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Citations to this article

Plasma Lipoproteins in Liver Disease: I. Immunologically Distinct Low-Density Lipoproteins in Patients with Biliary Obstruction
Sam Switzer
Sam Switzer
Published November 1, 1967
Citation Information: J Clin Invest. 1967;46(11):1855-1866. https://doi.org/10.1172/JCI105676.
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Research Article Article has an altmetric score of 3

Plasma Lipoproteins in Liver Disease: I. Immunologically Distinct Low-Density Lipoproteins in Patients with Biliary Obstruction

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Abstract

Sera from patients with extrahepatic biliary obstruction were found to have an abnormal lipoprotein (obstructive lipoprotein) which failed to react with antibodies to normal lipoproteins of d < 1.063. Preparations of this abnormal lipoprotein made by a combination of immunoprecipitation and multiple polyanion precipitations revealed a high content of free cholesterol (26%) and phospholipids (61%) but only trace amounts of cholesterol esters and triglycerides. Protein content varied from 13% to a corrected low of 5% when ultracentrifugation was also performed. Amino acid analyses of the latter preparations resembled that of lipoproteins of d < 1.006.

Authors

Sam Switzer

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Total citations by year

Year: 2019 2018 2013 2012 2011 2004 1996 1995 1993 1990 1988 1987 1986 1985 1984 1983 1982 1980 1979 1978 1977 1976 1975 1974 1973 1972 1971 1970 1969 1968 1965 Total
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Citations to this article (106)

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European Journal of Clinical Investigation 1977
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Immunochemical Studies of Lipoproteins in Cholestasis
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Bile Flow and Biliary Lipid Secretion Following Release of Biliary Obstruction in Man
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Scandinavian Journal of Gastroenterology 1975
Quantitative Determination of the Abnormal Lipoprotein of Cholestasis, LP-X, in Liver Disease
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Scandinavian Journal of Gastroenterology 1975
The Abnormal ‘Lipoprotein of Cholestasis’, Lipoprotein-X
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