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Citation Information: J Clin Invest. 1969;48(7):1266-1272. https://doi.org/10.1172/JCI106092.
Abstract
The characteristics of ribonucleic acid (RNA) degradation in intact reticulocytes have been investigated. The rate of degradation during in vitro maturation at 37°C is approximately 4% per hr. RNA degradation does not proceed at 0°C, and the rate of degradation is temperature dependent with an optimum at 50°C. The process is not dependent upon glycolysis. Although all types of RNA progressively decrease during in vivo maturation, ribosomes are degraded at a rate greater than that of soluble RNA.
Authors
Edward R. Burka
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