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Citations to this article

Cellular pathophysiology of ischemic acute kidney injury
Joseph V. Bonventre, Li Yang
Joseph V. Bonventre, Li Yang
Published November 1, 2011
Citation Information: J Clin Invest. 2011;121(11):4210-4221. https://doi.org/10.1172/JCI45161.
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Science in Medicine Article has an altmetric score of 23

Cellular pathophysiology of ischemic acute kidney injury

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Abstract

Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here, we review the major components of this dynamic process, which involves hemodynamic alterations, inflammation, and endothelial and epithelial cell injury, followed by repair that can be adaptive and restore epithelial integrity or maladaptive, leading to chronic kidney disease. Better understanding of the cellular pathophysiological processes underlying kidney injury and repair will hopefully result in the design of more targeted therapies to prevent the injury, hasten repair, and minimize chronic progressive kidney disease.

Authors

Joseph V. Bonventre, Li Yang

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Total citations by year

Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2009 Total
Citations: 43 64 79 92 99 86 78 71 79 72 79 68 49 15 1 975
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Journal of the American Society of Nephrology : JASN 2024
Pax proteins mediate segment-specific functions in proximal tubule survival and response to ischemic injury
McElliott MC, Telang AC, Ference-Salo JT, Al-Suraimi A, Chowdhury M, Otto EA, Soofi A, Dressler GR, Beamish JA
American Journal of Physiology - Renal Physiology 2024
Tubular FoxP2 and Kidney Fibrosis
Zou Y, Yiu WH, Lok SW, Ma J, Feng Y, Lai KN, Tang SC
Journal of the American Society of Nephrology : JASN 2024
The Role of Mitochondrial AKT1 Signaling in Renal Tubular Injury of Metabolic Syndrome
Lin HY, Chen IY, Wang TM, Yen CH, Chen Y, Chen YH, Dai DF, Huang JF, Chiu YW, Yang MY
Kidney International Reports 2024
Integrins in the kidney - beyond the matrix.
Bock F, Li S, Pozzi A, Zent R
Nature reviews. Nephrology 2024
Involvement of necroptosıs and apoptosıs ın protectıve effects of cyclosporın a on ischemıa-reperfusıon injury in rat kıdney.
Ozgen ZE, Erdinc M, Kaya MS, Aktar F, Ozekinci SO, Erdinc L, Uyar E
Journal of molecular histology 2024
T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade
Kyungho Lee, Elizabeth Thompson, Sepideh Gharaie, Chirag Patel, Johanna T. Kurzhagen, Philip M Pierorazio, Lois Arend, Ajit Thomas, Sanjeev Noel, Barbara Slusher, Hamid Rabb
JCI Insight 2023
A renal epithelial G9a/FXR-CES1 axis benefits acute kidney injury by alleviating focal lipid accumulation
Dong Yang, Mingrui Xiong, Yu Fan, Yihao Zhou, Yuchen Chen, Xikai Liu, Qing Wang, yu zhang, Robert Petersen, Hua Su, Junqiu Yue, Chun Zhang, Hong Chen, Kun Huang, Ling Zheng
EMBO reports 2023
Radiotherapy Advances in Renal Disease—Focus on Renal Ischemic Preconditioning
Khbouz B, Gu S, Pinto Coelho T, Lallemand F, Jouret F
Bioengineering 2023
Toll-like Receptor 4 in Acute Kidney Injury
Vallés PG, Gil Lorenzo AF, Garcia RD, Cacciamani V, Benardon ME, Costantino VV
International journal of molecular sciences 2023
Diagnosis, pathophysiology and preventive strategies for cardiac surgery-associated acute kidney injury: a narrative review
Yu Y, Li C, Zhu S, Jin L, Hu Y, Ling X, Miao C, Guo K
European Journal of Medical Research 2023
XBP1 modulates endoplasmic reticulum and mitochondria crosstalk via regulating NLRP3 in renal ischemia/reperfusion injury
Ni H, Ou Z, Wang Y, Liu Y, Sun K, Zhang J, Zhang J, Deng W, Zeng W, Xia R, Xu J, Gong N, Miao Y
Cell Death Discovery 2023
Modeling Podocyte Ontogeny and Podocytopathies with the Zebrafish
Drummond BE, Ercanbrack WS, Wingert RA
Journal of Developmental Biology 2023
Enhancing the expression of a key mitochondrial enzyme at the inception of ischemia-reperfusion injury can boost recovery and halt the progression of acute kidney injury
Corridon PR
Frontiers in physiology 2023
Nanosystems for oxidative stress regulation in the anti-inflammatory therapy of acute kidney injury
Wang Y, Jiang H, Zhang L, Yao P, Wang S, Yang Q
Frontiers in Bioengineering and Biotechnology 2023
Concentrations and kinetics of renal biomarkers in dogs with gastric dilatation-volvulus with and without 24-h intravenous lidocaine
Lehmann A, Brunner A, Marti E, Francey T, Steinbach S, Peters LM, Adamik KN
Frontiers in Veterinary Science 2023
Renal Microcirculation Injury as the Main Cause of Ischemic Acute Kidney Injury Development
Kwiatkowska E, Kwiatkowski S, Dziedziejko V, Tomasiewicz I, Domański L
Biology 2023
Gray level co-occurrence matrix and wavelet analyses reveal discrete changes in proximal tubule cell nuclei after mild acute kidney injury.
Pantic I, Cumic J, Dugalic S, Petroianu GA, Corridon PR
Scientific Reports 2023
Deficiency of the Planar Cell Polarity Protein Intu Delays Kidney Repair and Suppresses Renal Fibrosis after Acute Kidney Injury
Wang S, Liu A, Su Y, Dong Z
The American Journal of Pathology 2023
Sterile Pancreas Inflammation during Preservation and after Transplantation
Kervella D, Mesnard B, Prudhomme T, Bruneau S, Masset C, Cantarovich D, Blancho G, Branchereau J
International journal of molecular sciences 2023
Systemic immune-inflammation index may predict the acute kidney injury and prognosis in patients with spontaneous cerebral hemorrhage undergoing craniotomy: a single-center retrospective study
Wang Q, Li S, Sun M, Ma J, Sun J, Fan M
BMC Nephrology 2023
Risperidone Administration Attenuates Renal Ischemia and Reperfusion Injury following Cardiac Arrest by Antiinflammatory Effects in Rats
Kim YH, Lee TK, Lee JC, Kim DW, Tae HJ, Park JH, Ahn JH, Lee CH, Won MH, Hong S
Veterinary Sciences 2023
Gene signature and prediction model of the mitophagy-associated immune microenvironment in renal ischemia-reperfusion injury
Chen RY, Li DW, Xie H, Liu XW, Zhuang SY, Wu HY, Wu JJ, Sun N, Qu JW, Miao JY, Zhong C, Huang YH, Yuan XD, Zhang M, Zhang WJ, Hou JQ
Frontiers in immunology 2023
p53 and Myofibroblast Apoptosis in Organ Fibrosis
McElhinney K, Irnaten M, O\u2019Brien C
International journal of molecular sciences 2023
Study protocol of a randomised, double-blind, placebo-controlled, two-arm parallel-group, multi-centre phase 3 pivotal trial to investigate the efficacy and safety of recombinant human alkaline phosphatase for treatment of patients with sepsis-associated acute kidney injury
Pickkers P, Angus DC, Arend J, Bellomo R, van den Berg E, Bernholz J, Bestle M, Broglio K, Carlsen J, Doig CJ, Ferrer R, Joannidis M, Francois B, Doi K, Kellum JA, Laterre PF, Liu K, Mehta RL, Murray PT, Ostermann M, Pettilä V, Richards S, Young P, Zarbock A, Kjølbye AL
BMJ Open 2023
Prognostic Value of the Red Blood Cell Distribution Width-to-Albumin Ratio in Critically Ill Older Patients with Acute Kidney Injury: A Retrospective Database Study
Guo L, Chen D, Cheng B, Gong Y, Wang B
Emergency Medicine International 2023
Renal ischemia-reperfusion injury in rabbits evaluated with quantitative susceptibility mapping: an animal study
Luo K, Yu A, Fu Q, Pan L, Dou W, Zhang J, Chen J
Quantitative imaging in medicine and surgery 2023
Salt-sensitive hypertension after reversal of unilateral ureteral obstruction
Imig JD, Khan MA, Stavniichuk A, Jankiewicz WK, Goorani S, Yeboah MM, El-Meanawy A
Biochemical Pharmacology 2023
Rac1 inhibition protects the kidney against kidney ischemia/reperfusion through the inhibition of macrophage migration
Park YR, Kong MJ, Noh MR, Park KM
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2023
Exploring the Metabolic Differences between Cisplatin- and UV Light-Induced Apoptotic Bodies in HK-2 Cells by an Untargeted Metabolomics Approach
Bernardo-Bermejo S, Sánchez-López E, Castro-Puyana M, Fernández-Martínez AB, Lucio-Cazaña FJ, Marina ML
International journal of molecular sciences 2023
Renal Disturbances during and after Radioligand Therapy of Neuroendocrine Tumors—Extended Analysis of Potential Acute and Chronic Complications
Saracyn M, Durma AD, Bober B, Lubas A, Kołodziej M, Kapusta W, Dmochowska B, Kamiński G
International journal of molecular sciences 2023
Free heme promotes acute kidney injury in transient renal ischemia
Robert Greite, Sebastian Schott, Li Wang, Lukas Gohlke, Kirill Kreimann, Katja Derlin, Marcel Gutberlet, Martina Schmidbauer, Andreas Leffler, Igor Tudorache, Jawad Salman, Fabio Ius, Ruslan Natanov, Christine Fegbeutel, Axel Haverich, Ralf Lichtinghagen, Anne Hüsing, Sibylle Vietinghoff, Roland Schmitt, Nelli Shushakova, Rong Song, Hermann Haller, Kai Schmidt-Ott, Magnus Gram, Vijith Vijayan, Irina Scheffner, Wilfried Gwinner, Stephan Immenschuh
Clinical and Translational Science 2023
Cyclic GMP–AMP Synthase (cGAS) Deletion Reduces Severity in Bilateral Nephrectomy Mice through Changes in Neutrophil Extracellular Traps and Mitochondrial Respiration
Suksawad N, Udompornpitak K, Thawinpipat N, Korwattanamongkol P, Visitchanakun P, Phuengmaung P, Saisorn W, Kueanjinda P, Leelahavanichkul A
Biomedicines 2023
Association between hyperuricemia and acute kidney injury in critically ill patients with sepsis.
Jiang YX, Gong CL, Tang Y, Yi Y, Liu FG, Zhou JW, Shi YL, Zhou HW, Xie KQ
BMC Nephrology 2023
Bibliometric and visualization analysis of kidney repair associated with acute kidney injury from 2002 to 2022.
Li J, Gong X
Frontiers in pharmacology 2023
Electric field-directed migration of mesenchymal stem cells enhances their therapeutic potential on cisplatin-induced acute nephrotoxicity in rats
Abdelrahman SA, Raafat N, Abdelaal GM, Aal SM
Naunyn-Schmiedeberg's Archives of Pharmacology 2023
Is Renal Ischemic Preconditioning an Alternative to Ameliorate the Short- and Long-Term Consequences of Acute Kidney Injury?
Ortega-Trejo JA, Bobadilla NA
International journal of molecular sciences 2023
Ischemic tubular injury: Oxygen-sensitive signals and metabolic reprogramming.
Rahbar Saadat Y, Hosseiniyan Khatibi SM, Sani A, Zununi Vahed S, Ardalan M
InflammoPharmacology 2023
MiR-21 alleviates renal tubular epithelial cells injury induced by ischemia by targeting TLR4.
Liu XJ, Lv JL, Zou X, Yu YY, Zhou HX, Wu Y, Geng YQ, Lie CH
Heliyon 2023
Acid-sensing ion channel 1a exacerbates renal ischemia-reperfusion injury through the NF-κB/NLRP3 inflammasome pathway.
Yang Y, Jin S, Zhang J, Chen W, Lu Y, Chen J, Yan Z, Shen B, Ning Y, Shi Y, Chen J, Wang J, Xu S, Jia P, Teng J, Fang Y, Song N, Ding X
Journal of Molecular Medicine 2023
Streptozotocin induces renal proximal tubular injury through p53 signaling activation.
Nakai K, Umehara M, Minamida A, Yamauchi-Sawada H, Sunahara Y, Matoba Y, Okuno-Ozeki N, Nakamura I, Nakata T, Yagi-Tomita A, Uehara-Watanabe N, Ida T, Yamashita N, Kamezaki M, Kirita Y, Konishi E, Yasuda H, Matoba S, Tamagaki K, Kusaba T
Scientific Reports 2023
Inflammatory mediators act at renal pericytes to elicit contraction of vasa recta and reduce pericyte density along the kidney medullary vascular network
Lilley RJ, Taylor KD, Wildman SS, Peppiatt-Wildman CM
Frontiers in physiology 2023
Naïve or Engineered Extracellular Vesicles from Different Cell Sources: Therapeutic Tools for Kidney Diseases
Ceccotti E, Saccu G, Herrera Sanchez MB, Bruno S
Pharmaceutics 2023
Effect of the Peptide Calcium Channel Blocker ω-hexatoxin-Hv1a on Cell Death during Ischemia/Reperfusion in vitro
Iurova EV, Beloborodov EA, Saenko YV, Sugak DE, Fomin AN, Slesarev SM, Pogodina YS
2023
Trajectories of systolic blood pressure decline in kidney transplant donors prior to circulatory death and delayed graft function.
Lin Y, Teixeira-Pinto A, Craig JC, Opdam H, Chapman JC, Pleass H, Carter A, Rogers NM, Davies CE, McDonald S, Yang J, Lim WH, Wong G
Clinical Kidney Journal 2023
Epigenetic modification in diabetic kidney disease
Liu Z, Liu J, Wang W, An X, Luo L, Yu D, Sun W
Frontiers in Endocrinology 2023
The Effects of Peroxisome Proliferator-Activated Receptor-Delta Modulator ASP1128 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.
van Till JWO, Nojima H, Kameoka C, Hayashi C, Sakatani T, Washburn TB, Molitoris BA, Shaw AD, Engelman DT, Kellum JA
Kidney International Reports 2023
Role of heparanase in sepsis‑related acute kidney injury (Review)
Li JC, Wang LJ, Feng F, Chen TT, Shi WG, Liu LP
Experimental and therapeutic medicine 2023
Amazonia Phytotherapy Reduces Ischemia and Reperfusion Injury in the Kidneys
de Oliveira BK, de Oliveira Silva E, Ventura S, Vieira GH, de Pina Victoria CD, Volpini RA, de Fátima Fernandes Vattimo M
Cells 2023
Clinical Prospect of Mesenchymal Stromal/Stem Cell-Derived Extracellular Vesicles in Kidney Disease: Challenges and the Way Forward
Kosanović M, Milutinović B, Kutzner TJ, Mouloud Y, Bozic M
Pharmaceutics 2023
CircTLK1 alleviates oxygen-glucose deprivation/reperfusion induced apoptosis in HK-2 cells through miR-136-5p/Bcl2 signal axis
Kuang L, Lu A, Yao S
Renal Failure 2023
The duration of acute kidney injury is an additional parameter to predict 1-year survival in very elderly patients
Li Q, Wang Y, Zhou F
2023
Activation of Angiopoietin-Tie2 Signaling Protects the Kidney from Ischemic Injury by Modulation of Endothelial-Specific Pathways
Li Y, Liu P, Zhou Y, Maekawa H, Silva JB, Ansari MJ, Boubes K, Alia Y, Deb DK, Thomson BR, Jin J, Quaggin SE
Journal of the American Society of Nephrology : JASN 2023
Identification of a selective SCoR2 inhibitor that protects against acute kidney injury
Zhou HL, Hausladen A, Anand P, Rajavel M, Stomberski CT, Zhang R, Premont RT, Greenlee WJ, van den Akker F, Stamler JS
Journal of Medicinal Chemistry 2023
miRNA155-5P participated in DDX3X targeted regulation of pyroptosis to attenuate renal ischemia/reperfusion injury.
Zhang Y, Lv X, Fan Q, Chen F, Wan Z, Nibaruta J, Wang H, Wang X, Yuan Y, Guo W, Leng Y
Aging 2023
Natural Products in Renal-Associated Drug Discovery.
Wruck W, Genfi AKA, Adjaye J
2023
Development of a Machine Learning Model of Postoperative Acute Kidney Injury Using Non-Invasive Time-Sensitive Intraoperative Predictors.
Zamirpour S, Hubbard AE, Feng J, Butte AJ, Pirracchio R, Bishara A
2023
Pannexin 1 targets mitophagy to mediate renal ischemia/reperfusion injury.
Su L, Zhang J, Wang J, Wang X, Cao E, Yang C, Sun Q, Sivakumar R, Peng Z
Communications biology 2023
Analysis of risk factors for severe acute kidney injury in patients with acute myocardial infarction: A retrospective study.
Nong Y, Wei X, Qiu H, Yang H, Yang J, Lu J, Cao J, Fu Y, Yu D
2023
The Therapeutic Potential of CDK4/6 Inhibitors, Novel Cancer Drugs, in Kidney Diseases.
Liang XB, Dai ZC, Zou R, Tang JX, Yao CW
International journal of molecular sciences 2023
Ferrostatin-1 post-treatment attenuates acute kidney injury in mice by inhibiting ferritin production and regulating iron uptake-related proteins
Zhao Y, Jiang B, Huang D, Lou J, Li G, Liu J, Duan F, Yuan Y, Su X
PeerJ 2023
Vitamin A and Retinoid Signaling in the Kidneys
DiKun K, Gudas LJ
Pharmacology & Therapeutics 2023
Salidroside inhibits renal ischemia/reperfusion injury‑induced ferroptosis by the PI3K/AKT signaling pathway
Tang Z, Wang Y, Liu Y, Li C
Experimental and therapeutic medicine 2023
The mechanism of ferroptosis and its related diseases
Feng S, Tang D, Wang Y, Li X, Bao H, Tang C, Dong X, Li X, Yang Q, Yan Y, Yin Z, Shang T, Zheng K, Huang X, Wei Z, Wang K, Qi S
2023
CD4+CD25+FOXP3+ regulatory T cells: a potential “armor” to shield “transplanted allografts” in the war against ischemia reperfusion injury
Jeyamogan S, Leventhal JR, Mathew JM, Zhang ZJ
Frontiers in immunology 2023
L-glutamine supplementation reduced morphological damage in the renal glomerulus of rats with Walker-256 tumor
Lima KR, Lopes ML, de Souza SR, Fracaro L, da Purificação NR, Lima MF, Lins LA, Lacchini S, de Araújo AA, de Araújo RF Júnior, Perles JV, Zanoni JN, Clebis NK
2023
Predictive value of perioperative procalcitonin, C reactive protein and high-sensitivity C reactive protein for the risk of postoperative complications after non-cardiac surgery in elderly patients: a nested case–control study
Chen Y, Zhao Y, Liu J, Teng Y, Ou M, Hao X
BMJ Open 2023
Novel PS-OME miRNA130b-3p Reduces Inflammation and Injury and Improves Survival after Renal Ischemia-Reperfusion Injury
Vazquez G, Sfakianos M, Coppa G, Jacob A, Wang P
Shock (Augusta, Ga.) 2023
Acute Kidney Injury by Ischemia/Reperfusion and Extracellular Vesicles
Nørgård MØ, Svenningsen P
International journal of molecular sciences 2023
Animal Models of Kidney Disease: Challenges and Perspectives
Liang J, Liu Y
2023
Knockout of the C3a receptor protects against renal ischemia reperfusion injury by reduction of NETs formation.
Wu X, You D, Pan M, Weng M, Xie Q, Guan Y, Zheng J, Lin S, Zhang X, Hao C, Wan J
Cellular and molecular life sciences : CMLS 2023
Development of an In Vitro Model for Inflammation Mediated Renal Toxicity Using 3D Renal Tubules and Co-Cultured Human Immune Cells.
Kyun ML, Park T, Jung H, Kim I, Kwon JI, Jeong SY, Choi M, Park D, Lee YB, Moon KS
Tissue Engineering and Regenerative Medicine 2023
Syndecan-1 shedding destroys epithelial adherens junctions through STAT3 after renal ischemia/reperfusion injury
Guo M, Shen D, Su Y, Xu J, Zhao S, Zhang W, Wang Y, Jiang W, Wang J, Geng X, Ding X, Xu X
iScience 2023
Comprehensive analysis of necroptosis-related genes in renal ischemia-reperfusion injury
Li S, Zhang W, Hu X
Frontiers in immunology 2023
Dynamics of necroptosis in kidney ischemia-reperfusion injury
Pefanis A, Bongoni AK, McRae JL, Salvaris EJ, Fisicaro N, Murphy JM, Ierino FL, Cowan PJ
Frontiers in immunology 2023
Mesenchymal stromal cells secretome restores bioenergetic and redox homeostasis in human proximal tubule cells after ischemic injury.
Faria J, Calcat-I-Cervera S, Skovronova R, Broeksma BC, Berends AJ, Zaal EA, Bussolati B, O'Brien T, Mihăilă SM, Masereeuw R
Stem Cell Research & Therapy 2023
Prion Protein Overexpression in Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Effectively Protected Rodent Kidney Against Ischemia-Reperfusion Injury Via Enhancing ATP/Mitochondrial Biogenesis—Role of ADMSC Rejuvenation and Proliferation
Chen YT, Yang CC, Chiang JY, Sung PH, Shao PL, Huang CR, Lee MS, Yip HK
Cell transplantation 2023
The role of N-methyladenosine modification in acute and chronic kidney diseases
Qi S, Song J, Chen L, Weng H
Molecular Medicine 2023
Dimethyl malonate preserves renal and mitochondrial functions following ischemia-reperfusion via inhibition of succinate dehydrogenase
Carlström M, Rannier Ribeiro Antonino Carvalho L, Guimaraes D, Boeder A, Schiffer TA
Redox Biology 2023
Extended pleurectomy/decortication and hyperthermic intraoperative intrapleural cisplatin perfusion for malignant pleural mesothelioma
Okubo K, Ishibashi H, Wakejima R, Baba S, Asakawa A, Seshima H
2023
Loss of nephric augmenter of liver regeneration facilitates acute kidney injury via ACSL4‐mediated ferroptosis
Huang L, Zhang L, Zhang Z, Tan F, Ma Y, Zeng X, Cao D, Deng L, Liu Q, Sun H, Shen B, Liao X
Journal of Cellular and Molecular Medicine 2023
Protective effects of limb remote ischemic per-conditioning on the heart injury induced by renal ischemic-reperfusion through the interaction of the apelin with the RAS/iNOS pathway
Janfeshan S, Masjedi F, Karimi Z
BioImpacts : BI 2023
Pax protein depletion in proximal tubules triggers conserved mechanisms of resistance to acute ischemic kidney injury preventing transition to chronic kidney disease
Beamish JA, Telang AC, McElliott MC, Al-Suraimi A, Chowdhury M, Ference-Salo JT, Otto EA, Menon R, Soofi A, Weinberg JM, Patel SR, Dressler GR
Kidney International 2023
Clinical findings, underlying pathogenetic processes and treatment of vascular dysfunction in autosomal dominant polycystic kidney disease
Zhu J, Liu F, Mao J
Renal Failure 2023
Physiology of Pregnancy-related Acute Kidney Injury
Moronge D, Sullivan JC, Faulkner JL
Comprehensive Physiology 2023
A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating AKT/mTOR-autophagy pathway
Xin Ouyang, Zhimei He, Heng Fang, Huidan Zhang, Fei Gao, Linhui Hu, Hao Yin, Qi Yin, Taofang Hao, Yating Hou, Qingrui Wu, Jia Deng, Jing Xu, Yirong Wang, Chunbo Chen
Molecular Therapy 2022
Temporal and sex-dependent gene expression patterns in a renal ischemia–reperfusion injury and recovery pig model
S Nemours, L Castro, D Ribatallada-Soriano, M Semidey, M Aranda, M Ferrer, A Sanchez, J Morote, G Cantero-Recasens, A Meseguer
Scientific Reports 2022
Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis
M Livingston, S Shu, Y Fan, Z Li, Q Jiao, X Yin, M Venkatachalam, Z Dong
Autophagy 2022
Sirtuin 7 Deficiency Reduces Inflammation and Tubular Damage Induced by an Episode of Acute Kidney Injury
A Sánchez-Navarro, M Martínez-Rojas, A Albarrán-Godinez, R Pérez-Villalva, J Auwerx, A de la Cruz, L Noriega, F Rosetti, N Bobadilla
International journal of molecular sciences 2022
ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury
Y Wang, M Zhang, R Bi, Y Su, F Quan, Y Lin, C Yue, X Cui, Q Zhao, S Liu, Y Yang, D Zhang, Q Cao, X Gao
Redox Biology 2022
Novel insights into NOD-like receptors in renal diseases
J Jin, T Zhou, G Ren, L Cai, X Meng
Acta Pharmacologica Sinica 2022
Molecular Mechanisms of Kidney Injury and Repair
S Rayego-Mateos, L Marquez-Expósito, R Rodrigues-Diez, A Sanz, R Guiteras, N Doladé, I Rubio-Soto, A Manonelles, S Codina, A Ortiz, J Cruzado, M Ruiz-Ortega, A Sola
International journal of molecular sciences 2022
Interleukin-22 in Renal Protection and Its Pathological Role in Kidney Diseases
Q Ma, J Luan, Y Bai, C Xu, F Liu, B Chen, D Ju, H Xu
Frontiers in immunology 2022
Macrophage-Specific MCPIP1/Regnase-1 Attenuates Kidney Ischemia-Reperfusion Injury by Shaping the Local Inflammatory Response and Tissue Regeneration
A Ribeiro, E Dobosz, M Krill, P Köhler, M Wadowska, S Steiger, C Schmaderer, J Koziel, M Lech
Cells 2022
Single-Nucleus Transcriptional Profiling of Chronic Kidney Disease after Cisplatin Nephrotoxicity
Z Ma, X Hu, H Ding, M Zhang, Y Huo, Z Dong
The American Journal of Pathology 2022
Extracellular Vesicles and Acute Kidney Injury: Potential Therapeutic Avenue for Renal Repair and Regeneration
M Kosanović, B Milutinovic, S Glamočlija, I Morlans, A Ortiz, M Bozic
International journal of molecular sciences 2022
Simultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury
K Mukherjee, C Gu, A Collins, M Mettlen, B Samelko, M Altintas, Y Sudhini, X Wang, R Bouley, D Brown, B Pedro, S Bane, V Gupta, P Brinkkoetter, H Hagmann, J Reiser, S Sever
Nature Communications 2022
Single Cell RNA Sequencing Identifies a Unique Inflammatory Macrophage Subset as a Druggable Target for Alleviating Acute Kidney Injury
W Yao, Y Chen, Z Li, J Ji, A You, S Jin, Y Ma, Y Zhao, J Wang, L Qu, H Wang, C Xiang, S Wang, G Liu, F Bai, L Yang
Advanced Science 2022
Unilateral Acute Renal Ischemia-Reperfusion Injury Induces Cardiac Dysfunction through Intracellular Calcium Mishandling
Junho CV, González-Lafuente L, Navarro-García JA, Rodríguez-Sánchez E, Carneiro-Ramos MS, Ruiz-Hurtado G
International journal of molecular sciences 2022
Extracellular Vesicles of Mesenchymal Stromal Cells Can be Taken Up by Microglial Cells and Partially Prevent the Stimulation Induced by β-amyloid
Kaniowska D, Wenk K, Rademacher P, Weiss R, Fabian C, Schulz I, Guthardt M, Lange F, Greiser S, Schmidt M, Braumann UD, Emmrich F, Koehl U, Jaimes Y
Stem Cell Reviews and Reports 2022
Maslinic Acid Attenuates Ischemia/Reperfusion-Induced Acute Kidney Injury by Suppressing Inflammation and Apoptosis Through Inhibiting NF-κB and MAPK Signaling Pathway
Sun W, Choi HS, Kim CS, Bae EH, Ma SK, Kim SW
Frontiers in pharmacology 2022
The Pathogenesis of Ischemia-Reperfusion Induced Acute Kidney Injury Depends on Renal Neutrophil Recruitment Whereas Sepsis-Induced AKI Does Not
Li Z, Ludwig N, Thomas K, Mersmann S, Lehmann M, Vestweber D, Pittet JF, Gomez H, Kellum JA, Rossaint J, Zarbock A
Frontiers in immunology 2022
Progress in Isoindolone Alkaloid Derivatives from Marine Microorganism: Pharmacology, Preparation, and Mechanism
Hang S, Chen H, Wu W, Wang S, Fang Y, Sheng R, Tu Q, Guo R
Marine drugs 2022
miRNA-486-5p: signaling targets and role in non-malignant disease
Douvris A, Viñas J, Burns KD
Cellular and Molecular Life Sciences 2022
5-Methyltetrahydrofolate Attenuates Oxidative Stress and Improves Kidney Function in Acute Kidney Injury through Activation of Nrf2 and Antioxidant Defense
Wijerathne CU, Au-Yeung KK, Siow YL, O K
Antioxidants 2022
Extracellular Vesicles Derived from Human Liver Stem Cells Attenuate Chronic Kidney Disease Development in an In Vivo Experimental Model of Renal Ischemia and Reperfusion Injury
Bruno S, Chiabotto G, Cedrino M, Ceccotti E, Pasquino C, De Rosa S, Grange C, Tritta S, Camussi G
International journal of molecular sciences 2022
Human Endothelial Progenitor Cells Protect the Kidney against Ischemia-Reperfusion Injury via the NLRP3 Inflammasome in Mice
Jang HN, Kim JH, Jung MH, Tak T, Jung JH, Lee S, Jung S, Chang SH, Kim HJ
International journal of molecular sciences 2022
Asymptomatic Hyperuricemia Promotes Recovery from Ischemic Organ Injury by Modulating the Phenotype of Macrophages
Gnemmi V, Li Q, Ma Q, De Chiara L, Carangelo G, Li C, Molina-Van den Bosch M, Romagnani P, Anders HJ, Steiger S
Cells 2022
Multidisciplinary basic and clinical research of acute kidney injury with COVID-19: Pathophysiology, mechanisms, incidence, management and kidney transplantation
Wishahi M, Kamal NM
World Journal of Nephrology 2022
More than a Marker: Arginase-1 in Kidney Repair
von Vietinghoff S, Schmitt R
Journal of the American Society of Nephrology : JASN 2022
Protective effects of asiaticoside on renal ischemia reperfusion injury in vivo and in vitro
Tang S, Xie X, Wang M, Yang L, Wei W
Bioengineered 2022
Rubicon-deficiency sensitizes mice to mixed lineage kinase domain-like (MLKL)-mediated kidney ischemia-reperfusion injury
Tonnus W, Locke S, Meyer C, Maremonti F, Eggert L, von Mässenhausen A, Bornstein SR, Green DR, Linkermann A
Cell Death and Disease 2022
Acute Kidney Injury in Critically-Ill COVID-19 Patients
Arrestier R, Gendreau S, Mokrani D, Bastard JP, Fellahi S, Bagate F, Masi P, d\u2019Humières T, Razazi K, Carteaux G, De Prost N, Audard V, Mekontso-Dessap A
Journal of Clinical Medicine 2022
Five-gene signature predicts acute kidney injury in early kidney transplant patients
Zhai X, Lou H, Hu J
Aging 2022
Modified chitosan for effective renal delivery of siRNA to treat acute kidney injury
Tang W, Jogdeo CM, Panja S, Tang S, Ding L, Yu A, Foster KW, Dsouza D, Chhonker YS, Jensen-Smith H, Jang HS, Boesen EI, Murry DJ, Padanilam B, Oupický D
Biomaterials 2022
The effects of two different dietary regimens during exercise on outcome of experimental acute kidney injury
Sabet N, Soltani Z, Khaksari M, Raji-Amirhasani A
Journal of inflammation (London, England) 2022
Nucleic Acid Nanotechnology for Diagnostics and Therapeutics in Acute Kidney Injury
Ying Y, Tang Q, Han D, Mou S
International journal of molecular sciences 2022
Inflammation-sensing catalase-mimicking nanozymes alleviate acute kidney injury via reversing local oxidative stress
Choi HS, Mathew AP, Uthaman S, Vasukutty A, Kim IJ, Suh SH, Kim CS, Ma SK, Graham SA, Kim SW, Park IK, Bae EH
Journal of nanobiotechnology 2022
Procalcitonin, Interleukin-6 and C-reactive Protein Levels Predict Renal Adverse Outcomes and Mortality in Patients with Acute Type A Aortic Dissection
Chen X, Zhou J, Fang M, Yang J, Wang X, Wang S, Yang L
Frontiers in Surgery 2022
A Single Oral Dose of Diclofenac Causes Transition of Experimental Subclinical Acute Kidney Injury to Chronic Kidney Disease
Störmer J, Gwinner W, Derlin K, Immenschuh S, Rong S, Jang MS, Shushakova N, Haller H, Gueler F, Greite R
Biomedicines 2022
Bryostatin-1 Attenuates Ischemia-Elicited Neutrophil Transmigration and Ameliorates Graft Injury after Kidney Transplantation
Becker F, Kebschull L, Rieger C, Mohr A, Heitplatz B, Van Marck V, Hansen U, Ansari J, Reuter S, Strücker B, Pascher A, Brockmann JG, Castor T, Alexander JS, Gavins FN
Cells 2022
Nanotechnology in Kidney and Islet Transplantation: An Ongoing, Promising Field
Wang W, Teng Y, Xue JJ, Cai HK, Pan YB, Ye XN, Mao XL, Li SW
Frontiers in immunology 2022
Specific bFGF targeting of KIM-1 in ischemic kidneys protects against renal ischemia-reperfusion injury in rats
Song S, Hou X, Zhang W, Liu X, Wang W, Wang X, Cao W, Xia Y, Chen W, Shi C
Regenerative Biomaterials 2022
Mecp2 protects kidney from ischemia-reperfusion injury through transcriptional repressing IL-6/STAT3 signaling
Wang J, Xiong M, Fan Y, Liu C, Wang Q, Yang D, Yuan Y, Huang Y, Wang S, Zhang Y, Niu S, Yue J, Su H, Zhang C, Chen H, Zheng L, Huang K
Theranostics 2022
Vitamin C Deficiency Causes Cell Type–Specific Epigenetic Reprogramming and Acute Tubular Necrosis in a Mouse Model
Yu Z, Xu Z, Liang Y, Yin P, Shi Y, Yu J, Hao J, Wang T, Ci W
Journal of the American Society of Nephrology : JASN 2022
Efficacy of umbilical cord mesenchymal stem cell transfusion for the treatment of severe AKI: a protocol for a randomised controlled trial
Yang Y, Gao J, Wang S, Wang W, Zhu FL, Wang X, Liang S, Feng Z, Lin S, Zhang L, Chen X, Cai G
BMJ Open 2022
Single nephron glomerular filtration rate measured by linescan multiphoton microscopy compared to conventional micropuncture
Costanzo V, D\u2019Apolito L, Sardella D, Iervolino A, La Manna G, Capasso G, Frische S, Trepiccione F
2022
Angiotensin (1–7) protects against renal ischemia-reperfusion injury via regulating expression of NRF2 and microRNAs in Fisher 344 rats
Zaman A, Banday AA
AJP Renal Physiology 2022
DUSP2-mediated inhibition of tubular epithelial cell pyroptosis confers nephroprotection in acute kidney injury
Xiong J, Ran L, Zhu Y, Wang Y, Wang S, Wang Y, Lan Q, Han W, Liu Y, Huang Y, He T, Li Y, Liu L, Zhao J, Yang K
Theranostics 2022
Effects of Dexmedetomidine Administered Through Different Routes on Kidney Tissue in Rats with Spinal Cord Ischaemia–Reperfusion Injury
Şengel N, Köksal Z, Dursun AD, Kurtipek Ö, Sezen ŞC, Arslan M, Kavutçu M
Drug design, development and therapy 2022
Interaction Between Intrinsic Renal Cells and Immune Cells in the Progression of Acute Kidney Injury
Deng J, Wu Z, He Y, Lin L, Tan W, Yang J
Frontiers in Medicine 2022
A novel eCIRP/TREM-1 pathway inhibitor attenuates acute kidney injury.
Siskind S, Royster W, Brenner M, Wang P
Surgery 2022
Ebselen ameliorates renal ischemia-reperfusion injury via enhancing autophagy in rats.
Wu Y, Shi H, Xu Y, Pei J, Song S, Chen W, Xu S
Molecular and Cellular Biochemistry 2022
Two independent modes of kidney stone suppression achieved by AIM/CD5L and KIM-1.
Matsuura K, Maehara N, Hirota A, Eguchi A, Yasuda K, Taniguchi K, Nishijima A, Matsuhashi N, Shiga Y, Ishii R, Iguchi Y, Tanabe K, Arai S, Miyazaki T
2022
Combining Clinical Parameters and Acute Tubular Injury Grading Is Superior in Predicting the Prognosis of Deceased-Donor Kidney Transplantation: A 7-Year Observational Study
Wang J, Liu J, Wu W, Yang S, Liu L, Fu Q, Li J, Chen X, Deng R, Wu C, Long S, Zhang W, Zhang H, Mao H, Chen W
Frontiers in immunology 2022
Control of Directed Cell Migration after Tubular Cell Injury by Nucleotide Signaling
Gessler S, Guthmann C, Schuler V, Lilienkamp M, Walz G, Yakulov TA
International journal of molecular sciences 2022
Exosome from indoleamine 2,3-dioxygenase-overexpressing bone marrow mesenchymal stem cells accelerates repair process of ischemia/reperfusion-induced acute kidney injury by regulating macrophages polarization
Xie X, Yang X, Wu J, Tang S, Yang L, Fei X, Wang M
Stem Cell Research & Therapy 2022
Circular RNAs in Acute Kidney Injury: Roles in Pathophysiology and Implications for Clinical Management
So BY, Yap DY, Chan TM
International journal of molecular sciences 2022
Mesenchymal Stem Cell-Derived Small Extracellular Vesicles: A Novel Approach for Kidney Disease Treatment
Lu Y, Wang L, Zhang M, Chen Z
International Journal of Nanomedicine 2022
Prediction of Mortality Risk After Ischemic Acute Kidney Injury With a Novel Prognostic Model: A Multivariable Prediction Model Development and Validation Study
Wang M, Yan P, Zhang NY, Deng YH, Luo XQ, Wang XF, Duan SB
Frontiers in Medicine 2022
Perioperative anemia predicts kidney injury after partial nephrectomy.
Li Q, Huang Y, Zhang L, Duan L, Qian S
Investigative and Clinical Urology 2022
Inhibition of the IRE1/JNK pathway in renal tubular epithelial cells attenuates ferroptosis in acute kidney injury.
Liang Y, Liu Z, Qu L, Wang Y, Zhou Y, Liang L, Guo Y, Tang L
Frontiers in pharmacology 2022
Candida Administration Worsens Neutrophil Extracellular Traps in Renal Ischemia Reperfusion Injury Mice: An Impact of Gut Fungi on Acute Kidney Injury
Saithong S, Saisorn W, Dang CP, Visitchanakun P, Chiewchengchol D, Leelahavanichkul A
Journal of Innate Immunity 2022
Urinary Collectrin (TMEM27) as Novel Marker for Acute Kidney Injury
Pajenda S, Wagner L, Gerges D, Herkner H, Tevdoradze T, Mechtler K, Schmidt A, Winnicki W
Life Sciences 2022
From AKI to CKD: Maladaptive Repair and the Underlying Mechanisms
Wang Z, Zhang C
International journal of molecular sciences 2022
Effects of Genistein on Common Kidney Diseases
Peng Q, Li Y, Shang J, Huang H, Zhang Y, Ding Y, Liang Y, Xie Z, Chen C
Nutrients 2022
LIGHT deficiency attenuates acute kidney disease development in an in vivo experimental renal ischemia and reperfusion injury model
Zheng QY, Li Y, Liang SJ, Chen XM, Tang M, Rao ZS, Li GQ, Feng JL, Zhong Y, Chen J, Xu GL, Zhang KQ
Cell Death Discovery 2022
Urinary NGAL, IGFBP-7, and TIMP-2: novel biomarkers to predict contrast medium-induced acute kidney injury in children
Sun Q, Kang Z, Li Z, Xun M
Renal Failure 2022
Extracellular CIRP induces acute kidney injury via endothelial TREM-1
Siskind S, Zhang F, Brenner M, Wang P
Frontiers in physiology 2022
Effects of Lycopene Attenuating Injuries in Ischemia and Reperfusion
Wu S, Guo X, Shang J, Li Y, Dong W, Peng Q, Xie Z, Chen C
Oxidative medicine and cellular longevity 2022
Different Acute Kidney Injury Patterns after Renal Ischemia Reperfusion Injury and Extracorporeal Membrane Oxygenation in Mice
Greite R, Störmer J, Gueler F, Khalikov R, Haverich A, Kühn C, Madrahimov N, Natanov R
International journal of molecular sciences 2022
Polyethylene glycol capped gold nanoparticles ameliorate renal ischemia–reperfusion injury in diabetic mice through AMPK-Nrf2 signaling pathway
Saleh H, Salama M, Hussein RM
Environmental Science and Pollution Research 2022
Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair.
Wang P, Huang Z, Peng Y, Li H, Lin T, Zhao Y, Hu Z, Zhou Z, Zhou W, Liu Y, Hou FF
Nature Communications 2022
Inhibition of Malate Dehydrogenase-2 Protects Renal Tubular Epithelial Cells from Anoxia-Reoxygenation-Induced Death or Senescence.
Eleftheriadis T, Pissas G, Golfinopoulos S, Efthymiadi M, Liakopoulos V, Stefanidis I
Biomolecules 2022
The Amomum tsao-ko Essential Oils Inhibited Inflammation and Apoptosis through p38/JNK MAPK Signaling Pathway and Alleviated Gentamicin-Induced Acute Kidney Injury.
Xu XJ, Zhang ML, Hou YM, Zhang K, Yao DH, Li GY, Kou WB, Wang HY, Wang JH
Molecules (Basel, Switzerland) 2022
Machine learning algorithm-based identification and verification of characteristic genes in acute kidney injury.
Li Y, Du Y, Zhang Y, Chen C, Zhang J, Zhang X, Zhang M, Yan Y
Frontiers in Medicine 2022
A senolysis-based theragnostic prodrug strategy towards chronic renal failure.
Song Y, Li X, Shi D, Sun T, Liu W, Li X, Qiao S, Chen X, Guo Y, Li J
Chemical Science 2022
A universal predictive and mechanistic urinary peptide signature in acute kidney injury
Piedrafita A, Siwy J, Klein J, Akkari A, Amaya-garrido A, Mebazaa A, Sanz AB, Breuil B, Montero Herrero L, Marcheix B, Depret F, Fernandez L, Tardif E, Minville V, Alves M, Metzger J, Grossac J, Mischak H, Ortiz A, Gazut S, Schanstra JP, Faguer S, Mayeur N, Casemayou A, Labaste F
Critical Care 2022
Correlation between coenzyme Q10 content and the nutrient sensors in AKI induced by Hemiscorpius lepturus envenomation
Dizaji R, Sharafi A, Pourahmad J, Vatanpour S, Dinmohammadi H, Vatanpour H, Hosseini MJ
BioImpacts : BI 2022
ROS-triggered endothelial cell death mechanisms: Focus on pyroptosis, parthanatos, and ferroptosis
Zheng D, Liu J, Piao H, Zhu Z, Wei R, Liu K
Frontiers in immunology 2022
Association of high-sensitivity C-reactive protein and anemia with acute kidney injury in neonates
Zhang P, Tong Y, Yuan D, Li Y, Jin Y, Bai L, Gao P, Wang W, Hu J, Duan X, Liu J
Frontiers in Pediatrics 2022
Low dimensional nanomaterials for treating acute kidney injury.
Nie Y, Wang L, You X, Wang X, Wu J, Zheng Z
Journal of nanobiotechnology 2022
The association between obesity and vitamin D deficiency modifies the progression of kidney disease after ischemia/reperfusion injury
Bernardo DR, Canale D, Nascimento MM, Shimizu MH, Seguro AC, de Bragança AC, Volpini RA
Frontiers in Nutrition 2022
Terlipressin combined with conservative fluid management attenuates hemorrhagic shock-induced acute kidney injury in rats
Castro LU, Otsuki DA, Sanches TR, Souza FL, Santinho MA, da Silva C, Noronha ID, Duarte-Neto AN, Gomes SA, Malbouisson LM, Andrade L
Scientific Reports 2022
Protective role of MG53 against ischemia/reperfusion injury on multiple organs: A narrative review
Xu B, Wang C, Chen H, Zhang L, Gong L, Zhong L, Yang J
Frontiers in physiology 2022
Histone Modifications in Acute Kidney Injury
Wang J, Shen F, Liu F, Zhuang S
Kidney Diseases 2022
TRPC Channels in the Physiology and Pathophysiology of the Renal Tubular System: What Do We Know?
Englisch CN, Paulsen F, Tschernig T
International journal of molecular sciences 2022
Brown-Norway chromosome 1 mitigates the upregulation of proinflammatory pathways in mTAL cells and subsequent age-related CKD in Dahl SS/JrHsdMcwi rats
Chivers JM, Whiles SA, Miles CB, Biederman BE, Ellison MF, Lovingood CW, Wright MH, Hoover DB, Raafey MA, Youngberg GA, Venkatachalam MA, Zheleznova NN, Yang C, Liu P, Kriegel AJ, Cowley AW, O\u2019Connor PM, Picken MM, Polichnowski AJ
AJP Renal Physiology 2022
Intestinal Microbiota in Experimental Acute Kidney Injury
Shah N, Rabb H
Nephron 2022
Exosomal transfer of microRNA-590-3p between renal tubular epithelial cells after renal ischemia-reperfusion injury regulates autophagy by targeting TRAF6
Chen Y, Zhang C, Du Y, Yang X, Liu M, Yang W, Lei G, Wang G
Chinese Medical Journal 2022
Definitions, phenotypes, and subphenotypes in acute kidney injury-Moving towards precision medicine.
Rodrigues CE, Endre ZH
Nephrology (Carlton, Vic.) 2022
Human scattered tubular cells represent a heterogeneous population of glycolytic dedifferentiated proximal tubule cells.
Eymael J, van den Broek M, Miesen L, Monge VV, van den Berge BT, Mooren F, Velez VL, Dijkstra J, Hermsen M, Bándi P, Vermeulen M, de Wildt S, Willemsen B, Florquin S, Wetzels R, Steenbergen E, Kramann R, Moeller M, Schreuder MF, Wetzels JF, van der Vlag J, Jansen J, Smeets B
The Journal of Pathology 2022
Does Omeprazole, the Proton-Pump Inhibitor, Affects the Structure of the Kidney of Male Albino Rats? Histological and Laboratory Study
Hussein HM, El-Nefiawy N, Hamid HF, Moneim MA
Journal of Microscopy and Ultrastructure 2022
When the Renal (Function) Begins to Fall: A Mini-Review of Acute Kidney Injury Related to Acute Respiratory Distress Syndrome in Critically Ill Patients.
Marchiset A, Jamme M
2022
Protective effect of fluoxetine against oxidative stress induced by renal ischemia-reperfusion injury via the regulation of miR-450b-5p/Nrf2 axis
Qin Z, Wang H, Dou Q, Xu L, Xu Z, Jia R
Aging 2022
An Overview of Ischemia–Reperfusion Injury: Review on Oxidative Stress and Inflammatory Response
Güler MC, Tanyeli A, Ekinci Akdemir FN, Eraslan E, Özbek Şebin S, Güzel Erdoğan D, Nacar T
The Eurasian Journal of Medicine 2022
The cellular landscape of the normal kidney allograft: Main players balancing the alloimmune response
McDaniels JM, Shetty AC, Rousselle TV, Bardhi E, Maluf DG, Mas VR
2022
Assessment of Kidney Proximal Tubular Secretion in Critical Illness
Pavan K. Bhatraju, Xin-Ya Chai, Neha A Sathe, John Ruzinski, Edward Siew, Jonathan Himmelfarb, Andrew N Hoofnagle, Mark M. Wurfel, Bryan R. Kestenbaum
JCI Insight 2021
Changes in NAD and Lipid Metabolism Drive Acidosis-Induced Acute Kidney Injury
M Bugarski, S Ghazi, M Polesel, JR Martins, AM Hall
Journal of the American Society of Nephrology : JASN 2021
Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury
H Zheng, Y Zhang, J He, Z Yang, R Zhang, L Li, Z Luo, Y Ye, Q Sun
Frontiers in immunology 2021
Aging modulates the effects of ischemic injury upon mesenchymal cells within the renal interstitium and microvasculature
IW Shaw, ED O'Sullivan, AO Pisco, G Borthwick, KM Gallagher, B Péault, J Hughes, DA Ferenbach
Stem Cells Translational Medicine 2021
Role of Macrophages and Related Cytokines in Kidney Disease
E Cantero-Navarro, S Rayego-Mateos, M Orejudo, L Tejedor-Santamaria, A Tejera-Muñoz, AB Sanz, L Marquez-Exposito, V Marchant, L Santos-Sanchez, J Egido, A Ortiz, T Bellon, RR Rodrigues-Diez, M Ruiz-Ortega
Frontiers in Medicine 2021
Exogenous hydrogen sulfide and miR-21 antagonism attenuates macrophage-mediated inflammation in ischemia reperfusion injury of the aged kidney
S Pushpakumar, S Kundu, G Weber, U Sen
GeroScience 2021
Role of Damage-Associated Molecular Patterns in Septic Acute Kidney Injury, From Injury to Recovery
PO Ludes, C de Roquetaillade, BG Chousterman, J Pottecher, A Mebazaa
Frontiers in immunology 2021
Shroom3, a Gene Associated with CKD, Modulates Epithelial Recovery after AKI
A Li, J Cunanan, H Khalili, T Plageman, K Ask, A Khan, A Hunjan, T Drysdale, D Bridgewater
2021
Targeting Premature Renal Aging: from Molecular Mechanisms of Cellular Senescence to Senolytic Trials
R Franzin, A Stasi, E Ranieri, GS Netti, V Cantaluppi, L Gesualdo, G Stallone, G Castellano
Frontiers in pharmacology 2021
Bioactive peptide apelin rescues acute kidney injury by protecting the function of renal tubular mitochondria
YM Guan, ZL Diao, HD Huang, JF Zheng, QD Zhang, LY Wang, WH Liu
Amino Acids 2021
FGF23 ameliorates ischemia-reperfusion induced acute kidney injury via modulation of endothelial progenitor cells: targeting SDF-1/CXCR4 signaling
HM Chang, KY Peng, CK Chan, CY Sun, YY Chen, HM Chang, CL Huang, PC Liu, PY Chen, KC Wang, WJ Wang, CC Wu, YF Lin, TS Lai, TM Huang, GH Young, SL Lin, M Ostermann, TS Chu, JS Chueh, VC Wu
Cell Death and Disease 2021
A potent truncated form of human soluble CR1 is protective in a mouse model of renal ischemia–reperfusion injury
AK Bongoni, IB Vikstrom, JL McRae, EJ Salvaris, N Fisicaro, MJ Pearse, S Wymann, T Rowe, AB Morelli, MP Hardy, PJ Cowan
Scientific Reports 2021
Acute Kidney Injury Induced Lupus Exacerbation Through the Enhanced Neutrophil Extracellular Traps (and Apoptosis) in Fcgr2b Deficient Lupus Mice With Renal Ischemia Reperfusion Injury
W Saisorn, S Saithong, P Phuengmaung, K Udompornpitak, T Bhunyakarnjanarat, P Visitchanakun, A Chareonsappakit, P Pisitkun, D Chiewchengchol, A Leelahavanichkul
Frontiers in immunology 2021
Therapeutic effects of stem cells in different body systems, a novel method that is yet to gain trust: A comprehensive review
A Ebrahimi, H Ahmadi, ZP Ghasrodashti, N Tanide, R Shahriarirad, A Erfani, K Ranjbar, S Ashkani-Esfahani
Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences 2021
Kidney toxicity of the BRAF-kinase inhibitor vemurafenib is driven by off-target ferrochelatase inhibition
Y Bai, JY Kim, B Bisunke, LA Jayne, JA Silvaroli, MS Balzer, M Gandhi, KM Huang, V Sander, J Prosek, RE Cianciolo, SD Baker, A Sparreboom, KD Jhaveri, K Susztak, A Bajwa, NS Pabla
Kidney International 2021
The Protective Effect of Anthocyanins Extracted from Aronia Melanocarpa Berry in Renal Ischemia-Reperfusion Injury in Mice
L Li, J Li, H Xu, F Zhu, Z Li, H Lu, J Zhang, Z Yang, Y Liu, TS Fröde
Mediators of Inflammation 2021
Mechanisms of Cisplatin-Induced Acute Kidney Injury: Pathological Mechanisms, Pharmacological Interventions, and Genetic Mitigations
KR McSweeney, LK Gadanec, T Qaradakhi, BA Ali, A Zulli, V Apostolopoulos
Cancers 2021
The Genomic Response to TGF-β1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney
CE Higgins, J Tang, SP Higgins, CC Gifford, BM Mian, DM Jones, W Zhang, A Costello, DJ Conti, R Samarakoon, PJ Higgins
Frontiers in Cell and Developmental Biology 2021
Renovascular effects of inorganic nitrate following ischemia-reperfusion of the kidney
G Zhang, H Han, Z Zhuge, F Dong, S Jiang, W Wang, DD Guimarães, TA Schiffer, EY Lai, LR Carvalho, RB Lucena, VA Braga, E Weitzberg, JO Lundberg, M Carlstrom
Redox Biology 2021
Multifaceted roles of Toll-like receptors in acute kidney injury
R Habib
Heliyon 2021
Tubular Cell Dropout in Preimplantation Deceased Donor Biopsies as a Predictor of Delayed Graft Function
ZM Avigan, N Singh, JA Kliegel, M Weiss, GW Moeckel, LG Cantley
Transplantation Direct 2021
Kidney-Targeted Delivery of Prolyl Hydroxylase Domain Protein 2 Small Interfering RNA with Nanoparticles Alleviated Renal Ischemia/Reperfusion Injury
D Xie, J Wang, G Hu, C Chen, H Yang, JK Ritter, Y Qu, N Li
The Journal of pharmacology and experimental therapeutics 2021
Deciphering the Role of Heme Oxygenase-1 (HO-1) Expressing Macrophages in Renal Ischemia-Reperfusion Injury
M Rossi, K Korpak, A Doerfler, KZ Boudjeltia
Biomedicines 2021
Increased vascular permeability and severe renal tubular damage after ischemia-reperfusion injury in mice lacking adiponectin or T-cadherin
Y Tsugawa-Shimizu, Y Fujishima, S Kita, S Minami, T Sakaue, Y Nakamura, T Okita, Y Kawachi, S Fukada, T Namba-Hamano, Y Takabatake, Y Isaka, H Nishizawa, B Ranscht, N Maeda, I Shimomura
American journal of physiology. Endocrinology and metabolism 2021
Renal Protective Effect of Beluga Lentil Pretreatment for Ischemia-Reperfusion Injury
S Lee, SY Chun, EH Lee, B Kim, BH Yoon, H Gil, DH Kim, BI Jang, DW Lee, ES Yoo, DJ Park, JN Lee, MH Han, BS Kim, PH Song, TG Kwon, YS Ha, D Monlezun
BioMed Research International 2021
Recombinant apoptosis inhibitor of macrophage protein reduces delayed graft function in a murine model of kidney transplantation
JY Lee, S Arumugarajah, D Lian, N Maehara, AR Haig, RS Suri, T Miyazaki, L Gunaratnam, P Mukhopadhyay
PloS one 2021
Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury
H Zheng, Y Zhang, L Li, R Zhang, Z Luo, Z Yang, Y Ye, J He, Q Sun
Frontiers in Cell and Developmental Biology 2021
Early type 1 diabetes aggravates renal ischemia/reperfusion-induced acute kidney injury
MC de Ponte, VG Cardoso, GL Gonçalves, JM Costa-Pessoa, M Oliveira-Souza
Scientific Reports 2021
Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury
M Ding, E Tolbert, M Birkenbach, R Gohh, F Akhlaghi, NS Ghonem
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2021
Loganin Attenuates Septic Acute Renal Injury with the Participation of AKT and Nrf2/HO-1 Signaling Pathways
J Zhang, C Wang, K Kang, H Liu, X Liu, X Jia, K Yu
Drug design, development and therapy 2021
Free Hemoglobin Ratio as a Novel Biomarker of Acute Kidney Injury After On-Pump Cardiac Surgery: Secondary Analysis of a Randomized Controlled Trial
J Hu, E Rezoagli, F Zadek, EA Bittner, C Lei, L Berra
Anesthesia & Analgesia 2021
Dual and Opposite Costimulatory Targeting with a Novel Human Fusion Recombinant Protein Effectively Prevents Renal Warm Ischemia Reperfusion Injury and Allograft Rejection in Murine Models
J Guiteras, LD Ramon, E Crespo, N Bolaños, S Barcelo-Batllori, L Martinez-Valenzuela, P Fontova, M Jarque, A Torija, O Bestard, D Resina, JM Grinyó, J Torras
International journal of molecular sciences 2021
Farnesoid X receptor promotes renal ischaemia‐reperfusion injury by inducing tubular epithelial cell apoptosis
Y Xu, D Li, J Wu, M Zhang, X Shao, L Xu, L Tang, M Zhu, Z Ni, M Zhang, S Mou
Cell Proliferation 2021
Vegfa promoter gene hypermethylation at HIF1α binding site is an early contributor to CKD progression after renal ischemia
A Sánchez-Navarro, R Pérez-Villalva, AR Murillo-de-Ozores, MÁ Martínez-Rojas, JR RodríguezAguilera, N González, M Castañeda-Bueno, G Gamba, F Recillas-Targa, NA Bobadilla
Scientific Reports 2021
Ultrasound enhances the therapeutic potential of mesenchymal stem cells wrapped in greater omentum for aristolochic acid nephropathy
Y Yang, X Geng, K Chi, C Liu, R Liu, X Chen, Q Hong, G Cai
Stem Cell Research & Therapy 2021
Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative
JR Prowle, LG Forni, M Bell, MS Chew, M Edwards, ME Grams, MP Grocott, KD Liu, D McIlroy, PT Murray, M Ostermann, A Zarbock, SM Bagshaw, R Bartz, S Bell, A Bihorac, TJ Gan, CE Hobson, M Joannidis, JL Koyner, DZ Levett, RL Mehta, TE Miller, MG Mythen, MK Nadim, RM Pearse, T Rimmele, C Ronco, AD Shaw, JA Kellum
Nature Reviews Nephrology 2021
Rapamycin Alternatively Modifies Mitochondrial Dynamics in Dendritic Cells to Reduce Kidney Ischemic Reperfusion Injury
M Namwanje, B Bisunke, TV Rousselle, GG Lamanilao, VS Sunder, EC Patterson, C Kuscu, C Kuscu, D Maluf, M Kiran, V Mas, JD Eason, A Bajwa
International journal of molecular sciences 2021
Harnessing the Physiological Functions of Cellular Prion Protein in the Kidneys: Applications for Treating Renal Diseases
S Yoon, G Go, Y Yoon, J Lim, G Lee, S Lee
Biomolecules 2021
Albumin Infusion in Critically Ill COVID-19 Patients: Hemodilution and Anticoagulation
G Ramadori
International journal of molecular sciences 2021
Postoperative 20% albumin vs standard care and acute kidney injury after high-risk cardiac surgery (ALBICS): study protocol for a randomised trial
M Balachandran, P Banneheke, A Pakavakis, W Al-Bassam, V Sarode, M Rowland, Y Shehabi
Trials 2021
Kidney Microcirculation as a Target for Innovative Therapies in AKI
B Ergin, S Akin, C Ince
Journal of Clinical Medicine 2021
Endothelial-Derived miR-17∼92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury
T Chiba, DM Cerqueira, Y Li, AJ Bodnar, E Mukherjee, K Pfister, YL Phua, K Shaikh, BT Sanders, SL Hemker, PJ Pagano, YL Wu, J Ho, S Sims-Lucas
Journal of the American Society of Nephrology : JASN 2021
Propofol ameliorates renal ischemia/reperfusion injury by enhancing macrophage M2 polarization through PPARγ/STAT3 signaling
Z Liu, Y Meng, Y Miao, L Yu, Q Wei, Y Li, B Zhang, Q Yu
Aging 2021
Lipotoxic Proximal Tubular Injury: A Primary Event in Diabetic Kidney Disease
H Wang, S Zhang, J Guo
Frontiers in Medicine 2021
Urinary Cyclophilin A as Marker of Tubular Cell Death and Kidney Injury
R Cabello, M Fontecha-Barriuso, D Martin-Sanchez, AM Lopez-Diaz, S Carrasco, I Mahillo, C Gonzalez-Enguita, MD Sanchez-Niño, A Ortiz, AB Sanz
Biomedicines 2021
High Throughput Proteomic Exploration of Hypothermic Preservation Reveals Active Processes within the Cell Associated with Cold Ischemia Kinetic
O Pasini-Chabot, J Vincent, SL Pape, M Lepoittevin, W Kaaki, JB Woillard, S Giraud, N Bourmeyster, T Hauet, R Thuillier
International journal of molecular sciences 2021
MicroRNA‑93 inhibits the apoptosis and inflammatory response of tubular epithelial cells via the PTEN/AKT/mTOR pathway in acute kidney injury
Y Zhan, M Zhu, S Liu, J Lu, Z Ni, H Cai, W Zhang
Molecular medicine reports 2021
Role of Circular RNA in Kidney-Related Diseases
XT Chen, ZW Li, X Zhao, ML Li, PF Hou, SF Chu, JN Zheng, J Bai
Frontiers in pharmacology 2021
An acute phase protein α1-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action
H Watanabe, R Fujimura, Y Hiramoto, R Murata, K Nishida, J Bi, T Imafuku, H Komori, H Maeda, A Mukunoki, T Takeo, N Nakagata, M Tanaka, K Matsushita, M Fukagawa, T Maruyama
Scientific Reports 2021
Astaxanthin protects against early acute kidney injury in severely burned rats by inactivating the TLR4/MyD88/NF-κB axis and upregulating heme oxygenase-1
S Guo, L Guo, Q Fang, M Yu, L Zhang, C You, X Wang, Y Liu, C Han
Scientific Reports 2021
Outcomes and risk management in type B aortic dissection patients with acute kidney injury: a concise review
X Chen, M Bai, S Sun, X Chen
Renal Failure 2021
Entacapone scavenges peroxynitrite and protects against kidney and liver injuries induced by renal ischemia/reperfusion in rats
E Soliman, SM Shewaikh, A Fahmy, S Elshazly
International Urology and Nephrology 2021
Pathophysiology and Clinical Manifestations of COVID-19-Related Acute Kidney Injury—The Current State of Knowledge and Future Perspectives
I Smarz-Widelska, E Grywalska, I Morawska, A Forma, A Michalski, S Mertowski, R Hrynkiewicz, P Niedźwiedzka-Rystwej, I Korona-Glowniak, M Parczewski, W Załuska
International journal of molecular sciences 2021
Acute Kidney Injury (AKI) before and after Kidney Transplantation: Causes, Medical Approach, and Implications for the Long-Term Outcomes
A Palmisano, I Gandolfini, M Delsante, C Cantarelli, E Fiaccadori, P Cravedi, U Maggiore
Journal of Clinical Medicine 2021
Xiaoyu Xiezhuo Drink Protects against Ischemia-Reperfusion Acute Kidney Injury in Aged Mice through Inhibiting the TGF-β1/Smad3 and HIF1 Signaling Pathways
Q Ye, H Chen, H Ma, X Xiang, S Hu, C Xia, L Fu, Z Jia
BioMed Research International 2021
Development and External Validation a Novel Inflammation-Based Score for Acute Kidney Injury and Prognosis in Intensive Care Unit Patients
J Wan, G Zou, B He, C Zhang, Y Zhu, L Yin, Z Lu
International journal of general medicine 2021
Genetic Susceptibility to Acute Kidney Injury
C Ortega-Loubon, P Martínez-Paz, E García-Morán, Á Tamayo-Velasco, FJ López-Hernández, P Jorge-Monjas, E Tamayo
Journal of Clinical Medicine 2021
The association of urine osmolality with decreased kidney function and/or albuminuria in the United States
BK Kitiwan, SM Vasunilashorn, HJ Baer, K Mukamal, SP Juraschek
BMC Nephrology 2021
Advances in Understanding of the Role of Lipid Metabolism in Aging
KW Chung
Cells 2021
Nicotinamide Mononucleotide Attenuates Renal Interstitial Fibrosis After AKI by Suppressing Tubular DNA Damage and Senescence
Y Jia, X Kang, L Tan, Y Ren, L Qu, J Tang, G Liu, S Wang, Z Xiong, L Yang
Frontiers in physiology 2021
Recombinant Long-Acting Thioredoxin Ameliorates AKI to CKD Transition via Modulating Renal Oxidative Stress and Inflammation
K Nishida, H Watanabe, R Murata, K Tokumaru, R Fujimura, S Oshiro, T Nagasaki, M Miyahisa, Y Hiramoto, H Nosaki, T Imafuku, H Maeda, M Fukagawa, T Maruyama
International journal of molecular sciences 2021
Pentraxin-3-mediated complement activation in a swine model of renal ischemia/reperfusion injury
C Divella, A Stasi, R Franzin, M Rossini, P Pontrelli, F Sallustio, GS Netti, E Ranieri, L Lacitignola, F Staffieri, AM Crovace, G Lucarelli, P Ditonno, M Battaglia, MR Daha, P van der Pol, C van Kooten, G Grandaliano, L Gesualdo, G Stallone, G Castellano
Aging 2021
Rationale and design of the Kidney Precision Medicine Project
IH de Boer, CE Alpers, EU Azeloglu, UG Balis, JM Barasch, L Barisoni, KN Blank, AS Bomback, K Brown, PC Dagher, AL Dighe, MT Eadon, TM El-Achkar, JP Gaut, N Hacohen, Y He, JB Hodgin, S Jain, JA Kellum, K Kiryluk, R Knight, ZG Laszik, C Lienczewski, LH Mariani, RL McClelland, S Menez, DG Moledina, SD Mooney, JF OToole, PM Palevsky, CR Parikh, ED Poggio, SE Rosas, MR Rosengart, MM Sarwal, JA Schaub, JR Sedor, K Sharma, B Steck, RD Toto, OG Troyanskaya, KR Tuttle, MA Vazquez, SS Waikar, K Williams, FP Wilson, K Zhang, R Iyengar, M Kretzler, J Himmelfarb, R Knight, S Lecker, I Stillman, S Waikar, G Mcmahon, A Weins, S Short, N Hacohen, P Hoover, M Aulisio, L Cooperman, L Herlitz, J OToole, E Poggio, J Sedor, S Jolly, P Appelbaum, O Balderes, J Barasch, A Bomback, PA Canetta, VD dAgati, K Kiryluk, S Kudose, K Mehl, J Radhakrishnan, C Weng, L Barisoni, T Alexandrov, T Ashkar, D Barwinska, P Dagher, K Dunn, M Eadon, M Ferkowicz, K Kelly, T Sutton, S Winfree, S Menez, C Parikh, A Rosenberg, P Villalobos, R Malik, D Fine, M Atta, JM Trujillo, A Slack, S Rosas, M Williams, E Azeloglu, CJ He, R Iyengar, J Hansen, S Parikh, B Rovin, C Anderton, L Pasa-Tolic, D Velickovic, J Lukowski, GH Oliver, J Ardayfio, J Bebiak, K Brown, T Campbell, C Campbell, L Hayashi, N Jefferson, R Koewler, G Roberts, J Saul, A Shpigel, EC Stutzke, L Wright, L Miegs, R Pinkeney, R Sealfon, O Troyanskaya, K Tuttle, D Dobi, Y Goltsev, B Lake, K Zhang, M Joanes, Z Laszik, A Schroeder, M Sarwal, T Sigdel, U Balis, V Blanc, O He, J Hodgin, M Kretzler, L Mariani, R Menon, E Otto, J Schaub, B Steck, C Lienczewski, S Eddy, Michele, D Hall, J Kellum, M Kruth, R Murugan, P Palevsky, P Randhawa, M Rosengart, S Sims-Lucas, M Stefanick, S Stull, M Tublin, C Alpers, I de Boer, A Dighe, J Himmelfarb, R Mcclelland, S Mooney, S Shankland, K Williams, K Blank, J Carson, F Dowd, Z Drager, C Park, K Sharma, G Zhang, S Bansal, M Venkatachalam, A Kermani, S Lee, C Lu, T Miller, O Moe, H Park, K Sambandam, F Sanchez, J Torrealba, T Robert, M Vazquez, N Wang, J Gaut, S Jain, A Vijayan, R Luciano, D Moledina, U Ugochukwu, FP Wilson, S Alfano
Kidney International 2021
Hypoxic mesenchymal stem cells ameliorate acute kidney ischemia-reperfusion injury via enhancing renal tubular autophagy
WC Tseng, PY Lee, MT Tsai, FP Chang, NJ Chen, CT Chien, SC Hung, DC Tarng
Stem Cell Research & Therapy 2021
Imaging the Renal Microcirculation in Cell Therapy
K Apelt, R Bijkerk, F Lebrin, TJ Rabelink
Cells 2021
Cumulative DNA damage by repeated low-dose cisplatin injection promotes the transition of acute to chronic kidney injury in mice
N Yamashita, K Nakai, T Nakata, I Nakamura, Y Kirita, S Matoba, BD Humphreys, K Tamagaki, T Kusaba
Scientific Reports 2021
Orphan nuclear receptor COUP‐TFII enhances myofibroblast glycolysis leading to kidney fibrosis
L Li, P Galichon, X Xiao, AC FigueroaRamirez, D Tamayo, JJ Lee, M Kalocsay, D GonzalezSanchez, MS Chancay, KW McCracken, NN Lee, T Ichimura, Y Mori, MT Valerius, J Wilflingseder, DR Lemos, ER Edelman, JV Bonventre
EMBO reports 2021
Diffusion Weighted Imaging and T2 Mapping Detect Inflammatory Response in the Renal Tissue during Ischemia Induced Acute Kidney Injury in Different Mouse Strains and Predict Renal Outcome
R Greite, K Derlin, D Hartung, R Chen, M Meier, M Gutberlet, B Hensen, F Wacker, F Gueler, S Hellms
Biomedicines 2021
Enhanced renoprotective effect of GDNF-modified adipose-derived mesenchymal stem cells on renal interstitial fibrosis
S Li, Y Wang, Z Wang, L Chen, B Zuo, C Liu, D Sun
Stem Cell Research & Therapy 2021
Silence of Long Noncoding RNA SNHG14 Alleviates Ischemia/Reperfusion-Induced Acute Kidney Injury by Regulating miR-124-3p/MMP2 Axis
Q Xue, L Yang, H Wang, S Han, K Ramoji
BioMed Research International 2021
The Protective Role of Prolyl Oligopeptidase (POP) Inhibition in Kidney Injury Induced by Renal Ischemia–Reperfusion
G Casili, A Ardizzone, R Basilotta, M Lanza, A Filippone, I Paterniti, E Esposito, M Campolo
International journal of molecular sciences 2021
Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury
JY Cao, B Wang, TT Tang, Y Wen, ZL Li, ST Feng, M Wu, D Liu, D Yin, KL Ma, RN Tang, QL Wu, HY Lan, LL Lv, BC Liu
Theranostics 2021
Klotho and Mesenchymal Stem Cells: A Review on Cell and Gene Therapy for Chronic Kidney Disease and Acute Kidney Disease
M Franco, S Beyerstedt, É Rangel
Pharmaceutics 2021
Renoprotective Role of Hypoxia-Inducible Factors and the Mechanism
Q Li, F Liu, X Tang, H Fu, J Mao
Kidney Diseases 2021
DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation
A Hishikawa, K Hayashi, A Kubo, K Miyashita, A Hashiguchi, K Kinouchi, N Yoshimoto, R Nakamichi, R Akashio, E Sugita, T Azegami, T Monkawa, M Suematsu, H Itoh
iScience 2021
Glucose Metabolism in Acute Kidney Injury and Kidney Repair
L Wen, Y Li, S Li, X Hu, Q Wei, Z Dong
Frontiers in Medicine 2021
High salt exacerbates acute kidney injury by disturbing the activation of CD5L/apoptosis inhibitor of macrophage (AIM) protein
CT Wang, T Tezuka, N Takeda, K Araki, S Arai, T Miyazaki, JA Joles
PloS one 2021
The Role of NLRP3 Inflammasome in Lupus Nephritis
CB Oliveira, CA Lima, G Vajgel, P Sandrin-Garcia
International journal of molecular sciences 2021
Exogenous Wnt1 Prevents Acute Kidney Injury and Its Subsequent Progression to Chronic Kidney Disease
Hong X, Zhou Y, Wang D, Lyu F, Guan T, Liu Y, Xiao L
Frontiers in physiology 2021
Treatment With Lisinopril Prevents the Early Progression of Glomerular Injury in Obese Dahl Salt-Sensitive Rats Independent of Lowering Arterial Pressure
Brown AK, Nichols A, Coley CA, Ekperikpe US, McPherson KC, Shields CA, Poudel B, Cornelius DC, Williams JM
Frontiers in physiology 2021
Renoprotective Potential of the Ultra-Pure Lipopolysaccharide from Rhodobacter Sphaeroides on Acutely Injured Kidneys in an Animal Model
Aal-Aaboda MS, Abu Raghif AR, Hadi NR
Archives of Razi Institute 2021
DAMPs Released From Injured Renal Tubular Epithelial Cells Activate Innate Immune Signals in Healthy Renal Tubular Epithelial Cells
DeWolf SE, Kasimsetty SG, Hawkes AA, Stocks LM, Kurian SM, McKay DB
Transplantation 2021
Determination of a microRNA signature of protective kidney ischemic preconditioning originating from proximal tubules
Khalid U, Jenkins RH, Andrews R, Pino-Chavez G, Cossins BC, Chavez R, Bowen T, Fraser DJ
Scientific Reports 2021
Anemia of cardiorenal syndrome
McCullough PA
Kidney International Supplements 2021
Role of indoleamine 2,3-dioxygenase in ischemia-reperfusion injury of renal tubular epithelial cells
Eleftheriadis T, Pissas G, Golfinopoulos S, Liakopoulos V, Stefanidis I
Molecular medicine reports 2021
Modelling and Prevention of Acute Kidney Injury through Ischemia and Reperfusion in a Combined Human Renal Proximal Tubule/Blood Vessel-on-a-Chip
Vormann MK, Tool LM, Ohbuchi M, Gijzen L, van Vught R, Hankemeier T, Kiyonaga F, Kawabe T, Goto T, Fujimori A, Vulto P, Lanz HL, Tetsuka K
2021
Surgical trauma is associated with renal immune cell activation in rats: A microarray study.
Hultström M, Peng D, Becirovic Agic M, Cupples CG, Cupples WA, Mitrou N
Physiological Reports 2021
Similarities and Differences between COVID-19-Associated Nephropathy and HIV-Associated Nephropathy.
Chen A, Yin L, Lee K, He JC
2021
Sustained local inhibition of thrombin preserves renal microarchitecture and function after onset of acute kidney injury
Vargas I, Stephenson DJ, Baldwin M, Gaut JP, Chalfant CE, Pan H, Wickline SA
Nanomedicine : nanotechnology, biology, and medicine 2021
Perioperative Perfusion of Allografts with Anti-Human T-lymphocyte Globulin Does Not Improve Outcome Post Liver Transplantation—A Randomized Placebo-Controlled Trial
Ritschl PV, Günther J, Hofhansel L, Ernst S, Ebner S, Sattler A, Weiß S, Weissenbacher A, Oberhuber R, Cardini B, Öllinger R, Biebl M, Denecke C, Margreiter C, Resch T, Schneeberger S, Maglione M, Kotsch K, Pratschke J
Journal of Clinical Medicine 2021
Ischemic Reperfusion Injury and AKI: Role for Mitochondrial Therapy
Pabla N, Bajwa A
Nephron 2021
Effect of Lipopolysaccharide from Rhodobacter sphaeroides on Inflammatory Pathway and Oxidative Stress in Renal Ischemia/Reperfusion Injury in Male Rats
Aal-Aaboda M, Abu Raghif AR, Hadi NR
Archives of Razi Institute 2021
The incidence, risk, presentation, pathophysiology, treatment, and effects of perioperative acute kidney injury
Billings FT IV, Lopez MG, Shaw AD
2021
Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury
Li L, Liu S, Zhou Y, Zhao M, Wang Y, Wang C, Lou P, Huang R, Ma L, Lu Y, Fu P, Liu J
Journal of Cellular and Molecular Medicine 2021
Effects of Lipoic Acid on Ischemia-Reperfusion Injury
Ding Y, Zhang Y, Zhang W, Shang J, Xie Z, Chen C
Oxidative medicine and cellular longevity 2021
The Role of Indoleamine 2,3-Dioxygenase in Renal Tubular Epithelial Cells Senescence under Anoxia or Reoxygenation
Eleftheriadis T, Pissas G, Filippidis G, Liakopoulos V, Stefanidis I
Biomolecules 2021
Usefulness of Contrast-enhanced Ultrasound in the Evaluation of Chronic Kidney Disease
Han BH, Park SB
2021
Conivaptan and Boric Acid Treatments in Acute Kidney Injury: Is This Combination Effective and Safe?
Can B, Kar F, Kar E, Özkoç M, Şentürk H, Dönmez DB, Kanbak G, Alataş İÖ
Biological Trace Element Research 2021
Renal Tubular Handling of Glucose and Fructose in Health and Disease
Vallon V, Nakagawa T
Comprehensive Physiology 2021
Pro-inflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice
Maria Agustina Battistone, Alexandra C. Mendelsohn, Raul German Spallanzani, Andrew S. Allegretti, Rachel N. Liberman, Juliana Sesma, Sahir Kalim, Susan M. Wall, Joseph V. Bonventre, Eduardo R. Lazarowski, Dennis Brown, Sylvie Breton
Journal of Clinical Investigation 2020
Immune cell landscaping reveals a protective role for Tregs during kidney injury and fibrosis
Fernanda V Duraes, Armelle Lafont, Martin Beibel, Kea Martin, Katy Darribat, Rachel Cuttat-Theurillat, Annick Waldt, Ulrike Naumann, Grazyna Wieczorek, Swann Gaulis, Sabina Pfister, Kirsten D. Mertz, Jianping Li, Guglielmo Roma, Max Warncke
JCI Insight 2020
Regeneration after acute kidney injury requires PTIP mediated epigenetic modifications.
Abdul Soofi, Ana P. Kutschat, Mohammad Azam, Ann Laszczyk, Greg Dressler
JCI Insight 2020
Tubular mitochondrial AKT1 is activated during ischemia reperfusion injury and has a critical role in predisposition to chronic kidney disease
HY Lin, Y Chen, YH Chen, AP Ta, HC Lee, GR MacGregor, ND Vaziri, PH Wang
Kidney International 2020
Protein Kinase C- δ Mediates Kidney Tubular Injury in Cold Storage–Associated Kidney Transplantation
J Zhu, G Zhang, Z Song, X Xiang, S Shu, Z Liu, D Yang, Q Wei, Z Dong
Journal of the American Society of Nephrology : JASN 2020
Glucose transporters in the kidney in health and disease
V Vallon
Pflügers Archiv - European Journal of Physiology 2020
miR-214 represses mitofusin-2 to promote renal tubular apoptosis in ischemic acute kidney injury
Y Yan, Z Ma, J Zhu, M Zeng, H Liu, Z Dong
American journal of physiology. Renal physiology 2020
MiR-181d-5p Targets KLF6 to Improve Ischemia/Reperfusion-Induced AKI Through Effects on Renal Function, Apoptosis, and Inflammation
Y Zhang, C Li, C Guan, B Zhou, L Wang, C Yang, L Zhen, J Dai, L Zhao, W Jiang, Y Xu
Frontiers in physiology 2020
Ischemia and Reperfusion Injury in Kidney Transplantation: Relevant Mechanisms in Injury and Repair
GJ Nieuwenhuijs-Moeke, SE Pischke, SP Berger, JS Sanders, RA Pol, MM Struys, RJ Ploeg, HG Leuvenink
Journal of Clinical Medicine 2020
Inflammaging and Complement System: A Link Between Acute Kidney Injury and Chronic Graft Damage
R Franzin, A Stasi, M Fiorentino, G Stallone, V Cantaluppi, L Gesualdo, G Castellano
Frontiers in immunology 2020
miR-182-5p and miR-378a-3p regulate ferroptosis in I/R-induced renal injury
C Ding, X Ding, J Zheng, B Wang, Y Li, H Xiang, M Dou, Y Qiao, P Tian, W Xue
Cell Death and Disease 2020
Role of chemokines, innate and adaptive immunity
KA Zimmerman, K Hopp, M Mrug
Cellular Signalling 2020
FTY720 Regulates Mitochondria Biogenesis in Dendritic Cells to Prevent Kidney Ischemic Reperfusion Injury
TV Rousselle, C Kuscu, C Kuscu, K Schlegel, LP Huang, M Namwanje, JD Eason, L Makowski, D Maluf, V Mas, A Bajwa
Frontiers in immunology 2020
A long journey for acute kidney injury biomarkers
DJ Oh
Renal Failure 2020
Protective role of endothelial calpain knockout in lipopolysaccharide-induced acute kidney injury via attenuation of the p38-iNOS pathway and NO/ROS production
Z Liu, J Ji, D Zheng, L Su, T Peng, J Tang
Experimental & molecular medicine 2020
A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury
JY Kim, Y Bai, LA Jayne, RD Hector, AK Persaud, SS Ong, S Rojesh, R Raj, MJ Feng, S Chung, RE Cianciolo, JW Christman, MJ Campbell, DS Gardner, SD Baker, A Sparreboom, R Govindarajan, H Singh, T Chen, M Poi, K Susztak, SR Cobb, NS Pabla
Nature Communications 2020
SOX9 promotes stress-responsive transcription of VGF nerve growth factor inducible gene in renal tubular epithelial cells
JY Kim, Y Bai, LA Jayne, F Abdulkader, M Gandhi, T Perreau, SV Parikh, DS Gardner, AJ Davidson, V Sander, MA Song, A Bajwa, NS Pabla
The Journal of biological chemistry 2020
FGF/FGFR2 Protects against Tubular Cell Death and Acute Kidney Injury Involving Erk1/2 Signaling Activation
Z Xu, X Zhu, M Wang, Y Lu, C Dai
Kidney Diseases 2020
Increased fibrotic signaling in a murine model for intra-arterial contrast-induced acute kidney injury
A Sharma, S Kilari, C Cai, ML Simeon, S Misra
American journal of physiology. Renal physiology 2020
Human amniotic epithelial cells ameliorate kidney damage in ischemia-reperfusion mouse model of acute kidney injury
Y Ren, Y Chen, X Zheng, H Wang, X Kang, J Tang, L Qu, X Shao, S Wang, S Li, G Liu, L Yang
Stem Cell Research & Therapy 2020
Recent Advances in the Role of Natural Killer Cells in Acute Kidney Injury
C Cantoni, S Granata, M Bruschi, GM Spaggiari, G Candiano, G Zaza
Frontiers in immunology 2020
Toll-Like Receptor as a Potential Biomarker in Renal Diseases
S Mertowski, P Lipa, I Morawska, P Niedźwiedzka-Rystwej, D Bębnowska, R Hrynkiewicz, E Grywalska, J Roliński, W Załuska
International journal of molecular sciences 2020
Extracellular vesicle–encapsulated IL-10 as novel nanotherapeutics against ischemic AKI
TT Tang, B Wang, M Wu, ZL Li, Y Feng, JY Cao, D Yin, H Liu, RN Tang, SD Crowley, LL Lv, BC Liu
Science Advances 2020
Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases
W Zhang, X Li, S Wang, Y Chen, H Liu
Cell Death Discovery 2020
Autophagy and Autophagy-Related Diseases: A Review
T Ichimiya, T Yamakawa, T Hirano, Y Yokoyama, Y Hayashi, D Hirayama, K Wagatsuma, T Itoi, H Nakase
International journal of molecular sciences 2020
Salusin-β mediates tubular cell apoptosis in acute kidney injury: Involvement of the PKC/ROS signaling pathway
QB Lu, Q Du, HP Wang, ZH Tang, YB Wang, HJ Sun
Redox Biology 2020
SerpinB2 Regulates Immune Response in Kidney Injury and Aging
P Sen, A Helmke, CM Liao, I Sörensen-Zender, S Rong, JH Bräsen, A Melk, H Haller, S von Vietinghoff, R Schmitt
Journal of the American Society of Nephrology : JASN 2020
LncRNA GAS5 promotes apoptosis as a competing endogenous RNA for miR-21 via thrombospondin 1 in ischemic AKI
X Geng, N Song, S Zhao, J Xu, Y Liu, Y Fang, M Liang, X Xu, X Ding
Cell Death Discovery 2020
Synergistic renoprotective effects of sesame oil and erythropoietin on ischemic kidney injury after renal transplantation
L Ye, F Xiao, J Xie, L Feng, Z Tang, E Chen, C Chen, B Xu, R Deng
AMB Express 2020
Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury
J Liu, S Kumar, A Heinzel, M Gao, J Guo, GF Alvarado, R Reindl-Schwaighofer, AM Krautzberger, PE Cippà, J McMahon, R Oberbauer, AP McMahon
Journal of the American Society of Nephrology : JASN 2020
Lactoferrin Contributes a Renoprotective Effect in Acute Kidney Injury and Early Renal Fibrosis
YH Hsu, IJ Chiu, YF Lin, YJ Chen, YH Lee, HW Chiu
Pharmaceutics 2020
Pharmacologic targeting of renal ischemia-reperfusion injury using a normothermic machine perfusion platform
AM Hameed, DB Lu, H Burns, N Byrne, YV Chew, S Julovi, K Ghimire, NT Zanjani, CH Png, D Meijles, S Dervish, R Matthews, R Miraziz, G OGrady, L Yuen, HC Pleass, NM Rogers, WJ Hawthorne
Scientific Reports 2020
Ten-eleven translocation methyl-cytosine dioxygenase 2 deficiency exacerbates renal ischemia-reperfusion injury
H Yan, L Tan, Y Liu, N Huang, J Cang, H Wang
Clinical Epigenetics 2020
Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury
J Wilflingseder, M Willi, HK Lee, H Olauson, J Jankowski, T Ichimura, R Erben, MT Valerius, L Hennighausen, JV Bonventre
Nature Communications 2020
XJB-5-131 inhibited ferroptosis in tubular epithelial cells after ischemia−reperfusion injury
Z Zhao, J Wu, H Xu, C Zhou, B Han, H Zhu, Z Hu, Z Ma, Z Ming, Y Yao, R Zeng, G Xu
Cell Death and Disease 2020
Dyslipidemia in Kidney Disorders: Perspectives on Mitochondria Homeostasis and Therapeutic Opportunities
PH Lin, P Duann
Frontiers in physiology 2020
An Uromodulin mutation drives autoimmunity and kidney mononuclear phagocyte endoplasmic reticulum stress
M Plotkin, CA OBrien, J Goellner, J Williams, W Carter, S Sharma, A Stone
The American Journal of Pathology 2020
Autophagy Dynamics and Modulation in a Rat Model of Renal Ischemia-Reperfusion Injury
JP Decuypere, S Hutchinson, D Monbaliu, W Martinet, J Pirenne, I Jochmans
International journal of molecular sciences 2020
The Many Faces of Matrix Metalloproteinase-7 in Kidney Diseases
Z Liu, RJ Tan, Y Liu
Biomolecules 2020

Intermedin Alleviates Renal Ischemia-Reperfusion Injury and Enhances Neovascularization in Wistar Rats


Y Wang, Y Mi, J Tian, , X Su, J Kang, Z Wu, G Wang, X Zhou, Y Zhou, R Li
Drug design, development and therapy 2020
Activation of aryl hydrocarbon receptor by 6‐formylindolo[3,2‐b]carbazole alleviated acute kidney injury by repressing inflammation and apoptosis
S Tao, F Guo, Q Ren, J Liu, T Wei, L Li, L Ma, P Fu
Journal of Cellular and Molecular Medicine 2020
Repurposing of metformin and colchicine reveals differential modulation of acute and chronic kidney injury
M El-Rashid, D Nguyen-Ngo, N Minhas, DN Meijles, J Li, K Ghimire, S Julovi, NM Rogers
Scientific Reports 2020
Gene knockout of the Na + -glucose cotransporter SGLT2 in a murine model of acute kidney injury induced by ischemia-reperfusion
J Nespoux, R Patel, H Zhang, W Huang, B Freeman, PW Sanders, YC Kim, V Vallon
American journal of physiology. Renal physiology 2020
Irisin Pretreatment Protects Kidneys against Acute Kidney Injury Induced by Ischemia/Reperfusion via Upregulating the Expression of Uncoupling Protein 2
R Zhang, J Ji, X Zhou, R Li
BioMed Research International 2020
Hyperbaric oxygen preconditioning and the role of NADPH oxidase inhibition in postischemic acute kidney injury induced in spontaneously hypertensive rats
S Kovacevic, M Ivanov, Z Miloradovic, P Brkic, UJ Vajic, M Zivotic, N Mihailovic-Stanojevic, D Jovovic, D Karanovic, R Jeremic, J Nesovic-Ostojic, M Bader
PloS one 2020
MFG-E8-derived peptide attenuates inflammation and injury after renal ischemia-reperfusion in mice
J Last, M Brenner, HT Yen, M Aziz, NL Denning, P Wang
Heliyon 2020
Inhibition of 15-PGDH prevents ischemic renal injury by the PGE 2 /EP 4 signaling pathway mediating vasodilation, increased renal blood flow, and increased adenosine/A 2A receptors
HJ Kim, SH Kim, M Kim, HJ Baik, SJ Park, MS Kang, DH Kim, BW Kim, SD Markowitz, KB Bae
American journal of physiology. Renal physiology 2020
Fibroblast Growth Factor 10 Attenuates Renal Damage by Regulating Endoplasmic Reticulum Stress After Ischemia–Reperfusion Injury
X Tan, L Yu, R Yang, Q Tao, L Xiang, J Xiao, JS Zhang
Frontiers in pharmacology 2020
Kidney Perfusion as an Organ Quality Assessment Tool—Are We Counting Our Chickens Before They Have Hatched?
JD Beule, I Jochmans
Journal of Clinical Medicine 2020
A Machine Learning-Based Prediction of Hospital Mortality in Patients With Postoperative Sepsis
R Yao, X Jin, G Wang, Y Yu, G Wu, Y Zhu, L Li, Y Li, P Zhao, S Zhu, Z Xia, C Ren, Y Yao
Frontiers in Medicine 2020
miR-195-5p alleviates acute kidney injury through repression of inflammation and oxidative stress by targeting vascular endothelial growth factor A
Y Xu, W Jiang, L Zhong, H Li, L Bai, X Chen, Y Lin, D Zheng
Aging 2020
CD154 Induces Interleukin-6 Secretion by Kidney Tubular Epithelial Cells under Hypoxic Conditions: Inhibition by Chloroquine
A Dewitte, J Villeneuve, S Lepreux, M Bouchecareilh, X Gauthereau, C Rigothier, C Combe, A Ouattara, J Ripoche
Mediators of Inflammation 2020
A visual risk assessment tool for acute kidney injury after intracranial aneurysm clipping surgery
P Zhang, C Guan, C Li, Z Zhu, W Zhang, H Luan, B Zhou, X Man, L Che, Y Wang, L Zhao, H Zhang, C Luo, Y Xu
Renal Failure 2020
Endothelial Dysfunction is Associated With Increased Incidence, Worsened Severity, and Prolonged Duration of Acute Kidney Injury After Severe Trauma
GE Hatton, KD Isbell, HH Henriksen, J Stensballe, M Brummerstedt, PI Johansson, LS Kao, CE Wade
Shock 2020
Protection of the transplant kidney during cold perfusion with doxycycline: proteomic analysis in a rat model
MA Moser, K Sawicka, J Sawicka, A Franczak, A Cohen, I Bil-Lula, G Sawicki
Proteome Science 2020
Independent risk factors and the long-term outcomes for postoperative continuous renal replacement treatment in patients who underwent emergency surgery for type a acute aortic dissection
Z Wang, M Ge, T Chen, C Chen, Q Zong, L Lu, D Wang
Journal of Cardiothoracic Surgery 2020
Genetic Deletion of Vasohibin-2 Exacerbates Ischemia-Reperfusion-Induced Acute Kidney Injury
H Miyake, K Tanabe, S Tanimura, Y Nakashima, T Morioka, K Masuda, H Sugiyama, Y Sato, J Wada
International journal of molecular sciences 2020
SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model
J Jiang, B Hu, CS Chung, Y Chen, Y Zhang, EW Tindal, J Li, A Ayala
Molecular Medicine 2020
Post-Ischemic Renal Fibrosis Progression Is Halted by Delayed Contralateral Nephrectomy: The Involvement of Macrophage Activation
P Tod, EN Bukosza, B Róka, T Kaucsár, A Fintha, T Krenács, G Szénási, P Hamar
International journal of molecular sciences 2020
Meprin-β activity modulates the β-catalytic subunit of protein kinase A in ischemia-reperfusion-induced acute kidney injury
F Ahmed, JM Mwiza, M Fernander, I Yahaya, S Abousaad, EM Ongeri
American journal of physiology. Renal physiology 2020
Effects of low versus standard pressure pneumoperitoneum on renal syndecan-1 shedding and VEGF receptor-2 expression in living-donor nephrectomy: a randomized controlled study
D Aditianingsih, CA Mochtar, A Lydia, NC Siregar, NI Margyaningsih, AS Madjid, S Suwarto
BMC Anesthesiology 2020
Effective Nephroprotection Against Acute Kidney Injury with a Star-Shaped Polyglutamate-Curcuminoid Conjugate
G Córdoba-David, A Duro-Castano, RC Castelo-Branco, C González-Guerrero, P Cannata, AB Sanz, MJ Vicent, A Ortiz, AM Ramos
Scientific Reports 2020
Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation
K Kreimann, MS Jang, S Rong, R Greite, S von Vietinghoff, R Schmitt, JH Bräsen, L Schiffer, J Gerstenberg, V Vijayan, O Dittrich-Breiholz, L Wang, CM Karsten, W Gwinner, H Haller, S Immenschuh, F Gueler
Frontiers in immunology 2020
Endothelin-1 Mediates the Systemic and Renal Hemodynamic Effects of GPR81 Activation
NK Jones, K Stewart, A Czopek, RI Menzies, A Thomson, CM Moran, C Cairns, BR Conway, L Denby, DE Livingstone, J Wiseman, PW Hadoke, DJ Webb, N Dhaun, JW Dear, JJ Mullins, MA Bailey
Hypertension 2020
Contemporary patterns in kidney graft survival from donors after circulatory death in the United States
CR Butler, JD Perkins, CK Johnson, CD Blosser, ID Castro, N Leca, L Sibulesky, FJ Dor
PloS one 2020
Experimental rat model for acute tubular injury induced by high water hardness and high water fluoride: efficacy of primary preventive intervention by distilled water administration
T Perera, S Ranasinghe, N Alles, R Waduge
BMC Nephrology 2020
Role of MIF Cytokine/CD74 Receptor Pathway in Protecting Against Injury and Promoting Repair
L Farr, S Ghosh, S Moonah
Frontiers in immunology 2020
Epithelial and Endothelial Adhesion of Immune Cells Is Enhanced by Cardiotonic Steroid Signaling Through Na + /K + ‐ATPase‐α‐1
FK Khalaf, I Tassavvor, A Mohamed, Y Chen, D Malhotra, Z Xie, J Tian, ST Haller, K Westfall, WH Tang, DJ Kennedy
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease 2020
Defective Mitochondrial Fatty Acid Oxidation and Lipotoxicity in Kidney Diseases
HS Jang, MR Noh, J Kim, BJ Padanilam
Frontiers in Medicine 2020
Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury
Beach TE, Prag HA, Pala L, Logan A, Huang MM, Gruszczyk AV, Martin JL, Mahbubani K, Hamed MO, Hosgood SA, Nicholson ML, James AM, Hartley RC, Murphy MP, Saeb-Parsy K
Redox Biology 2020
Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involvement of ERK/mTOR Pathways
Tian R, Wang P, Huang L, Li C, Lu Z, Lu Z, Wu A, Bao K, Mao W, Huang Q, Xu P
Frontiers in pharmacology 2020
Cardiac surgery-associated acute kidney injury: pathophysiology and diagnostic modalities and management
Leballo G, Motshabi P
CardioVascular Journal of Africa 2020
The Neutrophil Percentage-to-Albumin Ratio Is Associated with All-Cause Mortality in Critically Ill Patients with Acute Kidney Injury
Wang B, Li D, Cheng B, Ying B, Gong Y
BioMed Research International 2020
Non-diabetic glycosuria as a diagnostic clue for acute tubulointerstitial nephritis in patients with azotemia
Lee T, Yang WS
Renal Failure 2020
Comparative study on the curative effect of laparoscopic nephron sparing surgery and renal functions under selective segmental renal artery clamping and main renal artery clamping
Liu YH, Dai HT, Liu CM, Wang ZY, Zheng J
Pakistan Journal of Medical Sciences 2020
The Mechanisms of the Herbal Components of CRSAS on HK-2 Cells in a Hypoxia/Reoxygenation Model Based on Network Pharmacology
Ye N, Xie D, Yang B, Li M
Evidence-based complementary and alternative medicine : eCAM 2020
Is the kidney a target of SARS-CoV-2?
Martinez-Rojas MA, Vega-Vega O, Bobadilla NA
AJP Renal Physiology 2020
Effects of prostaglandin E combined with continuous renal replacement therapy on septic acute kidney injury
Lei L, Wang MJ, Zhang S, Hu DJ
World journal of clinical cases 2020
The effect of adipose-derived mesenchymal stem cells on renal function and histopathology in a rat model of ischemia-reperfusion induced acute kidney injury
Changizi-Ashtiyani S, Hafazeh L, Ghasemi F, Najafi H, Babaei S, JalallyMashayekhi F, Hoseini SJ, Bastani B
Iranian Journal of Basic Medical Sciences 2020
Reoxygenation induces reactive oxygen species production and ferroptosis in renal tubular epithelial cells by activating aryl hydrocarbon receptor
Eleftheriadis T, Pissas G, Filippidis G, Liakopoulos V, Stefanidis I
Molecular medicine reports 2020
Oxidative stress and decreased tissue HSP70 are involved in the genesis of sepsis: HSP70 as a therapeutic target
Sulzbacher MM, Ludwig MS, Heck TG
Revista Brasileira de Terapia Intensiva 2020
Mistimed H2S upregulation, Nrf2 activation and antioxidant proteins levels in renal tubular epithelial cells subjected to anoxia and reoxygenation
Eleftheriadis T, Pissas G, Nikolaou E, Filippidis G, Liakopoulos V, Stefanidis I
Biomedical Reports 2020
The Effect of Shen Qi Wan Medicated Serum on NRK-52E Cells Proliferation and Migration by Targeting Aquaporin 1 (AQP1)
He Y, Bao YT, Chen HS, Chen YT, Zhou XJ, Yang YX, Li CY
Medical science monitor : international medical journal of experimental and clinical research 2020
The Effects of Ascorbic Acid and U-74389G on Renal Ischemia-Reperfusion Injury in a Rat Model
ZOGRAFOS CG, CHRYSIKOS D, PITTARAS T, KARAMPELIAS V, CHAIRAKAKIS A, GALANOS A, SFINIADAKIS I, FELEKOURAS E, ZOGRAFOS GC, SIDERIS M, PAPADOPOULOU K, PAPALOIS AE
In vivo (Athens, Greece) 2020
Fibroblast Growth Factor 2 Attenuates Renal Ischemia-Reperfusion Injury via Inhibition of Endoplasmic Reticulum Stress
Tan X, Tao Q, Li G, Xiang L, Zheng X, Zhang T, Wu C, Li D
Frontiers in Cell and Developmental Biology 2020
Epigenetics in kidney diseases
Ding H, Zhang L, Yang Q, Zhang X, Li X
Advances in Clinical Chemistry 2020
Xanthine oxidase inhibitor ameliorates post-ischemic renal injury in mice by promoting re-synthesis of adenine nucleotides
Kentaro Fujii, Akiko Kubo, Kazutoshi Miyashita, Masaaki Sato, Aika Hagiwara, Hiroyuki Inoue, Masaki Ryuzaki, Masanori Tamaki, Takako Hishiki, Noriyo Hayakawa, Yasuaki Kabe, Hiroshi Itoh, Makoto Suematsu
JCI Insight 2019
Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses
Seiji Kishi, Craig R. Brooks, Kensei Taguchi, Takaharu Ichimura, Yutaro Mori, Akinwande Akinfolarin, Navin Gupta, Pierre Galichon, Bertha C Elias, Tomohisa Suzuki, Qian Wang, Leslie Gewin, Ryuji Morizane, Joseph V. Bonventre
Journal of Clinical Investigation 2019
Periostin Promotes Cell Proliferation and Macrophage Polarization to Drive Repair after AKI
R Kormann, P Kavvadas, S Placier, S Vandermeersch, A Dorison, JC Dussaule, CE Chadjichristos, N Prakoura, C Chatziantoniou
Journal of the American Society of Nephrology : JASN 2019
Bif-1 Interacts with Prohibitin-2 to Regulate Mitochondrial Inner Membrane during Cell Stress and Apoptosis
SG Cho, X Xiao, S Wang, H Gao, R Rafikov, S Black, S Huang, HF Ding, Y Yoon, RA Kirken, XM Yin, HG Wang, Z Dong
Journal of the American Society of Nephrology : JASN 2019
Perivascular CD73 + cells attenuate inflammation and interstitial fibrosis in the kidney microenvironment
HM Perry, N Görldt, SJ Sung, L Huang, KP Rudnicka, IM Encarnacion, A Bajwa, S Tanaka, N Poudel, J Yao, DL Rosin, J Schrader, MD Okusa
American journal of physiology. Renal physiology 2019
Neuroimmunomodulation of tissue injury and disease: an expanding view of the inflammatory reflex pathway
S Tanaka, B Hammond, DL Rosin, MD Okusa
Bioelectronic medicine 2019
Gcm1 is involved in cell proliferation and fibrosis during kidney regeneration after ischemia–reperfusion injury
S Kamejima, N Tatsumi, A Anraku, H Suzuki, I Ohkido, T Yokoo, M Okabe
Scientific Reports 2019
Complement-mediated Damage to the Glycocalyx Plays a Role in Renal Ischemia-reperfusion Injury in Mice:
AK Bongoni, B Lu, JL McRae, EJ Salvaris, EJ Toonen, I Vikstrom, AB Morelli, MJ Pearse, PJ Cowan
Transplantation Direct 2019
FTY720 Effects on Inflammation and Liver Damage in a Rat Model of Renal Ischemia-Reperfusion Injury
AD Foster, D Vicente, N Clark, C Leonhardt, EA Elster, TA Davis, MJ Bradley
Mediators of Inflammation 2019
Anti-donor MHC Class II Alloantibody Induces Glomerular Injury in Mouse Renal Allografts Subjected to Prolonged Cold Ischemia
V Gorbacheva, R Fan, A Beavers, RL Fairchild, WM Baldwin, A Valujskikh
Journal of the American Society of Nephrology : JASN 2019
Biomarkers of Acute and Chronic Kidney Disease
WR Zhang, CR Parikh
Annual Review of Physiology 2019
Why Have Detection, Understanding and Management of Kidney Hypoxic Injury Lagged Behind those for the Heart?
Z Abassi, S Rosen, S Lamothe, SN Heyman
Journal of Clinical Medicine 2019
Mechanisms and therapeutic targets of ischemic acute kidney injury
SJ Han, HT Lee
Kidney Research and Clinical Practice 2019
Found in Translation: Reasons for Optimism in the Pursuit to Prevent Chronic Kidney Disease After Acute Kidney Injury
SA Silver, C Gerarduzzi
Canadian Journal of Kidney Health and Disease 2019
Dendritic Cells as Sensors, Mediators, and Regulators of Ischemic Injury
H Dai, AW Thomson, NM Rogers
Frontiers in immunology 2019
LPS-Binding Protein Modulates Acute Renal Fibrosis by Inducing Pericyte-to-Myofibroblast Trans-Differentiation through TLR-4 Signaling
G Castellano, A Stasi, R Franzin, F Sallustio, C Divella, A Spinelli, GS Netti, E Fiaccadori, V Cantaluppi, A Crovace, F Staffieri, L Lacitignola, G Grandaliano, S Simone, GB Pertosa, L Gesualdo
International journal of molecular sciences 2019
Genetic communication by extracellular vesicles is an important mechanism underlying stem cell-based therapy-mediated protection against acute kidney injury
L Zhao, C Hu, P Zhang, H Jiang, J Chen
Stem Cell Research & Therapy 2019
Cellular Senescence and the Kidney: Potential Therapeutic Targets and Tools
SN Knoppert, FA Valentijn, TQ Nguyen, R Goldschmeding, LL Falke
Frontiers in pharmacology 2019
Chlorogenic Acid Attenuates Kidney Ischemic/Reperfusion Injury via Reducing Inflammation, Tubular Injury, and Myofibroblast Formation
N Arfian, DA Wahyudi, IB Zulfatina, AN Citta, N Anggorowati, A Multazam, MM Romi, DC Sari
BioMed Research International 2019
Integrin-Linked Kinase Deficiency in Collecting Duct Principal Cell Promotes Necroptosis of Principal Cell and Contributes to Kidney Inflammation and Fibrosis
M Huang, S Zhu, H Huang, J He, K Tsuji, WW Jin, D Xie, O Ham, DE Capen, W Lu, TG Păunescu, B Yang, HA Lu
Journal of the American Society of Nephrology : JASN 2019
Translational Assessment of Drug‐Induced Proximal Tubule Injury Using a Kidney Microphysiological System
C Maass, NB Sorensen, J Himmelfarb, EJ Kelly, CL Stokes, M Cirit
CPT Pharmacometrics Syst. Pharmacol. 2019
Cyclin G1 and TASCC regulate kidney epithelial cell G 2 -M arrest and fibrotic maladaptive repair
G Canaud, CR Brooks, S Kishi, K Taguchi, K Nishimura, S Magassa, A Scott, LL Hsiao, T Ichimura, F Terzi, L Yang, JV Bonventre
Science Translational Medicine 2019
Renal ischemia-reperfusion injury impairs renal calcium, magnesium, and phosphate handling in mice
M Meurer, K Höcherl
Pflügers Archiv - European Journal of Physiology 2019
The role of PAK1 in the sensitivity of kidney epithelial cells to ischemia-like conditions
ER Zynda, MH Maloy, ES Kandel
Cell cycle (Georgetown, Tex.) 2019
Kynurenine 3-monooxygenase is a critical regulator of renal ischemia–reperfusion injury
X Zheng, A Zhang, M Binnie, K McGuire, SP Webster, J Hughes, SE Howie, DJ Mole
Experimental & molecular medicine 2019
EZH2 plays a crucial role in ischemia/reperfusion-induced acute kidney injury by regulating p38 signaling
H Liang, Q Huang, M Liao, F Xu, T Zhang, J He, L Zhang, H Liu
Inflammation Research 2019
Matrix metalloproteinase-7 protects against acute kidney injury by priming renal tubules for survival and regeneration
H Fu, D Zhou, H Zhu, J Liao, L Lin, X Hong, FF Hou, Y Liu
Kidney International 2019
Fully automated analysis of OCT imaging of human kidneys for prediction of post-transplant function
B Konkel, C Lavin, TT Wu, E Anderson, A Iwamoto, H Rashid, B Gaitian, J Boone, M Cooper, P Abrams, A Gilbert, Q Tang, M Levi, JG Fujimoto, P Andrews, Y Chen
Biomedical Optics Express 2019
An Increasing Neutrophil-to-Lymphocyte Ratio Trajectory Predicts Organ Failure in Critically-Ill Male Trauma Patients. An Exploratory Study
D Younan, J Richman, A Zaky, JF Pittet
Healthcare 2019
Novel insights into MSC-EVs therapy for immune diseases
P Lai, J Weng, L Guo, X Chen, X Du
Biomarker Research 2019
Neutrophil Gelatinase-associated Lipocalin Significantly Correlates with Ischemic Damage in Patients Undergoing Laparoscopic Partial Nephrectomy
MS Karadeniz, IA Enişte, HŞ Çiftçi, S Usta, T Tefik, Ö Şanlı, K Pembeci, KM Tuğrul
BALK MED J 2019
Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury
GJ Cameron, KM Cautivo, S Loering, SH Jiang, AV Deshpande, PS Foster, AN McKenzie, AB Molofsky, PM Hansbro, MR Starkey
Frontiers in immunology 2019
Pharmacological inhibition of TRPV4 channels protects against ischemia–reperfusion-induced renal insufficiency in neonatal pigs
H Soni, D Peixoto-Neves, MA Olushoga, A Adebiyi
Clinical Science 2019
Ethyl Pyruvate Directly Attenuates Active Secretion of HMGB1 in Proximal Tubular Cells via Induction of Heme Oxygenase-1
MS Seo, HJ Kim, H Kim, SW Park
Journal of Clinical Medicine 2019
Pharmacological Protection of Kidney Grafts from Cold Perfusion-Induced Injury
A Krzywonos-Zawadzka, A Franczak, MA Moser, A Olejnik, G Sawicki, I Bil-Lula
BioMed Research International 2019
Urine podoplanin heralds the onset of ischemia-reperfusion injury of the kidney
V Kasinath, OA Yilmam, M Uehara, M Yonar, L Jiang, X Li, W Qiu, S Eskandari, T Ichimura, R Abdi
American journal of physiology. Renal physiology 2019
The predictive value of the prognostic nutritional index for postoperative acute kidney injury in patients undergoing on-pump coronary bypass surgery
A Dolapoglu, E Avci, T Kiris, O Bugra
Journal of Cardiothoracic Surgery 2019
Attenuation of Acute Renal Injury After the Post-resuscitation Administration of Doxycycline in Surviving Newborn Piglets With Severe Hypoxia-Reoxygenation
TF Lee, M Lu, MP Pasquin, GM Schmölzer, PY Cheung
Frontiers in Pediatrics 2019
Fibroblast mTOR/PPARγ/HGF axis protects against tubular cell death and acute kidney injury
Y Gui, Q Lu, M Gu, M Wang, Y Liang, X Zhu, X Xue, X Sun, W He, J Yang, AZ Zhao, B Xiao, C Dai
Cell Death and Differentiation 2019
Factors that May Protect the Native Hibernator Syrian Hamster Renal Tubular Epithelial Cells from Ferroptosis Due to Warm Anoxia-Reoxygenation
T Eleftheriadis, G Pissas, V Liakopoulos, I Stefanidis
Biology : open access journal 2019
Lack of Cathepsin D in the Renal Proximal Tubular Cells Resulted in Increased Sensitivity against Renal Ischemia/Reperfusion Injury
C Suzuki, I Tanida, M Ohmuraya, JO Trejo, S Kakuta, T Sunabori, Y Uchiyama
International journal of molecular sciences 2019
Protective effects of celecoxib on ischemia reperfusion-induced acute kidney injury: comparing between male and female rats
Farzaneh Kianian, Behjat Seifi, Mehri Kadkhodaee, Abdullah Sajedizadeh, Parisa Ahghari
Iranian Journal of Basic Medical Sciences 2019
Pirfenidone prevents acute kidney injury in the rat
I Lima-Posada, F Fontana, R Pérez-Villalva, N Berman-Parks, NA Bobadilla
BMC Nephrology 2019
NADPH oxidase 4 mediates TGF-β1/Smad signaling pathway induced acute kidney injury in hypoxia
S Cho, SL Yu, J Kang, BY Jeong, HY Lee, CG Park, YB Yu, DC Jin, WM Hwang, SR Yun, HS Song, MH Park, SH Yoon, HH Schmidt
PloS one 2019
Gene deletion of the Na + -glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion
J Nespoux, R Patel, KL Hudkins, W Huang, B Freeman, YC Kim, H Koepsell, CE Alpers, V Vallon
American journal of physiology. Renal physiology 2019
Blocking interleukin-6 trans-signaling protects against renal fibrosis by suppressing STAT3 activation
W Chen, H Yuan, W Cao, T Wang, W Chen, H Yu, Y Fu, B Jiang, H Zhou, H Guo, X Zhao
Theranostics 2019
Determinants of preferential renal accumulation of synthetic polymers in acute kidney injury
Y Chen, W Tang, F Yu, Y Xie, L Jaramillo, HS Jang, J Li, BJ Padanilam, D Oupický
International Journal of Pharmaceutics 2019
The Anti-Inflammatory, Anti-Oxidative, and Anti-Apoptotic Benefits of Stem Cells in Acute Ischemic Kidney Injury
KH Lee, WC Tseng, CY Yang, DC Tarng
International journal of molecular sciences 2019
Early activation of fibroblasts is required for kidney repair and regeneration after injury
D Zhou, H Fu, S Liu, L Zhang, L Xiao, SI Bastacky, Y Liu
The FASEB Journal 2019
New mouse model of chronic kidney disease transitioned from ischemic acute kidney injury
J Wei, J Zhang, L Wang, S Jiang, L Fu, J Buggs, R Liu
American journal of physiology. Renal physiology 2019
Functional regulation of von Willebrand factor ameliorates acute ischemia-reperfusion kidney injury in mice
S Ono, H Matsui, M Noda, S Kasuda, N Yada, K Yoshimoto, M Akiyama, T Miyata, M Sugimoto, K Nishio
Scientific Reports 2019
Zinc Supplementation and Ischemia Pre-conditioning in Renal Ischemia/Reperfusion Injury
B Mazaheri, F Emami, A Talebi, M Nematbakhsh
The Malaysian Journal of Medical Sciences : MJMS 2019
A mouse model of renal ischemia-reperfusion injury solely induced by cold ischemia
J Wei, Y Wang, J Zhang, L Wang, L Fu, BJ Cha, J Buggs, R Liu
American journal of physiology. Renal physiology 2019
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway
S Tang, J Wang, J Liu, Y Huang, Y Zhou, S Yang, W Zhang, M Yang, H Zhang
Renal Failure 2019
The Effect of Overexpression of the Enhancer of Zeste Homolog 1 (EZH1) Gene on Aristolochic Acid-Induced Injury in HK-2 Human Kidney Proximal Tubule Cells In Vitro
L Wang, N Liu, X Xue, S Zhou
Medical science monitor : international medical journal of experimental and clinical research 2019
IgA nephropathy is associated with elevated urinary mitochondrial DNA copy numbers
BC Yu, NJ Cho, S Park, H Kim, SJ Choi, JK Kim, SD Hwang, HW Gil, EY Lee, JS Jeon, H Noh, DC Han, YH Kim, SY Jin, MY Park, SH Kwon
Scientific Reports 2019
Cell-free hemoglobin augments acute kidney injury during experimental sepsis
CM Shaver, MG Paul, ND Putz, SR Landstreet, JL Kuck, L Scarfe, N Skrypnyk, H Yang, FE Harrison, MP de Caestecker, JA Bastarache, LB Ware
American journal of physiology. Renal physiology 2019
Current understanding of the administration of mesenchymal stem cells in acute kidney injury to chronic kidney disease transition: a review with a focus on preclinical models
L Zhao, F Han, J Wang, J Chen
Stem Cell Research & Therapy 2019
Renal abnormalities among children with sickle cell conditions in highly resource-limited setting in Ghana
EO Anto, C Obirikorang, E Acheampong, E Adua, S Donkor, BO Afranie, M Ofori, EA Asiamah, EA Adu, JA Hirst
PloS one 2019
Identification and classification of epithelial cells in nephron segments by actin cytoskeleton patterns
GK Kumaran, I Hanukoglu
The FEBS journal 2019
p53-cyclophilin D mediates renal tubular cell apoptosis in ischemia-reperfusion-induced acute kidney injury
H Yang, R Li, L Zhang, S Zhang, W Dong, Y Chen, W Wang, C Li, Z Ye, X Zhao, Z Li, Y Wu, M Zhang, S Liu, Z Dong, X Liang
American journal of physiology. Renal physiology 2019
Labile Heme Aggravates Renal Inflammation and Complement Activation After Ischemia Reperfusion Injury
L Wang, V Vijayan, MS Jang, A Thorenz, R Greite, S Rong, R Chen, N Shushakova, I Tudorache, K Derlin, P Pradhan, K Madyaningrana, N Madrahimov, JH Bräsen, R Lichtinghagen, C van Kooten, M Huber-Lang, H Haller, S Immenschuh, F Gueler
Frontiers in immunology 2019
Minor Glomerular Abnormalities are Associated with Deterioration of Long-Term Kidney Function and Mitochondrial Injury
BC Yu, NJ Cho, S Park, H Kim, HW Gil, EY Lee, SH Kwon, JS Jeon, H Noh, DC Han, A Moon, SJ Park, JK Kim, SD Hwang, SJ Choi, MY Park
Journal of Clinical Medicine 2019
Acute Kidney Injury
R Weiss, M Meersch, HJ Pavenstädt, A Zarbock
Deutsches Ärzteblatt international 2019
Nobiletin Protects from Renal Ischemia-Reperfusion Injury in Rats by Suppressing Inflammatory Cytokines and Regulating iNOS-eNOS Expressions
M Güvenç, M Cellat, A Uyar, H Özkan, İ Gokcek, CT İsler, A Yakan
Inflammation 2019
The Effects of Meldonium on the Renal Acute Ischemia/Reperfusion Injury in Rats
Đurašević, Stojković, Bogdanović, Pavlović, BM, Grigorov, Bogojević, Jasnić, Tosti, Đurović, Đorđević, Todorović
International journal of molecular sciences 2019
Pyrogallol-Phloroglucinol-6,6-Bieckol from Ecklonia cava Attenuates Tubular Epithelial Cell (TCMK-1) Death in Hypoxia/Reoxygenation Injury
M Son, S Oh, CH Choi, KY Park, KH Son, K Byun
Marine drugs 2019
Effects of early high-dose erythropoietin on acute kidney injury following cardiac arrest: exploratory post hoc analyses from an open-label randomized trial
L Guillemet, M Jamme, W Bougouin, G Geri, N Deye, B Vivien, O Varenne, F Pène, JP Mira, F Barat, JM Treluyer, O Hermine, P Carli, J Coste, A Cariou, A Cariou, N Deye, B Vivien, O Richard, N Pichon, A Bourg, L Huet, C Buleon, J Frey, P Asfar, S Legriel, S Narcisse, A Mathonnet, A Cravoisy, PF Dequin, E Wiel, K Razazi, C Daubin, A Kimmoun, L Lamhaut, JS Marx, DP de la Garanderie, P Ecollan, A Combes, C Spaulding, F Barat, MB Boutieb, J Coste, JD Chiche, F Pène, JP Mira, JM Treluyer, O Hermine, P Carli
Clinical Kidney Journal 2019
Kidney Injury Biomarkers in an Academic Hospital Setting: Where Are We Now?
van Duijl TT, Ruhaak LR, de Fijter JW, Cobbaert CM
The Clinical Biochemist Reviews 2019
Ethanol Extract of Centella asiatica (Gotu Kola) Attenuates Tubular Injury Through Inhibition of Inflammatory Cytokines and Enhancement of Anti-Fibrotic Factor in Mice with 5/6 Subtotal Nephrectomy
Arfian N, Setyaningsih WA, Anggorowati N, Romi MM, Sari DC
The Malaysian Journal of Medical Sciences : MJMS 2019
The H2S–Nrf2–Antioxidant Proteins Axis Protects Renal Tubular Epithelial Cells of the Native Hibernator Syrian Hamster from Reoxygenation-Induced Cell Death
Eleftheriadis T, Pissas G, Nikolaou E, Liakopoulos V, Stefanidis I
Biology 2019
Crosstalk Between Connexin32 and Mitochondrial Apoptotic Signaling Pathway Plays a Pivotal Role in Renal Ischemia Reperfusion-Induced Acute Kidney Injury
Chen C, Yao W, Wu S, Zhou S, Ge M, Gu Y, Li X, Chen G, Bellanti JA, Zheng SG, Yuan D, Hei Z
Antioxidants & Redox Signaling 2019
Temporal changes in urinary excretion of liver-type fatty acid binding protein (L-FABP) in acute kidney injury model of domestic cats: a preliminary study
KATAYAMA M, MIYAZAKI T, OHATA K, OIKAWA T, KAMIIE J, SUGAYA T, MIYAZAKI M
Journal of Veterinary Medical Science 2019
Acute kidney injury and adverse outcomes of critical illness: correlation or causation?
Girling BJ, Channon SW, Haines RW, Prowle JR
Clinical Kidney Journal 2019
Acute Kidney Injury and Fluid Overload in Pediatric Cardiac Surgery
Carlisle MA, Soranno DE, Basu RK, Gist KM
Current Treatment Options in Pediatrics 2019
Evaluation with endothelial nitric oxide synthase (eNOS) immunoreactivity of the protective role of astaxanthin on hepatorenal injury of remote organs caused by ischaemia reperfusion of the lower extremities
Uyar A, Yaman T
2019
Additional effects of erythropoietin pretreatment, ischemic preconditioning, and N-acetylcysteine posttreatment in rat kidney reperfusion injury
ELSHIEKH M, KADKHODAEE M, SEIFI B, RANJBARAN M
2019
Acute kidney injury overview: From basic findings to new prevention and therapy strategies
Gonsalez SR, Cortês AL, da Silva RC, Lowe J, Prieto MC, Lara LD
Pharmacology & Therapeutics 2019
A protective role for mircoRNA-688 in acute kidney injury
Nicholas Chun, Steven Coca, John Cijiang He
Journal of Clinical Investigation 2018
Repetitive ischemic injuries to the kidneys result in lymph node fibrosis and impaired healing
Omar Maarouf, Mayuko Uehara, Vivek Kasinath, Zhabiz Solhjou, Naima Banouni, Baharak Bahmani, Liwei Jiang, Osman A Yilmam, Indira Guleria, Scott Lovitch, Jane Grogan, Paolo Fiorina, Peter Sage, Jonathan Bromberg, Martina McGrath, Reza Abdi
JCI Insight 2018
microRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury
Qingqing Wei, Haipeng Sun, Shuwei Song, Yong Liu, Pengyuan Liu, Man J. Livingston, Jianwen Wang, Mingyu Liang, Qing-Sheng Mi, Yuqing Huo, Stanley Nahman, changlin mei, Zheng Dong
Journal of Clinical Investigation 2018
Potentiating Tissue-Resident Type 2 Innate Lymphoid Cells by IL-33 to Prevent Renal Ischemia-Reperfusion Injury
Q Cao, Y Wang, Z Niu, C Wang, R Wang, Z Zhang, T Chen, XM Wang, Q Li, VW Lee, Q Huang, J Tan, M Guo, YM Wang, G Zheng, D Yu, SI Alexander, H Wang, DC Harris
Journal of the American Society of Nephrology : JASN 2018
Blocking Macrophage Migration Inhibitory Factor Protects Against Cisplatin-Induced Acute Kidney Injury in Mice
J Li, Y Tang, PM Tang, J Lv, X Huang, C Carlsson-Skwirut, LD Costa, A Aspesi, S Fröhlich, P Szczęśniak, P Lacher, J Klug, A Meinhardt, G Fingerle-Rowson, R Gong, Z Zheng, A Xu, H Lan
Molecular Therapy 2018
PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury
C Tang, H Han, M Yan, S Zhu, J Liu, Z Liu, L He, J Tan, Y Liu, H Liu, L Sun, S Duan, Y Peng, F Liu, XM Yin, Z Zhang, Z Dong
Autophagy 2018
Sirtuins in Renal Health and Disease
M Morigi, L Perico, A Benigni
Journal of the American Society of Nephrology : JASN 2018
Graft Pre-conditioning by Peri-Operative Perfusion of Kidney Allografts With Rabbit Anti-human T-lymphocyte Globulin Results in Improved Kidney Graft Function in the Early Post-transplantation Period—a Prospective, Randomized Placebo-Controlled Trial
PV Ritschl, J Günther, L Hofhansel, AA Kühl, A Sattler, S Ernst, F Friedersdorff, S Ebner, S Weiss, C Bösmüller, A Weissenbacher, R Oberhuber, B Cardini, R Öllinger, S Schneeberger, M Biebl, C Denecke, C Margreiter, T Resch, F Aigner, M Maglione, J Pratschke, K Kotsch
Frontiers in immunology 2018
Ischaemia reperfusion injury: mechanisms of progression to chronic graft dysfunction
GR Situmorang, NS Sheerin
Pediatric Nephrology 2018
Neuroimmune Communication in Health and Disease
C Reardon, K Murray, AE Lomax
Physiological reviews 2018
Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling
C Hu, L Li, P Ding, L Li, X Ge, L Zheng, X Wang, J Wang, W Zhang, N Wang, H Gu, F Zhong, M Xu, R Rong, T Zhu, W Hu
Journal of immunology (Baltimore, Md. : 1950) 2018
Characterization of kidney CD45intCD11bintF4/80+MHCII+CX3CR1+Ly6C- “intermediate mononuclear phagocytic cells”
SA Lee, S Noel, M Sadasivam, ME Allaf, PM Pierorazio, AR Hamad, H Rabb, D Long
PloS one 2018
Acute Kidney Injury and Progression of Diabetic Kidney Disease
SM Yu, JV Bonventre
Advances in Chronic Kidney Disease 2018
Endothelial prostacyclin protects the kidney from ischemia-reperfusion injury
Y Cao, Y Guan, YY Xu, CM Hao
Pflügers Archiv - European Journal of Physiology 2018
Paradigms of acute kidney injury in the intensive care setting
JA Kellum, JR Prowle
Nature Reviews Nephrology 2018
Extract of Rhus�verniciflua stokes protects against renal ischemia-reperfusion injury by enhancing Nrf2-mediated induction of antioxidant enzymes
D Choi, J Jeong, KS Yu, NS Lee, YG Jeong, D Kim, C Na, D Na, W Hwang, SY Han
Experimental and therapeutic medicine 2018
Cannabinoid-1 receptor regulates mitochondrial dynamics and function in renal proximal tubular cells
A Drori, A Permyakova, R Hadar, S Udi, A Nemirovski, J Tam
Diabetes, obesity & metabolism 2018
Tubular epithelial C1orf54 mediates protection and recovery from acute kidney injury
H Xie, Y Wang, H Zhang, Q Fan, D Dai, L Zhuang, R Tao, Q Chen, W Shen, L Lu, X Ding, R Zhang, X Yan
Journal of Cellular and Molecular Medicine 2018
Acute Kidney Injury as a Condition of Renal Senescence
L Andrade, CE Rodrigues, SA Gomes, IL Noronha
Cell Transplantation 2018
Resveratrol ameliorates sepsis‑induced acute kidney injury in a pediatric rat model via Nrf2 signaling pathway
Y Wang, F Feng, M Liu, J Xue, H Huang
Experimental and therapeutic medicine 2018
Tim-3 exacerbates kidney ischaemia/reperfusion injury through the TLR-4/NF-κB signalling pathway and an NLR-C4 inflammasome activation: The role of Tim-3 in kidney IRI
Y Guo, J Zhang, X Lai, M Chen, Y Guo
Clinical & Experimental Immunology 2018
Effects of erythropoietin receptor activity on angiogenesis, tubular injury, and fibrosis in acute kidney injury: a “U-shaped” relationship
M Shi, B Flores, P Li, N Gillings, KL McMillan, J Ye, LJ Huang, SS Sidhu, YP Zhong, MT Grompe, PR Streeter, OW Moe, MC Hu
American journal of physiology. Renal physiology 2018
A zebrafish model of infection-associated acute kidney injury
X Wen, L Cui, S Morrisroe, D Maberry, D Emlet, S Watkins, NA Hukriede, JA Kellum
American journal of physiology. Renal physiology 2018
Epithelial Cell Cycle Behaviour in the Injured Kidney
L Moonen, P DHaese, B Vervaet
International journal of molecular sciences 2018
Renal vascular pericytes: long overlooked and poorly understood, but clearly important, and what about those regulatory pathways?
TL Pannabecker
American journal of physiology. Renal physiology 2018
RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism
W Liu, B Chen, Y Wang, C Meng, H Huang, XR Huang, J Qin, SR Mulay, HJ Anders, A Qiu, B Yang, GJ Freeman, HJ Lu, HY Lin, ZH Zheng, HY Lan, Y Huang, Y Xia
Proceedings of the National Academy of Sciences 2018
miR-17-92 ameliorates renal ischemia reperfusion injury
T Song, M Chen, Z Rao, Y Qiu, J Liu, Y Jiang, Z Huang, X Wang, T Lin
The Kaohsiung Journal of Medical Sciences 2018
Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation
TT Tang, LL Lv, MM Pan, Y Wen, B Wang, ZL Li, M Wu, FM Wang, SD Crowley, BC Liu
Cell Death and Disease 2018
Oxidized phosphatidylcholines are produced in renal ischemia reperfusion injury
Z Solati, AL Edel, Y Shang, K O, A Ravandi, T Shimosawa
PloS one 2018
Adaptive responses of rat descending vasa recta to ischemia
Z Zhang, K Payne, TL Pallone
American journal of physiology. Renal physiology 2018
Bilirubin, a new therapeutic for kidney transplant?
VL Sundararaghavan, S Binepal, DE Stec, P Sindhwani, TD Hinds
Transplantation reviews (Orlando, Fla.) 2018
Aristolochic acid I determine the phenotype and activation of macrophages in acute and chronic kidney disease
M Honarpisheh, O Foresto-Neto, S Steiger, F Kraft, P Koehler, E von Rauchhaupt, J Potempa, K Adamowicz, J Koziel, M Lech
Scientific Reports 2018
N- acetyl-cysteine increases cellular dysfunction in progressive chronic kidney damage after acute kidney injury by dampening endogenous antioxidant responses
DM Small, WY Sanchez, SF Roy, C Morais, HL Brooks, JS Coombes, DW Johnson, GC Gobe
American journal of physiology. Renal physiology 2018
CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury
TA Yakulov, AP Todkar, K Slanchev, J Wiegel, A Bona, M Groß, A Scholz, I Hess, A Wurditsch, F Grahammer, TB Huber, V Lecaudey, T Bork, J Hochrein, M Boerries, J Leenders, P de Tullio, F Jouret, A Kramer-Zucker, G Walz
Nature Communications 2018
miR-214 ameliorates acute kidney injury via targeting DKK3 and activating of Wnt/β-catenin signaling pathway
X Zhu, W Li, H Li
Biological research 2018
Comprehensive renoprotective effects of ipragliflozin on early diabetic nephropathy in mice
M Kamezaki, T Kusaba, K Komaki, Y Fushimura, N Watanabe, K Ikeda, T Kitani, N Yamashita, M Uehara, Y Kirita, Y Shiotsu, R Sakai, T Fukuda, M Yamazaki, M Fukui, S Matoba, K Tamagaki
Scientific Reports 2018
Acute kidney injury in children with chronic liver disease
A Deep, R Saxena, B Jose
Pediatric Nephrology 2018
Distinct inflammatory profile underlies pathological increases in creatinine levels associated with Plasmodium vivax malaria clinical severity
LA Cruz, M Barral-Netto, BB Andrade, AA Escalante
PLoS neglected tropical diseases 2018
Single Graft Utilization From Donors With Severe Acute Kidney Injury After Circulatory Death:
Y Tomita, K Iwadoh, Y Ogawa, K Miki, K Kai, A Sannomiya, T Murakami, I Koyama, K Kitajima, I Nakajima, S Fuchinoue
Transplantation Direct 2018
AIM associated with the IgM pentamer: attackers on stand-by at aircraft carrier
T Miyazaki, T Yamazaki, R Sugisawa, ME Gershwin, S Arai
Cellular and Molecular Immunology 2018
Carbon monoxide protects the kidney through the central circadian clock and CD39
M Correa-Costa, D Gallo, E Csizmadia, E Gomperts, JL Lieberum, CJ Hauser, X Ji, B Wang, NO Câmara, SC Robson, LE Otterbein
Proceedings of the National Academy of Sciences 2018
The role of macrophages during acute kidney injury: destruction and repair
HI Han, LB Skvarca, EB Espiritu, AJ Davidson, NA Hukriede
Pediatric Nephrology 2018
Stem/Stromal Cells for Treatment of Kidney Injuries With Focus on Preclinical Models
AT Crigna, C Daniele, C Gamez, SM Balbuena, DO Pastene, D Nardozi, C Brenna, B Yard, N Gretz, K Bieback
Frontiers in Medicine 2018
The Protective Effect of A Short Peptide Derived From Cold-Inducible RNA-Binding Protein in Renal Ischemia–Reperfusion Injury:
J McGinn, F Zhang, M Aziz, WL Yang, J Nicastro, GF Coppa, P Wang
Shock 2018
Kidney atrophy vs hypertrophy in diabetes: which cells are involved?
SL Habib
Cell cycle (Georgetown, Tex.) 2018
Pharmacological inhibition of fatty acid-binding protein 4 (FABP4) protects against renal ischemia-reperfusion injury
M Shi, R Huang, F Guo, L Li, Y Feng, Z Wei, L Zhou, L Ma, P Fu
RSC Advances 2018
Urinary Mitochondrial DNA Identifies Renal Dysfunction and Mitochondrial Damage in Sepsis-Induced Acute Kidney Injury
Q Hu, J Ren, H Ren, J Wu, X Wu, S Liu, G Wang, G Gu, K Guo, J Li
Oxidative medicine and cellular longevity 2018
Enhanced protection of the renal vascular endothelium improves early outcome in kidney transplantation: Preclinical investigations in pig and mouse
S Nordling, J Brännström, F Carlsson, B Lu, E Salvaris, A Wanders, J Buijs, S Estrada, V Tolmachev, PJ Cowan, T Lorant, PU Magnusson
Scientific Reports 2018
Syndecan-1 Shedding Inhibition to Protect Against Ischemic Acute Kidney Injury Through HGF Target Signaling Pathway:
Z Lu, N Song, B Shen, XL Xu, Y Fang, Y Shi, Y Ning, J Hu, Y Dai, X Ding, J Zou, J Teng
Transplantation 2018
Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II:
JA Tumlin, R Murugan, AM Deane, M Ostermann, LW Busse, KR Ham, K Kashani, HM Szerlip, JR Prowle, A Bihorac, KW Finkel, A Zarbock, LG Forni, SJ Lynch, J Jensen, S Kroll, LS Chawla, GF Tidmarsh, R Bellomo
Critical Care Medicine 2018
New roles of aldosterone and mineralocorticoid receptors in cardiovascular disease: translational and sex-specific effects
AP Davel, IZ Jaffe, RC Tostes, F Jaisser, EJ de Chantemèle
American journal of physiology. Heart and circulatory physiology 2018
Transient receptor potential channel 6 knockdown prevents apoptosis of renal tubular epithelial cells upon oxidative stress via autophagy activation
X Hou, H Xiao, Y Zhang, , M Huang, X Chen, L Birnbaumer, Y Liao
Cell Death and Disease 2018
Rodent models of AKI-CKD transition
Y Fu, C Tang, J Cai, G Chen, D Zhang, Z Dong
American journal of physiology. Renal physiology 2018
Kidney transplantation using expanded criteria deceased donors with terminal acute kidney injury: a single center experience in Korea
KJ Ko, YH Kim, MH Kim, KW Jun, KH Kwon, HS Kim, SD Kim, SC Park, JI Kim, SS Yun, IS Moon, JK Hwang
Annals of Surgical Treatment and Research 2018
Carnosol protects against renal ischemia-reperfusion injury in rats
Y Zheng, Y Zhang, Y Zheng, N Zhang
Experimental Animals 2018
Tenascin-C protects against acute kidney injury by recruiting Wnt ligands
S Chen, H Fu, S Wu, W Zhu, J Liao, X Hong, J Miao, C Luo, Y Wang, FF Hou, L Zhou, Y Liu
Kidney International 2018
Mitochondria as a therapeutic target for common pathologies
MP Murphy, RC Hartley
Nature Reviews Drug Discovery 2018
The anticonvulsive Phenhydan® suppresses extrinsic cell death
C Moerke, I Jaco, C Dewitz, T Müller, AV Jacobsen, J Gautheron, J Fritsch, J Schmitz, JH Bräsen, C Günther, JM Murphy, U Kunzendorf, P Meier, S Krautwald
Cell Death and Differentiation 2018
Micro RNA 146a-5p expression in Kidney transplant recipients with delayed graft function
P Milhoransa, CC Montanari, R Montenegro, RC Manfro
2018
Distinct patterns of transcriptional and epigenetic alterations characterize acute and chronic kidney injury
R Sharifian, DM Okamura, O Denisenko, RA Zager, A Johnson, SA Gharib, K Bomsztyk
Scientific Reports 2018
FGF10 Protects Against Renal Ischemia/Reperfusion Injury by Regulating Autophagy and Inflammatory Signaling
X Tan, H Zhu, Q Tao, L Guo, T Jiang, L Xu, R Yang, X Wei, J Wu, X Li, JS Zhang
Frontiers in Genetics 2018
Cell Death Patterns Due to Warm Ischemia or Reperfusion in Renal Tubular Epithelial Cells Originating from Human, Mouse, or the Native Hibernator Hamster
T Eleftheriadis, G Pissas, G Antoniadi, V Liakopoulos, I Stefanidis
Biology : open access journal 2018
Cell cycle shift from G0/G1 to S and G2/M phases is responsible for increased adhesion of calcium oxalate crystals on repairing renal tubular cells at injured site
S Khamchun, V Thongboonkerd
Cell Death Discovery 2018
Protective Effects of Methane-Rich Saline on Renal Ischemic-Reperfusion Injury in a Mouse Model
Y Meng, Z Jiang, N Li, Z Zhao, T Cheng, Y Yao, L Wang, Y Liu, X Deng
Medical science monitor : international medical journal of experimental and clinical research 2018
Energy handling in renal tubular epithelial cells of the hamster, a native hibernator, under warm anoxia or reoxygenation
T Eleftheriadis, G Pissas, G Antoniadi, S Golfinopoulos, V Liakopoulos, I Stefanidis
Biomedical Reports 2018
Nucleophosmin Phosphorylation as a Diagnostic and Therapeutic Target for Ischemic AKI
Z Wang, E Salih, C Igwebuike, R Mulhern, RG Bonegio, A Havasi, SC Borkan
Journal of the American Society of Nephrology : JASN 2018
Fibroblast-Specific β -catenin Signaling Dictates the Outcome of AKI
D Zhou, H Fu, L Xiao, H Mo, H Zhuo, X Tian, L Lin, J Xing, Y Liu
Journal of the American Society of Nephrology : JASN 2018
Endocan, a New Marker for Inflammation and Endothelial Dysfunction, Increases in Acute Kidney Injury
M Gunay
Northern Clinics of Istanbul 2018
A glance at black cumin (Nigella sativa) and its active constituent, thymoquinone, in ischemia: a review
Zahra Oskouei, Maryam Akaberi, Hossein Hosseinzadeh
Iranian Journal of Basic Medical Sciences 2018
Methylation-Demethylation Dynamics: Implications of Changes in Acute Kidney Injury
A Chakraborty, P Viswanathan
Analytical cellular pathology (Amsterdam) 2018
Apparent Diffusion Coefficient is a Useful Biomarker for Monitoring Adipose-Derived Mesenchymal Stem Cell Therapy of Renal Ischemic-Reperfusion Injury.
Ko SF, Yip HK, Lee CC, Lee CC, Su CH, Huang CC, Ng SH, Chen YL, Chen MC
Molecular Imaging and Biology 2018
Benefit of Mineralocorticoid Receptor Antagonism in AKI: Role of Vascular Smooth Muscle Rac1
J Barrera-Chimal, G André-Grégoire, AN Cat, SM Lechner, J Cau, S Prince, P Kolkhof, G Loirand, V Sauzeau, T Hauet, F Jaisser
Journal of the American Society of Nephrology : JASN 2017
NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity
G Stokman, L Kors, PJ Bakker, E Rampanelli, N Claessen, GJ Teske, L Butter, H Andel, MA van Weerman, PW Larsen, MC Dessing, CJ Zuurbier, SE Girardin, S Florquin, JC Leemans
Journal of Experimental Medicine 2017
Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function
L Perico, M Morigi, C Rota, M Breno, C Mele, M Noris, M Introna, C Capelli, L Longaretti, D Rottoli, S Conti, D Corna, G Remuzzi, A Benigni
Nature Communications 2017
Structural and functional diversity of collectins and ficolins and their relationship to disease
M Howard, CA Farrar, SH Sacks
Seminars in Immunopathology 2017
Complement inhibition attenuates acute kidney injury after ischemia-reperfusion and limits progression to renal fibrosis in mice
JS Danobeitia, M Ziemelis, X Ma, LJ Zitur, T Zens, PJ Chlebeck, ES van Amersfoort, LA Fernandez, NO Câmara
PloS one 2017
PGC-1α attenuates hydrogen peroxide-induced apoptotic cell death by upregulating Nrf-2 via GSK3β inactivation mediated by activated p38 in HK-2 Cells
HI Choi, HJ Kim, JS Park, IJ Kim, EH Bae, SK Ma, SW Kim
Scientific Reports 2017
Paricalcitol Pretreatment Attenuates Renal Ischemia-Reperfusion Injury via Prostaglandin E 2 Receptor EP4 Pathway
YA Hong, KJ Yang, SY Jung, KC Park, H Choi, JM Oh, SJ Lee, YK Chang, CW Park, CW Yang, SY Kim, HS Hwang
Oxidative medicine and cellular longevity 2017
Administration of mesenchymal stromal cells before renal ischemia/reperfusion attenuates kidney injury and may modulate renal lipid metabolism in rats
P Erpicum, P Rowart, L Poma, JM Krzesinski, O Detry, F Jouret
Scientific Reports 2017
Long-Term Endothelin-A Receptor Antagonism Provides Robust Renal Protection in Humanized Sickle Cell Disease Mice
M Kasztan, BM Fox, JS Speed, CD Miguel, EY Gohar, TM Townes, A Kutlar, JS Pollock, DM Pollock
Journal of the American Society of Nephrology : JASN 2017
Unique sex- and age-dependent effects in protective pathways in acute kidney injury
R Boddu, C Fan, S Rangarajan, B Sunil, S Bolisetty, LM Curtis
American journal of physiology. Renal physiology 2017
Role of intratubular pressure during the ischemic phase in acute kidney injury
J Wei, J Song, S Jiang, G Zhang, D Wheeler, J Zhang, S Wang, EY Lai, L Wang, J Buggs, R Liu
American journal of physiology. Renal physiology 2017
Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion
C Xiong, X Zang, X Zhou, L Liu, MV Masucci, J Tang, X Li, N Liu, G Bayliss, TC Zhao, S Zhuang
Oncotarget 2017
Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress
T Yang, XM Zhang, L Tarnawski, M Peleli, Z Zhuge, N Terrando, RA Harris, PS Olofsson, E Larsson, AE Persson, JO Lundberg, E Weitzberg, M Carlstrom
Redox Biology 2017
Adipose-derived mesenchymal stem cells employed exosomes to attenuate AKI-CKD transition through tubular epithelial cell dependent Sox9 activation
F Zhu, OL Shin, G Pei, Z Hu, J Yang, H Zhu, M Wang, J Mou, J Sun, Y Wang, Q Yang, Z Zhao, H Xu, H Gao, W Yao, X Luo, W Liao, G Xu, R Zeng, Y Yao
Oncotarget 2017
Human vascular progenitor cells derived from renal arteries are endothelial-like and assist in the repair of injured renal capillary networks
P Pang, M Abbott, SL Chang, M Abdi, N Chauhan, M Mistri, J Ghofrani, QA Fucci, C Walker, C Leonardi, S Grady, A Halim, R Hoffman, T Lu, H Cao, SG Tullius, S Malek, S Kumar, G Steele, A Kibel, BS Freedman, SS Waikar, AM Siedlecki
Kidney International 2017
Specific expression of heme oxygenase-1 by myeloid cells modulates renal ischemia-reperfusion injury
M Rossi, A Thierry, S Delbauve, N Preyat, MP Soares, T Roumeguère, O Leo, V Flamand, AL Moine, JM Hougardy
Scientific Reports 2017
The role of extracellular histone in organ injury
E Silk, H Zhao, H Weng, D Ma
Cell Death and Disease 2017
Single emergency room measurement of neutrophil/lymphocyte ratio for early detection of acute kidney injury (AKI)
MA Alfeilat, I Slotki, L Shavit
Internal and Emergency Medicine 2017
Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critical ill patients?
A Dewitte, S Lepreux, J Villeneuve, C Rigothier, C Combe, A Ouattara, J Ripoche
Annals of Intensive Care 2017
Fibroblast growth factor 2 protects against renal ischaemia/reperfusion injury by attenuating mitochondrial damage and proinflammatory signalling
XH Tan, XM Zheng, LX Yu, J He, HM Zhu, XP Ge, XL Ren, FQ Ye, S Bellusci, J Xiao, XK Li, JS Zhang
Journal of Cellular and Molecular Medicine 2017
Pharmacological Inhibition of PTEN Aggravates Acute Kidney Injury
J Zhou, L Jia, Z Hu, Y Wang
Scientific Reports 2017
Urinary Mitochondrial DNA Level as a Biomarker of Acute Kidney Injury Severity
PW Ho, WF Pang, CC Luk, JK Ng, KM Chow, BC Kwan, PK Li, CC Szeto
Kidney Diseases 2017
An intracellular matrix metalloproteinase-2 isoform induces tubular regulated necrosis: implications for acute kidney injury
CS Ceron, C Baligand, S Joshi, S Wanga, PM Cowley, JP Walker, SH Song, R Mahimkar, AJ Baker, RL Raffai, ZJ Wang, DH Lovett
American journal of physiology. Renal physiology 2017
Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases
AV Cybulsky
Nature Reviews Nephrology 2017
The exciting “bench to bedside” journey of cell therapies for acute kidney injury and renal transplantation
S Dellepiane, D Medica, AD Quercia, V Cantaluppi
Journal of Nephrology 2017
Serum Iron Protects from Renal Postischemic Injury
C Vaugier, MT Amano, JM Chemouny, M Dussiot, C Berrou, M Matignon, SB Mkaddem, PH Wang, A Fricot, TT Maciel, D Grapton, JR Mathieu, C Beaumont, MN Peraldi, C Peyssonnaux, L Mesnard, E Daugas, F Vrtovsnik, RC Monteiro, O Hermine, YZ Ginzburg, M Benhamou, NO Camara, M Flamant, IC Moura
Journal of the American Society of Nephrology : JASN 2017
Renal Tubular Cell-Derived Extracellular Vesicles Accelerate the Recovery of Established Renal Ischemia Reperfusion Injury
JH Dominguez, Y Liu, H Gao, JM Dominguez, D Xie, KJ Kelly
Journal of the American Society of Nephrology : JASN 2017
A signature of renal stress resistance induced by short-term dietary restriction, fasting, and protein restriction
F Jongbloed, TC Saat, M Verweij, C Payan-Gomez, JH Hoeijmakers, S Engel, CT van Oostrom, G Ambagtsheer, S Imholz, JL Pennings, H Steeg, JN IJzermans, ME Dollé, RW de Bruin
Scientific Reports 2017
Stop adding insult to injury—identifying and managing risk factors for the progression of acute kidney injury in children
W Hayes
Pediatric Nephrology 2017
Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney injury
CE Rodrigues, JM Capcha, AC de Bragança, TR Sanches, PQ Gouveia, PA de Oliveira, DM Malheiros, RA Volpini, MA Santinho, BA Santana, RT Calado, IL Noronha, L Andrade
Stem Cell Research & Therapy 2017
Osteopontin Blockade Attenuates Renal Injury After Ischemia Reperfusion by Inhibiting NK Cell Infiltration:
C Cen, M Aziz, WL Yang, JM Nicastro, GF Coppa, P Wang
Shock 2017
Fumarase activity: an in vivo and in vitro biomarker for acute kidney injury
PM Nielsen, A Eldirdiri, LB Bertelsen, HS Jørgensen, JH Ardenkjaer-Larsen, C Laustsen
Scientific Reports 2017
Urinary MicroRNA-30c-5p and MicroRNA-192-5p as potential biomarkers of ischemia–reperfusion-induced kidney injury
YF Zou, D Wen, Q Zhao, PY Shen, H Shi, Q Zhao, YX Chen, W Zhang
Experimental biology and medicine (Maywood, N.J.) 2017
Hyperuricemia increases the risk of acute kidney injury: a systematic review and meta-analysis
X Xu, J Hu, N Song, R Chen, T Zhang, X Ding
BMC Nephrology 2017
TRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury
JD Pressly, T Hama, SO Brien, KR Regner, F Park
Scientific Reports 2017
The effect of hypericum perforatum on kidney ischemia/reperfusion damage
M Cakir, H Duzova, I Baysal, CC Gül, G Kuşcu, F Kutluk, H Çakin, Ş Şeker, E İlbeği, S Uslu, U Avci, S Demir, C Akinci, S Atli
Renal Failure 2017
Comparison of human adipose stromal vascular fraction and adipose-derived mesenchymal stem cells for the attenuation of acute renal ischemia/reperfusion injury
L Zhou, Q Song, J Shen, L Xu, Z Xu, R Wu, Y Ge, J Zhu, J Wu, Q Dou, R Jia
Scientific Reports 2017
Kidney Injury and Repair Biomarkers in Marathon Runners
SG Mansour, G Verma, RW Pata, TG Martin, MA Perazella, CR Parikh
American Journal of Kidney Diseases 2017
Fast renal decline to end-stage renal disease: an unrecognized feature of nephropathy in diabetes
AS Krolewski, J Skupien, P Rossing, JH Warram
Kidney International 2017
Quantified kidney echogenicity in mice with renal ischemia reperfusion injury: evaluation as a noninvasive biomarker of acute kidney injury
S Murata, N Sugiyama, K Maemura, Y Otsuki
Medical Molecular Morphology 2017
Preconditioning of primary human renal proximal tubular epithelial cells without tryptophan increases survival under hypoxia by inducing autophagy
T Eleftheriadis, G Pissas, M Sounidaki, N Antoniadis, G Antoniadi, V Liakopoulos, I Stefanidis
International Urology and Nephrology 2017
Comparison of normothermic and hypothermic perfusion in porcine kidneys donated after cardiac death
MF Blum, Q Liu, B Soliman, P Dreher, T Okamoto, ED Poggio, DA Goldfarb, WM Baldwin, C Quintini
Journal of Surgical Research 2017
Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target
O Elshenawy, S Shoieb, A Mohamed, A El-Kadi
Pharmaceutics 2017
Urinary neprilysin in the critically ill patient
S Pajenda, K Mechtler, L Wagner
BMC Nephrology 2017
Mesenchymal stem cells correct haemodynamic dysfunction associated with liver injury after extended resection in a pig model
HM Tautenhahn, S Brückner, C Uder, S Erler, M Hempel, M Bergen, J Brach, S Winkler, F Pankow, C Gittel, M Baunack, U Lange, J Broschewitz, M Dollinger, M Bartels, U Pietsch, K Amann, B Christ
Scientific Reports 2017
Head-to-head comparison of structurally unrelated dipeptidyl peptidase 4 inhibitors in the setting of renal ischemia reperfusion injury: DPP4 inhibition in acute kidney injury
C Reichetzeder, K Websky, O Tsuprykov, AM Samarin, LG Falke, SE Putra, AA Hasan, V Antonenko, C Curato, J Rippmann, T Klein, B Hocher
British Journal of Pharmacology 2017
Perfusion of isolated rat kidney with Mesenchymal Stromal Cells/Extracellular Vesicles prevents ischaemic injury
M Gregorini, V Corradetti, EF Pattonieri, C Rocca, S Milanesi, A Peloso, S Canevari, LD Cecco, M Dugo, MA Avanzini, M Mantelli, M Maestri, P Esposito, S Bruno, C Libetta, AD Canton, T Rampino
Journal of Cellular and Molecular Medicine 2017
Effects of chronic alcohol exposure on ischemia–reperfusion-induced acute kidney injury in mice: the role of β-arrestin 2 and glycogen synthase kinase 3
L Wang, Y Zhu, L Wang, J Hou, Y Gao, L Shen, J Zhang
Experimental & molecular medicine 2017
Issues of Acute Kidney Injury Staging and Management in Sepsis and Critical Illness: A Narrative Review
C Nusshag, M Weigand, M Zeier, C Morath, T Brenner
International journal of molecular sciences 2017
Renal Protection Mediated by Hypoxia Inducible Factor-1α Depends on Proangiogenesis Function of miR-21 by Targeting Thrombospondin 1:
X Xu, N Song, X Zhang, X Jiao, J Hu, M Liang, J Teng, X Ding
Transplantation 2017
Engineered extracellular matrices with controlled mechanics modulate renal proximal tubular cell epithelialization
JA Beamish, E Chen, AJ Putnam, SR Singh
PloS one 2017
Cell-cycle arrest biomarkers in urine to predict acute kidney injury in septic and non-septic critically ill patients
M Cuartero, J Ballús, J Sabater, X Pérez, N Nin, J Ordonez-Llanos, AJ Betbesé
Annals of Intensive Care 2017
CKJ Review Angiotensinogen as a biomarker of acute kidney injury
SH Aqeel, A Sanchez, D Batlle
Clinical Kidney Journal 2017
Farnesoid X receptor activation protects the kidney from ischemia-reperfusion damage
Z Gai, L Chu, Z Xu, X Song, D Sun, GA Kullak-Ublick
Scientific Reports 2017
Gender Differences in the Acute Kidney Injury to Chronic Kidney Disease Transition
I Lima-Posada, C Portas-Cortés, R Pérez-Villalva, F Fontana, R Rodríguez-Romo, R Prieto, A Sánchez-Navarro, GL Rodríguez-González, G Gamba, E Zambrano, NA Bobadilla
Scientific Reports 2017
Fate of Neutrophils during the Recovery Phase of Ischemia/Reperfusion Induced Acute Kidney Injury
W Cho, JY Song, SW Oh, MG Kim, YS Ko, HY Lee, SK Jo
Journal of Korean Medical Science 2017
Protective outcomes of low-dose doxycycline on renal function of Wistar rats subjected to acute ischemia/reperfusion injury
AL Cortes, SR Gonsalez, LS Rioja, SS Oliveira, AL Santos, MC Prieto, PA Melo, LS Lara
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2017
Endothelial STAT3 Modulates Protective Mechanisms in a Mouse Ischemia-Reperfusion Model of Acute Kidney Injury
S Dube, T Matam, J Yen, HE Mang, PC Dagher, T Hato, TA Sutton
Journal of Immunology Research 2017
Tissue regeneration using endothelial colony-forming cells: promising cells for vascular repair
K Banno, MC Yoder
Pediatric Research 2017
Quantitative Three-Dimensional Tissue Cytometry to Study Kidney Tissue and Resident Immune Cells
S Winfree, S Khan, R Micanovic, MT Eadon, KJ Kelly, TA Sutton, CL Phillips, KW Dunn, TM El-Achkar
Journal of the American Society of Nephrology : JASN 2017
Pharmacologic Approaches to Improve Mitochondrial Function in AKI and CKD
HH Szeto
Journal of the American Society of Nephrology : JASN 2017
Role of miR‑21 on vascular endothelial cells in the protective effect of renal delayed ischemic preconditioning
X Xu, X Jiao, N Song, W Luo, M Liang, X Ding, J Teng
Molecular medicine reports 2017
Risk factors for continuous renal replacement therapy after surgical repair of type A aortic dissection
HB Wu, WG Ma, HL Zhao, J Zheng, JR Li, O Liu, LZ Sun
Journal of Thoracic Disease 2017
Neutrophil Gelatinase-Associated Lipocalin Levels During Pneumoperitoneum
M Kiseli, GS Caglar, H Yilmaz, AY Gursoy, T Candar, EG Pabuccu, ZK Bengisun, F Tuzuner
JSLS : Journal of the Society of Laparoendoscopic Surgeons 2017
Quercetin nanoparticle complex attenuated diabetic nephropathy via regulating the expression level of ICAM-1 on endothelium
F Tong, S Liu, B Yan, X Li, S Ruan, S Yang
International Journal of Nanomedicine 2017
MicroRNA-30c-5p ameliorates hypoxia-reoxygenation-induced tubular epithelial cell injury via HIF1α stabilization by targeting SOCS3
YF Zou, WT Liao, ZJ Fu, Q Zhao, YX Chen, W Zhang
Oncotarget 2017
Unilateral nephrectomy diminishes ischemic acute kidney injury through enhanced perfusion and reduced pro-inflammatory and pro-fibrotic responses
C Kierulf-Lassen, PM Nielsen, H Qi, M Damgaard, C Laustsen, M Pedersen, S Krag, H Birn, R Nørregaard, B Jespersen, JA Joles
PloS one 2017
Extracellular vesicles from human-induced pluripotent stem cell-derived mesenchymal stromal cells (hiPSC-MSCs) protect against renal ischemia/reperfusion injury via delivering specificity protein (SP1) and transcriptional activating of sphingosine kinase 1 and inhibiting necroptosis
X Yuan, D Li, X Chen, C Han, L Xu, T Huang, Z Dong, M Zhang
Cell Death and Disease 2017
Role of microRNA in the detection, progression, and intervention of acute kidney injury
YF Zou, W Zhang
Experimental biology and medicine (Maywood, N.J.) 2017
Vasa recta pericyte density is negatively associated with vascular congestion in the renal medulla following ischemia reperfusion in rats
GR Crislip, PM OConnor, Q Wei, JC Sullivan
American journal of physiology. Renal physiology 2017
RTA-408 Protects Kidney from Ischemia-Reperfusion Injury in Mice via Activating Nrf2 and Downstream GSH Biosynthesis Gene
P Han, Z Qin, J Tang, Z Xu, R Li, X Jiang, C Yang, Q Xing, X Qi, M Tang, J Zhang, B Shen, W Wang, C Qin, W Zhang
Oxidative medicine and cellular longevity 2017
Renoprotective effect of erythropoietin via modulation of the STAT6/MAPK/NF-κB pathway in ischemia/reperfusion injury after renal transplantation
J Zhang, D Zhao, N Na, H Li, B Miao, L Hong, Z Huang
International journal of molecular medicine 2017
Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels
Y Kenig-Kozlovsky, RP Scott, T Onay, IA Carota, BR Thomson, HJ Gil, V Ramirez, S Yamaguchi, CE Tanna, S Heinen, C Wu, RV Stan, JD Klein, JM Sands, G Oliver, SE Quaggin
Journal of the American Society of Nephrology : JASN 2017
Selective Cannabinoid 2 Receptor Stimulation Reduces Tubular Epithelial Cell Damage after Renal Ischemia-Reperfusion Injury
JD Pressly, SM Mustafa, AH Adibi, S Alghamdi, P Pandey, KK Roy, RJ Doerksen, BM Moore, F Park
The Journal of pharmacology and experimental therapeutics 2017
Dead cell phagocytosis and innate immune checkpoint.
Yoon KW
BMB Reports 2017
Wnt Signaling in Kidney Development and Disease
Wang Y, Zhou CJ, Liu Y
Progress in molecular biology and translational science 2017
Protective Role for Antioxidants in Acute Kidney Disease.
Dennis JM, Witting PK
Nutrients 2017
Chronic intermittent hypoxia exposure induces kidney injury in growing rats.
Poonit ND, Zhang YC, Ye CY, Cai HL, Yu CY, Li T, Cai XH
Sleep & breathing = Schlaf & Atmung 2017
Assessment of acute kidney injury with T1 mapping MRI following solid organ transplantation.
Peperhove M, Vo Chieu VD, Jang MS, Gutberlet M, Hartung D, Tewes S, Warnecke G, Fegbeutel C, Haverich A, Gwinner W, Lehner F, Bräsen JH, Haller H, Wacker F, Gueler F, Hueper K
European Radiology 2017
Vagus Nerve-Mediated Protection from Kidney Ischemia-Reperfusion Injury through α7nAChR+ Splenocytes
Tsuyoshi Inoue, Chikara Abe, Sung-Sang Sung, Stefan Moscalu, Jakub Jankowski, Liping Huang, Hong Ye, Diane L. Rosin, Patrice Guyenet, Mark D. Okusa
Journal of Clinical Investigation 2016
Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury
Conrad Farrar, David Tran, Ke Li, Weiju Wu, Qi Peng, Wilhelm Schwaeble, Wuding Zhou, Steven H. Sacks
Journal of Clinical Investigation 2016
Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney
Yuki Sato, Akiko Mii, Yoko Hamazaki, Harumi Fujita, Hirosuke Nakata, Kyoko Masuda, Shingo Nishiyama, Shinsuke Shibuya, Hironori Haga, Osamu Ogawa, Akira Shimizu, Shuh Narumiya, Tsuneyasu Kaisho, Makoto Arita, Masashi Yanagisawa, Masayuki Miyasaka, Kumar Sharma, Nagahiro Minato, Hiroshi Kawamoto, Motoko Yanagita
JCI Insight 2016
ADAM17 substrate release in proximal tubule drives kidney fibrosis
Eirini Kefaloyianni, Muthu Lakshmi Muthu, Jakob Kaeppler, Xiaoming Sun, Venkata Sabbisetti, Athena Chalaris, Stefan Rose-John, Eitan Wong, Irit Sagi, Sushrut S. Waikar, Helmut G. Rennke, Benjamin D. Humphreys, Joseph V. Bonventre, Andreas Herrlich
JCI Insight 2016
Depletion of Gut Microbiota Protects against Renal Ischemia-Reperfusion Injury
D Emal, E Rampanelli, I Stroo, LM Butter, GJ Teske, N Claessen, G Stokman, S Florquin, JC Leemans, MC Dessing
Journal of the American Society of Nephrology : JASN 2016
Acute Kidney Injury
A Zuk, JV Bonventre
Annual Review of Medicine 2016
Autophagy, Innate Immunity and Tissue Repair in Acute Kidney Injury
P Duann, E Lianos, J Ma, PH Lin
International journal of molecular sciences 2016
Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog
M Edeling, G Ragi, S Huang, H Pavenstädt, K Susztak
Nature Reviews Nephrology 2016
Valproic Acid Prevents Renal Dysfunction and Inflammation in the Ischemia-Reperfusion Injury Model
EC Costalonga, FM Silva, IL Noronha
BioMed Research International 2016
RANTES mediates kidney ischemia reperfusion injury through a possible role of HIF-1α and LncRNA PRINS
TM Yu, K Palanisamy, KT Sun, YJ Day, KH Shu, IK Wang, WC Shyu, P Chen, YL Chen, CY Li
Scientific Reports 2016
Dipyridamole attenuates ischemia reperfusion induced acute kidney injury through adenosinergic A1 and A2A receptor agonism in rats
N Puri, V Mohey, M Singh, T Kaur, D Pathak, HS Buttar, AP Singh
Naunyn-Schmiedeberg's Archives of Pharmacology 2016
Preischemic Administration of Nonexpanded Adipose Stromal Vascular Fraction Attenuates Acute Renal Ischemia/Reperfusion Injury and Fibrosis
L Zhou, L Xu, J Shen, Q Song, R Wu, Y Ge, H Xin, J Zhu, J Wu, R Jia
Stem Cells Translational Medicine 2016
Renoprotective approaches and strategies in acute kidney injury
Y Yang, M Song, Y Liu, H Liu, L Sun, Y Peng, F Liu, MA Venkatachalam, Z Dong
Pharmacology & Therapeutics 2016
The role of long-term label-retaining cells in the regeneration of adult mouse kidney after ischemia/reperfusion injury
X Liu, H Liu, L Sun, Z Chen, H Nie, A Sun, G Liu, G Guan
Stem Cell Research & Therapy 2016
Implications of dynamic changes in miR-192 expression in ischemic acute kidney injury
L Zhang, Y Xu, S Xue, X Wang, H Dai, J Qian, Z Ni, Y Yan
International Urology and Nephrology 2016
Hydrogen Sulfide in Renal Physiology and Disease
D Feliers, HJ Lee, BS Kasinath
Antioxidants & Redox Signaling 2016
Kidney injury molecule-1 (KIM-1) mediates renal epithelial cell repair via ERK MAPK signaling pathway
Z Zhang, CX Cai
Molecular and Cellular Biochemistry 2016
Mitochondria-Targeted Antioxidants: Future Perspectives in Kidney Ischemia Reperfusion Injury
A Kezic, I Spasojevic, V Lezaic, M Bajcetic
Oxidative medicine and cellular longevity 2016
MicroRNA-489 Induction by Hypoxia-Inducible Factor-1 Protects against Ischemic Kidney Injury
Q Wei, Y Liu, P Liu, J Hao, M Liang, Q Mi, JK Chen, Z Dong
Journal of the American Society of Nephrology : JASN 2016
Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation
A Tammaro, J Kers, D Emal, I Stroo, GJ Teske, LM Butter, N Claessen, J Damman, M Derive, G Navis, S Florquin, JC Leemans, MC Dessing
Scientific Reports 2016
Macrophage-derived Lipocalin-2 contributes to ischemic resistance mechanisms by protecting from renal injury
M Jung, B Brüne, G Hotter, A Sola
Scientific Reports 2016
Progression of chronic kidney disease after acute kidney injury
P Devarajan, JL Jefferies
Progress in Pediatric Cardiology 2016
Expression and Function of Interleukin-1β-Induced Neutrophil Gelatinase-Associated Lipocalin in Renal Tubular Cells
T Konno, R Nakano, R Mamiya, H Tsuchiya, T Kitanaka, S Namba, N Kitanaka, K Okabayashi, T Narita, H Sugiya, B Bussolati
PloS one 2016
miR-146a is essential for lipopolysaccharide (LPS)-induced cross-tolerance against kidney ischemia/reperfusion injury in mice
Y Dai, P Jia, Y Fang, H Liu, X Jiao, JC He, X Ding
Scientific Reports 2016
Acute kidney injury and chronic kidney disease: From the laboratory to the clinic
DA Ferenbach, JV Bonventre
Néphrologie & Thérapeutique 2016
Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice
S Arai, K Kitada, T Yamazaki, R Takai, X Zhang, Y Tsugawa, R Sugisawa, A Matsumoto, M Mori, Y Yoshihara, K Doi, N Maehara, S Kusunoki, A Takahata, E Noiri, Y Suzuki, N Yahagi, A Nishiyama, L Gunaratnam, T Takano, T Miyazaki
Nature Medicine 2016
Impact of feline AIM on the susceptibility of cats to renal disease
R Sugisawa, E Hiramoto, S Matsuoka, S Iwai, R Takai, T Yamazaki, N Mori, Y Okada, N Takeda, K Yamamura, T Arai, S Arai, T Miyazaki
Scientific Reports 2016
Wnt/ -catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration
D Bastakoty, PP Young
The FASEB Journal 2016
Hepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells
M Omata, Y Doke, C Yamada, K Kawashima, R Sho, K Enomoto, M Furuya, N Inomata, JC Dussaule
PloS one 2016
Cellular and Molecular Mechanisms of AKI
A Agarwal, Z Dong, R Harris, P Murray, SM Parikh, MH Rosner, JA Kellum, C Ronco
Journal of the American Society of Nephrology : JASN 2016
Induction of microRNA-17-5p by p53 protects against renal ischemia-reperfusion injury by targeting death receptor 6
J Hao, Q Wei, S Mei, L Li, Y Su, C Mei, Z Dong
Kidney International 2016
Mesenchymal Stromal Cells Derived Extracellular Vesicles Ameliorate Acute Renal Ischemia Reperfusion Injury by Inhibition of Mitochondrial Fission through miR-30
D Gu, X Zou, G Ju, G Zhang, E Bao, Y Zhu
Stem Cells International 2016
The kidney regulates regeneration, but don’t upset the balance
S Brandt, PR Mertens
International Urology and Nephrology 2016
Role of kidney injury in sepsis
K Doi
Journal of Intensive Care 2016
Deficiency of cold-inducible ribonucleic acid-binding protein reduces renal injury after ischemia-reperfusion
C Cen, WL Yang, HT Yen, JM Nicastro, GF Coppa, P Wang
Surgery 2016
Real-time urinary electrolyte monitoring after furosemide administration in surgical ICU patients with normal renal function
L Zazzeron, D Ottolina, E Scotti, M Ferrari, P Bruzzone, S Sibilla, C Marenghi, L Gattinoni, P Caironi
Annals of Intensive Care 2016
Short-Term Preoperative Calorie and Protein Restriction Is Feasible in Healthy Kidney Donors and Morbidly Obese Patients Scheduled for Surgery
F Jongbloed, R Bruin, R Klaassen, P Beekhof, H Steeg, F Dor, E der Harst, M Dollé, J IJzermans
Nutrients 2016
Acute kidney injury in the perioperative period and in intensive care units (excluding renal replacement therapies)
C Ichai, C Vinsonneau, B Souweine, F Armando, E Canet, C Clech, JM Constantin, M Darmon, J Duranteau, T Gaillot, A Garnier, L Jacob, O Joannes-Boyau, L Juillard, D Journois, A Lautrette, L Muller, M Legrand, N Lerolle, T Rimmelé, E Rondeau, F Tamion, Y Walrave, L Velly
Anaesthesia Critical Care & Pain Medicine 2016
Stress Response Gene Nupr1 Alleviates Cyclosporin A Nephrotoxicity In Vivo
P Galichon, A Bataille, S Vandermeersch, M Wetzstein, YC Xu-Dubois, D Legouis, A Hertig, D Buob, S Placier, N Bige, G Lefevre, C Jouanneau, C Martin, JL Iovanna, E Rondeau
Journal of the American Society of Nephrology : JASN 2016
Tubular Epithelial NF- B Activity Regulates Ischemic AKI
L Marko, E Vigolo, C Hinze, JK Park, G Roel, A Balogh, M Choi, A Wubken, J Cording, IE Blasig, FC Luft, C Scheidereit, KM Schmidt-Ott, R Schmidt-Ullrich, DN Muller
Journal of the American Society of Nephrology : JASN 2016
Endothelial Glycocalyx: Not Just a Sugar Coat
L Li, JV Bonventre
American journal of respiratory and critical care medicine 2016
High-resolution renal perfusion mapping using contrast-enhanced ultrasonography in ischemia-reperfusion injury monitors changes in renal microperfusion
K Fischer, FC Meral, Y Zhang, MG Vangel, FA Jolesz, T Ichimura, JV Bonventre
Kidney International 2016
Relationship of clusterin with renal inflammation and fibrosis after the recovery phase of ischemia-reperfusion injury
J Guo, Q Guan, X Liu, H Wang, ME Gleave, CY Nguan, C Du
BMC Nephrology 2016
Improving the outcome of kidney transplantation by ameliorating renal ischemia reperfusion injury: lost in translation?
TC Saat, EK van Akker, JN IJzermans, FJ Dor, RW de Bruin
Journal of Translational Medicine 2016
Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury
P Cocchiaro, C Fox, NW Tregidgo, R Howarth, KM Wood, GR Situmorang, LM Pavone, NS Sheerin, A Moles
Scientific Reports 2016
Increased Renal 2-Arachidonoylglycerol Level Is Associated with Improved Renal Function in a Mouse Model of Acute Kidney Injury
H Moradi, F Oveisi, E Khanifar, G Moreno-Sanz, ND Vaziri, D Piomelli
Cannabis and Cannabinoid Research 2016
The Role of Activin A and B and the Benefit of Follistatin Treatment in Renal Ischemia-Reperfusion Injury in Mice:
DY Fang, B Lu, S Hayward, DM de Kretser, PJ Cowan, KM Dwyer
Transplantation Direct 2016
Association of markers of endothelial dysregulation Ang1 and Ang2 with acute kidney injury in critically ill patients
C Robinson-Cohen, R Katz, BL Price, S Harju-Baker, C Mikacenic, J Himmelfarb, WC Liles, MM Wurfel
Critical Care 2016
Proteasome or immunoproteasome inhibitors cause apoptosis in human renal tubular epithelial cells under normoxic and hypoxic conditions
T Eleftheriadis, G Pissas, G Antoniadi, V Liakopoulos, I Stefanidis
International Urology and Nephrology 2016
C-reactive protein promotes acute kidney injury via Smad3-dependent inhibition of CDK2/cyclin E
W Lai, Y Tang, XR Huang, PM Tang, A Xu, AJ Szalai, T Lou, HY Lan
Kidney International 2016
Global miRNA expression is temporally correlated with acute kidney injury in mice
R Cui, J Xu, X Chen, W Zhu
PeerJ 2016
The Synthetic Tie2 Agonist Peptide Vasculotide Protects Renal Vascular Barrier Function In Experimental Acute Kidney Injury
E Rübig, J Stypmann, PV Slyke, DJ Dumont, T Spieker, K Buscher, S Reuter, T Goerge, H Pavenstädt, P Kümpers
Scientific Reports 2016
Nanomedicines for kidney diseases
RM Williams, EA Jaimes, DA Heller
Kidney International 2016
Remote ischemic perconditioning attenuates ischemia/reperfusion‐induced downregulation of AQP2 in rat kidney
ML Kristensen, C KierulfLassen, PM Nielsen, S Krag, H Birn, LN Nejsum, R Nørregaard
Physiological Reports 2016
Genetic Ablation of Calcium-independent Phospholipase A 2 γ Induces Glomerular Injury in Mice
H Elimam, J Papillon, DR Kaufman, J Guillemette, L Aoudjit, RW Gross, T Takano, AV Cybulsky
The Journal of biological chemistry 2016
Unilateral Renal Ischemia-Reperfusion as a Robust Model for Acute to Chronic Kidney Injury in Mice
NL Clef, A Verhulst, PC DHaese, BA Vervaet, C Chatziantoniou
PloS one 2016
Major comorbid disease processes associated with increased incidence of acute kidney injury
S Farooqi, JG Dickhout
World Journal of Nephrology 2016
Insights into kidney stem cell development and regeneration using zebrafish
BE Drummond
World journal of stem cells 2016
Renal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient Mice
Y Zhu, M Blum, U Hoff, T Wesser, M Fechner, C Westphal, D Gürgen, RA Catar, A Philippe, K Wu, G Bubalo, M Rothe, SM Weldon, D Dragun, WH Schunck, S Liebner
PloS one 2016
DNA damage response in nephrotoxic and ischemic kidney injury
M Yan, C Tang, Z Ma, S Huang, Z Dong
Toxicology and Applied Pharmacology 2016
GSPE Inhibits HMGB1 Release, Attenuating Renal IR-Induced Acute Renal Injury and Chronic Renal Fibrosis
J Zhan, K Wang, C Zhang, C Zhang, Y Li, Y Zhang, X Chang, Q Zhou, Y Yao, Y Liu, G Xu
International journal of molecular sciences 2016
Inhaled nitric oxide and the risk of renal dysfunction in patients with acute respiratory distress syndrome: a propensity-matched cohort study
SY Ruan, HY Wu, HH Lin, HD Wu, CJ Yu, MS Lai
Critical Care 2016
Ouabain Contributes to Kidney Damage in a Rat Model of Renal Ischemia-Reperfusion Injury
L Villa, R Buono, M Ferrandi, I Molinari, F Benigni, A Bettiga, G Colciago, M Ikehata, E Messaggio, M Rastaldi, F Montorsi, A Salonia, P Manunta
International journal of molecular sciences 2016
Nuclear Magnetic Resonance Metabolomic Profiling of Mouse Kidney, Urine and Serum Following Renal Ischemia/Reperfusion Injury
F Jouret, J Leenders, L Poma, JO Defraigne, JM Krzesinski, P Tullio, D Monleon
PloS one 2016
Response gene to complement 32 regulates the G2/M phase checkpoint during renal tubular epithelial cell repair
Y Shen, H Liu, L Sun, X Niu, X Kuang, P Wang, S Hao, W Huang
Cellular & Molecular Biology Letters 2016
Enhanced protection against renal ischemia–reperfusion injury with combined melatonin and exendin-4 in a rodent model
YC Chang, SY Hsu, CC Yang, PH Sung, YL Chen, TH Huang, GS Kao, SY Chen, KH Chen, HJ Chiang, HK Yip, FY Lee
Experimental biology and medicine (Maywood, N.J.) 2016
Involvement of peroxisome proliferator activated receptor-γ in the anti-inflammatory effects of atorvastatin in oxygen-glucose deprivation/reperfusion-stimulated RAW264.7 murine macrophages
HY Li, YY Su, YF Zhang, ZQ Liu, BJ Hua
Molecular medicine reports 2016
Unique Transcriptional Programs Identify Subtypes of AKI
K Xu, P Rosenstiel, N Paragas, C Hinze, X Gao, TH Shen, M Werth, C Forster, R Deng, E Bruck, RW Boles, A Tornato, T Gopal, M Jones, J Konig, J Stauber, V DAgati, H Erdjument-Bromage, S Saggi, G Wagener, KM Schmidt-Ott, N Tatonetti, P Tempst, JA Oliver, P Guarnieri, J Barasch
Journal of the American Society of Nephrology : JASN 2016
Predictors and in-hospital outcomes of preoperative acute kidney injury in patients with type A acute aortic dissection
Xiao Wang, Hong-Mei Ren, Chun-Yan Hu, Bin Que, Hui Ai, Chun-Mei Wang, Li-Zhong Sun, Shao-Ping Nie
Journal of Geriatric Cardiology 2016
Histological study on the protective effect of endogenous stem-cell mobilization in Adriamycin-induced chronic nephropathy in rats
EM Sadek, NM Salama, DI Ismail, AA Elshafei
Journal of Microscopy and Ultrastructure 2016
Vasopressin analog terlipressin attenuates kidney injury in hemorrhagic shock
LU de Castro, KK Ida, DA Otsuki, TR Sanches, RA Volpini, E da Silva Borges, LM Malbouisson, L Andrade
2016
Acute kidney injury: current concepts and new insights
Koza Y
Journal of Injury and Violence Research 2016
Sirtuin3 and mitochondrial dynamics: new perspectives in acute kidney injury
Marina Morigi, Luca Perico, Cinzia Rota, Lorena Longaretti, Sara Conti, Daniela Rottoli, Rubina Novelli, Giuseppe Remuzzi, Ariela Benigni
Journal of Clinical Investigation 2015
KIM-1/TIM-1 mediated-phagocytosis reduces acute injury to the kidney
Li Yang, Craig Brooks, Sheng Xiao, Venkata Sabbisetti, Melissa Yeung, Li-Li Hsiao, Takaharu Ichimura, Vijay Kuchroo, Joseph V. Bonventre
Journal of Clinical Investigation 2015
IL-34 Mediates Acute Kidney Injury Worsening Subsequent Chronic Kidney Disease
Jea-Hyun Baek, Rui Zeng, Julia Weinmann-Menke, M. Todd Valerius, Yukihiro Wada, Ajay Amrendra, Marco Colonna, Vicki Rubin Kelley
Journal of Clinical Investigation 2015
MicroRNA-687 Induced by Hypoxia-Inducible Factor-1 Targets Phosphatase and Tensin Homolog in Renal Ischemia-Reperfusion Injury
K Bhatt, Q Wei, N Pabla, G Dong, QS Mi, M Liang, C Mei, Z Dong
Journal of the American Society of Nephrology : JASN 2015
IKK  is involved in kidney recovery and regeneration of acute ischemia/reperfusion injury in mice through IL10-producing regulatory T cells
X Wan, LJ Hou, LY Zhang, WJ Huang, L Liu, Q Zhang, B Hu, W Chen, X Chen, CC Cao
Disease models & mechanisms 2015
Aquaporin 11 variant associates with kidney disease in type 2 diabetic patients
DP Choma, R Vanacore, H Naylor, IA Zimmerman, A Pavlichenko, A Pavlichenko, L Foye, DP Carbone, RC Harris, MM Dikov, EE Tchekneva
American journal of physiology. Renal physiology 2015
T Lymphocyte-Specific Activation of Nrf2 Protects from AKI
S Noel, MN Martina, S Bandapalle, LC Racusen, HR Potteti, AR Hamad, SP Reddy, H Rabb
Journal of the American Society of Nephrology : JASN 2015
The balance of powers: Redox regulation of fibrogenic pathways in kidney injury
DM Okamura, S Pennathur
Redox Biology 2015
Simultaneous deletion of Bax and Bak is required to prevent apoptosis and interstitial fibrosis in obstructive nephropathy
HS Jang, BJ Padanilam
American journal of physiology. Renal physiology 2015
Unilateral renal ischaemia in rats induces a rapid secretion of inflammatory markers to renal lymph and increased capillary permeability: Inflammatory mediators in renal lymph
LM Bivol, BM Iversen, M Hultström, PW Wallace, RK Reed, H Wiig, O Tenstad
The Journal of Physiology 2015
Sphingosine 1-Phosphate Receptor 3-Deficient Dendritic Cells Modulate Splenic Responses to Ischemia-Reperfusion Injury
A Bajwa, L Huang, E Kurmaeva, JC Gigliotti, H Ye, J Miller, DL Rosin, PI Lobo, MD Okusa
Journal of the American Society of Nephrology : JASN 2015
Ischemia and reperfusion injury in renal transplantation: hemodynamic and immunological paradigms
LR Requião-Moura, MS Durão, AC de Matos, A Pacheco-Silva
Einstein (São Paulo) 2015
Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD
DA Ferenbach, JV Bonventre
Nature Reviews Nephrology 2015
Adenosine 2A receptors in acute kidney injury
IS Vincent, MD Okusa
Acta physiologica (Oxford, England) 2015
Ultrasound Modulates the Splenic Neuroimmune Axis in Attenuating AKI
JC Gigliotti, L Huang, A Bajwa, H Ye, EH Mace, JA Hossack, K Kalantari, T Inoue, DL Rosin, MD Okusa
Journal of the American Society of Nephrology : JASN 2015
Progression after AKI: Understanding Maladaptive Repair Processes to Predict and Identify Therapeutic Treatments
DP Basile, JV Bonventre, R Mehta, M Nangaku, R Unwin, MH Rosner, JA Kellum, C Ronco
Journal of the American Society of Nephrology : JASN 2015
Palladin is Upregulated in Kidney Disease and Contributes to Epithelial Cell Migration After Injury
EH Chang, AH Gasim, ML Kerber, JB Patel, SA Glaubiger, RJ Falk, JC Jennette, CA Otey
Scientific Reports 2015
Kidney Regeneration: Lessons from Development
T Chiba, N Hukriede, MP de Caestecker
Current Pathobiology Reports 2015
Involvement of the Hippo pathway in regeneration and fibrogenesis after ischaemic acute kidney injury: YAP is the key effector
J Xu, PX Li, J Wu, YJ Gao, MX Yin, Y Lin, M Yang, DP Chen, HP Sun, ZB Liu, XC Gu, HL Huang, LL Fu, HM Hu, LL He, WQ Wu, ZL Fei, HB Ji, L Zhang, CL Mei
Clinical Science 2015
Proteome Analysis of Renoprotection Mediated by a Novel Cyclic Helix B Peptide in Acute Kidney Injury
C Yang, J Liu, L Li, M Hu, Y Long, X Liu, T Zhu, X Huang, S Zhao, S Liu, R Rong
Scientific Reports 2015
Telomerase deficiency delays renal recovery in mice after ischemia–reperfusion injury by impairing autophagy
H Cheng, X Fan, WE Lawson, P Paueksakon, RC Harris
Kidney International 2015
Microvesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Facilitate Tubular Epithelial Cell Dedifferentiation and Growth via Hepatocyte Growth Factor Induction
G Ju, J Cheng, L Zhong, S Wu, X Zou, G Zhang, D Gu, S Miao, Y Zhu, J Sun, T Du, B Bussolati
PloS one 2015
Failed Tubule Recovery, AKI-CKD Transition, and Kidney Disease Progression
MA Venkatachalam, JM Weinberg, W Kriz, AK Bidani
Journal of the American Society of Nephrology : JASN 2015
Targeting Endogenous Repair Pathways after AKI
BD Humphreys, V Cantaluppi, D Portilla, K Singbartl, L Yang, MH Rosner, JA Kellum, C Ronco
Journal of the American Society of Nephrology : JASN 2015
Necroinflammation in Kidney Disease
SR Mulay, A Linkermann, HJ Anders
Journal of the American Society of Nephrology : JASN 2015
Atlas of Cellular Dynamics during Zebrafish Adult Kidney Regeneration
KK McCampbell, KN Springer, RA Wingert
Stem Cells International 2015
Endogenous Toll-Like Receptor 9 Regulates AKI by Promoting Regulatory T Cell Recruitment
MA Alikhan, SA Summers, PY Gan, AJ Chan, MB Khouri, JD Ooi, JR Ghali, D Odobasic, MJ Hickey, AR Kitching, SR Holdsworth
Journal of the American Society of Nephrology : JASN 2015
Recent developments in epigenetics of acute and chronic kidney diseases
MA Reddy, R Natarajan
Kidney International 2015
Recent advances in understanding of chronic kidney disease
J Yamaguchi, T Tanaka, M Nangaku
F1000Research 2015
MG53-mediated cell membrane repair protects against acute kidney injury
P Duann, H Li, P Lin, T Tan, Z Wang, K Chen, X Zhou, K Gumpper, H Zhu, T Ludwig, PJ Mohler, B Rovin, WT Abraham, C Zeng, J Ma
Science Translational Medicine 2015
Update on ischemia-reperfusion injury in kidney transplantation: Pathogenesis and treatment
Maurizio Salvadori, Giuseppina Rosso, Elisabetta Bertoni
World Journal of Transplantation 2015
G protein α 12 (Gα 12 ) is a negative regulator of kidney injury molecule-1-mediated efferocytosis
OZ Ismail, X Zhang, JV Bonventre, L Gunaratnam
American journal of physiology. Renal physiology 2015
No Effect of Remote Ischemic Conditioning Strategies on Recovery from Renal Ischemia-Reperfusion Injury and Protective Molecular Mediators
C Kierulf-Lassen, ML Kristensen, H Birn, B Jespersen, R Nørregaard, F Gallyas
PloS one 2015
SUMOylation occurs in acute kidney injury and plays a cytoprotective role
C Guo, Q Wei, Y Su, Z Dong
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2015
Tubular cross talk in acute kidney injury: a story of sense and sensibility
TM El-Achkar, PC Dagher
American journal of physiology. Renal physiology 2015
Differential Ly6C Expression after Renal Ischemia-Reperfusion Identifies Unique Macrophage Populations
M Clements, M Gershenovich, C Chaber, J Campos-Rivera, P Du, M Zhang, S Ledbetter, A Zuk
Journal of the American Society of Nephrology : JASN 2015
Inflammation in AKI: Current Understanding, Key Questions, and Knowledge Gaps
H Rabb, MD Griffin, DB McKay, S Swaminathan, P Pickkers, MH Rosner, JA Kellum, C Ronco
Journal of the American Society of Nephrology : JASN 2015
The ABO Histo-Blood Group and AKI in Critically Ill Patients with Trauma or Sepsis
JP Reilly, BJ Anderson, NS Mangalmurti, TD Nguyen, DN Holena, Q Wu, ET Nguyen, MP Reilly, PN Lanken, JD Christie, NJ Meyer, MG Shashaty
Clinical journal of the American Society of Nephrology : CJASN 2015
Associations of Deceased Donor Kidney Injury With Kidney Discard and Function After Transplantation: Deceased Donor AKI
IE Hall, B Schröppel, MD Doshi, J Ficek, FL Weng, RD Hasz, H Thiessen-Philbrook, PP Reese, CR Parikh
American Journal of Transplantation 2015
WNT Agonist Decreases Tissue Damage and Improves Renal Function After Ischemia-Reperfusion:
M Kuncewitch, WL Yang, L Corbo, A Khader, J Nicastro, GF Coppa, P Wang
Shock 2015
Kidney Injury Molecule-1 Protects against Gα12 Activation and Tissue Damage in Renal Ischemia-Reperfusion Injury
O Ismail, X Zhang, J Wei, A Haig, BM Denker, RS Suri, A Sener, L Gunaratnam
2015
Vascular and circulating microRNAs in renal ischaemia-reperfusion injury: Vascular and circulating microRNAs in acute kidney injury
JM Lorenzen
The Journal of Physiology 2015
Cyclic Nucleotide Signalling in Kidney Fibrosis
E Schinner, V Wetzl, J Schlossmann
International journal of molecular sciences 2015
P2X7 receptor inhibition protects against ischemic acute kidney injury in mice
Y Yan, J Bai, X Zhou, J Tang, C Jiang, E Tolbert, G Bayliss, R Gong, TC Zhao, S Zhuang
American journal of physiology. Cell physiology 2015
Zebrafish Renal Pathology: Emerging Models of Acute Kidney Injury
RA McKee, RA Wingert
Current Pathobiology Reports 2015
Zebrafish Models of Kidney Damage and Repair
MC Cirio, MP de Caestecker, NA Hukriede
Current Pathobiology Reports 2015
Antithrombin nanoparticles improve kidney reperfusion and protect kidney function after ischemia-reperfusion injury
J Chen, C Vemuri, RU Palekar, JP Gaut, M Goette, L Hu, G Cui, H Zhang, SA Wickline
American journal of physiology. Renal physiology 2015
Activators of G Protein Signaling in the Kidney
F Park
The Journal of pharmacology and experimental therapeutics 2015
Effects of phosphodiesterase-5 inhibitor on ischemic kidney injury during nephron sparing surgery: quantitative assessment by NGAL and KIM-1
Y Lahoud, O Hussein, A Shalabi, O Nativ, H Awad, M Khamaisi, I Matar, O Nativ, Z Abassi
World Journal of Urology 2015
Shock Duration after Resuscitation Is Associated with Occurrence of Post-Cardiac Arrest Acute Kidney Injury
YW Kim, KC Cha, YS Cha, OH Kim, WJ Jung, TH Kim, BK Han, H Kim, KH Lee, E Choi, SO Hwang
Journal of Korean Medical Science 2015
Knockdown of augmenter of liver regeneration in HK-2 cells inhibits inflammation response via the mitogen-activated protein kinase signaling pathway
R Yan, L Zhang, N Xia, Q Liu, H Sun, H Guo
Inflammation Research 2015
Research Progress on Regulatory T Cells in Acute Kidney Injury
Y Wang, Y Tao
Journal of Immunology Research 2015
Microglia-Induced Maladaptive Plasticity Can Be Modulated by Neuropeptides In Vivo
S Morara, AM Colangelo, L Provini
Neural plasticity 2015
Epigenetics in acute kidney injury:
J Tang, S Zhuang
Current Opinion in Nephrology and Hypertension 2015
A Pilot Study Identifying a Set of microRNAs As Precise Diagnostic Biomarkers of Acute Kidney Injury
E Aguado-Fraile, E Ramos, E Conde, M Rodríguez, L Martín-Gómez, A Lietor, Á Candela, B Ponte, F Liaño, ML García-Bermejo, G Camussi
PloS one 2015
The cytohesin guanosine exchange factors (GEFs) are required to promote HGF‐mediated renal recovery after acute kidney injury (AKI) in mice
MM Reviriego‐Mendoza, LC Santy
Physiological Reports 2015
Urinary mitochondrial DNA is a biomarker of mitochondrial disruption and renal dysfunction in acute kidney injury
RM Whitaker, LJ Stallons, JE Kneff, JL Alge, JL Harmon, JJ Rahn, JM Arthur, CC Beeson, SL Chan, RG Schnellmann
Kidney International 2015
Low Systemic Oxygen Delivery and BP and Risk of Progression of Early AKI
M Raimundo, S Crichton, Y Syed, JR Martin, R Beale, D Treacher, M Ostermann
Clinical journal of the American Society of Nephrology : CJASN 2015
The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide
J Dalli, BD Kraft, RA Colas, M Shinohara, LE Fredenburgh, DR Hess, N Chiang, K Welty-Wolf, AM Choi, CA Piantadosi, CN Serhan
American journal of respiratory cell and molecular biology 2015
Myeloid Cell HO-ming in AKI
GR Kinsey
Journal of the American Society of Nephrology : JASN 2015
Pathophysiological role of different tubular epithelial cell death modes in acute kidney injury
SM Sancho-Martínez, JM López-Novoa, FJ López-Hernández
Clinical Kidney Journal 2015
Glycogen synthase kinase-3 inhibition attenuates fibroblast activation and development of fibrosis following renal ischemia-reperfusion in mice
SP Singh, S Tao, TA Fields, S Webb, RC Harris, R Rao
Disease models & mechanisms 2015
Heterogeneity of epigenetic changes at ischemia/reperfusion- and endotoxin-induced acute kidney injury genes
D Mar, SA Gharib, RA Zager, A Johnson, O Denisenko, K Bomsztyk
Kidney International 2015
Epigenetic regulation in acute kidney injury: new light in a dark area
C Tang, Z Dong
Kidney International 2015
Pigment Epithelium-Derived Factor Induces Endothelial Barrier Dysfunction via p38/MAPK Phosphorylation
T He, L Zhao, D Zhang, Q Zhang, J Jia, J Hu, Y Huang
BioMed Research International 2015
Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 Antibody
F Victorino, DK Sojka, KS Brodsky, EN McNamee, JC Masterson, D Homann, WM Yokoyama, HK Eltzschig, ET Clambey
Journal of immunology (Baltimore, Md. : 1950) 2015
Relationship between acute kidney injury before thoracic endovascular aneurysm repair and in-hospital outcomes in patients with type B acute aortic dissection
Hong-Mei Ren, Xiao Wang, Chun-Yan Hu, Bin Que, Hui Ai, Chun-Mei Wang, Li-Zhong Sun, Shao-Ping Nie
Journal of Geriatric Cardiology 2015
Renal Hemodynamics in AKI: In Search of New Treatment Targets
M Matejovic, C Ince, LS Chawla, R Blantz, BA Molitoris, MH Rosner, MD Okusa, JA Kellum, C Ronco
Journal of the American Society of Nephrology : JASN 2015
An RNA interference screen identifies new avenues for nephroprotection
ER Zynda, B Schott, S Gruener, E Wernher, GD Nguyen, M Ebeling, ES Kandel
Cell Death and Differentiation 2015
Association Between the Neutrophil/Lymphocyte Ratio and Acute Kidney Injury After Cardiovascular Surgery: A Retrospective Observational Study
WH Kim, JY Park, SH Ok, IW Shin, JT Sohn
Medicine 2015
Cell adhesion molecule control of planar spindle orientation
H Tuncay, K Ebnet
Cellular and Molecular Life Sciences 2015
Advancing Cardiovascular, Neurovascular, and Renal Magnetic Resonance Imaging in Small Rodents Using Cryogenic Radiofrequency Coil Technology
T Niendorf, A Pohlmann, HM Reimann, H Waiczies, E Peper, T Huelnhagen, E Seeliger, A Schreiber, R Kettritz, K Strobel, MC Ku, S Waiczies
Frontiers in pharmacology 2015
Wnt/β-catenin signaling in kidney injury and repair: a double-edged sword
D Zhou, RJ Tan, H Fu, Y Liu
Laboratory Investigation 2015
Sulfenic Acid Modification of Endothelin B Receptor is Responsible for the Benefit of a Nonsteroidal Mineralocorticoid Receptor Antagonist in Renal Ischemia
J Barrera-Chimal, S Prince, F Fadel, SE Moghrabi, DG Warnock, P Kolkhof, F Jaisser
Journal of the American Society of Nephrology : JASN 2015
Autophagy Induces Prosenescent Changes in Proximal Tubular S3 Segments
A Baisantry, S Bhayana, S Rong, E Ermeling, C Wrede, J Hegermann, P Pennekamp, I So rensen-Zender, H Haller, A Melk, R Schmitt
Journal of the American Society of Nephrology : JASN 2015
Cyclic helix B peptide inhibits ischemia reperfusion-induced renal fibrosis via the PI3K/Akt/FoxO3a pathway
C Yang, Y Cao, Y Zhang, L Li, M Xu, Y Long, R Rong, T Zhu
Journal of Translational Medicine 2015
Evaluation of the role of the cannabidiol system in an animal model of ischemia/reperfusion kidney injury
RZ Soares, F Vuolo, DM DallIgna, M Michels, JA de Crippa, JE Hallak, AW Zuardi, F Dal-Pizzol
Revista Brasileira de Terapia Intensiva 2015
A Friend in Need: Activated Protein C Stabilizes YB-1 during Renal Ischemia Reperfusion Injury
B Griffin, M Murphy
Journal of the American Society of Nephrology : JASN 2015
Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545
Z Abassi, S Hamoud, A Hassan, I Khamaysi, O Nativ, SN Heyman, RS Muhammad, N Ilan, P Singh, E Hammond, G Zaza, A Lupo, M Onisto, G Bellin, V Masola, I Vlodavsky, G Gambaro
Oncotarget 2015
Cell-Specific Translational Profiling in Acute Kidney Injury
Jing Liu, Michaela Krautzberger, Shannan Sui, Oliver Hoffman, Ying Chen, Manfred Baetscher, Ivica Grgic, Sanjeev Kumar, Benjamin D. Humphreys, Winston Hide, Andrew McMahon
Journal of Clinical Investigation 2014
Therapeutic Translation in Acute Kidney Injury: The Epithelial-Endothelial Axis
Bruce A Molitoris
Journal of Clinical Investigation 2014
Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney
MR Ebrahimkhani, A Daneshmand, A Mazumder, M Allocca, JA Calvo, N Abolhassani, I Jhun, S Muthupalani, C Ayata, LD Samson
Proceedings of the National Academy of Sciences 2014
MicroRNA-24 Antagonism Prevents Renal Ischemia Reperfusion Injury
JM Lorenzen, T Kaucsar, C Schauerte, R Schmitt, S Rong, A Hübner, K Scherf, J Fiedler, F Martino, R Kumarswamy, M Kölling, I Sörensen, H Hinz, J Heineke, E Rooij, H Haller, T Thum
Journal of the American Society of Nephrology : JASN 2014
Vascular-Resident CD169-Positive Monocytes and Macrophages Control Neutrophil Accumulation in the Kidney with Ischemia-Reperfusion Injury
K Karasawa, K Asano, S Moriyama, M Ushiki, M Monya, M Iida, E Kuboki, H Yagita, K Uchida, K Nitta, M Tanaka
Journal of the American Society of Nephrology : JASN 2014
Changes in Metabolic Profiles during Acute Kidney Injury and Recovery following Ischemia/Reperfusion
Q Wei, X Xiao, P Fogle, Z Dong
PloS one 2014
The role of complement in the pathogenesis of renal ischemia-reperfusion injury and fibrosis
JS Danobeitia, A Djamali, LA Fernandez
Fibrogenesis & Tissue Repair 2014
Upregulation of Stromal Cell–Derived Factor 1 (SDF-1) is Associated with Macrophage Infiltration in Renal Ischemia-Reperfusion Injury
X Wan, W Xia, Y Gendoo, W Chen, W Sun, D Sun, C Cao, M Wang
2014
The role of sphingosine-1-phosphate in endothelial barrier function
BA Wilkerson, KM Argraves
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2014
Sphingosine 1-Phosphate Receptor-1 Enhances Mitochondrial Function and Reduces Cisplatin-Induced Tubule Injury
A Bajwa, DL Rosin, P Chroscicki, S Lee, K Dondeti, H Ye, GR Kinsey, BK Stevens, K Jobin, BM Kenwood, KL Hoehn, KR Lynch, MD Okusa
Journal of the American Society of Nephrology : JASN 2014
Expanding role of T cells in acute kidney injury
GR Kinsey, MD Okusa
Current Opinion in Nephrology and Hypertension 2014
Immune system modulation of kidney regeneration—mechanisms and implications
HJ Anders
Nature Reviews Nephrology 2014
In Vivo Clonal Analysis Reveals Lineage-Restricted Progenitor Characteristics in Mammalian Kidney Development, Maintenance, and Regeneration
Y Rinkevich, DT Montoro, H Contreras-Trujillo, O Harari-Steinberg, AM Newman, JM Tsai, X Lim, R Van-Amerongen, A Bowman, M Januszyk, O Pleniceanu, R Nusse, MT Longaker, IL Weissman, B Dekel
Cell Reports 2014
Regulated Cell Death in AKI
A Linkermann, G Chen, G Dong, U Kunzendorf, S Krautwald, Z Dong
Journal of the American Society of Nephrology : JASN 2014
Hematopoietic MicroRNA-126 Protects against Renal Ischemia/Reperfusion Injury by Promoting Vascular Integrity
R Bijkerk, C Solingen, HC de Boer, P der Pol, M Khairoun, RG de Bruin, AM van Oeveren-Rietdijk, E Lievers, N Schlagwein, DJ van Gijlswijk, MK Roeten, Z Neshati, AA de Vries, M Rodijk, K Pike-Overzet, YW van Berg, EP van der Veer, HH Versteeg, ME Reinders, FJ Staal, C Kooten, TJ Rabelink, AJ van Zonneveld
Journal of the American Society of Nephrology : JASN 2014
Tubular p53 Regulates Multiple Genes to Mediate AKI
D Zhang, Y Liu, Q Wei, Y Huo, K Liu, F Liu, Z Dong
Journal of the American Society of Nephrology : JASN 2014
Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury
G Canaud, JV Bonventre
Nephrology Dialysis Transplantation 2014
Urinary TIMP-2 and IGFBP7 as Early Biomarkers of Acute Kidney Injury and Renal Recovery following Cardiac Surgery
M Meersch, C Schmidt, HV Aken, S Martens, J Rossaint, K Singbartl, D Görlich, JA Kellum, A Zarbock, P Rosenberger
PloS one 2014
Kidney Regeneration in Mammals
HC Yang, SJ Liu, AB Fogo
Nephron Experimental Nephrology 2014
Who regenerates the kidney tubule?
R Kramann, T Kusaba, BD Humphreys
Nephrology Dialysis Transplantation 2014
Toll-Like Receptor 4-Induced IL-22 Accelerates Kidney Regeneration
OP Kulkarni, I Hartter, SR Mulay, J Hagemann, MN Darisipudi, SK Vr, S Romoli, D Thomasova, M Ryu, S Kobold, HJ Anders
Journal of the American Society of Nephrology : JASN 2014
Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury
K Moreth, H Frey, M Hubo, J Zeng-Brouwers, MV Nastase, LT Hsieh, R Haceni, J Pfeilschifter, RV Iozzo, L Schaefer
Matrix Biology 2014
Acute kidney injury: what part do toll-like receptors play?
PG Vallés, AG Lorenzo, V Bocanegra, R Vallés
International journal of nephrology and renovascular disease 2014
A Tissue-Specific Role for Nlrp3 in Tubular Epithelial Repair after Renal Ischemia/Reperfusion
PJ Bakker, LM Butter, N Claessen, GJ Teske, FS Sutterwala, S Florquin, JC Leemans
The American Journal of Pathology 2014
Defining the Acute Kidney Injury and Repair Transcriptome
S Kumar, J Liu, AP McMahon
Seminars in Nephrology 2014
Renal atrophy after ischemia–reperfusion injury depends on massive tubular apoptosis induced by TNFα in the later phase
T Adachi, N Sugiyama, H Yagita, T Yokoyama
Medical Molecular Morphology 2014
Renalase Prevents AKI Independent of Amine Oxidase Activity
L Wang, H Velazquez, G Moeckel, J Chang, A Ham, HT Lee, R Safirstein, GV Desir
Journal of the American Society of Nephrology : JASN 2014
First evidence of subclinical renal tubular injury during sickle-cell crisis
V Audard, S Moutereau, G Vandemelebrouck, A Habibi, M Khellaf, P Grimbert, Y Levy, S Loric, B Renaud, P Lang, B Godeau, F Galactéros, P Bartolucci
Orphanet Journal of Rare Diseases 2014
Serum-stabilized Naked Caspase-3 siRNA Protects Autotransplant Kidneys in a Porcine Model
C Yang, T Zhao, Z Zhao, Y Jia, L Li, Y Zhang, M Song, R Rong, M Xu, ML Nicholson, T Zhu, B Yang
Molecular Therapy 2014
Characterization of Kidney Injury Molecule-1 in Cats
SK Bland, O Côté, ME Clark, J DeLay, D Bienzle
Journal of Veterinary Internal Medicine 2014
Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis
R Gandhi, J Yi, J Ha, H Shi, O Ismail, S Nathoo, JV Bonventre, X Zhang, L Gunaratnam
American journal of physiology. Renal physiology 2014
The regulation of inflammatory mediators in acute kidney injury via exogenous mesenchymal stem cells
T Du, YJ Zhu
Mediators of Inflammation 2014
Biology of Renal Recovery: Molecules, Mechanisms, and Pathways
IS Vincent, MD Okusa
Nephron Clinical Practice 2014
DNA damage response in renal ischemia–reperfusion and ATP-depletion injury of renal tubular cells
Z Ma, Q Wei, G Dong, Y Huo, Z Dong
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2014
OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury
X Xiao, Y Hu, PM Quiros, Q Wei, C Lopez-Otin, Z Dong
American journal of physiology. Renal physiology 2014
Modulation of early inflammatory response by different balanced and non-balanced colloids and crystalloids in a rodent model of endotoxemia
S Voigtsberger, M Urner, M Hasler, BR Z'graggen, C Booy, DR Spahn, B Beck-Schimmer
PloS one 2014
Endothelial dysfunction and renal fibrosis in endotoxemia-induced oliguric kidney injury: possible role of LPS-binding protein
G Castellano, A Stasi, A Intini, M Gigante, AD Palma, C Divella, G Netti, C Prattichizzo, P Pontrelli, A Crovace, F Staffieri, E Fiaccadori, N Brienza, G Grandaliano, G Pertosa, L Gesualdo
Critical Care 2014
IL-22 Ameliorates Renal Ischemia-Reperfusion Injury by Targeting Proximal Tubule Epithelium
MJ Xu, D Feng, H Wang, Y Guan, X Yan, B Gao
Journal of the American Society of Nephrology : JASN 2014
New tides: using zebrafish to study renal regeneration
KK McCampbell, RA Wingert
Translational Research 2014
Administration of BMSCs with Muscone in Rats with Gentamicin-Induced AKI Improves Their Therapeutic Efficacy
P Liu, Y Feng, C Dong, D Yang, B Li, X Chen, Z Zhang, Y Wang, Y Zhou, L Zhao
PloS one 2014
Slit2-Robo signaling in inflammation and kidney injury
S Chaturvedi, LA Robinson
Pediatric Nephrology 2014
Id proteins regulate capillary repair and perivascular cell proliferation following ischemia-reperfusion injury
D Lee, S Shenoy, Y Nigatu, M Plotkin
PloS one 2014
A Unified Theory of Sepsis-Induced Acute Kidney Injury: Inflammation, Microcirculatory Dysfunction, Bioenergetics, and the Tubular Cell Adaptation to Injury
H Gomez, C Ince, DD Backer, P Pickkers, D Payen, J Hotchkiss, JA Kellum
Shock 2014
Cell cycle-dependent chromatin shuttling of HBO1–JADE1 histone acetyl transferase (HAT) complex
NS Siriwardana, R Meyer, A Havasi, I Dominguez, MV Panchenko
Cell cycle (Georgetown, Tex.) 2014
Autophagy in Acute Kidney Injury
MJ Livingston, Z Dong
Seminars in Nephrology 2014
Absence of chloride intracellular channel 4 (CLIC4) predisposes to acute kidney injury but has minimal impact on recovery
JC Edwards, J Bruno, P Key, YW Cheng
BMC Nephrology 2014
Stigmata of death: for kidneys and patients
C Ronco, JV Bonventre
Nephrology Dialysis Transplantation 2014
NGS Nominated CELA1, HSPG2, and KCNK5 as Candidate Genes for Predisposition to Balkan Endemic Nephropathy
D Toncheva, M Mihailova-Hristova, R Vazharova, R Staneva, S Karachanak, P Dimitrov, V Simeonov, S Ivanov, L Balabanski, D Serbezov, M Malinov, V Stefanovic, R Cukuranović, M Polenakovic, L Jankovic-Velickovic, V Djordjevic, T Jevtovic-Stoimenov, D Plaseska-Karanfilska, A Galabov, V Djonov, I Dimova
BioMed Research International 2014
LPS-induced delayed preconditioning is mediated by Hsp90 and involves the heat shock response in mouse kidney
T Kaucsár, C Bodor, M Godó, C Szalay, C Révész, Z Németh, M Mózes, G Szénási, L Rosivall, C Sőti, P Hamar
PloS one 2014
T1-mapping for assessment of ischemia-induced acute kidney injury and prediction of chronic kidney disease in mice
K Hueper, M Peperhove, S Rong, J Gerstenberg, M Mengel, M Meier, M Gutberlet, S Tewes, A Barrmeyer, R Chen, H Haller, F Wacker, D Hartung, F Gueler
European Radiology 2014
Angiotensin II Removes Kidney Resistance Conferred by Ischemic Preconditioning
HS Jang, JI Kim, J Kim, JW Park, KM Park
BioMed Research International 2014
Correlation between the cytology of urine sediment in fresh sample and smears stained by Papanicolaou and Giemsa methods
LA Palaoro, M Angerosa
Journal of Cytology / Indian Academy of Cytologists 2014
Basement Membrane Zone Collagens XV and XVIII/Proteoglycans Mediate Leukocyte Influx in Renal Ischemia/Reperfusion
A Zaferani, DT Talsma, S Yazdani, JW Celie, M Aikio, R Heljasvaara, GJ Navis, T Pihlajaniemi, J Born
PloS one 2014
Tannic acid label indicates abnormal cell development coinciding with regeneration of renal tubules
WW Minuth, L Denk
BMC clinical pathology 2014
Positive effects of a novel non-peptidyl low molecular weight radical scavenger in renal ischemia/reperfusion: a preliminary report
R Bassi, A Vergani, F D’Addio, MB Nasr, A Mocci, MP Rastaldi, T Ichimura, JV Bonventre, P Fiorina
SpringerPlus 2014
RGS4 inhibits angiotensin II signaling and macrophage localization during renal reperfusion injury independent of vasospasm
P Pang, X Jin, BM Proctor, M Farley, N Roy, MS Chin, UH von Andrian, E Vollmann, M Perro, RJ Hoffman, J Chung, N Chauhan, M Mistri, AJ Muslin, JV Bonventre, AM Siedlecki
Kidney International 2014
Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury
J Huang, D Wan, J Li, H Chen, K Huang, L Zheng
Epigenetics : official journal of the DNA Methylation Society 2014
Cystatin C for early detection of acute kidney injury after laparoscopic partial nephrectomy
Y Caumartin, T Dujardin, L Lacombe, G Nadeau, A Alesawi, A Bergeron
Urology annals 2014
Validation of Cell-Cycle Arrest Biomarkers for Acute Kidney Injury after Pediatric Cardiac Surgery
M Meersch, C Schmidt, HV Aken, J Rossaint, D Görlich, D Stege, E Malec, K Januszewska, A Zarbock, D Ma
PloS one 2014
Catheter-based induction of renal ischemia/reperfusion in swine: description of an experimental model
PA Malagrino, G Venturini, PS Yogi, R Dariolli, K Padilha, B Kiers, TC Gois, JM da Motta-Leal-Filho, CK Takimura, AC Girardi, FC Carnevale, AC Zeri, DM Malheiros, JE Krieger, AC Pereira
Physiological Reports 2014
G-Protein    Subunit Dimers Modulate Kidney Repair after Ischemia-Reperfusion Injury in Rats
SM White, LM North, E Haines, M Goldberg, LM Sullivan, JD Pressly, DS Weber, F Park, KR Regner
Molecular pharmacology 2014
Severe Renal Mass Reduction Impairs Recovery and Promotes Fibrosis after AKI
AJ Polichnowski, R Lan, H Geng, KA Griffin, MA Venkatachalam, AK Bidani
Journal of the American Society of Nephrology : JASN 2014
Development of an Immunoassay for the Kidney-Specific Protein myo-Inositol Oxygenase, a Potential Biomarker of Acute Kidney Injury
JP Gaut, DL Crimmins, MF Ohlendorf, CM Lockwood, TA Griest, NA Brada, M Hoshi, B Sato, RS Hotchkiss, S Jain, JH Ladenson
Clinical chemistry 2014
Syncytial communication in descending vasa recta includes myoendothelial coupling
Z Zhang, K Payne, TL Pallone
American journal of physiology. Renal physiology 2014
Remote conditioning or erythropoietin before surgery primes kidneys to clear ischemia-reperfusion-damaged cells: a renoprotective mechanism?
DS Gardner, SJ Welham, LJ Dunford, TA McCulloch, Z Hodi, P Sleeman, S O'Sullivan, MA Devonald
American journal of physiology. Renal physiology 2014
Epac-Rap Signaling Reduces Oxidative Stress in the Tubular Epithelium
G Stokman, Y Qin, TH Booij, S Ramaiahgari, M Lacombe, ME Dolman, KM van Dorenmalen, GJ Teske, S Florquin, F Schwede, B de Water, RJ Kok, LS Price
Journal of the American Society of Nephrology : JASN 2014
Downregulation of cystathionine  -synthase and cystathionine  -lyase expression stimulates inflammation in kidney ischemia-reperfusion injury
P Wang, CK Isaak, YL Siow, K O
Physiological Reports 2014
Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney
KK McCampbell, KN Springer, RA Wingert
Journal of visualized experiments : JoVE 2014
Anti-fibrotic vitamin D analogues
Joseph V. Bonventre
Journal of Clinical Investigation 2013
Tolerance of the human kidney to isolated controlled ischemia
DJ Parekh, JM Weinberg, B Ercole, KC Torkko, W Hilton, M Bennett, P Devarajan, MA Venkatachalam
Journal of the American Society of Nephrology : JASN 2013
Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology
M Zhan, C Brooks, F Liu, L Sun, Z Dong
Kidney International 2013
Sustained Activation of EGFR Triggers Renal Fibrogenesis after Acute Kidney Injury
J Tang, N Liu, E Tolbert, M Ponnusamy, L Ma, R Gong, G Bayliss, H Yan, S Zhuang
The American Journal of Pathology 2013
The Role of the Complement System in Acute Kidney Injury
JW McCullough, B Renner, JM Thurman
Seminars in Nephrology 2013
Preventive Effects of a Natural Anti-Inflammatory Agent, Astragaloside IV, on Ischemic Acute Kidney Injury in Rats
S Tan, G Wang, Y Guo, D Gui, N Wang
Evidence-Based Complementary and Alternative Medicine 2013
Moving beyond supportive care—current status of specific therapies in pediatric acute kidney injury
JM Symons
Pediatric Nephrology 2013
Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule-specific knockout mouse models
Q Wei, G Dong, JK Chen, G Ramesh, Z Dong
Kidney international. Supplement 2013
The immune system and kidney disease: basic concepts and clinical implications
C Kurts, U Panzer, HJ Anders, AJ Rees
Nature Reviews Immunology 2013
Regenerative medicine for the kidney: stem cell prospects & challenges
Y Li, RA Wingert
Clinical and Translational Medicine 2013
Met Activation Is Required for Early Cytoprotection after Ischemic Kidney Injury
S Mason, C Hader, A Marlier, G Moeckel, LG Cantley
Journal of the American Society of Nephrology : JASN 2013
Stem cells: potential and challenges for kidney repair
M Herrera, M Mirotsou
American journal of physiology. Renal physiology 2013
Blockade of Death Ligand TRAIL Inhibits Renal Ischemia Reperfusion Injury
T Adachi, N Sugiyama, T Gondai, H Yagita, T Yokoyama
ACTA HISTOCHEMICA ET CYTOCHEMICA 2013
Stromal cells in tissue homeostasis: balancing regeneration and fibrosis
TJ Rabelink, MH Little
Nature Reviews Nephrology 2013
Controversies on the origin of proliferating epithelial cells after kidney injury
T Kusaba, BD Humphreys
Pediatric Nephrology 2013
Sisters in arms: myeloid and tubular epithelial cells shape renal innate immunity
T Hato, TM El-Achkar, PC Dagher
American journal of physiology. Renal physiology 2013
Innate versus adaptive immunity in kidney immunopathology
HJ Anders
BMC Nephrology 2013
Macrophage Phenotype Controls Long-Term AKI Outcomes--Kidney Regeneration versus Atrophy
M Lech, R Gröbmayr, M Ryu, G Lorenz, I Hartter, SR Mulay, HE Susanti, KS Kobayashi, RA Flavell, HJ Anders
Journal of the American Society of Nephrology : JASN 2013
Omega-3 fatty acid-derived resolvins and protectins in inflammation resolution and leukocyte functions: targeting novel lipid mediator pathways in mitigation of acute kidney injury
S Hong, Y Lu
Frontiers in immunology 2013
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Hypoxia Induces Mesenchymal Gene Expression in Renal Tubular Epithelial Cells: An in vitro Model of Kidney Transplant Fibrosis
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Histone deacetylase inhibitor enhances recovery after AKI
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Journal of the American Society of Nephrology : JASN 2013
Ultrasound prevents renal ischemia-reperfusion injury by stimulating the splenic cholinergic anti-inflammatory pathway
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Journal of the American Society of Nephrology : JASN 2013
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Expert Opinion on Drug Metabolism & Toxicology 2013
Genetic deficiency of adiponectin protects against acute kidney injury
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Kidney International 2013
Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1α activation following ischemia–reperfusion injury
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Toxicology and Applied Pharmacology 2013
Extracellular membrane vesicles from umbilical cord blood-derived MSC protect against ischemic acute kidney injury, a feature that is lost after inflammatory conditioning
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Journal of Extracellular Vesicles 2013
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury
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Critical Care 2013
Epigenetic Alterations in Acute Kidney Injury
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Seminars in Nephrology 2013
Regulatory T Cells in AKI
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Journal of the American Society of Nephrology : JASN 2013
Nanosized Contrast Agents to Noninvasively Detect Kidney Inflammation by Magnetic Resonance Imaging
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Advances in Chronic Kidney Disease 2013
Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease
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Kidney International 2013
'Biologic memory' in response to acute kidney injury: cytoresistance, toll-like receptor hyper-responsiveness and the onset of progressive renal disease
RA Zager
Nephrology Dialysis Transplantation 2013
Comparison of absolute serum creatinine changes versus Kidney Disease: Improving Global Outcomes consensus definitions for characterizing stages of acute kidney injury
HE Wang, G Jain, RJ Glassock, DG Warnock
Nephrology Dialysis Transplantation 2013
Histone Acetyl Transferase (HAT) HBO1 and JADE1 in Epithelial Cell Regeneration
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The American Journal of Pathology 2013
Differentiated kidney epithelial cells repair injured proximal tubule
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Proceedings of the National Academy of Sciences 2013
High temporal resolution parametric MRI monitoring of the initial ischemia/reperfusion phase in experimental acute kidney injury
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PloS one 2013
A novel experimental model of orthopedic trauma with acute kidney injury in obese Zucker rats
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Physiological Reports 2013
Congenital and Acute Kidney Disease: Translational Research Insights from Zebrafish Chemical Genetics
SJ Poureetezadi, RA Wingert
2013
Endothelium injury and inflammatory state during abdominal aortic aneurysm surgery: scrutinizing the very early and minute injurious effects using endothelial markers - a pilot study
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Archives of Medical Science : AMS 2013
The impact of vascular anastomosis time on early kidney transplant outcomes
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Transplantation Research 2013
Quantitative renal perfusion measurements in a rat model of acute kidney injury at 3T: testing inter- and intramethodical significance of ASL and DCE-MRI
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American journal of physiology. Cell physiology 2013
Renal Cells from Spermatogonial Germline Stem Cells Protect against Kidney Injury
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Journal of the American Society of Nephrology : JASN 2013
Proximal Tubule Proliferation Is Insufficient to Induce Rapid Cyst Formation after Cilia Disruption
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Journal of the American Society of Nephrology : JASN 2013
Histological Study on Effect of Mesenchymal Stem Cell Therapy on Experimental Renal Injury Induced by Ischemia/Reperfusion in Male Albino Rat
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International journal of stem cells 2013
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Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in mice
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Dendritic Cell Sphingosine 1-Phosphate Receptor-3 Regulates Th1–Th2 Polarity in Kidney Ischemia–Reperfusion Injury
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Journal of immunology (Baltimore, Md. : 1950) 2012
Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis
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Journal of Innate Immunity 2012
Adora2b adenosine receptor signaling protects during acute kidney injury via inhibition of neutrophil-dependent TNF-α release
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Journal of immunology (Baltimore, Md. : 1950) 2012
Podocytes Express IL-6 and Lipocalin 2/ Neutrophil Gelatinase-Associated Lipocalin in Lipopolysaccharide-Induced Acute Glomerular Injury
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Heterozygosity for fibrinogen results in efficient resolution of kidney ischemia reperfusion injury
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p53 is renoprotective after ischemic kidney injury by reducing inflammation
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Autophagy in proximal tubules protects against acute kidney injury
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American journal of physiology. Renal physiology 2012
Dying cells and extracellular histones in AKI: beyond a NET effect?
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AMPK activator AICAR ameliorates ischaemia reperfusion injury in the rat kidney
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British Journal of Pharmacology 2012
miR-127 Protects Proximal Tubule Cells against Ischemia/Reperfusion: Identification of Kinesin Family Member 3B as miR-127 Target
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PloS one 2012
EGFR activity is required for renal tubular cell dedifferentiation and proliferation in a murine model of folic acid-induced acute kidney injury
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American journal of physiology. Renal physiology 2012
Transcriptome analysis of renal ischemia/reperfusion injury and its modulation by ischemic pre-conditioning or hemin treatment
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PloS one 2012
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