Inhalation of aerosols of citric acid, histamine phosphate, or carbon dust, or air cooled to - 20°C or rapid respiratory maneuvers (inspiration or expiration) results in an increase in airway resistance in some patients with asthma or bronchitis. It has been shown previously in animals that stimulation of cough receptors results in bronchoconstriction through efferent cholinergic pathways. In the patients studied, the administration of atropine sulfate, which would block such pathways, abolished the bronchoconstrictor effects of all the stimuli except large doses of histamine, which may exert a direct effect on airway smooth muscle. These data suggest that sensitized cough receptors may be involved in triggering reflex airway constriction in such patients.
B. G. Simonsson, F. M. Jacobs, J. A. Nadel
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Clinical & Experimental Allergy | 1981 |
The effect of ipratropium and fenoterol on methacholine- and histamine-induced bronchoconstriction
J Bandouvakis, A Cartier, R Roberts, G Ryan, FE Hargreave |
British Journal of Diseases of the Chest | 1981 |
The direct effect of temperature on airway smooth muscle
M Souhrada, JF Souhrada |
Respiration Physiology | 1981 |
Physical Activity and the Asthmatic
AR Morton, KD Fitch, AG Hahn |
The Physician and Sportsmedicine | 1981 |
The Effects of Oral Doses of Theophylline and Fenoterol on Exercise-Induced Asthma
PA Eggleston, PP Beasley, RT Kindley |
Chest | 1981 |
Effects of Inhaled Atropine in Chronic Bronchitis
TJ Witek, NL Dean, EN Schachter |
Chest | 1981 |
Airway Responsiveness and Chronic Airway Obstruction
CH Fanta, RH Ingram |
Medical Clinics of North America | 1981 |
Methods in Clinical Pharmacology—Respiratory System
JB Howell, AE Tattersfield |
1981 | |
Histamine-Induced Bronchospasm
B Hegardt, O Löwhagen, N Svedmyr |
Allergy | 1980 |
Comparison of bronchial reactivity to histamine and methacholine in asthmatics
CM Salome, RE Schoeffel, AJ Woolcock |
Clinical & Experimental Allergy | 1980 |
A non-pharmacologic approach to the treatment of exercise-induced bronchospasm
EN Schachter, M Lee, H Gerhard, S Brown |
The Yale journal of biology and medicine | 1980 |
A MODEL OF IRRITANT-INDUCED BRONCHOCONSTRICTION IN THE SPONTANEOUSLY BREATHING GUINEA-PIG
C Allott, D Evans, P Marshall |
British Journal of Pharmacology | 1980 |
The Effect of Atropine Inhalation in “Irreversible” Chronic Bronchitis
JJ Marini, S Lakshminarayan |
Chest | 1980 |
Verhandlungen der Deutschen Gesellschaft für innere Medizin
B Schlegel |
1980 | |
Cholinergic blockade in the prevention of exercise-induced asthma
JP Hartley, BH Davies |
Thorax | 1980 |
Methods of study of airway smooth muscle and its physiology
HL Hahn, JA Nadel |
Pharmacology & Therapeutics | 1979 |
Severe Asthmatic Reaction During Long-Term Treatment with Disodium Cromoglycate Powder Inhalations
J Serup |
Acta Medica Scandinavica | 1979 |
A controlled study on the preventive effect of ketotifen, an antiallergic agent, on methacholine-induced bronchoconstriction in asthmatics
K Mattson, H Poppius, R Hurme |
Clinical & Experimental Allergy | 1979 |
Lung volumes
S Freedman |
British Journal of Clinical Pharmacology | 1979 |
Assessing change in airway calibre--measurement of airway resistance
AE Tattersfield, IM Keeping |
British Journal of Clinical Pharmacology | 1979 |
Bronchoconstriction in potroom workers
M Sarić, E Zuskin, M Gomzi |
British journal of industrial medicine | 1979 |
Assessment of changes in airway calibre I. Tests of forced expiration
NB Pride |
British Journal of Clinical Pharmacology | 1979 |
Bronchial provocation tests
MK Benson |
British Journal of Clinical Pharmacology | 1979 |
Assessing change in airway calibre-measurement of airway resistance
AE Tattersfield, IM Keeping |
British Journal of Clinical Pharmacology | 1979 |
Chronic Cough as the Sole Presenting Manifestation of Bronchial Asthma
WM Corrao, SS Braman, RS Irwin |
New England Journal of Medicine | 1979 |
Temperature dependence of tracheal smooth muscle response to isoproterenol
D Downing, RC Kolbeck, JE Holl, ED Bransome, WA Speir |
Life Sciences | 1979 |
Exercise-Induced Asthma: Observations on the Initiating Stimulus
HL Bleich, MJ Moore, ER McFadden, RH Ingram |
New England Journal of Medicine | 1979 |
Effects of Breathing Warm Humidified Air on Bronchoconstriction Induced by Body Cooling and by Inhalation of Methacholine
DJ Horton, WY Chen |
Chest | 1979 |
Effect of Ammonia on Nasal Resistance in Atopic and Nonatopic Subjects
JA McLean, KP Mathews, WR Solomon, PR Brayton, NK Bayne |
The Annals of otology, rhinology, and laryngology | 1979 |
Cellular, Molecular, and Clinical Aspects of Allergic Disorders
S Gupta, RA Good |
1979 | |
Comparison of pirbuterol and pirbuterol and hydroxyzine in patients with reversible airway obstruction
H Poppius, H Lehti, B Stenius-Aarniala |
European Journal of Clinical Pharmacology | 1979 |
The role of adrenoceptors in bronchial asthma
K R Patel |
Journal of the Royal College of Physicians of London | 1979 |
Mechanisms of the bronchoconstrictor effects of deep inspiration in asthmatic patients
P Gayrard, J Orehek, C Grimaud, J Charpin |
Thorax | 1979 |
Bronchitis · Asthma Emphysem
WT Ulmer, H Bachofen, H Fabel, R Ferlinz, E Fuchs, W Hartung, P Hilpert, E Kammler, B Rasche, HS Stender |
1979 | |
PROPRANOLOL ABUSE OR PERFORMER'S MATURATION?
C Swartz |
The Lancet | 1978 |
SHOULD ASTHMATIC PATIENTS LAUGH?
P Gayrard |
The Lancet | 1978 |
Drugs in the treatment of asthma
N Svedmyr, BG Simonsson |
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology | 1978 |
Changes of airway smooth muscle in experimental asthma
JF Souhrada |
Respiration Physiology | 1978 |
Influence of Tracheal Muscular Tone on the Initiation of Cough Reflex
S Yanaura, T Hosokawa, H Kitagawa, Y Yamatake |
The Japanese Journal of Pharmacology | 1978 |
The Frequency and Importance of Bronchial Hyperreactivity in Patients With Allergic and Non-Allergic Rhinitis
A Dziedziczko, R Gniazdowski |
Acta Oto-laryngologica | 1977 |
Effect of deep inspiration on airway conductance in subjects with allergic rhinitis and allergic asthma
JE Fish, VI Peterman, DW Cugell |
Journal of Allergy and Clinical Immunology | 1977 |
Asthma induced by sulphur dioxide, benzoate and tartrazine contained in orange drinks
BJ Freedman |
Clinical & Experimental Allergy | 1977 |
Protective effect of drugs on histamine-induced asthma
DW Cockcroft, DN Killian, JJ Mellon, FE Hargreave |
Thorax | 1977 |
Bronchoconstrictor drugs
BG Simonsson, N Svedmyr |
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology | 1977 |
Enhancement of Exercise-Induced Asthma by Cold Air
RH Strauss, ER McFadden, RH Ingram, JJ Jaeger, DR Stearns |
New England Journal of Medicine | 1977 |
Some experimental models of acute asthma
J G Widdicombe |
Journal of the Royal College of Physicians of London | 1977 |
Bronchial secretion from normal human airways after inhalation of prostaglandin F2alpha, acetylcholine, histamine, and citric acid
MT Lopez-Vidriero, I Das, AP Smith, R Picot, L Reid |
Thorax | 1977 |
Time course of bronchoconstrictive response in asthmatic subjects to reduced temperature
JM Ramsey |
Thorax | 1977 |
INVOLVEMENT OF HISTAMINE H1- AND H2-RECEPTORS IN INDUCED ASTHMAS IN DOGS
Y YAMATAKE, S SASAGAWA, S YANAURA, N KOBAYASHI |
The Japanese Journal of Pharmacology | 1977 |
Effect of short-term, low-level nitrogen dioxide exposure on bronchial sensitivity of asthmatic patients
J Orehek, JP Massari, P Gayrard, C Grimaud, J Charpin |
Journal of Clinical Investigation | 1976 |
Hypersensitivity to acetylsalicylic acid (ASA) and tartrazine in patients with asthma
BS Stenius, M Lemola |
Clinical & Experimental Allergy | 1976 |
Factors in allergen-induced asthma: relevance of the intensity of the airways allergic reaction and non-specific bronchial reactivity
D Killian, DW Cockcroft, FE Hargreave, J Dolovich |
Clinical & Experimental Allergy | 1976 |
Interaction between bronchoconstrictor stimuli on human airway smooth muscle
C Mitchell, A Bouhuys |
The Yale journal of biology and medicine | 1976 |
Climate and Environment Change in Patients With Chronic Airway Obstruction: A Pilot Study on the Effects on Lung Function
BE Skoogh, BG Simonsson, AG Berggren, Z Bergstrouml;m, M Johansson |
Archives of Environmental Health An International Journal | 1976 |
Fiberoptic Bronchoscopy in Bronchial Asthma
SA Sahn, C Scoggin |
Chest | 1976 |
Leistungsbegrenzung von seiten der Lunge
WT Ulmer |
1976 | |
Therapeutic value of anticholinergic agents in chronic obstructive pulmonary diseases
E Vastag, L Nagy, G Miskovits |
European Journal of Clinical Pharmacology | 1976 |
The relation of urban atmospheric variables to asthmatic bronchoconstriction
JM Ramsey |
Bulletin of Environmental Contamination and Toxicology | 1976 |
Effect of sodium cromoglycate on asthmatic reactions to environmental temperature changes
AB Breslin, J Pepys |
Clinical & Experimental Allergy | 1975 |
Effect of maximal respiratory manoeuvres on bronchial sensitivity of asthmatic patients as compared to normal people
J Orehek, P Gayrard, C Grimaud, J Charpin |
British medical journal | 1975 |
The effect of prostaglandin F2β on expiratory flow rates
P Hamosh, AM da Silva |
Prostaglandins | 1975 |
Bronchial hyperreactivity
MK Benson |
British Journal of Diseases of the Chest | 1975 |
Exertional Dyspnea and Cough as Preludes to Acute Attacks of Bronchial Asthma
ER Fadden |
New England Journal of Medicine | 1975 |
Effect of atropine on sputum production
MT Lopez-Vidriero, J Costello, TJ Clark, I Das, EE Keal, L Reid |
Thorax | 1975 |
Beta-adrenergic function in airways of healthy and asthmatic subjects
P Gayrard, J Orehek, C Grimaud, J Charpin |
Thorax | 1975 |
The Role of Bronchoconstriction in Cough Reflex
S Yanaura, T Nishimura, M Sakamoto, T Sasao |
The Japanese Journal of Pharmacology | 1975 |
Unusual side effects during disodium cromoglycate (intal) therapy in a case of bronchial asthma (case report)
J Müller, J Kowalski |
Lung | 1975 |
BRONCHIAL REACTIVITY TO INHALED HISTAMINE IN ASTHMATIC PATIENTS, BEFORE AND AFTER ADMINISTRATION OF ATROPINE, PHENTOLAMINE OR DISODIUM CROMOGLYCATE
KO Pegelow |
Allergy | 1974 |
PARASYMPATHETIC NERVOUS CONTROL OF AIRWAY SMOOTH MUSCLE
JA Nadel |
Annals of the New York Academy of Sciences | 1974 |
Recent advances in the pathophysiology of asthma
AF Wilson, SP Galant |
The Western journal of medicine | 1974 |
Asthma: Current Concepts
H Levison, C Collins-Williams, AC Bryan, BJ Reilly, RP Orange |
Pediatric Clinics of North America | 1974 |
Immunological Aspects of Allergy and Allergic Diseases
E Rajka, S Korossy |
1974 | |
Normal Airways Conductance at Different Lung Volumes
BE Skoogh |
Scandinavian Journal of Clinical & Laboratory Investigation | 1973 |
Bronchial hyperreactivity to prostaglandin F 2 and histamine in patients with asthma
AA Mathé, P Hedqvist, A Holmgren, N Svanborg |
British medical journal | 1973 |
Sensory Irritation by Airborne Chemicals
Y Alarie |
Critical Reviews in Toxicology | 1973 |
Bronchopulmonary Diseases: Immunologic Perspectives
DA Mathison, DD Stevenson |
Postgraduate Medicine | 1973 |
VALEUR DU TEST DE PROVOCATION PAR ALLERGENES INHALES DANS L'ASTHME
P Gayrard, J Orehek, C Boutin, J Charpin |
Allergy | 1972 |
Where is the allergic reaction in ragweed asthma? *1II. Demonstration of ragweed antigen in airborne particles smaller than pollen
WW Busse, CE Reed, JH Hoehne |
Journal of Allergy and Clinical Immunology | 1972 |
Exercise-induced airways constriction
BG Simonsson, BE Skoogh, B Ekström-Jodal |
Thorax | 1972 |
Medical Hazards of Aerosols: First of Two Parts
IL Bernstein |
Postgraduate Medicine | 1972 |
Cough syncope
AM Jain |
The Indian Journal of Pediatrics | 1971 |
Mechanism of bronchoconstriction due to beta adrenergic blockade
MH Grieco, RN Pierson |
Journal of Allergy and Clinical Immunology | 1971 |
Respiratory mechanics and dust exposure in byssinosis
A Bouhuys, KP van de Woestijne |
Journal of Clinical Investigation | 1970 |
Acute massive pulmonary collapse
NJ Coroneos, J Lawrence, TA Torda |
Anaesthesia | 1970 |
Cough syncope in children with asthma
RM Katz |
The Journal of Pediatrics | 1970 |
Cardiopulmonary effects of methacholine in asthmatic and normal subjects
MH Grieco, RN Pierson |
Journal of Allergy | 1970 |
The Effect of Cold Air Inhalation on Respiratory Gas Exchange During Exercise in Patients With Chronic Obstructive Pulmonary Disease
YC Hsieh, R Frayser, JC Ross |
Chest | 1970 |
Psychosomatic Aspects of Respiratory Disorders
M Stein, TJ Luparello |
Postgraduate Medicine | 1970 |
Maximum expiratory flow rates in induced bronchoconstriction in man
A Bouhuys, VR Hunt, BM Kim, A Zapletal |
Journal of Clinical Investigation | 1969 |
Asthmatic Hyperresponsiveness
EM Heimlich |
Pediatric Clinics of North America | 1969 |
Psychosomatic Study and Treatment of Asthmatic Children
CJ Falliers |
Pediatric Clinics of North America | 1969 |
THE CHANGING PATTERN OF MORTALITY FROM ASTHMA IN AUSTRALIA: 2. MORTALITY AND MODERN THERAPY
B Gandevia |
The Medical Journal of Australia | 1968 |