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Citations to this article

Myasthenia gravis: past, present, and future
Bianca M. Conti-Fine, … , Monica Milani, Henry J. Kaminski
Bianca M. Conti-Fine, … , Monica Milani, Henry J. Kaminski
Published November 1, 2006
Citation Information: J Clin Invest. 2006;116(11):2843-2854. https://doi.org/10.1172/JCI29894.
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Myasthenia gravis: past, present, and future

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Abstract

Myasthenia gravis (MG) is an autoimmune syndrome caused by the failure of neuromuscular transmission, which results from the binding of autoantibodies to proteins involved in signaling at the neuromuscular junction (NMJ). These proteins include the nicotinic AChR or, less frequently, a muscle-specific tyrosine kinase (MuSK) involved in AChR clustering. Much is known about the mechanisms that maintain self tolerance and modulate anti-AChR Ab synthesis, AChR clustering, and AChR function as well as those that cause neuromuscular transmission failure upon Ab binding. This insight has led to the development of improved diagnostic methods and to the design of specific immunosuppressive or immunomodulatory treatments.

Authors

Bianca M. Conti-Fine, Monica Milani, Henry J. Kaminski

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Consistent improvement with eculizumab across muscle groups in myasthenia gravis
R Mantegazza, FL O'Brien, M Yountz, JF Howard, CG Mazia, M Wilken, F Barroso, J Saba, M Rugiero, M Bettini, M Chaves, G Vidal, AD Garcia, JD Bleecker, GV den Abeele, K de Koning, KD Mey, R Mercelis, D Mahieu, L Wagemaekers, PV Damme, A Depreitere, C Schotte, C Smetcoren, O Stevens, SV Daele, N Vandenbussche, A Vanhee, S Verjans, J Vynckier, A DHont, P Tilkin, AA de Siqueira Carvalho, ID Brockhausen, D Feder, D Ambrosio, P César, AP Melo, RM Ribeiro, R Rocha, BB Rosa, T Veiga, LA da Silva, MS Engel, JG Geraldo, M da Penha Ananias Morita, EN Coelho, G Paiva, M Pozo, N Prando, DD Torres, CF Butinhao, G Duran, TA Fialho, TC da Silva, LO Gonçalves, LE Pazetto, LR Volpe, LS Duca, MA Friedrich, A Guerreiro, H Mohr, MP Martins, D da Cruz Pacheco, L Ferreira, AP Macagnan, G Pinto, A de Cassia Santos, AS Oliveira, AC de Andrade, M Annes, LD Silva, VC Lino, W Pinto, N Assis, F Carrara, C Miranda, I Souza, P Fernandes, Z Siddiqi, C Phan, J Narayan, D Blackmore, A Mallon, R Roderus, E Watt, S Vohanka, J Bednarik, M Chmelikova, M Cierny, S Toncrova, J Junkerova, B Kurkova, K Reguliova, O Zapletalova, J Pitha, I Novakova, M Tyblova, I Jurajdova, M Wolfova, H Andersen, T Harbo, L Vinge, S Krogh, A Mogensen, J Vissing, J Højgaard, N Witting, AM Autzen, J Pedersen, JP Erälinna, M Laaksonen, O Oksaranta, T Harrison, J Eriksson, C Rozsa, M Horvath, G Lovas, J Matolcsi, G Szabo, G Jakab, B Szabadosne, L Vecsei, L Dezsi, E Varga, M Konyane, G Antonini, AD Pasquale, M Garibaldi, S Morino, F Troili, L Fionda, A Pasquale, A Evoli, PE Alboini, V DAmato, R Iorio, M Inghilleri, L Fionda, V Frasca, E Giacomelli, M Gori, D Lopergolo, E Onesti, V Frasca, M Gabriele, F Saccà, A Filla, T Costabile, E Marano, A Fasanaro, A Marsili, G Puorro, C Antozzi, S Bonanno, G Camera, A Locatelli, L Maggi, M Pasanisi, A Campanella, A Uzawa, T Kanai, N Kawaguchi, M Mori, Y Kaneko, A Kanzaki, E Kobayashi, H Murai, K Masaki, D Matsuse, T Matsushita, T Uehara, M Shimpo, M Jingu, K Kikutake, Y Nakamura, Y Sano, K Utsugisawa, Y Nagane, I Kamegamori, T Tsuda, Y Fujii, K Futono, Y Ozawa, A Mizugami, Y Saito, M Samukawa, H Suzuki, M Morikawa, S Kamakura, E Miyawaki, M Okumura, S Funaka, T Kawamura, M Nakamori, M Takahashi, N Taichi, T Hasuike, E Higuchi, H Kobayashi, K Osakada, H Shiraishi, T Miyazaki, M Motomura, A Mukaino, S Yoshimura, S Asada, S Yoshida, S Amamoto, T Kobashikawa, M Koga, Y Maeda, K Takada, M Takada, M Tsurumaru, Y Yamashita, Y Suzuki, T Akiyama, K Narikawa, O Tano, K Tsukita, R Kurihara, F Meguro, Y Fukuda, M Sato, T Imai, E Tsuda, S Shimohama, T Hayashi, S Hisahara, T Imai, J Kawamata, T Murahara, M Saitoh, S Shimohama, S Suzuki, D Yamamoto, Y Ishiyama, N Ishiyama, M Noshiro, R Takeyama, K Uwasa, I Yasuda, A van der Kooi, M de Visser, T Gibson, BJ Kim, CN Lee, YS Koo, HY Seok, HN Kang, HJ Ra, BJ Kim, EB Cho, MS Choi, HL Lee, JH Min, J Seok, JE Lee, DY Koh, JY Kwon, SA Park, EH Choi, YH Hong, SH Ahn, DL Koo, JS Lim, CW Shin, JY Hwang, M Kim, SM Kim, HN Jeong, JW Jung, Y Kim, HS Lee, HY Shin, EB Hwang, M Shin, C Casasnovas, MA Aguilo, C HomedesPedret, NJ Palacios, LD Porras, VV Santamaria, A Lazaro, JG Carbonell, P Sune, MS Figueras, G Gili, G Mazuela, I Illa, EC Vicente, J DiazManera, LA Gutiérrez, RR Garcia, N Vidal, E ArribasIbar, ED Tejedor, PG Salcedo, M FernandezFournier, PL Ruiz, FJ de Rivera, M FernandezFournier, M Sastre, F Piehl, A Hietala, L Bjarbo, I Sengun, A Meherremova, P Ozcelik, B Balkan, C Tuga, M Ugur, S ErdemOzdamar, CE BekircanKurt, NP Acar, E Yilmaz, Y Caliskan, G Orsel, H Efendi, S Aydinlik, H Cavus, A Kutlu, G Becerikli, C Semiz, O Tun, M Terzi, B Dogan, MK Onar, S Sen, TK Cavdar, A Veske, F Norwood, A Dimitriou, J Gollogly, M MahdiRogers, A Seddigh, G Sokratous, G Maier, F Sohail, S Jacob, G Sadalage, P Torane, C Brown, A Shah, S Sathasivam, H Arndt, D Davies, D Watling, A Amato, T Cochrane, M Salajegheh, K Roe, K Amato, S Toska, G Wolfe, N Silvestri, K Patrick, K Zakalik, J Katz, R Miller, M Engel, D Forshew, E Bravver, B Brooks, M Sanjak, S Plevka, M Burdette, S Cunningham, M Kramer, J Nemeth, C Schommer, T Scott, V Juel, J Guptill, L HobsonWebb, J Massey, K Beck, D Carnes, J Loor, A Anderson, R Pascuzzi, C Bodkin, J Kincaid, R Snook, S Guingrich, A Micheels, V Chaudhry, A Corse, B Mosmiller, A Kelley, D Ho, J Srinivasan, M Vytopil, J Jara, N Ventura, C Carter, C Donahue, C Herbert, S Scala, E Weiner, S Alam, J McKinnon, L Haar, N McKinnon, K Alcon, K McKenna, N Sattar, K Daniels, D Jeffery, M Freimer, JC Hoyle, J Kissel, J Agriesti, S Chelnick, L Mezache, C Pineda, F Muharrem, C Karam, J Khoury, T Marburger, H Kaur, D Dimitrova, J Gilchrist, B Agrawal, M Elsayed, S Kohlrus, A Ardoin, T Darnell, L Golden, B Lokaitis, J Seelbach, S Muppidi, N Goyal, S Sakamuri, YT So, S Paulose, S Pol, L Welsh, R BhavarajuSanka, AT Gonzalez, L Dishman, F Jones, A Gonzalez, P Padilla, A Saklad, M Silva, S Nations, J Trivedi, S Hopkins, M Kazamel, M Alsharabati, L Lu, K Nozaki, S MumfreyThomas, A Woodall, T Mozaffar, T Cash, N Goyal, G Roy, V Mathew, F Maqsood, B Minton, HJ Jones, J Rosenfeld, R Garcia, L Echevarria, S Garcia, M Pulley, S Aranke, AR Berger, J Shah, Y Shabbir, L Smith, M Varghese, Y Shabbir, L Gutmann, L Gutmann, N Jerath, C Nance, A Swenson, H Olalde, N Kressin, J Sieren, R Barohn, M Dimachkie, M Glenn, A McVey, M Pasnoor, J Statland, Y Wang, T Liu, K Emmons, N Jenci, J Locheke, A Fondaw, K Johns, G Rico, M Walsh, L Herbelin, C HaferMacko, J Kwan, L Zilliox, K Callison, V Young, B DiSanzo, K Naunton, M Benatar, M Bilsker, K Sharma, A Cooley, E Reyes, SC Michon, D Sheldon, J Steele, C Karam, R Traub, M Chopra, T Vu, L Katzin, T McClain, B Harvey, A Hart, K Huynh, S Beydoun, A Chilingaryan, V Doan, B Droker, H Gong, S Karimi, F Lin, T McClain, K Polaka, A Shah, A Tran, S Akhter, A Malekniazi, R Tandan, M Hehir, W Waheed, S Lucy, M Weiss, J Distad, S Strom, S Downing, B Kim, T Bertorini, T Arnold, K Henderson, R Pillai, Y Liu, L Wheeler, J Hewlett, M Vanderhook, R Nowak, D Dicapua, B Keung, A Kumar, H Patwa, K Robeson, I Yang, J Nye, H Vu
Annals of Clinical and Translational Neurology 2020
Inhibition of the transcription factor ROR-γ reduces pathogenic Th17 cells in acetylcholine receptor antibody positive myasthenia gravis
JS Yi, MA Russo, S Raja, JM Massey, VC Juel, J Shin, LD Hobson-Webb, K Gable, JT Guptill
Experimental Neurology 2020
Clinical features of LRP4 /agrin‐antibody–positive myasthenia gravis: A multicenter study
MH Rivner, BM Quarles, JX Pan, Z Yu, JF Howard, A Corse, MM Dimachkie, C Jackson, T Vu, G Small, RP Lisak, J Belsh, I Lee, RJ Nowak, V Baute, S Scelsa, JA Fernandes, Z Simmons, A Swenson, R Barohn, RB Sanka, C Gooch, E Ubogu, J Caress, M Pasnoor, H Xu, L Mei
Muscle & Nerve 2020
Review Analysis on Thymectomy vs Conservative Medical Management in Myasthenia Gravis
Rashid MH, Yasir HK, Piracha MU, Salman U, Yousaf H
Cureus 2020
Concomitant Immunosuppressive Therapy Use in Eculizumab-Treated Adults With Generalized Myasthenia Gravis During the REGAIN Open-Label Extension Study
Nowak RJ, Muppidi S, Beydoun SR, O'Brien FL, Yountz M, Howard JF Jr
Frontiers in neurology 2020
History of Myasthenia Gravis Revisited
Deymeer F
2020
The Purinergic System as a Pharmacological Target for the Treatment of Immune-Mediated Inflammatory Diseases
L Antonioli, C Blandizzi, P Pacher, G Haskó, C Page
Pharmacological reviews 2019
Role of complement and potential of complement inhibitors in myasthenia gravis and neuromyelitis optica spectrum disorders: a brief review
JL Chamberlain, S Huda, DH Whittam, M Matiello, BP Morgan, A Jacob
Journal of Neurology 2019
Development of a dual-functional conjugate of antigenic peptide and Fc-III mimetics (DCAF) for targeted antibody blocking
L Zhang, H Shen, Y Gong, X Pang, M Yi, L Guo, J Li, S Arroyo, X Lu, S Ovchinnikov, G Cheng, X Liu, X Jiang, S Feng, H Deng
Chemical Science 2019
Immunosuppressive and monoclonal antibody treatment for myasthenia gravis: A network meta-analysis
L Wang, X Huan, , H Wu, L Zhou, JH Lu, TS Zhang, CB Zhao
CNS Neuroscience & Therapeutics 2019
The ancient sarcomeric myosins found in specialized muscles
LA Lee, A Karabina, LJ Broadwell, LA Leinwand
Skeletal Muscle 2019
Long-term safety and efficacy of eculizumab in generalized myasthenia gravis: Long-Term Eculizumab in gMG
S Muppidi, K Utsugisawa, M Benatar, H Murai, RJ Barohn, I Illa, S Jacob, J Vissing, TM Burns, JT Kissel, RJ Nowak, H Andersen, C Casasnovas, JL de Bleecker, TH Vu, R Mantegazza, FL O'Brien, JJ Wang, KP Fujita, JF Howard
Muscle & Nerve 2019
Eculizumab improves fatigue in refractory generalized myasthenia gravis
H Andersen, R Mantegazza, JJ Wang, F OBrien, K Patra, JF Howard
Quality of Life Research 2019
Impact of Refractory Myasthenia Gravis on Health-Related Quality of Life:
AN Boscoe, H Xin, GJ LʼItalien, LA Harris, GR Cutter
Journal of Clinical Neuromuscular Disease 2019
Examining the Impact of Refractory Myasthenia Gravis on Healthcare Resource Utilization in the United States: Analysis of a Myasthenia Gravis Foundation of America Patient Registry Sample
H Xin, LA Harris, IB Aban, G Cutter
Journal of clinical neurology (Seoul, Korea) 2019
Concurrence of Myasthenia Gravis and Thyroid Disorders: A Retrospective Database Study
Virameteekul S, Charoensri S, Sawanyawisuth K, Tiamkao S
2019
Engineered agrin attenuates the severity of experimental autoimmune myasthenia gravis: Engineered Agrin Attenuates EAMG
Z Li, M Li, K Wood, S Hettwer, SA Muley, FD Shi, Q Liu, SS Ladha
Muscle & Nerve 2018
Cannabinoid-induced increase of quantal size and enhanced neuromuscular transmission
M Morsch, DA Protti, D Cheng, F Braet, RS Chung, SW Reddel, WD Phillips
Scientific Reports 2018
When myasthenia gravis is deemed refractory: clinical signposts and treatment strategies
R Mantegazza, C Antozzi
Therapeutic advances in neurological disorders 2018
Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis
C Galdeano, N Coquelle, M Cieslikiewicz-Bouet, M Bartolini, B Pérez, M Clos, I Silman, L Jean, JP Colletier, PY Renard, D Muñoz-Torrero
Molecules (Basel, Switzerland) 2018
Advances in autoimmune myasthenia gravis management
S Wang, I Breskovska, S Gandhy, AR Punga, JT Guptill, HJ Kaminski
Expert Review of Neurotherapeutics 2018
Thymectomy in nonthymomatous myasthenia gravis - systematic review and meta-analysis
AJ Cataneo, G Felisberto, DC Cataneo
Orphanet Journal of Rare Diseases 2018
General anesthesia using supraglottic airway device in a myasthenic patient undergoing reverse shoulder arthroplasty
SS Kamath, JC Misquith
Anesthesia: Essays and Researches 2018
Unexpected dislocation following accurate total hip arthroplasty caused by excessive hip joint laxity during myasthenic crisis: a case report
Y Murotani, Y Kuroda, K Goto, T Kawai, S Matsuda
Journal of medical case reports 2018
Modified Buzhong Yiqi decoction for myasthenia gravis: A systematic review protocol
X Jiang, G Chen, J Huang, L Xie, D Shen, K Jiang, H Xu
Medicine 2018
Mechanisms of Autoantibody-Induced Pathology
RJ Ludwig, K Vanhoorelbeke, F Leypoldt, Z Kaya, K Bieber, SM McLachlan, L Komorowski, J Luo, O Cabral-Marques, CM Hammers, JM Lindstrom, P Lamprecht, A Fischer, G Riemekasten, C Tersteeg, P Sondermann, B Rapoport, KP Wandinger, C Probst, AE Beidaq, E Schmidt, A Verkman, RA Manz, F Nimmerjahn
Frontiers in immunology 2017
Autoimmune Thyroiditis and Myasthenia Gravis
A Lopomo, S Berrih-Aknin
Frontiers in Endocrinology 2017
Response to: Comment on “Detecting Key Genes Regulated by miRNAs in Dysfunctional Crosstalk Pathway of Myasthenia Gravis”
Y Cao, J Wang, H Zhang, Q Tian, L Chen, S Ning, P Liu, X Sun, X Lu, C Song, S Zhang, B Xiao, L Wang
BioMed Research International 2017
Suppression of CHRN endocytosis by carbonic anhydrase CAR3 in the pathogenesis of myasthenia gravis
A Du, S Huang, X Zhao, K Feng, S Zhang, J Huang, X Miao, F Baggi, RS Ostrom, Y Zhang, X Chen, C Xu
Autophagy 2017
The potential role of cell surface complement regulators and circulating CD4+ CD25+ T-cells in the development of autoimmune myasthenia gravis
MN Hamdoon, M Fattouh, AN El-din, HM Elnady
Electronic Physician 2016
Concomitant presentation of Anderson-Tawil syndrome and myasthenia gravis in an adult patient: A case report
R Fan, R Ji, W Zou, G Wang, H Wang, D Penney, J Luo, Y Fan
Experimental and therapeutic medicine 2016
Animal models of myasthenia gravis: utility and limitations
R Mantegazza, C Cordiglieri, A Consonni, F Baggi
International journal of general medicine 2016
Follicular Helper T (Tfh) Cells in Autoimmune Diseases and Allograft Rejection
YH Jeon, YS Choi
Immune Network 2016
Neuromuscular junctions are pathological but not denervated in two mouse models of spinal bulbar muscular atrophy
JE Poort, MB Rheuben, SM Breedlove, CL Jordan
Human Molecular Genetics 2016
Clustering drug-drug interaction networks with energy model layouts: community analysis and drug repurposing
L Udrescu, L Sbârcea, A Topîrceanu, A Iovanovici, L Kurunczi, P Bogdan, M Udrescu
Scientific Reports 2016
Seropositivity for West Nile Virus Antibodies in Patients Affected by Myasthenia Gravis
M Greco, P Cofano, G Lobreglio
Journal of clinical medicine research 2016
Effect of therapeutic plasma exchange on immunoglobulins in myasthenia gravis
JT Guptill, VC Juel, JM Massey, AC Anderson, M Chopra, JS Yi, E Esfandiari, T Buchanan, B Smith, P Atherfold, E Jones, JF Howard
Autoimmunity 2016
Double Seronegative Myasthenia Gravis with Anti-LRP4 Antibodies Presenting with Dropped Head and Acute Respiratory Insufficiency
G Beck, T Yabumoto, K Baba, T Sasaki, O Higuchi, H Matsuo, H Mochizuki
Internal Medicine 2016
A Novel Fusion Protein, AChR-Fc, Ameliorates Myasthenia Gravis by Neutralizing Antiacetylcholine Receptor Antibodies and Suppressing Acetylcholine Receptor-Reactive B Cells
M Homma, A Uzawa, H Tanaka, N Kawaguchi, T Kanai, K Nakajima, M Narita, Y Hara, H Maruyama, Y Ogawa, K Himuro, S Kuwabara
Neurotherapeutics 2016
Effect of Gender, Disease Duration and Treatment on Muscle Strength in Myasthenia Gravis
G Citirak, S Cejvanovic, H Andersen, J Vissing, AV Gomes
PloS one 2016
Refractory myasthenia gravis - clinical profile, comorbidities and response to rituximab
Sreenivasa Rao Sudulagunta, Mona Sepehrar, Mahesh Babu Sodalagunta, Aravinda Settikere Nataraju, Shiva Kumar Bangalore Raja, Deepak Sathyanarayana, Siddharth Gummadi, Hemanth Kumar Burra
GMS German Medical Science 2016
Animal Models for the Study of Neuroimmunological Disease
Croxford JL, Miyake S
Neuroimmunological Diseases 2016
Validation of the MG-DIS: a disability assessment for myasthenia gravis.
Raggi A, Leonardi M, Schiavolin S, Antozzi C, Brenna G, Maggi L, Mantegazza R
Journal of Neurology 2016
Guidelines for pre-clinical assessment of the acetylcholine receptor-specific passive transfer myasthenia gravis model—Recommendations for methods and experimental designs
LL Kusner, M Losen, A Vincent, J Lindstrom, S Tzartos, K Lazaridis, P Martinez-Martinez
Experimental Neurology 2015
Clinical Features of Autoimmune Autonomic Ganglionopathy and the Detection of Subunit-Specific Autoantibodies to the Ganglionic Acetylcholine Receptor in Japanese Patients
S Nakane, O Higuchi, M Koga, T Kanda, K Murata, T Suzuki, H Kurono, M Kunimoto, K Kaida, A Mukaino, W Sakai, Y Maeda, H Matsuo, G Saruhan-Direskeneli
PloS one 2015
Deficits in Endogenous Adenosine Formation by Ecto-5′-Nucleotidase/CD73 Impair Neuromuscular Transmission and Immune Competence in Experimental Autoimmune Myasthenia Gravis
L Oliveira, A Correia, AC Costa, S Guerra-Gomes, F Ferreirinha, MT Magalhães-Cardoso, M Vilanova, P Correia-de-Sá
Mediators of Inflammation 2015
Detecting Key Genes Regulated by miRNAs in Dysfunctional Crosstalk Pathway of Myasthenia Gravis
Y Cao, J Wang, H Zhang, Q Tian, L Chen, S Ning, P Liu, X Sun, X Lu, C Song, S Zhang, B Xiao, L Wang
BioMed Research International 2015
A Double-Blinded, Randomized, Placebo-Controlled Trial to Evaluate Efficacy, Safety, and Tolerability of Single Doses of Tirasemtiv in Patients with Acetylcholine Receptor-Binding Antibody-Positive Myasthenia Gravis
DB Sanders, J Rosenfeld, MM Dimachkie, L Meng, FI Malik
Neurotherapeutics 2015
A Challenging Diagnosis of Fluctuating Dyspnea: Myasthenia Gravis
R Mandaliya
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH 2015
Paravertebral Block Combined with Sedation for a Myasthenic Patient Undergoing Breast Augmentation
B Kozanhan, B Basaran, L Kutlucan, S Ozmen
Case Reports in Anesthesiology 2015
Myeloid-Derived Suppressor Cells as a Potential Therapy for Experimental Autoimmune Myasthenia Gravis
Y Li, Z Tu, S Qian, JJ Fung, SD Markowitz, LL Kusner, HJ Kaminski, L Lu, F Lin
Journal of immunology (Baltimore, Md. : 1950) 2014
Targeting therapy to the neuromuscular junction: Proof of concept: Targeted Therapy for MG
LL Kusner, N Satija, G Cheng, HJ Kaminski
Muscle & Nerve 2014
RNA Expression Analysis of Passive Transfer Myasthenia Supports Extraocular Muscle as a Unique Immunological Environment
Y Zhou, HJ Kaminski, B Gong, G Cheng, JM Feuerman, L Kusner
Investigative ophthalmology & visual science 2014
Effects of the ß2-adrenoceptor agonist, albuterol, in a mouse model of anti-MuSK myasthenia gravis
N Ghazanfari, M Morsch, N Tse, SW Reddel, WD Phillips
PloS one 2014
Stable expression of human muscle-specific kinase in HEp-2 M4 cells for automatic immunofluorescence diagnostics of myasthenia gravis
S George, S Paulick, I Knütter, N Röber, R Hiemann, D Roggenbuck, K Conrad, JH Küpper
PloS one 2014
Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis
M Thiruppathi, JR Sheng, L Li, BS Prabhakar, MN Meriggioli
Journal of Autoimmunity 2014
Analysis of Serum miRNA Profiles of Myasthenia Gravis Patients
G Nogales-Gadea, A Ramos-Fransi, X Suárez-Calvet, M Navas, R Rojas-García, JL Mosquera, J Díaz-Manera, L Querol, E Gallardo, I Illa
PloS one 2014
Double seronegative myasthenia gravis with antiphospholipid syndrome: a case report
D Dan, PA Bart, J Novy, T Kuntzer, C Clair
Journal of medical case reports 2014
Localized Thymic Amyloidosis Presenting with Myasthenia Gravis: Case Report
SM Son, YM Lee, SW Kim, OJ Lee
Journal of Korean Medical Science 2014
Whole-Genome Analysis in Korean Patients with Autoimmune Myasthenia Gravis
SJ Na, JH Lee, SW Kim, DS Kim, EH Shon, HJ Park, HY Shin, SM Kim, YC Choi
Yonsei Medical Journal 2014
Neuromodulation by acetylcholine: examples from schizophrenia and depression
MJ Higley, MR Picciotto
Current Opinion in Neurobiology 2014
Myasthenia gravis-like syndrome presenting as a component of the paraneoplastic syndrome of lung adenocarcinoma in a nonsmoker
S Eivaz-Mohammadi, F Gonzalez-Ibarra, H Hekmatjou, R Mikkilineni, A Patel, AK Syed
Case Reports in Oncological Medicine 2014
Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model study
LL Kusner, MJ Ciesielski, A Marx, HJ Kaminski, RA Fenstermaker
PloS one 2014
Is Dosing of Therapeutic Immunoglobulins Optimal? A Review of a Three-Decade Long Debate in Europe
J Kerr, I Quinti, M Eibl, H Chapel, PJ Späth, WA Sewell, A Salama, IN van Schaik, TW Kuijpers, HH Peter
Frontiers in immunology 2014
Intravenous immunoglobulin for preparing myasthenia gravis patients for thymectomy and other surgical procedures preventing myasthenic crisis: IVIg therapy in myasthenia gravis
J Gamez
Clinical & Experimental Immunology 2014
Tirasemtiv amplifies skeletal muscle response to nerve activation in humans: Tirasemtiv in Humans
R Hansen, KG Saikali, W Chou, AJ Russell, MM Chen, V Vijayakumar, RR Stoltz, S Baudry, RM Enoka, DJ Morgans, AA Wolff, FI Malik
Muscle & Nerve 2014
Ocular myasthenia gravis: A review
P Patil-Chhablani, DV Venkatramani, RA Gandhi, AG Nair
Indian journal of ophthalmology 2014
Direct Proof of the In Vivo Pathogenic Role of the AChR Autoantibodies from Myasthenia Gravis Patients
G Kordas, G Lagoumintzis, S Sideris, K Poulas, SJ Tzartos, W Phillips
PloS one 2014
DBC1 Is a Suppressor of B Cell Activation by Negatively Regulating Alternative NF- B Transcriptional Activity
S Kong, M Thiruppathi, Q Qiu, Z Lin, H Dong, EN Chini, BS Prabhakar, D Fang
Journal of immunology (Baltimore, Md. : 1950) 2014
Antigen-Specific Immunotherapeutic Vaccine for Experimental Autoimmune Myasthenia Gravis
J Luo, J Lindstrom
Journal of immunology (Baltimore, Md. : 1950) 2014
Acetylcholinesterase inhibitor treatment for myasthenia gravis
Mehndiratta MM, Pandey S, Kuntzer T
The Cochrane Database of Systematic Reviews 2014
Myasthenia gravis: analysis of serum autoantibody reactivities to 1827 potential human autoantigens by protein macroarrays
A Becker, N Ludwig, A Keller, B Tackenberg, C Eienbröker, WH Oertel, K Fassbender, E Meese, K Ruprecht
PloS one 2013
Induced Formation and Maturation of Acetylcholine Receptor Clusters in a Defined 3D Bio-Artificial Muscle
L Wang, J Shansky, H Vandenburgh
Molecular Neurobiology 2013
Improved methodology to obtain large quantities of correctly folded recombinant N-terminal extracellular domain of the human muscle acetylcholine receptor for inducing experimental autoimmune myasthenia gravis in rats
C Sun, H Zhang, J Xu, J Gao, X Qi, Z Li
Archives of Medical Science : AMS 2013
Pyridostigmine-induced high grade SA-block in a patient with myasthenia gravis
S Said, CJ Cooper, H Alkhateeb, S Elhanafi, J Bizet, S Gosavi, Z Abedin
American Journal of Case Reports 2013
Enhanced insight into the autoimmune component of glaucoma: IgG autoantibody accumulation and pro-inflammatory conditions in human glaucomatous retina
OW Gramlich, S Beck, NT Hohenstein-Blaul, N Boehm, A Ziegler, JM Vetter, N Pfeiffer, FH Grus
PloS one 2013
Serum IL-21 levels decrease with glucocorticoid treatment in myasthenia gravis.
Li Y, Rauniyar VK, Yin WF, Hu B, Ouyang S, Xiao B, Yang H
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2013
Environmental effects of anticholinesterasic therapeutic drugs on a crustacean species, Daphnia magna.
Rocha R, Gonçalves F, Marques C, Nunes B
Environmental Science and Pollution Research 2013
A Comparison of Epitope Repertoires Associated with Myasthenia Gravis in Humans and Nonhuman Hosts
K Vaughan, Y Kim, A Sette
Autoimmune Diseases 2012
Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases
AJ Russell, JJ Hartman, AC Hinken, AR Muci, R Kawas, L Driscoll, G Godinez, KH Lee, D Marquez, WF 4th, MM Chen, D Clarke, SE Collibee, M Garard, R Hansen, Z Jia, PP Lu, H Rodriguez, KG Saikali, J Schaletzky, V Vijayakumar, DL Albertus, DR Claflin, DJ Morgans, BP Morgan, FI Malik
Nature Medicine 2012
Fracture rate in patients with myasthenia gravis: the general practice research database
S Pouwels, A Boer, MK Javaid, D Hilton-Jones, J Verschuuren, C Cooper, HG Leufkens, F Vries
Osteoporosis International 2012
An undiagnosed myasthenia gravis presenting as isolated recurrent acute respiratory failure
SR Sharma, N Sharma, M Yeolekar
Journal of Neurosciences in Rural Practice 2012
Possible Involvement of Toll-Like Receptors in the Pathogenesis of Myasthenia Gravis
YZ Wang, M Yan, FF Tian, JM Zhang, Q Liu, H Yang, WB Zhou, J Li
Inflammation 2012
Prophylactic effect of probiotics on the development of experimental autoimmune myasthenia gravis
CS Chae, HK Kwon, JS Hwang, JE Kim, SH Im
PloS one 2012
Biomarker development for myasthenia gravis
HJ Kaminski, LL Kusner, GI Wolfe, I Aban, G Minisman, R Conwit, G Cutter
Annals of the New York Academy of Sciences 2012
Myasthenia gravis: a review
AJ Trouth, A Dabi, N Solieman, M Kurukumbi, J Kalyanam
Autoimmune Diseases 2012
Complement regulatory protein Crry deficiency contributes to the antigen specific recall response in experimental autoimmune myasthenia gravis
J Soltys, X Wu
Journal of Inflammation 2012
Chromatographic separation of reaction products from the choline acetyltransferase and carnitine acetyltransferase assay: differential ChAT and CrAT activity in brain extracts from Alzheimer's disease versus controls
JA Bailey, DK Lahiri
Journal of Neurochemistry 2012
Evaluation of a scale of patient-reported outcomes for the assessment of myasthenia gravis patients in China.
Liu FB, Chen XL, Guo L, Liu XB
Chinese Journal of Integrative Medicine 2012
Epidemiology of myasthenia gravis in Austria: rising prevalence in an ageing society.
Cetin H, Fülöp G, Zach H, Auff E, Zimprich F
Wiener klinische Wochenschrift 2012
Treatment for diplopia in patients with myasthenia gravis.
Park KA, Oh SY
2012
A case of Sheehan's syndrome that manifested as bilateral ptosis
YS Lee, SS Moon
Journal of Korean Medical Science 2011
Comparison of clinical manifestations between patients with ocular myasthenia gravis and generalized myasthenia gravis
HS Roh, SY Lee, JS Yoon
Korean journal of ophthalmology : KJO 2011
Myasthenogenicity of the main immunogenic region and endogenous muscle nicotinic acetylcholine receptors
J Luo, J Lindstrom
Autoimmunity 2011
Myasthenia Gravis: A Review of Available Treatment Approaches
NE Gilhus, JF Owe, JM Hoff, F Romi, GO Skeie, JA Aarli
Autoimmune Diseases 2011
The association of systemic lupus erythematosus and myasthenia gravis: a series of 17 cases, with a special focus on hydroxychloroquine use and a review of the literature
M Jallouli, D Saadoun, B Eymard, G Leroux, J Haroche, DT Huong, C Gennes, C Chapelon, O Benveniste, B Wechsler, P Cacoub, Z Amoura, JC Piette, N Costedoat-Chalumeau
Journal of Neurology 2011
Molecular control of neuromuscular junction development
E Ferraro, F Molinari, L Berghella
Journal of Cachexia, Sarcopenia and Muscle 2011
Anaesthetic management of a patient with myasthenia gravis for abdominal surgery using sugammadex
A Rudzka-Nowak, M Piechota
Archives of Medical Science : AMS 2011
Response of patients with refractory myasthenia gravis to rituximab: a retrospective study
RJ Nowak, DB Dicapua, N Zebardast, JM Goldstein
Therapeutic advances in neurological disorders 2011
Treatment of myasthenia gravis.
Kumar V, Kaminski HJ
Current Neurology and Neuroscience Reports 2011
Thymectomy for inducing remission in juvenile myasthenia gravis.
Hennessey IA, Long AM, Hughes I, Humphrey G
Pediatric Surgery International 2011
Elevated serum level of interleukin-32α in the patients with myasthenia gravis.
Na SJ, So SH, Lee KO, Choi YC
Journal of Neurology 2011
A retrospective review of 15 patients with familial myasthenia gravis over a period of 25 years.
Feng HY, Liu WB, Luo CM, Yang LX, Fang W, Qiu L, Huang X, Li Y, Huang RX
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2011
Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis
EG Hughes, X Peng, AJ Gleichman, M Lai, L Zhou, R Tsou, TD Parsons, DR Lynch, J Dalmau, RJ Balice-Gordon
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010
The neonatal Fc receptor as therapeutic target in IgG-mediated autoimmune diseases
A Sesarman, G Vidarsson, C Sitaru
Cellular and Molecular Life Sciences 2010
Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice: Actions of MuSK autoantibodies in experimental myasthenia gravis
RN Cole, N Ghazanfari, ST Ngo, OL Gervásio, SW Reddel, WD Phillips
The Journal of Physiology 2010
Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled alpha-subunits
C Valkova, M Albrizio, IV Röder, M Schwake, R Betto, R Rudolf, C Kaether
Proceedings of the National Academy of Sciences 2010
Long-acting anticholinesterases for myasthenia gravis: synthesis and activities of quaternary phenylcarbamates of neostigmine, pyridostigmine and physostigmine
QS Yu, HW Holloway, W Luo, DK Lahiri, A Brossi, NH Greig
Bioorganic & Medicinal Chemistry 2010
Extracorporeal immunoglobulin elimination for the treatment of severe myasthenia gravis
M Blaha, J Pit'ha, V Blaha, M Lanska, J Maly, S Filip, H Langrova
Journal of biomedicine & biotechnology 2010
Myasthenia gravis presenting as isolated respiratory failure: a case report
WH Kim, JH Kim, EK Kim, SP Yun, KK Kim, WC Kim, HC Jeong
The Korean Journal of Internal Medicine 2010
Social support and self-efficacy in patients with Myasthenia Gravis: a common pathway towards positive health outcomes.
Raggi A, Leonardi M, Mantegazza R, Casale S, Fioravanti G
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Acetylcholine receptor-α subunit expression in myasthenia gravis: A role for the autoantigen in pathogenesis?
JR Sheng, LC Li, BS Prabhakar, MN Meriggioli
Muscle & Nerve 2009
Novel complement inhibitor limits severity of experimentally myasthenia gravis
J Soltys, LL Kusner, A Young, C Richmonds, D Hatala, B Gong, V Shanmugavel, HJ Kaminski
Annals of Neurology 2009
Specific immunotherapy of experimental myasthenia gravis by a novel mechanism
J Luo, A Kuryatov, JM Lindstrom
Annals of Neurology 2009
Novel information on the non-neuronal cholinergic system in orthopedics provides new possible treatment strategies for inflammatory and degenerative diseases
S Forsgren, H Alfredson, D Bjur, S Rantapää-Dahlqvist, O Norrgård, T Dalén, P Danielson
Orthopedic reviews 2009
Antigenic structure of the human muscle nicotinic acetylcholine receptor main immunogenic region
J Luo, J Lindstrom
Journal of molecular neuroscience : MN 2009
Prediction of acute multiple sclerosis relapses by transcription levels of peripheral blood cells
M Gurevich, T Tuller, U Rubinstein, R Or-Bach, A Achiron
BMC Medical Genomics 2009
An Altered Phenotype in a Conditional Knockout of Pitx2 in Extraocular Muscle
Y Zhou, G Cheng, L Dieter, TA Hjalt, FH Andrade, JS Stahl, HJ Kaminski
Investigative ophthalmology & visual science 2009
The relationship between health, disability and quality of life in myasthenia gravis: results from an Italian study.
Leonardi M, Raggi A, Antozzi C, Confalonieri P, Maggi L, Cornelio F, Mantegazza R
Journal of Neurology 2009
Concordance between severity of disease, disability and health-related quality of life in myasthenia gravis.
Raggi A, Leonardi M, Antozzi C, Confalonieri P, Maggi L, Cornelio F, Mantegazza R
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2009
Extraocular Muscle Susceptibility to Myasthenia Gravis
J Soltys, B Gong, HJ Kaminski, Y Zhou, LL Kusner
Annals of the New York Academy of Sciences 2008
Effect of complement and its regulation on myasthenia gravis pathogenesis
LL Kusner, HJ Kaminski, J Soltys
Expert Review of Clinical Immunology 2008
Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn
AR Mezo, KA McDonnell, CA Hehir, SC Low, VJ Palombella, JM Stattel, GD Kamphaus, C Fraley, Y Zhang, JA Dumont, AJ Bitonti
Proceedings of the National Academy of Sciences 2008
Autoantibodies in neuromuscular transmission disorders
A Vincent
Annals of Indian Academy of Neurology 2008
Elimination of Schistosoma mansoni Adult Worms by Rhesus Macaques: Basis for a Therapeutic Vaccine?
RA Wilson, JA Langermans, GJ van Dam, RA Vervenne, SL Hall, WC Borges, GP Dillon, AW Thomas, PS Coulson
PLoS neglected tropical diseases 2008
Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays
L Soreq, A Gilboa-Geffen, S Berrih-Aknin, P Lacoste, A Darvasi, E Soreq, H Bergman, H Soreq
PloS one 2008
Myasthenia gravis in a patient affected by glycogen storage disease type Ib: A further manifestation of an increased risk for autoimmune disorders?
D Melis, F Balivo, RD Casa, A Romano, R Taurisano, B Capaldo, G Riccardi, MR Monsurrò, G Parenti, G Andria
Journal of Inherited Metabolic Disease 2008
Discrimination between Host and Pathogens by the Complement System
Pangburn MK, Ferreira VP, Cortes C
Vaccine 2008

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