Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Role of Autonomic Nervous System and the Cough Reflex in the Increased Responsiveness of Airways in Patients with Obstructive Airway Disease
B. G. Simonsson, … , F. M. Jacobs, J. A. Nadel
B. G. Simonsson, … , F. M. Jacobs, J. A. Nadel
Published November 1, 1967
Citation Information: J Clin Invest. 1967;46(11):1812-1818. https://doi.org/10.1172/JCI105671.
View: Text | PDF
Research Article Article has an altmetric score of 6

Role of Autonomic Nervous System and the Cough Reflex in the Increased Responsiveness of Airways in Patients with Obstructive Airway Disease

  • Text
  • PDF
Abstract

Inhalation of aerosols of citric acid, histamine phosphate, or carbon dust, or air cooled to - 20°C or rapid respiratory maneuvers (inspiration or expiration) results in an increase in airway resistance in some patients with asthma or bronchitis. It has been shown previously in animals that stimulation of cough receptors results in bronchoconstriction through efferent cholinergic pathways. In the patients studied, the administration of atropine sulfate, which would block such pathways, abolished the bronchoconstrictor effects of all the stimuli except large doses of histamine, which may exert a direct effect on airway smooth muscle. These data suggest that sensitized cough receptors may be involved in triggering reflex airway constriction in such patients.

Authors

B. G. Simonsson, F. M. Jacobs, J. A. Nadel

×

Total citations by year

Year: 2025 2023 2022 2021 2020 2019 2016 2014 2013 2012 2011 2010 2009 2008 2007 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980 1979 1978 1977 1976 1975 1974 1973 1972 1971 1970 1969 1968 Total
Citations: 1 2 2 1 1 2 1 4 1 3 3 1 3 1 1 1 1 2 1 3 2 2 3 3 2 4 5 2 3 5 4 8 7 7 11 10 12 19 11 8 7 19 5 10 9 9 5 4 4 2 6 3 1 247
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (247)

Title and authors Publication Year
Smartphone-based health monitoring in India: Data collection and evaluation for pulse rate estimation
Shetty A, Narasimhamurthy SS, Nataraj K, Prabhu SM, Jagadeesh N, Katre K, Kumar S, Kapoor N, Haladi SP, Gulati S
Journal of Family Medicine and Primary Care 2025
Development and clinical validation of Swaasa AI platform for screening and prioritization of pulmonary TB.
Yellapu GD, Rudraraju G, Sripada NR, Mamidgi B, Jalukuru C, Firmal P, Yechuri V, Varanasi S, Peddireddi VS, Bhimarasetty DM, Kanisetti S, Joshi N, Mohapatra P, Pamarthi K
Scientific Reports 2023
Screening COVID-19 by Swaasa AI platform using cough sounds: a cross-sectional study.
Pentakota P, Rudraraju G, Sripada NR, Mamidgi B, Gottipulla C, Jalukuru C, Palreddy SD, Bhoge NKR, Firmal P, Yechuri V, Jain M, Peddireddi VS, Bhimarasetty DM, Sreenivas S, Prasad K KL, Joshi N, Vijayan S, Turaga S, Avasarala V
Scientific Reports 2023
Insulin increases sensory nerve density and reflex bronchoconstriction in obese mice
Gina N Calco, Jessica Maung, David Jacoby, Allison Fryer, Zhenying Nie
JCI Insight 2022
Cigarette Smoke Particle-Induced Lung Injury and Iron Homeostasis.
Ghio AJ, Pavlisko EN, Roggli VL, Todd NW, Sangani RG
International journal of chronic obstructive pulmonary disease 2022
Automatic cough classification for tuberculosis screening in a real-world environment.
Pahar M, Klopper M, Reeve B, Warren R, Theron G, Niesler T
Physiological Measurement 2021
Synthesized atropine nanoparticles ameliorate airway hyperreactivity and remodeling in a murine model of chronic asthma
P Chattopadhyay, MP Pathak, P Patowary, S Chakrabarti, D Goyary, S Karmakar, SK Dwivedi
Journal of drug delivery science and technology 2020
Real-world heart rate norms in the Health eHeart study
R Avram, GH Tison, K Aschbacher, P Kuhar, E Vittinghoff, M Butzner, R Runge, N Wu, MJ Pletcher, GM Marcus, J Olgin
2019
A systematic review of methods of citric acid cough reflex testing
E Wallace, EG Hernandez, A Ang, S Hiew, P Macrae
Pulmonary Pharmacology & Therapeutics 2019
Asthma as a disruption in iron homeostasis
AJ Ghio
BioMetals 2016
Update: the search for the human cough receptor.
McGarvey L
Lung 2014
Comprehensive Physiology
SN Cheuvront, RW Kenefick
Comprehensive Physiology 2014
Increased bronchial parasympathetic tone in elite cross-country and biathlon skiers: a randomised crossover study
J Stang, M Couto, KH Carlsen, T Stensrud
British journal of sports medicine 2014
Anatomy and Neurophysiology of Cough: CHEST Guideline and Expert Panel Report
BJ Canning, AB Chang, DC Bolser, JA Smith, SB Mazzone, L McGarvey, TM Adams, KW Altman, AF Barker, SS Birring, F Blackhall, DC Bolser, LP Boulet, SS Braman, C Brightling, P Callahan-Lyon, B Canning, AB Chang, R Coeytaux, T Cowley, P Davenport, RL Diekemper, S Ebihara, AA el Solh, P Escalante, A Feinstein, SK Field, D Fisher, CT French, P Gibson, P Gold, C Grant, SM Harding, A Harnden, AT Hill, RS Irwin, PJ Kahrilas, KA Keogh, AP Lane, SZ Lewis, K Lim, MA Malesker, P Mazzone, S Mazzone, L McGarvey, A Molasiotis, MH Murad, P Newcombe, HQ Nguyen, J Oppenheimer, D Prezant, T Pringsheim, MI Restrepo, M Rosen, B Rubin, JH Ryu, J Smith, SM Tarlo, RB Turner, A Vertigan, G Wang, K Weir
Chest 2014
Acid-sensing by airway afferent nerves
LY Lee, Q Gu, F Xu, JL Hong
Pulmonary Pharmacology & Therapeutics 2013
Autonomic modulations in patients with bronchial asthma based on short-term heart rate variability
MF Lutfi
Lung India : official organ of Indian Chest Society 2012
A Brief History of Airway Smooth Muscle’s Role in Airway Hyperresponsiveness
CD Pascoe, L Wang, HT Syyong, PD Paré
Journal of allergy 2012
Regular treatment with formoterol for chronic asthma: serious adverse events
CJ Cates, MJ Cates
Cochrane Database of Systematic Reviews 2012
Formulations for Pulmonary Administration of Anticancer Agents to Treat Lung Malignancies
TC Carvalho, SR Carvalho, JT McConville
Journal of Aerosol Medicine and Pulmonary Drug Delivery 2011
Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee
Annual Reports in Medicinal Chemistry Volume 46 2011
Airway irritation and cough evoked by acid: from human to ion channel
Q Gu, LY Lee
Current Opinion in Pharmacology 2011
Cochrane Database of Systematic Reviews: Reviews
N Shafiq, M Singh, S Kaur, P Khosla, S Malhotra, N Shafiq
Cochrane Database of Systematic Reviews: Reviews 2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Frontiers in Neuroscience
K Panickar, S Bhathena
Fat Detection 2009
Middleton's Allergy: Principles and Practice
RP Schleimer
Middleton's Allergy: Principles and Practice 2009
Regular treatment with salmeterol for chronic asthma: serious adverse events
CJ Cates, MJ Cates
Cochrane Database of Systematic Reviews 2008
Role of TRPV receptors in respiratory diseases
Y Jia, LY Lee
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2007
A centennial history of research on asthma pathogenesis
MJ Walter, MJ Holtzman
American journal of respiratory cell and molecular biology 2005
Facial Cooling Enhances Exercise-Induced Bronchoconstriction in Asthmatic Children:
M Zeitoun, B Wilk, A Matsuzaka, BH KnPfli, BA Wilson, O Bar-Or
Medicine and Science in Sports and Exercise 2004
The role of mast cells in asthma
JA Boyce
Prostaglandins, Leukotrienes and Essential Fatty Acids 2003
The Three-Dimensional Distribution of Nerves Along the Entire Intrapulmonary Airway Tree of the Adult Rat and the Anatomical Relationship Between Nerves and Neuroepithelial Bodies
SD Larson, ES Schelegle, DM Hyde, CG Plopper
American journal of respiratory cell and molecular biology 2003
Forced Expiratory Time and Bronchial Hyperresponsiveness to Methacholine
MF Goldstein, BA Veza, A Lauf-Goldstein, DJ Dvorin, EH Dunsky, GA Belecanech
Journal of Asthma 2002
Histopathology of the airway epithelium in an experimental dual-phase model of bronchial asthma
Y Tohda, H Kubo, M Ito, M Fukuoka, S Nakajima
Clinical & Experimental Allergy 2001
Bradykinin activates airway parasympathetic ganglion neurons by inhibiting M-currents
T Mochidome, H Ishibashi, K Takahama
Neuroscience 2001
Afferent properties and reflex functions of bronchopulmonary C-fibers
LY Lee, TE Pisarri
Respiration Physiology 2001
Ullmann's Encyclopedia of Industrial Chemistry
J Sandow, E Scheiffele, M Haring, G Neef, K Prezewowsky, U Stache
Ullmann's Encyclopedia of Industrial Chemistry 2000
Capsaicin responsiveness and cough in asthma and chronic obstructive pulmonary disease
MJ Doherty, R Mister, MG Pearson, PM Calverley
Thorax 2000
Gastroesophageal Reflux Disease and Airway Disease: The Role of Nerves and the Potential Influence of Gastroesophageal Reflux Disease
B Canning
Gastroesophageal Reflux Disease and Airway Disease: The Role of Nerves and the Potential Influence of Gastroesophageal Reflux Disease 1999
New and Exploratory Therapeutic Agents for Asthma
R Djukanovi_
New and Exploratory Therapeutic Agents for Asthma 1999
Acetylcholine modulation of high-voltage-activated calcium channels in the neurones acutely dissociated from rat paratracheal ganglia
Y Murai, H Ishibashi, N Akaike, Y Ito
British Journal of Pharmacology 1998
Airway cough sensitivity to inhaled capsaicin and bronchial responsiveness to methacholine in asthmatic and bronchitic subjects
M FUJIMURA, Y KAMIO, T HASHIMOTO, T MATSUDA
Respirology 1998
Managing Cough as a Defense Mechanism and as a Symptom
RS Irwin, LP Boulet, MM Cloutier, R Fuller, PM Gold, V Hoffstein, AJ Ing, FD McCool, P OByrne, RH Poe, UB Prakash, MR Pratter, BK Rubin
Chest 1998
The effects of a specific tachykinin receptor antagonist FK-224 on ozone-induced airway hyperresponsiveness and inflammation
H Aizawa, H Koto, H Nakano, H Inoue, K Matsumoto, S Takata, M Shigyo, N Hara
Respirology 1997
Effects of the combination of skin cooling and hyperpnea of frigid air in asthmatic and normal subjects
JS McDonald, J Nelson, KA Lenner, ML McLane, ER McFadden
Journal of applied physiology 1997
Relationship between bronchial reversibility and tracheobronchial clearance in patients with chronic bronchitis
M Moretti, MT Lopez-Vidriero, D Pavia, SW Clarke
Thorax 1997
Brief Reversible Bronchospasm Resulting from Bichromate Exposure
T Shirakawa, K Morimoto
Archives of Environmental Health An International Journal 1996
Oxygen radicals in the nonvagal component of noncholinergic airway constriction
HQ Zhang, HH Tai, YL Lai
Respiration Physiology 1996
Contribution of a cholinergic reflex mechanism to allergen-induced bronchial hyperreactivity in permanently instrumented, unrestrained guinea-pigs
RE Santing, Y Pasman, CG Olymulder, AF Roffel, H Meurs, J Zaagsma
British Journal of Pharmacology 1995
Effects of capsazepine against capsaicin- and proton-evoked excitation of single airway C-fibres and vagus nerve from the guinea-pig
AJ Fox, L Urban, PJ Barnes, A Dray
Neuroscience 1995
Effect of BAY u3405, a thromboxane A2 receptor antagonist, on neuro-effector transmission in canine tracheal tissue
H Aizawa, S Takata, M Shigyo, K Matsumoto, H Koto, H Inoue, N Hara
Prostaglandins, Leukotrienes and Essential Fatty Acids 1995
Relation Between Bronchial and Cardiac Vagal Tone in Healthy Humans
I Horváth, K Argay, I Herjavecz, M Rollai
Chest 1995
Effects of thromboxane A2 agonist STA2 on rapidly adapting pulmonary stretch receptors in vagotomized rabbits
S Matsumoto, S Takano, N Nakahata, T Shimizu
Lung 1994
Airways Smooth Muscle
D Raeburn, MA Giembycz
1994
Airways Smooth Muscle: Development, and Regulation of Contractility
D Raeburn, MA Giembycz
1994
VIP antagonists enhance excitatory cholinergic neurotransmission in the human airway
H Aizawa, H Inoue, M Shigyo, S Takata, H Koto, K Matsumoto, N Hara
Lung 1994
Airway epithelial cells modulate cholinergic neurotransmission in dog trachea.
Aizawa H, Matsumoto K, Shigyo M, Inoue H, Koto H, Takata S, Hara N
Lung 1994
Roles of eosinophils and catecholamines in pathophysiology of exercise-induced asthma
H Tsuda, A Tsuda, M Ito, M Nambu, M Mayumi, H Mikawa
Pediatric Allergy and Immunology 1993
Corticosteroid Withdrawal Restores Responses to Calcium Chelators and Enhances Cholinergic Responsiveness
KS Lindeman, CA Hirshman
American journal of respiratory and critical care medicine 1993
Effects of methacholine induced bronchoconstriction and procaterol induced bronchodilation on cough receptor sensitivity to inhaled capsaicin and tartaric acid
M Fujimura, S Sakamoto, Y Kamio, T Matsuda
Thorax 1992
Das cholinerge System der Atemwege
F Kummer
1992
Swimming and Asthma: Benefits and Deleterious Effects
O Bar-Or, O Inbar
Sports Medicine 1992
The effect of inhaled ipratropium bromide alone and in combination with oral terfenadine on bronchoconstriction provoked by adenosine 5′-monophosphate and histamine in asthma
R Polosa, GD Phillips, K Rajakulasingam, ST Holgate
Journal of Allergy and Clinical Immunology 1991
Effect of Short-Term Exposure to Low Levels of SO<sub>2</sub> and NO<sub> <i>x</i> </sub> on Pulmonary Function and Methacholine and Allergen Bronchial Sensitivities in Asthmatic Children
JL Huang, SY Wang, KH Hsieh
Archives of Environmental Health An International Journal 1991
Effect of steroid hormones on muscarinic receptors of bronchial smooth muscle
BM Nabishah, PB Morat, BA Kadir, BA Khalid
General Pharmacology: The Vascular System 1991
Citric acid cough threshold and airway responsiveness in asthmatic patients and smokers with chronic airflow obstruction
B Auffarth, JG de Monchy, TW van der Mark, DS Postma, GH Koeter
Thorax 1991
New Perspectives in Histamine Research
H Timmerman, H van der Goot
1991
Neural control of airway function: New perspectives
PJ Barnes
Molecular Aspects of Medicine 1990
Cough-variant asthma in children and adults: case reports and review
ES Pender, CV Pollack
The Journal of Emergency Medicine 1990
Relationship Between Airways Responsiveness and the Development of Chronic Obstructive Pulmonary Disease
JA Dosman, SR Gomez, C Zhou
Medical Clinics of North America 1990
Airways Responses to Ipratropium Bromide Do Not Vary with Time in Asthmatic Subjects
E Ihre, K Larsson
Chest 1990
Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs
H Kohrogi, JA Nadel, B Malfroy, C Gorman, R Bridenbaugh, JS Patton, DB Borson
Journal of Clinical Investigation 1989
Histamine and its antagonists in asthma
P Rafferty, ST Holgate
Journal of Allergy and Clinical Immunology 1989
Afferent pathways involved in reflex regulation of airway smooth muscle
HM Coleridge, JC Coleridge, HD Schultz
Pharmacology & Therapeutics 1989
The MVV/FEV1 Ratio in Normal and Asthmatic Subjects
RD Fairshter, A Carilli, A Soriano, J Lin, U Pai
Chest 1989
Effect of Azelastine, an Antiasthmatic Drug, on Bronchial Responsiveness in Patients with Bronchial Asthma
M Iwata, M Tano, S Sugiyama, F Taki, T Satake
Chest 1989
Airway Smooth Muscle in Health and Disease
RF Coburn
1989
Effect of Oxitropium Bromide (Ba253) on Increased Airway Resistance Induced by Various Agonists and Antigen in the Guinea Pig
SW KOHNO, H HASHII, K OGINO, H YAMAMURA, K OHATA
The Japanese Journal of Pharmacology 1989
Response to Bronchodilators
C Shim
Clinics in Chest Medicine 1989
Neutral endopeptidase inhibitors potentiate substance P- and capsaicin-induced cough in awake guinea pigs
H Kohrogi, PD Graf, K Sekizawa, DB Borson, JA Nadel
Journal of Clinical Investigation 1988
A possible role of airway epithelium in modulating hyperresponsiveness
H Aizawa, N Miyazaki, N Shigematsu, M Tomooka
British Journal of Pharmacology 1988
Chronic asthma and improvement with relaxation induced by hypnotherapy
JB Morrison
Journal of the Royal Society of Medicine 1988
In vivo and in vitro studies on cold-induced airway response in normal and sensitized rabbits
M Badier, P Barthelémy, M Soler, Y Jammes
Respiration Physiology 1988
Reciprocal action of pulmonary vagal afferents on tracheal smooth muscle tension in dogs
AM Roberts, HM Coleridge, JC Coleridge
Respiration Physiology 1988
Methacholine Bronchial Reactivity Testing in Patients with Chronic Congestive Heart Failure
PQ Eichacker, MJ Seidelman, MS Rothstein, T Lejemtel
Chest 1988
Lack of effect from a single cigarette challenge on bronchial responsiveness in healthy non-smoking subjects
S Suzuki, F Sano, J Suzuki, H Numata, T Okubo
Thorax 1988
Personal Experiences: Effect of Respiratory Exercises on Asthma the Pink City Lung Exerciser
V Singh
Journal of Asthma 1987
Inhibition of artificially induced cough in man by bronchodilators
R Lowry, T Higenbottam, T Johnson, D Godden
British Journal of Clinical Pharmacology 1987
Characterization of cholinergic muscarinic receptors in cow tracheal muscle membranes
KG Rothberg, PL Morr, JS Douglas
Biochemical Pharmacology 1987
Histamine receptors and pulmonary epithelial permeability
TB Chan, N Eiser, D Shelton, PJ Rees
British Journal of Diseases of the Chest 1987
Reactions to Bronchoconstrictor Drugs
C Shim, MH Williams
Chest 1987
Cough: Differential Diagnosis and Treatment
SS Braman, WM Corrao
Clinics in Chest Medicine 1987
Bupivicaine-fentanyl epidural analgesia for a parturient in status asthmaticus
D Younker, R Clark, J Tessem, TH Joyce, M Kubicek
Canadian Journal of Anesthesia/Journal canadien d'anesthésie 1987
The architecture of nerves and ganglia of the ferret trachea as revealed by acetylcholinesterase histochemistry
DG Baker, DM McDonald, CB Basbaum, RA Mitchell
The Journal of Comparative Neurology 1986
The role of vagus nerve on histamine- and acetylcholine-induced bronchoconstriction (experiments on cats)
I Zimmermann, WT Ulmer
Research in Experimental Medicine 1986
Cold air provocation of airway hyperreactivity in patients with cystic fibrosis
LL Darga, LA Eason, G Polgar, DM Zach
Pediatric Pulmonology 1986
PROSTAGLANDIN D2 (PGD2) POTENTIATES CHOLINERGIC RESPONSIVENESS IN GUINEA-PIG TRACHEA
C Omini, G Brunelli, L Daffonchio, C Mapp, L Fabbri, F Berti
Autonomic and Autacoid Pharmacology 1986
Bronchial responsiveness to methacholine during airway cooling in normal subjects
S Suzuki, M Ishii, J Sasaki, T Takishima
Clinical & Experimental Allergy 1986
Cholinergic and neurogenic mechanisms in obstructive airways disease
ER Bleecker
The American Journal of Medicine 1986
Trachea noise biofeedback device to help reduce bronchospasm in asthmatics
MJ Mussell
Journal of Biomedical Engineering 1986
Peripheral Airways Function and Nonspecific Airways Reactivity in Cigarette Smokers
JA Dosman, K Bergstrom, K Clark, S Khaladkar
Chest 1986
Assessment of the relative safety of the beta-blockers ICI 141,292 and atenolol in patients with bronchial asthma
S Groth, P Tnnesen, M Asted, H Dirksen, PG Srensen
European Journal of Clinical Pharmacology 1986
Die Praxis der Sportmedizin in der Kinderheilkunde
O Bar-Or, G Rost, R Rost
1986
Parasympathetic Motor Pathways to the Trachea: Recent Morphologic and Electrophysiologic Studies
DG Baker
Clinics in Chest Medicine 1986
Pulmonary responsiveness to methacholine and disodium hexachloroplatinate (Na2PtCl6) aerosols in cynomolgus monkeys (Macaca fascicularis)
RE Biagini, WJ Moorman, TR Lewis, IL Bernstein
Toxicology and Applied Pharmacology 1985
Committee Report: Guidelines for Standardization of Bronchial Challenges with (Nonspecific) Bronchoconstricting Agents
NM Eiser, KF Kerrebijn, PH Quanjer
Journal of Asthma 1985
Beat-to-Beat Variation of the Heart Rate in Children with Allergic Asthma
K Tokuyama, A Morikawa, M Mitsuhashi, H Mochizuki, K Tajima, T Kuroume
Journal of Asthma 1985
Increased Bronchial Hypersensitivity after Early and Late Bronchial Reactions Provoked by Allergen Inhalation
L Machado
Allergy 1985
Effects of aerosolized histamine and carbachol in the conscious horse
KB Mirbahar, WN McDonell, W Bignell, P Eyre
Canadian journal of comparative medicine. Revue canadienne de médecine comparée 1985
Progress in Medicinal Chemistry
JR Brown, SH Imam
Progress in Medicinal Chemistry 1985
Anticholinergic drugs in the treatment of airways disease
JS Mann, CF George
British Journal of Diseases of the Chest 1985
Pulmonary Function Measurement in the Industrial Setting
M Chan-Yeung, S Lam, D Enarson
Chest 1985
Airway responsiveness to histamine in man: effect of atropine on in vivo and in vitro comparison
JA Roberts, IW Rodger, NC Thomson
Thorax 1985
Absence of refractoriness in asthmatic subjects after exercise with warm, humid inspirate
AG Hahn, SG Nogrady, GR Burton, AR Morton
Thorax 1985
The correlation between allergen, acetylcholine and histamine-induced bronchoconstriction
I Zimmermann, AA de Almeida, WT Ulmer
Agents and Actions 1984
Changes in volume of trapped gas in chronic bronchitis and in asthma after inhalation of fenoterol
J Arnved, S Groth, H Dirksen
Lung 1984
Variable inhibition of histamine-induced bronchoconstriction by atropine in subjects with asthma
D Sheppard, J Epstein, BE Skoogh, RA Bethel, JA Nadel, HA Boushey
Journal of Allergy and Clinical Immunology 1984
Bronchodilatory effect of warm air inhalation during quiet breathing
JE Carbone, JJ Marini
The Western journal of medicine 1984
The influence of pretreatment with prostaglandin F2α on bronchial sensitivity to inhaled histamine and methacholine in normal subjects
RW Heaton, AF Henderson, LS Dunlop, JF Costello
British Journal of Diseases of the Chest 1984
Development of Anti-Asthma Drugs
N Eiser
Development of Anti-Asthma Drugs 1984
Acute airway changes in induced by coughing
PJ Rees, TJ Clark
British Journal of Diseases of the Chest 1984
Cold Air as a Bronchial Provocation Technique
RW Heaton, AF Henderson, JF Costello
Chest 1984
Potassium tolerance and bronchial reactivity in asthmatic and nonasthmatic atopic subjects
L Marazzini, R Cavestri, B Mastropasqua, M Bozzoni, M Pacetti, E Longhini
Journal of Clinical Immunology 1984
Ipratropium bromide in patients with nocturnal asthma
ID Cox, DT Hughes, KA McDonnell
Postgraduate medical journal 1984
Comparison of airway responses following tracheal or esophageal acidification in the cat
DN Tuchman, JT Boyle, AI Pack, J Scwartz, M Kokonos, AR Spitzer, S Cohen
Gastroenterology 1984
Analysis of the Vagal Reflex Tracheal Constriction in the Dog
T HOSOKAWA, K GOTO, J KAMEI, K OHTANI, M MISAWA, S YANAURA
The Japanese Journal of Pharmacology 1984
Functional depression of H2 histamine receptors in sheep with experimental allergic asthma
T Ahmed, JP Krainson, LD Yerger
Journal of Allergy and Clinical Immunology 1983
The effects of lidocaine and hexamethonium on prostaglandin F2-alpha- and histamine-induced bronchoconstriction in sulfur dioxide-treated beagle dogs
PE Malo, RL Griffin
Drug Development Research 1983
Ancillary Medical Therapy: Help or Hindrance
JE Selcow
Journal of Asthma 1983
Histamine release into cracheal lumen and bronchial reactivity
I Zimmermann, AA de Almeida, WT Ulmer, SH Park
Research in Experimental Medicine 1983
Changes in the bronchial reactivity of dogs caused by exposure to sulphur dioxide
M Dixon, DM Jackson, IM Richards
The Journal of Physiology 1983
How many blows really make an FEV1, FVC, or PEFR?
MI Ullah, V Cuddihy, KB Saunders, GJ Addis
Thorax 1983
Pathogenesis of asthma: a review
PJ Barnes
Journal of the Royal Society of Medicine 1983
Effects of Smoking on Dynamic Compliance and Respiratory Resistance
S Suzuki, H Sasaki, T Takishima
Archives of Environmental Health An International Journal 1983
Bronchial asthma in adults: Presentation to the emergency department
BE Brenner
The American Journal of Emergency Medicine 1983
The role of histamine and its receptors in the pathogenesis of asthma
J White, NM Eiser
British Journal of Diseases of the Chest 1983
Mechanisms of the temperature effect on airway smooth muscle
JF Souhrada, D Presley, M Souhrada
Respiration Physiology 1983
Partial and Complete Maximum Expiratory Flow-Volume Curves in Asthmatic Patients with Spontaneous Bronchospasm
N Zamel, D Hughes, H Levison, RD Fairshter, AF Gelb
Chest 1983
Inhalation Challenge with Carbachol and Isoproterenol to Predict Bronchospastic Response to Propranolol in COPD
KA Popio, DH Jackson, MJ Utell, AJ Swinburne, RW Hyde
Chest 1983
Pediatric Sports Medicine for the Practitioner
O Bar-Or
1983
Effect of terbutaline sulphate in chronic "allergic" cough
R Ellul-Micallef
BMJ : British Medical Journal 1983
Central Neurone Environment and the Control Systems of Breathing and Circulation
ME Schläfke, WR See, HP Koepchen
1983
Near Fatal Asthma after eating deeply Frozen Ice Cream
A Henderson
Journal of the Royal Army Medical Corps 1983
EFFECTS OF 8-(2-FLUOROETHYL)-3α-HYDROXY-1αH, 5αH-TROPANIUM BROMIDE BENZILATE (Ba598Br) ON ALLERGY- AND DRUG-INDUCED ASTHMAS
S YANAURA, H MIZUNO, K GOTO, J KAMEI, T HOSOKAWA, K OHTANI, M MISAWA
The Japanese Journal of Pharmacology 1983
Exercise-induced asthma
P A Eggleston
Clinical Reviews in Allergy 1983
Effects of exogenous and endogenous histamine on the respiratory system
WT Ulmer, I Zimmermann, AA de Almeida, HS Park
Klinische Wochenschrift 1982
The effects of lidocaine and hexamethonium on prostaglandin F2?- and histamine-induced bronchoconstriction in normal andASCARIS-sensitive dogs
PE Malo, MA Wasserman, RL Griffin
Drug Development Research 1982
NIFEDIPINE INHIBITS DEEP-INSPIRATION-INDUCED BRONCHOCONSTRICTION IN ASTHMATICS
G Rolla, C Bucca, S Polizzi, A Maina, O Giachino, P Salvini
The Lancet 1982
BACTERIOLOGY OF OTITIS MEDIA IN MOZAMBIQUE
A Pisacane, I Ruas
The Lancet 1982
Occupational asthma
D Sheppard
The Western journal of medicine 1982
Pharmacology of Histamine Receptors
P Eyre, N Chand
Pharmacology of Histamine Receptors 1982
The Pathophysiology of Asthma
JC M.D.
Chest 1982
Effect of pH on bronchial response to inhaled histamine
DW Cockcroft, BA Berscheid
Thorax 1982
Immediate response to cigarette smoke
PJ Rees, PJ Chowienczyk, TJ Clark
Thorax 1982
Dual effect of prostaglandin E2 on normal airways smooth muscle in vivo
E Walters, B Davies
Thorax 1982
Combination Bronchodilator Therapy:
GM Shenfield
Drugs 1982
Lung function changes by ethanol inhalation
E Zuskin, A Bouhuys, M Sari
Clinical & Experimental Allergy 1981
The effect of ipratropium and fenoterol on methacholine- and histamine-induced bronchoconstriction
J Bandouvakis, A Cartier, R Roberts, G Ryan, FE Hargreave
British Journal of Diseases of the Chest 1981
The direct effect of temperature on airway smooth muscle
M Souhrada, JF Souhrada
Respiration Physiology 1981
Physical Activity and the Asthmatic
AR Morton, KD Fitch, AG Hahn
The Physician and Sportsmedicine 1981
The Effects of Oral Doses of Theophylline and Fenoterol on Exercise-Induced Asthma
PA Eggleston, PP Beasley, RT Kindley
Chest 1981
Effects of Inhaled Atropine in Chronic Bronchitis
TJ Witek, NL Dean, EN Schachter
Chest 1981
Airway Responsiveness and Chronic Airway Obstruction
CH Fanta, RH Ingram
Medical Clinics of North America 1981
Methods in Clinical Pharmacology—Respiratory System
JB Howell, AE Tattersfield
1981
Histamine-Induced Bronchospasm
B Hegardt, O Löwhagen, N Svedmyr
Allergy 1980
Comparison of bronchial reactivity to histamine and methacholine in asthmatics
CM Salome, RE Schoeffel, AJ Woolcock
Clinical & Experimental Allergy 1980
A non-pharmacologic approach to the treatment of exercise-induced bronchospasm
EN Schachter, M Lee, H Gerhard, S Brown
The Yale journal of biology and medicine 1980
A MODEL OF IRRITANT-INDUCED BRONCHOCONSTRICTION IN THE SPONTANEOUSLY BREATHING GUINEA-PIG
C Allott, D Evans, P Marshall
British Journal of Pharmacology 1980
The Effect of Atropine Inhalation in “Irreversible” Chronic Bronchitis
JJ Marini, S Lakshminarayan
Chest 1980
Verhandlungen der Deutschen Gesellschaft für innere Medizin
B Schlegel
1980
Cholinergic blockade in the prevention of exercise-induced asthma
JP Hartley, BH Davies
Thorax 1980
Methods of study of airway smooth muscle and its physiology
HL Hahn, JA Nadel
Pharmacology & Therapeutics 1979
Severe Asthmatic Reaction During Long-Term Treatment with Disodium Cromoglycate Powder Inhalations
J Serup
Acta Medica Scandinavica 1979
A controlled study on the preventive effect of ketotifen, an antiallergic agent, on methacholine-induced bronchoconstriction in asthmatics
K Mattson, H Poppius, R Hurme
Clinical & Experimental Allergy 1979
Lung volumes
S Freedman
British Journal of Clinical Pharmacology 1979
Assessing change in airway calibre--measurement of airway resistance
AE Tattersfield, IM Keeping
British Journal of Clinical Pharmacology 1979
Bronchoconstriction in potroom workers
M Sarić, E Zuskin, M Gomzi
British journal of industrial medicine 1979
Assessment of changes in airway calibre I. Tests of forced expiration
NB Pride
British Journal of Clinical Pharmacology 1979
Bronchial provocation tests
MK Benson
British Journal of Clinical Pharmacology 1979
Assessing change in airway calibre-measurement of airway resistance
AE Tattersfield, IM Keeping
British Journal of Clinical Pharmacology 1979
Chronic Cough as the Sole Presenting Manifestation of Bronchial Asthma
WM Corrao, SS Braman, RS Irwin
New England Journal of Medicine 1979
Temperature dependence of tracheal smooth muscle response to isoproterenol
D Downing, RC Kolbeck, JE Holl, ED Bransome, WA Speir
Life Sciences 1979
Exercise-Induced Asthma: Observations on the Initiating Stimulus
HL Bleich, MJ Moore, ER McFadden, RH Ingram
New England Journal of Medicine 1979
Effects of Breathing Warm Humidified Air on Bronchoconstriction Induced by Body Cooling and by Inhalation of Methacholine
DJ Horton, WY Chen
Chest 1979
Effect of Ammonia on Nasal Resistance in Atopic and Nonatopic Subjects
JA McLean, KP Mathews, WR Solomon, PR Brayton, NK Bayne
The Annals of otology, rhinology, and laryngology 1979
Cellular, Molecular, and Clinical Aspects of Allergic Disorders
S Gupta, RA Good
1979
Comparison of pirbuterol and pirbuterol and hydroxyzine in patients with reversible airway obstruction
H Poppius, H Lehti, B Stenius-Aarniala
European Journal of Clinical Pharmacology 1979
The role of adrenoceptors in bronchial asthma
K R Patel
Journal of the Royal College of Physicians of London 1979
Mechanisms of the bronchoconstrictor effects of deep inspiration in asthmatic patients
P Gayrard, J Orehek, C Grimaud, J Charpin
Thorax 1979
Bronchitis · Asthma Emphysem
WT Ulmer, H Bachofen, H Fabel, R Ferlinz, E Fuchs, W Hartung, P Hilpert, E Kammler, B Rasche, HS Stender
1979
PROPRANOLOL ABUSE OR PERFORMER'S MATURATION?
C Swartz
The Lancet 1978
SHOULD ASTHMATIC PATIENTS LAUGH?
P Gayrard
The Lancet 1978
Drugs in the treatment of asthma
N Svedmyr, BG Simonsson
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology 1978
Changes of airway smooth muscle in experimental asthma
JF Souhrada
Respiration Physiology 1978
Influence of Tracheal Muscular Tone on the Initiation of Cough Reflex
S Yanaura, T Hosokawa, H Kitagawa, Y Yamatake
The Japanese Journal of Pharmacology 1978
The Frequency and Importance of Bronchial Hyperreactivity in Patients With Allergic and Non-Allergic Rhinitis
A Dziedziczko, R Gniazdowski
Acta Oto-laryngologica 1977
Effect of deep inspiration on airway conductance in subjects with allergic rhinitis and allergic asthma
JE Fish, VI Peterman, DW Cugell
Journal of Allergy and Clinical Immunology 1977
Asthma induced by sulphur dioxide, benzoate and tartrazine contained in orange drinks
BJ Freedman
Clinical & Experimental Allergy 1977
Protective effect of drugs on histamine-induced asthma
DW Cockcroft, DN Killian, JJ Mellon, FE Hargreave
Thorax 1977
Bronchoconstrictor drugs
BG Simonsson, N Svedmyr
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology 1977
Enhancement of Exercise-Induced Asthma by Cold Air
RH Strauss, ER McFadden, RH Ingram, JJ Jaeger, DR Stearns
New England Journal of Medicine 1977
Some experimental models of acute asthma
J G Widdicombe
Journal of the Royal College of Physicians of London 1977
Bronchial secretion from normal human airways after inhalation of prostaglandin F2alpha, acetylcholine, histamine, and citric acid
MT Lopez-Vidriero, I Das, AP Smith, R Picot, L Reid
Thorax 1977
Time course of bronchoconstrictive response in asthmatic subjects to reduced temperature
JM Ramsey
Thorax 1977
INVOLVEMENT OF HISTAMINE H1- AND H2-RECEPTORS IN INDUCED ASTHMAS IN DOGS
Y YAMATAKE, S SASAGAWA, S YANAURA, N KOBAYASHI
The Japanese Journal of Pharmacology 1977
Effect of short-term, low-level nitrogen dioxide exposure on bronchial sensitivity of asthmatic patients
J Orehek, JP Massari, P Gayrard, C Grimaud, J Charpin
Journal of Clinical Investigation 1976
Hypersensitivity to acetylsalicylic acid (ASA) and tartrazine in patients with asthma
BS Stenius, M Lemola
Clinical & Experimental Allergy 1976
Factors in allergen-induced asthma: relevance of the intensity of the airways allergic reaction and non-specific bronchial reactivity
D Killian, DW Cockcroft, FE Hargreave, J Dolovich
Clinical & Experimental Allergy 1976
Interaction between bronchoconstrictor stimuli on human airway smooth muscle
C Mitchell, A Bouhuys
The Yale journal of biology and medicine 1976
Climate and Environment Change in Patients With Chronic Airway Obstruction: A Pilot Study on the Effects on Lung Function
BE Skoogh, BG Simonsson, AG Berggren, Z Bergstrouml;m, M Johansson
Archives of Environmental Health An International Journal 1976
Fiberoptic Bronchoscopy in Bronchial Asthma
SA Sahn, C Scoggin
Chest 1976
Leistungsbegrenzung von seiten der Lunge
WT Ulmer
1976
Therapeutic value of anticholinergic agents in chronic obstructive pulmonary diseases
E Vastag, L Nagy, G Miskovits
European Journal of Clinical Pharmacology 1976
The relation of urban atmospheric variables to asthmatic bronchoconstriction
JM Ramsey
Bulletin of Environmental Contamination and Toxicology 1976
Effect of sodium cromoglycate on asthmatic reactions to environmental temperature changes
AB Breslin, J Pepys
Clinical & Experimental Allergy 1975
Effect of maximal respiratory manoeuvres on bronchial sensitivity of asthmatic patients as compared to normal people
J Orehek, P Gayrard, C Grimaud, J Charpin
British medical journal 1975
The effect of prostaglandin F2β on expiratory flow rates
P Hamosh, AM da Silva
Prostaglandins 1975
Bronchial hyperreactivity
MK Benson
British Journal of Diseases of the Chest 1975
Exertional Dyspnea and Cough as Preludes to Acute Attacks of Bronchial Asthma
ER Fadden
New England Journal of Medicine 1975
Effect of atropine on sputum production
MT Lopez-Vidriero, J Costello, TJ Clark, I Das, EE Keal, L Reid
Thorax 1975
Beta-adrenergic function in airways of healthy and asthmatic subjects
P Gayrard, J Orehek, C Grimaud, J Charpin
Thorax 1975
The Role of Bronchoconstriction in Cough Reflex
S Yanaura, T Nishimura, M Sakamoto, T Sasao
The Japanese Journal of Pharmacology 1975
Unusual side effects during disodium cromoglycate (intal) therapy in a case of bronchial asthma (case report)
J Müller, J Kowalski
Lung 1975
BRONCHIAL REACTIVITY TO INHALED HISTAMINE IN ASTHMATIC PATIENTS, BEFORE AND AFTER ADMINISTRATION OF ATROPINE, PHENTOLAMINE OR DISODIUM CROMOGLYCATE
KO Pegelow
Allergy 1974
PARASYMPATHETIC NERVOUS CONTROL OF AIRWAY SMOOTH MUSCLE
JA Nadel
Annals of the New York Academy of Sciences 1974
Recent advances in the pathophysiology of asthma
AF Wilson, SP Galant
The Western journal of medicine 1974
Asthma: Current Concepts
H Levison, C Collins-Williams, AC Bryan, BJ Reilly, RP Orange
Pediatric Clinics of North America 1974
Immunological Aspects of Allergy and Allergic Diseases
E Rajka, S Korossy
1974
Normal Airways Conductance at Different Lung Volumes
BE Skoogh
Scandinavian Journal of Clinical & Laboratory Investigation 1973
Bronchial hyperreactivity to prostaglandin F 2 and histamine in patients with asthma
AA Mathé, P Hedqvist, A Holmgren, N Svanborg
British medical journal 1973
Sensory Irritation by Airborne Chemicals
Y Alarie
Critical Reviews in Toxicology 1973
Bronchopulmonary Diseases: Immunologic Perspectives
DA Mathison, DD Stevenson
Postgraduate Medicine 1973
VALEUR DU TEST DE PROVOCATION PAR ALLERGENES INHALES DANS L'ASTHME
P Gayrard, J Orehek, C Boutin, J Charpin
Allergy 1972
Where is the allergic reaction in ragweed asthma? *1II. Demonstration of ragweed antigen in airborne particles smaller than pollen
WW Busse, CE Reed, JH Hoehne
Journal of Allergy and Clinical Immunology 1972
Exercise-induced airways constriction
BG Simonsson, BE Skoogh, B Ekström-Jodal
Thorax 1972
Medical Hazards of Aerosols: First of Two Parts
IL Bernstein
Postgraduate Medicine 1972
Cough syncope
AM Jain
The Indian Journal of Pediatrics 1971
Mechanism of bronchoconstriction due to beta adrenergic blockade
MH Grieco, RN Pierson
Journal of Allergy and Clinical Immunology 1971
Respiratory mechanics and dust exposure in byssinosis
A Bouhuys, KP van de Woestijne
Journal of Clinical Investigation 1970
Acute massive pulmonary collapse
NJ Coroneos, J Lawrence, TA Torda
Anaesthesia 1970
Cough syncope in children with asthma
RM Katz
The Journal of Pediatrics 1970
Cardiopulmonary effects of methacholine in asthmatic and normal subjects
MH Grieco, RN Pierson
Journal of Allergy 1970
The Effect of Cold Air Inhalation on Respiratory Gas Exchange During Exercise in Patients With Chronic Obstructive Pulmonary Disease
YC Hsieh, R Frayser, JC Ross
Chest 1970
Psychosomatic Aspects of Respiratory Disorders
M Stein, TJ Luparello
Postgraduate Medicine 1970
Maximum expiratory flow rates in induced bronchoconstriction in man
A Bouhuys, VR Hunt, BM Kim, A Zapletal
Journal of Clinical Investigation 1969
Asthmatic Hyperresponsiveness
EM Heimlich
Pediatric Clinics of North America 1969
Psychosomatic Study and Treatment of Asthmatic Children
CJ Falliers
Pediatric Clinics of North America 1969
THE CHANGING PATTERN OF MORTALITY FROM ASTHMA IN AUSTRALIA: 2. MORTALITY AND MODERN THERAPY
B Gandevia
The Medical Journal of Australia 1968

← Previous 1 2 3 … 9 10 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Referenced in 29 patents
Referenced in 1 clinical guideline sources
25 readers on Mendeley
See more details