Robert Lefkowitz, physician-scientist from Duke University and the 2012 Nobel laureate in chemistry for his studies of GPCRs has recently written a memoir called A Funny Thing Happened on the Way to Stockholm, and we couldn’t resist the opportunity to ask Dr. Lefkowitz to reflect more extensively on a life well lived and a career full of phenomenal insights and ample laughter. Hear his reflections on competition in academia as well as the push and pull of a life as a physician-scientist.