Title and authors | Publication | Year |
---|---|---|
Targeting Systems to the Brain Obtained by Merging Prodrugs, Nanoparticles, and Nasal Administration
G Botti, A Dalpiaz, B Pavan |
Pharmaceutics | 2021 |
Nose-to-Brain Delivery of Antiviral Drugs: A Way to Overcome Their Active Efflux?
A Dalpiaz, B Pavan |
Pharmaceutics | 2018 |
Characterization of Simian Immunodeficiency Virus (SIV) That Induces SIV Encephalitis in Rhesus Macaques with High Frequency: Role of TRIM5 and Major Histocompatibility Complex Genotypes and Early Entry to the Brain
K Matsuda, Q Dang, CR Brown, BF Keele, F Wu, I Ourmanov, R Goeken, S Whitted, NE Riddick, A Buckler-White, VM Hirsch |
Journal of virology | 2014 |
Brain Uptake of a Zidovudine Prodrug after Nasal Administration of Solid Lipid Microparticles
A Dalpiaz, L Ferraro, D Perrone, E Leo, V Iannuccelli, B Pavan, G Paganetto, S Beggiato, S Scalia |
Molecular Pharmaceutics | 2014 |
Generation of lineage-related, mucosally transmissible subtype C R5 simian-human immunodeficiency viruses capable of AIDS development, induction of neurological disease, and coreceptor switching in rhesus macaques
W Ren, A Mumbauer, A Gettie, MS Seaman, K Russell-Lodrigue, J Blanchard, S Westmoreland, C Cheng-Mayer |
Journal of virology | 2013 |
Neuropathology of wild-type and nef-attenuated T cell tropic simian immunodeficiency virus (SIVmac32H) and macrophage tropic neurovirulent SIVmac17E-Fr in cynomolgus macaques
S Clarke, N Berry, C Ham, J Alden, N Almond, D Ferguson |
Journal of Neurovirology | 2012 |
Zidovudine and Ursodeoxycholic Acid Conjugation: Design of a New Prodrug Potentially Able To Bypass the Active Efflux Transport Systems of the Central Nervous System
A Dalpiaz, G Paganetto, B Pavan, M Fogagnolo, A Medici, S Beggiato, D Perrone |
Molecular Pharmaceutics | 2012 |
Mechanisms of AIDS-related lymphoma pathogenesis
LC Huysentruyt, MS McGrath |
Future Virology | 2012 |
Current understanding of HIV-associated neurocognitive disorders pathogenesis
P Gannon, MZ Khan, DL Kolson |
Current Opinion in Neurology | 2011 |
HIV-1-infected and immune-activated macrophages induce astrocytic differentiation of human cortical neural progenitor cells via the STAT3 pathway
H Peng, L Sun, B Jia, X Lan, B Zhu, Y Wu, J Zheng |
PloS one | 2011 |
HIV-1 Clade B and C Isolates Exhibit Differential Replication: Relevance to Macrophage-Mediated Neurotoxicity
AA Constantino, Y Huang, H Zhang, C Wood, JC Zheng |
Neurotoxicity Research | 2011 |
HIV-1-Infected and Immune-Activated Macrophages Induce Astrocytic Differentiation of Human Cortical Neural Progenitor Cells via the STAT3 Pathway
H Peng, L Sun, B Jia, X Lan, B Zhu, Y Wu, J Zheng, P Proost |
PloS one | 2011 |
The endocannabinoid system in gp120-mediated insults and HIV-associated dementia
M Bari, C Rapino, P Mozetic, M Maccarrone |
Experimental Neurology | 2010 |
The role of macrophages in the development and progression of AIDS-related non-Hodgkin lymphoma
LC Huysentruyt, MS McGrath |
Journal of leukocyte biology | 2009 |
PDGF-mediated protection of SH-SY5Y cells against Tat toxin involves regulation of extracellular glutamate and intracellular calcium
X Zhu, H Yao, F Peng, S Callen, S Buch |
Toxicology and Applied Pharmacology | 2009 |
Ceramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death
A Jana, EL Hogan, K Pahan |
Journal of the Neurological Sciences | 2009 |
Parallel evolutions of the growth rate of newly diagnosed HIV cases and the proportion of potentially infective patients in Cayenne French Guiana: Should HAART be used to curb the epidemic?
M Nacher, V Vantilcke, F Huber, ME Guedj, T Vaz, C Magnien, F Djossou, A Mahamat, F Dabis, P Couppié |
Public Health | 2009 |
Mechanisms of platelet-derived growth factor-mediated neuroprotection--implications in HIV dementia
F Peng, NK Dhillon, H Yao, X Zhu, R Williams, S Buch |
The European journal of neuroscience | 2008 |
HIV-1-infected and/or immune-activated macrophage-secreted TNF-alpha affects human fetal cortical neural progenitor cell proliferation and differentiation
H Peng, N Whitney, Y Wu, C Tian, H Dou, Y Zhou, J Zheng |
Glia | 2008 |
CD163, a marker of perivascular macrophages, is up-regulated by microglia in simian immunodeficiency virus encephalitis after haptoglobin-hemoglobin complex stimulation and is suggestive of breakdown of the blood-brain barrier
JT Borda, X Alvarez, M Mohan, A Hasegawa, A Bernardino, S Jean, P Aye, AA Lackner |
The American Journal of Pathology | 2008 |
Expression of monocyte markers in HIV-1 infected individuals with or without HIV associated dementia and normal controls in Bangkok Thailand
S Ratto-Kim, T Chuenchitra, L Pulliam, R Paris, S Sukwit, S Gongwon, P Sithinamsuwan, S Nidhinandana, S Thitivichianlert, BT Shiramizu, MS de Souza, ST Chitpatima, B Sun, H Rempel, S Nitayaphan, K Williams, JH Kim, CM Shikuma, VG Valcour |
Journal of Neuroimmunology | 2008 |
Detection of amyloid beta aggregates in the brain of BALB/c mice after Chlamydia pneumoniae infection
E Boelen, FR Stassen, AJ van der Ven, MA Lemmens, HP Steinbusch, CA Bruggeman, C Schmitz, HW Steinbusch |
Acta Neuropathologica | 2007 |
Inflammatory responses following Chlamydia pneumoniae infection of glial cells
E Boelen, HW Steinbusch, I Pronk, G Grauls, P Rennert, V Bailly, CA Bruggeman, FR Stassen |
European Journal of Neuroscience | 2007 |
Limited role of COX-2 in HIV Tat-induced alterations of tight junction protein expression and disruption of the blood–brain barrier
H Pu, K Hayashi, IE Andras, SY Eum, B Hennig, M Toborek |
Brain Research | 2007 |
Chlamydia pneumoniae infection of brain cells: An in vitro study
E Boelen, HW Steinbusch, AJ van der Ven, G Grauls, CA Bruggeman, FR Stassen |
Neurobiology of Aging | 2007 |
HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1β
H Peng, N Erdmann, N Whitney, H Dou, S Gorantla, HE Gendelman, A Ghorpade, J Zheng |
Glia | 2006 |
Glycogen Synthase Kinase 3 Beta (GSK-3β) as a Therapeutic Target in NeuroAIDS
S Dewhurst, SB Maggirwar, G Schifitto, HE Gendelman, HA Gelbard |
Journal of Neuroimmune Pharmacology | 2006 |
Sulfated polymannuroguluronate, a novel anti-acquired immune deficiency syndrome drug candidate, blocks neuroinflammatory signalling by targeting the transactivator of transcription (Tat) protein
B Hui, W Xia, J Li, L Wang, J Ai, M Geng |
Journal of Neurochemistry | 2006 |
Sphingolipids in apoptosis, survival and regeneration in the nervous system
EI de Chaves |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 2006 |
A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis
C Benito, WK Kim, WK Kim, I Chavarría, CJ Hillard, K Mackie, RM Tolón, K Williams, K Williams, J Romero |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2005 |
Medizinische Therapie 2005|2006
J Schölmerich, S Burdach, H Drexler, M Hallek, W Hiddemann, WH Hörl, H Klein, M Landthaler, K Lenz, K Mann, J Mössner, U Müller-Ladner, J Reichen, W Schmiegel, JO Schröder, W Seeger, W Stremmel, N Suttorp, LS Weilemann, JC Wöhrle |
2005 | |
Multiorganinfektionen — komplexe klinisch-infektiologische Krankheiten
Bergmann F, Bienzle U, Breithaupt H, Grimminger F, Lohmeyer J, Schürmann D, Seeger W, Suttorp N, Walmrath HD |
2005 | |
Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase
A Jana, K Pahan |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2004 |
Effects of apolipoprotein E on the human immunodeficiency virus protein tat in neuronal cultures and synaptosomes
CB Pocernich, R Sultana, E Hone, J Turchan, RN Martins, V Calabrese, A Nath, DA Butterfield |
Journal of Neuroscience Research | 2004 |
Stromal cell-derived factor 1-mediated CXCR4 signaling in rat and human cortical neural progenitor cells
H Peng, Y Huang, J Rose, D Erichsen, S Herek, N Fujii, H Tamamura, J Zheng |
Journal of Neuroscience Research | 2004 |
RON Receptor Tyrosine Kinase, a Negative Regulator of Inflammation, Inhibits HIV-1 Transcription in Monocytes/Macrophages and Is Decreased in Brain Tissue from Patients with AIDS
ES Lee, P Kalantari, S Tsutsui, A Klatt, J Holden, PH Correll, C Power, AJ Henderson |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
Multiple Actions of the Human Immunodeficiency Virus Type-1 Tat Protein on Microglial Cell Functions
L Minghetti, S Visentin, M Patrizio, L Franchini, MA Ajmone-Cat, G Levi |
Neurochemical Research | 2004 |
Tumor necrosis factor-alpha at the crossroads of neuronal life and death during HIV-associated dementia
RN Saha, K Pahan |
Journal of Neurochemistry | 2003 |
Encyclopedia of the Neurological Sciences
S Mookherjee |
Encyclopedia of the Neurological Sciences | 2003 |
Choroid plexus controls brain availability of anti-HIV nucleoside analogs via pharmacologically inhibitable organic anion transporters
N Strazielle, MF Belin, JF Ghersi-Egea |
AIDS | 2003 |
Tumor necrosis factor-α at the crossroads of neuronal life and death during HIV-associated dementia
RN Saha, K Pahan |
Journal of Neurochemistry | 2003 |
Expression of chemokines and their receptors in human and simian astrocytes: Evidence for a central role of TNF? and IFN? in CXCR4 and CCR5 modulation
J Croitoru-Lamoury, GJ Guillemin, FD Boussin, B Mognetti, LI Gigout, A Ch�ret, B Vaslin, RL Grand, BJ Brew, D Dormont |
Glia | 2003 |
AIDS and Other Manifestations of HIV Infection
D Ashkin, Y Hale, E Hollender, M Lauzardo, M Narita, AE Pitchenik, M Salfinger, JJ Stambaugh |
AIDS and Other Manifestations of HIV Infection | 2003 |
CENTRALNERVOUSSYSTEMDAMAGE, MONOCYTES ANDMACROPHAGES, ANDNEUROLOGICALDISORDERS INAIDS
KC Williams, WF Hickey |
Annual Review of Neuroscience | 2002 |
Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia
X Liu, M Jana, S Dasgupta, S Koka, J He, C Wood, K Pahan |
The Journal of biological chemistry | 2002 |
Progress toward a human CD4/CCR5 transgenic rat model for de novo infection by human immunodeficiency virus type 1
OT Keppler, FJ Welte, TA Ngo, PS Chin, KS Patton, CL Tsou, NW Abbey, ME Sharkey, RM Grant, Y You, JD Scarborough, W Ellmeier, DR Littman, M Stevenson, IF Charo, BG Herndier, RF Speck, MA Goldsmith |
Journal of Experimental Medicine | 2002 |
Susceptibility of rat-derived cells to replication by human immunodeficiency virus type 1
OT Keppler, W Yonemoto, FJ Welte, KS Patton, D Iacovides, RE Atchison, T Ngo, DL Hirschberg, RF Speck, MA Goldsmith |
Journal of virology | 2001 |
Human immunodeficiency virus type-1 Tat protein induces nuclear factor (NF)-κB activation and oxidative stress in microglial cultures by independent mechanisms
A Nicolini, MA Ajmone-Cat, A Bernardo, G Levi, L Minghetti |
Journal of Neurochemistry | 2001 |
Brain and CSF entry of the novel nonnucleoside reverse transcriptase inhibitor, GW420867X
S Thomas, L Cass, W Prince, M Segal |
NeuroReport | 2000 |
Advances in Molecular and Cell Biology
KJ Clemetson |
Advances in Molecular and Cell Biology | 1997 |