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Takeshi Yoneshiro, … , Toshihiko Iwanaga, Masayuki Saito
Published July 15, 2013
Citation Information: J Clin Invest. 2013;123(8):3404-3408. https://doi.org/10.1172/JCI67803.
Citation Information: J Clin Invest. 2013;123(8):3404-3408. https://doi.org/10.1172/JCI67803.
Abstract
Brown adipose tissue (BAT) burns fat to produce heat when the body is exposed to cold and plays a role in energy metabolism. Using fluorodeoxyglucose-positron emission tomography and computed tomography, we previously reported that BAT decreases with age and thereby accelerates age-related accumulation of body fat in humans. Thus, the recruitment of BAT may be effective for body fat reduction. In this study, we examined the effects of repeated stimulation by cold and capsinoids (nonpungent capsaicin analogs) in healthy human subjects with low BAT activity. Acute cold exposure at 19°C for 2 hours increased energy expenditure (EE). Cold-induced increments of EE (CIT) strongly correlated with BAT activity independently of age and fat-free mass. Daily 2-hour cold exposure at 17°C for 6 weeks resulted in a parallel increase in BAT activity and CIT and a concomitant decrease in body fat mass. Changes in BAT activity and body fat mass were negatively correlated. Similarly, daily ingestion of capsinoids for 6 weeks increased CIT. These results demonstrate that human BAT can be recruited even in individuals with decreased BAT activity, thereby contributing to body fat reduction.
Authors
Takeshi Yoneshiro, Sayuri Aita, Mami Matsushita, Takashi Kayahara, Toshimitsu Kameya, Yuko Kawai, Toshihiko Iwanaga, Masayuki Saito
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Citations to this article (489)
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|
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|
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|
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|
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|
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|
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|
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|
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Sugino T, Taguchi K, Yanase T, Unno R, Ando R, Yasui T |
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|
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Sugiura C, Sato M, Tanaka S, Okumura N, Terao A |
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|
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McInnis K, Larocque A, Beauregard N, Hintze LJ, Finlayson G, Haman F, Doucet É |
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|
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|
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|
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|
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|
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|
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|
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Eberhart T, Stanley FU, Ricci L, Chirico T, Ferrarese R, Sisti S, Scagliola A, Baj A, Badurek S, Sommer A, Culp-Hill R, Dzieciatkowska M, Shokry E, Sumpton D, D\u2019Alessandro A, Clementi N, Mancini N, Cardaci S |
Cell Death and Disease | 2024 |
|
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Riera CE |
Diabetes | 2024 |
|
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Tabei S, Chamorro R, Meyhöfer SM, Wilms B |
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|
Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease
Ito R, Xie S, Tumenjargal M, Sugahara Y, Yang C, Takahashi H, Arai M, Inoue SI, Uchida A, Nakano K, Choi H, Yang G, Zhao Y, Yamaguchi R, Jin H, Sagae H, Wada Y, Tanaka T, Kimura H, Kodama T, Aburatani H, Takeda K, Inagaki T, Osborne TF, Yoneshiro T, Matsumura Y, Sakai J |
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|
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Kowald A, Palmer D, Secci R, Fuellen G |
Aging and disease | 2024 |
|
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function.
Khani S, Topel H, Kardinal R, Tavanez AR, Josephrajan A, Larsen BDM, Gaudry MJ, Leyendecker P, Egedal NM, Güller AS, Stanic N, Ruppert PMM, Gaziano I, Hansmeier NR, Schmidt E, Klemm P, Vagliano LM, Stahl R, Duthie F, Krause JH, Bici A, Engelhard CA, Gohlke S, Frommolt P, Gnad T, Rada-Iglesias A, Pradas-Juni M, Schulz TJ, Wunderlich FT, Pfeifer A, Bartelt A, Jastroch M, Wachten D, Kornfeld JW |
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|
Ameliorative effect of bofutsushosan (Fangfengtongshengsan) extract on the progression of aging-induced obesity.
Saeki T, Yamamoto S, Akaki J, Tanaka T, Nakasone M, Ikeda H, Wang W, Inoue M, Manse Y, Ninomiya K, Morikawa T |
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|
BCAA nitrogen flux in brown fat controls metabolic health independent of thermogenesis
Verkerke AR, Wang D, Yoshida N, Taxin ZH, Shi X, Zheng S, Li Y, Auger C, Oikawa S, Yook JS, Granath-Panelo M, He W, Zhang GF, Matsushita M, Saito M, Gerszten RE, Mills EL, Banks AS, Ishihama Y, White PJ, McGarrah RW, Yoneshiro T, Kajimura S |
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|
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Benvie AM, Berry DC |
2024 | |
|
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Stojchevski R, Chandrasekaran P, Hadzi-Petrushev N, Mladenov M, Avtanski D |
International journal of molecular sciences | 2024 |
|
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Baba Y, Azuma N, Saito Y, Takahashi K, Matsui R, Takara T |
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|
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2024 | |
|
Triiodothyronine (T3) promotes browning of white adipose through inhibition of the PI3K/AKT signalling pathway
Huang L, Guo Z, Huang M, Zeng X, Huang H |
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|
Mechanisms and metabolic consequences of adipocyte progenitor replicative senescence
Lin T, Mohammad A, Kolonin MG, Eckel-Mahan KL |
Immunometabolism (Cobham, Surrey) | 2024 |
|
Effects of Environmental Conditions on Athlete’s Cardiovascular System
Segreti A, Celeski M, Guerra E, Crispino SP, Vespasiano F, Buzzelli L, Fossati C, Papalia R, Pigozzi F, Grigioni F |
Journal of Clinical Medicine | 2024 |
|
Inter-Organ Communication Involved in Brown Adipose Tissue Thermogenesis.
Takahashi K, Yamada T, Katagiri H |
Advances in experimental medicine and biology | 2024 |
|
Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue.
Lee D, Benvie AM, Steiner BM, Kolba NJ, Ford JG, McCabe SM, Jiang Y, Berry DC |
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|
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Mao L, Lu J, Hou Y, Nie T |
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|
Reversing Pdgfrβ signaling restores metabolically active beige adipocytes by alleviating ILC2 suppression in aged and obese mice.
Benvie AM, Berry DC |
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|
Association of brown adipose tissue activity with circulating sex hormones and fibroblast growth factor 21 in the follicular and luteal phases in young women.
Taniguchi H, Hashimoto Y, Dowaki N, Nirengi S |
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|
Preliminary study on the effects of boysenberry juice intake on brown adipose tissue activity in healthy adults.
Furuuchi R, Kato S, Maejima D, Amano T, Fujiki S, Shimizu I, Minamino T |
Scientific reports | 2024 |
|
Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders
de Oliveira Silva T, Lunardon G, Lino CA, de Almeida Silva A, Zhang S, Irigoyen MC, Lu YW, Mably JD, Barreto-Chaves ML, Wang DZ, Diniz GP |
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|
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Honda K, Tanoue T, Nagayama M, Roochana A, Zimmerman S, Ashenberg O, Jain T, Sasajima S, Takeshita K, Hetherington N, Okahashi N, Ueda M, Konishi M, Nakayama Y, Minoda A, Skelly A, Minokoshi Y, Pucci N, Mende D, Arita M, Yamamoto H, Watanabe S, Miura K, Suda W, Atarashi K, Matsushita M, Kajimura S, Plichta D, Saito M, Xavier R |
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|
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|
Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis
Zhao Z, Hu L, Song B, Jiang T, Wu Q, Lin J, Li X, Cai Y, Li J, Qian B, Liu S, Lang J, Yang Z |
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|
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|
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Cypess AM, Cannon B, Nedergaard J, Kazak L, Chang DC, Krakoff J, Tseng YH, Scheele C, Boucher J, Petrovic N, Blondin DP, Carpentier AC, Virtanen KA, Kooijman S, Rensen PC, Cero C, Kajimura S |
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|
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Brown Z, Yoneshiro T |
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|
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Shi Z, Xiong S, Hu R, Wang Z, Park J, Qian Y, Wang J, Bhalla P, Velupally N, Song Q, Song Z, Jeon MS, Zhang KK, Xie L, Layden BT, Ong SG, Jiang Y |
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|
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|
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|
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Mukai T, Kusudo T |
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|
Central angiotensin 1–7 triggers brown fat thermogenesis
Evangelista FS, Bartness TJ |
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|
Age-dependent Pdgfrβ signaling drives adipocyte progenitor dysfunction to alter the beige adipogenic niche in male mice.
Benvie AM, Lee D, Steiner BM, Xue S, Jiang Y, Berry DC |
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|
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Paz HA, Pilkington A, Loy HD, Zhong Y, Shankar K, Wankhade UD |
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|
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Ginting RP, Lee JM, Lee MW |
Cells | 2023 |
|
Brown Adipose Tissue Transplantation.
Gunawardana S |
Methods in molecular biology (Clifton, N.J.) | 2023 |
|
Brown Adipose Tissue: Activation and Metabolism in Humans
Hachemi I, U-Din M |
Endocrinology and Metabolism | 2023 |
|
Revisiting adipose thermogenesis for delaying aging and age-related diseases: Opportunities and challenges
Tarantini S, Subramanian M, Butcher JT, Yabluchanskiy A, Li X, Miller RA, Balasubramanian P |
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|
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Schirinzi V, Poli C, Berteotti C, Leone A |
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|
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Fang R, Yan L, Liao Z |
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|
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KIM S, PARK DH, LEE SH, KWAK HB, KANG JH |
Medicine and science in sports and exercise | 2023 |
|
The emerging role of circadian rhythms in the development and function of thermogenic fat.
Peng X, Chen Y |
Frontiers in Endocrinology | 2023 |
|
Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice.
Park A, Kim KE, Park I, Lee SH, Park KY, Jung M, Li X, Sleiman MB, Lee SJ, Kim DS, Kim J, Lim DS, Woo EJ, Lee EW, Han BS, Oh KJ, Lee SC, Auwerx J, Mun JY, Rhee HW, Kim WK, Bae KH, Suh JM |
Nature Communications | 2023 |
|
Thermogenic Brown Fat in Humans: Implications in Energy Homeostasis, Obesity and Metabolic Disorders
Saito M, Okamatsu-Ogura Y |
The World Journal of Men's Health | 2023 |
|
Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice
Laiglesia LM, Escoté X, Sáinz N, Felix-Soriano E, Santamaría E, Collantes M, Fernández-Galilea M, Colón-Mesa I, Martínez-Fernández L, Quesada-López T, Quesada-Vázquez S, Rodríguez-Ortigosa C, Arbones-Mainar JM, Valverde ÁM, Martínez JA, Dalli J, Herrero L, Lorente-Cebrián S, Villarroya F, Moreno-Aliaga MJ |
Molecular Metabolism | 2023 |
|
Molecular and cellular regulation of thermogenic fat
Wang C, Wang X, Hu W |
Frontiers in Endocrinology | 2023 |
|
Opportunities and challenges: interleukin-22 comprehensively regulates polycystic ovary syndrome from metabolic and immune aspects.
Geng Y, Liu Z, Hu R, Ma W, Wu X, Dong H, Song K, Xu X, Huang Y, Li F, Song Y, Zhang M |
Journal of Ovarian Research | 2023 |
|
The serotonin transporter sustains human brown adipose tissue thermogenesis.
Suchacki KJ, Ramage LE, Kwok TC, Kelman A, McNeill BT, Rodney S, Keegan M, Gray C, MacNaught G, Patel D, Fletcher AM, Simpson JP, Carter RN, Semple RK, Homer NZM, Morton NM, van Beek EJR, Wakelin SJ, Stimson RH |
Nature metabolism | 2023 |
|
Fucoxanthin, a Functional Food Ingredient: Challenges in Bioavailability.
Fernandes V, Mamatha BS |
Current Nutrition Reports | 2023 |
|
Skeletal muscles and gut microbiota-derived metabolites: novel modulators of adipocyte thermogenesis
Tang Y, Wang YD, Wang YY, Liao ZZ, Xiao XH |
Frontiers in Endocrinology | 2023 |
|
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Taheri F, Hosseinzadeh-Attar MJ, Alipoor E, Honarkar-Shafie E, Yaseri M, Vasheghani-Farahani A |
The Journal of Tehran University Heart Center | 2023 |
|
The Effects of Intermittent Cold Exposure on Adipose Tissue.
Scott MC, Fuller S |
International journal of molecular sciences | 2023 |
|
Comprehensive Quantification of Metabolic Flux During Acute Cold Stress In Mice
Bornstein MR, Neinast MD, Zeng X, Chu Q, Axsom J, Thorsheim C, Li K, Blair MC, Rabinowitz JD, Arany Z |
Cell Metabolism | 2023 |
|
Neurohormonal Changes in the Gut–Brain Axis and Underlying Neuroendocrine Mechanisms following Bariatric Surgery
E Martinou, I Stefanova, E Iosif, A Angelidi |
International journal of molecular sciences | 2022 |
|
Mitophagy Mediates the Beige to White Transition of Human Primary Subcutaneous Adipocytes Ex Vivo
A Vámos, A Shaw, K Varga, I Csomós, G Mocsár, Z Balajthy, C Lányi, Z Bacso, M Szatmári-Tóth, E Kristóf |
Pharmaceuticals (Basel, Switzerland) | 2022 |
|
UCP1 Knockin Induces Lipid Dynamics and Transcriptional Programs in the Skeletal Muscles of Pigs
Ziye Xu, Wentao Chen, Liyi Wang, Wenjing You, Yanfang Wang, Yizhen Wang, Jianguo Zhao, Tizhong Shan |
Frontiers in Cell and Developmental Biology | 2022 |
|
Brown Adipose Tissue: Methods and Protocols
D Guertin, C Wolfrum |
2022 | |
|
ChREBP-regulated lipogenesis is not required for the thermogenesis of brown adipose tissue
C Wei, P Wang, Q Dong, X Ma, M Lu, S Qi, J Shi, Z Xie, A Ren, W Zhang |
International Journal of Obesity | 2022 |
|
The involvement of the adrenergic nervous system in activating human brown adipose tissue and browning
Y Pinto, W Festuccia, J Magdalon |
Hormones (Athens, Greece) | 2022 |
|
PET/MRI-evaluated brown adipose tissue activity may be related to dietary MUFA and omega-6 fatty acids intake
K Maliszewska, E Adamska-Patruno, K Miniewska, W Bauer, M Mojsak, A Kretowski |
Scientific Reports | 2022 |
|
Differing impact of phosphoglycerate mutase 1-deficiency on brown and white adipose tissue
Y Yoshida, I Shimizu, Y Hsiao, M Suda, G Katsuumi, M Seki, Y Suzuki, S Okuda, T Soga, T Minamino |
iScience | 2022 |
|
Brown Adipose Tissue Prevalence Is Lower in Obesity but Its Metabolic Activity Is Intact
O Kulterer, C Herz, M Prager, C Schmöltzer, F Langer, G Prager, R Marculescu, A Kautzky-Willer, M Hacker, A Haug, F Kiefer |
Frontiers in Endocrinology | 2022 |
|
Many Ways to Rome: Exercise, Cold Exposure and Diet—Do They All Affect BAT Activation and WAT Browning in the Same Manner?
A Scheel, L Espelage, A Chadt |
International journal of molecular sciences | 2022 |
|
Cold-Induced Thermogenesis Shows a Diurnal Variation That Unfolds Differently in Males and Females
M Straat, B Martinez-Tellez, A Mishre, M Verkleij, M Kemmeren, I Pelsma, J Alcantara, A Mendez-Gutierrez, S Kooijman, M Boon, P Rensen |
The Journal of clinical endocrinology and metabolism | 2022 |
|
Brown adipose tissue activation is not related to hypermetabolism in emphysematous chronic obstructive pulmonary disease patients
K Sanders, R Wierts, W Lichtenbelt, J VosGeelen, G Plasqui, M Kelders, V SchrauwenHinderling, J Bucerius, A Dingemans, F Mottaghy, A Schols |
Journal of Cachexia, Sarcopenia and Muscle | 2022 |
|
Paracrine Role of the Endothelium in Metabolic Homeostasis in Health and Nutrient Excess
C Luk, N Haywood, K Bridge, M Kearney |
Frontiers in Cardiovascular Medicine | 2022 |
|
Insight Into Rho Kinase Isoforms in Obesity and Energy Homeostasis
Wei L, Shi J |
Frontiers in Endocrinology | 2022 |
|
Metformin and vitamin D modulate adipose-derived stem cell differentiation towards the beige phenotype
Cruciani S, Garroni G, Pala R, Coradduzza D, Cossu ML, Ginesu GC, Capobianco G, Dessole S, Ventura C, Maioli M |
Adipocyte | 2022 |
|
Hypothalamic Estrogen Signaling and Adipose Tissue Metabolism in Energy Homeostasis
Torres Irizarry VC, Jiang Y, He Y, Xu P |
Frontiers in Endocrinology | 2022 |
|
Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity
Hayashi Y, Shimizu I, Yoshida Y, Ikegami R, Suda M, Katsuumi G, Fujiki S, Ozaki K, Abe M, Sakimura K, Okuda S, Hayano T, Nakamura K, Walsh K, Jespersen NZ, Nielsen S, Scheele C, Minamino T |
iScience | 2022 |
|
Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation.
Sugimoto S, Mena HA, Sansbury BE, Kobayashi S, Tsuji T, Wang CH, Yin X, Huang TL, Kusuyama J, Kodani SD, Darcy J, Profeta G, Pereira N, Tanzi RE, Zhang C, Serwold T, Kokkotou E, Goodyear LJ, Cypess AM, Leiria LO, Spite M, Tseng YH |
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|
Adipose tissue aging: mechanisms and therapeutic implications
Ou MY, Zhang H, Tan PC, Zhou SB, Li QF |
Cell Death and Disease | 2022 |
|
Capsaicin directly promotes adipocyte browning in the chemical compound-induced brown adipocytes converted from human dermal fibroblasts
Takeda Y, Dai P |
Scientific Reports | 2022 |
|
Dysfunction of insulin-AKT-UCP1 signalling inhibits transdifferentiation of human and mouse white preadipocytes into brown-like adipocytes
Pan J, Kothan S, Moe Moe AT, Huang K |
Adipocyte | 2022 |
|
The Role of Thermogenic Fat Tissue in Energy Consumption
Horino M, Ikeda K, Yamada T |
Current issues in molecular biology | 2022 |
|
The Heartwarming Effect of Brown Adipose Tissue
Pinckard KM, Stanford KI |
Molecular pharmacology | 2022 |
|
Calcium Cycling as a Mediator of Thermogenic Metabolism in Adipose Tissue
Guarnieri AR, Benson TW, Tranter M |
Molecular pharmacology | 2022 |
|
Interactions between central nervous system and peripheral metabolic organs.
Zeng W, Yang F, Shen WL, Zhan C, Zheng P, Hu J |
Science China Life Sciences | 2022 |
|
Effect of Acute Cold Exposure on Energy Metabolism and Activity of Brown Adipose Tissue in Humans: A Systematic Review and Meta-Analysis.
Huo C, Song Z, Yin J, Zhu Y, Miao X, Qian H, Wang J, Ye L, Zhou L |
Frontiers in physiology | 2022 |
|
Effects of ambient temperatures between 5 and 35 °C on energy balance, body mass and body composition in mice.
Zhao Z, Yang R, Li M, Bao M, Huo D, Cao J, Speakman JR |
Molecular Metabolism | 2022 |
|
NFIA determines the cis-effect of genetic variation on Ucp1 expression in murinethermogenic adipocytes.
Hiraike Y, Tsutsumi S, Wada T, Oguchi M, Saito K, Nakamura M, Ota S, Koebis M, Nakao H, Aiba A, Nagano G, Ohno H, Oki K, Yoneda M, Kadowaki T, Aburatani H, Waki H, Yamauchi T |
iScience | 2022 |
|
The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation
Song Z, Xiaoli AM, Li Y, Siqin G, Wu T, Strich R, Pessin JE, Yang F |
Molecular Metabolism | 2022 |
|
Evaluation of thermal sensitivity is of potential clinical utility for the predictive, preventive, and personalized approach advancing metabolic syndrome management
Mun S, Park K, Lee S |
The EPMA Journal | 2022 |
|
The Effects of 10-Week Strength Training in the Winter on Brown-like Adipose Tissue Vascular Density
Tanaka R, Fuse-Hamaoka S, Kuroiwa M, Kurosawa Y, Endo T, Kime R, Yoneshiro T, Hamaoka T |
International journal of environmental research and public health | 2022 |
|
Sex Differences in Adiposity and Cardiovascular Diseases
Li H, Konja D, Wang L, Wang Y |
International journal of molecular sciences | 2022 |
|
Comparative transcriptomic analysis of rabbit interscapular brown adipose tissue whitening under physiological conditions.
Li L, Wan Q, Long Q, Nie T, Zhao S, Mao L, Cheng C, Zou C, Loomes K, Xu A, Lai L, Liu X, Duan Z, Hui X, Wu D |
Adipocyte | 2022 |
|
The evolving view of thermogenic fat and its implications in cancer and metabolic diseases.
Yin X, Chen Y, Ruze R, Xu R, Song J, Wang C, Xu Q |
Signal Transduction and Targeted Therapy | 2022 |
|
Metabolomics reveals inosine 5′-monophosphate is increased during mice adipocyte browning
Takahashi H, Tokura M, Kawarasaki S, Nagai H, Iwase M, Nishitani K, Okaze H, Mohri S, Ito T, Ara T, Jheng HF, Nomura W, Kawada T, Inoue K, Goto T |
The Journal of biological chemistry | 2022 |
|
Spicy food consumption is associated with abdominal obesity among Chinese Han population aged 30–79 years in the Sichuan Basin: a population-based cross-sectional study
Yang X, Tang W, Mao D, Liu X, Qian W, Dai Y, Chen L, Ding X |
BMC Public Health | 2022 |
|
Aging attenuates diurnal lipid uptake by brown adipose tissue.
In Het Panhuis W, Schönke M, Siebeler R, Afkir S, Baelde R, Pronk ACM, Streefland TCM, Sips HCM, Lalai RA, Rensen PCN, Kooijman S |
Aging | 2022 |
|
Mass Spectrometry-Based Lipidomics of Brown Adipose Tissue and Plasma of New-Born Lambs Subjected to Short-Term Cold Exposure.
Graña-Baumgartner A, Dukkipati VSR, Biggs PJ, Kenyon PR, Blair HT, López-Villalobos N, Ross AB |
2022 | |
|
Endothelial SIRT-1 has a critical role in the maintenance of capillarization in brown adipose tissue
Furuuchi R, Shimizu I, Yoshida Y, Katsuumi G, Suda M, Kubota Y, Walsh K, Minamino T |
iScience | 2022 |
|
Cooling down with Entresto. Can sacubitril/valsartan combination enhance browning more than coldness?
Nikolic M, Novakovic J, Ramenskaya G, Kokorekin V, Jeremic N, Jakovljevic V |
Diabetology & metabolic syndrome | 2022 |
|
MicroRNAs as Mediators of Adipose Thermogenesis and Potential Therapeutic Targets for Obesity.
Ma L, Gilani A, Yi Q, Tang L |
Biology | 2022 |
|
Naringenin, a citrus flavanone, enhances browning and brown adipogenesis: Role of peroxisome proliferator-activated receptor gamma.
Bae J, Yang Y, Xu X, Flaherty J, Overby H, Hildreth K, Chen J, Wang S, Zhao L |
Frontiers in Nutrition | 2022 |
|
Adipose Tissue Dysfunction in Obesity: Role of Mineralocorticoid Receptor
Parasiliti-Caprino M, Bollati M, Merlo FD, Ghigo E, Maccario M, Bo S |
Nutrients | 2022 |
|
Interventions associated with brown adipose tissue activation and the impact on energy expenditure and weight loss: A systematic review
Perez LC, Perez LT, Nene Y, Umpierrez GE, Davis GM, Pasquel FJ |
Frontiers in Endocrinology | 2022 |
|
Chronic Intermittent Hypoxia during Sleep Causes Browning of Interscapular Adipose Tissue Accompanied by Local Insulin Resistance in Mice
Dahan T, Nassar S, Yajuk O, Steinberg E, Benny O, Abudi N, Plaschkes I, Benyamini H, Gozal D, Abramovitch R, Gileles-Hillel A |
International journal of molecular sciences | 2022 |
|
Brown Adipose Tissue—A Translational Perspective
Carpentier AC, Blondin DP, Haman F, Richard D |
Endocrine reviews | 2022 |
|
Brown adipose tissue and regulation of human body weight.
Harb E, Kheder O, Poopalasingam G, Rashid R, Srinivasan A, Izzi-Engbeaya C |
Diabetes/Metabolism Research and Reviews | 2022 |
|
Role of thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans
Ying Z, Tramper N, Zhou E, Boon MR, Rensen PC, Kooijman S |
Cardiovascular Research | 2022 |
|
Activating Human Adipose Tissue with the β3-Adrenergic Agonist Mirabegron.
Chen KY, Brychta RJ, Israni NS, Jiang A, Lea HJ, Lentz TN, Pierce AE, Cypess AM |
Methods in molecular biology (Clifton, N.J.) | 2022 |
|
CMKLR1 senses chemerin/resolvin E1 to control adipose thermogenesis and modulate metabolic homeostasis
Zhao Z, Liu S, Qian B, Zhou L, Shi J, Liu J, Xu L, Yang Z |
Fundamental Research | 2022 |
|
Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism
Brian S. Finlin, Hasiyet Memetimin, Beibei Zhu, Amy L Confides, Hemendra J. Vekaria, Riham H. El Khouli, Zachary R. Johnson, Philip M. Westgate, Jianzhong Chen, Andrew J. Morris, Patrick G. Sullivan, Esther E Dupont-Versteegden, Philip A. Kern |
JCI Insight | 2021 |
|
Contrasting recruitment of skin‐associated adipose depots during cold challenge of mouse and human
I Kasza, JP Kühn, H Völzke, D Hernando, YG Xu, JW Siebert, AL Gibson, CL Yen, DW Nelson, OA MacDougald, NE Richardson, DW Lamming, PA Kern, CM Alexander |
The Journal of Physiology | 2021 |
|
Beige fat is dispensable for the metabolic benefits associated with myostatin deletion
F Marchildon, J Chi, S O'Connor, H Bediako, P Cohen |
Molecular Metabolism | 2021 |
|
MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging
MS Afonso, N Verma, C van Solingen, Y Cyr, M Sharma, L Perie, EM Corr, M Schlegel, LC Shanley, D Peled, JY Yoo, AM Schmidt, E Mueller, KJ Moore |
Arteriosclerosis, thrombosis, and vascular biology | 2021 |
|
Thermogenic Fat: Development, Physiological Function, and Therapeutic Potential
BB Brandão, A Poojari, A Rabiee |
International journal of molecular sciences | 2021 |
|
Intercellular and inter-organ crosstalk in browning of white adipose tissue: molecular mechanism and therapeutic complications
LY Cheong, A Xu, WP Jia |
Journal of Molecular Cell Biology | 2021 |
|
miRNA-22 deletion limits white adipose expansion and activates brown fat to attenuate high-fat diet-induced fat mass accumulation
VM Lima, J Liu, BB Brandão, CA Lino, CS Silva, MA Ribeiro, TE Oliveira, CC Real, D de Paula Faria, C Cederquist, ZP Huang, X Hu, ML Barreto-Chaves, JC Ferreira, WT Festuccia, MA Mori, CR Kahn, DZ Wang, GP Diniz |
Metabolism | 2021 |
|
MECHANISMS IN ENDOCRINOLOGY: Human brown adipose tissue as a therapeutic target: warming up or cooling down?
BT McNeill, KJ Suchacki, RH Stimson |
European Journal of Endocrinology | 2021 |
|
Brown Adipose Tissue and Its Role in Insulin and Glucose Homeostasis
K Maliszewska, A Kretowski |
International journal of molecular sciences | 2021 |
|
The cellular and functional complexity of thermogenic fat
P Cohen, S Kajimura |
Nature Reviews Molecular Cell Biology | 2021 |
|
Brown Adipose Tissue Heterogeneity, Energy Metabolism, and Beyond
AB Shinde, A Song, QA Wang |
Frontiers in Endocrinology | 2021 |
|
Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic
Y Zekri, F Flamant, K Gauthier |
Cells | 2021 |
|
Free Thyroxine Levels are Associated with Cold Induced Thermogenesis in Healthy Euthyroid Individuals
CI Maushart, JR Senn, RC Loeliger, ME Kraenzlin, J Müller, AS Becker, M Balaz, C Wolfrum, IA Burger, MJ Betz |
Frontiers in Endocrinology | 2021 |
|
Obesity, Adipose Tissue and Vascular Dysfunction
M Koenen, MA Hill, P Cohen, JR Sowers |
Circulation research | 2021 |
|
Obesity–An Update on the Basic Pathophysiology and Review of Recent Therapeutic Advances
E Gjermeni, AS Kirstein, F Kolbig, M Kirchhof, L Bundalian, JL Katzmann, U Laufs, M Blüher, A Garten, DL Duc |
Biomolecules | 2021 |
|
Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance
VI Gallardo-Montejano, C Yang, L Hahner, JL McAfee, JA Johnson, WL Holland, R Fernandez-Valdivia, PE Bickel |
Nature Communications | 2021 |
|
Browning white adipose tissue using adipose stromal cell-targeted resveratrol-loaded nanoparticles for combating obesity
Y Zu, L Zhao, L Hao, Y Mechref, M Zabet-Moghaddam, PA Keyel, M Abbasi, D Wu, JA Dawson, R Zhang, S Nie, N Moustaid-Moussa, MG Kolonin, AC Daquinag, L Brandi, I Warraich, SK Francisco, X Sun, Z Fan, S Wang |
Journal of Controlled Release | 2021 |
|
Immune and non-immune functions of adipose tissue leukocytes
WV Trim, L Lynch |
Nature Reviews Immunology | 2021 |
|
Progranulin: A proangiogenic factor in visceral adipose tissue in tumoral and non‑tumoral visceral pathology
I Binișor, I Baniță, D Alexandru, M Mehedinți, S Jurja, AM Andrei, C Pisoschi |
Experimental and therapeutic medicine | 2021 |
|
Obeticholic acid ameliorates obesity and hepatic steatosis by activating brown fat
H Zhang, M Dong, X Liu |
Experimental and therapeutic medicine | 2021 |
|
Nutritional Regulation of Human Brown Adipose Tissue
KJ Suchacki, RH Stimson |
Nutrients | 2021 |
|
Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and -independent mechanisms
J Sostre-Colón, K Uehara, AE Whitlock, MJ Gavin, J Ishibashi, MJ Potthoff, P Seale, PM Titchenell |
Cell Reports | 2021 |
|
Endotoxemia by Porphyromonas gingivalis Alters Endocrine Functions in Brown Adipose Tissue
M Hatasa, Y Ohsugi, S Katagiri, S Yoshida, H Niimi, K Morita, Y Tsuchiya, T Shimohira, N Sasaki, S Maekawa, T Shiba, T Hirota, H Tohara, H Takahashi, H Nitta, T Iwata |
Frontiers in Cellular and Infection Microbiology | 2021 |
|
Overexpression of Adiponectin Receptor 1 Inhibits Brown and Beige Adipose Tissue Activity in Mice
YJ Chen, CW Lin, YJ Peng, CW Huang, YS Chien, TH Huang, PX Liao, WY Yang, MH Wang, HJ Mersmann, SC Wu, TY Chuang, YY Lin, WH Kuo, ST Ding |
International journal of molecular sciences | 2021 |
|
Partial-Body Cryostimulation Increases Resting Energy Expenditure in Lean and Obese Women
MD Nardi, A Bisio, LD Guardia, C Facheris, E Faelli, AL Torre, L Luzi, P Ruggeri, R Codella |
International journal of environmental research and public health | 2021 |
|
Reduced brown adipose tissue activity during cold exposure is a metabolic feature of the human thrifty phenotype
T Hollstein, K Vinales, KY Chen, AM Cypess, A Basolo, M Schlögl, J Krakoff, P Piaggi |
Metabolism | 2021 |
|
Brown Adipose Tissue Activation by Cold Treatment Ameliorates Polycystic Ovary Syndrome in Rat
R Ye, C Yan, H Zhou, Y Huang, M Dong, H Zhang, X Jiang, S Yuan, L Chen, R Jiang, Z Cheng, K Zheng, Q Zhang, W Jin |
Frontiers in Endocrinology | 2021 |
|
Human Brown Adipose Tissue and Metabolic Health: Potential for Therapeutic Avenues
R Singh, A Barrios, G Dirakvand, S Pervin |
Cells | 2021 |
|
Defective insulin-stimulated GLUT4 translocation in brown adipocytes induces systemic glucose homeostasis dysregulation independent of thermogenesis in female mice
B Picatoste, L Yammine, RA Leahey, D Soares, EF Johnson, P Cohen, TE McGraw |
Molecular Metabolism | 2021 |
|
TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
F Sass, C Schlein, MY Jaeckstein, P Pertzborn, M Schweizer, T Schinke, A Ballabio, L Scheja, J Heeren, AW Fischer |
Molecular Metabolism | 2021 |
|
STK3/STK4 signalling in adipocytes regulates mitophagy and energy expenditure
Y Cho, Y Son, A Saha, D Kim, C Choi, M Kim, J Park, H Im, J Han, K Kim, Y Jung, J Yun, E Bae, J Seong, M Lee, S Lee, J Granneman, Y Lee |
Nature metabolism | 2021 |
|
The impact of catecholamines on skeletal muscle following massive burns: Friend or foe?
E Blears, E Ross, JO Ogunbileje, C Porter, AJ Murton |
Burns : journal of the International Society for Burn Injuries | 2021 |
|
Effects of Caffeine on Brown Adipose Tissue Thermogenesis and Metabolic Homeostasis: A Review
LV Schaik, C Kettle, R Green, HR Irving, JA Rathner |
Frontiers in neuroscience | 2021 |
|
Fish Oil Increases Diet-Induced Thermogenesis in Mice
T Yamazaki, D Li, R Ikaga |
Marine drugs | 2021 |
|
Metabolic responses to mild cold acclimation in type 2 diabetes patients
CM Remie, MP Moonen, KH Roumans, EB Nascimento, A Gemmink, B Havekes, G Schaart, E Kornips, PJ Joris, VB Schrauwen-Hinderling, J Hoeks, S Kersten, MK Hesselink, E Phielix, WD van Marken Lichtenbelt, P Schrauwen |
Nature Communications | 2021 |
|
Progenitor-like characteristics in a subgroup of UCP1+ cells within white adipose tissue
J Park, S Shin, L Liu, I Jahan, SG Ong, P Xu, DC Berry, Y Jiang |
Developmental Cell | 2021 |
|
Human Brown Adipose Tissue—A Decade Later
WD Lichtenbelt |
Obesity | 2021 |
|
AKAP1 Deficiency Attenuates Diet‐Induced Obesity and Insulin Resistance by Promoting Fatty Acid Oxidation and Thermogenesis in Brown Adipocytes
L Ji, Y Zhao, L He, J Zhao, T Gao, F Liu, B Qi, F Kang, G Wang, Y Zhao, H Guo, Y He, F Li, Q Huang, J Xing |
Advanced Science | 2021 |
|
Diurnal variations of brown fat thermogenesis and fat oxidation in humans
M Matsushita, S Nirengi, M Hibi, H Wakabayashi, S Lee, M Domichi, N Sakane, M Saito |
International Journal of Obesity | 2021 |
|
Natural Extracts That Stimulate Adipocyte Browning and Their Underlying Mechanisms
MK Lee, B Lee, CY Kim |
Antioxidants | 2021 |
|
Physical Activity Attenuates the Obesity-Induced Dysregulated Expression of Brown Adipokines in Murine Interscapular Brown Adipose Tissue
T Sakurai, T Fukutomi, S Yamamoto, E Nozaki, T Kizaki |
International journal of molecular sciences | 2021 |
|
Brown adipose tissue is associated with cardiometabolic health
T Becher, S Palanisamy, DJ Kramer, M Eljalby, SJ Marx, AG Wibmer, SD Butler, CS Jiang, R Vaughan, H Schöder, A Mark, P Cohen |
Nature Medicine | 2021 |
|
Evaluation of Browning Agents on the White Adipogenesis of Bone Marrow Mesenchymal Stromal Cells: A Contribution to Fighting Obesity
GD Maio, N Alessio, IH Demirsoy, G Peluso, S Perrotta, M Monda, GD Bernardo |
Cells | 2021 |
|
Berberine modulates deacetylation of PPARγ to promote adipose tissue remodeling and thermogenesis via AMPK/SIRT1 pathway
Y Xu, T Yu, G Ma, L Zheng, X Jiang, F Yang, Z Wang, N Li, Z He, X Song, D Wen, J Kong, Y Yu, L Cao |
International journal of biological sciences | 2021 |
|
Defining the lineage of thermogenic perivascular adipose tissue
AR Angueira, AP Sakers, CD Holman, L Cheng, MN Arbocco, F Shamsi, MD Lynes, R Shrestha, C Okada, K Batmanov, K Susztak, YH Tseng, L Liaw, P Seale |
Nature metabolism | 2021 |
|
Adipose Tissue and Cancer Cachexia: What Nurses Need to Know
Susan Mcclement |
Asia-Pacific Journal of Oncology Nursing | 2021 |
|
Brown Fat as a Regulator of Systemic Metabolism beyond Thermogenesis
OO Yuko, M Saito |
Diabetes & Metabolism Journal | 2021 |
|
Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat
F Li, J Jing, M Movahed, X Cui, Q Cao, R Wu, Z Chen, L Yu, Y Pan, H Shi, H Shi, B Xue |
Nature Communications | 2021 |
|
The genesis of brown fat—a smooth muscle origin story revisited
A Deutsch, K Shinoda |
Nature metabolism | 2021 |
|
Influences of ovarian hormones on physiological responses to cold in women
Greenfield AM, Charkoudian N, Alba BK |
2021 | |
|
The effects of a novel personal comfort system on thermal comfort, physiology and perceived indoor environmental quality, and its health implications - Stimulating human thermoregulation without compromising thermal comfort.
Luo W, Kramer R, de Kort Y, Rense P, van Marken Lichtenbelt W |
Indoor Air | 2021 |
|
Caenorhabditis elegans as a model organism in obesity research
Dyczkowska AA, Chabowska-Kita A |
2021 | |
|
Obesity, Body Composition, and Sex Hormones: Implications for Cardiovascular Risk
Singh P, Covassin N, Marlatt K, Gadde KM, Heymsfield SB |
Comprehensive Physiology | 2021 |
|
Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity
Alana E O'Mara, James W Johnson, Joyce D. Linderman, Robert J. Brychta, Suzanne McGehee, Laura A. Fletcher, Yael Fink, Devika Kapuria, Thomas M Cassimatis, Nathan Kelsey, Cheryl Cero, Zahraa Abdul Sater, Francesca Piccinini, Alison S. Baskin, Brooks P Leitner, Hongyi Cai, Corina M. Millo, William Dieckmann, Mary Walter, Norman B. Javitt, Yaron Rotman, Peter J Walter, Marilyn Ader, Richard N. Bergman, Peter Herscovitch, Kong Y. Chen, Aaron M Cypess |
Journal of Clinical Investigation | 2020 |
|
The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans
Brian S. Finlin, Hasiyet Memetimin, Beibei Zhu, Amy L. Confides, Hemendra J. Vekaria, Riham H. El Khouli, Zachary R. Johnson, Philip M. Westgate, Jianzhong Chen, Andrew J. Morris, Patrick G. Sullivan, Esther E. Dupont-Versteegden, Philip A. Kern |
Journal of Clinical Investigation | 2020 |
|
Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure
Wei Zou, Nidhi Rohatgi, Jonathan R. Brestoff, John R. Moley, Yongjia Li, Jesse W. Williams, Yael Alippe, Hua Pan, Terri A. Pietka, Gabriel Mbalaviele, Elizabeth P. Newberry, Nicholas O. Davidson, Anwesha Dey, Kooresh I. Shoghi, Richard D. Head, Samuel A. Wickline, Gwendalyn J. Randolph, Nada A. Abumrad, Steven L. Teitelbaum |
Journal of Clinical Investigation | 2020 |
|
The omentum of obese girls harbors small adipocytes and browning transcripts
Elena Tarabra, Jessica Nouws, Alla Vash-Margita, Geoffrey S. Nadzam, Rachel Goldberg-Gell, Michelle Van Name, Bridget Pierpont, James Knight, Gerald I. Shulman, Sonia Caprio |
JCI Insight | 2020 |
|
Exercise‐induced α‐ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1‐dependent adrenal activation
Y Yuan, P Xu, Q Jiang, X Cai, T Wang, W Peng, J Sun, C Zhu, C Zhang, D Yue, Z He, J Yang, Y Zeng, M Du, F Zhang, L Ibrahimi, S Schaul, Y Jiang, J Wang, J Sun, Q Wang, L Liu, S Wang, L Wang, X Zhu, P Gao, , C Yin, F Li, G Xu, Y Zhang, G Shu |
The EMBO Journal | 2020 |
|
Effects of beta-conglycinin intake on circulating FGF21 levels and brown adipose tissue activity in Japanese young men: a single intake study and a randomized controlled trial
H Taniguchi, K Shimizu, S Wada, S Nirengi, H Kataoka, A Higashi |
Journal of PHYSIOLOGICAL ANTHROPOLOGY | 2020 |
|
Circadian Rhythm in Adipose Tissue: Novel Antioxidant Target for Metabolic and Cardiovascular Diseases
AW Man, N Xia, H Li |
Antioxidants | 2020 |
|
Control of Adipose Cell Browning and Its Therapeutic Potential
F Lizcano, F Arroyave |
Metabolites | 2020 |
|
Overheating or overcooling: heat transfer in the spot to fight against the pandemic obesity
LH Manfredi |
Reviews in Endocrine and Metabolic Disorders | 2020 |
|
Advances in cancer cachexia: Intersections between affected organs, mediators, and pharmacological interventions
JA Siddiqui, R Pothuraju, M Jain, SK Batra, MW Nasser |
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer | 2020 |
|
Incendiary Leptin
P Seoane-Collazo, N Martínez-Sánchez, E Milbank, C Contreras |
Nutrients | 2020 |
|
TSH promotes adiposity by inhibiting the browning of white fat
J Zhang, H Wu, S Ma, L Gao, C Yu, F Jing, J Zhao |
Adipocyte | 2020 |
|
Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease
A Chait, LJ den Hartigh |
Frontiers in Cardiovascular Medicine | 2020 |
|
Adipose stem cells in obesity: challenges and opportunities
S Shin, AS El-Sabbagh, BE Lukas, SJ Tanneberger, Y Jiang |
Bioscience Reports | 2020 |
|
HuR expression in adipose tissue mediates energy expenditure and acute thermogenesis independent of UCP1 expression
SR Anthony, A Guarnieri, L Lanzillotta, A Gozdiff, LC Green, K OGrady, RN Helsley, AP Owens, M Tranter |
Adipocyte | 2020 |
|
The Effect of FOXC2-AS1 on White Adipocyte Browning and the Possible Regulatory Mechanism
Y Wang, S Hua, X Cui, Y Cao, J Wen, X Chi, C Ji, LX Pang, L You |
Frontiers in Endocrinology | 2020 |
|
Do Bariatric Surgeries Enhance Brown/Beige Adipose Tissue Thermogenesis?
MK Hankir, F Seyfried |
Frontiers in Endocrinology | 2020 |
|
Induction of Adipose Tissue Browning as a Strategy to Combat Obesity
A Kuryłowicz, M Puzianowska-Kuźnicka |
International journal of molecular sciences | 2020 |
|
Brown Adipose Tissue, Diet-Induced Thermogenesis, and Thermogenic Food Ingredients: From Mice to Men
M Saito, M Matsushita, T Yoneshiro, Y Okamatsu-Ogura |
Frontiers in Endocrinology | 2020 |
|
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation
K Fischer, A Fenzl, D Liu, KA Dyar, M Kleinert, M Brielmeier, C Clemmensen, A Fedl, B Finan, A Gessner, M Jastroch, J Huang, S Keipert, M Klingenspor, JC Brüning, M Kneilling, FC Maier, AE Othman, BJ Pichler, I Pramme-Steinwachs, S Sachs, A Scheideler, WM Thaiss, H Uhlenhaut, S Ussar, SC Woods, J Zorn, K Stemmer, S Collins, M Diaz-Meco, J Moscat, MH Tschöp, TD Müller |
Nature Communications | 2020 |
|
Magnetic Resonance Imaging Techniques for Brown Adipose Tissue Detection
M Wu, D Junker, RT Branca, DC Karampinos |
Frontiers in Endocrinology | 2020 |
|
Rhubarb Supplementation Prevents Diet-Induced Obesity and Diabetes in Association with Increased Akkermansia muciniphila in Mice
M Régnier, M Rastelli, A Morissette, F Suriano, TL Roy, G Pilon, NM Delzenne, A Marette, MV Hul, PD Cani |
Nutrients | 2020 |
|
Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice
AW Fischer, J Behrens, F Sass, C Schlein, M Heine, P Pertzborn, L Scheja, J Heeren |
Journal of lipid research | 2020 |
|
Biomarkers of Browning in Cold Exposed Siberian Adults
A Efremova, G Colleluori, M Thomsky, J Perugini, M Protasoni, M Reguzzoni, A Faragalli, F Carle, A Giordano, S Cinti |
Nutrients | 2020 |
|
The effect of mirabegron on energy expenditure and brown adipose tissue in healthy lean South Asian and Europid men
KJ Nahon, LG Janssen, AS Mishre, MP Bilsen, JA Eijk, K Botani, LA Overduin, JR Ruiz, J Burakiewicz, O Dzyubachyk, AG Webb, HE Kan, JF Berbée, JB Klinken, KW Dijk, M Weeghel, FM Vaz, T Coskun, IM Jazet, S Kooijman, B MartinezTellez, MR Boon, PC Rensen |
Diabetes, obesity & metabolism | 2020 |
|
Effects of Nutrition/Diet on Brown Adipose Tissue in Humans: A Systematic Review and Meta-Analysis
KA Heenan, AE Carrillo, JL Fulton, EJ Ryan, JR Edsall, D Rigopoulos, MM Markofski, AD Flouris, PC Dinas |
Nutrients | 2020 |
|
Loss of Uncoupling Protein 3 Attenuates Western Diet–Induced Obesity, Systemic Inflammation, and Insulin Resistance in Rats
TM Lomax, S Ashraf, G Yilmaz, R Harmancey |
Obesity | 2020 |
|
Prevalence and Associated Factor of Brown Adipose Tissue: Systematic Review and Meta-Analysis
MG Worku, WS Seretew, DA Angaw, GA Tesema |
BioMed Research International | 2020 |
|
Studying Brown Adipose Tissue in a Human in vitro Context
I Samuelson, A Vidal-Puig |
Frontiers in Endocrinology | 2020 |
|
Vigorous-Intensity Physical Activities Are Associated with High Brown Adipose Tissue Density in Humans
R Tanaka, S Fuse, M Kuroiwa, S Amagasa, T Endo, A Ando, R Kime, Y Kurosawa, T Hamaoka |
International journal of environmental research and public health | 2020 |
|
An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models
MJ Choi, SB Jung, SE Lee, SG Kang, JH Lee, MJ Ryu, HK Chung, JY Chang, YK Kim, HJ Hong, H Kim, HJ Kim, CH Lee, A Mardinoglu, HS Yi, M Shong |
Diabetologia | 2020 |
|
Sesamol Increases Ucp1 Expression in White Adipose Tissues and Stimulates Energy Expenditure in High-Fat Diet-Fed Obese Mice
DH Lee, SH Chang, DK Yang, NJ Song, UJ Yun, KW Park |
Nutrients | 2020 |
|
CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling
Y Oguri, K Shinoda, H Kim, DL Alba, WR Bolus, Q Wang, Z Brown, RN Pradhan, K Tajima, T Yoneshiro, K Ikeda, Y Chen, RT Cheang, K Tsujino, CR Kim, VJ Greiner, R Datta, CD Yang, K Atabai, MT McManus, SK Koliwad, BM Spiegelman, S Kajimura |
Cell | 2020 |
|
Near-Infrared Time-Resolved Spectroscopy for Assessing Brown Adipose Tissue Density in Humans: A Review
T Hamaoka, S Nirengi, S Fuse, S Amagasa, R Kime, M Kuroiwa, T Endo, N Sakane, M Matsushita, M Saito, T Yoneshiro, Y Kurosawa |
Frontiers in Endocrinology | 2020 |
|
BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning
T Liu, L Mi, J Xiong, P Orchard, Q Yu, L Yu, XY Zhao, ZX Meng, SC Parker, JD Lin, S Li |
Nature Communications | 2020 |
|
The Transcriptional Role of Vitamin A and the Retinoid Axis in Brown Fat Function
CT Herz, FW Kiefer |
Frontiers in Endocrinology | 2020 |
|
UCP1 Dependent and Independent Thermogenesis in Brown and Beige Adipocytes
K Ikeda, T Yamada |
Frontiers in Endocrinology | 2020 |
|
Browning capabilities of human primary adipose-derived stromal cells compared to SGBS cells
D Halbgebauer, M Dahlhaus, M Wabitsch, P Fischer-Posovszky, D Tews |
Scientific Reports | 2020 |
|
Role of Brown Adipose Tissue in Adiposity Associated With Narcolepsy Type 1
ME Straat, MS Schinkelshoek, R Fronczek, GJ Lammers, PC Rensen, MR Boon |
Frontiers in Endocrinology | 2020 |
|
Berardinelli–Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing
H Zhou, C Xu, H Lee, Y Yoon, W Chen |
Molecular Metabolism | 2020 |
|
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
Y Wang, M Gao, F Zhu, X Li, Y Yang, Q Yan, L Jia, L Xie, Z Chen |
Nature Communications | 2020 |
|
Effects of Capsinoids on Daily Physical Activity, Body Composition and Cold Hypersensitivity in Middle-Aged and Older Adults: A Randomized Study
K Yokoyama, Y Yamada, Y Akamatsu, Y Yoshinaka, A Yamamoto, T Koizumi, K Ohyama, K Suzuki, M Hashimoto, H Sato, M Kimura |
Nutrients | 2020 |
|
Comparative analysis of restraint stress-induced depressive-like phenotypes in C57BL/6N mice derived from three different sources
DJ Hwang, KC Kwon, DY Hwang, MS Seo, KS Kim, YS Jung, JY Cho |
Laboratory animal research | 2020 |
|
Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis
A Fenzl, OC Kulterer, K Spirk, G Mitulović, R Marculescu, M Bilban, S Baumgartner-Parzer, A Kautzky-Willer, L Kenner, J Plutzky, L Quadro, FW Kiefer |
Molecular Metabolism | 2020 |
|
Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes
AR Angueira, SN Shapira, J Ishibashi, S Sampat, J Sostre-Colón, MJ Emmett, PM Titchenell, MA Lazar, HW Lim, P Seale |
Cell Reports | 2020 |
|
Relationships between plasma lipidomic profiles and brown adipose tissue density in humans
S Fuse, M Sugimoto, Y Kurosawa, M Kuroiwa, Y Aita, A Tomita, E Yamaguchi, R Tanaka, T Endo, R Kime, T Hamaoka |
International Journal of Obesity | 2020 |
|
Perivascular Adipose Tissue and Vascular Perturbation/Atherosclerosis
HW Kim, H Shi, MA Winkler, R Lee, NL Weintraub |
Arteriosclerosis, thrombosis, and vascular biology | 2020 |
|
Commentary on: “The Presence of Active Brown Adipose Tissue Determines Cold-Induced Energy Expenditure and Oxylipin Profiles in Humans”
MD Lynes, YH Tseng |
The Journal of clinical endocrinology and metabolism | 2020 |
|
Effects of Capsinoid Intake on Brown Adipose Tissue Vascular Density and Resting Energy Expenditure in Healthy, Middle-Aged Adults: A Randomized, Double-Blind, Placebo-Controlled Study
S Fuse, T Endo, R Tanaka, M Kuroiwa, A Ando, A Kume, A Yamamoto, K Kuribayashi, S Somekawa, M Takeshita, M Hashimoto, R Kime, Y Kurosawa, T Hamaoka |
Nutrients | 2020 |
|
Combined extracts of Moringa oleifera, Murraya koeingii leaves, and Curcuma longa rhizome increases energy expenditure and controls obesity in high-fat diet-fed rats
S Kundimi, KC Kavungala, S Sinha, VN Tayi, NR Kundurthi, T Golakoti, B Davis, K Sengupta |
Lipids in Health and Disease | 2020 |
|
Risk Analysis of Air Pollution and Meteorological Factors Affecting the Incidence of Diabetes in the Elderly Population in Northern China
Y Lin, S Zhou, H Liu, Z Cui, F Hou, S Feng, Y Zhang, H Liu, C Lu, P Yu, H Okamoto |
Journal of Diabetes Research | 2020 |
|
Isolation of Adipose Tissue Nuclei for Single-Cell Genomic Applications
GJ Benitez, K Shinoda |
Journal of visualized experiments : JoVE | 2020 |
|
Brown Fat Activation Mitigates Alcohol-induced Liver Steatosis and Injury in Mice
Hong Shen, Lin Jiang, Jiandie Lin, M. Bishr Omary, Liangyou Rui |
Journal of Clinical Investigation | 2019 |
|
The hepatokine Tsukushi gates energy expenditure via brown fat sympathetic innervation
Q Wang, VP Sharma, H Shen, Y Xiao, Q Zhu, X Xiong, L Guo, L Jiang, K Ohta, S Li, H Shi, L Rui, JD Lin |
2019 | |
|
Compensation for cold-induced thermogenesis during weight loss maintenance and regain
DM Presby, MR Jackman, MC Rudolph, VD Sherk, RM Foright, JA Houck, GC Johnson, DJ Orlicky, EL Melanson, JA Higgins, PS MacLean |
American journal of physiology. Endocrinology and metabolism | 2019 |
|
The Beige Adipocyte as a Therapy for Metabolic Diseases
F Lizcano |
International journal of molecular sciences | 2019 |
|
Brown fat organogenesis and maintenance requires AKT1 and AKT2
J Sanchez-Gurmaches, CM Calejman, SM Jung, H Li, DA Guertin |
Molecular Metabolism | 2019 |
|
Brown Adipose Crosstalk in Tissue Plasticity and Human Metabolism
C Scheele, C Wolfrum |
Endocrine reviews | 2019 |
|
Mechanisms of Impaired Brown Adipose Tissue Recruitment in Obesity
M Alcalá, M Calderon-Dominguez, D Serra, L Herrero, M Viana |
Frontiers in physiology | 2019 |
|
Zfp238 Regulates the Thermogenic Program in Cooperation with Foxo1
M Kita, J Nakae, Y Kawano, H Asahara, H Takemori, H Okado, H Itoh |
iScience | 2019 |
|
Opportunities and challenges in the therapeutic activation of human energy expenditure and thermogenesis to manage obesity
KY Chen, RJ Brychta, ZA Sater, TM Cassimatis, C Cero, LA Fletcher, NS Israni, JW Johnson, HJ Lea, JD Linderman, AE O'Mara, KY Zhu, AM Cypess |
The Journal of biological chemistry | 2019 |
|
Mechanisms linking adipose tissue inflammation to cardiac hypertrophy and fibrosis
SR Anthony, AR Guarnieri, A Gozdiff, RN Helsley, AP Owens, M Tranter |
Clinical Science | 2019 |
|
Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells
NZ Jespersen, A Feizi, ES Andersen, S Heywood, HB Hattel, S Daugaard, L Peijs, P Bagi, B Feldt-Rasmussen, HS Schultz, NS Hansen, R Krogh-Madsen, BK Pedersen, N Petrovic, S Nielsen, C Scheele |
Molecular Metabolism | 2019 |
|
Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression
A Worthmann, C Schlein, J Berbée, P Rensen, J Heeren, A Bartelt |
Nutrients | 2019 |
|
Activation of Human Brown Adipose Tissue by Capsinoids, Catechins, Ephedrine, and Other Dietary Components: A Systematic Review
FJ Osuna-Prieto, B Martinez-Tellez, G Sanchez-Delgado, CM Aguilera, J Lozano-Sánchez, D Arráez-Román, A Segura-Carretero, JR Ruiz |
Advances in Nutrition | 2019 |
|
Computational modelling of energy balance in individuals with Metabolic Syndrome
YJ Rozendaal, Y Wang, PA Hilbers, NA van Riel |
BMC Systems Biology | 2019 |
|
Characterization of BAT activity in rats using invasive and non-invasive techniques
A Paulus, PA van Ewijk, EB Nascimento, MD Saint-Hubert, G Hendrikx, A Vogg, I Pooters, M Schnijderberg, J Vanderlocht, G Bos, B Brans, VB Schrauwen-Hinderling, FM Mottaghy, M Bauwens, DH Wang |
PloS one | 2019 |
|
The role of DNA methylation in thermogenic adipose biology
H Xiao, S Kang |
Epigenetics : official journal of the DNA Methylation Society | 2019 |
|
BCAA catabolism in brown fat controls energy homeostasis through SLC25A44
T Yoneshiro, Q Wang, K Tajima, M Matsushita, H Maki, K Igarashi, Z Dai, PJ White, RW McGarrah, OR Ilkayeva, Y Deleye, Y Oguri, M Kuroda, K Ikeda, H Li, A Ueno, M Ohishi, T Ishikawa, K Kim, Y Chen, CH Sponton, RN Pradhan, H Majd, VJ Greiner, M Yoneshiro, Z Brown, M Chondronikola, H Takahashi, T Goto, T Kawada, L Sidossis, FC Szoka, MT McManus, M Saito, T Soga, S Kajimura |
Nature | 2019 |
|
Quantification of the Capacity for Cold-Induced Thermogenesis in Young Men With and Without Obesity
RJ Brychta, S Huang, J Wang, BP Leitner, JD Hattenbach, SL Bell, LA Fletcher, RP Wood, CR Idelson, CJ Duckworth, S McGehee, AB Courville, SB Bernstein, ML Reitman, AM Cypess, KY Chen |
The Journal of clinical endocrinology and metabolism | 2019 |
|
Contribution of brown adipose tissue to human energy metabolism
R Fernández-Verdejo, KL Marlatt, E Ravussin, JE Galgani |
Molecular Aspects of Medicine | 2019 |
|
Brown and Brite: The Fat Soldiers in the Anti-obesity Fight
S Srivastava, RL Veech |
Frontiers in physiology | 2019 |
|
The beneficial effects of brown adipose tissue transplantation
JD White, RS Dewal, KI Stanford |
Molecular Aspects of Medicine | 2019 |
|
12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat
LO Leiria, CH Wang, MD Lynes, K Yang, F Shamsi, M Sato, S Sugimoto, EY Chen, V Bussberg, NR Narain, BE Sansbury, J Darcy, TL Huang, SD Kodani, M Sakaguchi, AL Rocha, TJ Schulz, A Bartelt, GS Hotamisligil, MF Hirshman, K van Leyen, LJ Goodyear, M Blüher, AM Cypess, MA Kiebish, M Spite, YH Tseng |
Cell Metabolism | 2019 |
|
The proposed systemic thermogenic metabolites succinate and 12,13-diHOME are inversely associated with adiposity and related metabolic traits: evidence from a large human cross-sectional study
SK Vasan, R Noordam, MS Gowri, MJ Neville, F Karpe, C Christodoulides |
Diabetologia | 2019 |
|
Glucoregulatory responses to hypothalamic preoptic area cooling
K Muta, ME Matsen, NK Acharya, D Stefanovski, RN Bergman, MW Schwartz, GJ Morton |
Brain Research | 2019 |
|
MiR-27b-3p Inhibition Enhances Browning of Epididymal Fat in High-Fat Diet Induced Obese Mice
J Yu, Y Lv, F Wang, X Kong, W Di, J Liu, Y Sheng, S Lv, G Ding |
Frontiers in Endocrinology | 2019 |
|
Applicability of Supraclavicular Oxygenated and Total Hemoglobin Evaluated by Near-Infrared Time-Resolved Spectroscopy as Indicators of Brown Adipose Tissue Density in Humans
S Nirengi, S Fuse, S Amagasa, T Homma, R Kime, M Kuroiwa, T Endo, N Sakane, M Matsushita, M Saito, Y Kurosawa, T Hamaoka |
International journal of molecular sciences | 2019 |
|
Exposure to Cold Unmasks Potential Biomarkers of Fibromyalgia Syndrome Reflecting Insufficient Sympathetic Responses to Stress:
JV Pardo, RC Larson, RJ Spencer, JT Lee, JD Pasley, CJ Torkelson, AA Larson |
The Clinical Journal of Pain | 2019 |
|
Association of circulating exosomal miR-122 levels with BAT activity in healthy humans
Y Okamatsu-Ogura, M Matsushita, JV Bariuan, K Nagaya, A Tsubota, M Saito |
Scientific Reports | 2019 |
|
Comparison of the Effects of Browning-Inducing Capsaicin on Two Murine Adipocyte Models
T Montanari, F Boschi, M Colitti |
Frontiers in physiology | 2019 |
|
ROCK2 inhibition enhances the thermogenic program in white and brown fat tissue in mice
L Wei, M Surma, Y Yang, S Tersey, J Shi |
The FASEB Journal | 2019 |
|
Is Neuronal Histamine Signaling Involved in Cancer Cachexia? Implications and Perspectives
H Zwickl, E Zwickl-Traxler, M Pecherstorfer |
Frontiers in Oncology | 2019 |
|
Non-invasive in vivo imaging of UCP1 expression in live mice via near-infrared fluorescent protein iRFP720
A Fukuda, S Honda, N Fujioka, Y Sekiguchi, S Mizuno, Y Miwa, F Sugiyama, Y Hayashi, K Nishimura, K Hisatake, K Sun |
PloS one | 2019 |
|
A comprehensive diagnostic approach to detect underlying causes of obesity in adults
ES Valk, EL Akker, M Savas, L Kleinendorst, JA Visser, MM Haelst, AM Sharma, EF Rossum |
Obesity reviews : an official journal of the International Association for the Study of Obesity | 2019 |
|
The long noncoding RNA Blnc1 orchestrates homeostatic adipose tissue remodeling to preserve metabolic health
XY Zhao, S Li, JL DelProposto, T Liu, L Mi, C Porsche, X Peng, CN Lumeng, JD Lin |
Molecular Metabolism | 2018 |
|
Cdkn2a deficiency promotes adipose tissue browning
N Rabhi, SA Hannou, X Gromada, E Salas, , F Oger, C Carney, IC Lopez-Mejia, E Durand, I Rabearivelo, A Bonnefond, E Caron, L Fajas, C Dani, P Froguel, JS Annicotte |
Molecular Metabolism | 2018 |
|
LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat
E Schmidt, I Dhaouadi, I Gaziano, M Oliverio, P Klemm, M Awazawa, G Mitterer, E Fernandez-Rebollo, M Pradas-Juni, W Wagner, P Hammerschmidt, R Loureiro, C Kiefer, NR Hansmeier, S Khani, M Bergami, M Heine, E Ntini, P Frommolt, P Zentis, UA Ørom, J Heeren, M Blüher, M Bilban, JW Kornfeld |
Nature Communications | 2018 |
|
Brown Adipose Tissue
A Pfeifer, M Klingenspor, S Herzig |
2018 | |
|
Development, activation, and therapeutic potential of thermogenic adipocytes
MP Emont, D Kim, J Wu |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2018 |
|
An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling
H Jun, H Yu, J Gong, J Jiang, X Qiao, E Perkey, D Kim, MP Emont, AG Zestos, JS Cho, J Liu, RT Kennedy, I Maillard, XZ Xu, J Wu |
Nature Medicine | 2018 |
|
PPARs and Metabolic Disorders Associated with Challenged Adipose Tissue Plasticity
P Corrales, A Vidal-Puig, G Medina-Gómez |
International journal of molecular sciences | 2018 |
|
Novel Insights into How Overnutrition Disrupts the Hypothalamic Actions of Leptin
S Fruhwürth, H Vogel, A Schürmann, KJ Williams |
Frontiers in Endocrinology | 2018 |
|
Norepinephrine and T4 Are Predictors of Fat Mass Gain in Humans With Cold-Induced Brown Adipose Tissue Activation
B Begaye, P Piaggi, MS Thearle, K Haskie, M Walter, M Schlögl, S Bonfiglio, J Krakoff, KL Vinales |
The Journal of clinical endocrinology and metabolism | 2018 |
|
Interleukin-6 induces fat loss in cancer cachexia by promoting white adipose tissue lipolysis and browning
J Han, Q Meng, L Shen, G Wu |
Lipids in Health and Disease | 2018 |
|
PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-induced obese mice
NJ Song, SH Chang, S Kim, V Panic, BH Jang, UJ Yun, JH Choi, Z Li, KM Park, JH Yoon, S Kim, JH Yoo, J Ling, K Thomas, CJ Villanueva, DY Li, JY Ahn, JM Ku, KW Park |
Cell Death and Disease | 2018 |
|
The Common and Distinct Features of Brown and Beige Adipocytes
K Ikeda, P Maretich, S Kajimura |
Trends in endocrinology and metabolism: TEM | 2018 |
|
Brown Adipose Tissue Energy Metabolism in Humans
AC Carpentier, DP Blondin, KA Virtanen, D Richard, F Haman, ÉE Turcotte |
Frontiers in Endocrinology | 2018 |
|
Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes
DF Pisani, V Barquissau, JC Chambard, D Beuzelin, RA Ghandour, M Giroud, A Mairal, S Pagnotta, S Cinti, D Langin, EZ Amri |
Molecular Metabolism | 2018 |
|
The dipeptidyl peptidase-4 (DPP-4) inhibitor teneligliptin enhances brown adipose tissue function, thereby preventing obesity in mice
K Takeda, H Sawazaki, H Takahashi, YS Yeh, HF Jheng, W Nomura, T Ara, N Takahashi, S Seno, N Osato, H Matsuda, T Kawada, T Goto |
FEBS Open Bio | 2018 |
|
Thermal stress induces glycolytic beige fat formation via a myogenic state
Y Chen, K Ikeda, T Yoneshiro, A Scaramozza, K Tajima, Q Wang, K Kim, K Shinoda, CH Sponton, Z Brown, A Brack, S Kajimura |
Nature | 2018 |
|
Regulation of Energy Expenditure and Brown/Beige Thermogenic Activity by Interleukins: New Roles for Old Actors
M García, P Pazos, L Lima, C Diéguez |
International journal of molecular sciences | 2018 |
|
Brown and beige adipose tissues: phenotype and metabolic potential in mice and men
K Chechi, W van Marken Lichtenbelt, D Richard |
Journal of applied physiology | 2018 |
|
Is activation of human brown adipose tissue a viable target for weight management?
KL Marlatt, KY Chen, E Ravussin |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2018 |
|
Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation
NM Held, EN Kuipers, M van Weeghel, JB van Klinken, SW Denis, M Lombès, RJ Wanders, FM Vaz, PC Rensen, AJ Verhoeven, MR Boon, RH Houtkooper |
Scientific Reports | 2018 |
|
Mechanism Underlying Tissue Cryotherapy to Combat Obesity/Overweight: Triggering Thermogenesis
S Loap, R Lathe |
Journal of Obesity | 2018 |
|
Effects of tunable, 3D-bioprinted hydrogels on human brown adipocyte behavior and metabolic function
M Kuss, J Kim, D Qi, S Wu, Y Lei, S Chung, B Duan |
Acta Biomaterialia | 2018 |
|
Brown adipocyte glucose metabolism: a heated subject
MK Hankir, M Klingenspor |
EMBO reports | 2018 |
|
Effect of l-arginine on energy metabolism, skeletal muscle and brown adipose tissue in South Asian and Europid prediabetic men: a randomised double-blinded crossover study
MR Boon, MJ Hanssen, B Brans, CJ Hülsman, J Hoeks, KJ Nahon, C Bakker, JB van Klinken, B Havekes, G Schaart, IM Jazet, PC Rensen, WD van Marken Lichtenbelt |
Diabetologia | 2018 |
|
The circadian clock in white and brown adipose tissue: mechanistic, endocrine and clinical aspects
O Froy, M Garaulet |
Endocrine reviews | 2018 |
|
Multifaceted Roles of Beige Fat in Energy Homeostasis Beyond UCP1
CH Sponton, S Kajimura |
Endocrinology | 2018 |
|
Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis
E Paulo, D Wu, Y Wang, Y Zhang, Y Wu, DL Swaney, M Soucheray, D Jimenez-Morales, A Chawla, NJ Krogan, B Wang |
Scientific Reports | 2018 |
|
A direct tissue-grafting approach to increasing endogenous brown fat
NR Blumenfeld, HJ Kang, A Fenzl, Z Song, JJ Chung, R Singh, R Johnson, A Karakecili, JB Feranil, NS Rossen, V Zhang, S Jaggi, B McCarty, S Bessler, GJ Schwartz, R Grant, J Korner, FW Kiefer, BM Gillette, SK Sia |
Scientific Reports | 2018 |
|
GSK3 is a negative regulator of the thermogenic program in brown adipocytes
LK Markussen, S Winther, B Wicksteed, JB Hansen |
Scientific Reports | 2018 |
|
Fighting obesity by targeting factors regulating beige adipocytes:
AE McQueen, SK Koliwad, JC Wang |
Current Opinion in Clinical Nutrition and Metabolic Care | 2018 |
|
The Global Epidemic of the Metabolic Syndrome
MG Saklayen |
Current Hypertension Reports | 2018 |
|
Supra-pharmacological concentration of capsaicin stimulates brown adipogenesis through induction of endoplasmic reticulum stress
R Kida, T Noguchi, M Murakami, O Hashimoto, T Kawada, T Matsui, M Funaba |
Scientific Reports | 2018 |
|
Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation
EL Brown, BC Hazen, E Eury, JS Wattez, ML Gantner, V Albert, S Chau, M Sanchez-Alavez, B Conti, A Kralli |
iScience | 2018 |
|
Seasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environment
S Nirengi, N Sakane, S Amagasa, S Wakui, T Homma, Y Kurosawa, T Hamaoka |
Journal of PHYSIOLOGICAL ANTHROPOLOGY | 2018 |
|
Trans-Ferulic Acid-4-β-Glucoside Alleviates Cold-Induced Oxidative Stress and Promotes Cold Tolerance
C Xue, H Lu, Y Liu, J Zhang, J Wang, W Luo, W Zhang, J Chen |
International journal of molecular sciences | 2018 |
|
RPS3A positively regulates the mitochondrial function of human periaortic adipose tissue and is associated with coronary artery diseases
Y Tang, Y He, C Li, W Mu, Y Zou, C Liu, S Qian, F Zhang, J Pan, Y Wang, H Huang, D Pan, P Yang, J Mei, R Zeng, Q Tang |
Cell Discovery | 2018 |
|
Outdoor Temperature Influences Cold Induced Thermogenesis in Humans
JR Senn, CI Maushart, G Gashi, R Michel, ML dEpinay, R Vogt, AS Becker, J Müller, M Baláz, C Wolfrum, IA Burger, MJ Betz |
Frontiers in physiology | 2018 |
|
N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes
K Huber, DC Hofer, S Trefely, HJ Pelzmann, C Madreiter-Sokolowski, M Duta-Mare, S Schlager, G Trausinger, S Stryeck, WF Graier, D Kolb, C Magnes, NW Snyder, A Prokesch, D Kratky, T Madl, KE Wellen, JG Bogner-Strauss |
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2018 |
|
Fasting-dependent Vascular Permeability Enhancement in Brown Adipose Tissues Evidenced by Using Carbon Nanotubes as Fluorescent Probes
M Yudasaka, Y Yomogida, M Zhang, M Nakahara, N Kobayashi, T Tanaka, Y Okamatsu-Ogura, K Saeki, H Kataura |
Scientific Reports | 2018 |
|
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes
C Clemmensen, S Jall, M Kleinert, C Quarta, T Gruber, J Reber, S Sachs, K Fischer, A Feuchtinger, A Karlas, SE Simonds, G Grandl, D Loher, E Sanchez-Quant, S Keipert, M Jastroch, SM Hofmann, EB Nascimento, P Schrauwen, V Ntziachristos, MA Cowley, B Finan, TD Müller, MH Tschöp |
Nature Communications | 2018 |
|
Exercise Induces White Adipose Tissue Browning Across the Weight Spectrum in Humans
B Otero-Díaz, M Rodríguez-Flores, V Sánchez-Muñoz, F Monraz-Preciado, S Ordoñez-Ortega, V Becerril-Elias, G Baay-Guzmán, R Obando-Monge, E García-García, B Palacios-González, MT Villarreal-Molina, M Sierra-Salazar, B Antuna-Puente |
Frontiers in physiology | 2018 |
|
Parathyroid hormone induces a browning program in human white adipocytes
OC Hedesan, A Fenzl, A Digruber, K Spirk, S Baumgartner-Parzer, M Bilban, L Kenner, M Vierhapper, A Elbe-Bürger, FW Kiefer |
International Journal of Obesity | 2018 |
|
Daily intake of Kaempferia parviflora extract decreases abdominal fat in overweight and preobese subjects: a randomized, double-blind, placebo-controlled clinical study
S Yoshino, R Awa, Y Miyake, I Fukuhara, H Sato, T Ashino, S Tomita, H Kuwahara |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy | 2018 |
|
The GPR 120 agonist TUG ‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat
M Schilperoort, AD Dam, G Hoeke, IG Shabalina, A Okolo, AC Hanyaloglu, LH Dib, IM Mol, N Caengprasath, YW Chan, S Damak, AR Miller, T Coskun, B Shimpukade, T Ulven, S Kooijman, PC Rensen, M Christian |
EMBO Molecular Medicine | 2018 |
|
Tetrahydrobiopterin activates brown adipose tissue and regulates systemic energy metabolism
Yasuo Oguri, Yoshihito Fujita, Abulizi Abudukadier, Akiko Ohashi, Tsuyoshi Goto, Futoshi Furuya, Akio Obara, Toru Fukushima, Naomi Matsuo, Minji Kim, Masaya Hosokawa, Teruo Kawada, Hiroyuki Hasegawa, Nobuya Inagaki |
JCI Insight | 2017 |
|
Involvement of thermosensitive TRP channels in energy metabolism
K Uchida, K Dezaki, T Yoneshiro, T Watanabe, J Yamazaki, M Saito, T Yada, M Tominaga, Y Iwasaki |
The Journal of Physiological Sciences | 2017 |
|
FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes
MZ Chen, JC Chang, J Zavala-Solorio, L Kates, M Thai, A Ogasawara, X Bai, S Flanagan, V Nunez, K Phamluong, J Ziai, R Newman, S Warming, G Kolumam, J Sonoda |
Molecular Metabolism | 2017 |
|
Myricetin-induced brown adipose tissue activation prevents obesity and insulin resistance in db/db mice
T Hu, X Yuan, G Wei, H Luo, HJ Lee, W Jin |
European Journal of Nutrition | 2017 |
|
Traveling from the hypothalamus to the adipose tissue: the thermogenic pathway
C Contreras, R Nogueiras, C Diéguez, K Rahmouni, M López |
Redox Biology | 2017 |
|
Bone marrow adipocytes
MC Horowitz, R Berry, B Holtrup, Z Sebo, T Nelson, JA Fretz, D Lindskog, JL Kaplan, G Ables, MS Rodeheffer, CJ Rosen |
Adipocyte | 2017 |
|
The Role of the Autonomic Nervous System in the Pathophysiology of Obesity
D Guarino, M Nannipieri, G Iervasi, S Taddei, RM Bruno |
Frontiers in physiology | 2017 |
|
DJ-1 maintains energy and glucose homeostasis by regulating the function of brown adipose tissue
R Wu, X Liu, J Sun, H Chen, J Ma, M Dong, S Peng, J Wang, J Ding, D Li, JR Speakman, G Ning, W Jin, Z Yuan |
Cell Discovery | 2017 |
|
Metabolic regulation and the anti-obesity perspectives of human brown fat
C Scheele, S Nielsen |
Redox Biology | 2017 |
|
The role of declining adaptive homeostasis in ageing: Ageing decline in adaptive homeostasis
LC Pomatto, KJ Davies |
The Journal of Physiology | 2017 |
|
Nutritional approaches for managing obesity-associated metabolic diseases
R Botchlett, SL Woo, M Liu, Y Pei, X Guo, H Li, C Wu |
Journal of Endocrinology | 2017 |
|
Shortcuts to a functional adipose tissue: The role of small non-coding RNAs
BB Brandão, BA Guerra, MA Mori |
Redox Biology | 2017 |
|
The hepatokine FGF21 is crucial for peroxisome proliferator-activated receptor-α agonist-induced amelioration of metabolic disorders in obese mice
T Goto, M Hirata, Y Aoki, M Iwase, H Takahashi, M Kim, Y Li, HF Jheng, W Nomura, N Takahashi, CS Kim, R Yu, S Seno, H Matsuda, M Aizawa-Abe, K Ebihara, N Itoh, T Kawada |
The Journal of biological chemistry | 2017 |
|
Role of brown adipose tissue in metabolic syndrome, aging, and cancer cachexia
M Dong, J Lin, W Lim, W Jin, HJ Lee |
Frontiers of Medicine | 2017 |
|
Pioglitazone reduces cold-induced brown fat glucose uptake despite induction of browning in cultured human adipocytes: a randomised, controlled trial in humans
RK Loh, MF Formosa, N Eikelis, DA Bertovic, MJ Anderson, SA Barwood, S Nanayakkara, ND Cohen, AL Gerche, AT Reutens, KS Yap, TW Barber, GW Lambert, MH Cherk, SJ Duffy, BA Kingwell, AL Carey |
Diabetologia | 2017 |
|
Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis
J Sanchez-Gurmaches, Y Tang, NZ Jespersen, M Wallace, CM Calejman, S Gujja, H Li, YJ Edwards, C Wolfrum, CM Metallo, S Nielsen, C Scheele, DA Guertin |
Cell Metabolism | 2017 |
|
Targeting thermogenesis in brown fat and muscle to treat obesity and metabolic disease
MJ Betz, S Enerbäck |
Nature Reviews Endocrinology | 2017 |
|
Mitochondrial homeostasis in adipose tissue remodeling
S Altshuler-Keylin, S Kajimura |
Science signaling | 2017 |
|
EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex
SN Shapira, HW Lim, S Rajakumari, AP Sakers, J Ishibashi, MJ Harms, KJ Won, P Seale |
Genes & development | 2017 |
|
Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein α
Z Song, AM Xiaoli, Q Zhang, Y Zhang, ES Yang, S Wang, R Chang, ZD Zhang, G Yang, R Strich, JE Pessin, F Yang |
The Journal of biological chemistry | 2017 |
|
Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression
A Fukunaka, T Fukada, J Bhin, L Suzuki, T Tsuzuki, Y Takamine, BH Bin, T Yoshihara, N Ichinoseki-Sekine, H Naito, T Miyatsuka, S Takamiya, T Sasaki, T Inagaki, T Kitamura, S Kajimura, H Watada, Y Fujitani, GS Barsh |
PLoS genetics | 2017 |
|
Crosstalk between KCNK3-Mediated Ion Current and Adrenergic Signaling Regulates Adipose Thermogenesis and Obesity
Y Chen, X Zeng, X Huang, S Serag, CJ Woolf, BM Spiegelman |
Cell | 2017 |
|
Epigenetic Regulation of the Thermogenic Adipose Program
A Sambeat, O Gulyaeva, J Dempersmier, HS Sul |
Trends in Endocrinology & Metabolism | 2017 |
|
Brown Adipose Tissue: an Update on Recent Findings
KL Marlatt, E Ravussin |
Current Obesity Reports | 2017 |
|
Loss of MyoD Promotes Fate Transdifferentiation of Myoblasts Into Brown Adipocytes
C Wang, W Liu, Y Nie, M Qaher, HE Horton, F Yue, A Asakura, S Kuang |
EBioMedicine | 2017 |
|
Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans
DC Berry, Y Jiang, RW Arpke, EL Close, A Uchida, D Reading, ED Berglund, M Kyba, JM Graff |
Cell Metabolism | 2017 |
|
Systems biology reveals uncoupling beyond UCP1 in human white fat-derived beige adipocytes
E Nyman, S Bartesaghi, RM Rydfalk, S Eng, C Pollard, P Gennemark, XR Peng, G Cedersund |
npj Systems Biology and Applications | 2017 |
|
The significance of beige and brown fat in humans
FW Kiefer |
Endocrine Connections | 2017 |
|
Loading and firing the brown adipocyte
MK Hankir |
Adipocyte | 2017 |
|
Conserved function of the long noncoding RNA Blnc1 in brown adipocyte differentiation
L Mi, XY Zhao, S Li, G Yang, JD Lin |
Molecular Metabolism | 2017 |
|
Four-week cold acclimation in adult humans shifts uncoupling thermogenesis from skeletal muscles to brown adipose tissue: Cold-acclimation increases muscle efficiency
DP Blondin, A Daoud, T Taylor, HC Tingelstad, V Bézaire, D Richard, AC Carpentier, AW Taylor, ME Harper, C Aguer, F Haman |
The Journal of Physiology | 2017 |
|
Dietary fatty acid metabolism of brown adipose tissue in cold-acclimated men
DP Blondin, HC Tingelstad, C Noll, F Frisch, S Phoenix, B Guérin, ÉE Turcotte, D Richard, F Haman, AC Carpentier |
Nature Communications | 2017 |
|
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
A Bartelt, C John, N Schaltenberg, JF Berbée, A Worthmann, ML Cherradi, C Schlein, J Piepenburg, MR Boon, F Rinninger, M Heine, K Toedter, A Niemeier, SK Nilsson, M Fischer, SL Wijers, WM Lichtenbelt, L Scheja, PC Rensen, J Heeren |
Nature Communications | 2017 |
|
Brown adipose tissue is associated with systemic concentrations of peptides secreted from the gastrointestinal system and involved in appetite regulation
M Chondronikola, C Porter, I Malagaris, AA Nella, LS Sidossis |
European Journal of Endocrinology | 2017 |
|
Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation
Y Jiang, DC Berry, JM Graff |
eLife | 2017 |
|
11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice
CL Doig, RS Fletcher, SA Morgan, EL McCabe, DP Larner, JW Tomlinson, PM Stewart, A Philp, GG Lavery |
Endocrinology | 2017 |
|
LysoPC-acyl C16:0 is associated with brown adipose tissue activity in men
MR Boon, LE Bakker, C Prehn, J Adamski, MJ Vosselman, IM Jazet, LM Arias-Bouda, WD van Lichtenbelt, KW van Dijk, PC Rensen, DO Mook-Kanamori |
Metabolomics | 2017 |
|
Variable Cold-Induced Brown Adipose Tissue Response to Thyroid Hormone Status
A Gavrila, PO Hasselgren, A Glasgow, AN Doyle, AJ Lee, P Fox, S Gautam, JV Hennessey, GM Kolodny, AM Cypess |
Thyroid | 2017 |
|
Effect of repeated forearm muscle cooling on the adaptation of skeletal muscle metabolism in humans
H Wakabayashi, T Nishimura, T Wijayanto, S Watanuki, Y Tochihara |
International Journal of Biometeorology | 2017 |
|
Chronic high-fat feeding impairs adaptive induction of mitochondrial fatty acid combustion-associated proteins in brown adipose tissue of mice
T Ohtomo, K Ino, R Miyashita, M Chigira, M Nakamura, K Someya, N Inaba, M Fujita, M Takagi, J Yamada |
Biochemistry and Biophysics Reports | 2017 |
|
Metabolic Responses to the Yukon Arctic Ultra: Longest and Coldest in the World
RH Coker, AN Weaver, MS Coker, CJ Murphy, HC Gunga, M Steinach |
Medicine and Science in Sports and Exercise | 2017 |
|
Electroacupuncture Promotes Central Nervous System-Dependent Release of Mesenchymal Stem Cells: EA Promotes CNS-Dependent Release of MSC
TE Salazar, MR Richardson, E Beli, MS Ripsch, J George, Y Kim, Y Duan, L Moldovan, Y Yan, A Bhatwadekar, V Jadhav, JA Smith, S McGorray, AL Bertone, DO Traktuev, KL March, LM Colon-Perez, KG Avin, E Sims, JA Mund, J Case, X Deng, MS Kim, B McDavitt, ME Boulton, J Thinschmidt, SL Calzi, SD Fitz, RK Fuchs, SJ Warden, T McKinley, A Shekhar, M Febo, PL Johnson, LJ Chang, Z Gao, MG Kolonin, S Lai, J Ma, X Dong, FA White, H Xie, MC Yoder, MB Grant |
Stem Cells | 2017 |
|
Who is the Iceman?
WM Lichtenbelt |
Temperature | 2017 |
|
Experimental evidence reveals the UCP1 genotype changes the oxygen consumption attributed to non-shivering thermogenesis in humans
T Nishimura, T Katsumura, M Motoi, H Oota, S Watanuki |
Scientific Reports | 2017 |
|
Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis
S Li, L Mi, L Yu, Q Yu, T Liu, GX Wang, XY Zhao, J Wu, JD Lin |
Proceedings of the National Academy of Sciences | 2017 |
|
Enhancing brown fat with NFIA
SN Shapira, P Seale |
Nature Cell Biology | 2017 |
|
Diabetes incidence and glucose intolerance prevalence increase with higher outdoor temperature
LL Blauw, NA Aziz, MR Tannemaat, CA Blauw, AJ de Craen, H Pijl, PC Rensen |
BMJ Open Diabetes Research & Care | 2017 |
|
Hop Phytochemicals and Their Potential Role in Metabolic Syndrome Prevention and Therapy
P Dostálek, M Karabín, L Jelínek |
Molecules (Basel, Switzerland) | 2017 |
|
The neuropeptide TLQP-21 opposes obesity via C3aR1-mediated enhancement of adrenergic-induced lipolysis
C Cero, M Razzoli, R Han, BS Sahu, J Patricelli, ZK Guo, NA Zaidman, JM Miles, SM O'Grady, A Bartolomucci |
Molecular Metabolism | 2017 |
|
Dietary Factors Promoting Brown and Beige Fat Development and Thermogenesis
M Okla, J Kim, K Koehler, S Chung |
Advances in nutrition (Bethesda, Md.) | 2017 |
|
Impairment of body mass reduction-associated activation of brown/beige adipose tissue in patients with type 2 diabetes mellitus
S Rodovalho, B Rachid, JC De-Lima-Junior, S van de Sande-Lee, J Morari, HM Carvalho, BJ Amorim, AJ Tincani, E Chaim, JC Pareja, MJ Saad, F Folli, CD Ramos, B Geloneze, LA Velloso |
International Journal of Obesity | 2017 |
|
Genetic variation in the obesity gene FTO is not associated with decreased fat oxidation: the NEO study
LL Blauw, R Noordam, S Trompet, JF Berbée, FR Rosendaal, D van Heemst, KW van Dijk, DO Mook-Kanamori, R de Mutsert, PC Rensen |
International Journal of Obesity | 2017 |
|
A novel thermoregulatory role for PDE10A in mouse and human adipocytes
MK Hankir, M Kranz, T Gnad, J Weiner, S Wagner, W DeutherConrad, F Bronisch, K Steinhoff, J Luthardt, N Klöting, S Hesse, JP Seibyl, O Sabri, JT Heiker, M Blüher, A Pfeifer, P Brust, WK Fenske |
EMBO Molecular Medicine | 2016 |
|
The Dichotomous Effect of Chronic Stress on Obesity
M Razzoli, A Bartolomucci |
Trends in Endocrinology & Metabolism | 2016 |
|
Combatting type 2 diabetes by turning up the heat
P Schrauwen, WD van Lichtenbelt |
Diabetologia | 2016 |
|
Dicer1–miR-328–Bace1 signalling controls brown adipose tissue differentiation and function
M Oliverio, E Schmidt, J Mauer, C Baitzel, N Hansmeier, S Khani, S Konieczka, M Pradas-Juni, S Brodesser, TM Van, D Bartsch, HS Brönneke, M Heine, H Hilpert, E Tarcitano, GA Garinis, P Frommolt, J Heeren, MA Mori, JC Brüning, JW Kornfeld |
Nature Cell Biology | 2016 |
|
Human pluripotent stem cells: Towards therapeutic development for the treatment of lifestyle diseases
M Nishio |
World journal of stem cells | 2016 |
|
The role of innate immunity in the regulation of brown and beige adipogenesis
VI Alexaki, T Chavakis |
Reviews in Endocrine and Metabolic Disorders | 2016 |
|
AHNAK deficiency promotes browning and lipolysis in mice via increased responsiveness to β-adrenergic signalling
JH Shin, SH Lee, YN Kim, IY Kim, YJ Kim, DS Kyeong, HJ Lim, SY Cho, J Choi, YJ Wi, JH Choi, YS Yoon, YS Bae, JK Seong |
Scientific Reports | 2016 |
|
Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation
LM Krott, F Piscitelli, M Heine, S Borrino, L Scheja, C Silvestri, J Heeren, VD Marzo |
Journal of lipid research | 2016 |
|
Brown adipose tissue: The heat is on the heart
R Thoonen, AG Hindle, M Scherrer-Crosbie |
American journal of physiology. Heart and circulatory physiology | 2016 |
|
Adipose tissue in control of metabolism
L Luo, M Liu |
Journal of Endocrinology | 2016 |
|
Targeting adipose tissue in the treatment of obesity-associated diabetes
CM Kusminski, PE Bickel, PE Scherer |
Nature Reviews Drug Discovery | 2016 |
|
Biology of Beige Adipocyte and Possible Therapy for Type 2 Diabetes and Obesity
F Lizcano, D Vargas |
International Journal of Endocrinology | 2016 |
|
Mechanisms of metabolic dysfunction in cancer-associated cachexia
M Petruzzelli, EF Wagner |
Genes & development | 2016 |
|
Transcriptional and epigenetic control of brown and beige adipose cell fate and function
T Inagaki, J Sakai, S Kajimura |
Nature Reviews Molecular Cell Biology | 2016 |
|
Emerging Roles of Adipose Progenitor Cells in Tissue Development, Homeostasis, Expansion and Thermogenesis
DC Berry, Y Jiang, JM Graff |
Trends in Endocrinology & Metabolism | 2016 |
|
Novel Browning Agents, Mechanisms, and Therapeutic Potentials of Brown Adipose Tissue
UD Wankhade, M Shen, H Yadav, KM Thakali |
BioMed Research International | 2016 |
|
Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance
S Altshuler-Keylin, K Shinoda, Y Hasegawa, K Ikeda, H Hong, Q Kang, Y Yang, RM Perera, J Debnath, S Kajimura |
Cell Metabolism | 2016 |
|
Control of brown and beige fat development
W Wang, P Seale |
Nature Reviews Molecular Cell Biology | 2016 |
|
A Synergistic Antiobesity Effect by a Combination of Capsinoids and Cold Temperature Through Promoting Beige Adipocyte Biogenesis
K Ohyama, Y Nogusa, K Shinoda, K Suzuki, M Bannai, S Kajimura |
Diabetes | 2016 |
|
The critical period for brown adipocyte development: Genetic and environmental influences: Brown Adipocyte Development
A Chabowska-Kita, LP Kozak |
Obesity | 2016 |
|
Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice
S Hanatani, H Motoshima, Y Takaki, S Kawasaki, M Igata, T Matsumura, T Kondo, T Senokuchi, N Ishii, J Kawashima, D Kukidome, S Shimoda, T Nishikawa, E Araki |
Journal of Clinical Biochemistry and Nutrition | 2016 |
|
Brown Fat and Browning for the Treatment of Obesity and Related Metabolic Disorders
SH Kim, J Plutzky |
Diabetes & Metabolism Journal | 2016 |
|
Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3
T Shan, Y Xiong, P Zhang, Z Li, Q Jiang, P Bi, F Yue, G Yang, Y Wang, X Liu, S Kuang |
Nature Communications | 2016 |
|
Metabolic programming of a beige adipocyte phenotype by genistein
SA Aziz, LA Wakeling, S Miwa, G Alberdi, JE Hesketh, D Ford |
Molecular Nutrition & Food Research | 2016 |
|
Clozapine modifies the differentiation program of human adipocytes inducing browning
E Kristóf, QM Doan-Xuan, AK Sárvári, Á Klusóczki, P Fischer-Posovszky, M Wabitsch, Z Bacso, P Bai, Z Balajthy, L Fésüs |
Translational Psychiatry | 2016 |
|
Direct lentivirus injection for fast and efficient gene transfer into brown and beige adipose tissue
A Balkow, LS Hoffmann, K Klepac, A Glöde, T Gnad, K Zimmermann, A Pfeifer |
Journal of Biological Methods | 2016 |
|
Thyroid hormones induce browning of white fat
N Martínez-Sánchez, JM Moreno-Navarrete, C Contreras, E Rial-Pensado, J Fernø, R Nogueiras, C Diéguez, JM Fernández-Real, M López |
Journal of Endocrinology | 2016 |
|
Emerging Complexities in Adipocyte Origins and Identity
J Sanchez-Gurmaches, CM Hung, DA Guertin |
Trends in Cell Biology | 2016 |
|
Brown Adipose Reporting Criteria in Imaging STudies (BARCIST 1.0): Recommendations for Standardized FDG-PET/CT Experiments in Humans
KY Chen, AM Cypess, MR Laughlin, CR Haft, HH Hu, MA Bredella, S Enerbäck, PE Kinahan, WM Lichtenbelt, FI Lin, JJ Sunderland, KA Virtanen, RL Wahl |
Cell Metabolism | 2016 |
|
Brown Adipose Tissue Is Linked to a Distinct Thermoregulatory Response to Mild Cold in People
M Chondronikola, E Volpi, E Børsheim, T Chao, C Porter, P Annamalai, C Yfanti, SM Labbe, NM Hurren, I Malagaris, F Cesani, LS Sidossis |
Frontiers in physiology | 2016 |
|
Characterizing active and inactive brown adipose tissue in adult humans using PET-CT and MR imaging
A Gifford, TF Towse, RC Walker, MJ Avison, EB Welch |
American journal of physiology. Endocrinology and metabolism | 2016 |
|
Cold-induced thermogenesis in humans
RJ Brychta, KY Chen |
European Journal of Clinical Nutrition | 2016 |
|
Metabolically Active Three-Dimensional Brown Adipose Tissue Engineered from White Adipose-Derived Stem Cells
JP Yang, AE Anderson, A McCartney, X Ory, G Ma, E Pappalardo, J Bader, JH Elisseeff |
Tissue Engineering Part A | 2016 |
|
Complementary Roles of Estrogen-Related Receptors in Brown Adipocyte Thermogenic Function
ML Gantner, BC Hazen, E Eury, EL Brown, A Kralli |
Endocrinology | 2016 |
|
A new method of infrared thermography for quantification of brown adipose tissue activation in healthy adults (TACTICAL): a randomized trial
QY Ang, HJ Goh, Y Cao, Y Li, SP Chan, JL Swain, CJ Henry, MK Leow |
The Journal of Physiological Sciences | 2016 |
|
miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function
M Giroud, DF Pisani, M Karbiener, V Barquissau, RA Ghandour, D Tews, P Fischer-Posovszky, JC Chambard, U Knippschild, T Niemi, M Taittonen, P Nuutila, M Wabitsch, S Herzig, KA Virtanen, D Langin, M Scheideler, EZ Amri |
Molecular Metabolism | 2016 |
|
TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway
S Ghoshal, Q Zhu, A Asteian, H Lin, H Xu, G Ernst, JC Barrow, B Xu, MD Cameron, TM Kamenecka, A Chakraborty |
Molecular Metabolism | 2016 |
|
Daily ingestion of catechin-rich beverage increases brown adipose tissue density and decreases extramyocellular lipids in healthy young women
S Nirengi, S Amagasa, T Homma, T Yoneshiro, S Matsumiya, Y Kurosawa, N Sakane, K Ebi, M Saito, T Hamaoka |
SpringerPlus | 2016 |
|
The effects of indoor and outdoor temperature on metabolic rate and adipose tissue – the Mississippi perspective on the obesity epidemic
JB Turner, A Kumar, CA Koch |
Reviews in Endocrine and Metabolic Disorders | 2016 |
|
Postprandial Increase in Energy Expenditure Correlates with Body Weight Reduction in Patients with Type 2 Diabetes Receiving Diet Therapy
D Sanoyama, M Nagao, A Asai, Y Nakamura, K Sato, Y Nakajima, S Oikawa, H Sugihara |
Journal of Atherosclerosis and Thrombosis | 2016 |
|
Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1
ET Chouchani, L Kazak, MP Jedrychowski, GZ Lu, BK Erickson, J Szpyt, KA Pierce, D Laznik-Bogoslavski, R Vetrivelan, CB Clish, AJ Robinson, SP Gygi, BM Spiegelman |
Nature | 2016 |
|
Human Beige Adipocytes: Epiphenomenon or Drivers of Metabolic Improvements?
QA Wang, PE Scherer |
Trends in Endocrinology & Metabolism | 2016 |
|
Obesity: Slim without the gym — the magic of chilling out
P Iyengar, PE Scherer |
Nature Reviews Endocrinology | 2016 |
|
ELBW survivors in early adulthood have higher hepatic, pancreatic and subcutaneous fat
JD Crane, SA Yellin, FJ Ong, NP Singh, N Konyer, MD Noseworthy, LA Schmidt, S Saigal, KM Morrison |
Scientific Reports | 2016 |
|
Association of circulating neuregulin 4 with metabolic syndrome in obese adults: a cross-sectional study
C Cai, M Lin, Y Xu, X Li, S Yang, H Zhang |
BMC Medicine | 2016 |
|
Brown and Beige Fat in Humans: Thermogenic adipocytes that control energy and glucose homeostasis
Labros Siddossis, Shingo Kajimura |
Journal of Clinical Investigation | 2015 |
|
Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction
C Jiang, C Xie, Y Lv, J Li, KW Krausz, J Shi, CN Brocker, D Desai, SG Amin, WH Bisson, Y Liu, O Gavrilova, AD Patterson, FJ Gonzalez |
Nature Communications | 2015 |
|
Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance
AL Poher, J Altirriba, C Veyrat-Durebex, FÃ Rohner-Jeanrenaud |
Frontiers in physiology | 2015 |
|
Transcriptional control and hormonal response of thermogenic fat
MP Emont, H Yu, J Wu |
Journal of Endocrinology | 2015 |
|
Formation and activation of thermogenic fat
J Wu, H Jun, JR McDermott |
Trends in Genetics | 2015 |
|
The brown fat secretome: metabolic functions beyond thermogenesis
GX Wang, XY Zhao, JD Lin |
Trends in Endocrinology & Metabolism | 2015 |
|
The brown and brite adipocyte marker Cox7a1 is not required for non-shivering thermogenesis in mice
SF Maurer, T Fromme, LI Grossman, M Hüttemann, M Klingenspor |
Scientific Reports | 2015 |
|
Control of Adipocyte Differentiation in Different Fat Depots; Implications for Pathophysiology or Therapy
X Ma, P Lee, DJ Chisholm, DE James |
Frontiers in Endocrinology | 2015 |
|
Fluorescence imaging of interscapular brown adipose tissue in living mice
DR Rice, AG White, WM Leevy, BD Smith |
Journal of Materials Chemistry B | 2015 |
|
Transcriptional Regulatory Circuits Controlling Brown Fat Development and Activation
P Seale |
Diabetes | 2015 |
|
FGF21, energy expenditure and weight loss – How much brown fat do you need?
L Straub, C Wolfrum |
Molecular Metabolism | 2015 |
|
Cognitive and autonomic determinants of energy homeostasis in obesity
D Richard |
Nature Reviews Endocrinology | 2015 |
|
Brown and beige fat: the metabolic function, induction, and therapeutic potential
S Qian, H Huang, Q Tang |
Frontiers of Medicine | 2015 |
|
Adipogenic role of alternatively activated macrophages in β-adrenergic remodeling of white adipose tissue
YH Lee, SN Kim, HJ Kwon, KR Maddipati, JG Granneman |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2015 |
|
Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure
K Shinoda, K Ohyama, Y Hasegawa, HY Chang, M Ogura, A Sato, H Hong, T Hosono, LZ Sharp, DW Scheel, M Graham, Y Ishihama, S Kajimura |
Cell Metabolism | 2015 |
|
Brown and Beige Fat: Molecular Parts of a Thermogenic Machine: Figure 1
P Cohen, BM Spiegelman |
Diabetes | 2015 |
|
Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes
A Than, HL He, SH Chua, D Xu, L Sun, MK Leow, P Chen |
The Journal of biological chemistry | 2015 |
|
Brown and Beige Fat: Physiological Roles beyond Heat Generation
S Kajimura, BM Spiegelman, P Seale |
Cell Metabolism | 2015 |
|
Leptin Signaling Is Required for Adaptive Changes in Food Intake, but Not Energy Expenditure, in Response to Different Thermal Conditions
KJ Kaiyala, K Ogimoto, JT Nelson, MW Schwartz, GJ Morton, JA Chowen |
PloS one | 2015 |
|
The Whitening of Brown Fat and Its Implications for Weight Management in Obesity
I Shimizu, K Walsh |
Current Obesity Reports | 2015 |
|
Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex
G Kolumam, MZ Chen, R Tong, J Zavala-Solorio, L Kates, N Bruggen, J Ross, SK Wyatt, VD Gandham, RA Carano, DR Dunshee, AL Wu, B Haley, K Anderson, S Warming, XY Rairdan, N Lewin-Koh, Y Zhang, J Gutierrez, A Baruch, TR Gelzleichter, D Stevens, S Rajan, TW Bainbridge, JM Vernes, YG Meng, J Ziai, RH Soriano, MJ Brauer, Y Chen, S Stawicki, HS Kim, L Comps-Agrar, E Luis, C Spiess, Y Wu, JA Ernst, OP McGuinness, AS Peterson, J Sonoda |
EBioMedicine | 2015 |
|
Of mice and men: novel insights regarding constitutive and recruitable brown adipocytes
KL Townsend, YH Tseng |
International Journal of Obesity Supplements | 2015 |
|
Bioengineering Beige Adipose Tissue Therapeutics
KM Tharp, A Stahl |
Frontiers in Endocrinology | 2015 |
|
Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist
AM Cypess, LS Weiner, C Roberts-Toler, EF Elía, SH Kessler, PA Kahn, J English, K Chatman, SA Trauger, A Doria, GM Kolodny |
Cell Metabolism | 2015 |
|
Chronic ephedrine administration decreases brown adipose tissue activity in a randomised controlled human trial: implications for obesity
AL Carey, R Pajtak, MF Formosa, BV Every, DA Bertovic, MJ Anderson, N Eikelis, GW Lambert, V Kalff, SJ Duffy, MH Cherk, BA Kingwell |
Diabetologia | 2015 |
|
Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes
R Xue, MD Lynes, JM Dreyfuss, F Shamsi, TJ Schulz, H Zhang, TL Huang, KL Townsend, Y Li, H Takahashi, LS Weiner, AP White, MS Lynes, LL Rubin, LJ Goodyear, AM Cypess, YH Tseng |
Nature Medicine | 2015 |
|
Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus
MJ Hanssen, J Hoeks, B Brans, AA van der Lans, G Schaart, JJ van Driessche, JA Jörgensen, MV Boekschoten, MK Hesselink, B Havekes, S Kersten, FM Mottaghy, WD van Lichtenbelt, P Schrauwen |
Nature Medicine | 2015 |
|
Hypothalamic Regulation of Brown Adipose Tissue Thermogenesis and Energy Homeostasis
W Zhang, S Bi |
Frontiers in Endocrinology | 2015 |
|
The Therapeutic Potential of Brown Adipocytes in Humans
C Porter, M Chondronikola, LS Sidossis |
Frontiers in Endocrinology | 2015 |
|
The thermogenic responses to overfeeding and cold are differentially regulated: DIT and CIT are Differentially Regulated
CM Peterson, V Lecoultre, EA Frost, J Simmons, LM Redman, E Ravussin |
Obesity | 2015 |
|
Molecular Clock Integration of Brown Adipose Tissue Formation and Function
D Nam, VK Yechoor, K Ma |
Adipocyte | 2015 |
|
Surgical injury induces local and distant adipose tissue browning
A Longchamp, M Tao, A Bartelt, K Ding, L Lynch, C Hine, JM Corpataux, BS Kristal, JR Mitchell, CK Ozaki |
Adipocyte | 2015 |
|
Visfatin expression analysis in association with recruitment and activation of human and rodent brown and brite adipocytes
DF Pisani, O Dumortier, GE Beranger, V Casamento, RA Ghandour, M Giroud, N Gautier, T Balaguer, JC Chambard, KA Virtanen, P Nuutila, T Niemi, M Taittonen, EV Obberghen, C Hinault, EZ Amri |
Adipocyte | 2015 |
|
Browning of Subcutaneous White Adipose Tissue in Humans after Severe Adrenergic Stress
LS Sidossis, C Porter, MK Saraf, E Børsheim, RS Radhakrishnan, T Chao, A Ali, M Chondronikola, R Mlcak, CC Finnerty, HK Hawkins, T Toliver-Kinsky, DN Herndon |
Cell Metabolism | 2015 |
|
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
JF Berbée, MR Boon, PP Khedoe, A Bartelt, C Schlein, A Worthmann, S Kooijman, G Hoeke, IM Mol, C John, C Jung, N Vazirpanah, LP Brouwers, PL Gordts, JD Esko, PS Hiemstra, LM Havekes, L Scheja, J Heeren, PC Rensen |
Nature Communications | 2015 |
|
Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis
MW Lee, JI Odegaard, L Mukundan, Y Qiu, AB Molofsky, JC Nussbaum, K Yun, RM Locksley, A Chawla |
Cell | 2015 |
|
Genetic and functional characterization of clonally derived adult human brown adipocytes
K Shinoda, IH Luijten, Y Hasegawa, H Hong, SB Sonne, M Kim, R Xue, M Chondronikola, AM Cypess, YH Tseng, J Nedergaard, LS Sidossis, S Kajimura |
Nature Medicine | 2015 |
|
A Clinical Approach to Brown Adipose Tissue in the Para-Aortic Area of the Human Thorax
H Wei, S Chiba, C Moriwaki, H Kitamura, K Ina, T Aosa, K Tomonari, K Gotoh, T Masaki, I Katsuragi, H Noguchi, T Kakuma, K Hamaguchi, T Shimada, Y Fujikura, H Shibata, A Bartolomucci |
PloS one | 2015 |
|
Central Serotonergic Neurons Activate and Recruit Thermogenic Brown and Beige Fat and Regulate Glucose and Lipid Homeostasis
JM McGlashon, MC Gorecki, AE Kozlowski, CK Thirnbeck, KR Markan, KL Leslie, ME Kotas, MJ Potthoff, GB Richerson, MP Gillum |
Cell Metabolism | 2015 |
|
Shades of Brown: A Model for Thermogenic Fat
J Dempersmier, HS Sul |
Frontiers in Endocrinology | 2015 |
|
Promoting brown and beige adipocyte biogenesis through the PRDM16 pathway
S Kajimura |
International Journal of Obesity Supplements | 2015 |
|
Horizons in the Pharmacotherapy of Obesity
JR Arch |
Current Obesity Reports | 2015 |
|
Matured hop extract reduces body fat in healthy overweight humans: a randomized, double-blind, placebo-controlled parallel group study
Y Morimoto-Kobayashi, K Ohara, H Ashigai, T Kanaya, K Koizumi, F Manabe, Y Kaneko, Y Taniguchi, M Katayama, Y Kowatari, S Kondo |
Nutrition Journal | 2015 |
|
Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images
A Gifford, TF Towse, RC Walker, MJ Avison, EB Welch |
Journal of visualized experiments : JoVE | 2015 |
|
Burn Induces Browning of the Subcutaneous White Adipose Tissue in Mice and Humans
D Patsouris, P Qi, A Abdullahi, M Stanojcic, P Chen, A Parousis, S Amini-Nik, MG Jeschke |
Cell Reports | 2015 |
|
Human whole body cold adaptation
HA Daanen, WD van Lichtenbelt |
Temperature | 2015 |
|
Group housing and nest building only slightly ameliorate the cold stress of typical housing in female C57BL/6J mice
RL Maher, SM Barbash, DV Lynch, SJ Swoap |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2015 |
|
The 16th international symposium in obesity—white, beige, brown: what determines the colour of adipose tissue
Richard D |
International Journal of Obesity Supplements | 2015 |
|
Increased brown adipose tissue oxidative capacity in cold-acclimated humans
DP Blondin, SM Labbé, HC Tingelstad, C Noll, M Kunach, S Phoenix, B Guérin, ÉE Turcotte, AC Carpentier, D Richard, F Haman |
The Journal of clinical endocrinology and metabolism | 2014 |
|
The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms
B Lu, Y Diz-Chaves, D Markovic, A Contarino, L Penicaud, F Fanelli, S Clark, H Lehnert, D Cota, DK Grammatopoulos, A Tabarin |
International Journal of Obesity | 2014 |
|
Temperature-acclimated brown adipose tissue modulates insulin sensitivity in humans
P Lee, S Smith, J Linderman, AB Courville, RJ Brychta, W Dieckmann, CD Werner, KY Chen, FS Celi |
Diabetes | 2014 |
|
Spice Up Your Life: Adipose Tissue and Inflammation
AK Agarwal |
Journal of Lipids | 2014 |
|
Molecular imaging of brown adipose tissue in health and disease
M Bauwens, R Wierts, B van Royen, J Bucerius, W Backes, F Mottaghy, B Brans |
European Journal of Nuclear Medicine and Molecular Imaging | 2014 |
|
Brown fat fuel utilization and thermogenesis
KL Townsend, YH Tseng |
Trends in Endocrinology & Metabolism | 2014 |
|
Dietary Fucoxanthin Increases Metabolic Rate and Upregulated mRNA Expressions of the PGC-1alpha Network, Mitochondrial Biogenesis and Fusion Genes in White Adipose Tissues of Mice
MT Wu, HN Chou, C Huang |
Marine drugs | 2014 |
|
The brown fat–enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis
GX Wang, XY Zhao, ZX Meng, M Kern, A Dietrich, Z Chen, Z Cozacov, D Zhou, AL Okunade, X Su, S Li, M Blüher, JD Lin |
Nature Medicine | 2014 |
|
What We Talk About When We Talk About Fat
ED Rosen, BM Spiegelman |
Cell | 2014 |
|
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers
A Loft, I Forss, MS Siersbæk, SF Schmidt, AS Larsen, JG Madsen, DF Pisani, R Nielsen, MM Aagaard, A Mathison, MJ Neville, R Urrutia, F Karpe, EZ Amri, S Mandrup |
Genes & development | 2014 |
|
The different shades of fat
V Peirce, S Carobbio, A Vidal-Puig |
Nature | 2014 |
|
Inhibition of the methionine aminopeptidase 2 enzyme for the treatment of obesity
AA Joharapurkar, NA Dhanesha, MR Jain |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy | 2014 |
|
Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat
Y Qiu, KD Nguyen, JI Odegaard, X Cui, X Tian, RM Locksley, RD Palmiter, A Chawla |
Cell | 2014 |
|
Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development
AC Daquinag, C Tseng, A Salameh, Y Zhang, F Amaya-Manzanares, A Dadbin, F Florez, Y Xu, Q Tong, MG Kolonin |
Cell Death and Differentiation | 2014 |
|
MicroRNA functions in brite/brown fat – novel perspectives towards anti-obesity strategies
M Karbiener, M Scheideler |
Computational and Structural Biotechnology Journal | 2014 |
|
Intermittent cold exposure enhances fat accumulation in mice
HS Yoo, L Qiao, C Bosco, LH Leong, N Lytle, GS Feng, NW Chi, J Shao |
PloS one | 2014 |
|
Reduced UCP-1 content in in vitro differentiated beige/brite adipocytes derived from preadipocytes of human subcutaneous white adipose tissues in obesity
AL Carey, C Vorlander, M Reddy-Luthmoodoo, AK Natoli, MF Formosa, DA Bertovic, MJ Anderson, SJ Duffy, BA Kingwell |
PloS one | 2014 |
|
A Long Noncoding RNA Transcriptional Regulatory Circuit Drives Thermogenic Adipocyte Differentiation
XY Zhao, S Li, GX Wang, Q Yu, JD Lin |
Molecular Cell | 2014 |
|
New Physiological Aspects of Brown Adipose Tissue
P Trayhurn, JR Arch |
Current Obesity Reports | 2014 |
|
GADD45 regulates the thermogenic capacity of brown adipose tissue
ML Gantner, BC Hazen, J Conkright, A Kralli |
Proceedings of the National Academy of Sciences | 2014 |
|
BMP7 Drives Human Adipogenic Stem Cells into Metabolically Active Beige Adipocytes
M Okla, JH Ha, RE Temel, S Chung |
Lipids | 2014 |
|
Detection of brown adipose tissue and thermogenic activity in mice by hyperpolarized xenon MRI
RT Branca, T He, L Zhang, CS Floyd, M Freeman, C White, A Burant |
Proceedings of the National Academy of Sciences | 2014 |
|
Insights into Brown Adipose Tissue Physiology as Revealed by Imaging Studies
C Izzi-Engbeaya, V Salem, RS Atkar, WS Dhillo |
Adipocyte | 2014 |
|
Is the heat surrounding adipose tissue mitochondria warranted?:
C Porter, I Malagaris, LS Sidossis |
Current Opinion in Clinical Nutrition and Metabolic Care | 2014 |
|
Cellular origins of cold-induced brown adipocytes in adult mice
YH Lee, AP Petkova, AA Konkar, JG Granneman |
The FASEB Journal | 2014 |
|
MRI detection of brown adipose tissue with low fat content in newborns with hypothermia
HH Hu, TW Wu, L Yin, MS Kim, JM Chia, TG Perkins, V Gilsanz |
Magnetic Resonance Imaging | 2014 |
|
Effect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in mice
Y Ravussin, C Xiao, O Gavrilova, ML Reitman |
PloS one | 2014 |
|
White-to-brown metabolic conversion of human adipocytes by JAK inhibition
A Moisan, YK Lee, JD Zhang, CS Hudak, CA Meyer, M Prummer, S Zoffmann, HH Truong, M Ebeling, A Kiialainen, R Gérard, F Xia, RT Schinzel, KE Amrein, CA Cowan |
Nature Cell Biology | 2014 |
|
Intraosseous hibernoma: characterization of five cases and literature review
SF Bonar, G Watson, C Gragnaniello, K Seex, J Magnussen, J Earwaker |
Skeletal Radiology | 2014 |
|
Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans
P Lee, JD Linderman, S Smith, RJ Brychta, J Wang, C Idelson, RM Perron, CD Werner, GQ Phan, US Kammula, E Kebebew, K Pacak, KY Chen, FS Celi |
Cell Metabolism | 2014 |
|
A combination of exercise and capsinoid supplementation additively suppresses diet-induced obesity by increasing energy expenditure in mice
K Ohyama, Y Nogusa, K Suzuki, K Shinoda, S Kajimura, M Bannai |
American journal of physiology. Endocrinology and metabolism | 2014 |
|
Adipose tissue browning and metabolic health
A Bartelt, J Heeren |
Nature Reviews Endocrinology | 2013 |
|
A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis
S Kajimura, M Saito |
Annual Review of Physiology | 2013 |
|
Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice
Y Okamatsu-Ogura, K Fukano, A Tsubota, A Uozumi, A Terao, K Kimura, M Saito |
PloS one | 2013 |
|
Impact of brown adipose tissue on body fatness and glucose metabolism in healthy humans
M Matsushita, T Yoneshiro, S Aita, T Kameya, H Sugie, M Saito |
International Journal of Obesity | 2013 |
|
Review: Evidence-based Clinical Research of Anti-obesity Supplements in Japan
A Yasueda, T Ito, K Maeda |
Immunology‚ Endocrine & Metabolic Agents in Medicinal Chemistry | 2013 |
|
Cold exposure increases brown adipose tissue in humans
C Greenhill |
Nature Reviews Endocrinology | 2013 |
|
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2011 |
|
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2011 |
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