A new method has been described for measuring the pressure and resistance to blood flow in the pulmonary arteries, capillaries, and veins. Studies were performed in dog isolated lung lobes perfused at constant flow with blood from a donor dog. Pulmonary artery and vein volume and total lobar blood volume were measured by the ether plethysmograph and dyedilution techniques. The longitudinal distribution of vascular resistance was determined by analyzing the decrease in perfusion pressure caused by a bolus of low viscosity liquid introduced into the vascular inflow of the lobe.
Jerome S. Brody, Edward J. Stemmler, Arthur B. DuBois
Title and authors | Publication | Year |
---|---|---|
Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca2+ signaling
Balistrieri A, Makino A, Yuan JX |
Physiological reviews | 2022 |
Effects of recombinant human soluble thrombomodulin on neutrophil extracellular traps in the kidney of a mouse model of endotoxin shock.
Harada T, Shimomura Y, Nishida O, Maeda M, Kato Y, Nakamura T, Kuriyama N, Komura H |
Fujita medical journal | 2022 |
Hemodynamic function of the right ventricular-pulmonary vascular-left atrial unit: normal responses to exercise in healthy adults
SP Wright, TG Dawkins, ND Eves, R Shave, RJ Tedford, S Mak |
American journal of physiology. Heart and circulatory physiology | 2021 |
Multiscale Modeling of Superior Cavopulmonary Circulation: Hemi-Fontan and Bidirectional Glenn Are Equivalent
E Kung, C Corsini, A Marsden, I Vignon-Clementel, G Pennati, R Figliola, TY Hsia, A Taylor, S Khambadkone, S Schievano, M de Leval, E Bove, A Dorfman, GH Baker, A Hlavacek, F Migliavacca, G Pennati, G Dubini, A Marsden, I Vignon-Clementel, R Figliola, J McGregor, TY Hsia |
Seminars in Thoracic and Cardiovascular Surgery | 2019 |
Lung disease and pulmonary hypertension in the premature infant
LA Christ, JM Sucre, DB Frank |
Progress in Pediatric Cardiology | 2019 |
Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation
Y Gao |
Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation | 2017 |
Re-endothelialization of rat lung scaffolds through passive, gravity-driven seeding of segment-specific pulmonary endothelial cells: Re-endothelialization of rat lung scaffolds
ME Scarritt, NC Pashos, JM Motherwell, ZR Eagle, BJ Burkett, AN Gregory, R Mostany, DJ Weiss, DF Alvarez, BA Bunnell |
Journal of Tissue Engineering and Regenerative Medicine | 2017 |
Re-endothelialization of rat lung scaffolds through passive, gravity-driven seeding of segment-specific pulmonary endothelial cells: Re-endothelialization of rat lung scaffolds
ME Scarritt, NC Pashos, JM Motherwell, ZR Eagle, BJ Burkett, AN Gregory, R Mostany, DJ Weiss, DF Alvarez, BA Bunnell |
Journal of Tissue Engineering and Regenerative Medicine | 2017 |
Synchrotron Imaging Shows Effect of Ventilator Settings on Intrabreath Cyclic Changes in Pulmonary Blood Volume
L Porra, L Broche, L Dégrugilliers, G Albu, I Malaspinas, C Doras, M Wallin, M Hallbäck, W Habre, S Bayat |
American journal of respiratory cell and molecular biology | 2017 |
Computational modelling of the respiratory system: Discussion of coupled modelling approaches and two recent extensions
CJ Roth, L Yoshihara, M Ismail, WA Wall |
Computer Methods in Applied Mechanics and Engineering | 2016 |
Pulmonary embolism is more prevalent than deep vein thrombosis in cases of chronic obstructive pulmonary disease and interstitial lung diseases
SH Park |
SpringerPlus | 2016 |
The Vital Role of the Right Ventricle in the Pathogenesis of Acute Pulmonary Edema
DH MacIver, AL Clark |
The American Journal of Cardiology | 2015 |
Comparative Biology of the Normal Lung
JL Peake, KE Pinkerton |
Comparative Biology of the Normal Lung | 2015 |
Biofluid Mechanics
DA Rubenstein, W Yin, MD Frame |
Biofluid Mechanics | 2015 |
PanVascular Medicine
AN Rizzo, DR Fraidenburg, JX Yuan |
PanVascular Medicine | 2015 |
Radius exponent in elastic and rigid arterial models optimized by the least energy principle
Y Nakamura, S Awa |
Physiological Reports | 2014 |
Comprehensive Physiology
SN Cheuvront, RW Kenefick |
Comprehensive Physiology | 2014 |
Alteration of Factors Associated with Coagulation in Provoked Pulmonary Embolism
JW Lee, HI Jung, HJ Kim, WI Choi |
Clinical & Experimental Thrombosis and Hemostasis | 2014 |
Patient-specific assessment of cardiovascular function by combination of clinical data and computational model with applications to patients undergoing Fontan operation: ASSESSMENT OF CARDIOVASCULAR FUNCTION USING A COMPUTATIONAL METHOD
F Liang, K Sughimoto, K Matsuo, H Liu, S Takagi |
International Journal for Numerical Methods in Biomedical Engineering | 2014 |
Hemodynamic performance of the Fontan circulation compared with a normal biventricular circulation: a computational model study
F Liang, H Senzaki, C Kurishima, K Sughimoto, R Inuzuka, H Liu |
American journal of physiology. Heart and circulatory physiology | 2014 |
Hypoxic Pulmonary Vasoconstriction
ER Swenson |
High Altitude Medicine & Biology | 2013 |
Partitioning pulmonary vascular resistance using the reservoir-wave model
JC Bouwmeester, I Belenkie, NG Shrive, JV Tyberg |
Journal of applied physiology | 2013 |
Mechanics and Function of the Pulmonary Vasculature: Implications for Pulmonary Vascular Disease and Right Ventricular Function
S Lammers, D Scott, K Hunter, W Tan, R Shandas, KR Stenmark |
Comprehensive Physiology | 2012 |
Mechanics and Function of the Pulmonary Vasculature: Implications for Pulmonary Vascular Disease and Right Ventricular Function
S Lammers, D Scott, K Hunter, W Tan, R Shandas, KR Stenmark |
Comprehensive Physiology | 2012 |
Mechanics and Function of the Pulmonary Vasculature: Implications for Pulmonary Vascular Disease and Right Ventricular Function
S Lammers, D Scott, K Hunter, W Tan, R Shandas, KR Stenmark |
Comprehensive Physiology | 2012 |
Hypoxic pulmonary vasoconstriction.
Sylvester JT, Shimoda LA, Aaronson PI, Ward JP |
Physiological reviews | 2012 |
Flow in the Lungs
DA Rubenstein, W Yin, MD Frame |
Biofluid Mechanics | 2012 |
Peripheral Circulation
MH Laughlin, MJ Davis, NH Secher, JJ van Lieshout, AA Arce-Esquivel, GH Simmons, SB Bender, J Padilla, RJ Bache, D Merkus |
Comprehensive Physiology | 2012 |
18FDG PET imaging can quantify increased cellular metabolism in pulmonary arterial hypertension: A proof-of-principle study
G Hagan, M Southwood, C Treacy, RM Ross, E Soon, J Coulson, K Sheares, N Screaton, J Pepke-Zaba, NW Morrell, JH Rudd |
Pulmonary circulation | 2011 |
Model combining hydrodynamics and fractal theory for analysis of in vivo peripheral pulmonary and systemic resistance of shunt cardiac defects
Y Nakamura, S Awa, H Kato, YM Ito, A Kamiya, T Igarashi |
Journal of Theoretical Biology | 2011 |
18 FDG PET Imaging can Quantify Increased Cellular Metabolism in Pulmonary Arterial Hypertension: A Proof-of-Principle Study
G Hagan, M Southwood, C Treacy, RM Ross, E Soon, J Coulson, K Sheares, N Screaton, J Pepke-Zaba, NW Morrell, JH Rudd |
Pulmonary circulation | 2011 |
Murray and Nadel's Textbook of Respiratory Medicine
MA Matthay, TR Martin |
Murray and Nadel's Textbook of Respiratory Medicine | 2010 |
Model of pulmonary fluid traffic homeostasis based on respiratory cycle pressure, bidirectional bronchiolo-pulmonar shunting and water evaporation
S Kurbel, B Kurbel, D Gulam, B Spajić |
Medical Hypotheses | 2010 |
Textbook of Pulmonary Vascular Disease
, JG Garcia, JB West, CA Hales, S Rich, SL Archer |
2010 | |
Biomechanics
R Hochmuth, R Waugh |
Biomechanics | 2007 |
Functions and Control of the Pulmonary Circulation
E Mazza, DB Taichman |
Pulmonary Vascular Disease | 2006 |
Increased Pulmonary Venous Resistance Contributes to Increased Pulmonary Artery Diastolic???Pulmonary Wedge Pressure Gradient in Acute Respiratory Distress Syndrome:
C Her, S Mandy, M Bairamian |
Anesthesiology | 2005 |
Cellular and molecular mechanisms of pulmonary vascular remodeling: role in the development of pulmonary hypertension
M Mandegar, YC Fung, W Huang, CV Remillard, LJ Rubin, JX Yuan |
Microvascular Research | 2004 |
Whole Organ Approaches to Cellular Metabolism
JB Bassingthwaighte, JH Linehan, CA Goresky |
1998 | |
Evidence for specific regional patterns of responses to different vasoconstrictors and vasodilators in sheep isolated pulmonary arteries and veins
BK Kemp, JJ Smolich, TM Cocks |
British Journal of Pharmacology | 1997 |
PULMONARY CAPILLARY PRESSURE
MM Levy |
Critical Care Clinics | 1996 |
Permeability of the endothelium and partitioning of the pulmonary blood flow resistance in isolated perfused pig lungs: Effects of breed and age
P Gustin, B Urbain, A Delaunois, K Zeimes, M Ansay |
Veterinary Research Communications | 1992 |
Elevated Pulmonary Artery Systolic Storage Volume Associated with Improved Ventilation-to-Perfusion Ratios in Acute Respiratory Failure
C Her, A Kosse, DE Lees |
Chest | 1992 |
Pulmonary vascular pressure profile in adult ferrets: measurements in vivo and in isolated lungs
JU Raj, P KAAPA, R HILLYARD, J ANDERSON |
Acta Physiologica Scandinavica | 1991 |
Baroreceptor Reflexes
PB Persson, HR Kirchheim |
1991 | |
Pulmonary vascular pressure profile in 2–3-week-old, 5–6-week-old and adult ferrets
JU Raj, R Hillyard, P Kaapa, J Anderson, M Gropper |
Respiration Physiology | 1990 |
Microvascular Mechanics
JS Lee, TC Skalak |
1989 | |
A continuum model of the blood flow in the lung microcirculation
W Wangyi, H Xiaoyi |
Acta Mechanica Sinica | 1988 |
Time shift in ventilation-induced density fluctuation of arterial blood
MV Evans, J Lee, L Lee |
Annals of Biomedical Engineering | 1987 |
The Pulmonary Circulation in Health and Disease
J Hughes |
The Pulmonary Circulation in Health and Disease | 1987 |
Ventricular/Vascular Coupling
FC Yin |
1987 | |
Determinants of pulmonary blood volume. Effects of acute changes in pulmonary vascular pressures and flow
J Thorvaldson, A Ilebekk, S Leraand, F Kiil |
Acta Physiologica Scandinavica | 1984 |
Nitroglycerin therapy in the management of pulmonary hypertensive disorders
M Packer, JL Halperin, KM Brooks, EB Rothlauf, WH Lee |
The American Journal of Medicine | 1984 |
Biodynamics: Circulation
YC Fung |
1984 | |
Pulmonary blood flow
A Sniderman, T Burdon, J Homan, TA Salerno |
The Journal of Thoracic and Cardiovascular Surgery | 1984 |
Influence of perfusate PO2 on hypoxic pulmonary vasoconstriction in rats
C Marshall, BE Marshall |
Circulation research | 1983 |
PULMONARY MICROCIRCULATORY HEMODYNAMICS
CA Dawson, JH Linehan, DA Rickaby |
Annals of the New York Academy of Sciences | 1982 |
Microvascular pressure distribution and responses of pulmonary allografts and cheek pouch arterioles in the hamster to oxygen
MJ Davis, WL Joyner, JP Gilmore |
Circulation research | 1981 |
The pathogenesis of pulmonary edema
NC Staub |
Progress in Cardiovascular Diseases | 1980 |
Structure and Function of the Circulation
CJ Schwartz, NT Werthessen, S Wolf |
1980 | |
Direct Measurement of Microvascular Pressures in the Isolated Perfused Dog Lung
J Bhattacharya, NC Staub |
Science | 1980 |
Bronchitis · Asthma Emphysem
WT Ulmer, H Bachofen, H Fabel, R Ferlinz, E Fuchs, W Hartung, P Hilpert, E Kammler, B Rasche, HS Stender |
1979 | |
Microscopic anatomy of the pulmonary vascular bed in the cat lung
JA Rhodin |
Microvascular Research | 1978 |
The chest radiograph: A systematic approach to interpretation for the internist
AF Turner |
Current Problems in Cardiology | 1978 |
Distribution of extravascular fluid volumes in isolated perfused lungs measured with H215O
T Jones, HA Jones, CG Rhodes, PD Buckingham, JM Hughes |
Journal of Clinical Investigation | 1976 |
The physiology of the pulmonary circulation and methods of study
GR Barer |
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology | 1976 |
Hypoxia on the pulmonary circulation. How and where it acts
AP Fishman |
Circulation research | 1976 |
Pulmonary vascular response to atrial septal defect closure in children
CL Lucas, BR Wilcox, NA Coulter |
Journal of Surgical Research | 1975 |
Effect of increased vascular pressure on lung fluid balance in unanesthetized sheep
AJ rd, TR Vaughan, KL Brigham, WC Woolverton, NC Staub |
Circulation research | 1975 |
Quantitative structural analysis of pulmonary vessels in isolated ventricular septal defect in infancy
A Hislop, SG Haworth, EA Shinebourne, L Reid |
Heart (British Cardiac Society) | 1975 |
Mechanisms underlying vasomotor regulation of regional pulmonary blood flow in normal and disease states
EH Bergofsky |
The American Journal of Medicine | 1974 |
Engineering Principles in Physiology
JJ Distefano |
Engineering Principles in Physiology | 1973 |
Pulmonary Blood Volume and Haemodynamic Changes During Steady Lung Inflations in Dogs
H Pouleur, PM Jaumin, AA Charlier |
Acta Anaesthesiologica Scandinavica | 1973 |
Pulsatile uptake of CO in the human lung
HA Menkes, K Sera, RM Rogers, RW Hyde, RE 2nd, AB DuBois |
Journal of Clinical Investigation | 1970 |
The cite of action of nerves in the pulmonary vascular bed in the dog
IB Daly, DJ Ramsay, BA Waaler |
The Journal of Physiology | 1970 |
Dynamic intravascular pressures in the microvessels of the frog lung
JE Maloney, BL Castle |
Respiration Physiology | 1970 |
Differential reactivity in the pulmonary circulation
JS Brody, EJ Stemmler |
Journal of Clinical Investigation | 1968 |