March 13, 2025: Revised the guaranteed reviews and rewards section by adding more details
December 15, 2024: Added Public Health to create Clinical Research and Public Health category; revised description of Research category.
December 2, 2024: Added announcement of publication fee change for January 1, 2025.
November 13, 2024: Dual-Journal Submission is live.
November 6, 2024: Added link to NIH race and ethnicity guideline resvisions.
November 1, 2024: Added Dual-Journal Submission option.
October 9, 2024: Added guidelines for articifical intelligence technologies.
December 13, 2023: Added requirement for “Sex as a biological variable” paragraph (effective January 1, 2024).
November 14, 2023: Updated publication fee for 2024.
October 24, 2023: Revised "Graphs and images" section.
October 9, 2023: Revised to require uploading of supporting data values at first submission; and publication of blot gel images if manuscript is accepted.
September 15, 2023: Reformatted "Data availability" section.
July 12, 2023: Added links to "How to prepare tables" and "How to prepare Supporting data files."
April 6, 2023: Added requirements for Data availability subsection and Supporting data values; updated guideline for repeated use of figures or panels.
January 13, 2022: Updated publication fee.
November 22, 2022: Added external review policy.
November 21, 2022: Added notice that effective January 1, 2023, the publication fee will increase from $5,200 to $5,300 (Research and Clinical Medicine).
November 1 2022: Added COI section for misconduct allegations.
April 21, 2022: Added "Submissions" section under Editorial policies and practices.
March 30, 2022: Changed email address for Video abstracts from editorial@the-jci.org to production@the-jci.org.
March 10, 2022: Updated so only current publication fee (active with January 4 issue) is shown; added language regarding requests for fee reduction.
March 1, 2022: Changed from Johns Hopkins to Northwestern/Chicago.
January 4, 2022: Removed Concise Communication category.
December 20, 2021: Updated "Why submit" and "Copyright" information to indicate January 4, 2022, change for author copyright and CC BY license.
October 4, 2021: Added notice that with the January 4, 2022, issue of the JCI, all articles will be published under CC BY 4.0; and publication fees will increase from $4,650 to $5,200 (Research and Clinical Medicine) and $3,500 to $3,900 (Concise Communication).
September 15, 2021: Clarified text regarding reviewer suggestions and exclusion.
August 31, 2021: Added "Demographic reporting" section under Experimental design.
August 17, 2021: Revised "Author information" page to "Author information center"; added kiosk pages for first and revised submissions.
July 19, 2021: Added text to "Graphs and images" regarding Proofig.
June 21, 2021: Added Letter to the Editor category; relevant navigation areas.
March 16, 2021: Replaced content of linked Figure and Reference kiosk pages.
November 10, 2020: Revised style for references with 3 or more authors to list only the first author plus ", et al."
October 16, 2020: Under Editorial policies and practices, added statement about JCI Insight review of manuscripts declined by the JCI.
July 17, 2020: Title word limit updated to 15.
June 11, 2020: Added medRxiv to preprints.
April 28, 2020: Revised "Prior publication" to state that preprints are acceptable; removed all other items from this section.
November 14, 2019: Added bookmark for References.
April 29, 2019: Added policy requiring description of method used for assigning authorship order among co–first authors.
March 21, 2019: For preprints and bioRxiv, specified research manuscripts.
February 11, 2019: Added requirement for Word/RTF file for first submission.
February 7, 2019: Added preprints to the References section.
February 5, 2019: Added embargo information to In-Press preview section.
January 2, 2019: Added Reviewer Rewards section.
January 1, 2019: Changed publication fee from $4500 to $4650
October 2, 2018: Removed date of initiation (April 25) of policy allowing transfer from bioRxiv.
June 1, 2018: Added requirement that quantitative graphs show distribution of data.
April 25, 2018: Added option to submit by transferring from bioRxiv.
March 27, 2018: Added to Publication proofs section that substantive changes are not acceptable.
February 22: Added Graphical abstracts (online).
January 15, 2018: Added new policy: consideration of preprints.
January 1, 2018: Added In-Press Preview description.
November 1, 2017: Replaced Brief Reports with new category: Concise Communications.
July 1, 2017: Revised to replace Duke with Johns Hopkins.
June 21, 2017: Revised to omit requirement for submission PDFs that figure and corresponding legend appear on same page.
March 2, 2017: Revised Required documents/First time submissions and /Revised submissions to specify that in the PDF, legends should appear on same page as figures.
February 1, 2017: Clarified application of CC BY copyright licenses for authors of research articles whose funders require it.
January 7, 2017: Brief report publication fee changed from $2900 to $3000.
December 21, 2016: Added notice that submission fee is discontinued January 1, 2017.
October 7, 2016: Added Indexing information.
July 26, 2016: Figure instructions page revised to specify 600 ppi for all figures.
May 25 2016: Changed figure submission from acceptance to provisional acceptance; added text prohibiting reuse of data within article.
April 15, 2016: Updated link to new License information page.
April 6, 2016: Added recommendation to use EndNote for references.
January 20, 2016: Added link to Figures at top of page; in Figure Instructions, changed requirement from CMYK to RGB.
November 24, 2015: Added Executive Editor position.
October 9, 2015: Added link to JCI’s Terms of Use under After acceptance > Copyright section.
August 18, 2015: Revised "Authors and affiliations" to include instructions for group/consortium authors.
July 2, 2015: Added "Author contributions" requirement.
June 17, 2015: Changed manuscript designation "Regular" to "Research."
May 18, 2015: Figure legend word limit changed from 250 to 300.
May 6, 2015: Revised description of Clinical Medicine category.
March 17, 2015: Added description of guaranteed review for ASCI members.
December 4, 2014: Added word limit and flat publication fee to begin with April 2015 issue.
November 7, 2014: Combined the following pages: Research categories, Submitting your work to the JCI, Clinical medicine submission guidelines, Editorial policies and practices, and Conflict of interest policies. Added Intellectual property text to Conflict of interest policy.
March 25, 2014: Added requirement to deposit ChIP-Seq and RNA-Seq data.
December 3, 2012: Added Clinical Medicine category.
August 23, 2012: Added clarification that full uncut gels/blots be highlighted to demonstrate which lanes apply to the submitted manuscript.
August 6, 2012: Posting of "Gene nomenclature and style" document.
April 8, 2012: Upload of full uncut gels/blots for first-time submissions no longer required.
December 15, 2024: Added Public Health to create Clinical Research and Public Health category and revised instructions; revised Research category description.
November 13, 2024: Dual-Journal Submission is live.
November 1, 2024: Added Dual-Journal Submission option.
September 30, 2024: Clarified instructions for Research Letter and Letter to the Editor categories.
April 26, 2024: Specified that Acknowledgments in the main text of Research Letters contributes to the word count.
December 13, 2023: Added requirement to include "Sex as a biological variable" paragraph.
October 25, 2023: Revised to state that uncut blots and gels will be published for any accepted manuscript effective January 1, 2024; and to require supporting data values file at first submission.
Changed requirement for quantitative graph presentation to occur at first submission.
October 3, 2023: Changed requirement for quantitative graph presentation to occur at first submission.
July 12, 2023: Added links to "How to prepare tables."
June 2, 2023: Provided alternate URL for CONSORT checklist.
April 6, 2023: Added requirement for Data Availability paragraph.
July 25, 2022: Added Supplemental material to Research Letter category.
July 2022: Added Research Letter category
May 23, 2022: Changed Letter to the Editor word limit from 400 to 850.
January 4, 2022: Removed Concise Communication category.
December 15, 2024: Added Public Health to create Clinical Research and Public Health category and revised instructions; revised Research category description.
November 1, 2024: Reorganized page so that Manuscript preparation comes first.
April 26, 2024: Specified that Acknowledgments in the main text of Research Letters contributes to the word count.
December 13, 2023: Added requirement to include "Sex as a biological variable" paragraph.
October 25, 2023: Revised to state that uncut blots and gels will be published for any accepted manuscript effective January 1, 2024; and to require supporting data values file at first submission.
July 12, 2023: Added links to "How to prepare tables" and "How to prepare Supporting data values."
June 2, 2023: Provided alternate URL for CONSORT checklist.
April 6, 2023: Added requirement for Supporting Data Values and Data Availability paragraph; and policy on repeated images.
July 25, 2022: Added supplemental material to Research Letter category.
July 13, 2022: Added Research Letter category.
June 19, 2022: Updated patient photograph requirement.
June 13, 2022: Added Research letter category.
May 23, 2022: Changed Letter to the Editor word limit from 400 to 850.
February 15, 2022: Removed Concise Communication category.
January 24, 2025: Updated AI policy for reviewer responsibilities.
December 15, 2024: Revised Clinical Medicine category as Clinical Research and Public Health.
December 2, 2024: Added announcement of publication fee change beginning January 1, 2025.
November 13, 2024: Dual-Journal Submission is live.
November 1, 2024: Added Dual-Journal Submission option.
October 9, 2024: Added guidelines for generative AI technologies.
November 14, 2023: Updated publication fees for 2024.
November 22, 2022: Added policy for submission of external reviews.
November 21, 2022: Added notice of publication fee increase from $5,200 to $5,300.
November 1, 2022: Added Misconduct allegations section.
July 13, 2022: Added Research Letter fee.
March 10, 2022: Updated so only current publication fee is shown; added language regarding requests for publicaton fee reduction.
January 4, 2022: Removed Concise Communication category.
December 20, 2021: Revised for Gold Open Access.
October 4, 2021: Added notification of changes effective with January 4, 2022, issue: all papers published under CC BY 4.0 license; publication fee change from $4,650 to $5,200 for Research and Clinical Medicine and $3,500 to $3,900 for Concise Communication.
September 15, 2021: Clarified text regarding reviewer suggestions and exclusion.