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Synthesis and release of proinsulin and insulin by isolated rat islets of Langerhans
Tomio Tanese, … , Sevim Devrim, Lillian Recant
Tomio Tanese, … , Sevim Devrim, Lillian Recant
Published July 1, 1970
Citation Information: J Clin Invest. 1970;49(7):1394-1404. https://doi.org/10.1172/JCI106357.
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Synthesis and release of proinsulin and insulin by isolated rat islets of Langerhans

Abstract

Isolated rat islets of Langerhans were incubated for 60, 120, and 180 min and the incorporation of leucine-3H into proinsulin and insulin moieties was followed. Synthesis and release of these hormones could be followed by separate extractions of islets and incubation media.

Authors

Tomio Tanese, Norman R. Lazarus, Sevim Devrim, Lillian Recant

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