Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin
Lilian I. Plotkin, … , Stavros C. Manolagas, Teresita Bellido
Lilian I. Plotkin, … , Stavros C. Manolagas, Teresita Bellido
Published November 15, 1999
Citation Information: J Clin Invest. 1999;104(10):1363-1374. https://doi.org/10.1172/JCI6800.
View: Text | PDF
Article Article has an altmetric score of 3

Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin

  • Text
  • PDF
Abstract

Glucocorticoid-induced osteoporosis may be due, in part, to increased apoptosis of osteocytes and osteoblasts, and bisphosphonates (BPs) are effective in the management of this condition. We have tested the hypothesis that BPs suppress apoptosis in these cell types. Etidronate, alendronate, pamidronate, olpadronate, or amino-olpadronate (IG9402, a bisphosphonate that lacks antiresorptive activity) at 10–9 to 10–6 M prevented apoptosis of murine osteocytic MLO-Y4 cells, whether it was induced by etoposide, TNF-α, or the synthetic glucocorticoid dexamethasone. BPs also inhibited apoptosis of primary murine osteoblastic cells isolated from calvaria. Similar antiapoptotic effects on MLO-Y4 and osteoblastic cells were seen with nanomolar concentrations of the peptide hormone calcitonin. The antiapoptotic effect of BPs and calcitonin was associated with a rapid increase in the phosphorylated fraction of extracellular signal regulated kinases (ERKs) and was blocked by specific inhibitors of ERK activation. Consistent with these in vitro results, alendronate abolished the increased prevalence of apoptosis in vertebral cancellous bone osteocytes and osteoblasts that follows prednisolone administration to mice. These results suggest that the therapeutic efficacy of BPs or calcitonin in diseases such as glucocorticoid-induced osteoporosis may be due, in part, to their ability to prevent osteocyte and osteoblast apoptosis.

Authors

Lilian I. Plotkin, Robert S. Weinstein, A. Michael Parfitt, Paula K. Roberson, Stavros C. Manolagas, Teresita Bellido

×

Total citations by year

Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1997 1991 Total
Citations: 2 6 8 15 11 19 13 19 28 37 21 38 42 32 40 39 27 43 37 41 36 32 31 27 23 10 1 2 1 681
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (681)

Title and authors Publication Year
Advancements in Bone Replacement Techniques–Potential Uses After Maxillary and Mandibular Resections Due to Medication-Related Osteonecrosis of the Jaw (MRONJ)
Bovari-Biri J, Miskei JA, Kover Z, Steinerbrunner-Nagy A, Kardos K, Maroti P, Pongracz JE
Cells 2025
Capsaicin counteracts dexamethasone-induced osteoporosis and metabolic disturbances in rats: role of AMPK/SIRT1/β-catenin/RUNX2 pathway.
Habiba ES, Fathelbab MH, Omar EM, ElAlkamy AMT, Omar W, Harby SA
Journal of molecular histology 2025
Unexpected chronic lymphocytic leukemia B cell activation by bisphosphonates.
Mazzarello AN, Gugiatti E, Cossu V, Bertola N, Bagnara D, Carta S, Ravera S, Salvetti C, Ibatici A, Ghiotto F, Colombo M, Cutrona G, Marini C, Sambuceti G, Fais F, Bruno S
Cancer Immunology, Immunotherapy 2024
Bisphosphonates for osteoporosis: from bench to clinic
Teresita Bellido
Journal of Clinical Investigation 2024
Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
Adhikari M, Kaur J, Sabol HM, Anloague A, Khan S, Kurihara N, Diaz-delCastillo M, Andreasen CM, Barnes CL, Stambough JB, Palmieri M, Reyes-Castro O, Ambrogini E, Almeida M, O\u2019Brien CA, Nookaw I, Delgado-Calle J
Research square 2024
Global Trends in Research of Programmed Cell Death in Osteoporosis: A Bibliometric and Visualized Analysis (2000–2023)
Rong Y, Liang X, Jiang K, Jia H, Li H, Lu B, Li G
Orthopaedic Surgery 2024
PTH receptor signalling, osteocytes and bone disease induced by diabetes mellitus.
Marino S, Bellido T
Nature reviews. Endocrinology 2024
Single-cell Transcriptomic Analysis Identifies Senescent Osteocytes that Trigger Bone Destruction in Breast Cancer Metastasis
Kaur J, Adhikari M, Sabol HM, Anloague A, Khan S, Kurihara N, Diaz-delCastillo M, Andreasen CM, Barnes CL, Stambough JB, Palmieri M, Reyes-Castro O, Zarrer J, Taipaleenmäki H, Ambrogini E, Almeida M, O\u2019Brien CA, Nookaw I, Delgado-Calle J
Cancer research 2024
Bisphosphonate use for glucocorticoid-induced osteoporosis in older patients with immune thrombocytopenia: a clinical perspective.
Yamasaki S
Annals of Hematology 2023
Identification of hub genes and therapeutic drugs in osteonecrosis of the femoral head through integrated bioinformatics analysis and literature mining.
Tang L, Li B, Su Q, Chen X, He R
Scientific Reports 2023
Pathogenic mechanisms of glucocorticoid-induced osteoporosis
Chen M, Fu W, Xu H, Liu CJ
Cytokine & Growth Factor Reviews 2023
Role of Cx43 on the Bone Cell Generation, Function, and Survival.
Plotkin LI, Asad I, Kritikos AE, Sanz N
2023
Comparison of the prophylactic use of ibandronate and its use in early-stage osteonecrosis in rats with steroid-induced osteonecrosis of the femoral head.
Çağlar S, Daşcı MF, Acar A, Çağlar A, Dinçel YM, Çataltepe A
2023
Treating the Side Effects of Exogenous Glucocorticoids; Can We Separate the Good From the Bad?
Pofi R, Caratti G, Ray DW, Tomlinson JW
Endocrine reviews 2023
Alendronate augments lipid A‑induced IL‑1β release by ASC‑deficient RAW264 cells via AP‑1 activation.
Watanabe N, Tamai R, Kiyoura Y
Experimental and therapeutic medicine 2023
Bcl2l1 Deficiency in Osteoblasts Reduces the Trabecular Bone Due to Enhanced Osteoclastogenesis Likely through Osteoblast Apoptosis.
Moriishi T, Kawai Y, Fukuyama R, Matsuo Y, He YW, Akiyama H, Asahina I, Komori T
International journal of molecular sciences 2023
The osteocyte as a signaling cell
J Delgado-Calle, T Bellido
Physiological reviews 2022
Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects
R Scala, F Maqoud, M Antonacci, J Dibenedetto, M Perrone, A Scilimati, K Castillo, R Latorre, D Conte, S Bendahhou, D Tricarico
Frontiers in pharmacology 2022
Protein tyrosine phosphatases in skeletal development and diseases
H Yang, L Wang, C Shigley, W Yang
Bone Research 2022
Role of the Interaction of Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors 1 and 2 in Bone-Related Cells.
Kitaura H, Marahleh A, Ohori F, Noguchi T, Nara Y, Pramusita A, Kinjo R, Ma J, Kanou K, Mizoguchi I
International journal of molecular sciences 2022
The Mechanosensory Role of Osteocytes and Implications for Bone Health and Disease States
Choi JU, Kijas AW, Lauko J, Rowan AE
Frontiers in Cell and Developmental Biology 2022
Bad to the Bone: The Effects of Therapeutic Glucocorticoids on Osteoblasts and Osteocytes.
Gado M, Baschant U, Hofbauer LC, Henneicke H
Frontiers in Endocrinology 2022
Therapeutic perspectives of exosomes in glucocorticoid-induced osteoarthrosis
Lv B, Cheng Z, Yu Y, Chen Y, Gan W, Li S, Zhao K, Yang C, Zhang Y
Frontiers in Surgery 2022
Pathways Controlling Formation and Maintenance of the Osteocyte Dendrite Network.
Wang JS, Wein MN
Current Osteoporosis Reports 2022
Partial prevention of glucocorticoid-induced osteocyte deterioration in young male mice with osteocrin gene therapy.
Mazur CM, Castro Andrade CD, Tokavanich N, Sato T, Bruce M, Brooks DJ, Bouxsein ML, Wang JS, Wein MN
iScience 2022
Advances in Our Understanding of the Mechanism of Action of Drugs (including Traditional Chinese Medicines) for the Intervention and Treatment of Osteoporosis
Lu J, Hu D, Ma C, Shuai B
Frontiers in pharmacology 2022
Effect of cyclic pamidronate administration on osteoporosis in children with β-thalassemia major: a single-center study.
El-Hawy MA, Saleh NY
2022
Medication-related osteonecrosis of the jaw: An update.
Bansal H
National Journal of Maxillofacial Surgery 2022
Tocotrienol as a Protecting Agent against Glucocorticoid-Induced Osteoporosis: A Mini Review of Potential Mechanisms.
Ekeuku SO, Mohd Ramli ES, Abdullah Sani N, Abd Ghafar N, Soelaiman IN, Chin KY
Molecules (Basel, Switzerland) 2022
Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence
Saul D, Khosla S
Endocrine reviews 2022
The Use of Hydroxyapatite Loaded with Doxycycline (HADOX) in Dentoalveolar Surgery as a Risk-Reduction Therapeutic Protocol in Subjects Treated with Different Bisphosphonate Dosages.
Sacco R, Sartoretto SC, de Brito Resende RF, de Albuquerque Calasans-Maia J, Rossi AM, de Souza Lima VH, de Almeida Barros Mourão CF, Granjeiro JM, Yates J, Calasans-Maia MD
2022
RANKL Blockade Reduces Cachexia and Bone Loss Induced by Non‐Metastatic Ovarian Cancer in Mice
F Pin, AJ Jones, JR Huot, A Narasimhan, TA Zimmers, LF Bonewald, A Bonetto
Journal of Bone and Mineral Research 2021
The molecular etiology and treatment of glucocorticoid-induced osteoporosis
CH Penga, WY Lin, KT Yeh, IH Chen, WT Wu, MD Lin
Tzu Chi Medical Journal 2021
Endogenous Glucocorticoid Metabolism in Bone: Friend or Foe
CS Martin, MS Cooper, RS Hardy
Frontiers in Endocrinology 2021
Bisphosphonates in inflammatory rheumatic diseases
P Peris, A Monegal, N Guañabens
Bone 2021
The Potential Role of Exercise Training and Mechanical Loading on Bone-Associated Skeletal Nerves
S Negri, TJ Samuel, S Lee
Journal of Bone Metabolism 2021
Biologic and pathologic aspects of osteocytes in the setting of medication-related osteonecrosis of the jaw (MRONJ)
JI Aguirre, EJ Castillo, DB Kimmel
Bone 2021
A Bisphosphonate With a Low Hydroxyapatite Binding Affinity Prevents Bone Loss in Mice After Ovariectomy and Reverses Rapidly With Treatment Cessation
AA Coffman, J BastaPljakic, RM Guerra, FH Ebetino, MW Lundy, RJ Majeska, MB Schaffler
JBMR Plus 2021
Effects of Bisphosphonates on Osseointegration of Dental Implants in Rabbit Model
RQ Yu, JY Wang, NJ Rao, L Huo, LW Zheng, M Gagat
BioMed Research International 2021
Role of osteogenic Dickkopf-1 in bone remodeling and bone healing in mice with type I diabetes mellitus
N Hildebrandt, J Colditz, C Dutra, P Goes, J Salbach-Hirsch, S Thiele, LC Hofbauer, M Rauner
Scientific Reports 2021
DCAF1-targeting microRNA-3175 activates Nrf2 signaling and inhibits dexamethasone-induced oxidative injury in human osteoblasts
J Chen, J Liang, YF Zhen, L Chang, Z Zhou, X Shen
Cell Death and Disease 2021
Alendronate-induced Perturbation of the Bone Proteome and Microenvironmental Pathophysiology
J Kim, A Yeon, SJ Parker, M Shahid, A Thiombane, E Cho, S You, H Emam, DG Kim, M Kim
International journal of medical sciences 2021
A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow‐Fed Young Adult Mice
M Palmieri, HN Kim, H GomezAcevedo, X Que, S Tsimikas, RL Jilka, SC Manolagas, JL Witztum, E Ambrogini
Journal of Bone and Mineral Research 2020
Tumour dormancy in inflammatory microenvironment: A promising therapeutic strategy for cancer-related bone metastasis
W Hu, L Zhang, Y Dong, Z Tian, Y Chen, S Dong
Cellular and Molecular Life Sciences 2020
Osteoporosis: Pathophysiology and Clinical Management
BZ Leder, MN Wein
2020
Calcitonin and Bone Physiology: In Vitro, In Vivo, and Clinical Investigations
J Xie, J Guo, Z Kanwal, M Wu, X Lv, NA Ibrahim, P Li, MA Buabeid, ES Arafa, Q Sun
International Journal of Endocrinology 2020
COL3A1, COL6A3, and SERPINH1 Are Related to Glucocorticoid-Induced Osteoporosis Occurrence According to Integrated Bioinformatics Analysis
L Li, M Yang, A Jin
Medical science monitor : international medical journal of experimental and clinical research 2020
Mitigating osteonecrosis of the jaw (ONJ) through preventive dental care and understanding of risk factors
JT Wan, DM Sheeley, MJ Somerman, JS Lee
Bone Research 2020
Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors
HN Kim, F Ponte, I Nookaew, SU Ozgurel, A Marques-Carvalho, S Iyer, A Warren, N Aykin-Burns, K Krager, VA Sardao, L Han, R de Cabo, H Zhao, RL Jilka, SC Manolagas, M Almeida
Scientific Reports 2020
Involvement of the Gut Microbiota and Barrier Function in Glucocorticoid‐Induced Osteoporosis
JD Schepper, F Collins, ND RiosArce, HJ Kang, L Schaefer, JD Gardinier, R Raghuvanshi, RA Quinn, R Britton, N Parameswaran, LR McCabe
Journal of Bone and Mineral Research 2020
Treatment options for glucocorticoid-induced osteoporosis
I Chiodini, D Merlotti, A Falchetti, L Gennari
Expert Opinion on Pharmacotherapy 2020
Updates in epidemiology, pathophysiology and management strategies of glucocorticoid-induced osteoporosis
C Iacopo, F Alberto, M Daniela, EV Cristina, G Luigi
Expert Review of Endocrinology & Metabolism 2020
Irisin Prevents Disuse‐Induced Osteocyte Apoptosis
G Storlino, G Colaianni, L Sanesi, L Lippo, G Brunetti, M Errede, S Colucci, G Passeri, M Grano
Journal of Bone and Mineral Research 2020
Building the case for the calcitonin receptor as a viable target for the treatment of glioblastoma
P Gupta, SG Furness, L Bittencourt, DL Hare, PJ Wookey
Therapeutic advances in medical oncology 2020
Bisphosphonates inhibit surface‐mediated osteogenesis
EM Lotz, CH Lohmann, BD Boyan, Z Schwartz
Journal of biomedical materials research. Part A 2020
A Biomimetic Biphasic Osteochondral Scaffold with Layer‐Specific Release of Stem Cell Differentiation Inducers for the Reconstruction of Osteochondral Defects
X Liu, Y Wei, C Xuan, L Liu, C Lai, M Chai, Z Zhang, L Wang, X Shi
Advanced Healthcare Materials 2020
In vitro and in vivo studies using non-traditional bisphosphonates
LI Plotkin, S Buvinic, J Balanta-Melo
Bone 2020
Vertebral Compression Fractures in Osteoporotic and Pathologic Bone: A Clinical Guide to Diagnosis and Management
AE Razi, SH Hershman
2020
Treatment of patients with diabetes mellitus and postmenopausal osteoporosis — difficulties of choice
EV Doskina
Rossiiskii vestnik akushera-ginekologa 2020
Therapeutic and functional approach for the treatment of patients with bone marrow edema in Rehabilitation Medicine
L Cavalli, G Falcone, T Cavalli, P Pasquetti
2020
Phenomenon of osteocyte lacunar mineralization: indicator of former osteocyte death and a novel marker of impaired bone quality?
P Milovanovic, B Busse
Endocrine Connections 2020
Glucocorticoid-Induced Bone Fragility Is Prevented in Female Mice by Blocking Pyk2/Anoikis Signaling
AY Sato, M Cregor, K McAndrews, T Li, KW Condon, LI Plotkin, T Bellido
Endocrinology 2019
Osteocytic miR21 deficiency improves bone strength independent of sex despite having sex divergent effects on osteocyte viability and bone turnover
HM Davis, PJ Deosthale, R PachecoCosta, AL Essex, EG Atkinson, MW Aref, JE Dilley, T Bellido, M Ivan, MR Allen, LI Plotkin
The FEBS journal 2019
The Activity of Peptides of the Calcitonin Family in Bone
D Naot, DS Musson, J Cornish
Physiological reviews 2019
Current Treatments and New Developments in the Management of Glucocorticoid-induced Osteoporosis
HG Raterman, IE Bultink, WF Lems
Drugs 2019
Ibandronate Treatment Before and After Implant Insertion Impairs Osseointegration in Aged Rats with Ovariectomy Induced Osteoporosis: IBANDRONATE TREATMENT IMPAIRS OSSEOINTEGRATION IN OVARIECTOMIZED RATS
EM Lotz, DJ Cohen, RA Ellis, JS Wayne, Z Schwartz, BD Boyan
JBMR Plus 2019
High mobility group box 1 protein regulates osteoclastogenesis through direct actions on osteocytes and osteoclasts in vitro
HM Davis, S Valdez, L Gomez, P Malicky, FA White, MA Subler, JJ Windle, JP Bidwell, A Bruzzaniti, LI Plotkin
Journal of Cellular Biochemistry 2019
Zoledronic acid plus methylprednisolone versus zoledronic acid or placebo in symptomatic knee osteoarthritis: a randomized controlled trial
G Cai, LL Laslett, D Aitken, F Cicuttini, L March, C Hill, T Winzenberg, G Jones
Therapeutic Advances in Musculoskeletal Diseases 2019
Development and characterization of supramolecular calcitonin assembly and assessment of its interactions with the bone remodelling process
K Manglani, V Vijayan, C Pathak, M Khandelwal, P Singh, S Chellappa, VK Yadav, A Surolia, S Gupta
Bone 2019
Immobilization of BMP‐2, BMP‐7 and alendronic acid on titanium surfaces: Adhesion, proliferation and differentiation of bone marrow‐derived stem cells
PW Kämmerer, AM Pabst, M Dau, H Staedt, B AlNawas, M Heller
Journal of biomedical materials research. Part A 2019
Mechanisms of palmitate-induced lipotoxicity in osteocytes
AA Saedi, S Bermeo, L Plotkin, DE Myers, G Duque
Bone 2019
Alendronate inhibits osteocyte apoptosis and inflammation via IL ‐6, inhibiting bone resorption in periapical lesions of ovariectomized rats
RA Silva, AP SousaPereira, MP Lucisano, PC Romualdo, FW PaulaSilva, A Consolaro, LA Silva, P NelsonFilho
International Endodontic Journal 2019
The effect of risedronate on orthodontic tooth movement in ovariectomized rats
D Wu, B Meng, Y Cheng, L Gan, P Huang, Y Cao
Archives of Oral Biology 2019
Osteosarcopenia: Bone, Muscle and Fat Interactions
G Duque
2019
Osteoclast Immunosuppressive Effects in Multiple Myeloma: Role of Programmed Cell Death Ligand 1
YT Tai, SF Cho, KC Anderson
Frontiers in immunology 2018
Glucocorticoid Excess in Bone and Muscle
AY Sato, M Peacock, T Bellido
Clinical Reviews in Bone and Mineral Metabolism 2018
Molecular mechanisms of glucocorticoids on skeleton and bone regeneration after fracture
Y Hachemi, AE Rapp, AK Picke, G Weidinger, A Ignatius, J Tuckermann
Journal of Molecular Endocrinology 2018
Pharmacological management of X-linked hypophosphataemia: Pharmacological management of X-linked hypophosphataemia
EA Imel, KE White
British Journal of Clinical Pharmacology 2018
Autophagy as a target for glucocorticoid-induced osteoporosis therapy
G Shen, H Ren, Q Shang, T Qiu, X Yu, Z Zhang, J Huang, W Zhao, Y Zhang, D Liang, X Jiang
Cellular and Molecular Life Sciences 2018
Oxidation-specific epitopes restrain bone formation
E Ambrogini, X Que, S Wang, F Yamaguchi, RS Weinstein, S Tsimikas, SC Manolagas, JL Witztum, RL Jilka
Nature Communications 2018
Evaluation of mandibular cortical bone ratio on computed tomography images in patients taking bisphosphonates
CH Koo, JH Lee
Maxillofacial Plastic and Reconstructive Surgery 2018
Positive Effects of Bisphosphonates on Osteogenic Differentiation in Patient-Derived Mesenchymal Stem Cells for the Treatment of Osteoporosis
M Cha, KM Lee, JH Lee
Tissue Engineering and Regenerative Medicine 2018
Skeletal accumulation of fluorescently tagged zoledronate is higher in animals with early stage chronic kidney disease
EA Swallow, MW Aref, N Chen, I Byiringiro, MA Hammond, BP McCarthy, PR Territo, MM Kamocka, S Winfree, KW Dunn, SM Moe, MR Allen
Osteoporosis International 2018
Cytoprotective effect of flavonoid-induced autophagy on bisphosphonate mediated cell death in osteoblast
JH Kim, HM Kang, SB Yu, JM Song, CH Kim, BJ Kim, BS Park, SH Shin, IR Kim
Journal of Cellular Biochemistry 2018
Role of bisphosphonates in the management of acute Charcot foot
H Durgia, J Sahoo, S Kamalanathan, R Palui, K Sridharan, H Raj
World journal of diabetes 2018
FoxO1 expression in osteoblasts modulates bone formation through resistance to oxidative stress in mice
Y Zhang, Y Xiong, J Zhou, N Xin, Z Zhu, Y Wu
Biochemical and Biophysical Research Communications 2018
Anabolic and antiresorptive actions of locally delivered bisphosphonates for bone repair: A review
I Qayoom, DB Raina, A Širka, Š Tarasevičius, M Tägil, A Kumar, L Lidgren
Bone & joint research 2018
Effects of alendronate for treatment of glucocorticoid-induced osteoporosis: A meta-analysis of randomized controlled trials
YK Wang, Y Zhang, SQ Qin, X Wang, T Ma, JB Guo, C Zhu, ZJ Luo
Medicine 2018
Comparative anti-fracture effectiveness of different oral anti-osteoporosis therapies based on “real-world” data: a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database
S Khalid, S Calderón-Larrañaga, S Hawley, S Ali, A Judge, N Arden, TV Staa, C Cooper, K Javaid, D Prieto-Alhambra
Clinical epidemiology 2018
Pamidronate decreases bilirubin-impaired cell death and improves dentinogenic dysfunction of stem cells from human deciduous teeth
H Yamaza, S Sonoda, K Nonaka, T Kukita, T Yamaza
Stem Cell Research & Therapy 2018
Aging and Aging-Related Diseases: Mechanisms and Interventions
Z Wang
2018
Glucocorticoids and Bone: Consequences of Endogenous and Exogenous Excess and Replacement Therapy
RS Hardy, H Zhou, MJ Seibel, MS Cooper
Endocrine reviews 2018
Plastic and Thoracic Surgery, Orthopedics and Ophthalmology
MA Shiffman, M Low
2018
Mechanical, hormonal and metabolic influences on blood vessels, blood flow and bone
RD Prisby
Journal of Endocrinology 2017
Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoanabolism
Y Shao, S Hernandez-Buquer, P Childress, KR Stayrook, MB Alvarez, H Davis, LI Plotkin, Y He, KW Condon, DB Burr, SJ Warden, AG Robling, FC Yang, RC Wek, MR Allen, JP Bidwell
Endocrinology 2017
Sex-Dependent, Osteoblast Stage-Specific Effects of Progesterone Receptor on Bone Acquisition: PRCKO IN MSCS POTENTIATES BONE ACCRUAL
ZA Zhong, A Kot, YA Lay, H Zhang, J Jia, NE Lane, W Yao
Journal of Bone and Mineral Research 2017
Matrix Metalloproteinase Inhibitors as Investigational and Therapeutic Tools in Unrestrained Tissue Remodeling and Pathological Disorders.
Liu J, Khalil RA
Progress in molecular biology and translational science 2017
Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia.
Chen J, Khalil RA
Progress in molecular biology and translational science 2017
Wnt Signaling in Kidney Development and Disease
Wang Y, Zhou CJ, Liu Y
Progress in molecular biology and translational science 2017
Wnt Signaling in Hematological Malignancies.
Grainger S, Traver D, Willert K
Progress in molecular biology and translational science 2017
Matrix Metalloproteinases in Myocardial Infarction and Heart Failure
DeLeon-Pennell KY, Meschiari CA, Jung M, Lindsey ML
Progress in molecular biology and translational science 2017
Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis
TW Fowler, C Acevedo, CM Mazur, F Hall-Glenn, AJ Fields, HA Bale, RO Ritchie, JC Lotz, TP Vail, T Alliston
Scientific Reports 2017
Connexin37 deficiency alters organic bone matrix, cortical bone geometry, and increases Wnt/β-catenin signaling
R Pacheco-Costa, JR Kadakia, EG Atkinson, JM Wallace, LI Plotkin, RD Reginato
Bone 2017
Treatment Advances in Chronic Non-Bacterial Osteomyelitis and Other Autoinflammatory Bone Conditions
Y Zhao, RM Laxer, PJ Ferguson
Current Treatment Options in Rheumatology 2017
What Animal Models Have Taught Us About the Safety and Efficacy of Bisphosphonates in Chronic Kidney Disease
MR Allen, MW Aref
Current Osteoporosis Reports 2017
Effects of teriparatide versus alendronate for treatment of postmenopausal osteoporosis: A meta-analysis of randomized controlled trials
YK Wang, SQ Qin, T Ma, W Song, RQ Jiang, JB Guo, K Li, YM Zhang
Medicine 2017
Enhanced Osteogenic Differentiation in Zoledronate-Treated Osteoporotic Patients
LD Carbonare, M Mottes, G Malerba, A Mori, M Zaninotto, M Plebani, A Dellantonio, M Valenti
International journal of molecular sciences 2017
Impairment of cold injury-induced muscle regeneration in mice receiving a combination of bone fracture and alendronate treatment
S Kawada, A Harada, N Hashimoto, A Asakura
PloS one 2017
Sex dimorphic regulation of osteoprogenitor progesterone in bone stromal cells
A Kot, ZA Zhong, H Zhang, YA Lay, NE Lane, W Yao
Journal of Molecular Endocrinology 2017
High glucose alters the secretome of mechanically stimulated osteocyte-like cells affecting osteoclast precursor recruitment and differentiation
M Maycas, MT Portolés, MC Matesanz, I Buendía, J Linares, MJ Feito, D Arcos, M Vallet-Regí, LI Plotkin, P Esbrit, AR Gortázar
Journal of Cellular Physiology 2017
Cytoprotective effects of melatonin on zoledronic acid-treated human osteoblasts
F Camacho-Alonso, I Urrutia-Rodríguez, D Oñate-Cabrerizo, RE Oñate-Sánchez, FJ Rodríguez-Lozano
Journal of Cranio-Maxillofacial Surgery 2017
Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis of the femoral head via the Akt/Bad/Bcl-2 signal pathway
SC Tao, T Yuan, BY Rui, ZZ Zhu, SC Guo, CQ Zhang
Theranostics 2017
Dendritic polyglycerol anions for the selective targeting of native and inflamed articular cartilage
S Reimann, T Schneider, P Welker, F Neumann, K Licha, G Schulze-Tanzil, W Wagermaier, P Fratzl, R Haag
Journal of Materials Chemistry B 2017
Protective effect of low-dose risedronate against osteocyte apoptosis and bone loss in ovariectomized rats
T Ye, P Cao, J Qi, Q Zhou, DS Rao, S Qiu, V Geoffroy
PloS one 2017
Studies regarding the induced thermal degradation, kinetic analysis and possible interactions with various excipients of an osseointegration agent: zoledronic acid
P Albu, M Budiul, M Mateescu, V Chiriac, G Vlase, T Vlase
Journal of Thermal Analysis and Calorimetry 2017
Osteonecrosis
AR Zorzi, JB de Miranda
Osteonecrosis 2017
Osteoblast as a target of anti-osteoporotic treatment
A Corrado, ER Sanpaolo, SD Bello, FP Cantatore
Postgraduate Medicine 2017
A supplement-free osteoclast-osteoblast co-culture for pre-clinical application
S Schulze, D Wehrum, P Dieter, U Hempel
Journal of Cellular Physiology 2017
Bone Toxicology
SY Smith, A Varela, R Samadfam
Bone Toxicology 2017
Response of trabecular bone, thyroid C and follicular cells to synthetic salmon calcitonin in middle-aged orchidectomized male rats
B Filipović, B Šošić-Jurjević, V Ajdžanović, J Živanović, N Ristić, S Trifunović, V Milošević
Journal of Anatomy 2017
Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases.
Sato AY, Richardson D, Cregor M, Davis HM, Au ED, McAndrews K, Zimmers TA, Organ JM, Peacock M, Plotkin LI, Bellido T
Endocrinology 2017
Protection from Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin
AY Sato, M Cregor, J Delgado-Calle, KW Condon, MR Allen, M Peacock, LI Plotkin, T Bellido
Journal of Bone and Mineral Research 2016
Osteocytic signalling pathways as therapeutic targets for bone fragility
LI Plotkin, T Bellido
Nature Reviews Endocrinology 2016
Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement
JA Siddiqui, NC Partridge
Physiology (Bethesda, Md.) 2016
Cancer Treatment and Research
H Eda, L Santo, GD Roodman, N Raje
Cancer treatment and research 2016
Zoledronic acid increases the circulating soluble RANKL level in mice, with a further increase in lymphocyte-derived soluble RANKL in zoledronic acid- and glucocorticoid-treated mice stimulated with bacterial lipopolysaccharide
T Abe, T Sato, S Kokabu, N Hori, Y Shimamura, T Sato, T Yoda
Cytokine 2016
Zoledronate for Osteogenesis imperfecta: evaluation of safety profile in children
C Kumar, I Panigrahi, AS Aradhya, BL Meena, N Khandelwal
Journal of Pediatric Endocrinology and Metabolism 2016
Blood flow controls bone vascular function and osteogenesis
SK Ramasamy, AP Kusumbe, M Schiller, D Zeuschner, MG Bixel, C Milia, J Gamrekelashvili, A Limbourg, A Medvinsky, MM Santoro, FP Limbourg, RH Adams
Nature Communications 2016
Osteonecrosis of the Jaw—a Bone Site-Specific Effect of Bisphosphonates
JA Vermeer, GA Renders, V Everts
Current Osteoporosis Reports 2016
Pamidronate Down-regulates Tumor Necrosis Factor-alpha Induced Matrix Metalloproteinases Expression in Human Intervertebral Disc Cells
YM Kang, SH Hong, JH Yang, JC Oh, JO Park, BH Lee, SY Lee, HS Kim, HM Lee, SH Moon
Journal of Bone Metabolism 2016
Cell Death in Chondrocytes, Osteoblasts, and Osteocytes
T Komori
International journal of molecular sciences 2016
Endocrinology: Adult and Pediatric
M Gurnell, TJ Visser, P Beck-Peccoz, VK Chatterjee
Endocrinology: Adult and Pediatric 2016
Stiffness and strength of bone in osteoporotic patients treated with varying durations of oral bisphosphonates
J Ward, C Wood, K Rouch, D Pienkowski, HH Malluche
Osteoporosis International 2016
Osteoporosis in Older Persons
JA Cauley
Osteoporosis in Older Persons 2016
Principles of Osteoimmunology
DH White, R Kocijan
Principles of Osteoimmunology 2016
Effects of drug discontinuation after short-term daily alendronate administration on osteoblasts and osteocytes in mice
K Tsuboi, T Hasegawa, T Yamamoto, M Sasaki, H Hongo, PH de Freitas, T Shimizu, M Takahata, K Oda, T Michigami, M Li, Y Kitagawa, N Amizuka
Histochemistry and Cell Biology 2016
The effect of vitamin D and bisphosphonate on fracture healing: An experimental study
NH Aydoğan, İ Özel, S İltar, T Kara, A Özmeriç, KB Alemdaroğlu
Journal of Clinical Orthopaedics and Trauma 2016
OSU53 Rescues Human OB-6 Osteoblastic Cells from Dexamethasone through Activating AMPK Signaling
D Xu, W Zhao, X Zhu, J Fan, S Cui, Y Sun, X Chen, W Liu, Z Cui, C Cao
PloS one 2016
Overexpression of BCLXL in Osteoblasts Inhibits Osteoblast Apoptosis and Increases Bone Volume and Strength: BCLXL OVEREXPRESSION INCREASES BONE WITH STRENGTH
T Moriishi, R Fukuyama, T Miyazaki, T Furuichi, M Ito, T Komori
Journal of Bone and Mineral Research 2016
Avenanthramides Prevent Osteoblast and Osteocyte Apoptosis and Induce Osteoclast Apoptosis in Vitro in an Nrf2-Independent Manner
G Pellegrini, C Morales, T Wallace, L Plotkin, T Bellido
Nutrients 2016
Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase
JB Rodriguez, BN Falcone, SH Szajnman
Expert Opinion on Drug Discovery 2016
Role of microcracks in the pathogenesis of bisphosphonate-related osteonecrosis of the jaw
JW Kim, ME Landayan, JY Lee, JC Tatad, SJ Kim, MR Kim, IH Cha
Clinical Oral Investigations 2016
Revisiting bone targeting potential of novel hydroxyapatite based surface modified PLGA nanoparticles of risedronate: Pharmacokinetic and biochemical assessment
P Rawat, I Ahmad, SC Thomas, S Pandey, D Vohora, S Gupta, FJ Ahmad, S Talegaonkar
International Journal of Pharmaceutics 2016
The effect of alendronate soaking and ultraviolet treatment on bone-implant interface
HS Kim, JI Lee, SS Yang, BS Kim, BC Kim, J Lee
Clinical Oral Implants Research 2016
The role of the wnt/β-catenin signaling pathway in formation and maintenance of bone and teeth
P Duan, LF Bonewald
The International Journal of Biochemistry & Cell Biology 2016
Akt drives buffalo casein derived novel peptide mediated osteoblast differentiation
S Reddi, N Kumar, R Vij, SB Mada, S Kapila, R Kapila
The Journal of Nutritional Biochemistry 2016
Defining the role of bisphosphonates for osteonecrosis of the knee: a systematic review
RW Jordan, AD Jones, AJ Pearse
Current Orthopaedic Practice 2016
Structural Biology of Calcitonin: From Aqueous Therapeutic Properties to Amyloid Aggregation
K Kamgar-Parsi, J Tolchard, B Habenstein, A Loquet, A Naito, A Ramamoorthy
Israel Journal of Chemistry 2016
Endocrinology
C Napier, SH Pearce
Endocrinology 2016
Cadmium modulates hematopoietic stem and progenitor cells and skews toward myelopoiesis in mice
Y Zhang, X Yu, S Sun, Q Li, Y Xie, Q Li, Y Zhao, J Pei, W Zhang, P Xue, Z Zhou, Y Zhang
Toxicology and Applied Pharmacology 2016
Alendronate Can Improve Bone Alterations in Experimental Diabetes by Preventing Antiosteogenic, Antichondrogenic, and Proadipocytic Effects of AGEs on Bone Marrow Progenitor Cells
SR Chuguransky, AM Cortizo, AD McCarthy
BioMed Research International 2016
Effect of buffalo casein-derived novel bioactive peptides on osteoblast differentiation
S Reddi, VP Shanmugam, KS Tanedjeu, S Kapila, R Kapila
European Journal of Nutrition 2016
microRNA-25 targets PKCζ and protects osteoblastic cells from dexamethasone via activating AMPK signaling
J Fan, W Liu, X Zhu, H Yi, S Cui, J Zhao, Z Cui
Oncotarget 2016
miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone
J Fan, J Ruan, W Liu, L Zhu, X Zhu, H Yi, S Cui, J Zhao, Z Cui
Oncotarget 2016
Hypoxia mediates osteocyte ORP150 expression and cell death in vitro
M Montesi, K Jähn, L Bonewald, S Stea, B Bordini, A Beraudi
Molecular medicine reports 2016
Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy
K Hartmann, M Koenen, S Schauer, S Wittig-Blaich, M Ahmad, U Baschant, JP Tuckermann
Physiological reviews 2016
PTHrP-Derived Peptides Restore Bone Mass and Strength in Diabetic Mice: Additive Effect of Mechanical Loading: PTHrP-DERIVED PEPTIDES RESTORE BONE MASS IN DIABETIC MICE
M Maycas, KA McAndrews, AY Sato, GG Pellegrini, DM Brown, MR Allen, LI Plotkin, AR Gortazar, P Esbrit, T Bellido
Journal of Bone and Mineral Research 2016
Pediatric Lower Limb Deformities
S Sabharwal
2016
Calcitonin, the forgotten hormone: does it deserve to be forgotten?
AJ Felsenfeld, BS Levine
Clinical Kidney Journal 2015
Dissecting the multiple myeloma-bone microenvironment reveals new therapeutic opportunities
G Shay, L Hazlehurst, CC Lynch
Journal of Molecular Medicine 2015
American Society of Biomechanics Journal of Biomechanics Award 2013: Cortical bone tissue mechanical quality and biological mechanisms possibly underlying atypical fractures
JR Geissler, D Bajaj, JC Fritton
Journal of Biomechanics 2015
Multi-level characterization of human femoral cortices and their underlying osteocyte network reveal trends in quality of young, aged, osteoporotic and antiresorptive-treated bone
P Milovanovic, EA Zimmermann, C Riedel, A Scheidt, L Herzog, M Krause, D Djonic, M Djuric, K Püschel, M Amling, RO Ritchie, B Busse
Biomaterials 2015
Prevention of glucocorticoid induced-apoptosis of osteoblasts and osteocytes by protecting against endoplasmic reticulum (ER) stress in vitro and in vivo in female mice
AY Sato, X Tu, KA McAndrews, LI Plotkin, T Bellido
Bone 2015
Dexamethasone-induced apoptosis of osteocytic and osteoblastic cells is mediated by TAK1 activation
H Ding, T Wang, D Xu, B Cha, J Liu, Y Li
Biochemical and Biophysical Research Communications 2015
Bisphosphonates and their influence on fracture healing: a systematic review
H Molvik, W Khan
Osteoporosis International 2015
Bisphosphonate treatment of type I diabetic mice prevents early bone loss but accentuates suppression of bone formation: ALENDRONATE RESCUES DIABETIC BONE LOSS
LM Coe, SA Tekalur, Y Shu, MJ Baumann, LR McCabe
Journal of Cellular Physiology 2015
Connexins and pannexins in the skeleton: gap junctions, hemichannels and more
LI Plotkin, JP Stains
Cellular and Molecular Life Sciences 2015
Effects of Alendronate Sodium Content on the Interface Strengths of Composite Acrylic Bone Cement
DY Song, XZ Mao, M Ding, JD Ni
International Journal of Endocrinology 2015
99mTC-Methylene diphosphonate uptake at injury site correlates with osteoblast differentiation and mineralization during bone healing in mice
ZA Zhong, A Peck, S Li, J VanOss, J Snider, CJ Droscha, TA Chang, BO Williams
Bone Research 2015
Coupling Hydroxyapatite Nanocrystals with Lactoferrin as a Promising Strategy to Fine Regulate Bone Homeostasis
M Montesi, S Panseri, M Iafisco, A Adamiano, A Tampieri, D Heymann
PloS one 2015
Bone Cancer
PG Fournier, P Juárez, TA Guise
Bone Cancer 2015
Inhibition of Osteocyte Apoptosis Prevents the Increase in Osteocytic Receptor Activator of Nuclear Factor κB Ligand (RANKL) but Does Not Stop Bone Resorption or the Loss of Bone Induced by Unloading
LI Plotkin, AR Gortazar, HM Davis, KW Condon, H Gabilondo, M Maycas, MR Allen, T Bellido
The Journal of biological chemistry 2015
The Effect of Local Delivery Doxycycline and Alendronate on Bone Repair
PH Limirio, FS Rocha, JD Batista, JC Guimarães-Henriques, GB de Melo, P Dechichi
AAPS PharmSciTech 2015
Concentration-dependent effects of alendronate and pamidronate functionalized gold nanoparticles on osteoclast and osteoblast viability: CONNERS, BHETHANABOTLA, AND GUPTA
CM Conners, VR Bhethanabotla, VK Gupta
Journal of Biomedical Materials Research Part B Applied Biomaterials 2015
Alendronate–calcium phosphate hybrid films promoted the osteoblast differentiation and inhibited osteoclastogenic activity
WK Yang, EJ Chang, WK Lee
Journal of Industrial and Engineering Chemistry 2015
Mechanical loading up-regulates early remodeling signals from osteocytes subjected to physical damage
C Liu, X Zhang, M Wu, L You
Journal of Biomechanics 2015
Medication-Related Osteonecrosis of the Jaw
MR Allen
Oral and Maxillofacial Surgery Clinics of North America 2015
Ameliorating effect of combination of simvastatin and residronate on glucocorticoid induced osteoporosis model in rats
S Ahmed, ED Alaa, AM Ahmed
AFR J PHARM PHARMACO 2015
Blistering Diseases
DF Murrell
2015
Connexin 43 hemichannels and intracellular signaling in bone cells
LI Plotkin
Frontiers in physiology 2014
Apoptotic Osteocytes and the Control of Targeted Bone Resorption
LI Plotkin
Current Osteoporosis Reports 2014
Advanced Glycation End Products Play Adverse Proinflammatory Activities in Osteoporosis
R Sanguineti, A Puddu, F Mach, F Montecucco, GL Viviani
Mediators of Inflammation 2014
Glucocorticoids and bone: local effects and systemic implications
H Henneicke, SJ Gasparini, TC Brennan-Speranza, H Zhou, MJ Seibel
Trends in Endocrinology & Metabolism 2014
Modifying the osteoblastic niche with zoledronic acid in vivo—Potential implications for breast cancer bone metastasis
MT Haider, I Holen, TN Dear, K Hunter, HK Brown
Bone 2014
Pharmacological management of osteogenesis.
Nardone V, D'Asta F, Brandi ML
2014
Effects of clodronate and alendronate on osteoclast and osteoblast co-cultures on silk–hydroxyapatite films
RS Hayden, M Vollrath, DL Kaplan
Acta Biomaterialia 2014
Bisphosphonates and bone quality
M Pazianas, S der Geest, P Miller
BoneKEy Reports 2014
Osteoblastic protein tyrosine phosphatases inhibition and connexin 43 phosphorylation by alendronate
V Lezcano, T Bellido, LI Plotkin, R Boland, S Morelli
Experimental Cell Research 2014
Osteoblastic cell secretome: A novel role for progranulin during risedronate treatment
M Romanello, E Piatkowska, G Antoniali, L Cesaratto, C Vascotto, RV Iozzo, D Delneri, FL Brancia
Bone 2014
Bcl2 deficiency activates FoxO through Akt inactivation and accelerates osteoblast differentiation
T Moriishi, Y Kawai, H Komori, S Rokutanda, Y Eguchi, Y Tsujimoto, I Asahina, T Komori
PloS one 2014
Controlled delivery of zoledronate improved bone formation locally in vivo
W Gou, X Wang, J Peng, Q Lu, Y Wang, A Wang, Q Guo, X Gao, W Xu, S Lu
PloS one 2014
Lactoferrin inhibits apoptosis through insulin-like growth factor I in primary rat osteoblasts
J Hou, E Chen, S Wei, F Lin, Q Lin, X Lan, Y Xue, M Wu
Acta Pharmacologica Sinica 2014
Porous NiTi shape memory alloys produced by SHS: microstructure and biocompatibility in comparison with Ti2Ni and TiNi3
P Bassani, S Panseri, A Ruffini, M Montesi, M Ghetti, C Zanotti, A Tampieri, A Tuissi
Journal of Materials Science: Materials in Medicine 2014
The role of muscle loading on bone (Re)modeling at the developing enthesis
AM Tatara, JH Lipner, R Das, HM Kim, N Patel, E Ntouvali, MJ Silva, S Thomopoulos
PloS one 2014
Bisphosphonates: Pharmacology and Clinical Approach to Their Use in Equine Osteoarticular Diseases
SA Soto, AC Barbará
Journal of Equine Veterinary Science 2014
Osteocytes and Osteoclasts, a Relationship Under Strain
AD Bakker, V Everts
Clinical Reviews in Bone and Mineral Metabolism 2014
Does locally delivered Zoledronate influence peri-implant bone formation? – Spatio-temporal monitoring of bone remodeling in vivo
U Kettenberger, J Ston, E Thein, P Procter, DP Pioletti
Biomaterials 2014
Treatment of osteoporosis: current state of the art
I Hamrick, S Schrager, AM Nye
Wiener Medizinische Wochenschrift 2014
Pharmacological management of osteogenesis
V Nardone, F D'Asta, ML Brandi
Clinics (São Paulo, Brazil) 2014
High Bone Mass in Mice Lacking Cx37 Because of Defective Osteoclast Differentiation
R Pacheco-Costa, I Hassan, RD Reginato, HM Davis, A Bruzzaniti, MR Allen, LI Plotkin
The Journal of biological chemistry 2014
Synergistic effects of bisphosphonate and calcium phosphate nanoparticles on peri-implant bone responses in osteoporotic rats
HS Alghamdi, R Bosco, SK Both, M Iafisco, SC Leeuwenburgh, JA Jansen, JJ van Beucken
Biomaterials 2014
Local application of zoledronate enhances miniscrew implant stability in dogs
C Cuairán, PM Campbell, E Kontogiorgos, RW Taylor, AC Melo, PH Buschang
American Journal of Orthodontics and Dentofacial Orthopedics 2014
The BRC Canopy
K Wesseling-Perry
The American Journal of Pathology 2014
Lethal cervical abscess following bisphosphonate related osteonecrosis of the jaw
C Kaehling, P Streckbein, D Schmermund, M Henrich, D Burchert, S Gattenloehner, HP Howaldt, JF Wilbrand
Journal of Cranio-Maxillofacial Surgery 2014
Parathyroid Hormone Receptor Signaling Induces Bone Resorption in the Adult Skeleton by Directly Regulating the RANKL Gene in Osteocytes
AN Ben-awadh, J Delgado-Calle, X Tu, K Kuhlenschmidt, MR Allen, LI Plotkin, T Bellido
Endocrinology 2014
El hueso en las enfermedades endocrinas y nutricionales
EJ Gimeno, MC Berdonces
El hueso en las enfermedades endocrinas y nutricionales 2014
CCL7 Is a Protective Factor Secreted by Mechanically Loaded Osteocytes
Y Kitase, S Lee, J Gluhak-Heinrich, ML Johnson, SE Harris, LF Bonewald
Journal of dental research 2014
Activation of p38 MAPK-regulated Bcl-xL signaling increases survival against zoledronic acid-induced apoptosis in osteoclast precursors
TW Tai, FC Su, CY Chen, IM Jou, CF Lin
Bone 2014
Comment on Osteocytes: Masters Orchestrators of Bone
LI Plotkin, T Bellido
Calcified Tissue International 2014
Reference Module in Biomedical Sciences
DL Sackett, RB Haynes
2014
Alendronate as an Effective Treatment for Bone Loss and Vascular Calcification in Kidney Transplant Recipients
M Okamoto, S Yamanaka, W Yoshimoto, T Shigematsu
Journal of Transplantation 2014
Controlled Delivery of Zoledronate Improved Bone Formation Locally In Vivo
W Gou, X Wang, J Peng, Q Lu, Y Wang, A Wang, Q Guo, X Gao, W Xu, S Lu, L Malaval
PloS one 2014
The Role of Muscle Loading on Bone (Re)modeling at the Developing Enthesis
AM Tatara, JH Lipner, R Das, HM Kim, N Patel, E Ntouvali, MJ Silva, S Thomopoulos, D Heymann
PloS one 2014
Bcl2 Deficiency Activates FoxO through Akt Inactivation and Accelerates Osteoblast Differentiation
T Moriishi, Y Kawai, H Komori, S Rokutanda, Y Eguchi, Y Tsujimoto, I Asahina, T Komori, IV Lebedeva
PloS one 2014
Shifting paradigms on the role of connexin43 in the skeletal response to mechanical load
Shane A Lloyd, Alayna E Loiselle, Yue Zhang, Henry J Donahue
Journal of Bone and Mineral Research 2014
Effects of Osteocyte Apoptosis on Bone Cell Proliferation and Recruitment
, SH Ko
2014
Shifting Paradigms on the Role of Connexin43 in the Skeletal Response to Mechanical Load
Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ
Journal of Bone and Mineral Research 2014
FoxOs attenuate bone formation by suppressing Wnt signaling
Srividhya Iyer, Elena Ambrogini, Shoshana M. Bartell, Li Han, Paula Roberson, Rafael de Cabo, Robert L. Jilka, Robert Weinstein, Charles O'Brien, Stavros Manolagas, Maria Almeida
Journal of Clinical Investigation 2013
The osteocyte: an endocrine cell ... and more
Sarah L Dallas, Matthew Prideaux, Lynda F Bonewald
2013
Non-Nuclear–Initiated Actions of the Estrogen Receptor Protect Cortical Bone Mass
SM Bartell, L Han, H Kim, SH Kim, JA Katzenellenbogen, BS Katzenellenbogen, KL Chambliss, PW Shaul, PK Roberson, RS Weinstein, RL Jilka, M Almeida, SC Manolagas
Molecular Endocrinology 2013
Review of New Guidelines for the Management of Glucocorticoid Induced Osteoporosis
SR Venuturupalli, W Sacks
Current Osteoporosis Reports 2013
Osteocyte-Driven Bone Remodeling
T Bellido
Calcified Tissue International 2013
Feeding blueberry diets to young rats dose-dependently inhibits bone resorption through suppression of RANKL in stromal cells
J Zhang, OP Lazarenko, J Kang, ML Blackburn, MJ Ronis, TM Badger, JR Chen
PloS one 2013
Glucocorticoids and Osteocyte Autophagy
W Yao, W Dai, JX Jiang, NE Lane
Bone 2013
Beyond gap junctions: Connexin43 and bone cell signaling
LI Plotkin, T Bellido
Bone 2013
Activated protein C differentially regulates both viability and differentiation of osteoblasts mediated by bisphosphonates
YJ Lee, JK Jeong, JW Seol, M Xue, C Jackson, SY Park
Experimental & molecular medicine 2013
An In Vitro Assessment of Fibroblast and Osteoblast Response to Alendronate-Modified Titanium and the Potential for Decreasing Fibrous Encapsulation
X Hu, KG Neoh, Z Shi, ET Kang, W Wang
Tissue Engineering Part A 2013
Documenting the Use of Calcium Supplements with Oral Bisphosphonates
AM Nye, I Hamrick, A Rauch, MW Pound, PS Shelton
The Consultant Pharmacist 2013
Effects of minodronate on cortical bone response to mechanical loading in rats
K Nagira, H Hagino, Y Kameyama, R Teshima
Bone 2013
Mechanical Induction of BMP-7 in Osteocyte Blocks Glucocorticoid-Induced Apoptosis Through PI3K/AKT/GSK3β Pathway
Z Wang, J Guo
Cell Biochemistry and Biophysics 2013
Risedronate increases osteoblastic differentiation and function through connexin43
HM Jeong, YH Jin, YH Choi, JO Chung, DH Cho, MY Chung, R Civitelli, DJ Chung, KY Lee
Biochemical and Biophysical Research Communications 2013
Icariin Protects Against Glucocorticoid-Induced Osteoporosis In Vitro and Prevents Glucocorticoid-Induced Osteocyte Apoptosis In Vivo
R Feng, L Feng, Z Yuan, D Wang, F Wang, B Tan, S Han, T Li, D Li, Y Han
Cell Biochemistry and Biophysics 2013
Calcitonin: Physiology or fantasy?
RA Davey, DM Findlay
Journal of Bone and Mineral Research 2013
Healing of the bone with anti-fracture drugs
ML Brandi
Expert Opinion on Pharmacotherapy 2013
Glucocorticoid-induced osteoporosis: mechanisms, management, and future perspectives
MJ Seibel, MS Cooper, H Zhou
The Lancet Diabetes & Endocrinology 2013
Molecular determinants of glucocorticoid actions in inflammatory joint diseases
U Baschant, S Culemann, J Tuckermann
Molecular and Cellular Endocrinology 2013
Osteoanabolic effect of alendronate and zoledronate on bone marrow stromal cells (BMSCs) isolated from aged female osteoporotic patients and its implications for their mode of action in the treatment of age-related bone loss
RA Lindtner, AN Tiaden, K Genelin, HL Ebner, C Manzl, M Klawitter, I Sitte, B Rechenberg, M Blauth, PJ Richards
Osteoporosis International 2013
Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism
MD Ruppe, SM de Beur
Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism 2013
Kieferosteonekrose unter antiosteoklastischer Therapie
IA Adamietz, M Kunkel
Der Onkologe 2013
The calcitonin and glucocorticoids combination: mechanistic insights into their class-effect synergy in experimental arthritis
A Al-Kashi, T Montero-Melendez, N Moradi-Bidhendi, JP Gilligan, N Mehta, M Perretti
PloS one 2013
Preosteocytes/osteocytes have the potential to dedifferentiate becoming a source of osteoblasts
E Torreggiani, BG Matthews, S Pejda, I Matic, MC Horowitz, D Grcevic, I Kalajzic
PloS one 2013
Can Zoledronic Acid be Beneficial for Promoting Tumor Response in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy?
A Charehbili, D Fontein, J Kroep, GJ Liefers, J Nortier, C Velde
Journal of Clinical Medicine 2013
Osteoclasts are not crucial for hematopoietic stem cell maintenance in adult mice
C Flores, I Moscatelli, CS Thudium, NS Gudmann, JS Thomsen, A Brüel, MA Karsdal, K Henriksen, J Richter
Haematologica 2013
Efficacy of pamidronate in children with low bone mineral density during and after chemotherapy for acute lymphoblastic leukemia and non-Hodgkin lymphoma
JM Lee, JE Kim, SH Bae, JO Hah
Blood Research 2013
Crosstalk between caveolin-1/extracellular signal-regulated kinase (ERK) and β-catenin survival pathways in osteocyte mechanotransduction
AR Gortazar, M Martin-Millan, B Bravo, LI Plotkin, T Bellido
The Journal of biological chemistry 2013
Absence of Cx43 selectively from osteocytes enhances responsiveness to mechanical force in mice
N Bivi, R Pacheco-Costa, LR Brun, TR Murphy, NR Farlow, AG Robling, T Bellido, LI Plotkin
Journal of Orthopaedic Research 2013
Differential impact of the Bisphosphonate Alendronate on undifferentiated and terminally differentiated human myogenic cells: Impact of Alendronate on human myogenic cell
K Shiomi, Y Nagata, T Kiyono, A Harada, N Hashimoto
Journal of Pharmacy and Pharmacology 2013
Ibandronate increases the expression of the pro-apoptotic gene FAS by epigenetic mechanisms in tumor cells
R Thaler, S Spitzer, H Karlic, C Berger, K Klaushofer, F Varga
Biochemical Pharmacology 2013
Sequential treatment with monofluorophosphate and zoledronic acid in osteoporotic rats
ML Brance, LR Brun, VE di Loreto, M Lupo, A Rigalli
Climacteric 2013
Bisphosphonates beyond their anti-osteoclastic properties
M Varenna
Rheumatology 2013
Painful prosthesis: approaching the patient with persistent pain following total hip and knee arthroplasty
P Piscitelli, G Iolascon, M Innocenti, R Civinini, A Rubinacci, M Muratore, M D'Arienzo, PT Leali, AM Carossino, ML Brandi
Clinical Cases in Mineral and Bone Metabolism 2013
Preosteocytes/Osteocytes Have the Potential to Dedifferentiate Becoming a Source of Osteoblasts
E Torreggiani, BG Matthews, S Pejda, I Matic, MC Horowitz, D Grcevic, I Kalajzic, S Gronthos
PloS one 2013
Crosstalk between Caveolin-1/Extracellular Signal-regulated Kinase (ERK) and β-Catenin Survival Pathways in Osteocyte Mechanotransduction*
AR Gortazar, M Martin-Millan, B Bravo, LI Plotkin, T Bellido
The Journal of biological chemistry 2013
The Osteocyte: An Endocrine Cell ... and More
Sarah L. Dallas, Matthew Prideaux, Lynda F. Bonewald
2013
The Osteocyte: An Endocrine Cell … and More
SL Dallas, M Prideaux, LF Bonewald
Endocrine reviews 2013
Bisphosphonates and Cancer: What Opportunities from Nanotechnology?
GD Rosa, G Misso, G Salzano, M Caraglia
Journal of drug delivery 2013
Feeding Blueberry Diets to Young Rats Dose-Dependently Inhibits Bone Resorption through Suppression of RANKL in Stromal Cells
J Zhang, OP Lazarenko, J Kang, ML Blackburn, MJ Ronis, TM Badger, JR Chen, XM Shi
PloS one 2013
The Calcitonin and Glucocorticoids Combination: Mechanistic Insights into Their Class–Effect Synergy in Experimental Arthritis
A Al-Kashi, T Montero-Melendez, N Moradi-Bidhendi, JP Gilligan, N Mehta, M Perretti, J Wallace
PloS one 2013
Osteoanabolic effect of alendronate and zoledronate on bone marrow stromal cells (BMSCs) isolated from aged female osteoporotic patients and its implications for their mode of action in the treatment of age-related bone loss
RA Lindtner, AN Tiaden, K Genelin, HL Ebner, C Manzl, M Klawitter, I Sitte, B von Rechenberg, M Blauth, PJ Richards
Osteoporosis International 2013
The osteoblast progenitor ERα stimulates Wnt signaling and bone accrual
Maria Almeida, Srividhya Iyer, Marta Martin-Millan, Shoshana M. Bartell, Li Han, Elena Ambrogini, Melda Onal, Jinhu Xiong, Robert Weinstein, Robert L. Jilka, Charles A. O'Brien, Stavros Manolagas
Journal of Clinical Investigation 2012
RSK2 protects mice against TNF-induced bone loss
C Böhm, A Derer, R Axmann, U Hillienhoff, MM Zaiss, J Luther, C Zech, M Stock, C Scholtysek, K Engelke, A Hess, JP Tuckermann, G Schett, JP David
Journal of cell science 2012
Bisphosphonates: effects on osteoblast
N Maruotti, A Corrado, A Neve, FP Cantatore
European Journal of Clinical Pharmacology 2012
In vitro and in vivo approaches to study osteocyte biology
I Kalajzic, BG Matthews, E Torreggiani, MA Harris, PD Pajevic, SE Harris
Bone 2012
Glucocorticoid-induced osteoporosis and osteonecrosis
RS Weinstein
Endocrinology and metabolism clinics of North America 2012
Is interaction between age-dependent decline in mechanical stimulation and osteocyte–estrogen receptor levels the culprit for postmenopausal-impaired bone formation?
R Sapir-Koren, G Livshits
Osteoporosis International 2012
The multiple facets of glucocorticoid action in rheumatoid arthritis
U Baschant, NE Lane, J Tuckermann
Nature Reviews Rheumatology 2012
Role of connexin 43 in the mechanism of action of alendronate: dissociation of anti-apoptotic and proliferative signaling pathways
V Lezcano, T Bellido, LI Plotkin, R Boland, S Morelli
Archives of Biochemistry and Biophysics 2012
Bisphosphonate Binding Affinity Affects Drug Distribution in Both Intracortical and Trabecular Bone of Rabbits
J Turek, FH Ebetino, MW Lundy, S Sun, BA Kashemirov, CE McKenna, MA Gallant, LI Plotkin, T Bellido, X Duan, JT Triffitt, RG Russell, DB Burr, MR Allen
Calcified Tissue International 2012
Cell autonomous requirement of connexin 43 for osteocyte survival: Consequences for endocortical resorption and periosteal bone formation
N Bivi, KW Condon, MR Allen, N Farlow, G Passeri, LR Brun, Y Rhee, T Bellido, LI Plotkin
Journal of Bone and Mineral Research 2012
Evolution of bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma and Waldenstrom's macroglobulinemia: a retrospective multicentric study
A Andriani, MT Petrucci, T Caravita, M Montanaro, N Villivà, A Levi, A Siniscalchi, V Bongarzoni, F Pisani, MD Muro, U Coppetelli, G Avvisati, A Zullo, A Agrillo, D Gaglioti
Blood Cancer Journal 2012
Deletion of Cx43 from Osteocytes Results in Defective Bone Material Properties but Does Not Decrease Extrinsic Strength in Cortical Bone
N Bivi, MT Nelson, ME Faillace, J Li, LM Miller, LI Plotkin
Calcified Tissue International 2012
Increased osteocyte death in multiple myeloma patients: role in myeloma-induced osteoclast formation
N Giuliani, M Ferretti, M Bolzoni, P Storti, M Lazzaretti, BD Palma, S Bonomini, E Martella, L Agnelli, A Neri, F Ceccarelli, C Palumbo
Leukemia 2012
The Epidemiology of Distal Radius Fractures
KW Nellans, E Kowalski, KC Chung
Hand Clinics 2012
Osteoconductive action of alendronate after implantation of beta tricalcium phosphate in rat adjuvant-induced arthritis
T Netsu, N Kondo, K Arai, A Ogose, N Endo
Journal of Bone and Mineral Metabolism 2012
The role of bone turnover markers in monitoring treatment in postmenopausal osteoporosis
P Szulc
Clinical Biochemistry 2012
Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo
AJ Roelofs, CA Stewart, S Sun, KM Błażewska, BA Kashemirov, CE McKenna, RG Russell, MJ Rogers, MW Lundy, FH Ebetino, FP Coxon
Journal of Bone and Mineral Research 2012
An aromatase polymorphism (g.132810C>T) predicts risk of bisphosphonate-related osteonecrosis of the jaw
FL Ferla, E Paolicchi, F Crea, S Cei, F Graziani, M Gabriele, R Danesi
Biomarkers in Medicine 2012
Pediatric Bone
M Bastepe, H Jüppner, RV Thakker
Pediatric Bone 2012
Comparison of Serum Dkk1 (Dickopff-1) and Bone Mineral Density in Patients on Bisphosphonate Treatment Vs no Treatment
AR Memon, JS Butler, MV O'Riordan, E Guerin, BD Dimitrov, JA Harty
Journal of Clinical Densitometry 2012
Effectiveness of pamidronate as treatment of symptomatic osteonecrosis occurring in children treated for acute lymphoblastic leukemia
C Leblicq, C Laverdière, JC Décarie, JF Delisle, MH Isler, A Moghrabi, G Chabot, N Alos
Pediatric Blood & Cancer 2012
Connexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading
SA Lloyd, GS Lewis, Y Zhang, EM Paul, HJ Donahue
Journal of Bone and Mineral Research 2012
Prevention of aortic valve stenosis: A realistic therapeutic target?
DT Ngo, AL Sverdlov, JD Horowitz
Pharmacology & Therapeutics 2012
No Reduction in Circulating Preosteoclasts 18 Months after Treatment with Zoledronate: Analysis from a Randomized Placebo Controlled Trial
N Dalbeth, B Pool, A Stewart, A Horne, ME House, J Cornish, IR Reid
Calcified Tissue International 2012
Concentration-dependent effects of tiludronate on equine articular cartilage explants incubated with and without interleukin-1β
KF Duesterdieck-Zellmer, N Driscoll, JF Ott
American Journal of Veterinary Research 2012
Gap junction and hemichannel functions in osteocytes
AE Loiselle, JX Jiang, HJ Donahue
Bone 2012
There are many potential medical therapies for atraumatic osteonecrosis
J Fessel
Rheumatology 2012
Clinical role of bisphosphonate therapy
G Hampson, I Fogelman
International journal of women's health 2012
Skeletal muscle secreted factors prevent glucocorticoid-induced osteocyte apoptosis through activation of β-catenin
K Jähn, N Lara-Castillo, L Brotto, CL Mo, ML Johnson, M Brotto, LF Bonewald
European cells & materials 2012
SKELETAL MUSCLE SECRETED FACTORS PREVENT GLUCOCORTICOID-INDUCED OSTEOCYTE APOPTOSIS THROUGH ACTIVATION OF B-CATENIN
K Jähn, N Lara-Castillo, L Brotto, CL Mo, ML Johnson, M Brotto, LF Bonewald
European cells & materials 2012
Low-dose Risedronate Sodium Protects Bone Cells after Abrupt Oestrogen Withdrawal
G Wang, Z Zhu, C Lei, M Li, F Liu, Y Mao, Z Yu, M Liu, X Zhao, T Tang
J INT MED RES 2012
Simulated resistance training, but not alendronate, increases cortical bone formation and suppresses sclerostin during disuse
BR Macias, JM Swift, MI Nilsson, HA Hogan, SD Bouse, SA Bloomfield
Journal of applied physiology 2012
Connexin43 interacts with βarrestin: a pre-requisite for osteoblast survival induced by parathyroid hormone
N Bivi, V Lezcano, M Romanello, T Bellido, LI Plotkin
Journal of Cellular Biochemistry 2011
Glucocorticoid-induced osteonecrosis
RS Weinstein
Endocrine 2011
Osteoprotegerin Prevents Glucocorticoid-Induced Osteocyte Apoptosis in Mice
RS Weinstein, CA O'Brien, M Almeida, H Zhao, PK Roberson, RL Jilka, SC Manolagas
Endocrinology 2011
Glucocorticoid dose determines osteocyte cell fate
J Jia, W Yao, M Guan, W Dai, M Shahnazari, R Kar, L Bonewald, JX Jiang, NE Lane
The FASEB Journal 2011
A bisphosphonate that does not affect osteoclasts prevents osteoblast and osteocyte apoptosis and the loss of bone strength induced by glucocorticoids in mice
LI Plotkin, N Bivi, T Bellido
Bone 2011
Novel actions of bisphosphonates in bone: Preservation of osteoblast and osteocyte viability
T Bellido, LI Plotkin
Bone 2011
LIS1 Regulates Osteoclast Formation and Function through Its Interactions with Dynein/Dynactin and Plekhm1
S Ye, TW Fowler, NJ Pavlos, PY Ng, K Liang, Y Feng, M Zheng, R Kurten, SC Manolagas, H Zhao
PloS one 2011
Bisphosphonates: The first 40years
RG Russell
Bone 2011
Denosumab and bisphosphonates: Different mechanisms of action and effects
R Baron, S Ferrari, RG Russell
Bone 2011
The effects of bisphosphonates on jaw bone remodeling, tissue properties, and extraction healing
MR Allen
Odontology 2011
Effect of Bisphosphonates on the Progression of Degenerative Aortic Stenosis
AL Innasimuthu, WE Katz
Echocardiography 2011
Bisphosphonates, specific inhibitors of osteoclast function and a class of drugs for osteoporosis therapy
B Li, JF Chau, X Wang, WF Leong
Journal of Cellular Biochemistry 2011
Bisphosphonate effects on bone turnover, microdamage, and mechanical properties: What we think we know and what we know that we don't know
MR Allen, DB Burr
Bone 2011
Glucocorticoid-Induced Bone Disease
RS Weinstein
New England Journal of Medicine 2011
Bone-bound bisphosphonate inhibits growth of adjacent non-bone cells
J Cornish, U Bava, KE Callon, J Bai, D Naot, IR Reid
Bone 2011
Bisphosphonates in phenytoin-induced bone disorder
S Khanna, KK Pillai, D Vohora
Bone 2011
Protein phosphatases: Possible bisphosphonate binding sites mediating stimulation of osteoblast proliferation
S Morelli, PS Bilbao, S Katz, V Lezcano, E Roldán, R Boland, G Santillan
Archives of Biochemistry and Biophysics 2011
Dose-dependent differential effects of risedronate on gene expression in osteoblasts
J Wang, PH Stern
Biochemical Pharmacology 2011
Protein isoprenylation regulates osteogenic differentiation of mesenchymal stem cells: effect of alendronate, and farnesyl and geranylgeranyl transferase inhibitors
G Duque, C Vidal, D Rivas
British Journal of Pharmacology 2011
International Review of Cell and Molecular Biology
A Chavez, M Smith, D Mehta
International Review of Cell and Molecular Biology Volume 290 2011
Physiology of the aging bone and mechanisms of action of bisphosphonates
LJ Dominguez, G Bella, M Belvedere, M Barbagallo
Biogerontology 2011
Ibandronate promotes osteogenic differentiation of periodontal ligament stem cells by regulating the expression of microRNAs
Q Zhou, ZN Zhao, JT Cheng, B Zhang, J Xu, F Huang, RN Zhao, YJ Chen
Biochemical and Biophysical Research Communications 2011
Shotgun proteomics analysis reveals new unsuspected molecular effectors of nitrogen-containing bisphosphonates in osteocytes
N Bivi, P Picotti, LN Müller, M Romanello, L Moro, F Quadrifoglio, G Tell
Journal of Proteomics 2011
Densitometric Threshold and Vertebral Fractures in Heart Transplant Patients
LD Carbonare, M Zanatta, V Braga, S Sella, MT Vilei, G Feltrin, A Gambino, I Pepe, M Rossini, S Adami, S Giannini
Transplantation 2011
Bisphosphonates in orthopedic applications
JM Wilkinson, DG Little
Bone 2011
Cancellous bone formation response to simulated resistance training during disuse is blunted by concurrent alendronate treatment
JM Swift, SN Swift, MI Nilsson, HA Hogan, SD Bouse, SA Bloomfield
Journal of Bone and Mineral Research 2011
Alendronate and raloxifene affect the osteoprotegerin/RANKL system in human osteoblast primary cultures from patients with osteoporosis and osteoarthritis
M Giner, MJ Rios, MJ Montoya, MA Vázquez, C Miranda, R Pérez-Cano
European Journal of Pharmacology 2011
Low concentrations of alendronate increase the local invasive potential of osteoblastic sarcoma cell lines via connexin 43 activation
K Yoshitani, A Kido, K Honoki, M Akahane, H Fujii, Y Tanaka
Pathology - Research and Practice 2011
Pathophysiology of atypical femoral fractures and osteonecrosis of the jaw
J Compston
Osteoporosis International 2011
Up-regulation of inhibitors of DNA binding/differentiation gene during alendronate-induced osteoblast differentiation
AR Kang, YR Oh, HY Kim, MJ Park, BS Joo, WJ Choi, JY Lee, MH Jung, YI Ji, JS Choi
Archives of Gynecology and Obstetrics 2011
Diagnosis and management of extensive vascular malformations of the lower limb
P Redondo, L Aguado, A Martínez-Cuesta
Journal of the American Academy of Dermatology 2011
Small interfering RNA knocks down the molecular target of alendronate, farnesyl pyrophosphate synthase, in osteoclast and osteoblast cultures
Y Wang, A Panasiuk, DW Grainger
Molecular Pharmaceutics 2011
The Role of Bisphosphonates in Multiple Myeloma: Mechanisms, Side Effects, and the Future
S Pozzi, N Raje
The oncologist 2011
Overexpression of Bcl2 in Osteoblasts Inhibits Osteoblast Differentiation and Induces Osteocyte Apoptosis
T Moriishi, Z Maruyama, R Fukuyama, M Ito, T Miyazaki, H Kitaura, H Ohnishi, T Furuichi, Y Kawai, R Masuyama, H Komori, K Takada, H Kawaguchi, T Komori
PloS one 2011
Bisphosphonate stimulation of osteoblasts and osteoblastic metastasis as a mechanism of hypocalcaemia
JW Ho
Medical Hypotheses 2011
Pathogenesis of aortic stenosis: not just a matter of wear and tear
AL Sverdlov, DT Ngo, MJ Chapman, OA Ali, YY Chirkov, JD Horowitz
American Journal of Cardiovascular Disease 2011
CONNEXIN 43 AND BONE: NOT JUST A GAP JUNCTION PROTEIN
LI Plotkin
Actualizaciones en osteologia 2011
Ostéoporose cortisonique
C Marcelli
EMC - Appareil locomoteur 2011
Effects of risedronate on cortical and trabecular bone of the mandible in glucocorticoid-treated growing rats
Y Fujita, K Watanabe, S Uchikanbori, K Maki
American Journal of Orthodontics and Dentofacial Orthopedics 2011
A systematic review of microsurgical reconstruction of the jaws using vascularized fibula flap technique in patients with bisphosphonate-related osteonecrosis
Roberto Sacco, Gianluca Sacco, Alessandro Acocella, Silvana Sale, Nicola Sacco, Edoardo Baldoni
Journal of applied oral science : revista FOB 2011
FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice
E Ambrogini, M Almeida, M Martin-Millan, JH Paik, RA Depinho, L Han, J Goellner, RS Weinstein, RL Jilka, CA O'Brien, SC Manolagas
Cell Metabolism 2010
Glucocorticoid-Induced Autophagy in Osteocytes
X Xia, R Kar, J Gluhak-Heinrich, W Yao, NE Lane, LF Bonewald, SK Biswas, WK Lo, JX Jiang
Journal of Bone and Mineral Research 2010
The Estrogen Receptor-α in Osteoclasts Mediates the Protective Effects of Estrogens on Cancellous But Not Cortical Bone
M Martin-Millan, M Almeida, E Ambrogini, L Han, H Zhao, RS Weinstein, RL Jilka, CA O'Brien, SC Manolagas
Molecular Endocrinology 2010
Intermittent parathyroid hormone administration counteracts the adverse effects of glucocorticoids on osteoblast and osteocyte viability, bone formation, and strength in mice
RS Weinstein, RL Jilka, M Almeida, PK Roberson, SC Manolagas
Endocrinology 2010
Osteocyte apoptosis and control of bone resorption following ovariectomy in mice
KB Emerton, B Hu, AA Woo, A Sinofsky, C Hernandez, RJ Majeska, KJ Jepsen, MB Schaffler
Bone 2010
Oxidative Stress Stimulates Apoptosis and Activates NF-κB in Osteoblastic Cells via a PKCβ/p66shc Signaling Cascade: Counter Regulation by Estrogens or Androgens
M Almeida, L Han, E Ambrogini, SM Bartell, SC Manolagas
Molecular Endocrinology 2010
Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo
AJ Roelofs, FP Coxon, FH Ebetino, MW Lundy, ZJ Henneman, GH Nancollas, S Sun, KM Blazewska, JL Bala, BA Kashemirov, AB Khalid, CE McKenna, MJ Rogers
Journal of Bone and Mineral Research 2010
Osteocyte: the unrecognized side of bone tissue
GY Rochefort, S Pallu, CL Benhamou
Osteoporosis International 2010
The effect of risedronate on osteogenic lineage is mediated by cyclooxygenase-2 gene upregulation
MT Valenti, S Giannini, L Donatelli, M Zanatta, F Bertoldo, S Sella, MT Vilei, E Ossi, G Realdi, VL Cascio, LD Carbonare
Arthritis Research & Therapy 2010
RANKL Inhibition Improves Bone Properties in a Mouse Model of Osteogenesis Imperfecta
R Bargman, A Huang, AL Boskey, C Raggio, N Pleshko
Connective Tissue Research 2010
Near-infrared fluorescent probe traces bisphosphonate delivery and retention in vivo
KM Kozloff, LI Volakis, JC Marini, MS Caird
Journal of Bone and Mineral Research 2010
Estrogen and glucocorticoid regulate osteoblast differentiation through the interaction of bone morphogenetic protein-2 and tumor necrosis factor-α in C2C12 cells
Y Matsumoto, F Otsuka, M Takano, T Mukai, R Yamanaka, M Takeda, T Miyoshi, K Inagaki, K Sada, H Makino
Molecular and Cellular Endocrinology 2010
Calcitonin impairs the anabolic effect of PTH in young rats and stimulates expression of sclerostin by osteocytes
JH Gooi, S Pompolo, MA Karsdal, NH Kulkarni, I Kalajzic, SH McAhren, B Han, JE Onyia, PW Ho, MT Gillespie, NC Walsh, LY Chia, JM Quinn, TJ Martin, NA Sims
Bone 2010
Safety and tolerability of zoledronic acid and other bisphosphonates in osteoporosis management
LD Carbonare, M Zanatta, A Gasparetto, MT Valenti
Drug, healthcare and patient safety 2010
Inhibition of the progesterone nuclear receptor during the bone linear growth phase increases peak bone mass in female mice
W Yao, W Dai, M Shahnazari, A Pham, Z Chen, H Chen, M Guan, NE Lane
PloS one 2010
The effect of zoledronate during bone healing
MA Matos, U Tannuri, R Guarniero
Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 2010
Management of glucocorticoid-induced osteoporosis: prevalence, and emerging treatment options
J Payer, K Brazdilova, P Jackuliak
Drug, healthcare and patient safety 2010
Inhibition of osteoclast function reduces hematopoietic stem cell numbers in vivo
S Lymperi, A Ersek, F Ferraro, F Dazzi, NJ Horwood
Blood 2010
Gap Junctions and Biophysical Regulation of Bone Cells
SA Lloyd, HJ Donahue
Clinical Reviews in Bone and Mineral Metabolism 2010
Effect of Risedronate on Osteocyte Viability and Bone Turnover in Paired Iliac Bone Biopsies from Early Postmenopausal Women
S Qiu, RJ Phipps, FH Ebetino, S Palnitkar, DS Rao
Calcified Tissue International 2010
Effects of Vitamin K2 on Cortical and Cancellous Bone Mass, Cortical Osteocyte and Lacunar System, and Porosity in Sciatic Neurectomized Rats
J Iwamoto, H Matsumoto, T Takeda, Y Sato, JK Yeh
Calcified Tissue International 2010
Osteonecrosis of the Jaw and the Role of Macrophages
M Pazianas
JNCI Journal of the National Cancer Institute 2010
Are All Bisphosphonates the Same? Potential Reasons for Clinical Differences: A Perspective
JA Simon
Journal of Women's Health 2010
Bisphosphonate protonation states, conformations, and dynamics on bone mineral probed by solid-state NMR without isotope enrichment
MS Ironside, MJ Duer, DG Reid, S Byard
European Journal of Pharmaceutics and Biopharmaceutics 2010
2009 Santa Fe Bone Symposium
EM Lewiecki, JP Bilezikian, AJ Laster, PD Miller, RR Recker, RG Russell, MP Whyte
Journal of Clinical Densitometry 2010
A Sustained Release of Lovastatin from Biodegradable, Elastomeric Polyurethane Scaffolds for Enhanced Bone Regeneration
T Yoshii, AE Hafeman, JS Nyman, JM Esparza, K Shinomiya, DM Spengler, GR Mundy, GE Gutierrez, SA Guelcher
Tissue Engineering Part A 2010
Effects of estrogen deficiency and bisphosphonate therapy on osteocyte viability and microdamage accumulation in an ovine model of osteoporosis
O Brennan, OD Kennedy, TC Lee, SM Rackard, FJ O'Brien
Journal of Orthopaedic Research 2010
Pamidronate, farnesyl transferase, and geranylgeranyl transferase-I inhibitors affects cell proliferation, apoptosis, and OPG/RANKL mRNA expression in stromal cells of giant cell tumor of bone
CP Lau, L Huang, SK Tsui, PK Ng, PY Leung, SM Kumta
Journal of Orthopaedic Research 2010
Mechanical Induction of PGE2 in Osteocytes Blocks Glucocorticoid-Induced Apoptosis Through Both the β-Catenin and PKA Pathways
Y Kitase, L Barragan, H Qing, S Kondoh, JX Jiang, ML Johnson, LF Bonewald
Journal of Bone and Mineral Research 2010
Effects of clodronate combined with hydroxyapatite on multi-directional differentiation of mesenchymal stromal cells
X Liu, C Bao, J Hu, G Yin, E Luo
Archives of Medical Science : AMS 2010
Effect of Alendronate on Pseudomembrane Cytokine Expression in Patients with Aseptic Osteolysis
G Holt, J Reilly, RM Meek
The Journal of Arthroplasty 2010
Validity of prevention of glucocorticoid-induced alveolar bone loss in rat by either calcitonin or alendronate administration
BA Ezzat
Archives of Oral Biology 2010
The Molecular Biology of Sex Steroids in Bone
S Kousteni
Osteoporosis in Men 2010
Vitamins & Hormones
KJ Hare, FK Knop
Vitamins & Hormones 2010
Osteogenic Activity of Locally Applied Small Molecule Drugs in a Rat Femur Defect Model
JA Cottrell, FM Vales, D Schachter, S Wadsworth, R Gundlapalli, R Kapadia, JP O'Connor
Journal of Biomedicine and Biotechnology 2010
Inhibition of the Progesterone Nuclear Receptor during the Bone Linear Growth Phase Increases Peak Bone Mass in Female Mice
W Yao, W Dai, M Shahnazari, A Pham, Z Chen, H Chen, M Guan, NE Lane, JA Calbet
PloS one 2010
Bisphosphonates in the treatment of metabolic bone diseases
HP Arantes, AG da Silva, M Lazaretti-Castro
Arquivos brasileiros de endocrinologia e metabologia 2010
EFFECTS OF PHYSICAL EXERCISE ON FEMORAL BONE MINERAL DENSITY AND OSTEOCYTE MICROMORPHOLOGY IN YOUNG OVARIECTOMIZED (OVX) RATS
T Kawakami, S Takise, H Kawata
Japanese Journal of Physical Fitness and Sports Medicine 2010
The effect of the alendronate on OPG/RANKL system in differentiated primary human osteoblasts
A Enjuanes, S Ruiz-Gaspà, P Peris, D Ozalla, L Álvarez, A Combalia, MJ de Osaba, A Monegal, A Pares, N Guañabens
Endocrine 2010
Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice
RS Weinstein, C Wan, Q Liu, Y Wang, M Almeida, CA O'Brien, J Thostenson, PK Roberson, AL Boskey, TL Clemens, SC Manolagas
Aging Cell 2009
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha
M Almeida, M Martin-Millan, E Ambrogini, RB 3rd, L Han, XD Chen, PK Roberson, RS Weinstein, CA O'Brien, RL Jilka, SC Manolagas
Journal of Bone and Mineral Research 2009
Effects of the bisphosphonate risedronate on osteopenia in OASIS-deficient mice
H Sekiya, T Murakami, A Saito, S Hino, K Tsumagari, K Ochiai, K Imaizumi
Journal of Bone and Mineral Metabolism 2009
Transcriptome and Proteome Analysis of Osteocytes Treated with Nitrogen-Containing Bisphosphonates
N Bivi, JZ Bereszczak, M Romanello, LA Zeef, D Delneri, F Quadrifoglio, L Moro, FL Brancia, G Tell
Journal of Proteome Research 2009
Modulation of murine bone marrow-derived CFU-F and CFU-OB byin vivobisphosphonate and fluoride treatments
MY Chou, D Yan, T Jafarov, ET Everett
Orthodontics & Craniofacial Research 2009
Bisphosphonates and BMU birth rate: response to comments by Ott
E Seeman
Osteoporosis International 2009
Mandibular necrosis in beagle dogs treated with bisphosphonates
DB Burr, MR Allen
Orthodontics & Craniofacial Research 2009
In vivo Performance of Osteoactivated Cellulose-Based Scaffolds in Bony Critical-Size Defects
S Ponader, H Brandt, E Vairaktaris, C Wilmowsky, W Göthel, R Lutz, KA Schlegel, FW Neukam, P Greil, FA Müller, E Nkenke
Advanced Engineering Materials 2009
The effect of the alendronate on OPG/RANKL system in differentiated primary human osteoblasts
A Enjuanes, S Ruiz-Gaspà, P Peris, D Ozalla, L Álvarez, A Combalia, MJ de Osaba, A Monegal, A Pares, N Guañabens
Endocrine 2009
Suppressive effect of dexamethasone on TIMP-1 production involves murine osteoblastic MC3T3-E1 cell apoptosis
H Xie, LL Tang, XH Luo, XY Wu, XP Wu, HD Zhou, LQ Yuan, EY Liao
Amino Acids 2009
Importance of microcracks in etiology of bisphosphonate-related osteonecrosis of the jaw: a possible pathogenetic model of symptomatic and non-symptomatic osteonecrosis of the jaw based on scanning electron microscopy findings
S Hoefert, I Schmitz, A Tannapfel, H Eufinger
Clinical Oral Investigations 2009
Timing, rather than the concentration of cyclic AMP, correlates to osteogenic differentiation of human mesenchymal stem cells
R Siddappa, J Doorn, J Liu, E Langerwerf, R Arends, C Blitterswijk, J Boer
Journal of Tissue Engineering and Regenerative Medicine 2009
Why to Keep Osteocytes Alive and How?
T Bellido
Journal of Korean Endocrine Society 2009
Alendronate augments interleukin-1β release from macrophages infected with periodontal pathogenic bacteria through activation of caspase-1
X Deng, R Tamai, Y Endo, Y Kiyoura
Toxicology and Applied Pharmacology 2009
Effects of Bisphosphonate on Bone Metabolism of Growing Rat Tibia in Glucocorticoid-Induced Osteoporosis
K Hasegawa, K Maki
The Journal of the Kyushu Dental Society 2009
Incidence of bisphosphonate-associated osteonecrosis of the jaws in breast cancer patients
C Walter, B Al-Nawas, A Bois, L Buch, P Harter, KA Grötz
Cancer 2009
In vitrokinetic study of growth and mineralization of osteoblast-like cells (Saos-2) on titanium surface coated with a RGD functionalized bisphosphonate
J Beuvelot, D Portet, G Lecollinet, MF Moreau, MF Baslé, D Chappard, H Libouban
Journal of Biomedical Materials Research Part B: Applied Biomaterials 2009
Alendronate Improves Low Bone Mineral Density Induced by Steroid Therapy in Crohn's Disease
T Tsujikawa, A Andoh, O Inatomi, S Bamba, T Nakahara, M Sasaki, H Saito, Y Fujiyama
Internal Medicine 2009
Glucocorticoid-induced osteoporosis: hope on the HORIZON
L Gennari, JP Bilezikian
The Lancet 2009
The Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaw: So Many Hypotheses, So Few Data
MR Allen, DB Burr
Journal of Oral and Maxillofacial Surgery 2009
Alternative Indications for Bisphosphonate Therapy
R Landesberg, S Eisig, I Fennoy, E Siris
Journal of Oral and Maxillofacial Surgery 2009
Hipercalcemia del adulto
MH Vieillard, I Gerot-Legroux, B Cortet
EMC - Aparato Locomotor 2009
Hypercalcémie de l'adulte
MH Vieillard, I Gerot-Legroux, B Cortet
EMC - Appareil locomoteur 2009
Weekly clodronate treatment prevents bone loss and vertebral fractures in women with subclinical Cushing’s syndrome
L Tauchmanova, E Guerra, R Pivonello, MC Martino, M Leo, F Caggiano, G Lombardi, A Colao
Journal of Endocrinological Investigation 2009
The Antiresorptive Effects of a Single Dose of Zoledronate Persist for Two Years: A Randomized, Placebo-Controlled Trial in Osteopenic Postmenopausal Women
A Grey, MJ Bolland, D Wattie, A Horne, G Gamble, IR Reid
The Journal of clinical endocrinology and metabolism 2009
Weekly clodronate treatment prevents bone loss and vertebral fractures in women with subclinical Cushing’s syndrome
L Tauchmanova, E Guerra, R Pivonello, MC Martino, MD Leo, F Caggiano, G Lombardi, A Colao
Journal of Endocrinological Investigation 2009
Osteoporosis
JJ Westendorf
Osteoporosis International 2008
Osteoporosis
JJ Westendorf
Osteoporosis International 2008
Osteoporosis
JJ Westendorf
Osteoporosis International 2008
Osteoporosis
JJ Westendorf
Osteoporosis International 2008
Osteoporosis
JJ Westendorf
Osteoporosis International 2008
Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents
T Yamaza, Y Miura, Y Bi, Y Liu, K Akiyama, W Sonoyama, V Patel, S Gutkind, M Young, S Gronthos, A Le, CY Wang, WJ Chen, S Shi
PloS one 2008
Risk Factors, Prevention, and Treatment of Corticosteroid-Induced Osteoporosis in Adults
KM Ruf, NK Johnson, T Clifford, KM Smith
Orthopedics 2008
Alendronate Enhances Osteogenic Differentiation of Bone Marrow Stromal Cells: A Preliminary Study
HK Kim, JH Kim, AA Abbas, TR Yoon
Clinical Orthopaedics and Related Research® 2008
Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy
RG Russell, NB Watts, FH Ebetino, MJ Rogers
Osteoporosis International 2008
The Effects of Systemic Alendronate With or Without Intraalveolar Collagen Sponges on Postextractive Bone Resorption
F Graziani, S Rosini, S Cei, FL Ferla, M Gabriele
Journal of Craniofacial Surgery 2008
Aminobisphosphonates Cause Osteoblast Apoptosis and Inhibit Bone Nodule Formation In Vitro
AI Idris, J Rojas, IR Greig, RJ Hof, SH Ralston
Calcified Tissue International 2008
Bisphosphonates: how do they work?
SE Papapoulos
Best Practice & Research Clinical Endocrinology & Metabolism 2008
Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo
LI Plotkin, V Lezcano, J Thostenson, RS Weinstein, SC Manolagas, T Bellido
Journal of Bone and Mineral Research 2008
Regulation of bim in glucocorticoid-mediated osteoblast apoptosis
B Espina, M Liang, RG Russell, PA Hulley
Journal of Cellular Physiology 2008
Enhancement of periprosthetic bone quality with topical hydroxyapatite-bisphosphonate composite
SJ Suratwala, SK Cho, JJ van Raalte, SH Park, SW Seo, SS Chang, TR Gardner, FY Lee
The Journal of bone and joint surgery. American volume 2008
Mandible matrix necrosis in beagle dogs after 3 years of daily oral bisphosphonate treatment
MR Allen, DB Burr
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2008
Bisphosphonates: mechanism of action and role in clinical practice
MT Drake, BL Clarke, S Khosla
Mayo Clinic proceedings. Mayo Clinic 2008
Calcitonin Promotes Outgrowth of Trophoblast Cells on Endometrial Epithelial Cells: Involvement of Calcium Mobilization and Protein Kinase C Activation
HY Li, JT Shen, SP Chang, WL Hsu, YJ Sung
Placenta 2008
In vitro response of hFOB cells to pamidronate modified sodium silicate coated cellulose scaffolds
S Ponader, H Brandt, E Vairaktaris, C Wilmowsky, E Nkenke, KA Schlegel, FW Neukam, S Holst, FA Müller, P Greil
Colloids and Surfaces B: Biointerfaces 2008
Prevention of strain-related osteopenia in aseptic loosening of hip prostheses using perioperative bisphosphonate
AE Goodship, GW Blunn, J Green, MJ Coathup
Journal of Orthopaedic Research 2008
Connexin43 Modulation of Osteoblast/Osteocyte Apoptosis: A Potential Therapeutic Target?
R Civitelli
Journal of Bone and Mineral Research 2008
Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control study
BA Lenart, AS Neviaser, S Lyman, CC Chang, F Edobor-Osula, B Steele, MC Meulen, DG Lorich, JM Lane
Osteoporosis International 2008
Beneficial Effects of Combined Administration of Alendronate and Alfacalcidol on Cancellous Bone Mass of the Tibia in Orchidectomized Rats: A Bone Histomorphometry Study
J IWAMOTO, T TAKEDA, H MATSUMOTO, Y SATO, JK YEH
Journal of Nutritional Science and Vitaminology 2008
Bisphosphonatassoziierte Nekrosen der Kiefer
D Hermes, P Beier, K Peters
Der Onkologe 2008
Effects of Vitamin K2 and Risedronate on Bone Formation and Resorption, Osteocyte Lacunar System, and Porosity in the Cortical Bone of Glucocorticoid-Treated Rats
J Iwamoto, H Matsumoto, T Takeda, Y Sato, X Liu, JK Yeh
Calcified Tissue International 2008
Radiologic and Serologic Features of Extensive Venous Malformations Associated with Atrophy, Osteoporosis, and Visceral Involvement: Implications for Future Management
P Redondo, G Bastarrika
Dermatologic Surgery 2008
Optimum management of glucocorticoid-treated patients
S Trikudanathan, GT McMahon
Nature Clinical Practice Endocrinology & Metabolism 2008
Stimulation of osteogenic differentiation and inhibition of adipogenic differentiation in bone marrow stromal cells by alendronate via ERK and JNK activation
L Fu, T Tang, Y Miao, S Zhang, Z Qu, K Dai
Bone 2008
Calculating clinically relevant drug doses to use in animal studies
RK Fuchs, MR Allen, KW Condon, S Reinwald, LM Miller, D McClenathan, B Keck, RJ Phipps, DB Burr
Osteoporosis International 2008
Differential Response of Risedronate on Tibial and Mandibular Bone Quality in Glucocorticoid-treated Growing Rats
Y Fujita
The Journal of the Kyushu Dental Society 2008
Effect of progesterone on apoptosis of murine MC3T3-E1 osteoblastic cells
QP Wang, H Xie, LQ Yuan, XH Luo, H Li, D Wang, P Meng, EY Liao
Amino Acids 2008
Stainless steel screws coated with bisphosphonates gave stronger fixation and more surrounding bone. Histomorphometry in rats
K Wermelin, F Suska, P Tengvall, P Thomsen, P Aspenberg
Bone 2008
Opposing effects of bisphosphonates and advanced glycation end-products on osteoblastic cells
MV Gangoiti, AM Cortizo, V Arnol, JI Felice, AD McCarthy
European Journal of Pharmacology 2008
Effects of alendronate and pamidronate on cultured rat metatarsal bones: Failure to prevent dexamethasone-induced growth retardation
TJ Heino, AS Chagin, M Takigawa, L Sävendahl
Bone 2008
Histomorphometric Evaluation of the Effects of Zoledronic Acid on Mandibular Distraction Osteogenesis in Rabbits
AA Pampu, D Dolanmaz, HH Tüz, MC Avunduk, RŞ Kisşnisşci
Journal of Oral and Maxillofacial Surgery 2008
Zoledronic acid – does it have anabolic as well as anti-resorptive effects?
JE Compston
IBMS BoneKEy 2008
An update on the pharmacology of bisphosphonates and analogues with lower bone affinity
FP Coxon
IBMS BoneKEy 2008
Bisphosphonates: Mechanism of Action and Role in Clinical Practice
MT Drake, BL Clarke, S Khosla
Mayo Clinic Proceedings 2008
Principles of Bone Biology
CJ Rosen, T Niu
Principles of Bone Biology 2008
Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells
FP Coxon, K Thompson, AJ Roelofs, FH Ebetino, MJ Rogers
Bone 2008
Treatment of Renal Transplant Recipients With Low Bone Mineral Density: A Randomized Prospective Trial of Alendronate, Alfacalcidol, and Alendronate Combined With Alfacalcidol
S Trabulus, MR Altiparmak, S Apaydin, K Serdengecti, M Sariyar
Transplantation Proceedings 2008
Pharmacologic Stem Cell Based Intervention as a New Approach to Osteoporosis Treatment in Rodents
T Yamaza, Y Miura, Y Bi, Y Liu, K Akiyama, W Sonoyama, V Patel, S Gutkind, M Young, S Gronthos, A Le, CY Wang, WJ Chen, S Shi, T Zwaka
PloS one 2008
Enhancement of Periprosthetic Bone Quality with Topical Hydroxyapatite-Bisphosphonate Composite:
SJ Suratwala, SK Cho, JJ van Raalte, SH Park, SW Seo, SS Chang, TR Gardner, FY Lee
The Journal of Bone and Joint Surgery. American volume. 2008
Parathyroid hormone mediates bone growth through the regulation of osteoblast proliferation and differentiation
GJ Pettway, JA Meganck, AJ Koh, ET Keller, SA Goldstein, LK McCauley
Bone 2007
Receptor Activator of Nuclear Factor κB Ligand and Osteoprotegerin Regulation of Bone Remodeling in Health and Disease
AE Kearns, S Khosla, PJ Kostenuik
Endocrine reviews 2007
Salmon calcitonin: a review of current and future therapeutic indications
CH Chesnut, M Azria, S Silverman, M Engelhardt, M Olson, L Mindeholm
Osteoporosis International 2007
The aminobisphosphonate risedronate preserves localized mineral and material properties of bone in the presence of glucocorticoids
G Balooch, W Yao, JW Ager, M Balooch, RK Nalla, AE Porter, RO Ritchie, NE Lane
Arthritis & Rheumatism 2007
Effect of raloxifene treatment on osteocyte apoptosis in postmenopausal women
HW van Essen, PJ Holzmann, MA Blankenstein, P Lips, N Bravenboer
Calcified Tissue International 2007
Calcitonin and prednisolone display antagonistic actions on bone and have synergistic effects in experimental arthritis
L Mancini, MJ Paul-Clark, G Rosignoli, R Hannon, JE Martin, I Macintyre, M Perretti
The American Journal of Pathology 2007
Signaling and transcriptional regulation in osteoblast commitment and differentiation
Huang W, Yang S, Shao J, Li YP
Frontiers in bioscience : a journal and virtual library 2007
Effects of antifracture drugs in postmenopausal, male and glucocorticoid-induced osteoporosis – usefulness of alendronate and risedronate
J Iwamoto, T Takeda, Y Sato
Expert Opinion on Pharmacotherapy 2007
The Molecular Mechanisms of Action of Bisphosphonates
K Thompson, MJ Rogers
Clinical Reviews in Bone and Mineral Metabolism 2007
Anabolic effects of bisphosphonates on peri-implant bone stock
F Knoch, C Eckhardt, CI Alabre, E Schneider, HE Rubash, AS Shanbhag
Biomaterials 2007
Alendronate Has an Anabolic Effect on Bone Through the Differentiation of Mesenchymal Stem Cells
G Duque, D Rivas
Journal of Bone and Mineral Research 2007
Addition of bisphosphonate to antibiotic and anti-inflammatory treatment reduces bone resorption in experimentalStaphylococcus aureus-induced arthritis
M Verdrengh, H Carlsten, C Ohlsson, A Tarkowski
Journal of Orthopaedic Research 2007
Vanadate prevents glucocorticoid-induced apoptosis of osteoblasts in vitro and osteocytes in vivo
MM Conradie, H Wet, DD Kotze, JM Burrin, FS Hough, PA Hulley
The Journal of endocrinology 2007
Alendronate inhibits PTH (1-34)-induced bone morphogenetic protein expression in MC3T3-E1 preosteoblastic cells
PS Issack, MH Lauerman, DL Helfet, SB Doty, JM Lane
HSS journal : the musculoskeletal journal of Hospital for Special Surgery 2007
Alendronate increases BMD at appendicular and axial skeletons in patients with established osteoporosis
L Qin, W Choy, S Au, M Fan, P Leung
Journal of orthopaedic surgery and research 2007
Einfluss der Bisphosphonate auf die Frakturheilung
C Seebach, A Kurth, I Marzi
Der Orthopäde 2007
Successful treatment of avascular bone necrosis of the knee with neridronate: a case report
A Corrado, L Quarta, S Errico, FP Cantatore
Rheumatology International 2007
Perspective: Quantifying Osteoblast and Osteocyte Apoptosis: Challenges and Rewards
RL Jilka, RS Weinstein, AM Parfitt, SC Manolagas
Journal of Bone and Mineral Research 2007
Drug Insight: the use of bisphosphonates for the prevention and treatment of osteoporosis in men
SA Brown, TA Guise
Nature Clinical Practice Urology 2007
Malformaciones vasculares (II). Diagnóstico, histopatología y tratamiento
P Redondo
Actas Dermo-Sifiliográficas 2007
Potential of calcitonin as a novel cotreatment for arthritis
M Perretti, L Mancini
Future Rheumatology 2007
l-Carnitine protects against apoptosis of murine MC3T3-E1 osteoblastic cells
H Xie, SY Tang, H Li, XH Luo, LQ Yuan, D Wang, EY Liao
Amino Acids 2007
Biological options to enhance periprosthetic bone mass
E Tsiridis, Z Gamie, PG Conaghan, PV Giannoudis
Injury 2007
Risedronate and alendronate suppress osteocyte apoptosis following cyclic fatigue loading
H Follet, J Li, RJ Phipps, S Hui, K Condon, DB Burr
Bone 2007
Effect of local delivery of alendronate on bone formation in bioactive glass grafting in rats
S Srisubut, A Teerakapong, T Vattraphodes, S Taweechaisupapong
Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology 2007
Serum OPG and RANKL levels before and after intravenous bisphosphonate treatment in Paget's disease of bone
G Martini, L Gennari, D Merlotti, S Salvadori, MB Franci, S Campagna, A Avanzati, VD Paola, F Valleggi, R Nuti
Bone 2007
Osteonecrosis. What Is New?
MÁ Martínez-Ferrer, P Peris, N Guañabens
Reumatolog ía Cl ínica (English Edition) 2007
Osteocyte apoptosis induces bone resorption and impairs the skeletal response to weightlessness
T Bellido
BoneKEy-Osteovision 2007
Vascular malformations (II). Diagnosis, Pathology, and Treatment
P Redondo
Actas Dermo-Sifiliográficas (English Edition) 2007
Osteonecrosis. ¿Qué hay de nuevo?
MÁ Martínez-Ferrer, P Peris, N Guañabens
Reumatología Clínica 2007
Risedronate prevents the loss of microarchitecture in glucocorticoid-induced osteoporosis in rats
LD Carbonare, F Bertoldo, MT Valenti, S Zordan, S Sella, A Fassina, G Turco, G Realdi, VL Cascio, S Giannini
Journal of Endocrinological Investigation 2007
Signaling and transcriptional regulation in osteoblast commitment and differentiation
W Huang, S Yang, J Shao, YP Li
Frontiers in bioscience : a journal and virtual library 2007
Alendronate Improves Screw Fixation in Osteoporotic Bone:
A Moroni, C Faldini, A Hoang-Kim, F Pegreffi, S Giannini
The Journal of Bone and Joint Surgery. American volume. 2007
Glucocorticoids Induce Osteocyte Apoptosis by Blocking Focal Adhesion Kinase-mediated Survival: EVIDENCE FOR INSIDE-OUT SIGNALING LEADING TO ANOIKIS
LI Plotkin, SC Manolagas, T Bellido
The Journal of biological chemistry 2007
Mechanism of Action, Pharmacokinetic and Pharmacodynamic Profile, and Clinical Applications of Nitrogen-containing Bisphosphonates
DB Kimmel
Journal of dental research 2007
The Interleukin-6 inflammation pathway from cholesterol to aging – Role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases
S Omoigui
Immunity & Ageing 2007
REVIEW: Bone Loss and Its Management in Long-Term Survivors from Allogeneic Stem Cell Transplantation
L Tauchmanovà, A Colao, G Lombardi, B Rotoli, C Selleri
The Journal of clinical endocrinology and metabolism 2007
Osteocyte Apoptosis Is Induced by Weightlessness in Mice and Precedes Osteoclast Recruitment and Bone Loss
JI Aguirre, LI Plotkin, SA Stewart, RS Weinstein, AM Parfitt, SC Manolagas, T Bellido
Journal of Bone and Mineral Research 2006
Ca2+-Dependent Regulation of Calcitonin Gene Expression by the Transcriptional Repressor DREAM
M Matsuda, T Yamamoto, M Hirata
Endocrinology 2006
Glucocorticosteroid-induced spinal osteoporosis: scientific update on pathophysiology and treatment
AW Popp, J Isenegger, EM Buergi, U Buergi, K Lippuner
European Spine Journal 2006
Nothing but skin and bone
FP Ross, AM Christiano
Journal of Clinical Investigation 2006
Glucocorticoid-induced Osteoporosis and Its Treatment
P Pennisi, A Trombetti, R Rizzoli
Clinical Orthopaedics and Related Research 2006
The Pathogenesis, Epidemiology and Management of Glucocorticoid-Induced Osteoporosis
TP Staa
Calcified Tissue International 2006
Mutual augmentation of the induction of the histamine-forming enzyme, histidine decarboxylase, between alendronate and immuno-stimulants (IL-1, TNF, and LPS), and its prevention by clodronate
X Deng, Z Yu, H Funayama, N Shoji, T Sasano, Y Iwakura, S Sugawara, Y Endo
Toxicology and Applied Pharmacology 2006
Antiremodeling Agents Influence Osteoblast Activity Differently in Modeling and Remodeling Sites of Canine Rib
MR Allen, H Follet, M Khurana, M Sato, DB Burr
Calcified Tissue International 2006
Dissociation of the pro-apoptotic effects of bisphosphonates on osteoclasts from their anti-apoptotic effects on osteoblasts/osteocytes with novel analogs
LI Plotkin, SC Manolagas, T Bellido
Bone 2006
Ibandronate: Pharmacology and preclinical studies
RG Russell
Bone 2006
Changes in the RANK ligand/osteoprotegerin system are correlated to changes in bone mineral density in bisphosphonate-treated osteoporotic patients
H Dobnig, LC Hofbauer, V Viereck, B Obermayer-Pietsch, A Fahrleitner-Pammer
Osteoporosis International 2006
The Effects of Antifracture Therapies on the Components of Bone Strength: Assessment of Fracture Risk Today and in the Future
KS Davison, K Siminoski, JD Adachi, DA Hanley, D Goltzman, AB Hodsman, R Josse, S Kaiser, WP Olszynski, A Papaioannou, LG Ste-Marie, DL Kendler, A Tenenhouse, JP Brown
Seminars in Arthritis and Rheumatism 2006
Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody
S Kamijo, A Nakajima, K Ikeda, K Aoki, K Ohya, H Akiba, H Yagita, K Okumura
Biochemical and Biophysical Research Communications 2006
Nekrosen der Kieferknochen unter Bisphosphonattherapie
S Hoefert, H Eufinger
Der Orthopäde 2006
Osteoporosis prevention and therapy: preserving and building strength through bone quality
M Kleerekoper
Osteoporosis International 2006
Advances in the management of corticosteroid-induced osteoporosis with bisphosphonates
JD Ringe, P Farahmand
Clinical Rheumatology 2006
The role of osteocytes and bone microstructure in preventing osteoporotic fractures
JG Hazenberg, D Taylor, TC Lee
Osteoporosis International 2006
Bisphosphonates suppress periosteal osteoblast activity independently of resorption in rat femur and tibia
K Iwata, J Li, H Follet, RJ Phipps, DB Burr
Bone 2006
Drug Insight: bisphosphonates for postmenopausal osteoporosis
RD Chapurlat, PD Delmas
Nature Clinical Practice Endocrinology & Metabolism 2006
Systemic Lupus Erythematosus
M Petri
JCR: Journal of Clinical Rheumatology 2006
Effect of systemic glucocorticoid therapy on bone metabolism: an update
MS Cooper
Expert Review of Endocrinology & Metabolism 2006
Apelin suppresses apoptosis of human osteoblasts
H Xie, LQ Yuan, XH Luo, J Huang, RR Cui, LJ Guo, HD Zhou, XP Wu, EY Liao
Apoptosis 2006
A rapid, high content,in vivo model of glucocorticoid-induced osteoporosis
R Barrett, C Chappell, M Quick, A Fleming
Biotechnology Journal 2006
Effect of Topical Alendronate Treatment on Fixation of Implants Inserted with Bone Compaction
T Jakobsen, S Kold, JE Bechtold, B Elmengaard, K S??balle
Clinical Orthopaedics and Related Research 2006
Osteogenic growth peptide effects on primary human osteoblast cultures: Potential relevance for the treatment of glucocorticoid-induced osteoporosis
A Spreafico, B Frediani, C Capperucci, A Leonini, D Gambera, P Ferrata, S Rosini, AD Stefano, M Galeazzi, R Marcolongo
Journal of Cellular Biochemistry 2006
Association Between Osteonecrosis of the Jaws and Chronic High-Dosage Intravenous Bisphosphonates Therapy
F Graziani, S Cei, FL Ferla, E Cerri, A Itro, M Gabriele
Journal of Craniofacial Surgery 2006
A20 overexpression under control of mouse osteocalcin promoter in MC3T3-E1 cells inhibited tumor necrosis factor-alpha-induced apoptosis
Y QIN, Z ZHANG, L YU, J HE, Y HOU, T LIU, J WU, S WU, L GUO
Acta Pharmacologica Sinica 2006
Postmenopausal osteoporosis. What have we learned since the introduction of bisphosphonates?
S Chaiamnuay, KG Saag
Reviews in Endocrine and Metabolic Disorders 2006
Osteogenic activity of vanadyl(IV)–ascorbate complex: Evaluation of its mechanism of action
AM Cortizo, MS Molinuevo, DA Barrio, L Bruzzone
The International Journal of Biochemistry & Cell Biology 2006
Bisphosphonates activate nucleotide receptors signaling and induce the expression of Hsp90 in osteoblast-like cell lines
M Romanello, N Bivi, A Pines, M Deganuto, F Quadrifoglio, L Moro, G Tell
Bone 2006
Alendronate or Alfacalcidol in Glucocorticoid-Induced Osteoporosis
RN de Nijs, JW Jacobs, WF Lems, RF Laan, A Algra, AM Huisman, E Buskens, CE de Laet, AC Oostveen, PP Geusens, GA Bruyn, BA Dijkmans, JW Bijlsma
New England Journal of Medicine 2006
Choreography from the tomb: An emerging role of dying osteocytes in the purposeful, and perhaps not so purposeful, targeting of bone remodeling
SC Manolagas
BoneKEy-Osteovision 2006
Dynamics of Bone and Cartilage Metabolism
JE Mulder, CA Kulak, E Shane
Dynamics of Bone and Cartilage Metabolism 2006
Glucocorticoid-induced Osteoporosis and Its Treatment:
P Pennisi, A Trombetti, R Rizzoli
Clinical Orthopaedics and Related Research 2006
Rubus coreanus Miq. Extract Promotes Osteoblast Differentiation and Inhibits Bone-Resorbing Mediators in MC3T3-E1 Cells
KH Lee, EM Choi
The American journal of Chinese medicine 2006
Prise en charge de l’ostéoporose cortisonique
P Orcel
La Presse Médicale 2006
Les bisphosphonates oraux dans le traitement de l'ostéoporose postménopausique
T Thomas, V Breuil, K Briot
Revue du Rhumatisme 2006
Use of Bisphosphonates to Improve the Durability of Total Joint Replacements:
AS Shanbhag
The Journal of the American Academy of Orthopaedic Surgeons 2006
Bisphosphonates: From Bench to Bedside
RG Russell
Annals of the New York Academy of Sciences 2006
Molekularmedizinische Grundlagen von para- und autokrinen Regulationsstörungen
D Ganten, K Ruckpaul, J Köhrle
2006
Osteonekrose der Kiefer unter Bisphosphonat-Langzeittherapie
JU Piesold, B Al-Nawas, KA Grötz
Mund- Kiefer- und Gesichtschirurgie 2006
Parathyroid Hormone as an Anabolic Skeletal Therapy:
MR Rubin, JP Bilezikian
Drugs 2005
Alternative bisphosphonate targets and mechanisms of action
JF Bukowski, CC Dascher, H Das
Biochemical and Biophysical Research Communications 2005
Histomorphometric analysis of glucocorticoid-induced osteoporosis
LD Carbonare, F Bertoldo, MT Valenti, S Zenari, M Zanatta, S Sella, S Giannini, VL Cascio
Micron 2005
The bisphosphonate pamidronate on the surface of titanium stimulates bone formation around tibial implants in rats
H Kajiwara, T Yamaza, M Yoshinari, T Goto, S Iyama, I Atsuta, MA Kido, T Tanaka
Biomaterials 2005
Bisphosphonate Modulates Cementoblast Behavior In Vitro
YH Chun, BL Foster, PA Lukasavage, JE Berry, M Zhao, HC Tenenbaum, MJ Somerman
Journal of Periodontology 2005
The decrease of particle-induced osteolysis after a single dose of bisphosphonate
M Knoch, C Wedemeyer, A Pingsmann, F Knoch, G Hilken, C Sprecher, F Henschke, B Barden, F Löer
Biomaterials 2005
Clinical Pharmacology of Potent New Bisphosphonates for Postmenopausal Osteoporosis
RD Chapurlat
Treatments in Endocrinology 2005
The inhibitory effect of alendronate, a nitrogen-containing bisphosphonate on the PI3K-Akt-NFkappaB pathway in osteosarcoma cells
R Inoue, N Matsuki, G Jing, T Kanematsu, K Abe, M Hirata
British Journal of Pharmacology 2005
Prevention and treatment of corticosteroid-induced osteoporosis
J Iwamoto, T Takeda, Y Sato
Yonsei Medical Journal 2005
Regulation of apoptosis in osteoclasts and osteoblastic cells
L Xing, BF Boyce
Biochemical and Biophysical Research Communications 2005
Tiludronate inhibits prostaglandin F2α-induced vascular endothelial growth factor synthesis in osteoblasts
M Yoshida, H Tokuda, A Ishisaki, Y Kanno, A Harada, K Shimuzu, O Kozawa
Molecular and Cellular Endocrinology 2005
Estrogen protects primary osteocytes against glucocorticoid-induced apoptosis
G Gu, TA Hentunen, M Nars, PL Härkönen, HK Väänänen
Apoptosis 2005
Effects of bisphosphonates on proliferation and osteoblast differentiation of human bone marrow stromal cells
F Knoch, C Jaquiery, M Kowalsky, S Schaeren, C Alabre, I Martin, HE Rubash, AS Shanbhag
Biomaterials 2005
Extracellular nucleotides activate Runx2 in the osteoblast-like HOBIT cell line: a possible molecular link between mechanical stress and osteoblasts' response
A Costessi, A Pines, P D'Andrea, M Romanello, G Damante, L Cesaratto, F Quadrifoglio, L Moro, G Tell
Bone 2005
In whom and how to prevent glucocorticoid-induced osteoporosis
JD Adachi, A Papaioannou
Best Practice & Research Clinical Rheumatology 2005
Ein Vergleich der antiresorptiven Effekte von Bisphosphonaten und Statinen auf Polyethylenpartikel-induzierte Osteolysen /A Comparison of the Antiresorptive Effects of Bisphosphonates and Statins on Polyethylene Particle-Induced Osteolysis
F Knoch, C Wedemeyer, A Heckelei, C Sprecher, G Saxler, G Hilken, F Henschke, H Bereiter, F Löer, M Knoch
Biomedizinische Technik/Biomedical Engineering 2005
Apoptosis in glucocorticoid-induced bone disease
RS Weinstein, SC Manolagas
Current Opinion in Internal Medicine 2005
Calmodulin is a critical regulator of osteoclastic differentiation, function, and survival
EC Seales, KJ Micoli, JM McDonald
Journal of Cellular Biochemistry 2005
Kieferknochennekrosen als mögliche unerwünschte Wirkung von Bisphosphonaten
S Hoefert, H Eufinger
Mund-, Kiefer- und Gesichtschirurgie 2005
Effects of various antireabsorptive treatments on bone mineral density in hypogonadal young women after allogeneic stem cell transplantation
L Tauchmanovà, GD Simone, T Musella, F Orio, P Ricci, C Nappi, G Lombardi, A Colao, B Rotoli, C Selleri
Bone Marrow Transplantation 2005
Stimulation of bone formation by zoledronic acid in particle-induced osteolysis
C Wedemeyer, F Knoch, A Pingsmann, G Hilken, C Sprecher, G Saxler, F Henschke, F Löer, M Knoch
Biomaterials 2005
The effect of simvastatin on polyethylene particle-induced osteolysis
F Knoch, A Heckelei, C Wedemeyer, G Saxler, G Hilken, F Henschke, F Löer, M Knoch
Biomaterials 2005
Promotion of bone formation by simvastatin in polyethylene particle-induced osteolysis
F Knoch, C Wedemeyer, A Heckelei, G Saxler, G Hilken, J Brankamp, T Sterner, S Landgraeber, F Henschke, F Löer, M Knoch
Biomaterials 2005
Bone Healing in Children With Osteogenesis Imperfecta Treated With Bisphosphonates
J Pizones, H Plotkin, JI Parra-Garcia, P Alvarez, P Gutierrez, A Bueno, A Fernandez-Arroyo
Journal of Pediatric Orthopaedics 2005
Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration
B Peter, DP Pioletti, S Laïb, B Bujoli, P Pilet, P Janvier, J Guicheux, PY Zambelli, JM Bouler, O Gauthier
Bone 2005
Prevention and treatment of glucocorticoid-induced osteoporosis in 2005
P Orcel
Joint Bone Spine 2005
Bone Disease of Organ Transplantation
MR Rubin, JP Billezkian
Bone Disease of Organ Transplantation 2005
Prise en charge de l'ostéoporose cortisonique en 2005
P Orcel
Revue du Rhumatisme 2005
The influence of alendronate on bone formation after autogenous free bone grafting in rats
H Altundal, B Gursoy
Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology 2005
Effects of neridronate treatment in elderly women with osteoporosis
T Cascella, T Musella, F Orio, S Palomba, G Bifulco, C Nappi, G Lombardi, A Colao, L Tauchmanova
Journal of Endocrinological Investigation 2005
The inhibitory effect of bisphosphonates on glucocorticoid‐induced RANKL expression in human cells
A Kobayashi, F Hirano, I Makino
Scandinavian Journal of Rheumatology 2005
Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs
LI Plotkin, I Mathov, JI Aguirre, AM Parfitt, SC Manolagas, T Bellido
American journal of physiology. Cell physiology 2005
Morbus Bechterew
A Felkenbach
2005
Bone Resorption
F Bronner, MC Farach-Carson, J Rubin
2005
Short-Term Zoledronic Acid Treatment Increases Bone Mineral Density and Marrow Clonogenic Fibroblast Progenitors after Allogeneic Stem Cell Transplantation
L Tauchmanovà, P Ricci, B Serio, G Lombardi, A Colao, B Rotoli, C Selleri
The Journal of clinical endocrinology and metabolism 2005
Kieferknochennekrosen als mögliche unerwünschte Wirkung von Bisphosphonaten
S Hoefert, H Eufinger
Mund- Kiefer- und Gesichtschirurgie 2005
A crucial role of Caspase-3 in osteogenic differentiation of bone marrow stromal stem cells
Masako Miura, Xiao-Dong Chen, Matthew R. Allen, Yanming Bi, Stan Gronthos, Byoung-Moo Seo, Saquib Lakhani, Richard A. Flavell, Xin-Hua Feng, Pamela Gehron Robey, Marian Young, Songtao Shi
Journal of Clinical Investigation 2004
Bisphosphonates: Environmental protection for the joint?
SR Goldring, EM Gravallese
Arthritis & Rheumatism 2004
Drugs Used to Treat Osteoporosis: The Critical Need for a Uniform Nomenclature Based on Their Action on Bone Remodeling
BL Riggs, AM Parfitt
Journal of Bone and Mineral Research 2004
Steroid-free medium discloses oestrogenic effects of the bisphosphonate clodronate on breast cancer cells
F Journe, C Chaboteaux, JC Dumon, G Leclercq, G Laurent, JJ Body
British Journal of Cancer 2004
Kinase-mediated transcription, activators of nongenotropic estrogen-like signaling (ANGELS), and osteoporosis: A different perspective on the HRT dilemma
SC Manolagas, S Kousteni, JR Chen, M Schuller, L Plotkin, T Bellido
Kidney International 2004
Preventing osteoporotic fractures with antiresorptive therapy: implications of microarchitectural changes
S Boonen, P Haentjens, L Vandenput, D Vanderschueren
Journal of Internal Medicine 2004
Bone safety of long-term bisphosphonate treatment
G Rodan, A Reszka, E Golub, R Rizzoli
Current Medical Research and Opinion 2004
Osteoblast proliferation and maturation by bisphosphonates
GI Im, SA Qureshi, J Kenney, HE Rubash, AS Shanbhag
Biomaterials 2004
Long-term effects of neridronate on human osteoblastic cell cultures
B Frediani, A Spreafico, C Capperucci, F Chellini, D Gambera, P Ferrata, F Baldi, P Falsetti, A Santucci, L Bocchi, R Marcolongo
Bone 2004
Calcitonin Therapy in Osteoporosis
M Mu??oz-Torres, G Alonso, PM Raya
Treatments in Endocrinology 2004
Zoledronic acid up-regulates bone sialoprotein expression in osteoblastic cells through Rho GTPase inhibition
M Chaplet, C Detry, C Deroanne, LW Fisher, V Castronovo, A Bellahcéne
Biochemical Journal 2004
The efficacy of acute administration of pamidronate on the conservation of bone mass following severe burn injury in children: a double-blind, randomized, controlled study
GL Klein, SJ Wimalawansa, G Kulkarni, DJ Sherrard, AP Sanford, DN Herndon
Osteoporosis International 2004
Matrix Metalloproteinases (MMPs) Safeguard Osteoblasts from Apoptosis during Transdifferentiation into Osteocytes: MT1-MMP Maintains Osteocyte Viability
MA Karsdal, TA Andersen, L Bonewald, C Christiansen
DNA and Cell Biology 2004
Periosteum: biology, regulation, and response to osteoporosis therapies
MR Allen, JM Hock, DB Burr
Bone 2004
Calcitonin Receptor Gene and Breast Cancer: Quantitative Analysis with Laser Capture Microdissection
X Wang, M Nakamura, I Mori, K Takeda, Y Nakamura, H Utsunomiya, G Yoshimura, T Sakurai, K Kakudo
Breast Cancer Research and Treatment 2004
Selective in vitro antioxidant properties of bisphosphonates
EJ Dombrecht, P Cos, DV Berghe, JF Offel, AJ Schuerwegh, CH Bridts, WJ Stevens, LS Clerck
Biochemical and Biophysical Research Communications 2004
Bioprocess-centered molecular design (BMD) for the efficient production of an interfacially active peptide
G Morreale, EG Lee, DB Jones, AP Middelberg
Biotechnology and Bioengineering 2004
Systemic and local ibandronate enhance screw fixation
B Skoglund, J Holmertz, P Aspenberg
Journal of Orthopaedic Research 2004
Intravenous bisphosphonate therapy for osteoporosis: Where do we stand?
HG Bone, W Schurr
Current Osteoporosis Reports 2004
The treatment of glucocorticoid-induced osteoporosis
D Cohen, JD Adachi
The Journal of Steroid Biochemistry and Molecular Biology 2004
Fas/CD95 is associated with glucocorticoid-induced osteocyte apoptosis
G Kogianni, V Mann, F Ebetino, M Nuttall, P Nijweide, H Simpson, B Noble
Life Sciences 2004
Osteoarthritis and osteoporosis in postmenopausal women: clinical similarities and differences
D Avci, GA Bachmann
Menopause 2004
Protective and anti-arthritic effects of deer antler aqua-acupuncture (DAA), inhibiting dihydroorotate dehydrogenase, on phosphate ions-mediated chondrocyte apoptosis and rat collagen-induced arthritis
KS Kim, YH Choi, KH Kim, YC Lee, CH Kim, SH Moon, SG Kang, YG Park
International Immunopharmacology 2004
Postmenopausal osteoporosis and alendronate
FR Pérez-López
Maturitas 2004
Effect of D-003, a Mixture of Very High Molecular Weight Aliphatic Acids, on Prednisolone-Induced Osteoporosis in Sprague-Dawley Rats:
M Noa, S Mendoza, R M??s, N Mendoza, F Le??n
Drugs in R & D 2004
Effect of pamidronate on new vertebral fractures and bone mineral density in patients with malignant lymphoma receiving chemotherapy
SH Kim, SK Lim, JS Hahn
The American Journal of Medicine 2004
Principles of Gender-Specific Medicine
G Supinski, LA Callahan
Principles of Gender-Specific Medicine 2004
The effect of alendronate on resorption of the alveolar bone following tooth extraction
H Altundal, Ö Güvener
International Journal of Oral and Maxillofacial Surgery 2004
Transient Versus Sustained Phosphorylation and Nuclear Accumulation of ERKs Underlie Anti- Versus Pro-apoptotic Effects of Estrogens
JR Chen, LI Plotkin, JI Aguirre, L Han, RL Jilka, S Kousteni, T Bellido, SC Manolagas
The Journal of biological chemistry 2004
The Skeleton
EJ Massaro, JM Rogers
2004
Nutrition and Bone Health
MF Holick, B Dawson-Hughes
2004
Effects of 1α,25-Dihydroxyvitamin D3 and Growth Hormone on Apoptosis and Proliferation in UMR 106 Osteoblast-Like Cells
O Morales, MK Samuelsson, U Lindgren, LA Haldosén
Endocrinology 2004
CD40 ligand blocks apoptosis induced by tumor necrosis factor alpha, glucocorticoids, and etoposide in osteoblasts and the osteocyte-like cell line murine long bone osteocyte-Y4
SS Ahuja, S Zhao, T Bellido, LI Plotkin, F Jimenez, LF Bonewald
Endocrinology 2003
Osteoclastogenesis, Bone Resorption, and Osteoclast-Based Therapeutics
M Zaidi, HC Blair, BS Moonga, E Abe, CL Huang
Journal of Bone and Mineral Research 2003
Overexpression of Nell-1, a Craniosynostosis-Associated Gene, Induces Apoptosis in Osteoblasts During Craniofacial Development
X Zhang, D Carpenter, N Bokui, C Soo, S Miao, T Truong, B WU, I Chen, H Vastardis, K Tanizawa, SI Kuroda, K Ting
Journal of Bone and Mineral Research 2003
Perspectives on osteoporosis in pediatric inflammatory bowel disease
M Harpavat, DJ Keljo
Current Gastroenterology Reports 2003
Effect of pamidronate on the stimulation of macrophage TNF-α release by ultra-high-molecular-weight polyethylene particles: a role for apoptosis
OL Huk, DJ Zukor, J Antoniou, A Petit
Journal of Orthopaedic Research 2003
Understanding osteoclast formation and function: implications for future therapies for osteoporosis
M Zaidi, BS Moonga, L Sun, S Epstein, CL Huang, E Abe
Current Opinion in Orthopaedics 2003
Bisphosphonates antagonise bone growth factors' effects on human breast cancer cells survival
O Fromigue, N Kheddoumi, JJ Body
British Journal of Cancer 2003
Bisphosphonate Induced Growth Inhibition of Breast Cancer Cells is Augmented by p38 Inhibition
M Merrell, C Suarez-Cuervo, KW Harris, HK Väänänen, KS Selander
Breast Cancer Research and Treatment 2003
RANK-Fc: A therapeutic antagonist for RANK-L in myeloma
EM Sordillo, RN Pearse
Cancer 2003
Apoptosis: an introduction for the endodontist
PG Satchell, JL Gutmann, DE Witherspoon
International Endodontic Journal 2003
Prevention of Glucocorticoid-Induced Apoptosis in Osteocytes and Osteoblasts by Calbindin-D28k
Y Liu, A Porta, X Peng, K Gengaro, EB Cunningham, H Li, LA Dominguez, T Bellido, S Christakos
Journal of Bone and Mineral Research 2003
Osteocyte biology
LF Bonewald
Current Opinion in Orthopaedics 2003
Clodronate stimulates osteoblast differentiation in ST2 and MC3T3-E1 cells and rat organ cultures
F Itoh, S Aoyagi, H Furihata-Komatsu, M Aoki, H Kusama, M Kojima, H Kogo
European Journal of Pharmacology 2003
Inhibition of osteoblast apoptosis by thrombin
CN Pagel, MR de Niese, LA Abraham, C Chinni, SJ Song, RN Pike, EJ Mackie
Bone 2003
Bilateral Femoral Head Osteonecrosis After Septic Shock and Multiorgan Failure
MJ Bolland, G Hood, ST Bastin, AR King, A Grey
Journal of Bone and Mineral Research 2003
Determinants of Bone Strength
GM Kiebzak, PD Miller
Journal of Bone and Mineral Research 2003
Pamidronate is superior to ibandronate in decreasing bone resorption, interleukin-6 and β2-microglobulin in multiple myeloma
E Terpos, N Viniou, J la Fuente, J Meletis, E Voskaridou, C Karkantaris, G Vaiopoulos, J Palermos, X Yataganas, JM Goldman, A Rahemtulla
European Journal of Haematology 2003
Biochemical markers of bone metabolism in bone marrow edema syndrome of the hip
CE Berger, AH Kröner, MB Minai-Pour, E Ogris, A Engel
Bone 2003
Prevention and Treatment of Glucocorticoid-Induced Osteoporosis: A Comparison of Calcitriol, Vitamin D Plus Calcium, and Alendronate Plus Calcium
PN Sambrook, M Kotowicz, P Nash, CB Styles, V Naganathan, KN Henderson-Briffa, JA Eisman, GC Nicholson
Journal of Bone and Mineral Research 2003
A new bisphosphonate, YM529 induces apoptosis in HL60 cells by decreasing phosphorylation of single survival signal ERK
S Nishida, Y Fujii, S Yoshioka, S Kikuichi, M Tsubaki, K Irimajiri
Life Sciences 2003
Biology of the basic multicellular unit and the pathophysiology of osteoporosis
RL Jilka
Medical and Pediatric Oncology 2003
Glucocorticoid-induced osteoporosis: pathophysiological data and recent treatments
MH Lafage-Proust, B Boudignon, T Thomas
Joint Bone Spine 2003
Prévention et traitement de l’ostéoporose cortisonique
C Roux, P Orcel
La Revue de Médecine Interne 2003
Understanding osteoclast formation and function: implications for future therapies for osteoporosis:
M Zaidi, BS Moonga, L Sun, S Epstein, CL Huang, E Abe
Current Opinion in Orthopaedics 2003
La calcitonina hoy
HR Lenza
Revista Clínica Española 2003
Ostéoporose cortico-induite : données physiopathologiques et thérapeutiques récentes
MH Lafage-Proust, B Boudignon, T Thomas
Revue du Rhumatisme 2003
Calcitonin in the Treatment of Transient Osteoporosis of the Hip
TK Arayssi, HA Tawbi, IM Usta, MH Hourani
Seminars in Arthritis and Rheumatism 2003
Incadronate Amplifies Prostaglandin F 2α -induced Vascular Endothelial Growth Factor Synthesis in Osteoblasts: ENHANCEMENT OF MAPK ACTIVITY
H Tokuda, A Harada, K Hirade, H Matsuno, H Ito, K Kato, Y Oiso, O Kozawa
The Journal of biological chemistry 2003
Beyond the gap: functions of unpaired connexon channels
DA Goodenough, DL Paul
Nature Reviews Molecular Cell Biology 2003
Inflammatory Bowel Disease: From Bench to Bedside
SR Targan, F Shanahan, LC Karp
2003
Handbook of Histology Methods for Bone and Cartilage
YH An, KL Martin
2003
Promotion of Osteoclast Survival and Antagonism of Bisphosphonate-Induced Osteoclast Apoptosis by Glucocorticoids
Robert S. Weinstein, Jin-Ran Chen, Cara C. Powers, Reid D. Landes, Robert L. Jilka, A. Michael Parfitt, Stavros C. Manolagas
Journal of Clinical Investigation 2002
Age-Related Osteoporosis in Biglycan-Deficient Mice Is Related to Defects in Bone Marrow Stromal Cells
XD Chen, S Shi, T Xu, PG Robey, MF Young
Journal of Bone and Mineral Research 2002
Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue
GG Reinholz, B Getz, ES Sanders, MY Karpeisky, NS Padyukova, SN Mikhailov, JN Ingle, TC Spelsberg
Breast Cancer Research and Treatment 2002
In vitro effects of combination chemotherapy on osteoblasts: implications for osteopenia in childhood malignancy
JH Davies, BA Evans, ME Jenney, JW Gregory
Bone 2002
Different effects of antiresorptive therapies on vertebral and nonvertebral fractures in postmenopausal osteoporosis
PD Delmas
Bone 2002
Spatial Distribution of Bax and Bcl-2 in Osteocytes After Bone Fatigue: Complementary Roles in Bone Remodeling Regulation?
O Verborgt, NA Tatton, RJ Majeska, MB Schaffler
Journal of Bone and Mineral Research 2002
Calcitonin: The Other Thyroid Hormone
AM Inzerillo, M Zaidi, CL Huang
Thyroid 2002
Noninvasive loading of the murine tibia: an in vivo model for the study of mechanotransduction
TS Gross, S Srinivasan, CC Liu, TL Clemens, SD Bain
Journal of Bone and Mineral Research 2002
Insulin secretion and sensitivity in space flight
BW Tobin, PN Uchakin, SK Leeper-Woodford
Nutrition 2002
Bisphosphonates Pamidronate and Zoledronic Acid Stimulate Osteoprotegerin Production by Primary Human Osteoblasts
V Viereck, G Emons, V Lauck, KH Frosch, S Blaschke, C Gründker, LC Hofbauer
Biochemical and Biophysical Research Communications 2002
MLO-Y4 Osteocyte-Like Cells Support Osteoclast Formation and Activation
S Zhao, Y Kato, Y Zhang, S Harris, SS Ahuja, LF Bonewald
Journal of Bone and Mineral Research 2002
Effects of a single infusion of pamidronate prior to liver transplantation: a bone histomorphometric study
S Vedi, M Ninkovic, NJ Garrahan, GJ Alexander, JE Compston
Transplant International 2002
Prevention of Bone Loss in Ovariectomized Rats by Combined Treatment With Risedronate and 1α,25-Dihydroxyvitamin D3
RG Erben, L Mosekilde, JS Thomsen, K Weber, K Stahr, A Leyshon, SY Smith, R Phipps
Journal of Bone and Mineral Research 2002
Pharmacotherapy of osteoporosis
M KOIDA
Folia Pharmacologica Japonica 2002
Intravenous pamidronate in the treatment of transient osteoporosis of the hip
M Varenna, F Zucchi, L Binelli, S Failoni, M Gallazzi, L Sinigaglia
Bone 2002
Intravenous Zoledronic Acid in Postmenopausal Women with Low Bone Mineral Density
IR Reid, JP Brown, P Burckhardt, Z Horowitz, P Richardson, U Trechsel, A Widmer, JP Devogelaer, JM Kaufman, P Jaeger, JJ Body, ML Brandi, J Broell, RD Micco, AR Genazzani, D Felsenberg, J Happ, MJ Hooper, J Ittner, G Leb, H Mallmin, T Murray, S Ortolani, A Rubinacci, M Sääf, G Samsioe, L Verbruggen, PJ Meunier
New England Journal of Medicine 2002
Osteocytes inhibit osteoclastic bone resorption through transforming growth factor-?: Enhancement by estrogen
TJ Heino, TA Hentunen, HK V��n�nen
Journal of Cellular Biochemistry 2002
Alendronate Treatment for Infants with Osteogenesis Imperfecta: Demonstration of Efficacy in a Mouse Model
EA McCarthy, CL Raggio, MD Hossack, EA Miller, S Jain, AL Boskey, NP Camacho
Pediatric Research 2002
Forty years of calcitonin--where are we now? A tribute to the work of Iain Macintyre, FRS
M Zaidi, AM Inzerillo, BS Moonga, PJ Bevis, CL Huang
Bone 2002
Traitement médicamenteux des ostéoporoses post-ménopausiques et cortisoniques
C Roux
Revue du Rhumatisme 2002
Alendronate increases bone mineral density in long-term renal transplant recipients
M Koc, S Tuglular, H Arikan, C Ozener, E Akoglu
Transplantation Proceedings 2002
Histomorphometric Analysis of Bone Biopsies from the Iliac Crest of Adults with Cystic Fibrosis
SL Elkin, S Vedi, S Bord, NJ Garrahan, ME Hodson, JE Compston
American journal of respiratory and critical care medicine 2002
Bisphosphonates influence the proliferation and the maturation of normal human osteoblasts
O Fromigué, JJ Body
Journal of Endocrinological Investigation 2002
Matrix Metalloproteinase-dependent Activation of Latent Transforming Growth Factor-β Controls the Conversion of Osteoblasts into Osteocytes by Blocking Osteoblast Apoptosis
MA Karsdal, L Larsen, MT Engsig, H Lou, M Ferreras, A Lochter, JM Delaissé, NT Foged
The Journal of biological chemistry 2002
Recent Advances in Glucocorticoid Receptor Action
AC Cato, H Schäcke, K Asadullah
2002
Statins as modulators of bone formation
CJ Edwards, TD Spector
Arthritis Research & Therapy 2002
Genetic Approaches to Determine the Role of Glucocorticoid Signaling in Osteoblasts
JR Harrison, HW Woitge, BE Kream
Endocrine 2002
Glucocorticoid-induced osteoporosis
R Kumar
Current Opinion in Nephrology and Hypertension 2001
Transplantation osteoporosis
A Cohen, E Shane
Current Opinion in Endocrinology & Diabetes 2001
Bisphosphonates: mechanisms of action
H Fleisch
Expert Opinion on Therapeutic Patents 2001
Bisphosphonate-Induced, Hemichannel-Mediated, Anti-Apoptosis Through the Src/ERK Pathway: A Gap Junction-Independent Action of Connexin43
LI Plotkin, T Bellido
Cell Communication and Adhesion 2001
Perspective: Reconsidering the Effects of Antiresorptive Therapies in Reducing Osteoporotic Fracture
CH Chesnut, CJ Rosen
Journal of Bone and Mineral Research 2001
Extracellular Signal-Regulated Kinases and Calcium Channels Are Involved in the Proliferative Effect of Bisphosphonates on Osteoblastic Cells In Vitro
I Mathov, LI Plotkin, CL Sgarlata, J Leoni, T Bellido
Journal of Bone and Mineral Research 2001
Nongenotropic, Sex-Nonspecific Signaling through the Estrogen or Androgen Receptors
S Kousteni, T Bellido, LI Plotkin, CA O'Brien, DL Bodenner, L Han, K Han, GB DiGregorio, JA Katzenellenbogen, BS Katzenellenbogen, PK Roberson, RS Weinstein, RL Jilka, SC Manolagas
Cell 2001
Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line
PS Mackie, JL Fisher, H Zhou, PF Choong
British Journal of Cancer 2001
Phosphate ions mediate chondrocyte apoptosis through a plasma membrane transporter mechanism
K Mansfield, CC Teixeira, CS Adams, IM Shapiro
Bone 2001
Incadronate and Etidronate Accelerate Phosphate-Primed Mineralization of MC4 Cells via ERK1/2-Cbfal Signaling Pathway in a Ras-Independent Manner: Further Involvement of Mevalonate-Pathway Blocade for Incadronate
T Fujita, N Izumo, R Fukuyama, T Meguro, C Yasutomi, H Nakamuta, M Koida
The Japanese Journal of Pharmacology 2001
The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro
J Sonnemann, V Eckervogt, B Truckenbrod, J Boos, W Winkelmann, F Valen
Anti-Cancer Drugs 2001
Apoptosis may determine the release of skeletal alkaline phosphatase activity from human osteoblast-line cells
JR Farley, B Stilt-Coffing
Calcified Tissue International 2001
Pamidronate increases markers of bone formation in patients with multiple myeloma in plateau phase under interferon-alpha treatment
E Terpos, J Palermos, N Viniou, G Vaiopoulos, J Meletis, X Yataganas
Calcified Tissue International 2001
Abnormal bone turnover in long-standing Crohn's disease in remission
EJ Schoon, BG Geerling, IM van Dooren, LJ Schurgers, C Vermeer, RJ Brummer, RW Stockbrugger
Alimentary Pharmacology & Therapeutics 2001
Can Bisphosphonates Be Given to Patients with Fractures?
H Fleisch
Journal of Bone and Mineral Research 2001
How do antiresorptive agents reduce fracture risk?
E Seeman
BoneKEy-Osteovision 2001
Problèmes méthodologiques de la mesure de densité osseuse par absorptiométrie biphotonique
C Roux, M Dougados
ITBM-RBM 2001
La situación actual de la utilización de la calcitonina en la osteopenia/osteoporosis
FH Carranza
Revista Clínica Española 2001
Manipulating Programmed Cell Death for Better Living!
SC Manolagas
Science signaling 2001
Effect of 17ß-estradiol or alendronate on the bone densitometry, bone histomorphometry and bone metabolism of ovariectomized rats
LH Paz, V Falco, NC Teng, LM Reis, RM Pereira, V Jorgetti
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] 2001
TREATMENT OF ESTABLISHED BONE LOSS AFTER RENAL TRANSPLANTATION WITH ETIDRONATE1:
DJ Arlen, K Lambert, G Ioannidis, JD Adachi
Transplantation 2001
Glucocorticoid-induced osteoporosis
R S Weinstein
Reviews in Endocrine and Metabolic Disorders 2001
Prolonged, Symptomatic Hypocalcemia with Pamidronate Administration and Subclinical Hypoparathyroidism
A Mishra, L Wong, J Jonklaas
Endocrine 2001
Alendronate Stimulates Collagenase 3 Expression in Osteoblasts by Posttranscriptional Mechanisms
S Varghese, E Canalis
Journal of Bone and Mineral Research 2000
True Strength
RS Weinstein
Journal of Bone and Mineral Research 2000
Osteogenesis Imperfecta
F Antoniazzi, M Mottes, P Fraschini, PC Brunelli, L Tat??
Paediatric Drugs 2000
Therapeutic patenting for glucocorticoid-induced osteoporosis
MS Cooper, PM Stewart
Expert Opinion on Therapeutic Patents 2000
Corticosteroids and Fractures: A Close Encounter of the Third Cell Kind
SC Manolagas
Journal of Bone and Mineral Research 2000
Apoptosis and osteoporosis
RS Weinstein, SC Manolagas
The American Journal of Medicine 2000
Etidronate inhibits human osteoblast apoptosis by inhibition of pro-apoptotic factor(s) produced by activated T cells
Y Abe, A Kawakami, T Nakashima, E Ejima, K Fujiyama, T Kiriyama, A Ide, N Sera, T Usa, T Tominaga, K Ashizawa, N Yokoyama, K Eguchi
The Journal of laboratory and clinical medicine 2000
Statins: lower lipids and better bones?
MJ Rogers
Nature Medicine 2000
Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1
SC Manolagas
Endocrine reviews 2000
Calbindin-D 28k Is Expressed in Osteoblastic Cells and Suppresses Their Apoptosis by Inhibiting Caspase-3 Activity
T Bellido, M Huening, M Raval-Pandya, SC Manolagas, S Christakos
The Journal of biological chemistry 2000
Bisphosphonates prevent osteocyte apoptosis
M Rogers
Arthritis Research & Therapy 1999
Corticosteroid-Induced Osteoporosis
JD Adachi
The American Journal of the Medical Sciences 1997
Osteoporosis
DL Glaser, FS Kaplan
Spine 1997
Rheumatology
RA Asherson, R Cervera, DP D'Cruz, GR Hughes
Postgraduate medical journal 1991

← Previous 1 2 3 4 … 27 28 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Referenced in 3 patents
197 readers on Mendeley
1 readers on CiteULike
See more details