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Chester A. Alper, Fred S. Rosen
Citation Information: J Clin Invest. 1967;46(12):2021-2034. https://doi.org/10.1172/JCI105691.
Chester A. Alper, Fred S. Rosen
Published December 1, 1967
Citation Information: J Clin Invest. 1967;46(12):2021-2034. https://doi.org/10.1172/JCI105691.
Abstract
The metabolic behavior of C′3 labeled with radioactive iodine was investigated in 10 normal subjects and in 20 patients with diseases in which complement is thought to play a pathophysiological role. The mean fractional catabolic rate of C′3 in normal subjects was 2.3 ± 1.0% of the plasma pool per hr, whereas the fractional catabolic rate of C′3i, the inactive conversion product of C′3 produced by complement activation, was at least five times as great.
Authors
Chester A. Alper, Fred S. Rosen
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