Citations to this article

Serum-Red Cell Interactions at Low Ionic Strength: Erythrocyte Complement Coating and Hemolysis of Paroxysmal Nocturnal Hemoglobinuria Cells
David E. Jenkins Jr., … , Robert C. Hartmann, Albert L. Kerns
David E. Jenkins Jr., … , Robert C. Hartmann, Albert L. Kerns
Published May 1, 1967
Citation Information: J Clin Invest. 1967;46(5):753-761. https://doi.org/10.1172/JCI105576.
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Research Article

Serum-Red Cell Interactions at Low Ionic Strength: Erythrocyte Complement Coating and Hemolysis of Paroxysmal Nocturnal Hemoglobinuria Cells

Abstract

Complement coating and hemolysis were observed when erythrocytes from patients with paroxysmal nocturnal hemoglobinuria (PNH) were incubated in isotonic sucrose solution in the presence of small amounts of serum. Normal cells were likewise coated with complement components but did not hemolyze. Both normal and PNH erythrocytes reduced the hemolytic complement activity of the serum used in this reaction.

Authors

David E. Jenkins Jr., Robert C. Hartmann, Albert L. Kerns

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Citation information

Citations to this article in year 1973 (2)

Title and authors Publication Year
Study of Two in Vitro Diagnostic Tests for Paroxysmal Nocturnal Haemoglobinuria
G Sirchia, E Marubini, F Mercuriali, S Ferrone 		British Journal of Haematology 1973
Contemporary Topics in Molecular Immunology
RA Reisfeld, WJ Mandy 		1973

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