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J. Fred Kolhouse, Robert H. Allen
Citation Information: J Clin Invest. 1977;60(6):1381-1392. https://doi.org/10.1172/JCI108899.
J. Fred Kolhouse, Robert H. Allen
Published December 1, 1977
Citation Information: J Clin Invest. 1977;60(6):1381-1392. https://doi.org/10.1172/JCI108899.
Abstract
Analogues of cobalamin (Cbl; vitamin B12) are prevalent in nature as a result of bacterial synthesis, and are of additional interest because of their potential use as antimetabolites and chemotherapeutic agents. We have synthesized 14 Cbl analogues containing 57Co and have compared their gastrointestinal absorption, plasma transport, and cellular retention to that of [58Co]Cbl in rabbits.
Authors
J. Fred Kolhouse, Robert H. Allen
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