pathology	1970
Some aspects of the interaction between natural and synthetic female sex hormones and the liver H Adlercreutz, R Tenhunen	The American Journal of Medicine	1970
Mechanism of cholestasis. 2. Effect of bile acids on the microsomal electron transfer system F Hutterer, PG Bacchin, H Denk, JB Schenkman, F Schaffner, H Popper	Life Sciences	1970
Solubility of Bile Salts DM Small, W Admirand	Nature	1969
CHOLESTASIS IS THE RESULT OF HYPOACTIVE HYPERTROPHIC SMOOTH ENDOPLASMIC RETICULUM IN THE HEPATOCYTE F Schaffner, H Popper	The Lancet	1969
Essays in Toxicology RP Smith	Essays in Toxicology	1969
Cholestyramine Treatment of Diarrhea Associated with Ileal Resection AF Hofmann, JR Poley	New England Journal of Medicine	1969
Metabolic Effects of Gonadal Hormones and Contraceptive Steroids HA Salhanick, DM Kipnis, RL Wiele		1969
Bile Salt Regulation of Hepatic Excretory Function NB Javitt	Gastroenterology	1969
Metabolism of Cholest-5-ene-3β, 26-diol in the Rat and Hamster N Wachtel, S Emerman, NB Javitt	The Journal of biological chemistry	1968
Jaundice S Sherlock	British medical journal	1962

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