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Life Span of Carbamylated Red Cells in Sickle Cell Anemia
Paul F. Milner, Samuel Charache
Paul F. Milner, Samuel Charache
Published December 1, 1973
Citation Information: J Clin Invest. 1973;52(12):3161-3171. https://doi.org/10.1172/JCI107516.
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Research Article

Life Span of Carbamylated Red Cells in Sickle Cell Anemia

Abstract

By using three isotopes of diisopropyl-phosphofluoridate ([3H]-, [14C]-, and [32P]DFP) simultaneously, the life span of red cells from 20 patients with sickle cell anemia (Hb SS) has been studied after varying degrees of carbamylation in vitro with cyanate (NCO) and carbamyl phosphate (CP). The results are expressed in terms of the red cell mean life span (MLS).

Authors

Paul F. Milner, Samuel Charache

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