Review Series

Cancer biotherapy

Series edited by David Kirn

The series reviews the emerging field of tumor-targeted microbes, which offer great potential for antitumoral potency and selective targeting of cancer cells and act by mechanisms not subject to cross-resistance when combined with standard therapies.

Articles in series

Use of preferentially replicating bacteria for the treatment of cancer
Mario Sznol, … , Li-mou Zheng, Ivan King
Mario Sznol, … , Li-mou Zheng, Ivan King
Published April 15, 2000
Citation Information: J Clin Invest. 2000;105(8):1027-1030. https://doi.org/10.1172/JCI9818.
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Use of preferentially replicating bacteria for the treatment of cancer

Abstract

Authors

Mario Sznol, Stanley L. Lin, David Bermudes, Li-mou Zheng, Ivan King

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Poxvirus vectors: orphaned and underappreciated
Michael J. Mastrangelo, … , Leonard Gomella, Edmund C. Lattime
Michael J. Mastrangelo, … , Leonard Gomella, Edmund C. Lattime
Published April 15, 2000
Citation Information: J Clin Invest. 2000;105(8):1031-1034. https://doi.org/10.1172/JCI9819.
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Poxvirus vectors: orphaned and underappreciated

Abstract

Authors

Michael J. Mastrangelo, Laurence C. Eisenlohr, Leonard Gomella, Edmund C. Lattime

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Reovirus as a novel oncolytic agent
Kara L. Norman, Patrick W.K. Lee
Kara L. Norman, Patrick W.K. Lee
Published April 15, 2000
Citation Information: J Clin Invest. 2000;105(8):1035-1038. https://doi.org/10.1172/JCI9871.
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Reovirus as a novel oncolytic agent

Abstract

Authors

Kara L. Norman, Patrick W.K. Lee

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Prodrug-activating systems in suicide gene therapy
Caroline J. Springer, Ion Niculescu-Duvaz
Caroline J. Springer, Ion Niculescu-Duvaz
Published May 1, 2000
Citation Information: J Clin Invest. 2000;105(9):1161-1167. https://doi.org/10.1172/JCI10001.
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Prodrug-activating systems in suicide gene therapy

Abstract

Authors

Caroline J. Springer, Ion Niculescu-Duvaz

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Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer
Terry Hermiston
Terry Hermiston
Published May 1, 2000
Citation Information: J Clin Invest. 2000;105(9):1169-1172. https://doi.org/10.1172/JCI9973.
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Immunomodulation of cancer: potential use of selectively replicating agents
Siamak Agha-Mohammadi, Michael T. Lotze
Siamak Agha-Mohammadi, Michael T. Lotze
Published May 1, 2000
Citation Information: J Clin Invest. 2000;105(9):1173-1176. https://doi.org/10.1172/JCI10026.
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Immunomodulation of cancer: potential use of selectively replicating agents

Abstract

Authors

Siamak Agha-Mohammadi, Michael T. Lotze

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Regulatable systems: applications in gene therapy and replicating viruses
Siamak Agha-Mohammadi, Michael T. Lotze
Siamak Agha-Mohammadi, Michael T. Lotze
Published May 1, 2000
Citation Information: J Clin Invest. 2000;105(9):1177-1183. https://doi.org/10.1172/JCI10027.
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Regulatable systems: applications in gene therapy and replicating viruses

Abstract

Authors

Siamak Agha-Mohammadi, Michael T. Lotze

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Series Introduction: Replication-selective microbiological agents: fighting cancer with targeted germ warfare
David H. Kirn
David H. Kirn
Published April 1, 2000
Citation Information: J Clin Invest. 2000;105(7):837-839. https://doi.org/10.1172/JCI9761.
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Conditionally replicating herpes vectors for cancer therapy
Robert L. Martuza
Robert L. Martuza
Published April 1, 2000
Citation Information: J Clin Invest. 2000;105(7):841-846. https://doi.org/10.1172/JCI9744.
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Replication-selective adenoviruses as oncolytic agents
Carla Heise, David H. Kirn
Carla Heise, David H. Kirn
Published April 1, 2000
Citation Information: J Clin Invest. 2000;105(7):847-851. https://doi.org/10.1172/JCI9762.
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Replication-selective adenoviruses as oncolytic agents

Abstract

Authors

Carla Heise, David H. Kirn

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