Submit a comment

Performance of the right ventricle under stress: relation to right coronary flow
Harold Brooks, … , Charles W. Urschel, Edmund H. Sonnenblick
Harold Brooks, … , Charles W. Urschel, Edmund H. Sonnenblick
Published October 1, 1971
Citation Information: J Clin Invest. 1971;50(10):2176-2183. https://doi.org/10.1172/JCI106712.
View: Text | PDF
Research Article Article has an altmetric score of 1

Performance of the right ventricle under stress: relation to right coronary flow

Abstract

Right ventricular performance was studied relative to right coronary artery flow in the chloralose-anesthetized, open chest dog. The right coronary artery was cannulated for measurement and control of flow and pressure. Under control conditions, right coronary artery occlusion caused no change in cardiac output, or right and left ventricular pressures, although right ventricular contractile force fell markedly. With right coronary artery flow intact, incremental pulmonary artery obstruction caused a corresponding decline in cardiac output and elevation of right ventricular end-diastolic pressure with eventual total right ventricular failure and systemic shock. With right coronary artery occlusion, identical degrees of pulmonary artery obstruction resulted in more pronounced changes in cardiac output and right ventricular end-diastolic pressure with right ventricular failure occurring at a much lower level of right ventricular stress.

Authors

Harold Brooks, Edward S. Kirk, Pantel S. Vokonas, Charles W. Urschel, Edmund H. Sonnenblick

×

Guidelines

The Editorial Board will only consider comments that are deemed relevant and of interest to readers. The Journal will not post data that have not been subjected to peer review; or a comment that is essentially a reiteration of another comment.

  • Comments appear on the Journal’s website and are linked from the original article’s web page.
  • Authors are notified by email if their comments are posted.
  • The Journal reserves the right to edit comments for length and clarity.
  • No appeals will be considered.
  • Comments are not indexed in PubMed.

Specific requirements

  • Maximum length, 400 words
  • Entered as plain text or HTML
  • Author’s name and email address, to be posted with the comment
  • Declaration of all potential conflicts of interest (even if these are not ultimately posted); see the Journal’s conflict-of-interest policy
  • Comments may not include figures
This field is required
This field is required
This field is required
This field is required
This field is required
This field is required
Rich Text Editor, eletter_body