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Citation Information: J Clin Invest. 1971;50(1):112-118. https://doi.org/10.1172/JCI106464.
Abstract
Water diuresis was produced in anesthetized hypophysectomized, cortisone-treated dogs by infusion of 2.5% dextrose. Alpha adrenergic blockade of the left kidney produced by infusion of phenoxybenzamine in the left renal artery was associated with a significantly (P < 0.05) greater rate of urine flow (V) and free water excretion (CH2O) in the left kidney than in the right despite similar glomerular filtration rates (GFR) (17 ± 1.3 ml/min, left; 18 ±0.9 ml/min, right). Sodium excretion (UNaV) was similar in the two kidneys (3 and 5 μEq/min).
Authors
John R. Gill Jr., Alfred G. T. Casper
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