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INTRAVENOUS TRYPSIN: ITS ANTICOAGULANT, FIBRINOLYTIC AND THROMBOLYTIC EFFECTS
Irving Innerfield, … , Alfred Schwarz, Alfred Angrist
Irving Innerfield, … , Alfred Schwarz, Alfred Angrist
Published December 1, 1952
Citation Information: J Clin Invest. 1952;31(12):1049-1055. https://doi.org/10.1172/JCI102698.
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Research Article

INTRAVENOUS TRYPSIN: ITS ANTICOAGULANT, FIBRINOLYTIC AND THROMBOLYTIC EFFECTS

Abstract

Authors

Irving Innerfield, Alfred Schwarz, Alfred Angrist

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Citations to this article (51)

Title and authors Publication Year
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Novel endoscopic papillectomy for reducing postoperative adverse events (with videos)
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Fibrinolytic enzymes in ascites during experimental acute pancreatitis in rats
Y Etoh, H Sumi, H Tsushima, M Maruyama, H Mihara 		International Journal of Gastrointestinal Cancer 1992
The development of thrombolytic therapy
S Sherry 		Journal of the American College of Cardiology 1987
Clarence Agress pioneers experimental thrombolysis of the coronary artery in 1952
E Shapiro 		Journal of the American College of Cardiology 1987
Pharmacology of fibrinolytic agents
GH Barlow 		Progress in Cardiovascular Diseases 1979
Acquired Thrombophilia: A Hitherto Unrecognized Procoagulant-Antithrombin Imbalance
I Innerfield 		Scandinavian Journal of Haematology 1976
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ENHANCEMENT OF FIBRINOLYTIC ACTIVITY
I Innerfield 		Lancet 1974
Thrombosis and Bleeding Disorders
EF Mammen 		Thrombosis and Bleeding Disorders 1971
Experimentelle Thrombenerzeugung Vergleichende Untersuchungen
M Gröber 		European Surgery 1969
An experimental model for the study of thrombosis
J Pflug, J Calnan, EG Olsen 		British Journal of Surgery 1968
QUANTITATIVE ASPECTS OF ORAL ENZYME THERAPY*
I Innerfield 		Transactions of the New York Academy of Sciences 1966
Bradykininogen and bradykinin in the cardiovascular shock produced by proteolytic enzymes
AP Corrado, ML Reis, IF Carvalho, CR Diniz 		Biochemical Pharmacology 1966
Experimental in vitro studies on the lysis of blood-clot
GH Dunstone, LB Fleming, IA Porter, DN Walder 		British Journal of Surgery 1964
Allergy to trypsin
LH Criep, LR Beam 		Journal of allergy 1964
Lysis of a Cerebral Thrombus with Fibrinolysin: A Case Report
FP McBroom 		Journal of the National Medical Association 1963
EXPERIMENTAL FIBRINOLYSIS
P FANTL 		1963
IX. the Comparative Activity in Vivo of Trypsin and Aspergillin O (Mold Fibrinolysin)
M Stefanini, HM Marin, F Soardi, A Mossa 		Angiology 1962
Proteolysis, Fibrinolysis, and Coagulation: Significance in Thrombolytic Therapy
B Alexander, L Pechet, A Kliman 		Circulation 1962
Ergebnisse der Inneren Medizin und Kinderheilkunde
L Heilmeyer, R Schoen, B Rudder 		1960
Angeborene Herz- und Gefässmissbildungen Durchblutungsstörungen des Herzmuskels
W Doerr, J Eberl, F Grosse-Brockhoff, F Loogen, A Schaede, G Schimert, W Schimmler, H Schwalb 		1960
Krankheiten der Gefässe
E Wollheim, J Zissler 		1960
Physiology of pancreatic secretion
DA Dreiling 		The American Journal of Digestive Diseases 1959
Visualization of the Pancreas by Aortography
WS McCune, WW Stanbro 		Annals of Surgery 1959
A Preliminary Report on the Radiologic Evaluation of Trypsin in Certain Chronic Chest Diseases
NE Silbert 		Chest 1959
Effects of Intravenous Administration of Fibrinolysin (Plasmin) in Man
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The Use of Trypsin in the Therapy of Tuberculous Lymphadenitis and Tuberculous Fistulae* *This report is based on work done in Malben's Tuberculosis Hospital in Israel, which is supported by the American Joint Distribution Committee which receives its funds through the United Jewish Appeal
C Rapoport 		Chest 1958
Use of Trypsin in the Treatment of Experimental Coronary Thrombosis
CR Conrad, AF Geis 		Circulation research 1958
Intravenous Protein-Free Pyrogen: A Powerful Fibrinolytic Agent in Man
KN Kaulla 		Circulation 1958
BIOCHEMICAL, EXPERIMENTAL, AND CLINICAL STUDIES OF PROTEOLYTIC ENZYMES: WITH PARTICULAR REFERENCE TO THE FIBRINOLYTIC ENZYME OF HUMAN PLASMA
S Sherry, N Alkjaersig 		Annals of the New York Academy of Sciences 1957
Intramuscular Injection of Trypsin: Its Value as a Thrombolytic and Anti-Inflammatory Agent
KM Moser 		New England Journal of Medicine 1957
Trypsin Intramuscularly in 129 Cases of Thrombophlebitis1
MM Fisher, ND Wilensky 		Angiology 1957
Exocrine pancreatic secretion
DA Dreiling, HD Janowitz 		The American Journal of Medicine 1956
Use of Enzymes in Surgery
EL Howes 		Surgical Clinics of North America 1956
Fünfter Kongress der Europäischen Gesellschaft für Hämatologie, Freiburg i. Br., 20. bis 24. September 1955 / Cinquième Congrès de la Société Européenne d’Hématologie, Freiburg i. Br., Allemagne, 20–24 Septembre 1955
H Begemann 		1956
Die potentielle fibrinolytische Aktivit�t bei thromboembolischen Erkrankungen
S Witte 		Klinische Wochenschrift 1956
BUCCAL AND INTRAMUSCULAR TRYPSIN IN RESPIRATORY TRACT INFECTION
I Innerfield, IS Shiner, EV Duany 		1956
Inhibition of Acyl Trypsins by Human Serum
M Bier, JS Ram, FF Nord 		Nature 1955
The intra-aortic administration of fibrinolytic enzymes in peripheral emboli experimentally induced in the aorta
E Krahl, GH Pratt, G Doehner, LM Rousselot 		The American Journal of Surgery 1955
Intramuscular Trypsin in the Treatment of Chronic Thrombophlebitis
CJ Wildman 		Angiology 1955
Fortschritte der Serologie
H Schmidt 		1955
The Use of Human Serum Albumin in the Management of Acute Pancreatitis
DW Elliott, RM Zollinger, R Moore, EH Ellison 		Gastroenterology 1955
THE FIBRINOLYTIC ACTIVITY OF STREPTOKINASE ACTIVATED HUMAN PLASMIN 1
S Sherry 		Journal of Clinical Investigation 1954
The Enzymatic Dissolution Of Experimental Arterial Thrombi in the Dog by Trypsin, Chymotrypsin and Plasminogen Activators12
S Sherry, A Titchener, L Gottesman, P Wasserman, W Troll 		Journal of Clinical Investigation 1954
Lysis of thrombi produced by sodium morrhuate in the femoral vein of dogs by human plasmin (fibrinolysin)
EE Cliffton, CE Grossi, D Cannamela 		Annals of Surgery 1954
Use of Parenteral Trypsin in Acute Inflammatory and Thrombotic Ocular Disturbances*
JM Hopen 		1954
Intravenous Trypsin
A Taylor, IR Wright 		Circulation 1954
THE KIDNEY AND METABOLIC DISEASE
MD Milne 		The Lancet 1953
An evaluation of anticoagulant therapy
IS Wright 		The American Journal of Medicine 1953
Enzymes in Clinical Medicine: Recent Developments in the Practical Application of Enzymes to Clinical Medicine
HJ Tagnon 		New England Journal of Medicine 1953

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