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Marcos Rojkind
Citation Information: J Clin Invest. 1973;52(10):2451-2456. https://doi.org/10.1172/JCI107436.
Marcos Rojkind
Published October 1, 1973
Citation Information: J Clin Invest. 1973;52(10):2451-2456. https://doi.org/10.1172/JCI107436.
Abstract
L-Azetidine-2-carboxylic acid (AZC), an analogue of proline, has been shown to partially ameliorate hepatic cirrhosis induced in rats by CCl4. AZC caused a diminution in formation of collagen in the liver accompanied by a relative decrease in the pool of free proline. The synthesis of noncollagenous proteins in the livers of treated rats did not appear to be affected.
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Marcos Rojkind
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