Citations to this article

Basal Plasma Glucagon Levels of Man
Joseph E. Sokal, Ediz Z. Ezdinli
Joseph E. Sokal, Ediz Z. Ezdinli
Published May 1, 1967
Citation Information: J Clin Invest. 1967;46(5):778-785. https://doi.org/10.1172/JCI105578.
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Basal Plasma Glucagon Levels of Man

Abstract

The isolated perfused rat liver can serve as a bioassay system for glucagon, capable of detecting 10 mμg of this agent. Seven 15-ml plasma specimens obtained from different healthy volunteers after an overnight fast were assayed in this system; glucagon could not be detected in any of them, indicating concentrations significantly below 0.67 mμg per ml in all subjects. The effects of administering small doses of glucagon to patients were consistent with these results; imposition of increments to plasma glucagon concentration below 1 mμg per ml induced distinct and sustained increases in blood glucose.

Authors

Joseph E. Sokal, Ediz Z. Ezdinli

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Total citations by year

Year: 1981 1979 1978 1975 1974 1971 1970 1969 1968 1967 Total
Citations: 1 1 1 1 1 3 5 4 6 1 24
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Citations to this article (24)

Title and authors Publication Year
A Technique for the Isolation of Chicken Hepatocytes and Their Use in a Study of Gluconeogenesis
P Schultz, S Mistry 		Poultry science 1981
Glucagon and diabetes: A reappraisal
PJ Lefebvre, AS Luyckx 		Diabetologia 1979
The Diabetic Pancreas
GF Cahill 		New England Journal of Medicine 1978
Evidence for a physiologic role of pancreatic glucagon in human glucose homeostasis: Studies with somatostatin
JE Gerich, M Lorenzi, S Hane, G Gustafson, R Guillemin, PH Forsham 		Metabolism 1975
The Biology of Alcoholism
B Kissin, H Begleiter 		1974
Secretion of glucagon from the isolated, perfused canine pancreas
J Iversen 		Journal of Clinical Investigation 1971
Radioimmunological determination of pancreatic and gut glucagon in plasma
LG Heding 		Diabetologia 1971
Studies on the Role of Adenosine 3',5'-Monophosphate in the Hepatic Actions of Glucagon and Catecholamines
JH Exton, GA Robison, EW Sutherland, CR Park 		The Journal of biological chemistry 1971
Glucagon levels and metabolic effects in fasting man
EB Marliss, TT Aoki, RH Unger, JS Soeldner, GF Cahill 		Journal of Clinical Investigation 1970
Proceedings of the 1969 Laurentian Hormone Conference
K Sterling 		Proceedings of the 1969 Laurentian Hormone Conference 1970
Glucagon: Physiologic and Diabetogenic Role
P Felig 		New England Journal of Medicine 1970
Assay of Protein and Polypeptide Hormones
P Franchimont 		Assay of Protein and Polypeptide Hormones 1970
Effects of cortisone and glucagon on rat gestation
JE Tyson, RA Kinch, JA Stevenson 		American Journal of Obstetrics and Gynecology 1970
Effects of secretin, pancreozymin, or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man
J Dupre, JD Curtis, RH Unger, RW Waddell, JC Beck 		Journal of Clinical Investigation 1969
Effect of insulin on glucagon enhanced lipolysis in vitro
PJ Lefebvre, AS Luyckx 		Diabetologia 1969
Control of Gluconeogenesis in Liver
JH Exton, JG Corbin, CR Park 		The Journal of biological chemistry 1969
Control of Gluconeogenesis from Amino Acids in the Perfused Rat Liver
LE Mallette, JH Exton, CR Park 		The Journal of biological chemistry 1969
Hypotheses actuelles concernant le role physiologique du glucagon
P Lefebvre 		Acta Diabetologica Latina 1968
A double antibody assay for glucagon
K Shima, PP Foà 		Clinica Chimica Acta 1968
Hormonal genesis of glucose intolerance following hypoglycemia
DH Mintz, JL Finster, AL Taylor, A Fefer 		The American Journal of Medicine 1968
Metabolism of a tracer dose of palmitate-l-C14 by liver of normal and diabetic rats perfused with and without the addition of insulin
DE Haft 		Metabolism 1968
Pharmacology of Hormonal Polypeptides and Proteins
N Back, L Martini, R Paoletti 		1968
Hypotheses actuelles concernant le role physiologique du glucagon
P Lefebvre 		Acta Diabetologica 1968
INTESTINAL HORMONES AND PLASMA-INSULIN
RJ Jarrett, NM Cohen 		The Lancet 1967

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