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Abstract
Originating in the thyroid, the prohormone thyroxine is converted to triiodothyronine, which is essential in brain development, growth, and metabolism. A study in this issue reveals a novel mechanism for controlling triiodothyronine production that provides the first example of enzyme activity being restored by deubiquitination.
Authors
Ronald J. Koenig
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ISSN: 0021-9738 (print), 1558-8238 (online)