JCI - Citations to EVIDENCE THAT INSULIN RELEASE IS THE MECHANISM FOR EXPERIMENTALLY INDUCED LEUCINE HYPOGLYCEMIA IN MAN

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EVIDENCE THAT INSULIN RELEASE IS THE MECHANISM FOR EXPERIMENTALLY INDUCED LEUCINE HYPOGLYCEMIA IN MAN

John C. Floyd Jr., … , Ralph F. Knope, Jerome W. Conn

John C. Floyd Jr., … , Ralph F. Knope, Jerome W. Conn

Published November 1, 1963
Citation Information: J Clin Invest. 1963;42(11):1714-1719. https://doi.org/10.1172/JCI104857.

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Citations to this article (77)

Title and authors	Publication	Year
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Clinical and socio-demographic parameters contributing to treatment incompliance in Palestinian patients with diabetes B Salameh, H Salem, JM Abdallah, A Batran, EO Naerat	Therapeutic Advances in Endocrinology and Metabolism	2019
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Clinical Nutrition and Aging: Sarcopenia and Muscle Metabolism R Manders, J Little, S Forbes, D Candow	Clinical Nutrition and Aging: Sarcopenia and Muscle Metabolism	2016
Bodybuilding supplementation and tooth decay MS Ali, H Batley, F Ahmed	BDJ	2015
Glucose Intake and Utilization in Pre-Diabetes and Diabetes G D’Antona		2015
Mitochondrial GTP Insensitivity Contributes to Hypoglycemia in Hyperinsulinemia Hyperammonemia by Inhibiting Glucagon Release RG Kibbey, CS Choi, HY Lee, O Cabrera, RL Pongratz, X Zhao, AL Birkenfeld, C Li, PO Berggren, C Stanley, GI Shulman		2014
Is carbohydrate needed to further stimulate muscle protein synthesis/hypertrophy following resistance exercise? VC Figueiredo, D Cameron-Smith	Journal of the International Society of Sports Nutrition	2013
Obesity and diabetes related plasma amino acid alterations Y Zhou, L Qiu, Q Xiao, Y Wang, X Meng, R Xu, S Wang, R Na	Clinical Biochemistry	2013
Impact of diet composition on blood glucose regulation WR Russell, A Baka, I Björck, N Delzenne, D Gao, HR Griffiths, E Hadjilucas, K Juvonen, S Lahtinen, M Lansink, L Loon, H Mykkänen, E Östman, G Riccardi, S Vinoy, MO Weickert	Critical Reviews in Food Science and Nutrition	2013
Orally Administered Whey Proteins Have Comparable Effect on C-Peptide Secretion in Healthy Subjects as Standard C-Peptide Stimulation Tests E Wildová, P Dlouhý, P Kraml, J Rambousková, V Šmejkalová, J Potočková, M Anděl	Physiological research / Academia Scientiarum Bohemoslovaca	2013
Insulinotropic and Muscle Protein Synthetic Effects of Branched-Chain Amino Acids: Potential Therapy for Type 2 Diabetes and Sarcopenia R Manders, J Little, S Forbes, D Candow	Nutrients	2012
Altered Metabolic Signature in Pre-Diabetic NOD Mice R Madsen, VS Banday, T Moritz, J Trygg, K Lejon, K Maedler	PloS one	2012
Metabolic Regulation in Progression to Autoimmune Diabetes M Sysi-Aho, A Ermolov, PV Gopalacharyulu, A Tripathi, T Seppänen-Laakso, J Maukonen, I Mattila, ST Ruohonen, L Vähätalo, L Yetukuri, T Härkönen, E Lindfors, J Nikkilä, J Ilonen, O Simell, M Saarela, M Knip, S Kaski, E Savontaus, M Orešič	PLoS computational biology	2011
Oxidative Stress and Disease I Paur, M Carlsen, B Halvorsen, R Blomhoff	Herbal Medicine	2011
Advances in Immunology E Pinaud, M Marquet, R Fiancette, S Péron, C Vincent-Fabert, Y Denizot, M Cogné	Advances in Immunology Volume 110	2011
Post-exercise ingestion of different amounts of protein affects plasma insulin concentration in humans M Morifuji, T Aoyama, A Nakata, C Sambongi, J Koga, K Kurihara, M Kanegae, K Suzuki, M Higuchi	European Journal of Sport Science	2011
Vitamins & Hormones KJ Hare, FK Knop	Vitamins & Hormones	2010
Comparison of Different Sources and Degrees of Hydrolysis of Dietary Protein: Effect on Plasma Amino Acids, Dipeptides, and Insulin Responses in Human Subjects M Morifuji, M Ishizaka, S Baba, K Fukuda, H Matsumoto, J Koga, M Kanegae, M Higuchi	Journal of Agricultural and Food Chemistry	2010
Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity KH Pietiläinen, J Naukkarinen, A Rissanen, J Saharinen, P Ellonen, H Keränen, A Suomalainen, A Götz, T Suortti, H Yki-Järvinen, M Oresic, J Kaprio, L Peltonen	PLoS Medicine	2008
Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes M Oresic, S Simell, M Sysi-Aho, K Näntö-Salonen, T Seppänen-Laakso, V Parikka, M Katajamaa, A Hekkala, I Mattila, P Keskinen, L Yetukuri, A Reinikainen, J Lähde, T Suortti, J Hakalax, T Simell, H Hyöty, R Veijola, J Ilonen, R Lahesmaa, M Knip, O Simell	Journal of Experimental Medicine	2008
Idiopathic Hypoglycaemia and Children of Low Birth-Weight M Cox, HG Dunn	Developmental Medicine & Child Neurology	2008
Nutritional Interventions to Promote Post-Exercise Muscle Protein Synthesis: R Koopman, WH Saris, AJ Wagenmakers, LJ van Loon	Sports Medicine	2007
Dietary amino acids fed in free form and as protein components do not differently affect postprandial plasma insulin, glucagon, growth hormone and corticosterone responses in rats JA Nolles, EM van Straten, BI Bremer, RE Koopmanschap, MW Verstegen, VV Schreurs	Journal of Animal Physiology and Animal Nutrition	2006
Control of blood glucose in type 2 diabetes without weight loss by modification of diet composition MC Gannon, FQ Nuttall	Nutrition & Metabolism	2006
Co-Ingestion of a Protein Hydrolysate with or without Additional Leucine Effectively Reduces Postprandial Blood Glucose Excursions in Type 2 Diabetic Men RJ Manders, R Koopman, WE Sluijsmans, R van den Berg, K Verbeek, WH Saris, AJ Wagenmakers, LJ van Loon	The Journal of nutrition	2006
Relationship of causative genetic mutations in maple syrup urine disease with their clinical expression MM Nellis, A Kasinski, M Carlson, R Allen, AM Schaefer, EM Schwartz, DJ Danner	Molecular Genetics and Metabolism	2003
Ingestion of Protein Hydrolysate and Amino Acid–Carbohydrate Mixtures Increases Postexercise Plasma Insulin Responses in Men LJ van Loon, M Kruijshoop, H Verhagen, WH Saris, AJ Wagenmakers	The Journal of nutrition	2000
Plasma insulin responses after ingestion of different amino acid or protein mixtures with carbohydrate LJ van Loon, WH Saris, H Verhagen, AJ Wagenmakers	The American journal of clinical nutrition	2000
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Potentiation by previous nutrients of glibenclamide-induced insulin release in man. An effect which is counteracted by meal-induced retardation of drug absorption V Grill, S Efendic, G Regitz	Scandinavian Journal of Clinical & Laboratory Investigation	1986
Increased dietary leucine changes the rhythm of prolactin secretion N Miller, PA Smith, AM Walker	Metabolism	1986
Calcium and Cell Function B Hellman, E Gylfe	Calcium and Cell Function	1986
Diagnosis and Management of Endocrine-related Tumors RJ Santen, A Manni		1984
Neutral amino acid transport in isolated rat pancreatic islets M Prentki, AE Renold	The Journal of biological chemistry	1983
A single mechanism for the stimulation of insulin release and 86Rb+ efflux from rat islets by cationic amino acids S Charles, T Tamagawa, JC Henquin	Biochemical Journal	1982
Leucine meal increases glutamine and total nitrogen release from forearm muscle TT Aoki, MF Brennan, GF Fitzpatrick, DC Knight	Journal of Clinical Investigation	1981
Effects of alloxan on the islets of Langerhans inhibition of leucine metabolism and insulin secretion LA Borg	Biochimica et Biophysica Acta (BBA) - General Subjects	1981
Effects of amino acids on membrane potential and 86Rb+ fluxes in pancreatic beta-cells JC Henquin, HP Meissner	American journal of physiology. Endocrinology and metabolism	1981
Hypoglycemia in Children Boris, JI Wolfsdorf	Pediatric Clinics of North America	1979
Amino Acid Levels in Plasma and Muscle of Rats after Intravenous Administration of Different Amino Acid Infusions T Kishi, Y Iwasawa, H Itoh, I Chibata	JPEN. Journal of parenteral and enteral nutrition	1979
Nutrition and Metabolism of the Fetus and Infant HK Visser		1979
Effect of Starvation on the Turnover and Metabolic Response to Leucine RS Sherwin	Journal of Clinical Investigation	1978
Beta cell nesidioblastosis K Becker, U Wendel, H Przyrembel, M Tsotsalas, H Mntefering, HJ Bremer	European Journal of Pediatrics	1978
Diabetes mellitus · A E Cerasi, P Dieterle, H Ege, A Englhardt, H Frerichs, W Gepts, A Hasselblatt, HR Henrichs, L Herberg, JJ Hoet, H Hungerland, K Jahnke, RJ Jarrett, G Jörgensen, KH Jørgensen, H Kasemir, H Keen, L Kerp, V Leclercq-Meyer, H Liebermeister, G Löffler, R Luft, WJ Malaisse, J Markussen, M Möllering, H Schadewaldt, J Schlichtkrull, K Schöffling, U Schwedes, PC Scriba, F Sundby, KH Usadel, L Weiss, H Zimmermann, K Oberdisse		1975
Characterization of cyclic 3', 5'-nucleotide phosphodiesterase activity in an islet cell tumor of the syrian hamster UK Schubart, L Udem, SG Baum, OM Rosen	Molecular and Cellular Endocrinology	1974
Leucine and its derivatives as potential elicitors of insulin secretion in rats VD Warner, AM Warner, JR Vasselli, E Decke, FX Pi-Sunyer, SC Woods	Journal of Pharmaceutical Sciences	1973
The role of carbohydrate and oral agents in the treatment of diabetes mellitus WD Odell	California medicine	1973
AMINO ACIDS AND INSULIN WP Jackson	Transactions of the Royal Society of South Africa	1972
Newer Methods of Nutritional Biochemistry GA Christie	Newer Methods of Nutritional Biochemistry	1972
Hypersecretion of insulin after the administration of l-leucine to obese children L Loridan, A Sadeghi-Nejad, Boris	The Journal of Pediatrics	1971
Pathophysiologie und Klinik / Pathophysiology and Clinical Considerations EF Pfeiffer		1971
A possible role for the exocrine pancreas in the pathogenesis of neonatal leucine-sensitive hypoglycemia RE Brown, RB Young	The American Journal of Digestive Diseases	1970
The Structure and Metabolism of the Pancreatic Islets A Lambert, L Orci, Y Kanazawa, A Renold, C Rouiller	The Structure and Metabolism of the Pancreatic Islets	1970
Organ culture of fetal rat pancreas II. Insulin release induced by amino and organic acids, by hormonal peptides, by cationic alterations of the medium and by other agents AE Lambert, B Jeanrenaud, A Junod, AE Renold	Biochimica et Biophysica Acta (BBA) - General Subjects	1969
Fat cell function and insulin in a patient with generalized lipodystrophy Boris, L Loridan	The Journal of Pediatrics	1969
Schering Symposium on Endocrinology, Berlin, May 26 to 27, 1967 SS Fajans, JC Floyd, RF Knopf, JW Conn	Schering Symposium on Endocrinology, Berlin, May 26 to 27, 1967	1969
FURTHER STUDIES ON DIAZOXIDE SUPPRESSION OF INSULIN RELEASE FROM ABNORMAL AND NORMAL ISLET TISSUE IN MAN SS Fajans, JC Floyd, CA Thiffault, RF Knopf, TS Harrison, JW Conn	Annals of the New York Academy of Sciences	1968
Immunoassay of insulin and glucagon KW Taylor, SL Howell, W Montague, JC Edwards	Clinica Chimica Acta	1968
Oral Hypoglycemic Agents and the Mechanism of Diabetes Mellitus DS Feingold, EE Parris, FF Davidoff	New England Journal of Medicine	1968
Serum-insulin changes following administration of L-leucine to children DB Grant	Archives of disease in childhood	1968
Proceedings of the 1966 Laurentian Hormone Conference AM Bongiovanni, WR Eberlein, AS Goldman, M New	Proceedings of the 1966 Laurentian Hormone Conference	1967
The influence of chlorpropamide pre-treatment on insulin and growth hormone release after arginine L Riggs, D Rabinowitz, TJ Merimee	Postgraduate medical journal	1967
Benzothiadiazine suppression of insulin release from normal and abnormal islet tissue in man SS Fajans, JC Floyd, RF Knopf, J Rull, EM Guntsche, JW Conn	Journal of Clinical Investigation	1966
Insulin secretion in response to protein ingestion JC Floyd, SS Fajans, JW Conn, RF Knopf, J Rull	Journal of Clinical Investigation	1966
Stimulation of insulin secretion by amino acids JC Floyd, SS Fajans, JW Conn, RF Knopf, J Rull	Journal of Clinical Investigation	1966
Comportement des acides amin�s plasmatiques libres chez des chiens normaux et des chiens pancr�atectomis�s apr�s administration intraveineuse rapide de l-leucine A Czyzyk, W Schittek	Acta Diabetologica Latina	1966
Insulin levels in monkey plasma determined by immunoassay FE Wherry, RE Miller, JW Mason	Metabolism	1966
Effect of L-leucine on glucose turnover in dogs SS Sanbar	Metabolism	1966
Leucine-sensitive hypoglycemia Z Javier, H Gershberg	The American Journal of Medicine	1966
Erzeugung von Krankheitszuständen durch das Experiment E Eichenberger, PP Foà, TA Grillo, O Eichler		1966
�ber den insulinabbau in der isolierten Rattenleber bei Perfusion mit Rattenserum und Leucin K Kopetz, H Brgi, ER Froesch, K Schwarz	Diabetologia	1966
A Comparison of Leucine- and Acetoacetate-induced Hypoglycemia in Man^* SS Fajans, JC FLOYD, RF Knopf, JW Conn	Journal of Clinical Investigation	1964
Leucine-Induced Hypoglycemia HM Haddad, WC Roberts, P Pronove, FC Bartter	New England Journal of Medicine	1962

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