Citations to this article

Hostile takeover: fungal protein promotes host cell invasion
J. Andrew Alspaugh
J. Andrew Alspaugh
Published December 20, 2013
Citation Information: J Clin Invest. 2014;124(1):74-76. https://doi.org/10.1172/JCI73585.
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Hostile takeover: fungal protein promotes host cell invasion

Abstract

The ability to suppress the immune system has lead to great advances in transplant technology and treatment of autoimmune diseases. Unfortunately, the immunosuppression of these patients has led to the rise of opportunistic infections by organisms that are recalcitrant to current prophylactic strategies. One such example is the increase of mucormycosis, an invasive infection caused by filamentous fungi of the order Mucorales. In this issue of the JCI, Gebremariam and colleagues determined that spore coat homolog (CotH) proteins are required for angioinvasion and that these proteins are unique to Mucorales. Their findings provide a potential therapeutic target for prevention and treatment of mucormycosis.

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J. Andrew Alspaugh

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Citations to this article (6)

Title and authors Publication Year
Crosstalk between ROS-inflammatory gene expression axis in the progression of lung disorders.
Ashique S, Mishra N, Mantry S, Garg A, Kumar N, Gupta M, Kar SK, Islam A, Mohanto S, Subramaniyan V 		Naunyn-Schmiedeberg's archives of pharmacology 2024
Virulence traits and novel drug delivery strategies for mucormycosis post-COVID-19: a comprehensive review
Faiyazuddin M, Sophia A, Ashique S, Gholap AD, Gowri S, Mohanto S, Karthikeyan C, Nag S, Hussain A, Akhtar MS, Bakht MA, Ahmed MG, Rustagi S, Rodriguez-Morales AJ, Salas-Matta LA, Mohanty A, Bonilla-Aldana DK, Sah R 		Frontiers in immunology 2023
Resolving the equation between mucormycosis and COVID-19 disease
R Pasrija, M Naime 		Molecular Biology Reports 2022
Sensitivity of liquid‐based cytology in the diagnosis of mucormycosis in COVID ‐19 treated patients
R Kumar, M Singh, T Sagar, Bharanidharan, N Khurana, V Kumar, R Meher, V Malhotra, R Goel, S Saxena, J Kumar 		Cytopathology 2022
Mucormycosis co-infection in COVID-19 patients: An update
Alkhamiss AS, Ahmed AA, Rasheed Z, Alghsham R, Shariq A, Alsaeed T, Althwab SA, Alsagaby S, Aljohani AS, Alhumaydhi FA, Alduraibi SK, Alduraibi AK, Alhomaidan HT, Allemailem KS, Alharbi RA, Alamro SA, Alqusayer AM, Alharbi SA, Alharby TA, Almujaydil MS, Mousa AM, Alghaniam SA, Alghunaim AA, Alghamdi R, Fernández N, Al Abdulmonem W 		Open Life Sciences 2022
Genes, Pathways, and Mechanisms Involved in the Virulence of Mucorales
C Lax, C Pérez-Arques, MI Navarro-Mendoza, JT Cánovas-Márquez, G Tahiri, JA Pérez-Ruiz, M Osorio-Concepción, L Murcia-Flores, E Navarro, V Garre, FE Nicolás 		Genes & development 2020

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