Intrarenal Distribution of Blood Flow in the Transplanted Dog Kidney: Effect of Denervation and Rejection

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Abstract

Serial measurements of intrarenal distribution of blood flow have been recorded in anesthetized dogs with the 133xenon “washout” technique. The results showed that normal kidneys redistributed their blood flow after laparotomy and mobilization of the kidney. This alteration consisted of a diminution in percentage of total renal blood flow supplied to the fastest flowing component, and a diminution of renal mass supplied by that component. This effect lasted for as long as 7 days. Thereafter, the blood flow distribution remained stable.

Authors

Stanley M. Rosen, Bruno P. Truniger, Hans R. Kriek, Joseph E. Murray, John P. Merrill