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Biosynthetic And structural studies of a heavy chain disease protein
Daniel Ein, … , Donald N. Buell, John L. Fahey
Daniel Ein, … , Donald N. Buell, John L. Fahey
Published April 1, 1969
Citation Information: J Clin Invest. 1969;48(4):785-793. https://doi.org/10.1172/JCI106036.
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Research Article

Biosynthetic And structural studies of a heavy chain disease protein

Abstract

A new heavy chain disease protein (γHCD-JM) has been characterized by antigenic and structural criteria. The protein belongs to the IgG3-subclass and is closely related to Fc-fragment of G3-immunoglobulins. The predominant N-terminal amino acid of this protein is glutamic acid in the uncyclized form, and that of another γHCD is glycine.

Authors

Daniel Ein, Donald N. Buell, John L. Fahey

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