During active disease, patients with systemic-onset juvenile chronic arthritis (S-JCA) demonstrate a rise and fall in serum interleukin-6 (IL-6) that parallels the classic quotidian fever. To investigate the possibility that this cytokine profile results from a difference in the control of IL-6 expression, we examined the 5' flanking region of the IL-6 gene for polymorphisms. A G/C polymorphism was detected at position -174. In a group of 383 healthy men and women from a general practice in North London, the frequency of the C allele was 0.403 (95% confidence interval 0.37-0.44). In comparison, 92 patients with S-JCA had a different overall genotype frequency, especially those with onset of disease at < 5 yr of age. This was mainly due to the statistically significant lower frequency of the CC genotype in this subgroup. When comparing constructs of the 5' flanking region (-550-+61 bp) in a luciferase reporter vector transiently transfected into HeLa cells, the -174C construct showed 0.624+/-0.15-fold lower expression than the -174G construct. After stimulation with LPS or IL-1, expression from the -174C construct did not significantly change after 24 h, whereas expression from the -174G construct increased by 2.35+/-0.10- and 3.60+/-0.26-fold, respectively, compared with the unstimulated level. Plasma levels of IL-6 were also measured in 102 of the healthy subjects, and the C allele was found to be associated with significantly lower levels of plasma IL-6. These results suggest that there is a genetically determined difference in the degree of the IL-6 response to stressful stimuli between individuals. The reduced frequency of the potentially protective CC genotype in young S-JCA patients may contribute to its pathogenesis. Similarly the individual's IL-6 genotype may be highly relevant in other conditions where IL-6 has been implicated, such as atherosclerosis.
D Fishman, G Faulds, R Jeffery, V Mohamed-Ali, J S Yudkin, S Humphries, P Woo
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Polymorphisms of Interleukin-6 and Interleukin-8 Are Not Associated with Parkinson’s Disease in Taiwan
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Pharmacogenomics and Personalized Medicine | 2021 |
Association of Genetic Polymorphisms and Serum Levels of IL-6 and IL-8 with the Prognosis in Children with Neuroblastoma
SS Moreno-Guerrero, A Ramírez-Pacheco, LM Rocha-Ramírez, G Hernández-Pliego, P Eguía-Aguilar, MA Escobar-Sánchez, A Reyes-López, LE Juárez-Villegas, JJ Sienra-Monge |
Cancers | 2021 |
Current and emerging biological therapy in adult-onset Still’s disease
Y Ma, J Meng, J Jia, M Wang, J Teng, D Zhu, C Yang, Q Hu |
Rheumatology | 2021 |
Acute Pancreatitis: Genetic Risk and Clinical Implications
FU Weiss, F Laemmerhirt, MM Lerch |
Journal of Clinical Medicine | 2021 |
Association of recipient and donor interleukin 6 polymorphisms 174 and 597 with outcome after allogeneic hematopoietic stem cell transplantation in children
L Wetzel, S Wittig, B Gruhn |
Journal of Cancer Research and Clinical Oncology | 2021 |
Risk of Recurrent Pregnancy Loss in the Ukrainian Population Using a Combined Effect of Genetic Variants: A Case-Control Study.
Loizidou EM, Kucherenko A, Tatarskyy P, Chernushyn S, Livshyts G, Gulkovskyi R, Vorobiova I, Antipkin Y, Gorodna O, Kaakinen MA, Prokopenko I, Livshits L |
Genes & development | 2021 |
Association of NFκβ, TNFα, IL-6, IL-1β, and LPL Polymorphisms with Type 2 Diabetes Mellitus and Biochemical Parameters in a Mexican Population.
Martínez-Ramírez OC, Salazar-Piña DA, de Lorena RM, Castro-Hernández C, Casas-Ávila L, Portillo-Jacobo JA, Rubio J |
Biochemical Genetics | 2021 |
Polymorphisms of Interleukin-6 and Interleukin-8 Are Not Associated with Parkinson's Disease in Taiwan.
Liu TW, Wu YR, Chen YC, Fung HC, Chen CM |
Brain Sciences | 2021 |
Association between IL-18 and IL-6 gene polymorphisms and the risk of T1D in Egyptian children.
Ali YBM, El-Gahel HE, Abdel-Hakem NE, Gadalla ME, El-Hefnawy MH, El-Shahat M |
2021 | |
Analysis of association between MALAT1 haplotype and the severity of normal-tension glaucoma (NTG).
Yue JL, Zheng SF |
Journal of Cellular and Molecular Medicine | 2021 |
Polymorphism of interleukin-6 -174 G/C (rs1800795) & the corresponding interleukin-6 level as a prognostic marker of cervical cancer.
Wagh P, Kulkarni P, Kerkar S, Tongaonkar H, Chaudhari H, Warke H, Deodhar K, Rekhi B, Mania-Pramanik J |
The Indian journal of medical research | 2021 |
Association between single nucleotide polymorphisms of IL-6 and susceptibility to skin cancer: a meta-analysis and systematic review.
Guo K, Lu Z, Wang X, Qiao J |
Translational cancer research | 2021 |
Genetic characteristics of competitive swimmers: a review.
Ben-Zaken S, Eliakim A, Nemet D, Kaufman L, Meckel Y |
Biology of Sport | 2021 |
Interactions of genetic variants and prenatal stress in relation to the risk for recurrent respiratory infections in children.
Korhonen LS, Lukkarinen M, Kantojärvi K, Räty P, Karlsson H, Paunio T, Peltola V, Karlsson L |
Scientific Reports | 2021 |
Interplay between IL6 and CRIM1 in thiopurine intolerance due to hematological toxicity in leukemic patients with wild-type NUDT15 and TPMT.
Kim H, You S, Park Y, Choi JY, Ma Y, Hong KT, Koh KN, Yun S, Lee KH, Shin HY, Lee S, Yoo KH, Im HJ, Kang HJ, Kim JH |
Scientific Reports | 2021 |
Analysis of transcriptomic data sets supports the role of IL-6 in NETosis and immunothrombosis in severe COVID-19.
Mukhopadhyay S, Sinha S, Mohapatra SK |
2021 | |
The Association of IL-6, TNFα and CRP Gene Polymorphisms with Coronary Artery Disease in a Tunisian Population: A Case-Control study.
Grira N, Lahidheb D, Lamine O, Ayoub M, Wassaifi S, Aouni Z, Fehri W, Mazigh C |
Biochemical Genetics | 2021 |
Interleukin 6 (rs1800795) and pentraxin 3 (rs2305619) polymorphisms-association with inflammation and all-cause mortality in end-stage-renal disease patients on dialysis.
Rocha S, Valente MJ, Coimbra S, Catarino C, Rocha-Pereira P, Oliveira JG, Madureira J, Fernandes JC, do Sameiro-Faria M, Miranda V, Belo L, Santos-Silva A, Bronze-da-Rocha E |
Scientific Reports | 2021 |
The polymorphisms of IL-6/STAT3 signaling pathway may contribute to cutaneous T-cell lymphomas susceptibility
B Olszewska, J Gleń, M Zabłotna, RJ Nowicki, M Sokołowska-Wojdyło |
Archives of Dermatological Research | 2020 |
IL-6 in inflammation, autoimmunity and cancer
T Hirano |
International Immunology | 2020 |
A Specific IL6 Polymorphic Genotype Modulates the Risk of Trypanosoma cruzi Parasitemia While IL18, IL17A, and IL1B Variant Profiles and HIV Infection Protect Against Cardiomyopathy in Chagas Disease
AG dos Santos, EH Watanabe, DT Ferreira, J Oliveira, ÉS Nakanishi, CS Oliveira, E Bocchi, CT Novaes, F Cruz, NB Carvalho, PK Sato, EH Yamashiro-Kanashiro, A Pontillo, VL de Freitas, LF Onuchic, MA Shikanai-Yasuda |
Frontiers in immunology | 2020 |
Interactions among Interleukin-6, C-Reactive Protein and Interleukin-6 (-174) G/C Polymorphism in the Pathogenesis of Crohn’s Disease and Ulcerative Colitis
B Takač |
ACTA CLIN CROAT | 2020 |
Interleukin-6 -174 G/C polymorphism is associated with the risk of basal cell carcinoma in a Chinese Han population
J Wang, Y Chen |
Aging | 2020 |
The Multi-Omics Architecture of Juvenile Idiopathic Arthritis
X Hou, H Qu, S Zhang, X Qi, H Hakonarson, Q Xia, J Li |
Cells | 2020 |
Interleukin-6-174G/C polymorphism is associated with a decreased risk of type 2 diabetes in patients with chronic hepatitis C virus
CB da Silva, DA Vieira, LF de Melo, AL Chagas, AD Gomes, , R Teixeira, DM de Magalhães Queiroz, GA Rocha, MM Soares, JM Bezerra, LD Silva |
World journal of hepatology | 2020 |
Tumor mutation burden associated with miRNA-gene interaction outcome mediates the survival of patients with liver hepatocellular carcinoma.
Yu QJ, Liang YZ, Mei XP, Fang TY |
EXCLI journal | 2020 |
Cancer Immunology: A Translational Medicine Context
N Rezaei |
2020 | |
How autoinflammation may turn into autoimmune inflammation: Insights from monogenetic and complex IL-1 mediated auto-inflammatory diseases
NM ter Haar, MH Jansen, JF Frenkel, SJ Vastert |
Clinical Immunology | 2020 |
The combined frequencies of the IL-6 G-174C and IGFBP3 A-202C polymorphisms among swimmers and runners
S Ben-Zaken, Y Meckel, D Nemet, E Kassem, A Eliakim |
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society | 2020 |
Molecular and Cellular Mechanisms of Arthritis in Children and Adults: New Perspectives on Applied Photobiomodulation
LM Ailioaie, G Litscher |
International journal of molecular sciences | 2020 |
IL6 and FAS/FASL gene polymorphisms may be associated with disease progression in HIV‐1‐positive ethnically mixed patients
MM dos Reis, MA Queiroz, BC Silva, AJ Duarte, J Casseb, GA Arganaraz, AC Vallinoto, ER Argañaraz |
Journal of Medical Virology | 2020 |
Investigation of the Role of Interleukin 6 in Vitiligo Pathogenesis
M Singh, SD Jadeja, J Vaishnav, MS Mansuri, C Shah, JM Mayatra, A Shah, R Begum |
Immunological Investigations | 2020 |
Interleukin Gene Variability and Periodontal Bacteria in Patients with Generalized Aggressive Form of Periodontitis
PB Linhartova, Z Danek, T Deissova, F Hromcik, B Lipovy, D Szaraz, J Janos, A Fassmann, J Bartova, I Drizhal, LI Holla |
International journal of molecular sciences | 2020 |
The Perfect Storm: COVID-19 Health Disparities in US Blacks
N Phillips, IW Park, JR Robinson, HP Jones |
Journal of Racial and Ethnic Health Disparities | 2020 |
The Association between Interleukin-6 Gene Polymorphisms and Risk of Systemic Lupus Erythematosus: A Meta-analysis with Trial Sequential Analysis
J Liu, MQ Liao, DF Cao, Y Yang, Y Yang, YH Liu, FF Zeng, XH Chen |
Immunological Investigations | 2020 |
Genetic polymorphisms in the Interleukins IL1B, IL4, and IL6 are associated with concomitant periodontitis and type 2 diabetes mellitus in Brazilian patients
T Cirelli, R Nepomuceno, AC Rios, SR Orrico, JA Cirelli, LH Theodoro, SP Barros, RM ScarelCaminaga |
Journal of Periodontal Research | 2020 |
Meta-analysis and field synopsis of genetic variants associated with the risk and severity of acute pancreatitis
FF van den Berg, MA Kempeneers, HC van Santvoort, AH Zwinderman, Y Issa, MA Boermeester |
2020 | |
Cytokine genes multi-locus analysis reveals synergistic influence on genetic susceptibility in Indian SLE – A multifactor-dimensionality reduction approach
V Umare, V Pradhan, S Dadheech, A Rajadhyaksha, K Ghosh, A Nadkarni |
Cytokine | 2020 |
Real-Time Monitoring and Detection of Single-Cell Level Cytokine Secretion Using LSPR Technology
C Zhu, , WV Espulgar, S Koyama, A Kumanogoh, M Saito, H Takamatsu, E Tamiya |
MICROMACHINES-BASEL | 2020 |
IL6 genetic variants haplotype is associated with susceptibility and disease activity but not with therapy response in patients with inflammatory bowel disease
BP Gonçalves, T Flauzino, CJ Inoue, JC de Paula, TC Galvão, CC de Alcantara, PK Miyazaki, L Rosa, S Westmore, MA Lozovoy, EM Reiche, AN Simão |
International Journal of Colorectal Disease | 2020 |
Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database
A Ceschi, R Noseda, K Palin, K Verhamme |
Frontiers in pharmacology | 2020 |
Genetic Polymorphisms in Transforming Growth Factor-β, Interferon-γ and Interleukin-6 Genes and Susceptibility to Behcet’s Disease in Saudi Population FA Okaily, S Alrashidi, M Mustafa, FB Alrashdan |
Pharmacogenomics and Personalized Medicine | 2020 |
Risk Factors for Recurrent Colorectal Polyps
Y Hao, Y Wang, M Qi, X He, Y Zhu, J Hong |
Gut and Liver | 2020 |
Systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome due to a CASP1 variant causing inflammasome hyperactivation
SE Jørgensen, M Christiansen, C Høst, M Glerup, B Mahler, MM Lausten, HH Gad, R Hartmann, T Herlin, TH Mogensen |
Rheumatology | 2020 |
Role of Interleukin-6 in Depressive Disorder
EY Ting, AC Yang, SJ Tsai |
International journal of molecular sciences | 2020 |
Association between interleukin gene polymorphisms and multiple myeloma susceptibility
M Shahzad, I Ijaz, S Naqvi, C Yan, F Lin, S Li, C Huang |
Molecular and Clinical Oncology | 2020 |
Association of CRP, CD14, Pro-Inflammatory Cytokines and Their Receptors (TNFA, LTA, TNFRSF1A, TNFRSF1B, IL1B, and IL6) Genes with Chronic Obstructive Pulmonary Disease Development
GF Korytina, LZ Akhmadishina, OV Kochetova, YG Aznabaeva, SM Izmailova, SZ Zagidullin, TV Victorova |
Russian Journal of Genetics | 2020 |
Impact of IL-17F 7488T/C Functional Polymorphism on Progressive Rheumatoid Arthritis: Novel Insight from the Molecular Dynamic Simulations
H Nisar, U Pasha, MU Mirza, R Abid, K Hanif, HN Kadarmideen, S Sadaf |
Immunological Investigations | 2020 |
Interactions Between Diet Quality and Interleukin-6 Genotypes Are Associated With Metabolic and Renal Function Parameters in Mexican Patients With Type 2 Diabetes Mellitus
EF Gómez-García, L Cortés-Sanabria, AM Cueto-Manzano, RS Medina-Zavala, LE Hernández-Ramos, HR Martínez-Ramírez, JC Vásquez-Jiménez, F Mendoza-Carrera |
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation | 2020 |
Epidemic Myalgia Associated with Human Parechovirus Type 3 Infection
M Miyazaki, K Hara, T Takayoshi, T Kawase, Y Nakagawa, T Arai, T Sugimoto, K Nishiyama, G Gonzalez, N Hanaoka, T Fujimoto, Y Yasutomo, K Yokono |
Internal Medicine | 2020 |
Association of IL-6 174G/C (rs1800795) and 572C/G (rs1800796) polymorphisms with risk of osteoporosis: a meta-analysis
B Chen, H Li |
BMC musculoskeletal disorders | 2020 |
Clinical Management of Il-6 Driven Cytokine Storm Related to COVID-19 in a Patient with Recent Spinal Cord Stimulator Implants: A Case Report
A Papa, MT Dato, P Buonavolonta, E Saracco, AM Salzano, B Casale |
Anesthesiology and Pain Medicine | 2020 |
Association of Polymorphisms in Cytokine genes with susceptibility to Precancerous Lesions and Cervical Cancer: A systematic review with meta-analysis
EL de Moura, AC dos Santos, DM da Silva, BB dos Santos, D de Siqueira Figueredo, AW Moura, AF da Silva, IS Tanabe, EL de Lira Tanabe, AB Neto, AC e Silva, CA de Carvalho Fraga, JL de Lima Filho, KF de Farias, EV de Souza |
Immunological Investigations | 2020 |
Role of inflammatory and pain genes polymorphisms in temporomandibular disorder and pressure pain sensitivity
LM Fiamengui, BD Furquim, GD la Torre Canales, FF Soares, RL Poluha, CE Repeke, LR Bonjardim, GP Garlet, PC Conti |
Archives of Oral Biology | 2020 |
Meta-analysis of association between il-6-174 g/c polymorphism and female infertility related disorders
JJ Benjamin, T Koshy, KM Kumar, KN Maruthy, R Padmavathi |
Journal of Reproductive Immunology | 2020 |
The role of IL-6-174 G/C polymorphism and intraocular IL-6 levels in the pathogenesis of ocular diseases: a systematic review and meta-analysis
ZS Ulhaq, GV Soraya, Budu, LR Wulandari |
Scientific Reports | 2020 |
IL-1β, IL-6, IL-10, and TNFα Single Nucleotide Polymorphisms in Human Influence the Susceptibility to Alzheimer’s Disease Pathology
MB Leko, MN Perković, N Klepac, DŠ Štrac, F Borovečki, N Pivac, PR Hof, G Šimić |
Journal of Alzheimer's disease : JAD | 2020 |
Associations between IL1RAP rs4624606, IL1RL1 rs1041973, IL-6 rs1800795, and HTRA1 rs11200638 gene polymorphisms and development of optic neuritis with or without multiple sclerosis
V Stonys, M Lindžiūtė, A Vilkevičiūtė, G Gedvilaitė, L Kriaučiūnienė, M Banevičius, R Žemaitienė, R Liutkevičienė |
Ophthalmic Genetics | 2020 |
Regulation of interleukin 6 by a polymorphic CpG within the frontal cortex in Alzheimer’s disease
X Sawkulycz, S Bradburn, A Robinson, A Payton, N Pendleton, C Murgatroyd |
Neurobiology of Aging | 2020 |
Promoter polymorphisms in IL-6 gene influence pro-inflammatory cytokines for the risk of osteoarthritis
M Singh, S Mastana, S Singh, PK Juneja, T Kaur, P Singh |
Cytokine | 2020 |
Association of interleukin1β, interleukin1 receptor antagonist, interleukin 6 and angiotensin II receptor type I gene polymorphisms with end stage renal disease: A meta-analysis
D Murugan, G Natarajan, S Natarajan, SB Stephen, S Varghese, Langeswaran, GK Subbaraj |
Gene Reports | 2020 |
Genetic polymorphism of the infl ammatory cytokines IL-1β and IL-6 in patients with serologically identifi ed atrophic gastritis
AV Belkovets, SA Kurilovich, VN Maksimov, LV Scherbakova |
2020 | |
Association between HER2 and IL-6 genes polymorphisms and clinicopathological characteristics of breast cancer: significant role of genetic variability in specific breast cancer subtype
OE Bouhniz, S Zaied, L Naija, I Bettaieb, K Rahal, M Driss, A Kenani |
Clinical and Experimental Medicine | 2020 |
Beyond the HLA polymorphism: A complex pattern of genetic susceptibility to pemphigus
ML Petzl-Erler |
Genetics and molecular biology | 2020 |
Pro-inflammatory cytokine response pre-dominates immuno-genetic pathway in development of rheumatoid arthritis
EK Priya, L Srinivas, S Rajesh, K Sasikala, M Banerjee |
Molecular Biology Reports | 2020 |
Cytokines and Their Genetic Polymorphisms Related to Periodontal Disease
M Kozak, E Dabrowska-Zamojcin, M Mazurek-Mochol, A Pawlik |
Journal of Clinical Medicine | 2020 |
β-Catenin and TCFs/LEF signaling discordantly regulate IL-6 expression in astrocytes
KR Robinson, SD Narasipura, J Wallace, EM Ritz, L Al-Harthi |
Cell Communication and Signaling | 2020 |
Gene polymorphisms and expression levels of interleukin-6 and interleukin-10 in lumbar disc disease: a meta-analysis and immunohistochemical study
Y Guan, S Wang, J Wang, D Meng, H Wu, Q Wei, H Jiang |
Journal of orthopaedic surgery and research | 2020 |
No Major Effect of Innate Immune Genetics on Acute Kidney Rejection in the First 2 Weeks Post-Transplantation
R Hu, DT Barratt, JK Coller, BC Sallustio, AA Somogyi |
Frontiers in pharmacology | 2020 |
Cytokine gene polymorphisms in Pigeon Breeder's Disease expression
Cláudia Freitas, Bruno Lima, Natália Martins, Natália Melo, Patrícia Mota, Hélder Novais-Bastos, Helena Alves, Oksana Sokhatska, Luís Delgado, António Morais |
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG | 2020 |
Autoinflammatory Pathogenesis and Targeted Therapy for Adult-Onset Still's Disease.
Li S, Zheng S, Tang S, Pan Y, Zhang S, Fang H, Qiao J |
Clinical Reviews in Allergy & Immunology | 2020 |
Risk Factors for Recurrent Colorectal Polyps.
Hao Y, Wang Y, Qi M, He X, Zhu Y, Hong J |
Gut and Liver | 2020 |
Real-Time Monitoring and Detection of Single-Cell Level Cytokine Secretion Using LSPR Technology.
Zhu C, Luo X, Espulgar WV, Koyama S, Kumanogoh A, Saito M, Takamatsu H, Tamiya E |
Micromachines | 2020 |
Association between interleukin gene polymorphisms and multiple myeloma susceptibility.
Shahzad MN, Ijaz I, Naqvi SSZH, Yan C, Lin F, Li S, Huang C |
Molecular and Clinical Oncology | 2020 |
Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database.
Ceschi A, Noseda R, Palin K, Verhamme K |
Frontiers in pharmacology | 2020 |
Association of IL-6 174G/C (rs1800795) and 572C/G (rs1800796) polymorphisms with risk of osteoporosis: a meta-analysis.
Chen B, Li HZ |
BMC musculoskeletal disorders | 2020 |
Interleukin Gene Variability and Periodontal Bacteria in Patients with Generalized Aggressive Form of Periodontitis.
Borilova Linhartova P, Danek Z, Deissova T, Hromcik F, Lipovy B, Szaraz D, Janos J, Fassmann A, Bartova J, Drizhal I, Izakovicova Holla L |
International journal of molecular sciences | 2020 |
Effects of the IL6 -174G>C promoter polymorphism and IL-6 serum levels on the progression of cutaneous malignant melanoma.
Vlaykova T, Kurzawski M, Tacheva T, Dimov D, Anastasov A, Vlaykova D, Miteva A, O'donoghue N, Drozdzik M |
Oncology Letters | 2020 |
Uncovering Outcome Disparities of β2 Adrenergic Agonists in Blacks: A Systematic Review.
Jerome RN, Pulley JM, Sathe NA, Krishnaswami S, Dickerson AB, Worley KJ, Lima MF, Wilkins CH |
Journal of the National Medical Association | 2020 |
Genetic Polymorphisms in Transforming Growth Factor-β, Interferon-γ and Interleukin-6 Genes and Susceptibility to Behcet's Disease in Saudi Population.
Al Okaily F, Alrashidi S, Mustafa M, Alrashdan FB |
Pharmacogenomics and Personalized Medicine | 2020 |
Interleukin-6 and Interleukin-10 Gene Polymorphisms in Patients with Chronic Periodontitis and Response to Treatment after 3 Years.
Chatzopoulos GS, Doufexi AE, Zarenti S, Anastasopoulos M, Kouvatsi A |
Acta Stomatologica Croatica | 2020 |
Clinical Management of Il-6 Driven Cytokine Storm Related to COVID-19 in a Patient with Recent Spinal Cord Stimulator Implants: A Case Report.
Papa A, Di Dato MT, Buonavolonta P, Saracco E, Salzano AM, Casale B |
Anesthesiology and Pain Medicine | 2020 |
Role of Interleukin-6 in Depressive Disorder.
Ting EY, Yang AC, Tsai SJ |
International journal of molecular sciences | 2020 |
IL6 genetic variants haplotype is associated with susceptibility and disease activity but not with therapy response in patients with inflammatory bowel disease.
Gonçalves BP, Flauzino T, Inoue CJ, de Paula JCC, Galvão TC, de Alcantara CC, Miyazaki PK, Rosa L, Westmore S, Lozovoy MAB, Reiche EMV, Simão ANC |
International Journal of Colorectal Disease | 2020 |
The role of IL-6-174 G/C polymorphism and intraocular IL-6 levels in the pathogenesis of ocular diseases: a systematic review and meta-analysis.
Ulhaq ZS, Soraya GV, Budu, Wulandari LR |
Scientific Reports | 2020 |
Single nucleotide polymorphism of transforming growth factor-β1 and interleukin-6 as risk factors for ovarian cancer.
Ahmed AB, Zidi S, Almawi W, Ghazouani E, Mezlini A, Loueslati BY, Stayoussef M |
2020 | |
The Perfect Storm: COVID-19 Health Disparities in US Blacks.
Phillips N, Park IW, Robinson JR, Jones HP |
Journal of Racial and Ethnic Health Disparities | 2020 |
Risk variants disrupting enhancers of T H 1 and T REG cells in type 1 diabetes
P Gao, Y Uzun, B He, SE Salamati, JK Coffey, E Tsalikian, K Tan |
Proceedings of the National Academy of Sciences | 2019 |
Influence of single nucleotide polymorphisms (SNPs) in genetic susceptibility towards periprosthetic osteolysis
S Jagga, AR Sharma, M Bhattacharya, C Chakraborty, SS Lee |
Genes & Genomics | 2019 |
Association of Chlamydia trachomatis, C. pneumoniae, and IL-6 and IL-8 Gene Alterations With Heart Diseases
NC Almeida, MA Queiroz, SS Lima, IB Costa, MA Fossa, AC Vallinoto, M de Oliveira Guimarães Ishak, R Ishak |
Frontiers in immunology | 2019 |
Racial Differences in Immunological Landscape Modifiers Contributing to Disparity in Prostate Cancer
JK Thomas, H Mir, N Kapur, S Singh |
Cancers | 2019 |
STAT3 polymorphisms and IL-6 polymorphism are associated with the risk of basal cell carcinoma in patients from northern Poland
M Sławińska, M Zabłotna, J Gleń, J Lakomy, RJ Nowicki, M Sobjanek |
Archives of Dermatological Research | 2019 |
Functions and regulation of T cell-derived interleukin-10
C Neumann, A Scheffold, S Rutz |
Seminars in Immunology | 2019 |
The combined polymorphisms of interleukin-6-174GG genotype and interleukin-10 ATA haplotype are associated with a poor quality of life in patients with chronic hepatitis C
DA Vieira, LR da Cunha, CB da Silva, MT Almeida, AD Gomes, , R Teixeira, FS Neves, GA Rocha, FF de Melo, DM de Magalhães Queiroz, LD Silva |
Quality of Life Research | 2019 |
Gene polymorphism associated with TNF-α (G308A) IL-6 (C174G) and susceptibility to coronary atherosclerotic heart disease: A meta-analysis
J Yuepeng, X Zhao, Y Zhao, L Li |
Medicine | 2019 |
The Role of Polymorphisms in Genes of PI3K/Akt Signaling Pathway on Prostate
W Xu, Z Ni, M Zhang, J Chen, L Zhang, S Wu, C Liang |
Journal of Cancer | 2019 |
Auto-Inflammatory Syndromes: Pathophysiology, Diagnosis, and Management
P Efthimiou |
2019 | |
Gene polymorphisms in the interleukins gene and the risk of acute pancreatitis: A meta-analysis
X Zhu, C Hou, M Tu, C Shi, L Yin, Y Peng, Q Li, Y Miao |
Cytokine | 2019 |
Association of Interleukin-6 -174G/C Polymorphism with the Risk of Diabetic Nephropathy in Type 2 Diabetes: A Meta-analysis
Z Cui, X Lu, K Xiao, Y Chen, H Li |
2019 | |
Helicobacter pylori and cytokine gene variants as predictors of premalignant gastric lesions
A Negovan, M Iancu, E Fülöp, C Bănescu |
World journal of gastroenterology : WJG | 2019 |
The combined polymorphisms of interleukin-6-174GG genotype and interleukin-10 ATA haplotype are associated with a poor quality of life in patients with chronic hepatitis C
DA Vieira, LR da Cunha, CB da Silva, MT Almeida, AD Gomes, CL de Faria, R Teixeira, FS Neves, GA Rocha, FF de Melo, DM de Magalhães Queiroz, LD Silva |
Quality of Life Research | 2019 |
Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overview
Z Heidari, B Moudi, H Mahmoudzadeh-Sagheb |
BMC oral health | 2019 |
Bead-type polystyrene/nano-CaCO 3 (PS/nCaCO 3 ) composite: a high-performance adsorbent for the removal of interleukin-6
Y Chai, J Chen, T Wang, J Chen, Y Ma, G Cheng, C Li, Q Zhang, L Ou, W Li |
Journal of Materials Chemistry B | 2019 |
Textbook of Autoinflammation
PJ Hashkes, RM Laxer, A Simon |
2019 | |
Genetic Polymorphisms in Sepsis and Cardiovascular Disease
T Nakada, W Takahashi, E Nakada, T Shimada, JA Russell, KR Walley |
Chest | 2019 |
The association between interleukin-6 gene -174G/C single nucleotide polymorphism and sepsis: an updated meta-analysis with trial sequential analysis
Y Chen, Y Hu, Z Song |
BMC Medical Genetics | 2019 |
Polymorphisms of cytokine genes and tuberculosis in two independent studies
S Wu, MG Wang, Y Wang, JQ He |
Scientific Reports | 2019 |
Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis
C Konwar, GF Gobbo, J Terry, WP Robinson |
BMC Medical Genetics | 2019 |
Molecular Diagnostics in Cancer Patients
KK Shukla, P Sharma, S Misra |
2019 | |
Autoinflammatory Pathogenesis and Targeted Therapy for Adult-Onset Still’s Disease
S Li, S Zheng, S Tang, Y Pan, S Zhang, H Fang, J Qiao |
Clinical Reviews in Allergy & Immunology | 2019 |
The role of damage-associated molecular pattern for pathogenesis and biomarkers in adult-onset Still’s disease
JY Jung, CH Suh, HA Kim |
Expert Review of Molecular Diagnostics | 2019 |
A longitudinal analysis of cytokines in anorexia nervosa
B Dalton, J Leppanen, IC Campbell, R Chung, G Breen, U Schmidt, H Himmerich |
Brain, Behavior, and Immunity | 2019 |
Potential Determinants of Gastrointestinal Dysfunction in Autism Spectrum Disorders
AE Shindler, EL Hill-Yardin, S Petrovski, AC Cunningham, N Bishop, AE Franks |
Review Journal of Autism and Developmental Disorders | 2019 |
Periodic and Non-Periodic Fevers
R Cimaz |
2019 | |
Inflammation-related genes are associated with epigenetic aging in HIV
EE Sundermann, MA Hussain, DJ Moore, S Horvath, DT Lin, MS Kobor, A Levine |
Journal of Neurovirology | 2019 |
Impact of interleukin-6 gene polymorphisms and its interaction with obesity on osteoporosis risk in Chinese postmenopausal women
YF Ji, X Jiang, W Li, X Ge |
Environmental Health and Preventive Medicine | 2019 |
Association between interleukin-6 gene polymorphisms and febrile seizure risk: A meta-analysis
Q Chen, M Li, X Zhang, X Zhang, R Zhong, W Lin |
Medicine | 2019 |
Association Between IL-6 Polymorphisms and Diabetic Nephropathy Risk: A Meta-analysis
B Chen, M Wu, C Zang, Y Li, Z Xu |
The American Journal of the Medical Sciences | 2019 |
Interleukin-6 gene polymorphisms and susceptibility to liver diseases: A meta-analysis
X Wang, Z Yan, Q Ye |
Medicine | 2019 |
Genetic Basis for the Dominance of Israeli Long-Distance Runners of Ethiopian Origin
S Ben-Zaken, Y Meckel, D Nemet, E Kassem, A Eliakim |
Journal of Strength and Conditioning Research | 2019 |
Genetic Association Analyses Highlight IL6 , ALPL , and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis
S Thériault, C Dina, D Messika-Zeitoun, SL Scouarnec, R Capoulade, N Gaudreault, S Rigade, Z Li, F Simonet, M Lamontagne, MA Clavel, BJ Arsenault, AS Boureau, S Lecointe, E Baron, S Bonnaud, M Karakachoff, E Charpentier, I Fellah, JC Roussel, JP Verhoye, C Baufreton, V Probst, R Roussel, R Redon, F Dagenais, P Pibarot, P Mathieu, TL Tourneau, Y Bossé, JJ Schott, B Balkau, P Ducimetière, E Eschwège, F Alhenc-Gelas, A Girault, F Fumeron, M Marre, F Bonnet, A Bonnefond, P Froguel, F Rancière, J Cogneau, C Born, E Caces, M Cailleau, O Lantieri, JG Moreau, F Rakotozafy, J Tichet, S Vol |
Circulation. Genomic and precision medicine | 2019 |
Functional polymorphisms within the inflammatory pathway regulate expression of extracellular matrix components in a genetic risk dependent model for anterior cruciate ligament injuries
MA Suijkerbuijk, M Ponzetti, M Rahim, M Posthumus, CK Häger, E Stattin, KG Nilsson, A Teti, DE Meuffels, BJ van der Eerden, M Collins, AV September |
Journal of Science and Medicine in Sport | 2019 |
Expression of suppressor of cytokine signaling 3 (SOCS3) and interleukin-6 (-174-G/C) polymorphism in atopic conditions
A Jannat, M Khan, M Shabbir, Y Badshah, L Chatenoud |
PloS one | 2019 |
Association between IL-6 polymorphisms and sepsis
P Hu, Y Chen, J Pang, X Chen |
Innate immunity | 2019 |
Cytokine Expression Patterns and Single Nucleotide Polymorphisms (SNPs) in Patients with Chronic Borreliosis
Hein, Sander, Giryes, Reinhardt, Hoegel, Schneider |
Antibiotics | 2019 |
Association study of single nucleotide polymorphisms in IL-10 and IL-17 genes with the severity of microbial keratitis
NA Carnt, V Cipriani, FJ Stapleton, V Calder, MD Willcox |
Contact Lens and Anterior Eye | 2019 |
The Effect of Habitual Fat Intake, IL6 Polymorphism, and Different Diet Strategies on Inflammation in Postmenopausal Women with Central Obesity
A Chmurzynska, A Muzsik, P Krzyżanowska-Jankowska, J Walkowiak, J Bajerska |
Nutrients | 2019 |
Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overview.
Heidari Z, Moudi B, Mahmoudzadeh-Sagheb H |
BMC oral health | 2019 |
The association between interleukin-6 gene -174G/C single nucleotide polymorphism and sepsis: an updated meta-analysis with trial sequential analysis.
Chen Y, Hu Y, Song Z |
BMC Medical Genetics | 2019 |
Polymorphisms of cytokine genes and tuberculosis in two independent studies.
Wu S, Wang MG, Wang Y, He JQ |
Scientific Reports | 2019 |
Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis.
Konwar C, Del Gobbo GF, Terry J, Robinson WP |
BMC Medical Genetics | 2019 |
Expression of suppressor of cytokine signaling 3 (SOCS3) and interleukin-6 (-174-G/C) polymorphism in atopic conditions.
Jannat A, Khan M, Shabbir M, Badshah Y |
PloS one | 2019 |
The Effect of Habitual Fat Intake, IL6 Polymorphism, and Different Diet Strategies on Inflammation in Postmenopausal Women with Central Obesity.
Chmurzynska A, Muzsik A, Krzyżanowska-Jankowska P, Walkowiak J, Bajerska J |
Nutrients | 2019 |
Impact of interleukin-6 gene polymorphisms and its interaction with obesity on osteoporosis risk in Chinese postmenopausal women.
Ji YF, Jiang X, Li W, Ge X |
Environmental Health and Preventive Medicine | 2019 |
Cytokine Expression Patterns and Single Nucleotide Polymorphisms (SNPs) in Patients with Chronic Borreliosis.
Hein TM, Sander P, Giryes A, Reinhardt JO, Hoegel J, Schneider EM |
2019 | |
Association between IL-6 polymorphisms and sepsis.
Hu P, Chen Y, Pang J, Chen X |
Innate immunity | 2019 |
Interleukin-6 gene polymorphisms and susceptibility to liver diseases: A meta-analysis.
Wang X, Yan Z, Ye Q |
Medicine | 2019 |
Association between Hepatitis C Virus Viremia and the rs12979860, rs2228145 and rs1800795 SNP (CT/AC/GG) Genotype in Saudi Kidney Transplant Recipients.
Alkharsah KR, Alzahrani AJ, Obeid OE, Aljindan RY, Guella A, Al-Ali AK, Al-Turaifi HR, Sallam TA |
2019 | |
Association between interleukin-6 gene polymorphisms and febrile seizure risk: A meta-analysis.
Chen Q, Li M, Zhang X, Zhang X, Zhong R, Lin W |
Medicine | 2019 |
Epidemic Myalgia Associated with Human Parechovirus Type 3 Infection.
Miyazaki M, Hara K, Takayoshi T, Kawase T, Nakagawa Y, Arai T, Sugimoto T, Nishiyama K, Gonzalez G, Hanaoka N, Fujimoto T, Yasutomo Y, Yokono K |
Internal Medicine | 2019 |
Meta-analysis and field synopsis of genetic variants associated with the risk and severity of acute pancreatitis.
van den Berg FF, Kempeneers MA, van Santvoort HC, Zwinderman AH, Issa Y, Boermeester MA |
2019 | |
Streptococcal pharyngitis and rheumatic heart disease: the superantigen hypothesis revisited
JR Hurst, KJ Kasper, AN Sule, JK McCormick |
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases | 2018 |
The Two-Faced Cytokine IL-6 in Host Defense and Diseases
M Narazaki, T Kishimoto |
International journal of molecular sciences | 2018 |
Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines
IM Rea, DS Gibson, V McGilligan, SE McNerlan, HD Alexander, OA Ross |
Frontiers in immunology | 2018 |
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
DE Johnson, RA O'Keefe, JR Grandis |
Nature Reviews Clinical Oncology | 2018 |
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
L Ferrucci, E Fabbri |
Nature Reviews Cardiology | 2018 |
Genetic Polymorphisms Associated with Spontaneous Intracerebral Hemorrhage
YC Chen, KH Chang, CM Chen |
International journal of molecular sciences | 2018 |
Interleukin 6 and 10 Serum Levels and Genetic Polymorphisms in Children with Down Syndrome
MF Mattos, PM Biselli-Chicote, JM Biselli, TL da Silva Assembleia, EM Goloni-Bertollo, ÉC Pavarino |
Mediators of Inflammation | 2018 |
Inflammatory Profiles of the Interleukin Family and Network in Cerebral Hemorrhage
L Ye, L Gao, H Cheng |
Cellular and Molecular Neurobiology | 2018 |
IL-27: a double agent in the IL-6 family: IL-27 and IL-6 in inflammatory arthritis
GW Jones, DG Hill, A Cardus, SA Jones |
Clinical & Experimental Immunology | 2018 |
Interleukin-6 significantly improves predictive value of systemic inflammatory response syndrome for predicting severe acute pancreatitis
S Jain, S Midha, SJ Mahapatra, S Gupta, MK Sharma, B Nayak, TG Jacob, Shalimar, PK Garg |
Pancreatology | 2018 |
A novel predictive approach for GVHD after allogeneic SCT based on clinical variables and cytokine gene polymorphisms
C Martínez-Laperche, E Buces, MC Aguilera-Morillo, A Picornell, M González-Rivera, R Lillo, N Santos, B Martín-Antonio, V Guillem, JB Nieto, M González, R de la Cámara, S Brunet, A Jiménez-Velasco, I Espigado, C Vallejo, A Sampol, JM Bellón, D Serrano, M Kwon, J Gayoso, P Balsalobre, Á Urbano-Izpizua, C Solano, D Gallardo, JL Díez-Martín, J Romo, I Buño |
Blood Advances | 2018 |
Novel Anti-arthritic Mechanisms of Polydatin in Complete Freund's Adjuvant-Induced Arthritis in Rats: Involvement of IL-6, STAT-3, IL-17, and NF-кB.
Kamel KM, Gad AM, Mansour SM, Safar MM, Fawzy HM |
Inflammation | 2018 |
Association between the -174 C/G polymorphism in the interleukin-6 (IL-6) gene and gastrointestinal involvement in patients with systemic sclerosis
A Zekovic, M Vreca, V Spasovski, M Andjelkovic, S Pavlovic, N Damjanov |
Clinical Rheumatology | 2018 |
− 174 G>C IL-6 polymorphism and primary iron overload in male patients
WF Tetzlaff, T Meroño, EE Botta, ME Martín, PB Sorroche, LE Boero, M Castro, GD Frechtel, J Rey, J Daruich, GE Cerrone, F Brites |
Annals of Hematology | 2018 |
Control of Listeria monocytogenes infection requires classical IL-6 signaling in myeloid cells
K Lücke, I Yan, S Krohn, A Volmari, S Klinge, J Schmid, V Schumacher, OM Steinmetz, S Rose-John, HW Mittrücker, ME Rottenberg |
PloS one | 2018 |
Adult-Onset Still’s Disease: Molecular Pathophysiology and Therapeutic Advances
P Sfriso, S Bindoli, P Galozzi |
Drugs | 2018 |
Genetic Polymorphisms of IL1B, IL6, and TNF α in a Chinese Han Population with Pulmonary Tuberculosis
S Wu, Y Wang, M Zhang, SS Shrestha, M Wang, JQ He |
BioMed Research International | 2018 |
Handbook of Immunosenescence: Basic Understanding and Clinical Implications
T Fulop, C Franceschi, K Hirokawa, G Pawelec |
Handbook of Immunosenescence | 2018 |
Methylation Status of Interleukin-6 Gene Promoter in Patients with Behçet's Disease
S Alipour, E Sakhinia, A Khabbazi, N Samadi, Z Babaloo, M Azad, S Abolhasani, J Farhadi, G Jadideslam, N Roshanravan, M Nouri |
Reumatología Clínica | 2018 |
Interleukin 6 gene polymorphism is associated with protein serum level and disease activity in Polish patients with rheumatoid arthritis
J Wielińska, M Dratwa, J Świerkot, L Korman, M Iwaszko, B Wysoczańska, K Bogunia-Kubik |
HLA | 2018 |
Lack of association between single-nucleotide polymorphisms of pro- and anti-inflammatory cytokines and HTLV-1-associated myelopathy / tropical spastic paraparesis development in patients from Rio de Janeiro, Brazil
D Schor, LC Porto, EH Roma, M de Souza Borges Quintana, GM Fabricio-Silva, MG Bonecini-Almeida, AQ Araújo, MJ Andrada-Serpa |
BMC Infectious Diseases | 2018 |
Allelic Combinations of Immune Response Genes and Risk of Development of Myocardial Infarction
RI Sadikova, TR Nasibullin, YR Timasheva, IA Tuktarova, VV Erdman, MI Shein, IE Nikolaeva, OE Mustafina |
Russian Journal of Genetics | 2018 |
No association of IL2, IL4, IL6, TNF , and IFNG gene polymorphisms was found with Taenia solium human infection or neurocysticercosis severity in a family-based study
A Fleury, C Alaez, A Dessein, M Rosetti, B Saenz, M Hernández, RJ Bobes, R Ramírez-Aquino, E Sciutto, C Gorodezky, G Fragoso |
Human Immunology | 2018 |
Inflammatory and apoptotic signalling pathways and concussion severity: a genetic association study
SM Fie, S Abrahams, J Patricios, J Suter, M Posthumus, AV September |
Journal of Sports Sciences | 2018 |
IL1RN Variation Influences Both Disease Susceptibility and Response to Recombinant Human Interleukin-1 Receptor Antagonist Therapy in Systemic Juvenile Idiopathic Arthritis
VL Arthur, E Shuldiner, EF Remmers, A Hinks, AA Grom, D Foell, A Martini, M Gattorno, S Özen, S Prahalad, AS Zeft, JF Bohnsack, NT Ilowite, ED Mellins, R Russo, C Len, S Oliveira, RS Yeung, AM Rosenberg, LR Wedderburn, J Anton, JP Haas, A Rösen-Wolff, K Minden, AM Szymanski, W Thomson, DL Kastner, P Woo, MJ Ombrello |
Arthritis & Rheumatology | 2018 |
Association between rs1800795 polymorphism in the interleukin-6 gene and the risk of polycystic ovary syndrome: A meta-analysis
L Chen, Z Zhang, J Huang, M Jin |
Medicine | 2018 |
Influence of cytokine gene polymorphism on the risk of rheumatic heart disease – A meta-analysis
M Bhatt, S Kumar, MH Siddiqui, N Garg, B Mittal |
Immunology Letters | 2018 |
The association between interleukin polymorphism and recurrent aphthous stomatitis: A meta-analysis
D Wu, J Xin, J Liu, P Zhou |
Archives of Oral Biology | 2018 |
Polymorphic Variants of Immune Response Genes as a Risk Factor for the Development of Primary Progressive Multiple Sclerosis
EV Popova, IS Kiselev, AN Boiko, SA Sivertseva, NA Malkova, DS Korobko, NN Spirin, DS Kasatkin, AV Karaeva, EL Turova, NN Spirina, LI Volkova, NM Baulina, VV Bashinskaya, OG Kulakova, OO Favorova |
Neuroscience and Behavioral Physiology | 2018 |
Impact of interleukin 6 promoter polymorphisms (−174 G > C, −572 G > C and −597 G > A) on plasma IL-6 levels and their influence on the development of DVT: a study from India
A Sharma, K Singh, A Biswas, R Ranjan, K Kishor, H Pandey, R Kumar, M Mahapatra, J Oldenburg, R Saxena |
Hematology | 2018 |
From traditional biochemical signals to molecular markers for detection of sepsis after burn injuries
B Muñoz, R Suárez-Sánchez, O Hernández-Hernández, R Franco-Cendejas, H Cortés, JJ Magaña |
Burns : journal of the International Society for Burn Injuries | 2018 |
A pilot study of single nucleotide polymorphisms in the interleukin-6 receptor and their effects on pre- and post-transplant serum mediator level and outcome after allogeneic stem cell transplantation: SNPs in the IL-6R and allotransplantation
TH Tvedt, R Hovland, G Tsykunova, AB Ahmed, T Gedde-Dahl, Ø Bruserud |
Clinical & Experimental Immunology | 2018 |
PPARG2 Pro12Ala polymorphism influences body composition changes in severely obese patients consuming extra virgin olive oil: a randomized clinical trial
AP Rodrigues, LP Rosa, EA Silveira |
Nutrition & Metabolism | 2018 |
Association of the Interleukin-6 rs1800795 Polymorphism with Type 2 Diabetes Mellitus in the Population of the Island of Crete, Greece
MN Plataki, MI Zervou, G Samonis, V Daraki, GN Goulielmos, DP Kofteridis |
Genetic Testing and Molecular Biomarkers | 2018 |
The association between periodontitis and interleukin-6 genetic polymorphism -174 G/C: A meta-analysis
B Zhao, R Li |
Archives of Oral Biology | 2018 |
Novel Anti-arthritic Mechanisms of Polydatin in Complete Freund’s Adjuvant-Induced Arthritis in Rats: Involvement of IL-6, STAT-3, IL-17, and NF-кB
KM Kamel, AM Gad, SM Mansour, MM Safar, HM Fawzy |
Inflammation | 2018 |
Genetics Factors in Major Depression Disease
M Shadrina, EA Bondarenko, PA Slominsky |
Frontiers in Psychiatry | 2018 |
Genetics and genomics in postoperative pain and analgesia:
V Palada, MA Kaunisto, E Kalso |
Current Opinion in Anaesthesiology | 2018 |
Genetic Variants and Hamstring Injury in Soccer: An Association and Validation Study
J Larruskain, DA Celorrio, I Barrio, A Odriozola, SM Gil, JR Fernandez-Lopez, R Nozal, I Ortuzar, JA Lekue, JM Aznar |
Medicine and Science in Sports and Exercise | 2018 |
Association of IL-6 -174G>C (rs1800795) polymorphism with cervical cancer susceptibility
HX Duan, YY Chen, JZ Shi, NN Ren, XJ Li |
Bioscience Reports | 2018 |
Effects of increasing ratios of dietary omega-6/omega-3 fatty acids on human monocyte immunomodulation linked with atherosclerosis
AA Alshatwi, P Subash-Babu |
Journal of Functional Foods | 2018 |
Serum Interleukin-6 Level and the rs1800795 Polymorphism in its Gene Associated with Neuroblastoma Risk in Chinese Children:
Q Zhao, M Jin, DW Zhang, W Zhao, , ZX Yue, C Duan, C Huang, XL Ma |
Chinese Medical Journal | 2018 |
Significant association of IL-6-572G/C, IL-6-597G/A, and IL-6-174G/C polymorphisms and susceptibility to lumbar degenerative disease: A meta-analysis
S Gao, T Xu, C Xun, W Liang, R Cao, C Mao, W Sheng |
Clinical Neurology and Neurosurgery | 2018 |
Influence of -174G/C IL-6 gene polymorphism on the susceptibility to rheumatoid arthritis in children and adults in the Republic Of Belarus
HA Yatskiu, DV Balshakova, AM Tchitchko, VE Yagur, AV Sukalo, RI Goncharova |
2018 | |
Association between Genes for Inflammatory Factors and Neuroticism, Anxiety, and Depression in Men with Ischemic Heart Disease
VE Golimbet, BA Volel, GI Korovaitseva, SV Kasparov, NV Kondratev, FY Kopylov |
Neuroscience and Behavioral Physiology | 2018 |
Cardiovascular Disease: Diet, Nutrition and Emerging Risk Factors
S Stanner, S Coe, KN Frayn |
2018 | |
Frailty as an Outcome Predictor After Ankle Fractures: Where Are We Now?
M Mediouni, DR Schlatterer |
Geriatric Orthopaedic Surgery & Rehabilitation | 2018 |
Association of Interleukin-4 (-590 C/T) and Interleukin-6 (-174 G/C) Polymorphism in Pathogenesis and Prognosis of Hepatitis C Virus Infection
Y Badshah, N Arshad, M Khan, A Jannat, H Hayat |
Journal of Interferon & Cytokine Research | 2018 |
Analysis of association of -174G/C interleukin 6 polymorphism and therapeutic response to methotrexate in rheumatoid arthritis
A Joksimović, C Khouri, B Jekić |
2018 | |
Interleukin-6 in juvenile idiopathic arthritis
S Akioka |
Modern Rheumatology | 2018 |
A pilot study of single nucleotide polymorphisms in the interleukin-6 receptor and their effects on pre- and post-transplant serum mediator level and outcome after allogeneic stem cell transplantation.
Tvedt THA, Hovland R, Tsykunova G, Ahmed AB, Gedde-Dahl T, Bruserud Ø |
Clinical & Experimental Immunology | 2018 |
IL1RN Variation Influences Both Disease Susceptibility and Response to Recombinant Human Interleukin-1 Receptor Antagonist Therapy in Systemic Juvenile Idiopathic Arthritis.
Arthur VL, Shuldiner E, Remmers EF, Hinks A, Grom AA, Foell D, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Ilowite NT, Mellins ED, Russo R, Len C, Oliveira S, Yeung RSM, Rosenberg AM, Wedderburn LR, Anton J, Haas JP, Rösen-Wolff A, Minden K, Szymanski AM, Thomson W, Kastner DL, Woo P, Ombrello MJ |
Arthritis & Rheumatism | 2018 |
Association between rs1800795 polymorphism in the interleukin-6 gene and the risk of polycystic ovary syndrome: A meta-analysis.
Chen L, Zhang Z, Huang J, Jin M |
Medicine | 2018 |
PPARG2 Pro12Ala polymorphism influences body composition changes in severely obese patients consuming extra virgin olive oil: a randomized clinical trial.
Rodrigues APS, Rosa LPS, Silveira EA |
Nutrition & Metabolism | 2018 |
Genetics Factors in Major Depression Disease.
Shadrina M, Bondarenko EA, Slominsky PA |
Frontiers in Psychiatry | 2018 |
Polymorphism of IFN-γ +874T/A associated with production of IFN-γ affects human papillomavirus susceptibility in rural women from Luohe, Henan, China.
Zhang QW, Song JY, Yu JH, Sun MZ, Tang SY, Yang SZ, Cao LJ, Wang HF, Cui LN, Fu XH |
OncoTargets and therapy | 2018 |
Association of IL-6 -174G>C (rs1800795) polymorphism with cervical cancer susceptibility.
Duan HX, Chen YY, Shi JZ, Ren NN, Li XJ |
Bioscience Reports | 2018 |
The relationship between 174 G/C and -572 G/C of IL-6 gene polymorphisms and susceptibility of celiac disease in the Iranian population.
Barartabar Z, Nikzamir A, Sirati-Sabet M, Aghamohammadi E, Chaleshi V, Rostami Nejad M, Asadzadeh-Aghdaei H, Reza Zali M |
2018 | |
Interleukin-6 gene -572G/C polymorphism and prostate cancer risk.
Wang Y, Chen X, Chen Y |
African health sciences | 2018 |
Association between polymorphism of tumor necrosis factor alpha (tnfα) in the region -308 g/a with tinnitus in the elderly with a history of occupational noise exposure.
Marchiori LLM, Dias ACM, Gonçalvez AS, Poly-Frederico RC, Doi MY |
Noise & health | 2018 |
Interleukin-6 in Allogeneic Stem Cell Transplantation: Its Possible Importance for Immunoregulation and As a Therapeutic Target
TH Tvedt, E Ersvaer, AA Tveita, Ø Bruserud |
Frontiers in immunology | 2017 |
Polymorphisms in inflammation-related genes and the risk of primary varicose veins in ethnic Russians
A Shadrina, E Voronina, M Smetanina, Y Tsepilov, K Sevostianova, A Shevela, E Seliverstov, E Zakharova, E Ilyukhin, A Kirienko, I Zolotukhin, M Filipenko |
Immunologic Research | 2017 |
Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators
HN Nguyen, EH Noss, F Mizoguchi, C Huppertz, KS Wei, GF Watts, MB Brenner |
Immunity | 2017 |
Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology
CJ Pyle, FI Uwadiae, DP Swieboda, JA Harker, CB Lopez |
PLoS pathogens | 2017 |
Interleukin-6 Genetic Variation and Susceptibility to Gastric Cancer in an Iranian Population
Marzieh Attar, Maryam Mansoori, Majid Shahbazi |
Asian Pacific Journal of Cancer Prevention | 2017 |
Kelley and Firestein's Textbook of Rheumatology
PE di Cesare, DR Haudenschild, J Samuels, SB Abramson |
Kelley and Firestein's Textbook of Rheumatology | 2017 |
IL-6 rs1800795 polymorphism is associated with septic shock-related death in patients who underwent major surgery: a preliminary retrospective study
MA Jiménez-Sousa, LM Medrano, P Liu, A Fernández-Rodríguez, R Almansa, E Gomez-Sanchez, A Ortega, M Heredia-Rodríguez, E Gómez-Pesquera, E Tamayo, S Resino |
Annals of Intensive Care | 2017 |
Genetic predictors of long-term graft function in kidney and pancreas transplant patients
CE Duff, MJ Simmonds |
Briefings in Functional Genomics | 2017 |
Influence of IL1B , IL6 and IL10 gene variants and plasma fatty acid interaction on metabolic syndrome risk in a cross-sectional population-based study
MM Norde, E Oki, AA Carioca, NR Damasceno, RM Fisberg, DM Marchioni, MM Rogero |
Clinical Nutrition | 2017 |
The Relevance of Coding Gene Polymorphysms of Cytokines and Cellular Receptors in Sepsis
AM Georgescu, BL Grigorescu, IR Chirteș, AA Vitin, RȘ Fodor |
The Journal of Critical Care Medicine | 2017 |
Interleukin-6 -572C/G polymorphism is associated with serum interleukin-6 levels and risk of idiopathic pulmonary arterial hypertension
M Fang, Y Huang, Y Zhang, Z Ning, L Zhu, X Li |
Journal of the American Society of Hypertension | 2017 |
A 21-Month-Old Male With Refusal to Walk, Rash, and Weight Loss: Clinicopathologic Conference
T Reese, L Villegas, J Wood, A Gotte |
Arthritis Care & Research | 2017 |
Association of SNPs from IL1A , IL1B , and IL6 Genes with Human Cytomegalovirus Infection Among Pregnant Women
WI Wujcicka, JS Wilczyński, DE Nowakowska |
Viral Immunology | 2017 |
Morbus Still im Kindes- und Erwachsenenalter
CM Hedrich, C Günther, M Aringer |
Der Hautarzt | 2017 |
Biomedical Risk Factors of Achilles Tendinopathy in Physically Active People: a Systematic Review
M Kozlovskaia, N Vlahovich, KJ Ashton, DC Hughes |
Sports Medicine - Open | 2017 |
IL-6 variant is associated with metastasis in breast cancer patients
CO Abana, BS Bingham, JH Cho, AJ Graves, T Koyama, RT Pilarski, AB Chakravarthy, F Xia, WB Coleman |
PloS one | 2017 |
Morbus Still im Kindes- und Erwachsenenalter
CM Hedrich, C Günther, M Aringer |
Zeitschrift für Rheumatologie | 2017 |
Study of IL4-590C/T and IL6-174G/C Gene Polymorphisms in Type 2 Diabetic Patients With Chronic Kidney Disease in North Indian Population: G ENE P OLYMORPHISM IN D IABETIC P ATIENTS
K Neelofar, J Ahmad, A Ahmad, K Alam |
Journal of Cellular Biochemistry | 2017 |
Effect of maternal and neonatal interleukin-6 − 174 G/C polymorphism on preterm birth and neonatal morbidity
NM Karakaş, AN Ecevit, Y Yalçın, B Özdemir, H Verdi, MA Tekindal, NY Özbek, A Tarcan, FB Ataç, A Haberal |
Journal of Maternal-Fetal and Neonatal Medicine | 2017 |
Interleukin 6 gene polymorphism in patients with degenerative lumbar scoliosis: a cohort study
JS Lee, JK Shin, TS Goh |
European Spine Journal | 2017 |
Association of inflammatory genes with neuroticism, anxiety and depression in male patients with coronary heart disease
VE Golimbet, BA Volel, GI Korovaitseva, SV Kasparov, NV Kondratiev, FY Kopylov |
ZH NEVROL PSIKHIATR | 2017 |
The profile of selected single nucleotide polymorphisms in patients with hypertension and heart failure with preserved and mid-range ejection fraction
A Bielecka-Dabrowa, A Sakowicz, T Pietrucha, M Misztal, P Chruściel, J Rysz, M Banach |
Scientific Reports | 2017 |
Increased Prevalence of the IL-6 -174C Genetic Polymorphism in Long Distance Swimmers
S Ben-Zaken, Y Meckel, D Nemet, E Kassem, A Eliakim |
Journal of Human Kinetics | 2017 |
IL-6 and IL-10 gene polymorphisms in patients with aggressive periodontitis: effects on GCF, serum and clinic parameters
EP GORGUN, H TOKER, EM KORKMAZ, O POYRAZ |
Brazilian Oral Research | 2017 |
The role and therapeutic targeting of IL-6 in rheumatoid arthritis
M Narazaki, T Tanaka, T Kishimoto |
Expert Review of Clinical Immunology | 2017 |
Association of IL - 6 -174 G>C polymorphism with the risk of SLE among south Indians: evidence from case–control study and meta-analysis
SK Katkam, L Rajasekhar, K Kumaraswami, VK Kutala |
Lupus | 2017 |
Influence of the IL6 − 147C/G polymorphism on clinical characteristics of chronic hepatitis C in Brazilian patients
AA Maya, CF da Alves, CG Marangon, K Frizon, RP Gorziza, VR Lunge, D Simon |
Gene Reports | 2017 |
Polymorphic variants of the immune response genes as risk factors for primary progressive multiple sclerosis
EV Popova, IS Kiselev, AN Boyko, SA Sivertseva, NA Malkova, DS Korobko, NN Spirin, DS Kasatkin, AV Karaeva, EL Turova, NN Spirina, LI Volkova, NM Baulina, VV Bashinskaya, OG Kulakova, OO Favorova |
ZH NEVROL PSIKHIATR | 2017 |
Association study of interleukin-1 family, interleukin-6, and its receptor gene polymorphisms in patients with recurrent aphthous stomatitis
LI Holla, S Valova, PB Linhartova, J Bartova, J Petanova, P Kuklinek, A Fassmann |
Journal of Oral Pathology & Medicine | 2017 |
Influence of TNF and IL6 gene polymorphisms on the severity of cytopenias in Argentine patients with myelodysplastic syndromes
Y Bestach, VP Nagore, MG Flores, J González, J Arbelbide, N Watman, Y Sieza, I Larripa, C Belli |
Annals of Hematology | 2017 |
Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression
J Ryan, L Pilkington, K Neuhaus, K Ritchie, ML Ancelin, R Saffery |
BMC psychiatry | 2017 |
Polymorphisms in immune-inflammatory response genes and the risk of deficit schizophrenia
M Mak, B Misiak, D Frydecka, J Pełka-Wysiecka, J Kucharska-Mazur, A Samochowiec, P Bieńkowski, E Pawlak-Adamska, L Karabon, E Szmida, P Skiba, K Kotowicz, P Piotrowski, JA Beszłej, J Samochowiec |
Schizophrenia Research | 2017 |
Impact of cytokine genetic polymorphisms on the risk of renal parenchymal infection in children
A Hussein, E Askar, A Badawy, K Saad, A Zahran, AA Elderwy |
Journal of Pediatric Urology | 2017 |
Update on the management of systemic juvenile idiopathic arthritis and role of IL-1 and IL-6 inhibition
S Grevich, S Shenoi |
Adolescent health, medicine and therapeutics | 2017 |
Genetic association of pro-inflammatory cytokine gene polymorphisms with coronary artery disease (CAD) in a North Indian population
S Mastana, S Prakash, EC Akam, M Kirby, MR Lindley, N Sinha, S Agrawal |
Gene | 2017 |
Interleukin-6-174G>C gene promoter polymorphism and prognosis in patients with cancer
K Zhai, Y Yang, ZG Gao, J Ding |
Oncotarget | 2017 |
Genetic variants in gastric cancer: Risks and clinical implications
CO Gigek, DQ Calcagno, LT Rasmussen, LC Santos, MF Leal, F Wisnieski, RR Burbano, LG Lourenço, GJ Lopes-Filho, MA Smith |
Experimental and Molecular Pathology | 2017 |
Regulation of Inflammatory Signaling in Health and Disease
D Xu |
Regulation of Inflammatory Signaling in Health and Disease | 2017 |
Pathogenesis of Periodontal Diseases
N Bostanci, GN Belibasakis |
Pathogenesis of Periodontal Diseases | 2017 |
Role of TLRs and IL-6 in the outcome of chronic hepatitis C treatment in Tunisian population
I Sghaier, L Mouelhi, E Ghazoueni, E Brochot, WY Almawi, B Yacoubi-Loueslati |
Cytokine | 2017 |
Multiple sclerosis genetics: Results from meta-analyses of candidate-gene association studies
K Tizaoui |
Cytokine | 2017 |
Handbook of Immunosenescence
T Fulop, C Franceschi, K Hirokawa, G Pawelec |
Handbook of Immunosenescence | 2017 |
Genetic variants and acute kidney injury: A review of the literature
DB Larach, MC Engoren, EM Schmidt, M Heung |
Journal of Critical Care | 2017 |
Association of cytokine gene polymorphisms with bronchopulmonary dysplasia in Han Chinese newborns
H Chen, W Zheng |
Pediatric Pulmonology | 2017 |
Estrogen Metabolism-Associated CYP2D6 and IL6-174G/C Polymorphisms in Schistosoma haematobium Infection
R Cardoso, P Lacerda, P Costa, A Machado, A Carvalho, A Bordalo, R Fernandes, R Soares, J Richter, H Alves, M Botelho |
International journal of molecular sciences | 2017 |
Noncoding RNAs: Master Regulators of Inflammatory Signaling
CL Chew, SA Conos, B Unal, V Tergaonkar |
Trends in Molecular Medicine | 2017 |
Association of IL-6-174 G/C and IL10-1082 G/A polymorphisms with recurrent aphthous stomatitis risk: A meta-analysis
S Yang, B Zhang, Q Shi, J Liu, J Xu, N Huo |
Medicine | 2017 |
Genetic polymorphisms associated with the risk of concussion in 1056 college athletes: a multicentre prospective cohort study
TR Terrell, R Abramson, JT Barth, E Bennett, RC Cantu, R Sloane, DT Laskowitz, DM Erlanger, D McKeag, G Nichols, V Valentine, L Galloway |
British journal of sports medicine | 2017 |
Analysis of IL-6, IL-10 and NF-κB Gene Polymorphisms in Aggressive and Chronic Periodontitis
H Toker, EP Görgün, EM Korkmaz |
CENT EUR J PUBL HEAL | 2017 |
The association between interleukin 6 −174 G/C gene polymorphism and the risk of osteoporosis: A meta-analysis
JK Fajar, A Azharuddin |
Journal of Taibah University Medical Sciences | 2017 |
Interleukin 6 gene polymorphism in patients with degenerative lumbar scoliosis: a cohort study.
Lee JS, Shin JK, Goh TS |
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society | 2017 |
Estrogen Metabolism-Associated CYP2D6 and IL6-174G/C Polymorphisms in Schistosoma haematobium Infection.
Cardoso R, Lacerda PC, Costa PP, Machado A, Carvalho A, Bordalo A, Fernandes R, Soares R, Richter J, Alves H, Botelho MC |
International journal of molecular sciences | 2017 |
The Relevance of Coding Gene Polymorphysms of Cytokines and Cellular Receptors in Sepsis.
Georgescu AM, Grigorescu BL, Chirteș IR, Vitin AA, Fodor RȘ |
2017 | |
Association of IL-6-174 G/C and IL10-1082 G/A polymorphisms with recurrent aphthous stomatitis risk: A meta-analysis.
Yang S, Zhang B, Shi Q, Liu J, Xu J, Huo N |
Medicine | 2017 |
Association of IL-6 C-572G Gene Polymorphism with Anti-E Production.
Lin JS, Lee LH, Liu HM, Chen YJ, Chiou TJ |
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie | 2017 |
Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
J White, G Smythe |
2016 | |
Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
J White, G Smythe |
2016 | |
Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
J White, G Smythe |
2016 | |
Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
J White, G Smythe |
2016 | |
Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
J White, G Smythe |
2016 | |
Aging, inflammation, immunity and periodontal disease
JL Ebersole, CL Graves, OA Gonzalez, D Dawson, LA Morford, PE Huja, JK Hartsfield, SS Huja, S Pandruvada, SM Wallet |
Periodontology 2000 | 2016 |
Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing
P Baumert, MJ Lake, CE Stewart, B Drust, RM Erskine |
European Journal of Applied Physiology | 2016 |
Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis
X Dong, A Cheng, Z Zou, YS Yang, RM Sumpter, CL Huang, G Bhagat, HW Virgin, SA Lira, B Levine |
Proceedings of the National Academy of Sciences | 2016 |
IL-6 blockers in systemic onset juvenile idiopathic arthritis
P Barone, R Pignataro, MT Garozzo, S Leonardi |
Immunotherapy | 2016 |
Inflammatory Cytokines and Alzheimer’s Disease: A Review from the Perspective of Genetic Polymorphisms
F Su, F Bai, Z Zhang |
Neuroscience Bulletin | 2016 |
Is the IL-6 -174G/C Gene Polymorphism Related to the Disease Severity Score in Turkish Children with Familial Mediterranean Fever?
S Özer, R Yilmaz, E Sonmezgoz, Ş Ünuvar, Ö Ates |
Biochemical Genetics | 2016 |
Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome
J Yan, G JM, MC PA |
Journal of Neuroimmunology | 2016 |
Caspase-1 als Regulator der Autoinflammation bei rheumatischen Erkrankungen
S Winkler, CM Hedrich, A Rösen-Wolff |
Zeitschrift für Rheumatologie | 2016 |
Shaping the spectrum — From autoinflammation to autoimmunity
CM Hedrich |
Clinical Immunology | 2016 |
Textbook of Pediatric Rheumatology
E Silverman, J Buyon, E Jaeggi |
Textbook of Pediatric Rheumatology | 2016 |
Tocilizumab for treating juvenile idiopathic arthritis
JL Turnier, HI Brunner |
Expert Opinion on Biological Therapy | 2016 |
Interleukin 6 (IL-6) and IL-10 Promoter Region Polymorphisms Are Associated with Risk of Lumbar Disc Herniation in a Northern Chinese Han Population
X Huang, F Chen, J Zhao, D Wang, S Jing, H Li, C Meng |
Genetic Testing and Molecular Biomarkers | 2016 |
Interventions for age-related diseases: shifting the paradigm
I Figueira, A Fernandes, A Mladenovic, A Lopez-Contreras, CM Henriques, C Selman, E Ferreiro, ES Gonos, JL Trejo, J Misra, LJ Rasmussen, S Xapelli, T Ellam, I Bellantuono |
Mechanisms of Ageing and Development | 2016 |
The Innate Immune Response to Non-Infectious Stressors
S González, C López-Larrea, A López-Soto |
The Innate Immune Response to Non-Infectious Stressors | 2016 |
Pediatric Rheumatology
S Sawhney, A Aggarwal |
Pediatric Rheumatology | 2016 |
Regulation of Cytokine Gene Expression in Immunity and Diseases
X Ma |
Regulation of Cytokine Gene Expression in Immunity and Diseases | 2016 |
Meta-analysis of the Correlation Between Interleukin-6 Promoter Polymorphism -174G/C and Interferon Regulatory Factor 4 rs12203592 Polymorphism With Skin Cancer Susceptibility:
M Wu, Y Cao, Y Liu, L Ma, X Yang |
American Journal of Therapeutics | 2016 |
Hall of Fame among Pro-inflammatory Cytokines: Interleukin-6 Gene and Its Transcriptional Regulation Mechanisms
Y Luo, SG Zheng |
Frontiers in immunology | 2016 |
Mitochondrial and oxidative stress genes are differentially expressed in neutrophils of sJIA patients treated with tocilizumab: a pilot microarray study
E Omoyinmi, R Hamaoui, A Bryant, MC Jiang, T Athigapanich, D Eleftheriou, M Hubank, P Brogan, P Woo |
Pediatric Rheumatology | 2016 |
Single Nucleotide Polymorphisms in IL17A and IL6 Are Associated with Decreased Risk for Pulmonary Tuberculosis in Southern Brazilian Population
M Milano, MO Moraes, R Rodenbusch, CX Carvalho, M Delcroix, G Mousquer, LL da Costa, G Unis, ER Costa, ML Rossetti, S Subbian |
PloS one | 2016 |
Association between Interleukin-6 Promoter Polymorphism (-174 G/C), Serum Interleukin-6 Levels and Mortality in Severe Septic Patients
L Lorente, M Martín, A Pérez-Cejas, Y Barrios, J Solé-Violán, J Ferreres, L Labarta, C Díaz, A Jiménez |
International journal of molecular sciences | 2016 |
Association of genetic polymorphisms in interferon-γ, interleukin-6 and transforming growth factor-β1 gene with oral lichen planus susceptibility
MA Al-Mohaya, L Al-Otaibi, F Al-Harthi, EA Bakr, M Arfin, A Al-Asmari |
BMC oral health | 2016 |
Identification of IL6 as a susceptibility gene for major depressive disorder
C Zhang, Z Wu, G Zhao, F Wang, Y Fang |
Scientific Reports | 2016 |
Pro-inflammatory cytokines and their epistatic interactions in genetic susceptibility to schizophrenia
L Srinivas, NN Vellichirammal, AM Alex, C Nair, IV Nair, M Banerjee |
Journal of Neuroinflammation | 2016 |
Association Between Interleukin-6 -572 C>G and -174 G>C Polymorphisms and Hypertension: A Meta-analysis of Case-control Studies
H Ma, G Sun, W Wang, Y Zhou, D Liu, Y Tong, Z Lu |
Medicine | 2016 |
The impact of IL-6 and IL-28B gene polymorphisms on treatment outcome of chronic hepatitis C infection among intravenous drug users in Croatia
Z Bogdanović, I Marinović-Terzić, S Kuret, A Jerončić, N Bradarić, G Forempoher, O Polašek, Š Anđelinović, J Terzić |
PeerJ | 2016 |
Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms
JE Nelson, P Handa, B Aouizerat, L Wilson, LA Vemulakonda, MM Yeh, KV Kowdley |
Alimentary Pharmacology & Therapeutics | 2016 |
Ancestry informative markers and selected single nucleotide polymorphisms in immunoregulatory genes on preterm labor and preterm premature rupture of membranes: a case control study
BR de Ramos, ND Mendes, AA Tanikawa, MA Amador, NP Santos, SE Santos, EC Castelli, SS Witkin, MG da Silva |
BMC pregnancy and childbirth | 2016 |
Effect of interleukin 6 –174G>C gene polymorphism on opioid requirements after total hip replacement
M Białecka, A Jurewicz, A Machoy-Mokrzyńska, M Kurzawski, K Leźnicka, V Dziedziejko, K Safranow, M Droździk, A Bohatyrewicz |
Journal of Anesthesia | 2016 |
Interleukin-6 promoter polymorphism interacts with pain and life stress influencing depression phenotypes
D Kovacs, N Eszlari, P Petschner, D Pap, S Vas, P Kovacs, X Gonda, G Bagdy, G Juhasz |
Journal of Neural Transmission | 2016 |
Effect of Promoter Polymorphisms on Cytokine Concentration in Preterm Breast Milk and Subsequent Infant Outcomes
KL Baumgartel, MW Groer, SM Cohen, D Ren, DL Spatz, YP Conley |
Journal of Human Lactation | 2016 |
Functional Polymorphism in the Interleukin 6 (IL6) Gene with Respect to Depression Induced in the Course of Interferon-α and Ribavirin Treatment in Chronic Hepatitis Patients
D Frydecka, T Pawłowski, D Pawlak, K Małyszczak |
Archivum Immunologiae et Therapiae Experimentalis | 2016 |
Genetic Variant in ACVR2B Is Associated with Lean Mass:
YC Klimentidis, JW Bea, P Thompson, WT Klimecki, C Hu, G Wu, JS Nicholas, KK Ryckman, Z Chen |
Medicine and Science in Sports and Exercise | 2016 |
Impact of TNF-α (rs1800629) and IL-6 (rs1800795) Polymorphisms on Cognitive Impairment in Asian Breast Cancer Patients
J Chae, T Ng, HL Yeo, M Shwe, YX Gan, HK Ho, A Chan, J Spencer |
PloS one | 2016 |
Precision assessment of heterogeneity of lymphedema phenotype, genotypes and risk prediction
MR Fu, YP Conley, D Axelrod, AA Guth, G Yu, J Fletcher, D Zagzag |
The Breast | 2016 |
The -174G/C Interleukin-6 Gene Promoter Polymorphism as a Genetic Marker of Differences in Therapeutic Response to Methotrexate and Leflunomide in Rheumatoid Arthritis
AJ Ruiz-Padilla, JI Gamez-Nava, AM Saldaña-Cruz, JD Murillo-Vazquez, ML Vazquez-Villegas, SA Zavaleta-Muñiz, BT Martín-Márquez, JM Ponce-Guarneros, NA Jimenez, A Flores-Chavez, F Sandoval-Garcia, JC Vasquez-Jimenez, EG Cardona-Muñoz, SE Totsuka-Sutto, L Gonzalez-Lopez |
BioMed Research International | 2016 |
Promoter Polymorphism (-174, G/C) of Interleukin-6 and Arterial Thromboembolic Events: A Meta-Analysis
SK Kim, JH Chung, OY Kwon |
Medical science monitor : international medical journal of experimental and clinical research | 2016 |
Association between the interleukin-6 genetic polymorphism 174 G/C and thrombosis disorder risk: Meta-analysis of 10,549 cases and 19,316 controls
H Ren, Y Zhang, Y Yao, T Guo, H Wang, H Mei, Y Hu |
Medicine | 2016 |
Circulating interleukin-6 and rheumatoid arthritis: A Mendelian randomization meta-analysis
B Li, Y Xiao, D Xing, X Ma, J Liu |
Medicine | 2016 |
Genetic polymorphisms of interleukin 6 and interleukin 10 in Egyptian patients with systemic lupus eythematosus
RM Talaat, SA Alrefaey, IH Bassyouni, ME Ashour, AA Raouf |
Lupus | 2016 |
Evaluation of cytokine genetic polymorphisms in adult patients with common variable immunodeficiency: A single-center study
D Perovic, V Perovic, V Pravica, B Bonaci-Nikolic, R Mijanovic, V Bunjevacki |
Immunology Letters | 2016 |
The interleukin 6 c.-174 CC genotype is a predictor for new cardiovascular events in patients with coronary heart disease within three years follow-up
S Reichert, A Schlitt, AC Benten, B Hofmann, HG Schaller, S Schulz |
Cytokine | 2016 |
Cytokine gene polymorphism [tumor necrosis factor-alpha (–308), IL-10 (–1082), IL-6 (–174), IL-17F, 1RaVNTR] in pediatric patients with primary immune thrombocytopenia and response to different treatment modalities:
GM Mokhtar, NM El-beblawy, AA Adly, NS Elbarbary, TM Kamal, EM Hasan |
Blood Coagulation & Fibrinolysis | 2016 |
Interleukin-6-174G > C (rs1800795) polymorphism distribution and its association with rheumatoid arthritis: A case-control study and meta-analysis
SA Dar, S Haque, RK Mandal, T Singh, M Wahid, A Jawed, AK Panda, N Akhter, M Lohani, MY Areeshi, G Rai, S Datt, SN Bhattacharya, VG Ramachandran, S Das |
Autoimmunity | 2016 |
A study of TNF-α, TGF-β, IL-10, IL-6, and IFN-γ gene polymorphisms in patients with depression
S Mihailova, E Ivanova-Genova, T Lukanov, V Stoyanova, V Milanova, E Naumova |
Journal of Neuroimmunology | 2016 |
Modulators of the extracellular matrix and risk of anterior cruciate ligament ruptures
M Rahim, S Mannion, B Klug, H Hobbs, W der Merwe, M Posthumus, M Collins, AV September |
Journal of Science and Medicine in Sport | 2016 |
Cytokine polymorphisms in sickle cell disease and the relationship with cytokine expression
SC Gilli, FV Pericole, BD Benites, EÂ Sippert, LM Castilho, M Addas-Carvalho, ST Saad |
Experimental Hematology | 2016 |
The impact of the IL-1β, IL-1Ra, IL-2, IL-6 and IL-10 gene polymorphisms on the development of Behcet's disease and their association with the phenotype
S Barış, Ö Akyürek, A Dursun, M Akyol |
Medicina Clínica | 2016 |
Association of IL1Β (-511 A/C) and IL6 (-174 G > C) polymorphisms with higher disease activity and clinical pattern of psoriatic arthritis
N Cubino, C Montilla, R Usategui-Martín, C Cieza-Borrela, T Carranco, I Calero-Paniagua, A Quesada, JD Cañete, R Queiro, MD Sánchez, C Hidalgo, O Martínez, JD Pino-Montes, A Díaz-Álvarez, R González-Sarmiento |
Clinical Rheumatology | 2016 |
Association study of inflammatory genes with rheumatic heart disease in North Indian population: A multi-analytical approach
U Gupta, SS Mir, N Garg, SK Agarwal, S Pande, B Mittal |
Immunology Letters | 2016 |
IL-6 −174G/C polymorphism in obese adolescents with nonalcoholic fatty liver disease and its relation to metabolic and biochemical markers:
ME Zaki, HK Nazif, W Kandeel, HA El-Malt, Y El-Hossary, RM El-Sherbini, K Amr |
Middle East Journal of Medical Genetics | 2016 |
Association between interleukin-6 (G174C and C572G) promoter gene polymorphisms and risk of ischemic stroke in North Indian population: a case-control study
P Kumar, A Kumar, R Sagar, S Misra, M Faruq, V Suroliya, S Vivekanandhan, AK Srivastava, K Prasad |
Neurological Research | 2016 |
Biologic therapies in systemic juvenile idiopathic arthritis
ED Batu |
Expert Opinion on Orphan Drugs | 2016 |
Role of Helicobacter pylori and interleukin 6 -174 gene polymorphism in dyslipidemia: a case–control study
VM Pohjanen, OP Koivurova, SE Niemelä, RA Karttunen, TJ Karttunen |
BMJ Open | 2016 |
Low-grade inflammation markers in children and adolescents: Influence of anthropometric characteristics and CRP and IL6 polymorphisms
PF Todendi, LG Possuelo, EI Klinger, CP Reuter, MS Burgos, DJ Moura, M Fiegenbaum, AR de Valim |
Cytokine | 2016 |
Association of interleukin-6 methylation in leukocyte DNA with serum level and the risk of ischemic heart disease
Q Yang, Y Zhao, Z Zhang, J Chen |
Scandinavian Journal of Clinical & Laboratory Investigation | 2016 |
Association of tumour necrosis factor-alpha G/A -238 and G/A -308 single nucleotide polymorphisms with juvenile idiopathic arthritis
M Maddah, S Harsini, V Ziaee, MH Moradinejad, A Rezaei, S Zoghi, M Sadr, Y Aghighi, N Rezaei |
International Journal of Immunogenetics | 2016 |
Association of IL-6 Promoter and Receptor Polymorphisms with Multiple Myeloma Risk: A Systematic Review and Meta-Analysis
Y Li, Z Du, X Wang, G Wang, W Li |
Genetic Testing and Molecular Biomarkers | 2016 |
Association of Gene Polymorphisms in Interleukin 6 in Infantile Bronchial Asthma
E Babusikova, J Jurecekova, M Jesenak, A Evinova |
Archivos de Bronconeumología (English Edition) | 2016 |
Analysis of IL-10 and IL-6 Gene Polymorphisms and Their Serum Levels in Patients with Brucellosis: A Case Control Study
S Kazemi, M Saidijam, SH Hashemi, M Karami, A Vaisi-Raygani, MY Alikhani |
Immunological Investigations | 2016 |
Functional polymorphisms in the IL6 gene promoter and the risk of urinary bladder cancer in India
KA Gautam, T Muktanand, SN Sankhwar, A Goel, PL Sankhwar, S Rajender |
Cytokine | 2016 |
Increased expression of interleukin-6 (IL-6) gene transcript in relation to IL-6 promoter hypomethylation in gingival tissue from patients with chronic periodontitis
T Kobayashi, K Ishida, H Yoshie |
Archives of Oral Biology | 2016 |
Promoter Variation and Expression Levels of Inflammatory Genes IL1A, IL1B, IL6 and TNF in Blood of Spinocerebellar Ataxia Type 3 (SCA3) Patients
M Raposo, C Bettencourt, A Ramos, N Kazachkova, J Vasconcelos, T Kay, J Bruges-Armas, M Lima |
NeuroMolecular Medicine | 2016 |
Complete physical mapping of IL6 reveals a new marker associated with chronic periodontitis
SB Farhat, CM de Souza, AP Braosi, SH Kim, VA Tramontina, V Papalexiou, M Olandoski, MT Mira, SM Luczyszyn, PC Trevilatto |
Journal of Periodontal Research | 2016 |
IL6-174G > C genetic polymorphism influences antidepressant treatment outcome
S Carvalho, M Santos, L Lima, J Mota-Pereira, P Pimentel, D Maia, D Correia, S Gomes, A Cruz, R Medeiros |
Nordic Journal of Psychiatry | 2016 |
Interleukin 6 SNP rs1800797 associates with the risk of adult-onset asthma
TK Lajunen, JJ Jaakkola, MS Jaakkola |
Genes and Immunity | 2016 |
Polymorphisms of Cytokine Genes and Polycystic Ovary Syndrome: A Review
JB de Alencar, HV Alves, LN Elpidio, JE Visentainer, AM Sell |
Metabolic Syndrome and Related Disorders | 2016 |
Potential Effects of Interleukins on the Pathogenesis of Systemic Onset Juvenile Idiopathic Arthritis
LY Xu, WM Zhang, M Xia, LF Cao |
Pediatrics & Neonatology | 2016 |
The effects of IL-1A and IL-6 genes polymorphisms on gene expressions, hormonal and biochemical parameters in polycystic ovary syndrome
B Eser, MI Taskin, AA Hismiogullari, H Aksit, AS Bodur |
Journal of Obstetrics & Gynaecology | 2016 |
Polymorphisms of the interleukin 6 gene and additional gene–gene interaction contribute to cervical cancer susceptibility in Eastern Chinese women
X Pu, Z Gu, X Wang |
Archives of Gynecology and Obstetrics | 2016 |
Effect of G(-174)C polymorphism in interleukin-6 gene on cardiovascular disease in type 2 diabetes patients
M Buraczynska, P Zukowski, B Drop, I Baranowicz-Gaszczyk, A Ksiazek |
Cytokine | 2016 |
Relationships between Common and Novel Interleukin-6 Gene Polymorphisms and Risk of Cervical Cancer: a Case-Control Study
S Zidi, M Stayoussef, BL Alsaleh, E Gazouani, A Mezlini, BH Ebrahim, B Yacoubi-Loueslati, WY Almawi |
Pathology & Oncology Research | 2016 |
Influence of IL-6, IL-8, and TGF-β1 gene polymorphisms on the risk of human papillomavirus-infection in women from Pernambuco, Brazil
SF de Júnior, MM Tavares, JL de Macedo, RS de Oliveira, SA Heráclio, MM Maia, PR de Souza, R Moura, S Crovella |
Memórias do Instituto Oswaldo Cruz | 2016 |
Association between interleukin 6 -174 G/C promoter gene polymorphism and runners' responses to the dietary ingestion of antioxidant supplementation based on pequi (Caryocar brasiliense Camb.) oil: a before-after study
AL Miranda-Vilela, IF Ribeiro, CK Grisolia |
Genetics and molecular biology | 2016 |
Polymorphisms of α1-antitrypsin and Interleukin-6 genes and the progression of hepatic cirrhosis in patients with a hepatitis C virus infection
T Motawi, OG Shaker, RM Hussein, M Houssen |
Balkan Journal of Medical Genetics | 2016 |
The role of polymorphism of interleukin 2, 10, 13 and TNF-α genes in cutaneous T-cell lymphoma pathogenesis
B Nedoszytko, B Olszewska, J Roszkiewicz, J Glen, M Zabłotna, H Ługowska-Umer, R Nowicki, M Sokołowska-Wojdyło |
POSTEP DERM ALERGOL | 2016 |
Assessment of the −174G/C (rs1800795) and −572G/C (rs1800796) Interleukin 6 Gene Polymorphisms in Egyptian Patients with Rheumatoid Arthritis
K Amr, R El-Awady, H Raslan |
Open Access Macedonian Journal of Medical Sciences | 2016 |
Relationship between Interleukin-6 (-174G/C and -572C/G) Promoter Gene Polymorphisms and Risk of Intracerebral Hemorrhage: A Meta-Analysis
P Kumar, S Misra, AK Yadav, A Kumar, M Sriwastva, K Prasad |
Pulse (Basel, Switzerland) | 2016 |
TNF-α −308 polymorphisms and male infertility risk: A meta-analysis and systematic review
T Mostafa, M Taymour |
Journal of Advanced Research | 2016 |
Role of Helicobacter pylori and interleukin 6 -174 gene polymorphism in dyslipidemia: a case–control study
VM Pohjanen, OP Koivurova, SE Niemelä, RA Karttunen, TJ Karttunen |
BMJ Open | 2016 |
Correlation of interleukin-6-174 GC and interleukin-6-572 GC gene polymorphisms with periodontal disease in an Iranian population
Bahareh Nazemi Salman, Surena Vahabi, Alireza Biglari, Simindokht Salavitabar, Maryam Hassani Doabsari |
Dental Research Journal | 2016 |
Interleukin 6 SNP rs1800797 associates with the risk of adult-onset asthma.
Lajunen TK, Jaakkola JJ, Jaakkola MS |
Genes and Immunity | 2016 |
Association of IL1Β (-511 A/C) and IL6 (-174 G > C) polymorphisms with higher disease activity and clinical pattern of psoriatic arthritis.
Cubino N, Montilla C, Usategui-Martín R, Cieza-Borrela C, Carranco T, Calero-Paniagua I, Quesada A, Cañete JD, Queiro R, Sánchez MD, Hidalgo C, Martínez O, Del Pino-Montes J, Díaz-Álvarez A, González-Sarmiento R |
Clinical Rheumatology | 2016 |
Relationships between Common and Novel Interleukin-6 Gene Polymorphisms and Risk of Cervical Cancer: a Case-Control Study.
Zidi S, Stayoussef M, Alsaleh BL, Gazouani E, Mezlini A, Ebrahim BH, Yacoubi-Loueslati B, Almawi WY |
Pathology oncology research : POR | 2016 |
Promoter Variation and Expression Levels of Inflammatory Genes IL1A, IL1B, IL6 and TNF in Blood of Spinocerebellar Ataxia Type 3 (SCA3) Patients.
Raposo M, Bettencourt C, Ramos A, Kazachkova N, Vasconcelos J, Kay T, Bruges-Armas J, Lima M |
NeuroMolecular Medicine | 2016 |
Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation
A Varelias, KH Gartlan, E Kreijveld, SD Olver, M Lor, RD Kuns, KE Lineburg, BE Teal, NC Raffelt, M Cheong, KA Alexander, M Koyama, KA Markey, E Sturgeon, J Leach, P Reddy, GA Kennedy, GA Yanik, BR Blazar, SK Tey, AD Clouston, KP MacDonald, KR Cooke, GR Hill |
Blood | 2015 |
IL-6 as a keystone cytokine in health and disease
CA Hunter, SA Jones |
Nature Immunology | 2015 |
Genetic variant of Interleukin-18 gene is associated with the Frailty Index in the English Longitudinal Study of Ageing
K Mekli, A Marshall, J Nazroo, B Vanhoutte, N Pendleton |
Age and Ageing | 2015 |
Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)
DJ Raiten, FA Ashour, AC Ross, SN Meydani, HD Dawson, CB Stephensen, BJ Brabin, PS Suchdev, B Ommen |
The Journal of nutrition | 2015 |
Inflammaging decreases adaptive and innate immune responses in mice and humans
D Frasca, BB Blomberg |
Biogerontology | 2015 |
Therapeutic Potential of Interferon-γ and Its Antagonists in Autoinflammation: Lessons from Murine Models of Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome
A Avau, P Matthys |
Pharmaceuticals (Basel, Switzerland) | 2015 |
IL-6 polymorphism in non-small cell lung cancer: a prognostic value?
M Gomes, A Coelho, A Araújo, A Azevedo, AL Teixeira, R Catarino, R Medeiros |
Tumor Biology | 2015 |
The Roles of Post-translational Modifications in the Context of Protein Interaction Networks
G Duan, D Walther, P Radivojac |
PLoS computational biology | 2015 |
Radon Exposure, IL-6 Promoter Variants, and Lung Squamous Cell Carcinoma in Former Uranium Miners
S Leng, CL Thomas, AM Snider, MA Picchi, W Chen, DG Willis, TG Carr, J Krzeminski, D Desai, A Shantu, Y Lin, MR Jacobson, SA Belinsky |
Environmental Health Perspectives | 2015 |
The effect of gene polymorphisms on patient responses to rheumatoid arthritis therapy
M Tarnowski, A Paradowska-Gorycka, E Dąbrowska-Zamojcin, M Czerewaty, S Słuczanowska-Głąbowska, A Pawlik |
Expert Opinion on Drug Metabolism & Toxicology | 2015 |
CD38 and Interleukin 6 Gene Polymorphism in Egyptians with Diffuse Large B-Cell Lymphoma (DLBCL)
RM Talaat, AM Abdel-Aziz, EA El-Maadawy, N Abdel-Bary |
Immunological Investigations | 2015 |
Identification of a potential proinflammatory genetic profile influencing carotid plaque vulnerability
F Biscetti, G Straface, G Bertoletti, C Vincenzoni, F Snider, V Arena, R Landolfi, A Flex |
Journal of Vascular Surgery | 2015 |
Risk model incorporating donor IL6 and IFNG genotype and gastrointestinal GVHD can discriminate patients at high risk of steroid refractory acute GVHD
N Alam, W Xu, EG Atenafu, J Uhm, M Seftel, V Gupta, J Kuruvilla, JH Lipton, HA Messner, DD Kim |
Bone Marrow Transplantation | 2015 |
In vitro Production of IL-6 and IFN-γ is Influenced by Dietary Variables and Predicts Upper Respiratory Tract Infection Incidence and Severity Respectively in Young Adults
H Meng, Y Lee, Z Ba, JA Fleming, EJ Furumoto, RF Roberts, PM Kris-Etherton, CJ Rogers |
Frontiers in immunology | 2015 |
Predictive genetic markers of coagulation, inflammation and apoptosis in Perthes disease—Serbian experience
S Srzentić, G Nikčević, D Spasovski, Z Baščarević, Z Živković, Z Terzic-Šupić, D Matanović, V Djordjević, S Pavlović, V Spasovski |
European Journal of Pediatrics | 2015 |
Association of TNF-alpha, IL-6 and IL-1beta gene polymorphisms with polycystic ovary syndrome: a meta-analysis
R Guo, Y Zheng, J Yang, N Zheng |
BMC genetics | 2015 |
Human sickness behavior: Ultimate and proximate explanations: Human Sickness Behavior
EC Shattuck, MP Muehlenbein |
American Journal of Physical Anthropology | 2015 |
Association of IL-6 Polymorphism -174G/C and Metabolic Syndrome in Hypertensive Patients
AA Teixeira, BM Quinto, MA Dalboni, CJ de Rodrigues, MC Batista |
BioMed Research International | 2015 |
Interleukin-1β and interleukin-6 gene polymorphisms are associated with manifestations of sickle cell anemia
P Vicari, SA Adegoke, DR Mazzotti, RD Cançado, MA Nogutti, MS Figueiredo |
Blood Cells, Molecules, and Diseases | 2015 |
Association between IL-6-174G/C Polymorphism and the Risk of Sepsis and Mortality: A Systematic Review and Meta-Analysis
J Gao, A Zhang, W Pan, C Yue, L Zeng, W Gu, J Jiang, W Alazawi |
PloS one | 2015 |
Urinary Proteins, Vitamin D and Genetic Polymorphisms as Risk Factors for Febrile Urinary Tract Infection and Relation with Bacteremia: A Case Control Study
WE van der Starre, C Nieuwkoop, U Thomson, MS Zijderveld-Voshart, JP Koopman, TJ van der Reijden, JT van Dissel, E de Vosse, PG de Frutos |
PloS one | 2015 |
Interleukin and growth factor gene variants and risk of carpal tunnel syndrome
MC Burger, H Wet, M Collins |
Gene | 2015 |
Role of IL-6 −174(G/C) promoter polymorphism in the etiology of early-onset preeclampsia
S Sowmya, A Ramaiah, P Nallari, A Jyothy, A Venkateshwari |
Inflammation Research | 2015 |
Current understanding of the pathophysiology of systemic juvenile idiopathic arthritis (sJIA) and target-directed therapeutic approaches
N Bruck, A Schnabel, CM Hedrich |
Clinical Immunology | 2015 |
Lipid subclasses profiles and oxidative stress in aggressive periodontitis before and after treatment
L Nibali, M Rizzo, GL Volti, F D'Aiuto, RV Giglio, I Barbagallo, G Pelekos, N Donos |
Journal of Periodontal Research | 2015 |
Genetic association of key Th1/Th2 pathway candidate genes, IRF2, IL6, IFNGR2, STAT4 and IL4RA, with atopic asthma in the Indian population
A Kumar, S Das, A Agrawal, I Mukhopadhyay, B Ghosh |
Journal of Human Genetics | 2015 |
Exceptional longevity and muscle and fitness related genotypes: a functional in vitro analysis and case-control association replication study with SNPs THRH rs7832552, IL6 rs1800795, and ACSL1 rs6552828
N Fuku, Z He, F Sanchis-Gomar, H Pareja-Galeano, Y Tian, Y Arai, Y Abe, H Murakami, M Miyachi, H Zempo, H Naito, T Yvert, Z Verde, L Venturini, C Fiuza-Luces, A Santos-Lozano, G Rodriguez-Romo, G Ricevuti, N Hirose, E Emanuele, N Garatachea, A Lucia |
Frontiers in aging neuroscience | 2015 |
Predicting survival using clinical risk scores and non-HLA immunogenetics
Y Balavarca, K Pearce, J Norden, M Collin, G Jackson, E Holler, R Dressel, HJ Kolb, H Greinix, G Socie, A Toubert, V Rocha, E Gluckman, I Hromadnikova, P Sedlacek, D Wolff, U Holtick, A Dickinson, H Bickeböller |
Bone Marrow Transplantation | 2015 |
Genetic polymorphisms of interleukin-6 gene and susceptibility to coronary artery disease in Chinese population: Evidence based on 4582 subjects
SL Liu, YW Yin, QQ Sun, AM Hu, SJ Zhang |
Human Immunology | 2015 |
The -308 TNFα and the -174 IL-6 promoter polymorphisms associate with effective anti-TNFα treatment in seronegative spondyloarthritis
M Fabris, L Quartuccio, C Fabro, S Sacco, S Lombardi, R Ramonda, D Biasi, D Punzi, S Adami, I Olivieri, F Curcio, SD Vita |
The Pharmacogenomics Journal | 2015 |
Interleukin-18 promoter -607 C/A and -137 G/C polymorphisms and susceptibility to type 1 diabetes: A meta-analysis
YH Lee, JH Kim, GG Song |
Human Immunology | 2015 |
Clinical immunology Neonatal infections in Saudi Arabia: Association with cytokine gene polymorphisms
G Allam, AA Alsulaimani, AK Alzaharani, A Nasr |
CENT EUR J IMMUNOL | 2015 |
Association between Interleukin-6 (G174C and G572C) promoter gene polymorphisms and risk of ischaemic stroke: A meta-analysis
P Kumar, AK Yadav, A Kumar, R Sagar, AK Pandit, K Prasad |
Annals of Neurosciences | 2015 |
Proinflammatory genotype is associated with the frailty phenotype in the English Longitudinal Study of Ageing
K Mekli, JY Nazroo, AD Marshall, M Kumari, N Pendleton |
Aging clinical and experimental research | 2015 |
Immunogenetics of juvenile idiopathic arthritis: A comprehensive review
AO Hersh, S Prahalad |
Journal of Autoimmunity | 2015 |
Pharmacogenetic Study on the Impact of Rivastigmine Concerning Genetic Variants of A2M and IL-6 Genes on Iranian Alzheimer’s Patients
M Zamani, M Mohammadi, H Zamani, A Tavasoli |
Molecular Neurobiology | 2015 |
Less Frequent and Less Severe Flu-Like Syndrome in Interferon Beta-1a Treated Multiple Sclerosis Patients with at Least One Allele Bearing the G>C Polymorphism at Position -174 of the IL-6 Promoter Gene
D Bertoli, F Serana, A Sottini, C Cordioli, D Maimone, MP Amato, D Centonze, C Florio, E Puma, R Capra, L Imberti, RS Klein |
PloS one | 2015 |
Influence Of Promoter Polymorphisms Of The Tnf-α (-308g/A) And IL-6 (-174g/C) Genes On Therapeutic Response To Etanercept In Rheumatoid Arthritis
I Jančić, M Šefik-Bukilica, S Živojinović, N Damjanov, V Spasovski, N Kotur, K Klaassen, S Pavlović, B Bufan, N Arsenović-Ranin |
Journal of Medical Biochemistry | 2015 |
Association study of interleukin-1 family and interleukin-6 gene single nucleotide polymorphisms in recurrent aphthous stomatitis
S Najafi, H Yousefi, M Mohammadzadeh, AZ Bidoki, IF Moqadam, E Farhadi, AA Amirzargar, N Rezaei |
International Journal of Immunogenetics | 2015 |
Genetic Polymorphism and Messenger Ribonucleic Acid Concentrations of TNFα and TGFβ Genes in Patients with Chronic Lower Limb Infections
M Zagozda, A Sarnecka, Z Staszczak, H Gałkowska, P Andziak, WL Olszewski, M Durlik |
Surgical Infections | 2015 |
Luteolin 8-C-β-fucopyranoside downregulates IL-6 expression by inhibiting MAPKs and the NF-κB signaling pathway in human monocytic cells
YS Lee, MS Kim, DH Lee, TH Kwon, HH Song, SR Oh, DY Yoon |
Pharmacological Reports | 2015 |
Association between IL-6 −174 G/C, IL-6 −634 G/C, and IFN-γ +874 A/T polymorphisms and susceptibility to recurrent pregnancy loss: a meta-analysis
YH Lee, SJ Choi, JD Ji |
Journal of Assisted Reproduction and Genetics | 2015 |
Contribution of IL6 −174 G>C and IL1B +3954 C>T polymorphisms to congenital infection with Toxoplasma gondii
W Wujcicka, Z Gaj, J Wilczyński, D Nowakowska |
European Journal of Clinical Microbiology & Infectious Diseases | 2015 |
Glucocorticoid pharmacogenetics in pediatric idiopathic nephrotic syndrome
E Cuzzoni, SD Iudicibus, R Franca, G Stocco, M Lucafò, M Pelin, D Favretto, A Pasini, G Montini, G Decorti |
Pharmacogenomics | 2015 |
-572 G/C single nucleotide polymorphism of interleukin-6 and sepsis predisposition in chronic renal disease
A Panayides, A Ioakeimidou, V Karamouzos, N Antonakos, I Koutelidakis, G Giannikopoulos, K Makaritsis, N Voloudakis, K Toutouzas, N Rovina, M Bristianou, G Damoraki, C Routsi, EJ Giamarellos-Bourboulis |
European Journal of Clinical Microbiology & Infectious Diseases | 2015 |
Association of TNF-α -308G/A and IL-6 -174G/C gene polymorphism with pneumonia-induced sepsis
B Feng, Z Mao, K Pang, S Zhang, L Li |
Journal of Critical Care | 2015 |
TNF-α - 308 polymorphisms and male infertility risk: A meta-analysis and systematic review
T Mostafa, M Taymour |
Journal of Advanced Research | 2015 |
Association of interleukin-6 gene polymorphism (rs1800796) with severity and functional status of osteoarthritis in elderly individuals
MT Fernandes, KB Fernandes, AS Marquez, IM Cólus, MF Souza, JP Santos, RC Poli-Frederico |
Cytokine | 2015 |
Gene polymorphisms in periodontitis. Overview
V Dosseva-Panova, A Mlachkova, C Popova |
Biotechnology & Biotechnological Equipment | 2015 |
Aggressive Periodontitis: microbes and host response, who to blame?
L Nibali |
Virulence | 2015 |
Effect of interleukin-6 polymorphism on fracture risk
Chuangli Wang, Jianfei Ge, Shanjun Ni |
International journal of clinical and experimental medicine | 2015 |
Nutritional Intervention in Metabolic Syndrome
H Takahashi, L Roma, M Silva |
Nutritional Intervention in Metabolic Syndrome | 2015 |
Association of gene polymorphism with serum levels of inflammatory and angiogenic factors in Pakistani patients with age-related macular degeneration
Fareeha Ambreen, Muhammad Ismail, Irfan Zia Qureshi |
Molecular vision | 2015 |
Analysis of a Functional IL-6 Gene Polymorphism in HLAB27 Associated and Intermediate Uveitis Gives New Insight in Disease Pathogenesis and Commonality with Other Autoimmune Diseases
L Ewald, LW Beate, S Stephanie, R Wilfried, ES Yosuf |
Journal of Immunology Research | 2015 |
Association of Plasma Heat Shock Protein 70, Interleukin 6, and Creatine Kinase Concentrations in a Healthy, Young Adult Population
C Contreras-Sesvold, BD Revenis, FG OConnor, PA Deuster |
Journal of Biomarkers | 2015 |
Are Immune Modulating Single Nucleotide Polymorphisms Associated with Necrotizing Enterocolitis?
AL Franklin, M Said, CD Cappiello, H Gordish-Dressman, Z Tatari-Calderone, S Vukmanovic, K Rais-Bahrami, NL Luban, JM Devaney, AD Sandler |
Scientific Reports | 2015 |
Genetic polymorphism directs IL-6 expression in fibroblasts but not selected other cell types
EH Noss, HN Nguyen, SK Chang, GF Watts, MB Brenner |
Proceedings of the National Academy of Sciences | 2015 |
Genetic Associations of Interleukin-related Genes with Graves’ Ophthalmopathy: a Systematic Review and Meta-analysis
KH Wong, SS Rong, KK Chong, AL Young, CP Pang, LJ Chen |
Scientific Reports | 2015 |
Interleukin-6 promoter haplotypes are associated with etanercept response in patients with rheumatoid arthritis
H Schotte, H Schmidt, M Gaubitz, S Drynda, J Kekow, P Willeke, B Schlüter |
Clinical Rheumatology | 2015 |
The Evaluation of IL6 and ESR1 Gene Polymorphisms in Primary Dysmenorrhea
AZ Ozsoy, N Karakus, S Yigit, B Cakmak, MC Nacar, HY Dogru |
Immunological Investigations | 2015 |
Rhabdomyolysis After Out-of-Water Exercise in an Elite Adolescent Water Polo Player Carrying the IL-6 174C Allele Single-Nucleotide Polymorphism:
A Eliakim, SB Zaken, Y Meckel, C Yamin, N Dror, D Nemet |
Journal of Strength and Conditioning Research | 2015 |
The polymorphism of some genes of the immune response in patients with atopic dermatitis
YV Maksimova, EV Svechnikova, VN Maximov, KN Kolesnik, AV Aleshkina, EI Akinshina, OB Nemchaninova |
Klinicheskaya dermatologiya i venerologiya | 2015 |
Roles of interleukin (IL)-6 gene polymorphisms, serum IL-6 levels, and treatment in obstructive sleep apnea: a meta-analysis
A Zhong, X Xiong, M Shi, H Xu |
Sleep and Breathing | 2015 |
Relationships between cytokine (IL-6 and TGF-β 1 ) gene polymorphisms and chromosomal damage in hospital workers
A Santovito, P Cervella, M Chiarizio, G Meschiati, M Delsoglio, E Manitta, G Picco, M Delpero |
Journal of Immunotoxicology | 2015 |
Handbook of Juvenile Idiopathic Arthritis
A Ravelli |
Handbook of Juvenile Idiopathic Arthritis | 2015 |
Association between polymorphism of interleukin-6 in the region -174G/C and tinnitus in the elderly with a history of occupational noise exposure
MY Doi, AC Dias, RC Poly-Frederico, MG Maria, MN Oliveira, LL Marchiori |
Noise & health | 2015 |
Interleukin-6 gene -174G/C polymorphism and bronchial asthma risk: a meta-analysis
Fangwei Li, Xinming Xie, Shaojun Li, Rui Ke, Bo Zhu, Lan Yang, Manxiang Li |
International journal of clinical and experimental medicine | 2015 |
Association of interleukin-6-572C/G gene polymorphism and serum or cerebrospinal fluid interleukin-6 level with enterovirus 71 encephalitis in Chinese Han patients with hand, foot, and mouth disease.
Yuan A, Li J, Liu P, Chen Z, Hou M, Wang J, Han Z |
Inflammation | 2015 |
Interleukin-6 promoter haplotypes are associated with etanercept response in patients with rheumatoid arthritis.
Schotte H, Schmidt H, Gaubitz M, Drynda S, Kekow J, Willeke P, Schlüter B |
Clinical Rheumatology | 2015 |
Roles of interleukin (IL)-6 gene polymorphisms, serum IL-6 levels, and treatment in obstructive sleep apnea: a meta-analysis.
Zhong A, Xiong X, Shi M, Xu H |
Sleep & breathing = Schlaf & Atmung | 2015 |
New Approaches for Studying Alcoholic Liver Disease
J Xu, X Liu, B Gao, M Karin, H Tsukamoto, D Brenner, T Kisseleva |
Current Pathobiology Reports | 2014 |
Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies
N JOHNS, BH Tan, M MACMILLAN, TS Solheim, JA Ross, VE Baracos, S DAMARAJU, KC Fearon |
Journal of Genetics | 2014 |
Interleukin 6 and Rheumatoid Arthritis
Y Yoshida, T Tanaka |
BioMed Research International | 2014 |
IL-6 in Inflammation, Immunity, and Disease
T Tanaka, M Narazaki, T Kishimoto |
Cold Spring Harbor perspectives in biology | 2014 |
The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?
KR Doty, MV Guillot-Sestier, T Town |
Brain Research | 2014 |
Genetic polymorphisms of cytokine genes in type 2 diabetes mellitus
M Banerjee, M Saxena |
World journal of diabetes | 2014 |
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression
GM Slavich, MR Irwin |
Psychological Bulletin | 2014 |
Gene of the month: Interleukin 6 (IL-6)
P Ataie-Kachoie, MH Pourgholami, DR Richardson, DL Morris |
Journal of clinical pathology | 2014 |
A Peripheral Circulating TH1 Cytokine Profile Is Inversely Associated with Prostate Cancer Risk in CLUE II
NA Bhavsar, JH Bream, AK Meeker, CG Drake, SB Peskoe, D Dabitao, AM de Marzo, WB Isaacs, EA Platz |
Cancer epidemiology, biomarkers & prevention | 2014 |
HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy
DC Fajgenbaum, F Rhee, CS Nabel |
Blood | 2014 |
Rheumatoid arthritis and genetic variations in cytokine genes: a population-based study in Kashmir Valley
S Shafia, Dilafroze, FA Sofi, R Rasool, S Javeed, ZA Shah |
Immunological Investigations | 2014 |
Investigation of relationship between IL-6 gene variants and hypertension in Turkish population
E Karaman, MU Kucuk, A Bayramoglu, SU Göçmen, S Ercan, HI Guler, Y Kucukkaya, S Erden |
Cytotechnology | 2014 |
The microbiome, parturition, and timing of birth: more questions than answers
AL Prince, KM Antony, DM Chu, KM Aagaard |
Journal of Reproductive Immunology | 2014 |
Variants in C-reactive protein and IL-6 genes and susceptibility to obstructive sleep apnea in children: a candidate-gene association study in European American and Southeast European populations
AG Kaditis, D Gozal, A Khalyfa, L Kheirandish-Gozal, OS Capdevila, K Gourgoulianis, EI Alexopoulos, K Chaidas, R Bhattacharjee, J Kim, P Rodopoulou, E Zintzaras |
Sleep Medicine | 2014 |
Neuroimmunological aberrations and cerebral asymmetry abnormalities in schizophrenia: select perspectives on pathogenesis
G Venkatasubramanian, M Debnath |
Clinical Psychopharmacology and Neuroscience | 2014 |
Relationship between Interleukin-6 gene polymorphism and hippocampal volume in antipsychotic-naïve schizophrenia: evidence for differential susceptibility?
SV Kalmady, G Venkatasubramanian, V Shivakumar, S Gautham, A Subramaniam, DA Jose, A Maitra, V Ravi, BN Gangadhar |
PloS one | 2014 |
Association between COX-2 rs 6681231 genotype and interleukin-6 in periodontal connective tissue. A pilot study
F Mesa, F O'Valle, M Rizzo, F Cappello, N Donos, M Parkar, N Chaudhary, F Carini, R Muñoz, L Nibali |
PloS one | 2014 |
-174G/C polymorphism in the interleukin-6 promoter is differently associated with prostate cancer incidence depending on race
S Mandal, F Abebe, J Chaudhary |
Genetics and molecular research : GMR | 2014 |
Relation between inflammatory cytokine levels in serum and bronchoalveolar lavage fluid and gene polymorphism in young adult patients with bronchiectasis
G Ayhan, D Tas, I Yilmaz, O Okutan, E Demirer, O Ayten, Z Kartaloglu |
Journal of Thoracic Disease | 2014 |
International Review of Neurobiology
JM Loftis, A Janowsky |
International review of neurobiology | 2014 |
Do Genetic Susceptibility, Toll-like Receptors, and Pathogen-associated Molecular Patterns Modulate the Effects of Wear?
EM Greenfield |
Clinical Orthopaedics and Related Research® | 2014 |
Modifying Effect of a Common Polymorphism in the Interleukin-6 Promoter on the Relationship between Long-Term Exposure to Traffic-Related Particulate Matter and Heart Rate Variability
M Adam, M Imboden, E Boes, E Schaffner, N Künzli, HC Phuleria, F Kronenberg, JM Gaspoz, D Carballo, N Probst-Hensch |
PloS one | 2014 |
Polymorphisms in the TNFA and IL6 Genes Represent Risk Factors for Autoimmune Thyroid Disease
C Durães, CS Moreira, I Alvelos, A Mendes, LR Santos, JC Machado, M Melo, C Esteves, C Neves, M Sobrinho-Simões, P Soares |
PloS one | 2014 |
Genetic polymorphisms and skin aging: the identification of population genotypic groups holds potential for personalized treatments
J Naval, V Alonso, MA Herranz |
Clinical, cosmetic and investigational dermatology | 2014 |
Association between interleukin-6 gene polymorphisms and rheumatoid arthritis in Chinese Han population: a case-control study and a meta-analysis
F Li, J Xu, J Zheng, J Sokolove, K Zhu, Y Zhang, H Sun, E Evangelou, Z Pan |
Scientific Reports | 2014 |
Evaluation of anakinra for the treatment of systemic juvenile idiopathic arthritis
SJ Vastert, JF Swart, NM Wulffraat |
Expert Opinion on Orphan Drugs | 2014 |
Association of Cytokines in Individuals Sensitive and Insensitive to Dust Mites in a Brazilian Population
MC da Caniatti, AA Marchioro, AL Guilherme, LT Tsuneto, LH Carvalho |
PloS one | 2014 |
Patients With Chronic Three-Vessel Disease in a 15-Year Follow-Up Study: Genetic and Non-Genetic Predictors of Survival
J Máchal, M Pávková-Goldbergová, O Hlinomaz, L Groch, A Vašků |
Medicine | 2014 |
Cytokine balance and cytokine-driven natural killer cell dysfunction in systemic juvenile idiopathic arthritis
A Avau, K Put, CH Wouters, P Matthys |
Cytokine & Growth Factor Reviews | 2014 |
A case-control study on proinflammatory genetic Polymorphisms on sudden sensorineural hearing loss: Polymorphisms on SSNHL
G Cadoni, E Gaetani, PM Picciotti, D Arzani, M Quarta, S Giannantonio, G Paludetti, S Boccia |
The Laryngoscope | 2014 |
The interleukin-6 and interleukin-1A gene promoter polymorphism is associated with the pathogenesis of acne vulgaris
S Younis, Q Javed |
Archives of Dermatological Research | 2014 |
Pathogenesis of adult-onset Still’s disease: new insights from the juvenile counterpart
Y Jamilloux, M Gerfaud-Valentin, F Martinon, A Belot, T Henry, P Sève |
Immunologic Research | 2014 |
Age-Related Macular Degeneration: Insights into Inflammatory Genes
R Cascella, M Ragazzo, C Strafella, F Missiroli, P Borgiani, F Angelucci, LT Marsella, A Cusumano, G Novelli, F Ricci, E Giardina |
Journal of Ophthalmology | 2014 |
Racial/ethnic disparities in inflammatory gene single-nucleotide polymorphisms as predictors of a high risk for symptom burden in patients with multiple myeloma 1 year after diagnosis: Inflammatory Gene SNPs Predict Symptoms
Q Shi, XS Wang, G Li, ND Shah, RZ Orlowski, LA Williams, TR Mendoza, CS Cleeland |
Cancer | 2014 |
Association of a Mutation in LACC1 With a Monogenic Form of Systemic Juvenile Idiopathic Arthritis: Monogenic Systemic Juvenile Idiopathic Arthritis
SM Wakil, DM Monies, M Abouelhoda, N Al-Tassan, H Al-Dusery, EA Naim, B Al-Younes, J Shinwari, FA Al-Mohanna, BF Meyer, S Al-Mayouf |
Arthritis & Rheumatology | 2014 |
The Role of Interleukin-6 and Interleukin-8 Gene Polymorphisms in Non-Alcoholic Steatohepatitis
M Cengiz, DG Yasar, MA Ergün, G Akyol, S Ozenirler |
Hepatitis Monthly | 2014 |
Relationship of the urine cortisol level with the performance status of patients with lung cancer: a retrospective study
K Suzuki, T Ichikawa, H Furuse, T Tsuda, K Tokui, Y Masaki, S Okazawa, K Kambara, M Inomata, T Yamada, T Miwa, S Matsui, T Kashii, H Taniguchi, R Hayashi, K Tobe |
Supportive Care in Cancer | 2014 |
Genetic polymorphism of interleukin-6 influences susceptibility to HBV-related hepatocellular carcinoma in a male Chinese Han population
S Tang, Y Yuan, Y He, D Pan, Y Zhang, Y Liu, Q Liu, Z Zhang, Z Liu |
Human Immunology | 2014 |
Polymorphisms of interleukin 6 and interleukin 10 in Egyptian people with Behcet's disease
RM Talaat, ME Ashour, IH Bassyouni, AA Raouf |
Immunobiology | 2014 |
Synergistic effect of anti and pro-inflammatory cytokine genes and their promoter polymorphism with ST-elevation of myocardial infarction
S Biswas, PK Ghoshal, N Mandal |
Gene | 2014 |
Association of IL-6−174G>C and −572C>G polymorphisms with risk of young ischemic stroke patients
X Yang, L Feng, C Li, Y Li |
Gene | 2014 |
Association of interleukin-6 polymorphisms with obesity and metabolic alterations in young Saudi population
KK Alharbi, R Syed, IA Khan |
Molecular Biology Reports | 2014 |
Interleukin-6 gene polymorphism, chronic stress and atherosclerosis
N Chumaeva, M Hintsanen, L Pulkki-Råback, M Jokela, M Juonala, T Lehtimäki, OT Raitakari, L Keltikangas-Järvinen |
Journal of Psychosomatic Research | 2014 |
IL6-174 G/C gene polymorphism and its relation to serum IL6 in Egyptian children with community-acquired pneumonia
HE Zidan, RM Elbehedy, SF Azab |
Cytokine | 2014 |
Association of NLRP3 and CARD8 genetic polymorphisms with juvenile idiopathic arthritis in a Taiwanese population
CA Yang, ST Huang, BL Chiang |
Scandinavian Journal of Rheumatology | 2014 |
Regulation of the Interleukin-6 gene expression during monocytic differentiation of HL-60 cells by chromatin remodeling and methylation
MK Poplutz, I Wessels, L Rink, P Uciechowski |
Immunobiology | 2014 |
Predictive Value of Selected Biomarkers, Polymorphisms, and Clinical Features for Oligoarticular Juvenile Idiopathic Arthritis-associated Uveitis
L Pelegrín, R Casaroli-Marano, J Antón, MC de Vicuña, N Molina-Prat, JI Aróstegui, J Yagüe, J Ríos, A Adán |
Ocular Immunology and Inflammation | 2014 |
Immunologic and psychologic parameters associated with geographic tongue
M Alikhani, N Khalighinejad, P Ghalaiani, MA Khaleghi, E Askari, M Gorsky |
Oral Surgery Oral Medicine Oral Pathology and Oral Radiology | 2014 |
Use of floss/interdental brushes is associated with lower risk for new cardiovascular events among patients with coronary heart disease
S Reichert, A Schlitt, V Beschow, A Lutze, S Lischewski, T Seifert, T Dudakliewa, R Gawe, K Werdan, B Hofmann, HG Schaller, S Schulz |
Journal of Periodontal Research | 2014 |
Association Between IL-6 -174G/C Polymorphism and Risk of Multiple Sclerosis: A Meta-Analysis
S Hu, Y Chen, XD Sun, FJ Li, QF Shu, XL Liu, SF Jiang |
Genetic Testing and Molecular Biomarkers | 2014 |
Association of Interleukin-6 −174 G>C Promoter Polymorphism with Increased Risk of Type 2 Diabetes Mellitus Patients with Diabetic Nephropathy in Turkey
M Karadeniz, M Erdogan, A Berdeli, C Yilmaz |
Genetic Testing and Molecular Biomarkers | 2014 |
Association of pregnancy outcome with cytokine gene polymorphisms in HEV infection during pregnancy: Cytokine Gene Polymorphisms and HEV Infection
SG Devi, A Kumar, P Kar, SA Husain, S Sharma |
Journal of Medical Virology | 2014 |
Functional FCGR3A 158 V/F and IL-6 −174 C/G polymorphisms predict response to biologic therapy in patients with rheumatoid arthritis: a meta-analysis
YH Lee, SC Bae, GG Song |
Rheumatology International | 2014 |
Role of IL6, IL12B and VDR gene polymorphisms in Plasmodium vivax malaria severity, parasitemia and gametocytemia levels in an Amazonian Brazilian population
VA Sortica, MG Cunha, MD Ohnishi, JM Souza, ÂK Ribeiro-dos-Santos, SE Santos, MH Hutz |
Cytokine | 2014 |
Increased serum interleukin-6 levels in early stages of psychosis: Associations with at-risk mental states and the severity of psychotic symptoms
A Stojanovic, L Martorell, I Montalvo, L Ortega, R Monseny, E Vilella, J Labad |
Psychoneuroendocrinology | 2014 |
Study of the cytokine polymorphisms in correlation to rejection and graft survival in renal allograft donors and recipients from a homogenous Saudi population
A Gaafar, A Iqniebi, A Sheereen, A Eldali, H Turpeinen, C Adra, KA Meshari, KA Hussein |
Transplant Immunology | 2014 |
Interleukin-6 G-174C gene polymorphism and susceptibility to upper respiratory tract infection among endurance athletes
F Zehsaz, N Farhangi, A Monfaredan |
Journal of Exercise Science & Fitness | 2014 |
Lack of association between −174G>C and −634C>G polymorphisms in interleukin-6 promoter region and lung cancer risk: a meta-analysis
F Jiao, D Xu, Q Li, G Liu, H Liu, T Ren |
Tumor Biology | 2014 |
Adult-onset Still's disease
M Gerfaud-Valentin, Y Jamilloux, J Iwaz, P Sève |
Autoimmunity Reviews | 2014 |
Update on research and clinical translation on specific clinical areas: From bench to bedside: How insight in immune pathogenesis can lead to precision medicine of severe juvenile idiopathic arthritis
S Vastert, B Prakken |
Best Practice & Research Clinical Rheumatology | 2014 |
Données actualisées sur la physiopathologie, les phénotypes et les traitements de la maladie de Still de l’adulte
M Gerfaud-Valentin, P Sève, A Hot, C Broussolle, Y Jamilloux |
La Revue de Médecine Interne | 2014 |
Interleukin-6 in renal disease and therapy
SA Jones, DJ Fraser, CA Fielding, GW Jones |
Nephrology Dialysis Transplantation | 2014 |
Interleukin-6(-174) Locus Polymorphism and Serum IL-6 Levels in Normal Tension Glaucoma
KH Lin, SC Feng, YC Shen, LC Wei, CY Liang, CJ Chang, YY Yang, CH Chiu, CY Wang |
Ophthalmic Genetics | 2014 |
Involvement of IL-6 and IL-1 receptor antagonist on intellectual disability
A Aureli, P Sebastiani, TD Beato, AE Marimpietri, A Graziani, E Sechi, SD Loreto |
Immunology Letters | 2014 |
Combined impact of hepatitis C virus genotype 1 and interleukin-6 and tumor necrosis factor-α polymorphisms on serum levels of pro-inflammatory cytokines in Brazilian HCV-infected patients
AM Tarragô, AG da Costa, JP Pimentel, ST Gomes, FB Freitas, P Lalwani, AR de Araújo, FS Victória, MB Victória, AC Vallinoto, A Sadahiro, A Teixeira-Carvalho, OA Martins-Filho, A Malheiro |
Human Immunology | 2014 |
Genetic Association of BSF2 Polymorphism and Susceptibility to Lung Cancer
H Wang, Z Liu |
Cell Biochemistry and Biophysics | 2014 |
Association between interleukin-6 polymorphism in the −174 G/C region and hearing loss in the elderly with a history of occupational noise exposure
MP Braga, SM Maciel, LL de Marchiori, RC Poli-Frederico |
Brazilian Journal of Otorhinolaryngology | 2014 |
Association of Interleukin-6-572C/G Gene Polymorphism and Serum or Cerebrospinal Fluid Interleukin-6 Level with Enterovirus 71 Encephalitis in Chinese Han Patients with Hand, Foot, and Mouth Disease
A Yuan, J Li, P Liu, Z Chen, M Hou, J Wang, Z Han |
Inflammation | 2014 |
Polymorphisms in the TNFA and IL6 Genes Represent Risk Factors for Autoimmune Thyroid Disease
C Durães, CS Moreira, I Alvelos, A Mendes, LR Santos, JC Machado, M Melo, C Esteves, C Neves, M Sobrinho-Simões, P Soares, AP Arez |
PloS one | 2014 |
Host genetic factors in American cutaneous leishmaniasis: a critical appraisal of studies conducted in an endemic area of Brazil
LC Castellucci, LF de Almeida, SE Jamieson, M Fakiola, EM de Carvalho, JM Blackwell |
Memórias do Instituto Oswaldo Cruz | 2014 |
Interleukin-6: the missing element of the neurocognitive deterioration in schizophrenia? The focus on genetic underpinnings, cognitive impairment and clinical manifestation
D Frydecka, B Misiak, E Pawlak-Adamska, L Karabon, A Tomkiewicz, P Sedlaczek, A Kiejna, JA Beszłej |
European Archives of Psychiatry and Clinical Neuroscience | 2014 |
Stratification Analysis and Case-control Study of Relationships between Interleukin-6 Gene Polymorphisms and Cervical Cancer Risk in a Chinese Population
WJ Shi, H Liu, D Wu, ZH Tang, YC Shen, L Guo |
Asian Pacific Journal of Cancer Prevention | 2014 |
IL6-174G/C polymorphism and fracture risk
Zhichang Zhang, Nengbin He, Tao Zhang |
International journal of clinical and experimental medicine | 2014 |
Interleukin-6 genotypes and serum levels in Chinese Hui population
Shu-Ping Gao, Shu Liang, Min Pan, Rong-Liang Sun, Chu Chen, Hong Luan, Min-Hui Jiang |
International journal of clinical and experimental medicine | 2014 |
Clinical relevance of IL-6 gene polymorphism in severely injured patients
Vasilije Jeremić, Tamara Alempijević, Srđan Mijatović, Ana Šijački, Sanja Dragašević, Sonja Pavlović, Biljana Miličić, Slobodan Krstić |
BOSNIAN J BASIC MED | 2014 |
Interleukin-6 and interleukin-10 gene polymorphisms and recurrent pregnancy loss in Romanian population
Camil L. Bohiltea, Viorica E. Radoi |
IRAN J REPROD MED | 2014 |
Clinical Implications of Tumor Necrosis Factor-Alpha, Interleukin-6 and Resistin in Coronary Artery Disease
Q Javed |
World Journal of Cardiovascular Diseases | 2014 |
Relationship between Interleukin-6 Gene Polymorphism and Hippocampal Volume in Antipsychotic-Naïve Schizophrenia: Evidence for Differential Susceptibility?
SV Kalmady, G Venkatasubramanian, V Shivakumar, S Gautham, A Subramaniam, DA Jose, A Maitra, V Ravi, BN Gangadhar, M Uddin |
PloS one | 2014 |
Modifying Effect of a Common Polymorphism in the Interleukin-6 Promoter on the Relationship between Long-Term Exposure to Traffic-Related Particulate Matter and Heart Rate Variability
M Adam, M Imboden, E Boes, E Schaffner, N Künzli, HC Phuleria, F Kronenberg, JM Gaspoz, D Carballo, N Probst-Hensch, RA Coulombe |
PloS one | 2014 |
Association between COX-2 rs 6681231 Genotype and Interleukin-6 in Periodontal Connective Tissue. A Pilot Study
F Mesa, F OValle, M Rizzo, F Cappello, N Donos, M Parkar, N Chaudhary, F Carini, R Muñoz, L Nibali, S Amar |
PloS one | 2014 |
Frequencies of interleukin-6, GST and progesterone receptor gene polymorphisms in postmenopausal women with low bone mineral density
KF Moura, M Haidar, C Bonduki, PC Feldner, I Silva, JM Soares, MJ Girao |
Sao Paulo Medical Journal | 2014 |
Association of interleukin-6 polymorphisms with obesity and metabolic alterations in young Saudi population.
Alharbi KK, Syed R, Khan IA |
Molecular Biology Reports | 2014 |
[Association of genetic polymorphisms in IL-6 and IL-1β gene with risk of lung cancer in female non-smokers].
Su M, Zhou B |
Zhongguo fei ai za zhi = Chinese journal of lung cancer | 2014 |
Lack of association between -174G>C and -634C>G polymorphisms in interleukin-6 promoter region and lung cancer risk: a meta-analysis.
Jiao F, Xu D, Li Q, Liu G, Liu H, Ren T |
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine | 2014 |
Functional FCGR3A 158 V/F and IL-6 -174 C/G polymorphisms predict response to biologic therapy in patients with rheumatoid arthritis: a meta-analysis.
Lee YH, Bae SC, Song GG |
Rheumatology International | 2014 |
[Association between interleukin-6 polymorphism in the -174 G/C region and hearing loss in the elderly with a history of occupational noise exposure].
Braga MP, Maciel SM, Marchiori LL, Poli-Frederico RC |
Brazilian Journal of Otorhinolaryngology | 2014 |
Frequencies of interleukin-6, GST and progesterone receptor gene polymorphisms in postmenopausal women with low bone mineral density: Frequência do polimorfismo da interleucina-6, GST, e dos receptores de progesterona em mulheres na pós-menopausa com baixa densidade mineral óssea
Moura KF, Haidar M, Bonduki C, Feldner PC Júnior, Silva I, Soares JM Júnior, Girão MJ |
2014 | |
Interleukin-6 polymorphisms: a useful genetic tool for inflammation research?
Steve Humphries, Patricia Woo |
Journal of Clinical Investigation | 2013 |
Imbalanced frequencies of Th17 and Treg cells in acute coronary syndromes are mediated by IL-6-STAT3 signaling
Y Ma, X Yuan, L Deng, W Xu, Y Zheng, C Yue, G Zhang, F Xie, YH Yang, MP Gantier, JP Liu, D Xu, L Shen |
PloS one | 2013 |
Genes for Elite Power and Sprint Performance: ACTN3 Leads the Way
N Eynon, ED Hanson, A Lucia, PJ Houweling, F Garton, KN North, DJ Bishop |
Sports Medicine | 2013 |
Cytokine gene polymorphism and graft-versus-host disease: a survey in Iranian bone marrow transplanted patients
MR Noori-Daloii, N Jalilian, P Izadi, M Sobhani, Z Rabii-Gilani, MS Yekaninejad |
Molecular Biology Reports | 2013 |
Association of IL-6 G-174C polymorphism with bone mineral density
Y Ni, H Li, Y Zhang, H Zhang, Y Pan, J Ma, L Wang |
Journal of Bone and Mineral Metabolism | 2013 |
Negative emotions predict elevated interleukin-6 in the United States but not in Japan
Y Miyamoto, JM Boylan, CL Coe, KB Curhan, CS Levine, HR Markus, J Park, S Kitayama, N Kawakami, M Karasawa, GD Love, CD Ryff |
Brain, Behavior, and Immunity | 2013 |
Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels
K Stone, E Woods, SM Szmania, OW Stephens, TK Garg, B Barlogie, JD Shaughnessy, B Hall, M Reddy, A Hoering, E Hansen, F Rhee |
PloS one | 2013 |
The role of non-HLA gene polymorphisms in graft-versus-host disease
A Takami |
International Journal of Hematology | 2013 |
Personalisierte Medizin bei Zytokin-gerichteten Therapien
F Behrens, M Köhm |
Zeitschrift für Rheumatologie | 2013 |
Allele frequency distributions of -174G/C polymorphism in regulatory region of interleukin 6 gene (IL6) in Russian and worldwide populations
SA Borinskaya, AS Gureev, AA Orlova, ED Sanina, AA Kim, F Gasemianrodsari, VI Shirmanov, OP Balanovsky, DV Rebrikov, AV Koshechkin, NK Yankovsky |
Russian Journal of Genetics | 2013 |
Systemic Inflammation Is Associated with Differential Gene Expression and Airway Neutrophilia in Asthma
J Fu, KJ Baines, LG Wood, PG Gibson |
OMICS: A Journal of Integrative Biology | 2013 |
IL-6-174 G>C and MMP-9-1562 C>T polymorphisms are associated with increased risk of deep vein thrombosis in cancer patients
G Malaponte, J Polesel, S Candido, D Sambataro, V Bevelacqua, M Anzaldi, N Vella, V Fiore, L Militello, MC Mazzarino, M Libra, SS Signorelli |
Cytokine | 2013 |
A Consideration of Biomarkers to be Used for Evaluation of Inflammation in Human Nutritional Studies
PC Calder, N Ahluwalia, R Albers, N Bosco, R Bourdet-Sicard, D Haller, ST Holgate, LS Jönsson, ME Latulippe, A Marcos, J Moreines, C M'Rini, M Müller, G Pawelec, RJ Neerven, B Watzl, J Zhao |
British Journal of Nutrition | 2013 |
The Interleukin-6 −147 G/C Polymorphism Is Associated with Increased Risk of Coronary Artery Disease in Young South African Indian Men
A Phulukdaree, S Khan, P Ramkaran, R Govender, D Moodley, AA Chuturgoon |
Metabolic Syndrome and Related Disorders | 2013 |
Association between Interleukin-6 −174G/C polymorphism and the risk of Alzheimer's disease :A meta-analysis
Y Hua, X Guo, Q Huang, Y Kong, X Lu |
International Journal of Neuroscience | 2013 |
Interleukin-6 gene polymorphism (−174 G/C) is associated with toxoplasmic retinochoroiditis
CA Cordeiro, PR Moreira, TF Bessa, GC Costa, WO Dutra, WR Campos, F Oréfice, LH Young, AL Teixeira |
Acta Ophthalmologica | 2013 |
The association of IL-6 and IL-6R gene polymorphisms with chronic periodontitis in a Chinese population
HY Zhang, L Feng, H Wu, XD Xie |
Oral Diseases | 2013 |
Serotonin and interleukin-6: The role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms
M Udina, J Moreno-España, R Navinés, D Giménez, K Langohr, M Gratacòs, L Capuron, R la Torre, R Solà, R Martín-Santos |
Psychoneuroendocrinology | 2013 |
Comparison of cytokine gene polymorphisms among Greek patients with invasive meningococcal disease or viral meningitis
CJ Titmarsh, SM Moscovis, S Hall, G Tzanakaki, K Kesanopoulos, A Xirogianni, RJ Scott, CC Blackwell |
Journal of Medical Microbiology | 2013 |
Circulating interleukin-6 concentration and cognitive decline in old age: the PROSPER study
SP Mooijaart, N Sattar, S Trompet, J Lucke, DJ Stott, I Ford, JW Jukema, RG Westendorp, AJ de Craen |
Journal of Internal Medicine | 2013 |
Lack of association of IL-6 polymorphism with rheumatoid arthritis/type 1 diabetes: A meta-analysis
WD Xu, M Zhou, H Peng, HF Pan, DQ Ye |
Joint Bone Spine | 2013 |
Effect of interleukin-6 and insulin resistance on early virological response of Egyptian chronic hepatitis C patients to combined pegylated interferon plus ribavirin therapy:
TI el Serafi, MM Awad, LA Eldeen, AT el Serafi, M Husin |
Egyptian Liver Journal | 2013 |
Molecular genetic analysis of polymorphisms pertaining to the susceptibility to chronic asthma in Egyptian patients
AA Ali, AA Settin |
The Journal of Basic & Applied Zoology | 2013 |
The association of IL1α and IL1β polymorphisms with susceptibility to systemic lupus erythematosus: A meta-analysis
B Wang, JM Zhu, YG Fan, CC Feng, GM Chen, H Chen, HF Pan, DQ Ye |
Gene | 2013 |
Incidence and risk factors of anti-HLA immunization after pregnancy
E Masson, C Vidal, M Deschamps, S Bongain, C Thevenin, I Dupont, D Rietmulher, F Pouthier, G Mongaillard, J Chabod, C Ferrand, P Tiberghien, JM Rebibou |
Human Immunology | 2013 |
IL1β, IL6 and IL8 gene polymorphisms involvement in recurrent corneal erosion in patients with hereditary stromal corneal dystrophies
AM Kucherenko, VM Pampukha, GI Drozhzhyna, LA Livshits |
Cytology and Genetics | 2013 |
Cytokine Gene Polymorphisms in Kidney Transplantation
T Dhaouadi, I Sfar, R Bardi, S Jendoubi-Ayed, TB Abdallah, K Ayed, Y Gorgi |
Transplantation Proceedings | 2013 |
Polymorphism of inflammatory genes and arsenic methylation capacity are associated with urothelial carcinoma
CC Wu, YK Huang, CJ Chung, CY Huang, YS Pu, HS Shiue, LA Lai, YC Lin, CT Su, YM Hsueh |
Toxicology and Applied Pharmacology | 2013 |
Relation of IL-6, IL-13 and IL-15 gene polymorphisms to the rheumatoid factors, anti-CCP and other measures of rheumatoid arthritis activity
MP Goldbergova, P Nemec, J Lipkova, J Jarkovsky, J Gatterova, D Ambrozkova, A Vasku, M Soucek, N Pavek |
International Journal of Immunogenetics | 2013 |
Association between tumor necrosis factor-α promoter −308 A/G, −238 A/G, interleukin-6 −174 G/C and −572 G/C polymorphisms and periodontal disease: a meta-analysis
GG Song, SJ Choi, JD Ji, YH Lee |
Molecular Biology Reports | 2013 |
Absence d’association du polymorphisme génétique IL-6 avec la polyarthrite rhumatoïde et le diabète type 1 : une méta-analyse
WD Xu, M Zhou, H Peng, HF Pan, DQ Ye |
Revue du Rhumatisme | 2013 |
Genetic component of giant cell arteritis
FD Carmona, MA Gonzalez-Gay, J Martin |
Rheumatology | 2013 |
Interleukin-6 promoter polymorphisms −174 G/C in Brazilian patients with systemic lupus erythematosus
NM Asano, HD Angelo, HA da Silva, MM Maia, OG Lins, PE Souza |
Human Immunology | 2013 |
Interleukin-4, interleukin-4 receptor, and interleukin-18 polymorphisms and rheumatoid arthritis: a meta-analysis
GG Song, SC Bae, JH Kim, YH Lee |
Immunological Investigations | 2013 |
Interleukin 6 gene polymorphism -174 is associated with the diffuse type gastric carcinoma: IL6 -174 and Diffuse Gastric Carcinoma
VM Pohjanen, OP Koivurova, JM Mäkinen, JM Karhukorpi, T Joensuu, PO Koistinen, JM Valtonen, SE Niemelä, RA Karttunen, TJ Karttunen |
Genes, Chromosomes and Cancer | 2013 |
Macrophage subsets and osteoimmunology: tuning of the immunological recognition and effector systems that maintain alveolar bone
C Sima, M Glogauer |
Periodontology 2000 | 2013 |
Influence of interleukin-6 gene -174G>C polymorphism on development of atherosclerosis: A meta-analysis of 50 studies involving 33,514 subjects
YW Yin, JC Li, M Zhang, JZ Wang, BH Li, Y Liu, SQ Liao, MJ Zhang, CY Gao, LL Zhang |
Gene | 2013 |
Interleukin-6 level and gene polymorphism in spontaneous miscarriage: IL6 level and polymorphism in spontaneous miscarriage
M Drozdzik, N Szlarb, M Kurzawski |
Tissue Antigens | 2013 |
Gingival fibroblasts from periodontitis patients exhibit inflammatory characteristics in vitro
KJ Baek, Y Choi, S Ji |
Archives of Oral Biology | 2013 |
Effects of interleukin (IL)-6 gene polymorphisms on recurrent aphthous stomatitis
N Karakus, S Yigit, A Rustemoglu, G Kalkan, N Bozkurt |
Archives of Dermatological Research | 2013 |
Nutrition and Enhanced Sports Performance
ED Hanson, N Eynon |
Nutrition and Enhanced Sports Performance | 2013 |
Significant association of TNFα and IL-6 gene with male infertility—An explorative study in Indian populations of Uttar Pradesh
KK Shukla, S Agnihotri, A Gupta, AA Mahdi, ES Mohamed, SN Sankhwar, P Sharma |
Immunology Letters | 2013 |
Interleukin-6 −174G/C gene polymorphism affects muscle damage response to acute eccentric resistance exercise in elderly obese women
SS Funghetto, J Prestes, AO Silva, DL Farias, TG Teixeira, D Vieira, VC Souza, NM Sousa, JW Navalta, GF Melo, MG Karnikowski |
Experimental Gerontology | 2013 |
Association Between Interleukin-6 Gene Polymorphisms and Bone Mineral Density: A Meta-Analysis
Z Wang, Y Yang, M He, R Wang, J Ma, Y Zhang, L Zhao, K Yu |
Genetic Testing and Molecular Biomarkers | 2013 |
Effect of interleukin-6 polymorphism on risk of preterm birth within population strata: a meta-analysis
W Wu, EA Clark, GJ Stoddard, WS Watkins, MS Esplin, TA Manuck, J Xing, MW Varner, LB Jorde |
BMC genetics | 2013 |
Promoter variants in interleukin-6 and tumor necrosis factor alpha and risk of coronary artery disease in a population from Western India
AA Bhanushali, BR Das |
Indian journal of human genetics | 2013 |
Interleukin 6(-174G/C) Variant and its Circulating Levels in Coronary Artery Disease Patients and Their First Degree Relatives
RK Galimudi, MK Spurthi, C Padala, KG Kumar, S Mudigonda, SG Reddy, MT Aiyengar, SK Sahu, SH Rani |
Inflammation | 2013 |
An interleukin-6 gene promoter polymorphism is associated with polycystic ovary syndrome in South Indian women
VR Tumu, S Govatati, P Guruvaiah, M Deenadayal, S Shivaji, M Bhanoori |
Journal of Assisted Reproduction and Genetics | 2013 |
Genetic variants in transforming growth factor-β gene (TGFB1) affect susceptibility to schizophrenia
D Frydecka, B Misiak, JA Beszlej, L Karabon, E Pawlak-Adamska, A Tomkiewicz, A Partyka, A Jonkisz, A Kiejna |
Molecular Biology Reports | 2013 |
Ethnic variation in interleukin-6 -174 (g/c) polymorphism in the malaysian population
GG Gan, R Subramaniam, LH Lian, V Nadarajan |
Balkan Journal of Medical Genetics | 2013 |
Rather than Rs1800796 polymorphism, expression of interleukin-6 is associated with disease progression of chronic HBV infection in a Chinese Han population
S Tang, Z Liu, Y Zhang, Y He, D Pan, Y Liu, Q Liu, Z Zhang, Y Yuan |
Disease Markers | 2013 |
Sequencing of the IL6 gene in a case-control study of cerebral palsy in children
P Khankhanian, SE Baranzini, BA Johnson, L Madireddy, D Nickles, LA Croen, YW Wu |
BMC Medical Genetics | 2013 |
The -174G/C and -572G/C interleukin 6 promoter gene polymorphisms in mexican patients with rheumatoid arthritis: a case-control study
SA Zavaleta-Muñiz, BT Martín-Márquez, L Gonzalez-Lopez, NG Gonzalez-Montoya, ML Díaz-Toscano, JM Ponce-Guarneros, AJ Ruiz-Padilla, MV Mercado, M Maldonado-González, M Fafutis-Morris, SE Flores-Martínez, EA Martínez-García, JI Gamez-Nava |
Clinical & developmental immunology | 2013 |
Impact of interleukin-6 -174 G>C gene promoter polymorphism on neuroblastoma
F Totaro, F Cimmino, P Pignataro, G Acierno, MD Mariano, L Longo, GP Tonini, A Iolascon, M Capasso |
PloS one | 2013 |
Hypergammaglobulinemia in the pediatric population as a marker for underlying autoimmune disease: a retrospective cohort study
MS Lo, D Zurakowski, MB Son, RP Sundel |
Pediatric Rheumatology | 2013 |
HNRNPA1 interacts with a 5'-flanking distal element of interleukin-6 and upregulates its basal transcription
D Zheng, J Worthington, JF Timms, P Woo |
Genes and Immunity | 2013 |
IL-6 pathway-driven investigation of response to IL-6 receptor inhibition in rheumatoid arthritis
J Wang, A Platt, R Upmanyu, S Germer, G Lei, C Rabe, R Benayed, A Kenwright, A Hemmings, M Martin, O Harari |
BMJ Open | 2013 |
Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration: A Case-Control Study
F Ricci, G Staurenghi, T Lepre, F Missiroli, S Zampatti, R Cascella, P Borgiani, LT Marsella, CM Eandi, A Cusumano, G Novelli, E Giardina |
PloS one | 2013 |
Genetic association of interleukin-6 polymorphism (-174 G/C) with chronic liver diseases and hepatocellular carcinoma
L Giannitrapani, M Soresi, D Balasus, A Licata, G Montalto |
World journal of gastroenterology : WJG | 2013 |
MTHFR Glu429Ala and ERCC5 His46His polymorphisms are associated with prognosis in colorectal cancer patients: analysis of two independent cohorts from Newfoundland
AA Negandhi, A Hyde, E Dicks, W Pollett, BH Younghusband, P Parfrey, RC Green, S Savas |
PloS one | 2013 |
Microbiology and treatment of acute apical abscesses
JF Siqueira, IN Rôças |
Clinical microbiology reviews | 2013 |
Cytokine genetic variations and fatigue among patients with breast cancer
JE Bower, PA Ganz, MR Irwin, S Castellon, J Arevalo, SW Cole |
Journal of Clinical Oncology | 2013 |
Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1
J Denner, M Eschricht, M Lauck, M Semaan, P Schlaermann, H Ryu, L Akyüz |
PloS one | 2013 |
Role of the Promoter Polymorphism IL-6 −174G/C in Dermatomyositis and Systemic Lupus Erythematosus
M Hristova, L Dourmishev, Z Kamenarska, S Nikolova, R Kaneva, A Vinkov, M Baleva, D Monova, V Mitev |
BioMed Research International | 2013 |
Variations in association of Interleukin 6 -G174C single nucleotide polymorphism with type 2 diabetes mellitus—a review
A Nadeem, AK Naveed, MM Hussain, M Aslam, A Siddiqui, SA Saeed |
International Journal of Diabetes in Developing Countries | 2013 |
The Role of Pharmacogenetics in the Treatment of Chronic Hepatitis C Infection
M Kawaguchi-Suzuki, RF Frye |
Nature Communications | 2013 |
Genetics of toll like receptor 9 in ANCA associated vasculitides
CA Husmann, JU Holle, F Moosig, S Mueller, B Wilde, JW Tervaert, L Harper, G Assmann, WL Gross, JT Epplen, S Wieczorek |
Annals of the rheumatic diseases | 2013 |
Polymorphisms in human leukocyte antigens, human platelet antigens, and cytokine genes in hantavirus cardiopulmonary syndrome patients from Ribeirão Preto, Brazil: Human Polymorphisms in Hantavirus Disease
AA Borges, EA Donadi, GM Campos, GG de Figueiredo, FP Saggioro, SJ Badra, NH Deghaide, LT Figueiredo |
Journal of Medical Virology | 2013 |
Low Prevalence of Interleukin-6 Haplotypes Associated with a Decreased Risk of Type 2 Diabetes in Mexican Subjects with a Family History of Type 2 Diabetes
I Zamora-Ginez, AG García-Zapién, SE Flores-Martínez, J Sánchez-Corona, BG Baez-Duarte, E Torres-Rasgado, JR Romero, R Pérez-Fuentes, F Mendoza-Carrera |
Archives of Medical Research | 2013 |
Interleukin-10 promoter (−1082) polymorphism in association with repeated hospital-acquired infections in elderly patients
PN Bories, M Laurent, E Liuu, L Denjean, T Popovici, E Paillaud |
Aging clinical and experimental research | 2013 |
Lack of an Association Between Interleukin-6 −174G/C Polymorphism and Circulating Interleukin-6 Levels in Normal Population: A Meta-Analysis
M Huang, L Wang, H Ma, J Wang, M Xiang |
DNA and Cell Biology | 2013 |
Interleukin-6 polymorphisms and hematologic malignancy: a re-appraisal of evidence from genetic association studies
PD Ziakas, P Karsaliakos, ML Prodromou, E Mylonakis |
Biomarkers | 2013 |
Cytokine single nucleotide polymorphisms in patients’ with gallstone: dose TGF-β gene variants affect gallstone formation?
P Ebadi, S Daneshmandi, A Ghasemi, MH Karimi |
Molecular Biology Reports | 2013 |
Association of IL-6 polymorphisms with hepatocellular carcinoma risk: evidences from a meta-analysis
Y Liu, S Gao, B Du, J Wang |
Tumor Biology | 2013 |
Prognostic value of IL-27 polymorphisms and the susceptibility to epithelial ovarian cancer in a Chinese population
Z Zhang, B Zhou, Y Wu, Q Gao, K Zhang, Y Song, L Zhang, M Xi |
Immunogenetics | 2013 |
Influence of interleukin gene polymorphisms on development of acute pancreatitis: a systematic review and meta-analysis
YW Yin, QQ Sun, JQ Feng, AM Hu, HL Liu, Q Wang |
Molecular Biology Reports | 2013 |
The role of IL6 and ESR1 gene polymorphisms as immunological factors of pregnancy maintenance
AM Kucherenko, II Vorobiova, NV Rudakova, LA Livshits |
Biopolymers and Cell | 2013 |
The genetics of juvenile idiopathic arthritis: current understanding and future prospects
JE Cobb, A Hinks, W Thomson |
Rheumatology | 2013 |
Cytokine Gene Polymorphisms in Childhood Dilated Cardiomyopathy: Interferon- gamma, Tumor Necrosis Factor-alpha and Transforming Growth Factor - beta 1 Genes Are Associated with the Disease in Turkish Patients
SO Balci, N Col-Araz, O Baspinar, T Sever, A Balat, S Pehlivan |
IRAN J PEDIATR | 2013 |
The Emerging Field of Human Social Genomics
GM Slavich, SW Cole |
2013 | |
The Association of the Immune Response Genes to Human Papillomavirus-Related Cervical Disease in a Brazilian Population
AV Marangon, GA Guelsin, JE Visentainer, SD Borelli, MA Watanabe, ME Consolaro, KR Caleffi-Ferracioli, CC Rudnick, AM Sell |
BioMed Research International | 2013 |
Imbalanced Frequencies of Th17 and Treg Cells in Acute Coronary Syndromes Are Mediated by IL-6-STAT3 Signaling
Y Ma, X Yuan, L Deng, W Xu, Y Zheng, C Yue, G Zhang, F Xie, YH Yang, MP Gantier, JP Liu, D Xu, L Shen, MG Frasch |
PloS one | 2013 |
Recipient IL-6-572C/G genotype is associated with reduced incidence of acute rejection following liver transplantation
J Yao, XW Feng, XB Yu, HY Xie, LX Zhu, Z Yang, BJ Wei, SS Zheng, L Zhou |
J INT MED RES | 2013 |
Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration: A Case-Control Study
F Ricci, G Staurenghi, T Lepre, F Missiroli, S Zampatti, R Cascella, P Borgiani, LT Marsella, CM Eandi, A Cusumano, G Novelli, E Giardina, M Federici |
PloS one | 2013 |
Modulation of Cytokine Release and Gene Expression by the Immunosuppressive Domain of gp41 of HIV-1
J Denner, M Eschricht, M Lauck, M Semaan, P Schlaermann, H Ryu, L Akyüz, A Landay |
PloS one | 2013 |
MTHFR Glu429Ala and ERCC5 His46His Polymorphisms Are Associated with Prognosis in Colorectal Cancer Patients: Analysis of Two Independent Cohorts from Newfoundland
AA Negandhi, A Hyde, E Dicks, W Pollett, BH Younghusband, P Parfrey, RC Green, S Savas, XP Miao |
PloS one | 2013 |
Cytokine Genetic Variations and Fatigue Among Patients With Breast Cancer
JE Bower, PA Ganz, MR Irwin, S Castellon, J Arevalo, SW Cole |
Journal of Clinical Oncology | 2013 |
Impact of Interleukin-6 –174 G>C Gene Promoter Polymorphism on Neuroblastoma
F Totaro, F Cimmino, P Pignataro, G Acierno, MD Mariano, L Longo, GP Tonini, A Iolascon, M Capasso, B Mittal |
PloS one | 2013 |
Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels
K Stone, E Woods, SM Szmania, OW Stephens, TK Garg, B Barlogie, JD Shaughnessy, B Hall, M Reddy, A Hoering, E Hansen, F Rhee, M Scheurer |
PloS one | 2013 |
Relevance of IL-6 and MMP-9 to cerebral arteriovenous malformation and hemorrhage
X Li, R Wang, X Wang, X Xue, D Ran, S Wang |
Molecular medicine reports | 2013 |
Association of Cytokines, High Sensitive C-Reactive Protein, VEGF and Beta-Defensin-1 Gene Polymorphisms and Their Protein Expressions with Chronic Periodontitis in the Chinese Population
Y Tian, J Li, L Hao, Y Yue, M Wang, WT Loo, MN Cheung, LW Chow, Q Liu, AY Yip, EL Ng, CY Chow |
The International Journal of Biological Markers | 2013 |
Role of Interleukin 6–174G>C Polymorphism in Primary Open-Angle Glaucoma
C Zimmermann, M Weger, C Faschinger, W Renner, G Mossböck |
European journal of ophthalmology | 2013 |
CCL2/MCP-1 and IL-6 Genetic Polymorphisms for the Prediction of Hematotoxicity Caused by Definitive Chemoradiotherapy
K KURIBAYASHI, S MOTOYAMA, Y SATO, K YOSHINO, T SASAKI, A WAKITA |
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) | 2013 |
Association between tumor necrosis factor-α promoter -308 A/G, -238 A/G, interleukin-6 -174 G/C and -572 G/C polymorphisms and periodontal disease: a meta-analysis.
Song GG, Choi SJ, Ji JD, Lee YH |
Molecular Biology Reports | 2013 |
Influence of interleukin gene polymorphisms on development of acute pancreatitis: a systematic review and meta-analysis.
Yin YW, Sun QQ, Feng JQ, Hu AM, Liu HL, Wang Q |
Molecular Biology Reports | 2013 |
Cytokine single nucleotide polymorphisms in patients' with gallstone: dose TGF-β gene variants affect gallstone formation?
Ebadi P, Daneshmandi S, Ghasemi A, Karimi MH |
Molecular Biology Reports | 2013 |
Association of IL-6 polymorphisms with hepatocellular carcinoma risk: evidences from a meta-analysis.
Liu Y, Gao SJ, Du BX, Wang JJ |
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine | 2013 |
Prognostic value of IL-27 polymorphisms and the susceptibility to epithelial ovarian cancer in a Chinese population.
Zhang Z, Zhou B, Wu Y, Gao Q, Zhang K, Song Y, Zhang L, Xi M |
Immunogenetics | 2013 |
[Personalized medicine in cytokine-targeted therapy].
Behrens F, Köhm M |
2013 | |
Genetic Associations in Acquired Immune-Mediated Bone Marrow Failure Syndromes: Insights in Aplastic Anemia and Chronic Idiopathic Neutropenia
I Mavroudi, HA Papadaki |
Clinical and Developmental Immunology | 2012 |
Cancer Epigenetics
RG Dumitrescu, M Verma |
Cancer Epigenetics | 2012 |
Cancer Epigenetics
RG Dumitrescu, M Verma |
Cancer Epigenetics | 2012 |
Cancer Epigenetics
RG Dumitrescu, M Verma |
Cancer Epigenetics | 2012 |
Efficacy, safety and tolerability of tocilizumab in patients with systemic juvenile idiopathic arthritis
S Yokota, T Tanaka, T Kishimoto |
Therapeutic Advances in Musculoskeletal Diseases | 2012 |
Tocilizumab in the treatment of systemic juvenile idiopathic arthritis
N Nishimoto, Murakami, Tomiita |
Open Access Rheumatology : Research and Reviews | 2012 |
Immunogenetics
FT Christiansen, BD Tait |
Immunogenetics | 2012 |
Immunogenetics
FT Christiansen, BD Tait |
Immunogenetics | 2012 |
Immunogenetics
FT Christiansen, BD Tait |
Immunogenetics | 2012 |
Immunogenetics
FT Christiansen, BD Tait |
Immunogenetics | 2012 |
Immunogenetics
FT Christiansen, BD Tait |
Immunogenetics | 2012 |
A two-SNP IL-6 promoter haplotype is associated with increased lung cancer risk
J Chen, RY Liu, L Yang, J Zhao, X Zhao, D Lu, N Yi, B Han, XF Chen, K Zhang, J He, Z Lei, Y Zhou, B Pasche, X Li, HT Zhang |
Journal of Cancer Research and Clinical Oncology | 2012 |
Developing connections amongst key cytokines and dysregulated germinal centers in autoimmunity
RA Sweet, SK Lee, CG Vinuesa |
Current Opinion in Immunology | 2012 |
Melphalan exposure induces an interleukin-6 deficit in bone marrow stromal cells and osteoblasts
SL Rellick, D Piktel, C Walton, B Hall, W Petros, JE Fortney, M Gencheva, J Denvir, G Hobbs, M Craig, LF Gibson |
Cytokine | 2012 |
A Functional Single-Nucleotide Polymorphism in the Promoter of the Gene Encoding Interleukin 6 Is Associated With Susceptibility to Tuberculosis
G Zhang, B Zhou, W Wang, M Zhang, Y Zhao, Z Wang, L Yang, J Zhai, CG Feng, J Wang, X Chen |
The Journal of Infectious Diseases | 2012 |
Is Still's Disease an Autoinflammatory Syndrome?
L Rossi-Semerano, I Koné-Paut |
International Journal of Inflammation | 2012 |
Association between IL6 -174G/C and cancer: A meta-analysis of 105,482 individuals
RY Liu, X Song, P Chen, Z Lei, J Miao, N Yi, K Zhang, B Pasche, HT Zhang |
Experimental and therapeutic medicine | 2012 |
Polymorphisms of −174G>C and −572G>C in the Interleukin 6 (IL-6) Gene and Coronary Heart Disease Risk: A Meta-Analysis of 27 Research Studies
G Zheng, H Chen, SQ Xiong |
PloS one | 2012 |
Impact of the −174 G > C IL-6 Polymorphism on Bioelectrical Parameters in Obese Subjects after Laparoscopic Adjustable Gastric Banding
LD Renzo, MG Carbonelli, A Bianchi, E Domino, MR Migliore, G Rillo, L Iacopino, ND Daniele, AD Lorenzo |
Journal of Obesity | 2012 |
Human parainfluenza virus serotypes differ in their kinetics of replication and cytokine secretion in human tracheobronchial airway epithelium
A Schaap-Nutt, R Liesman, EJ Bartlett, MA Scull, PL Collins, RJ Pickles, AC Schmidt |
Virology | 2012 |
Histamine: an undercover agent in multiple rare diseases?
A Pino-Ángeles, A Reyes-Palomares, E Melgarejo, F Sánchez-Jiménez |
Journal of Cellular and Molecular Medicine | 2012 |
Genetic Polymorphisms and Bronchiolitis Obliterans Syndrome After Lung Transplantation : Promising Results and Recommendations for the Future
EA Kastelijn, CH van Moorsel, HJ Ruven, JW Lammers, JC Grutters |
Transplantation | 2012 |
−174G/C IL-6 gene promoter polymorphism predicts therapeutic response to TNF-α blockers :
LD Renzo, A Bianchi, R Saraceno, V Calabrese, C Cornelius, L Iacopino, S Chimenti, AD Lorenzo |
Pharmacogenetics and Genomics | 2012 |
Genetic susceptibility to otitis media in childhood
MS Rye, JM Blackwell, SE Jamieson |
The Laryngoscope | 2012 |
Association of interleukin-6 circulating levels with coronary artery disease: A meta-analysis implementing mendelian randomization approach
W Niu, Y Liu, Y Qi, Z Wu, D Zhu, W Jin |
International Journal of Cardiology | 2012 |
Association of NOS2 and potential effect of VEGF, IL6, CCL2 and IL1RN polymorphisms and haplotypes on susceptibility to GCA--a simultaneous study of 130 potentially functional SNPs in 14 candidate genes
A Enjuanes, Y Benavente, J Hernandez-Rodriguez, C Queralt, J Yague, P Jares, S Sanjose, E Campo, MC Cid |
Rheumatology | 2012 |
The association between proinflammatory cytokine polymorphisms and cerebral palsy in very preterm infants
HK Vidak, TC Ivković, M Jokić, R Spaventi, S Kapitanović |
Cytokine | 2012 |
Genetic Susceptibility and the Relationship between Cardiovascular Disease, Immunology, and Psychiatric Illness
S Villafuerte, M Rubenfire, Z Kronfol |
Psychiatry and Heart Disease The Mind Brain and Heart | 2012 |
A Meta-Analysis of the Effects of Interleukin-6 −174 G>C Genetic Polymorphism on Acute Graft-Versus-Host Disease Susceptibility
B Choi, DE Lee, HY Park, S Jeong, SM Lee, E Ji, S Park, JM Oh |
Clinical Therapeutics | 2012 |
Polymorphic variants of the genes encoding intrleukin-6 and fibrinogen: Risk for ischemic stroke and fibrinogen levels
BV Titov, RM Barsova, MY Martynov, AA Nikonova, AV Favorov, EI Gusev, OO Favorova |
Molecular Biology | 2012 |
Role of cytokine gene (IFN-γ, TNF-α, TGF-β1, IL-6, and IL-10) polymorphisms in pathogenesis of acute rheumatic fever in Turkish children
N Col-Araz, S Pehlivan, O Baspinar, S Oguzkan-Balci, T Sever, A Balat |
European Journal of Pediatrics | 2012 |
Tumor necrosis factor-α -308 G>A and interleukin-6 -174 G>C promoter polymorphisms and pemphigus
YM Mosaad, H Fathy, Z Fawzi, MA El-Saied |
Human Immunology | 2012 |
The CC homozygosis of the −174G>C IL-6 polymorphism predicts a lower efficacy of rituximab therapy in rheumatoid arthritis
M Fabris, L Quartuccio, S Lombardi, M Saracco, F Atzeni, A Carletto, M Cimmino, C Fabro, E Pontarini, R Pellerito, LM Bambara, P Sarzi-Puttini, M Cutolo, M Manfredi, M Benucci, P Morassi, F Fischetti, M Padovan, M Govoni, F Curcio, E Tonutti, SD Vita |
Autoimmunity Reviews | 2012 |
Cytokine Gene Polymorphisms in the Susceptibility to Acute Coronary Syndrome
BM Babu, BP Reddy, VH Priya, A Munshi, HS Rani, GS Latha, VD Rao, A Jyothy |
Genetic Testing and Molecular Biomarkers | 2012 |
Polymorphisms of interleukin-1 and interleukin-6 genes on the risk of ischemic stroke in a meta-analysis
F Ye, XQ Jin, GH Chen, XL Den, YQ Zheng, CY Li |
Gene | 2012 |
The association between interleukin-6 polymorphisms and rheumatoid arthritis: a meta-analysis
YH Lee, SC Bae, SJ Choi, JD Ji, GG Song |
Inflammation Research | 2012 |
Genetic and Immunological Evidence Implicates Interleukin 6 as a Susceptibility Gene for Leprosy Type 2 Reaction
AL Sousa, VM Fava, LH Sampaio, CM Martelli, MB Costa, MT Mira, MM Stefani |
The Journal of Infectious Diseases | 2012 |
The -174G/C variant of IL6 as risk factor for mortality and technique failure in a large cohort of peritoneal dialysis patients
M Verduijn, C Marechal, AM Coester, DE Sampimon, EW Boeschoten, FW Dekker, E Goffin, RT Krediet, O Devuyst |
Nephrology Dialysis Transplantation | 2012 |
Interleukin-6 promoter polymorphism and plasma levels in patients with schizophrenia
R Zakharyan, M Petrek, A Arakelyan, F Mrazek, S Atshemyan, A Boyajyan |
Tissue Antigens | 2012 |
Does Clinically Relevant Temperature Change miRNA and Cytokine Expression in Whole Blood?
AT Billeter, M Qadan, D Druen, SA Gardner, T The, HC Polk |
Journal of Interferon & Cytokine Research | 2012 |
Polymorphic variations in IL-1β, IL-6 and IL-10 genes, their circulating serum levels and breast cancer risk in Indian women
S Pooja, P Chaudhary, LV Nayak, S Rajender, KS Saini, D Deol, S Kumar, HK Bid, R Konwar |
Cytokine | 2012 |
Association Between −174 Interleukin-6 Gene Polymorphism and Biological Response to Rituximab in Several Systemic Autoimmune Diseases
G Robledo, CL Dávila-Fajardo, A Márquez, N Ortego-Centeno, JL Rubio, ER Garrido, J Sánchez-Román, FJ García-Hernández, R Ríos-Fernández, MF González-Escribano, MT García, MJ Palma, MM Ayala, J Martín |
DNA and Cell Biology | 2012 |
Is there any relation between IL-6 gene −174 G>C polymorphism and postmenopausal osteoporosis?
D Deveci, ZS Ozkan, H Yuce |
European Journal of Obstetrics & Gynecology and Reproductive Biology | 2012 |
Influence of IL-6 haplotypes on clinical and inflammatory response in aggressive periodontitis
L Nibali, G Pelekos, F D’Aiuto, N Chaudhary, R Habeeb, D Ready, M Parkar, N Donos |
Clinical Oral Investigations | 2012 |
Initial manifestations and clinical course of systemic onset juvenile idiopathic arthritis: A ten-year retrospective study
HY Tsai, JH Lee, HH Yu, LC Wang, YH Yang, BL Chiang |
Journal of the Formosan Medical Association | 2012 |
Association between interleukin-6 gene −174 G/C polymorphism and the risk of coronary heart disease: A meta-analysis of 20 studies including 9619 cases and 10,919 controls
Y Yin, A Hu, Q Sun, H Liu, Q Wang, Y Zeng, R Xu, Z Hou, Z Zhang, S Zhang, M Zhou |
Gene | 2012 |
Do gene polymorphism in IL-1β, TNF-α and IL-6 influence therapeutic response in patients with drug refractory epilepsy?
P Tiwari, R Dwivedi, N Mansoori, R Alam, UK Chauhan, M Tripathi, AK Mukhopadhyay |
Epilepsy Research | 2012 |
No evidence of association between functional polymorphisms located within IL6R and IL6ST genes and systemic sclerosis: IL6R and IL6ST functional polymorphisms in SSc susceptibility
MC Cénit, CP Simeón, V Fonollosa, G Espinosa, E Beltrán, L Sáez-Comet, E Vicente-Rabaneda, FJ García-Hernández, L Martínez-Estupiñán, M Rodríguez-Carballeira, V Hernández, PG Peña, M Fernández-Castro, FJ Narváez, A Pros, M Gallego, R Ríos-Fernández, MT Camps, A Fernández-Nebro, MV Egurbide, P Carreira, MA González-Gay, J Martín |
Tissue Antigens | 2012 |
Association of Single Nucleotide Polymorphisms of Interleukins-1β, -6, and -12B with Contact Lens Keratitis Susceptibility and Severity
NA Carnt, MD Willcox, S Hau, LL Garthwaite, VE Evans, CF Radford, JK Dart, S Chakrabarti, F Stapleton |
Ophthalmology | 2012 |
Associations between interleukin-6 gene −174 C/G and −572 C/G polymorphisms and the risk of gastric cancer: A meta-analysis
YW Yin, QQ Sun, AM Hu, Q Wang, HL Liu, ZZ Hou, YH Zeng, RJ Xu, LB Shi, JB Ma |
Journal of Surgical Oncology | 2012 |
Influence of Cytokine Gene Polymorphisms on Graft Rejection in Turkish Patients with Renal Transplants from Living Related Donors
Y Seyhun, J Mytilineos, A Turkmen, F Oguz, C Kekik, K Ozdilli, I Nane, F Aydin, M Carin |
Transplantation Proceedings | 2012 |
Interleukin-6 promoter variants, prostate cancer risk, and survival
EA Tindall, G Severi, HN Hoang, MC Southey, DR English, JL Hopper, GG Giles, VM Hayes |
The Prostate | 2012 |
Plasma concentrations but not serum concentrations of brain-derived neurotrophic factor are related to pro-inflammatory cytokines in patients undergoing major abdominal surgery
G Chimienti, A Mezzapesa, MT Rotelli, L Lupo, G Pepe |
Clinical Biochemistry | 2012 |
ASSOCIATION OF TUMOR NECROSIS FACTOR α, INTERLEUKIN 6, AND INTERLEUKIN 10 PROMOTER POLYMORPHISM WITH PROLIFERATIVE DIABETIC RETINOPATHY IN TYPE 2 DIABETIC SUBJECTS:
SK Paine, A Sen, S Choudhuri, LK Mondal, IH Chowdhury, A Basu, A Mukherjee, B Bhattacharya |
Retina | 2012 |
Single nucleotide polymorphisms associated with sporadic brain arteriovenous malformations: where do we stand?
CL Sturiale, A Puca, P Sebastiani, I Gatto, A Albanese, CD Rocco, G Maira, R Pola |
Brain | 2012 |
Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability
J Yan, JM Greer, PA McCombe |
Journal of Neuroimmunology | 2012 |
Association of IL-6 polymorphisms with gastric cancer risk: Evidences from a meta-analysis
W Junli, H Wenjun, L Jinxin, N Legen, W Yesheng, Y Fenglian |
Cytokine | 2012 |
IL6 gene polymorphisms and susceptibility to colorectal cancer: a meta-analysis and review
Y Yu, W Wang, S Zhai, S Dang, M Sun |
Molecular Biology Reports | 2012 |
Genes, physical fitness and ageing
N Garatachea, A Lucia |
Ageing Research Reviews | 2012 |
Comparative analysis of IL6 and IL6 receptor gene polymorphisms in mastocytosis
E Rausz, A Szilágyi, B Nedoszytko, M Lange, M Niedoszytko, O Lautner-Csorba, A Falus, I Aladzsity, M Kokai, P Valent, M Marschalko, B Hidvégi, J Szakonyi, J Csomor, J Várkonyi |
British Journal of Haematology | 2012 |
Association of Interleukin-6 Polymorphisms with Obesity and Hyperglycemia in Mexican Adolescents
G Ramírez-López, EP Buen, J Sánchez-Corona, J Salmerón-Castro, F Mendoza-Carrera |
Archives of Medical Research | 2012 |
Interleukin-6 gene −174G>C and −636G>C promoter polymorphisms and prostate cancer risk
JF Magalhães, AJ Cortinhas, CM Albuquerque, CS Baptista, R Ribeiro, C Viegas, A Matos, J Machado, MA Pires, H Guedes-Pinto, A Martins-Bessa, JC Leitão, E Bastos |
Molecular Biology Reports | 2012 |
A study on the association of TNF-α-308, IL-6-174, IL-10-1082 and IL-1RaVNTR gene polymorphisms with rheumatic heart disease in Pakistani patients
S Rehman, N Akhtar, N Saba, S Munir, W Ahmed, A Mohyuddin, A Khanum |
Cytokine | 2012 |
Interleukin-6 Gene Promoter-572 C Allele may Play a Role in Rate of Disease Progression in Multiple Sclerosis
J Yan, J Liu, CY Lin, PA Csurhes, MP Pender, PA McCombe, JM Greer |
International journal of molecular sciences | 2012 |
The lack of association between interleukin-6 gene −174 G/C polymorphism and the risk of type 1 diabetes mellitus: A meta-analysis of 18,152 subjects
YW Yin, QQ Sun, BB Zhang, AM Hu, Q Wang, HL Liu, ZZ Hou, YH Zeng, RJ Xu, LB Shi |
Gene | 2012 |
Association between interleukin-18 polymorphisms and systemic lupus erythematosus: a meta-analysis
GG Song, SJ Choi, JD Ji, YH Lee |
Molecular Biology Reports | 2012 |
-174G/C interleukin-6 gene promoter polymorphism predicts therapeutic response to etanercept in rheumatoid arthritis
I Jančić, N Arsenović-Ranin, M Šefik-Bukilica, S Živojinović, N Damjanov, V Spasovski, S Srzentić, B Stanković, S Pavlović |
Rheumatology International | 2012 |
Expression, polymorphism and methylation pattern of interleukin-6 in periodontal tissues
FA Stefani, MB Viana, AC Dupim, JA Brito, RS Gomez, JE da Costa, PR Moreira |
Immunobiology | 2012 |
AA Amyloidosis: Mount Sinai Experience, 1997-2012
D Bunker, P Gorevic |
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine | 2012 |
Genetic predictors of fatigue in prostate cancer patients treated with androgen deprivation therapy: preliminary findings
HS Jim, JY Park, J Permuth-Wey, MA Rincon, KM Phillips, BJ Small, PB Jacobsen |
Brain, Behavior, and Immunity | 2012 |
Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study
DS O'Mahony, BJ Glavan, TD Holden, C Fong, RA Black, G Rona, P Tejera, DC Christiani, MM Wurfel |
PloS one | 2012 |
Potential of ayurgenomics approach in complex trait research: leads from a pilot study on rheumatoid arthritis
RC Juyal, S Negi, P Wakhode, S Bhat, B Bhat, BK Thelma |
PloS one | 2012 |
Interleukin-6 -634 C/G and -174 G/C polymorphisms in Korean patients undergoing hemodialysis
JH Ryu, SJ Kim |
The Korean Journal of Internal Medicine | 2012 |
When grief makes you sick: bereavement induced systemic inflammation is a question of genotype
CR Schultze-Florey, O Martínez-Maza, L Magpantay, EC Breen, MR Irwin, H Gündel, MF O'Connor |
Brain, Behavior, and Immunity | 2012 |
Evaluation of published single nucleotide polymorphisms associated with acute GVHD
JW Chien, XC Zhang, W Fan, H Wang, LP Zhao, PJ Martin, BE Storer, M Boeckh, EH Warren, JA Hansen |
Blood | 2012 |
Prevention of colitis-associated cancer: natural compounds that target the IL-6 soluble receptor
Cate Moriasi, Dharmalingam Subramaniam, Shanjana Awasthi, Satish Ramalingam, Shrikant Anant |
Anti-cancer agents in medicinal chemistry | 2012 |
Polymorphisms of −174G>C and −572G>C in the Interleukin 6 (IL-6) Gene and Coronary Heart Disease Risk: A Meta-Analysis of 27 Research Studies
G Zheng, H Chen, SQ Xiong, MP Dubé |
PloS one | 2012 |
Is Still's Disease an Autoinflammatory Syndrome?
L Rossi-Semerano, I Koné-Paut |
International Journal of Inflammation | 2012 |
The Association of Polymorphisms in Cytokine Genes with Acute Rejection and the Pathogenesis of Hepatitis B and C in Liver Transplant Recipients
R Yaghobi, MH Karimi, M Namayandeh, B Geramizadeh, S Nikeghbalian, SA Malekhosseini, Y Hosseini |
Laboratory Medicine | 2012 |
The association between interleukin-6 polymorphisms and systemic lupus erythematosus: a meta-analysis
YH Lee, HS Lee, SJ Choi, JD Ji, GG Song |
Lupus | 2012 |
Inflammation and Immune-Related Candidate Gene Associations with Acute Lung Injury Susceptibility and Severity: A Validation Study
DS O'Mahony, BJ Glavan, TD Holden, C Fong, RA Black, G Rona, P Tejera, DC Christiani, MM Wurfel, YG Yao |
PloS one | 2012 |
Genetics of leprosy reactions: an overview
V Fava, M Orlova, A Cobat, A Alcaïs, M Mira, E Schurr |
Memórias do Instituto Oswaldo Cruz | 2012 |
Efficacy, safety and tolerability of tocilizumab in patients with systemic juvenile idiopathic arthritis
S Yokota, T Tanaka, T Kishimoto |
Therapeutic Advances in Musculoskeletal Diseases | 2012 |
Interleukin gene polymorphisms in pneumoconiosis
S Helmig, M Grossmann, J Wübbeling, J Schneider |
International journal of molecular medicine | 2012 |
Influence of the IL6 Gene in Susceptibility to Systemic Sclerosis
MC Cénit, CP Simeón, MC Vonk, JL Callejas-Rubio, G Espinosa, P Carreira, FJ Blanco, JA Narvaez, C Tolosa, JA ROMÁN-IVORRA, I Gómez-García, FJ García-Hernández, M Gallego, R García-Portales, MV Egurbide, VI Fonollosa, PA de la PEÑA, FJ López-Longo, MA González-Gay, R Hesselstrand, G Riemekasten, T Witte, AE Voskuyl, AJ Schuerwegh, R Madhok, C Fonseca, C Denton, A Nordin, ØY Palm, JA van LAAR, N Hunzelmann, JH Distler, A Kreuter, A Herrick, J Worthington, BP Koeleman, TR Radstake, JA Martín |
The Journal of rheumatology | 2012 |
Immunosenescence
JA Bosch, AC Phillips, J M. |
2012 | |
Gene polymorphism and protein of human pro- and anti-inflammatory cytokines in Chinese healthy subjects and chronic periodontitis patients
WT Loo, C Fan, L Bai, Y Yue, Y Dou, M Wang, H Liang, MN Cheung, LW Chow, J Li, Y Tian, L Qing |
Journal of Translational Medicine | 2012 |
The association between interleukin-6 polymorphisms and rheumatoid arthritis: a meta-analysis.
Lee YH, Bae SC, Choi SJ, Ji JD, Song GG |
Inflammation research : official journal of the European Histamine Research Society ... [et al.] | 2012 |
IL6 gene polymorphisms and susceptibility to colorectal cancer: a meta-analysis and review.
Yu Y, Wang W, Zhai S, Dang S, Sun M |
Molecular Biology Reports | 2012 |
Influence of IL-6 haplotypes on clinical and inflammatory response in aggressive periodontitis.
Nibali L, Pelekos G, D'Aiuto F, Chaudhary N, Habeeb R, Ready D, Parkar M, Donos N |
Clinical Oral Investigations | 2012 |
Interleukin-6 gene -174G>C and -636G>C promoter polymorphisms and prostate cancer risk.
Magalhães JF, Cortinhas AJ, Albuquerque CM, Baptista CS, Ribeiro R, Viegas C, Matos A, Machado J, Pires MA, Guedes-Pinto H, Martins-Bessa A, Leitão JC, Bastos E |
Molecular Biology Reports | 2012 |
-174G/C interleukin-6 gene promoter polymorphism predicts therapeutic response to etanercept in rheumatoid arthritis.
Jančić I, Arsenović-Ranin N, Sefik-Bukilica M, Zivojinović S, Damjanov N, Spasovski V, Srzentić S, Stanković B, Pavlović S |
Rheumatology International | 2012 |
Association between interleukin-18 polymorphisms and systemic lupus erythematosus: a meta-analysis.
Song GG, Choi SJ, Ji JD, Lee YH |
Molecular Biology Reports | 2012 |
Role of cytokine gene (IFN-γ, TNF-α, TGF-β1, IL-6, and IL-10) polymorphisms in pathogenesis of acute rheumatic fever in Turkish children.
Col-Araz N, Pehlivan S, Baspinar O, Oguzkan-Balci S, Sever T, Balat A |
European Journal of Pediatrics | 2012 |
PREVENTION OF COLITIS-ASSOCIATED CANCER: NATURAL COMPOUNDS THAT TARGET THE IL-6 SOLUBLE RECEPTOR
Moriasi C, Subramaniam D, Awasthi S, Anant S, Ramalingam S |
Anti-cancer agents in medicinal chemistry | 2012 |
Differential Combination of Cytokine and Interferon- γ +874 T/A Polymorphisms Determines Disease Severity in Pulmonary Tuberculosis
A Ansari, Z Hasan, G Dawood, R Hussain |
PloS one | 2011 |
Biomarkers in Acute Lung Injury: Insights into the Pathogenesis of Acute Lung Injury
LJ Cross, MA Matthay |
Critical Care Clinics | 2011 |
Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review
BH Tan, JA Ross, S Kaasa, F Skorpen, KC Fearon |
Journal of Genetics | 2011 |
Studies of gene variants related to inflammation, oxidative stress, dyslipidemia, and obesity: implications for a nutrigenetic approach
ML Curti, P Jacob, MC Borges, MM Rogero, SR Ferreira |
Journal of Obesity | 2011 |
Association of haplotypes of inflammation-related genes with gastric preneoplastic lesions in African Americans and Caucasians
J Zabaleta, MC Camargo, MD Ritchie, MB Piazuelo, RA Sierra, SD Turner, A Delgado, ET Fontham, BG Schneider, P Correa, AC Ochoa |
International Journal of Cancer | 2011 |
Do Interleukin Polymorphisms Play a Role in the Prevention of Colorectal Adenoma Recurrence by Dietary Flavonols?
G Bobe, G Murphy, PS Albert, LB Sansbury, MR Young, E Lanza, A Schatzkin, NH Colburn, AJ Cross |
European Journal of Cancer Prevention | 2011 |
Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions
ED Mellins, C Macaubas, AA Grom |
Nature Reviews Rheumatology | 2011 |
Advances in Clinical Chemistry
M Mahler |
Advances in Clinical Chemistry Volume 54 | 2011 |
Association of IL1A, IL1B, ILRN, IL6, IL10 and TNF-α polymorphisms with risk and clinical course of multiple sclerosis in a Polish population
D Mirowska-Guzel, G Gromadzka, A Mach, A Czlonkowski, A Czlonkowska |
Journal of Neuroimmunology | 2011 |
Cytokines
L Cassetta, G Poli, M Alfano |
Cytokines | 2011 |
The pathogenesis of oligoarticular/polyarticular vs systemic juvenile idiopathic arthritis
YT Lin, CT Wang, ME Gershwin, BL Chiang |
Autoimmunity Reviews | 2011 |
Promoter region polymorphism (−174 G/C) of interleukin-6 gene and SLE; are they associated?
D Abbas, E Hamdy, MM Helal |
The Egyptian Rheumatologist | 2011 |
Interleukin 6-174G>C polymorphism and risk of aneurysmal subarachnoid hemorrhage: case-control study and meta-analysis
J Pera, T Dziedzic, M Adamski, J Jagiella, M Krupa, M Moskala, A Szczudlik, A Slowik |
Acta Neurologica Scandinavica | 2011 |
Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients
D Lasigliè, E Traggiai, S Federici, M Alessio, A Buoncompagni, A Accogli, S Chiesa, F Penco, A Martini, M Gattorno |
PloS one | 2011 |
Interleukin-6 (-636 c/g) gene polymorphism in korean children with kawasaki disease
HM Ahn, IS Park, SJ Hong, YM Hong |
Korean Circulation Journal | 2011 |
Functional inflammatory genotypes in ischemic stroke: could we use them to predict age of onset and long-term outcome?
S Marousi, A Antonacopoulou, H Kalofonos, P Papathanasopoulos, M Karakantza, J Ellul |
Stroke Research and Treatment | 2011 |
Association of cytokine gene polymorphisms with psoriasis in cases from the nile delta of egypt
AA Settin, HA Hassan, RA El-Baz, TA Hassan |
Indian journal of dermatology | 2011 |
Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study
M Emonts, MJ Hazes, JJ Houwing-Duistermaat, CE van der Jongh, L Vogel, HK Han, JM Wouters, JD Laman, RJ Dolhain |
BMC Medical Genetics | 2011 |
Disturbed Sleep in Pediatric Patients With Leukemia: The Potential Role of <i>Interleukin-6</i> (-174GC) and <i>Tumor Necrosis Factor</i> (-308GA) Polymorphism
K Vallance, J Yang, J Li, VM Crabtree, PS Hinds, BN Mandrell |
Oncology Nursing Forum | 2011 |
De novo 19q13.42 duplications involving NLRP gene cluster in a patient with systemic-onset juvenile idiopathic arthritis
H Tadaki, H Saitsu, A Nishimura-Tadaki, T Imagawa, M Kikuchi, R Hara, U Kaneko, T Kishi, T Miyamae, N Miyake, H Doi, Y Tsurusaki, H Sakai, S Yokota, N Matsumoto |
Journal of Human Genetics | 2011 |
Exonic deletion of CASP10 in a patient presenting with systemic juvenile idiopathic arthritis, but not with autoimmune lymphoproliferative syndrome type IIa
H Tadaki, H Saitsu, H Kanegane, N Miyake, T Imagawa, M Kikuchi, R Hara, U Kaneko, T Kishi, T Miyamae, A Nishimura, H Doi, Y Tsurusaki, H Sakai, S Yokota, N Matsumoto |
International Journal of Immunogenetics | 2011 |
-174G/C interleukin-6 gene polymorphism and the risk of transplanted kidney failure or graft loss during a 5-year follow-up period
M Kocierz, U Siekiera, A Kolonko, H Karkoszka, J Chudek, L Cierpka, A Wiȩcek |
Tissue Antigens | 2011 |
IL-6 promoter polymorphism (−174G/C) and systemic lupus erythematosus
E Hamdy, RA Afify, A Kamal, D Abass, M Mahmoud |
Comparative Clinical Pathology | 2011 |
An overview on the genetic of rheumatoid arthritis: A never-ending story
C Perricone, F Ceccarelli, G Valesini |
Autoimmunity Reviews | 2011 |
MCP-1 −2518 A/G functional polymorphism is associated with increased susceptibility to active pulmonary tuberculosis in Tunisian patients
W Ben-Selma, H Harizi, J Boukadida |
Molecular Biology Reports | 2011 |
Genes and the ageing muscle: a review on genetic association studies
N Garatachea, A Lucía |
AGE | 2011 |
Association of the IL-6 -174G/C gene polymorphism with knee osteoarthritis in a Thai population
S Honsawek, B Deepaisarnsakul, A Tanavalee, P Yuktanandana, P Bumrungpanichthaworn, S Malila, N Saetan |
Genetics and Molecular Research | 2011 |
Interleukin-6 Plasma Levels Are Modulated by a Polymorphism in the NFKB1 Gene and are Associated with Outcome Following Rituximab-Combined Chemotherapy in Diffuse Large B-Cell Non-Hodgkin Lymphoma
M Giachelia, MT Voso, MC Tisi, M Martini, V Bozzoli, G Massini, F D'Alo, LM Larocca, G Leone, S Hohaus |
Leukemia and Lymphoma | 2011 |
Update on the pathogenesis and treatment of systemic idiopathic arthritis :
KA Sikora, AA Grom |
Current Opinion in Pediatrics | 2011 |
Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance
PC Underwood, B Chamarthi, JS Williams, B Sun, A Vaidya, BA Raby, J Lasky-Su, PN Hopkins, GK Adler, GH Williams |
Metabolism | 2011 |
Has dysregulated interleukin-6 gene a role in the development of Alzheimer's disease?
C Capurso |
Neuroscience Letters | 2011 |
A study of the impact of cytokine gene polymorphism in acute rejection of renal transplant recipients
MH Karimi, S Daneshmandi, AA Pourfathollah, B Geramizadeh, R Yaghobi, GA Rais-Jalali, J Roozbeh, S Bolandparvaz |
Molecular Biology Reports | 2011 |
Associations between inflammatory markers, candidate polymorphisms and physical performance in older Danish twins
K Tiainen, M Thinggaard, M Jylhä, E Bladbjerg, K Christensen, L Christiansen |
Experimental Gerontology | 2011 |
Contact lens-related microbial keratitis: how have epidemiology and genetics helped us with pathogenesis and prophylaxis
F Stapleton, N Carnt |
Eye | 2011 |
Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African Americans
FT Ayele, A Doumatey, H Huang, J Zhou, B Charles, M Erdos, J Adeleye, W Balogun, O Fasanmade, T Johnson, J Oli, G Okafor, A Amoah, BA Eghan, K Agyenim-Boateng, J Acheampong, CA Adebamowo, A Herbert, N Gerry, M Christman, G Chen, D Shriner, A Adeyemo, CN Rotimi |
Immunogenetics | 2011 |
Interleukin-6 −174G/C polymorphism and the risk of Alzheimer's disease in Caucasians: A meta-analysis
XM Han, CH Wang, X Sima, SY Liu |
Neuroscience Letters | 2011 |
Effects of the interleukin-6 (IL-6) polymorphism on toxic metal and trace element levels in placental tissues
Z Kayaaltı, D Tekin, V Aliyev, S Yalçın, G Kurtay, T Söylemezoğlu |
Science of The Total Environment | 2011 |
Association of interleukin-6-572G/C gene polymorphisms in the Cantonese population with intracranial aneurysms
G Zhang, Y Tu, W Feng, L Huang, M Li, S Qi |
Journal of the Neurological Sciences | 2011 |
SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS
FD Benedetti, R Schneider |
Textbook of Pediatric Rheumatology | 2011 |
Association of plasma IL-6 and soluble IL-6 receptor levels with the Asp358Ala polymorphism of the IL-6 receptor gene in schizophrenic patients
D Sasayama, C Wakabayashi, H Hori, T Teraishi, K Hattori, M Ota, M Ishikawa, K Arima, T Higuchi, N Amano, H Kunugi |
Journal of Psychiatric Research | 2011 |
The role of interleukin DNA polymorphisms in gastric cancer
A Yuzhalin |
Human Immunology | 2011 |
Association of IL-1β and IL-6 gene polymorphisms with recurrent spontaneous abortion in a Chinese Han population : IL-1β and IL-6 gene polymorphisms in Chinese RSA
X Ma, LJ Xu, J Wang, MM Xian, M Liu |
International Journal of Immunogenetics | 2011 |
Gene–PUFA interactions and obesity risk
C Jourdan, S Kloiber, A Nieters, H Seiler, H Himmerich, MA Kohli, S Lucae, G Wolfram, C Gieger, HE Wichmann, J Linseisen |
British Journal of Nutrition | 2011 |
Association between IL-6 –174G/C polymorphism and acute rejection of renal allograft: Evidence from a meta-analysis
R Lv, X Hu, Y Bai, H Long, L Xu, Z Liu, X Li, H Huang, L Wang, B Ying |
Transplant Immunology | 2011 |
Investigation of TNF-alpha, TGF-beta 1, IL-10, IL-6, IFN-gamma, MBL, GPIA, and IL1A gene polymorphisms in patients with idiopathic thrombocytopenic purpura
M Pehlivan, V Okan, T Sever, SO Balci, M Yilmaz, T Babacan, S Pehlıvan |
Platelets | 2011 |
Interleukin-6 in oral diseases: a review : IL-6 and oral diseases
L Nibali, S Fedele, F D’Aiuto, N Donos |
Oral Diseases | 2011 |
Association between the Interleukin-6 Promoter Polymorphism −174G/C and Serum Lipoprotein(a) Concentrations in Humans
HK Berthold, M Laudes, W Krone, I Gouni-Berthold |
PloS one | 2011 |
Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis
F Ceccarelli, C Perricone, M Fabris, C Alessandri, A Iagnocco, C Fabro, E Pontarini, SD Vita, G Valesini |
Arthritis Research & Therapy | 2011 |
Les applications en rhumatologie: en génomique
P Dieudé, HJ Garchon |
Revue du Rhumatisme | 2011 |
Relationship between the levels of serum high-sensitivity C-reactive protein and interleukin-6 and interleukin-6 gene polymorphisms in type 2 diabetes mellitus
DF Elgayar, SH Aboulsoud |
Comparative Clinical Pathology | 2011 |
IL-6 −174 C/C Genotype Is Not Conclusively a Low IL-6 Production Phenotype
J Nokso-Koivisto, JA Patel, T Chonmaitree |
The Journal of Infectious Diseases | 2011 |
Tumour Necrosis Factor Gene Polymorphism and Disease Prevalence : TNF Gene Polymorphism and Disease Prevalence
T Qidwai, F Khan |
Scandinavian Journal of Immunology | 2011 |
Genetic variations in multiple myeloma I: effect on risk of multiple myeloma : SNP and risk of multiple myeloma patients
A Vangsted, TW Klausen, U Vogel |
European Journal of Haematology | 2011 |
Insulin-like growth factor 1 receptor polymorphism rs2229765 and circulating interleukin-6 level affect male longevity in a population-based prospective study (Treviso Longeva− TRELONG)
D Albani, S Mazzuco, L Polito, S Batelli, G Biella, F Ongaro, DR Gustafson, P Antuono, G Gajo, E Durante, L Caberlotto, A Zanardo, M Siculi, M Gallucci, G Forloni |
The Aging Male | 2011 |
Association of tumor necrosis factor β genetic polymorphism and sepsis susceptibility
F Delongui, CM Grion, MA Watanabe, HK Morimoto, AM Bonametti, JM Oda, AP Kallaur, T Matsuo, EM Reiche |
Experimental and therapeutic medicine | 2011 |
Mendelian Randomization Study of Interleukin-6 in Chronic Obstructive Pulmonary Disease
YM van Durme, L Lahousse, KM Verhamme, L Stolk, M Eijgelsheim, DW Loth, AG Uitterlinden, MM Breteler, GF Joos, A Hofman, BH Stricker, GG Brusselle |
Respiration | 2011 |
Pediatric Coronary Allograft Vasculopathy-A Review of Pathogenesis and Risk Factors : Pediatric CAV Pathogenesis
KR Schumacher, RJ Gajarski, S Urschel |
Congenital Heart Disease | 2011 |
Genetic predisposition to respiratory infection and sepsis
LP Chung, GW Waterer |
Critical Reviews in Clinical Laboratory Sciences | 2011 |
Cytokine gene polymorphism and asthma susceptibility, progress and control level
S Daneshmandi, AA Pourfathollah, Z Pourpak, H Heidarnazhad, PA Kalvanagh |
Molecular Biology Reports | 2011 |
The association of genetic polymorphisms with cerebral palsy: a meta-analysis : Association of Genetic Polymorphisms with CP
D Wu, YF Zou, XY Xu, XL Feng, L Yang, GC Zhang, XS Bu, JL Tang |
Developmental Medicine & Child Neurology | 2011 |
Blastocystis infection is associated with irritable bowel syndrome in a Mexican patient population
DE Jimenez-Gonzalez, WA Martinez-Flores, J Reyes-Gordillo, ME Ramirez-Miranda, S Arroyo-Escalante, M Romero-Valdovinos, D Stark, V Souza-Saldivar, F Martinez-Hernandez, A Flisser, A Olivo-Diaz, P Maravilla |
Parasitology Research | 2011 |
Body composition changes after laparoscopic adjustable gastric banding: what is the role of −174G>C interleukin-6 promoter gene polymorphism in the therapeutic strategy?
LD Renzo, MG Carbonelli, A Bianchi, L Iacopino, R Fiorito, ND Daniele, AD Lorenzo |
International Journal of Obesity | 2011 |
Harper's Textbook of Pediatric Dermatology: Irvine/Harper's Textbook of Pediatric Dermatology
R Happle |
Harper's Textbook of Pediatric Dermatology: Irvine/Harper's Textbook of Pediatric Dermatology | 2011 |
Impact of interleukin-6 promoter polymorphism and serum interleukin-6 level on the acute inflammation and neovascularization stages of patients with Eales’ disease
A Sen, SK Paine, IH Chowdhury, A Mukherjee, S Choudhuri, A Saha, LK Mandal, B Bhattacharya |
Molecular vision | 2011 |
Polymorphisms in interleukin-6-6331 influences the susceptibility of a Chinese population to gastric cancer
J Yu, Y Jia, KF Cheung, Z Zeng, L Tian, S Wang, P Hu, JJ Sung |
Cancer Investigation | 2011 |
Distributions of interleukin-6 (IL-6) promoter and metallothionein 2A (MT2A) core promoter region gene polymorphisms and their associations with aging in Turkish population
Z Kayaaltı, L Şahiner, ME Durakoğlugil, T Söylemezoğlu |
Archives of Gerontology and Geriatrics | 2011 |
A polymorphism linked to elevated levels of interferon-γ is associated with an increased risk of cytomegalovirus disease among Caucasian lung transplant recipients at a single center
D Mitsani, MH Nguyen, DM Girnita, K Spichty, EJ Kwak, FP Silveira, Y Toyoda, JM Pilewski, M Crespo, JK Bhama, R Abdel-Massih, D Zaldonis, A Zeevi, CJ Clancy |
The Journal of Heart and Lung Transplantation | 2011 |
Gender differences in the IL6 -174G>C and ESR2 1730G>A polymorphisms and the risk of Parkinson's disease
MS Luciano, L Ozelius, RB Lipton, D Raymond, SB Bressman, R Saunders-Pullman |
Neuroscience Letters | 2011 |
Antagonistic pleiotropy at the human IL6 promoter confers genetic resilience to the pro-inflammatory effects of adverse social conditions in adolescence
SW Cole, JM Arevalo, K Manu, EH Telzer, L Kiang, JE Bower, MR Irwin, AJ Fuligni |
Developmental Psychology | 2011 |
Repeated course antenatal steroids, inflammation gene polymorphisms, and neurodevelopmental outcomes at age 2
EA Clark, L Mele, RJ Wapner, CY Spong, Y Sorokin, A Peaceman, JD Iams, KJ Leveno, M Harper, SN Caritis, BM Mercer, JM Thorp, SM Ramin, M Carpenter, DJ Rouse, |
American Journal of Obstetrics and Gynecology | 2011 |
Cytokine gene polymorphisms and length of gestation
M Harper, SL Zheng, E Thom, MA Klebanoff, J Thorp, Y Sorokin, MW Varner, JD Iams, M Dinsmoor, BM Mercer, DJ Rouse, SM Ramin, GD Anderson, |
Obstetrics and gynecology | 2011 |
Comparative insights into the regulation of inflammation: Levels and predictors of interleukin 6 and interleukin 10 in young adults in the Philippines
TW McDade, PS Tallman, LS Adair, B Judith, CW Kuzawa |
American Journal of Physical Anthropology | 2011 |
Inflammation and Genetics: An Insight in the Centenarian Model
T Iannitti, B Palmieri |
Human Biology | 2011 |
The Interleukin-6 Gene Promoter Polymorphism -174 and Atherosclerotic Events in Overweight Transplanted Patients
J Bamoulid, C Courivaud, M Deschamps, B Gaugler, P Tiberghien, JM Chalopin, P Saas, D Ducloux |
Journal of Transplantation | 2011 |
The Interleukin-6 Promoter −597/−572/−174 Genotype Does Not Affect Interleukin-6 Production in Hemodialysis Patients
F Schulte, P Schnülle, P Bugert, H Klüter, M Müller-Steinhardt |
Journal of Interferon & Cytokine Research | 2011 |
Association Study of BMP4, IL6, Leptin, MMP3, and MTNR1B Gene Promoter Polymorphisms and Adolescent Idiopathic Scoliosis:
M Mórocz, Á Czibula, ZB Grózer, A Szécsényi, PZ Álmos, I Raskó, T Illés |
Spine | 2011 |
IL-6 polymorphism associated with fatal outcome in patients with severe traumatic brain injury
AL Libera, A Regner, J Paoli, L Centenaro, TT Martins, D Simon |
Brain Injury | 2011 |
Genetic and Environmental Influences on the Plasma Interleukin-6 Concentration in Patients with a Recent Myocardial Infarction: A Case–Control Study
M Bennermo, M Nordin, P Lundman, S Boqvist, C Held, A Samnegård, CG Ericsson, A Silveira, A Hamsten, MM Nastase, P Tornvall |
Journal of Interferon & Cytokine Research | 2011 |
Interleukin-6 −174 G/C Promoter Polymorphism is Associated with Persistence of Chlamydia pneumoniae Antibodies in Young Men: IL-6 -174G/C SNP and C. pneumoniae
A Rantala, T Lajunen, R Juvonen, M Paldanius, S Silvennoinen-Kassinen, A Peitso, O Vainio, M Leinonen, P Saikku |
Scandinavian Journal of Immunology | 2011 |
IL-1 cluster gene polymorphisms in Turkish patients with Behçet’s disease: IL-1 cluster gene polymorphisms in BD
AA Özçimen, K Dilek, Ü Bingöl, H Sarıcaoğlu, A Sarandöl, Ö Taşkapılıoğlu, M Yurtkuran, MA Yurtkuran, HB Oral |
International Journal of Immunogenetics | 2011 |
The G to A polymorphism at -597 of the interleukin-6 gene is extremely rare in southern Han Chinese
SP Gao, M Pan, C Chen, LJ Ge, MH Jiang, H Luan, JG Zheng, XT Deng, HY Pan, JH Zhu |
Cytokine | 2011 |
Association of IL-6 and IL-6R gene polymorphisms with susceptibility to respiratory tract infections in young Finnish men
A Rantala, T Lajunen, R Juvonen, S Silvennoinen-Kassinen, A Peitso, O Vainio, P Saikku, M Leinonen |
Human Immunology | 2011 |
Lack of an association between interleukin-6 gene promoter polymorphisms (−174G/C, −572G/C) and ischemic heart disease and/or ischemic stroke: A meta-analysis
Y Ma, RK Tang, X Yang, GG Peng, Y Liu, XM Wang, BH Wu, JM Yu |
Human Immunology | 2011 |
Detection and characterization of interleukin-6 gene variants in Canis familiaris: Association studies with periodontal disease
F Morinha, C Albuquerque, J Requicha, I Dias, J Leitão, I Gut, H Guedes-Pinto, C Viegas, E Bastos |
Gene | 2011 |
Cytokine gene polymorphism in microscopic colitis association with the IL-6-174 GG genotype:
RM Koskela, TJ Karttunen, SE Niemelä, JK Lehtola, RS Bloigu, RA Karttunen |
European Journal of Gastroenterology & Hepatology | 2011 |
Interleukin-4 Gene Polymorphisms Confer Behçet’s Disease in Turkish Population: IL-4 Gene Polymorphisms Confer BD
HB Oral, K Dilek, AA Özçimen, Ö Taşkapılıoğlu, Ü Bingöl, A Sarandöl, H Sarıcaoğlu, M Yurtkuran, MA Yurtkuran |
Scandinavian Journal of Immunology | 2011 |
The role of IL-6, IL-8 and MCP-1 and their promoter polymorphisms IL-6 -174GC, IL-8 -251AT and MCP-1 -2518AG in the risk of venous thromboembolism: A case-control study
MF Matos, DM Lourenço, CM Orikaza, JA Bajerl, MA Noguti, VM Morelli |
Thrombosis Research | 2011 |
Modelling epistasis in genetic disease using Petri nets, evolutionary computation and frequent itemset mining
M Mayo, L Beretta |
Expert Systems with Applications | 2011 |
Role of Inflammation-Related Gene Polymorphisms in Patients with Central Retinal Vein Occlusion
R Maier, I Steinbrugger, A Haas, M Selimovic, W Renner, Y El-Shabrawi, C Werner, A Wedrich, O Schmut, M Weger |
Ophthalmology | 2011 |
The Presence of Functionally Relevant Toll-Like Receptor Polymorphisms Does Not Significantly Correlate with Development or Outcome of Sepsis
P Ahmad-Nejad, C Denz, W Zimmer, J Wacker, P Bugert, C Weiss, M Quintel, M Neumaier |
Genetic Testing and Molecular Biomarkers | 2011 |
Role of interleukin-6 −174 G/C promoter polymorphism in trace metal levels of autopsy kidney and liver tissues
S Yalçın, Z Kayaaltı, T Söylemezoğlu |
International Journal of Hygiene and Environmental Health | 2011 |
Possible effect of gene polymorphisms on the release of TNFα and IL1 cytokines in coal workers’ pneumoconiosis
I Ates, B Yucesoy, A Yucel, SH Suzen, Y Karakas, A Karakaya |
Experimental and Toxicologic Pathology | 2011 |
Tumor necrosis factor-α and interleukin-6 expression in leukocytes and their association with polymorphisms and bone markers in diabetic individuals treated with pioglitazone
ST Himelfarb, FA Silva, SS Arazi, CM Farjado, A Garofalo, MC Bertolami, A Bertolami, A Faludi, MF Sampaio, AA Rezende, RD Hirata, MH Hirata |
Drug Metabolism and Drug Interactions | 2011 |
Genetic Variations in the Interleukin-6 and Interleukin-8 Genes and the Interleukin-6 Receptor Gene in Delirium
BC van Munster, AH Zwinderman, SE de Rooij |
Rejuvenation Research | 2011 |
Lack of association between IL-1 and IL-6 gene polymorphisms and myocardial infarction in Turkish population: Lack of association between IL-1 and IL-6 gene polymorphisms
A Coker, A Arman, O Soylu, T Tezel, A Yildirim |
International Journal of Immunogenetics | 2011 |
Factors related to disability: Evidence from the “Treviso Longeva (TRELONG) Study”
M Gallucci, F Ongaro, S Meggiolaro, P Antuono, DR Gustafson, GL Forloni, D Albani, GB Gajo, E Durante, L Caberlotto, A Zanardo, M Siculi, G Muffato, C Regini |
Archives of Gerontology and Geriatrics | 2011 |
Interleukin-1β and Interleukin-6 Expression and Gene Polymorphisms in Subjects with Peri-Implant Disease: Interleukin-1β and Interleukin-6 Expression and Gene Polymorphisms in Subjects with Peri-Implant Disease
RF Melo, BM Lopes, JA Shibli, E Marcantonio, RA Marcantonio, GM Galli |
Clinical Implant Dentistry and Related Research | 2011 |
Looking at paediatric rheumatology over the past 50 years
P Woo, RE Petty |
Rheumatology | 2011 |
Association of cytokine gene alleles with the inflammation of human periodontal tissue
AV Safonova, AN Petrin, SD Arutyunov, VN Tsarev, LA Akulenko, AO Zorina, DV Rebrikov, AV Rubanovich, SA Borinskaya, NK Yankovsky |
Acta Naturae | 2011 |
Association of Interleukin-6 Gene Polymorphism With Angina Pectoris
FG Amorim, BP Campagnaro, CL Tonini, AP Norbim, ID Louro, EC Vasquez, JA Arruda, SS Meyrelles |
Angiology | 2011 |
Role of IL-1 Beta in the Development of Human TH17 Cells: Lesson from NLPR3 Mutated Patients
D Lasigliè, E Traggiai, S Federici, M Alessio, A Buoncompagni, A Accogli, S Chiesa, F Penco, A Martini, M Gattorno, JE Khoury |
PloS one | 2011 |
Functional Inflammatory Genotypes in Ischemic Stroke: Could We Use Them to Predict Age of Onset and Long-Term Outcome?
S Marousi, A Antonacopoulou, H Kalofonos, P Papathanasopoulos, M Karakantza, J Ellul |
Stroke Research and Treatment | 2011 |
Association between variable number tandem repeats within the 3′ flanking region of the interleukin-6 gene and systemic lupus erythematosus in Korean patients
JY Jeon, HA Kim, SH Kim, CH Suh |
Lupus | 2011 |
Differential Combination of Cytokine and Interferon- γ +874 T/A Polymorphisms Determines Disease Severity in Pulmonary Tuberculosis
A Ansari, Z Hasan, G Dawood, R Hussain, MM Heimesaat |
PloS one | 2011 |
Exercício físico como fator de prevenção aos processos inflamatórios decorrentes do envelhecimento
CJ Brito, AC Volp, OT Nóbrega, FL Júnior, EL Mendes, AF Roas, JF Barros, C Córdova |
MOTRIZ | 2011 |
Effects of 174 G/C polymorphism in the promoter region of the interleukin-6 gene on plasma IL-6 levels and muscle strength in elderly women
DS Pereira, DM Garcia, FM Narciso, ML Santos, JM Dias, BZ Queiroz, ER Souza, OT Nóbrega, LS Pereira |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 2011 |
IL-10 gene promoter polymorphisms and leprosy in a Colombian population sample
N Cardona-Castro, M Sánchez-Jiménez, W Rojas, G Bedoya-Berrío |
Biomédica | 2011 |
HIV and Liver Disease
KE Sherman |
2011 | |
Cytokine gene polymorphism and asthma susceptibility, progress and control level.
Daneshmandi S, Pourfathollah AA, Pourpak Z, Heidarnazhad H, Kalvanagh PA |
Molecular Biology Reports | 2011 |
Tumour necrosis factor gene polymorphism and disease prevalence.
Qidwai T, Khan F |
Scandinavian Journal of Immunology | 2011 |
Blastocystis infection is associated with irritable bowel syndrome in a Mexican patient population.
Jimenez-Gonzalez DE, Martinez-Flores WA, Reyes-Gordillo J, Ramirez-Miranda ME, Arroyo-Escalante S, Romero-Valdovinos M, Stark D, Souza-Saldivar V, Martinez-Hernandez F, Flisser A, Olivo-Diaz A, Maravilla P |
Parasitology Research | 2011 |
Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation
K Kawane, H Tanaka, Y Kitahara, S Shimaoka, S Nagata |
Proceedings of the National Academy of Sciences | 2010 |
Failure of interferon gamma to induce the anti-inflammatory interleukin 18 binding protein in familial hemophagocytosis
CA Nold-Petry, T Lehrnbecher, A Jarisch, D Schwabe, JM Pfeilschifter, H Muhl, MF Nold |
PloS one | 2010 |
Interleukin-6-174 G/C Polymorphism is Not Associated with IL-6 Expression and Susceptibility to Sporadic Colon Cancer
T Čačev, M Jokić, B Lončar, Š Križanac, S Kapitanović |
DNA and Cell Biology | 2010 |
Association between interleukin-6 polymorphisms and periodontitis in Indian non-smokers
F Franch-Chillida, L Nibali, I Madden, N Donos, P Brett |
Journal of Clinical Periodontology | 2010 |
The interleukin 6 -174 C/C genotype predicts greater rhinovirus illness
WJ Doyle, ML Casselbrant, HS Li-Korotky, AP Doyle, CY Lo, R Turner, S Cohen |
The Journal of Infectious Diseases | 2010 |
Gene polymorphisms in chronic periodontitis
ML Laine, BG Loos, W Crielaard |
International journal of dentistry | 2010 |
Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer
M Sugimoto, Y Yamaoka, T Furuta |
World journal of gastroenterology : WJG | 2010 |
Computational identification of gene-social environment interaction at the human IL6 locus
SW Cole, JM Arevalo, R Takahashi, EK Sloan, SK Lutgendorf, AK Sood, JF Sheridan, TE Seeman |
Proceedings of the National Academy of Sciences | 2010 |
Commonly studied polymorphisms in inflammatory cytokine genes show only minor effects on mortality and related risk factors in nonagenarians
S Dato, KS Krabbe, M Thinggaard, BK Pedersen, K Christensen, H Bruunsgaard, L Christiansen |
The journals of gerontology. Series A, Biological sciences and medical sciences | 2010 |
Interaction between fibrinogen and IL-6 genetic variants and associations with cardiovascular disease risk in the Cardiovascular Health Study
CL Carty, P Heagerty, SR Heckbert, GP Jarvik, LA Lange, M Cushman, RP Tracy, AP Reiner |
Annals of Human Genetics | 2010 |
Activation of JAK-STAT and nitric oxide signaling as a mechanism for donor heart dysfunction
CF Bulcao, KM D'Souza, R Malhotra, M Staron, JY Duffy, PK Pandalai, V Jeevanandam, SA Akhter |
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | 2010 |
Tocilizumab: The evidence for its place in the treatment of juvenile idiopathic arthritis
T Herlin |
Core evidence | 2010 |
Interleukin-6 promoter polymorphism (-174 G/C) in Indian patients with chronic periodontitis
NB Kalburgi, A Bhatia, S Bilichodmath, SR Patil, SB Mangalekar, K Bhat |
Journal of Oral Science | 2010 |
Viral hepatitis: Human genes that limit infection
F Grünhage, J Nattermann |
Best Practice & Research Clinical Gastroenterology | 2010 |
Gene-gene interaction in regulatory T–cell function in atopy and asthma development in childhood
RW Bottema, M Kerkhof, NE Reijmerink, C Thijs, HA Smit, CP van Schayck, B Brunekreef, AJ van Oosterhout, DS Postma, GH Koppelman |
Journal of Allergy and Clinical Immunology | 2010 |
Influence of CRP, IL6, and TNFA Gene Polymorphisms on Circulating Levels of C-Reactive Protein in Mexican Adolescents
F Mendoza-Carrera, G Ramírez-López, NA Ayala-Martínez, AG García-Zapién, SE Flores-Martínez, J Sánchez-Corona |
Archives of Medical Research | 2010 |
Genetic Risk Factors for Post-Infectious Irritable Bowel Syndrome Following a Waterborne Outbreak of Gastroenteritis
AC Villani, M Lemire, M Thabane, A Belisle, G Geneau, AX Garg, WF Clark, P Moayyedi, SM Collins, D Franchimont, JK Marshall |
Gastroenterology | 2010 |
A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis
AM Valdes, NK Arden, A Tamm, K Kisand, S Doherty, E Pola, C Cooper, A Tamm, KR Muir, I Kerna, D Hart, F O'Neil, W Zhang, TD Spector, RA Maciewicz, M Doherty |
Osteoarthritis and Cartilage | 2010 |
A 3-factor epistatic model predicts digital ulcers in Italian scleroderma patients
L Beretta, A Santaniello, M Mayo, F Cappiello, M Marchini, R Scorza |
European Journal of Internal Medicine | 2010 |
Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism
MM Beckers, HJ Ruven, FJ Haas, PA Doevendans, H Cate, MH Prins, DH Biesma |
European Journal of Internal Medicine | 2010 |
The −174 G/C polymorphism of the IL6 gene is associated with elite power performance
JR Ruiz, A Buxens, M Artieda, D Arteta, C Santiago, G Rodríguez-Romo, JI Lao, F Gómez-Gallego, A Lucia |
Journal of Science and Medicine in Sport | 2010 |
Genetic polymorphisms of interleukin-6 modulate fibrosis progression in mild chronic hepatitis C
E Falleti, C Fabris, C Vandelli, C Colletta, A Cussigh, C Smirne, E Fontanini, S Cmet, R Minisini, D Bitetto, P Toniutto, M Pirisi |
Human Immunology | 2010 |
EPOC: inflamación bronquial y sistémica
CC Macario, JP de Tajes, EC Lanus |
Archivos de Bronconeumología | 2010 |
TNF-α −308G>A and IL-6 −174G>C polymorphisms in Tunisian patients with coronary artery disease
L Ghazouani, SB Khalifa, N Abboud, KB Hamda, AB Khalfallah, N Brahim, WY Almawi, T Mahjoub |
Clinical Biochemistry | 2010 |
Preliminary Evidence of an Association Between a Functional IL6 Polymorphism and Fatigue and Sleep Disturbance in Oncology Patients and Their Family Caregivers
C Miaskowski, M Dodd, K Lee, C West, SM Paul, BA Cooper, W Wara, PS Swift, LB Dunn, BE Aouizerat |
Journal of Pain and Symptom Management | 2010 |
Combined Effect of Inflammatory Gene Polymorphisms and the Risk of Ischemic Stroke in a Prospective Cohort of Subjects With Type 2 Diabetes: A Go-DARTS Study
CN Palmer, CH Kimber, AS Doney, AS Proia, AD Morris, E Gaetani, M Quarta, RC Smith, R Pola |
Diabetes | 2010 |
The interleukin-6 gene −572C/G promoter polymorphism modifies Alzheimer's risk in APOE ɛ4 carriers
M Wang, J Jia |
Neuroscience Letters | 2010 |
Pharmaceutical Sciences Encyclopedia: Drug Discovery, Development, and Manufacturing
CD Davis, UM Hanumegowda |
Pharmaceutical Sciences Encyclopedia: Drug Discovery, Development, and Manufacturing | 2010 |
Interleukin 6–174 G/C promoter and variable number of tandem repeats (VNTR) gene polymorphisms in sporadic Alzheimer's disease
C Capurso, V Solfrizzi, AM Colacicco, A D'Introno, V Frisardi, BP Imbimbo, M Lorusso, G Vendemiale, M Denitto, A Santamato, D Seripa, A Pilotto, P Fiore, A Capurso, F Panza |
Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2010 |
The association of IL-1β, IL-2, and IL-6 gene polymorphisms with bone mineral density and osteoporosis in postmenopausal women
B Czerny, A Kaminski, M Kurzawski, D Kotrych, K Safranow, V Dziedziejko, A Bohatyrewicz, A Pawlik |
European Journal of Obstetrics & Gynecology and Reproductive Biology | 2010 |
Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced interleukin-6 secretion
MS Shey, AK Randhawa, M Bowmaker, E Smith, TJ Scriba, M Kock, H Mahomed, G Hussey, TR Hawn, WA Hanekom |
Genes and Immunity | 2010 |
Association between lymphotoxin-α (tumor necrosis factor-β) intron polymorphism and predisposition to severe sepsis is modified by gender and age:
E Watanabe, TG Buchman, H Hirasawa, BA Zehnbauer |
Critical Care Medicine | 2010 |
Interleukin-6 gene polymorphism in Iranian patients with systemic lupus erythematosus
EM Godarzi, EK Sarvestani, E Aflaki, Z Amirghofran |
Clinical Rheumatology | 2010 |
Inflammatory genetic markers of prostate cancer risk
EA Tindall, VM Hayes, DC Petersen |
Cancers | 2010 |
Graves’ disease and gene polymorphism of TNF-α, IL-2, IL-6, IL-12, and IFN-γ
M Anvari, O Khalilzadeh, A Esteghamati, F Momen-Heravi, M Mahmoudi, SA Esfahani, A Rashidi, A Amirzargar |
Endocrine | 2010 |
Asociación entre el polimorfismo genético de la interleucina-1β (3953 T/C) y la hernia discal lumbar sintomática
JP Aparicio, EL Fernández, HM Prieto, JP Vázquez, IF Bances, VF Henriksen, PL Fernández, JC Menéndez, EV Garay, VA Álvarez |
Revista Española de Cirugía Ortopédica y Traumatología | 2010 |
Linkage and association of proinflammatory cytokines genes IL-6, IFNG and TNF with multiple sclerosis
OY Makarycheva, EY Tsareva, MA Sudomoina, OG Kulakova, OV Bykova, NV Gol’tsova, LM Kuzenkova, AN Boiko, OO Favorova |
Molecular Biology | 2010 |
Is the −174 C/G polymorphism of the IL6 gene associated with elite power performance? A replication study with two different Caucasian cohorts: −174 C/G Polymorphism and sports performance
N Eynon, JR Ruiz, Y Meckel, C Santiago, C Fiuza-Luces, F Gómez-Gallego, J Oliveira, A Lucia |
Experimental Physiology | 2010 |
Influence of IL1B polymorphism on CpG island hypermethylation in Helicobacter pylori-infected gastric cancer
EJ Yoo, SY Park, NY Cho, N Kim, HS Lee, D Kim, GH Kang |
Virchows Archiv | 2010 |
Association of cytokine genetic polymorphisms with the humoral immune response to recombinant vaccine against HBV in infants
LC Macedo, AP Isolani, JE Visentainer, RA Moliterno |
Journal of Medical Virology | 2010 |
Maternal interleukin-6 (−174) C/C polymorphism is associated with chorioamnionitis and cystic periventricular leucomalacia of the preterm infant
B Resch, A Radinger, C Mannhalter, B Horvath, A Binder, W Zenz, W Walcher, J Haas, WD Müller, B Pertl |
Journal of Perinatology | 2010 |
Lack of association between IL-6 −174G/C gene polymorphism and Chagas disease
OA Torres, JE Calzada, Y Beraún, CA Morillo, A González, CI González, J Martín |
Tissue Antigens | 2010 |
A Mediterranean diet rich in virgin olive oil may reverse the effects of the -174G/C IL6 gene variant on 3-year body weight change
C Razquin, JA Martinez, MA Martinez-Gonzalez, J Fernández-Crehuet, JM Santos, A Marti |
Molecular Nutrition & Food Research | 2010 |
Association of genetic polymorphisms and risk of late post-transplantation infection in pediatric heart recipients
EL Ohmann, MM Brooks, SA Webber, DM Girnita, RE Ferrell, GJ Burckart, R Chinnock, C Canter, L Addonizio, D Bernstein, JK Kirklin, DC Naftel, A Zeevi |
The Journal of Heart and Lung Transplantation | 2010 |
Analysis of cytokine genes polymorphism as markers for inhibitor development in haemophilia A
D Chaves, A Belisário, G Castro, M Santoro, C Rodrigues |
International Journal of Immunogenetics | 2010 |
Tumor necrosis factor α, interleukin-6 and interleukin-10 polymorphisms in preeclampsia
P Vural, S Degirmencioglu, NY Saral, A Demirkan, C Akgul, G Yildirim, H Issever, H Eroglu |
Journal of Obstetrics and Gynaecology Research | 2010 |
The association of functional polymorphisms of IL-6 gene promoter with ischemic stroke: Analysis in two Chinese populations
Y Tong, Z Wang, Y Geng, J Liu, R Zhang, Q Lin, X Li, D Huang, S Gao, D Hu, Y Li, J Cheng, Z Lu |
Biochemical and Biophysical Research Communications | 2010 |
The IL-6 −174G/C polymorphism and renal scarring in children with first acute pyelonephritis
B Spasojević-Dimitrijeva, M Živković, A Stanković, L Stojković, M Kostić |
Pediatric Nephrology | 2010 |
Interleukin-6 gene –174 C/G and apolipoprotein E gene polymorphisms and the risk of Alzheimer disease in a Polish population
A Klimkowicz-Mrowiec, P Wotkow, K Spisak, A Maruszak, M Styczyńska, M Barcikowska, A Szczudlik, A Słowik |
Neurologia i Neurochirurgia Polska | 2010 |
IL-6 SNP diversity among four ethnic groups as revealed by bead-based liquid array profiling: IL-6 SNP diversity among four ethnic groups
M Ivanova, J Ruiqing, S Kawai, M Matsushita, N Ochiai, E Maruya, H Saji |
International Journal of Immunogenetics | 2010 |
Interleukin-6 and interleukin-10 gene polymorphism, endothelial dysfunction, and postoperative prognosis in patients with peripheral arterial disease
AL Stoica, E Stoica, I Constantinescu, V Uscatescu, C Ginghina |
Journal of Vascular Surgery | 2010 |
Sex-specific effects of CNTF, IL6 and UCP2 polymorphisms on weight gain
AG Heidema, P Wang, CT van Rossum, EJ Feskens, JM Boer, FG Bouwman, P Veer, EC Mariman |
Physiology & Behavior | 2010 |
Association between the genetic polymorphism of interleukin-1ß (3953 T/C) and symptomatic lumbar herniated disc
JP Aparicio, EL Fernández, HM Prieto, JP Vázquez, IF Bances, VF Henriksen, PL Fernández, JC Menéndez, EV Garay, VA Álvarez |
Revista Española de Cirugía Ortopédica y Traumatología (English Edition) | 2010 |
Lack of Association Between the Promoter Polymorphisms of MMP-3 and IL-6 Genes and Adolescent Idiopathic Scoliosis: A Case-Control Study in a Chinese Han Population
Z Liu, NL Tang, XB Cao, WJ Liu, XS Qiu, JC Cheng, Y Qiu |
Spine | 2010 |
Association Between Interleukin-6 −174 Polymorphism and Aggregatibacter actinomycetemcomitans in Chronic Periodontitis
L Nibali, N Donos, S Farrell, D Ready, J Pratten, YK Tu, F D'Aiuto |
Journal of Periodontology | 2010 |
The genetics of sporadic ruptured and unruptured intracranial aneurysms: a genetic meta-analysis of 8 genes and 13 polymorphisms in approximately 20,000 individuals: Clinical article
P McColgan, KZ Thant, P Sharma |
Journal of Neurosurgery | 2010 |
Graft Inflammation and Histologic Indicators of Kidney Chronic Allograft Failure: Low-Expressing Interleukin-10 Genotypes Cannot Be Ignored:
F Khan, A Sar, I Gonul, H Benediktsson, J Doulla, S Yilmaz, N Berka |
Transplantation | 2010 |
Endogenous bacterial flora in pregnant women and the influence of maternal genetic variation: Genital tract microflora in pregnancy and gene polymorphisms
MR Genc, A Onderdonk |
BJOG: An International Journal of Obstetrics & Gynaecology | 2010 |
Association of IL-6 promoter and IFN-γ gene polymorphisms with acute rejection of liver transplantation
MH Karimi, S Daneshmandi, AA Pourfathollah, B Geramizadeh, SA Malekhosseini, S Nikeghbalian, R Yaghobi, S Bolandparvaz |
Molecular Biology Reports | 2010 |
Patient-tailored therapy in rheumatoid arthritis: an editorial review:
HU Scherer, T Dörner, GR Burmester |
Current Opinion in Rheumatology | 2010 |
Cytokine Genetic Polymorphisms and Susceptibility to Kawasaki Disease in Taiwanese Children
KP Weng, TY Ho, YH Chiao, JT Cheng, KS Hsieh, SH Huang, SF Ou, KH Liu, CJ Hsu, PJ Lu, M Hsiao, LP Ger |
Circulation journal : official journal of the Japanese Circulation Society | 2010 |
IL-6 −174G>C polymorphism and cancer risk: a meta-analysis involving 29,377 cases and 37,739 controls
B Xu, XB Niu, ZD Wang, W Cheng, N Tong, YY Mi, ZC Min, J Tao, PC Li, W Zhang, HF Wu, ZD Zhang, ZJ Wang, LX Hua, NH Feng, XR Wang |
Molecular Biology Reports | 2010 |
Interleukin-6 promoter polymorphism −174 G/C is associated with nephritis in Portuguese Caucasian systemic lupus erythematosus patients
MJ Santos, D Fernandes, S Capela, JC Silva, JE Fonseca |
Clinical Rheumatology | 2010 |
The polymorphisms G(−174)C in IL6 gene and G(−1082)A in IL10 gene are associated with poor outcomes in patients with acute coronary syndrome
KA Blagodatskikh, MA Evdokimova, YV Agapkina, AG Nikitin, AN Brovkin, AA Pushkov, EG Blagodatskikh, OY Kudryashova, VS Osmolovskaya, LO Minushkina, MS Kochkina, ND Selezneva, EN Dankovtseva, OS Chumakova, TN Baklanova, PA Talyzin, NE Reznichenko, OP Donetskaya, SN Tereshchenko, ES Krasil’nikova, NA Dzhaiani, EV Akatova, MG Glezer, AS Galyavich, VB Zakirova, NA Koziolova, IV Timofeeva, AV Yagoda, OI Boeva, LI Katel’nitskaya, EV Khorolets, SV Shlyk, EG Volkova, MP Margaryan, IO Guz’, VO Konstantinov, NV Timofeeva, BA Sidorenko, DA Zateishchikov, VV Nosikov |
Molecular Biology | 2010 |
Interleukin 6 promoter polymorphisms influence the outcome of chronic hepatitis C
A Cussigh, E Falleti, C Fabris, D Bitetto, S Cmet, E Fontanini, S Bignulin, E Fornasiere, E Fumolo, R Minisini, M Pirisi, P Toniutto |
Immunogenetics | 2010 |
HLA-DRB1*1501 intensifies the impact of IL-6 promoter polymorphism on the susceptibility to multiple sclerosis in an Iranian population
M Shahbazi, H Ebadi, D Fathi, D Roshandel, M Mohamadhosseni, A Tahmasebi, S Shahbazi, M Zamani, A Rashidbaghan |
Multiple sclerosis (Houndmills, Basingstoke, England) | 2010 |
Gene Polymorphisms in Chronic Periodontitis
ML Laine, BG Loos, W Crielaard |
International journal of dentistry | 2010 |
Association of Interleukin-6 Haplotypes, Obesity, and Metabolic Abnormalities in a Population of Central Mexico
I Zamora-Ginez, MC Sánchez-Guillén, R Pérez-Fuentes, BG Baez-Duarte, E Brambila, A García-Zapién, F Mendoza-Carrera |
Laboratory Medicine | 2010 |
The Role of Genetic Variation in Muscle Strength
M Kostek, MJ Hubal, LS Pescatello |
American journal of lifestyle medicine | 2010 |
Are elite endurance athletes genetically predisposed to lower disease risk?
F Gómez-Gallego, JR Ruiz, A Buxens, S Altmäe, M Artieda, C Santiago, M González-Freire, Z Verde, D Arteta, A Martínez, D Tejedor, JI Lao, J Arenas, A Lucia |
Physiological genomics | 2010 |
Interleukin 6 Gene Polymorphisms Are Associated with Systemic Lupus Erythematosus in Koreans
JY Jeon, HA Kim, SH Kim, HS Park, CH Suh |
The Journal of rheumatology | 2010 |
Polymorphism in interleukin-6 gene is associated with bone mineral density in patients with adolescent idiopathic scoliosis
JS Lee, KT Suh, IS Eun |
The Journal of Bone & Joint Surgery | 2010 |
Molecular Basis for Therapy of AIDS-Defining Cancers
DP Dittmer, SE Krown |
2010 | |
Intelligent Information and Database Systems
NT Nguyen, MT Le, J Świątek |
2010 | |
Chemo Fog
RB Raffa, RJ Tallarida |
2010 | |
Interleukin-1 beta and interleukin-6 gene polymorphism associations with angiographically assessed coronary artery disease in Brazilians
DL Rios, CC Cerqueira, R Bonfim-Silva, LJ Araújo, JF Pereira, SR Gadelha, AA Barbosa |
Cytokine | 2010 |
Biological pathways and genetic variables involved in pain.
Shi Q, Cleeland CS, Klepstad P, Miaskowski C, Pedersen NL |
Quality of Life Research | 2010 |
Polymorphisms of IL-6 174 G/C, IL-10 -592 C/A and risk of HIV/AIDS among North Indian population.
Sobti RC, Berhane N, Mahedi SA, Kler R, Hosseini SA, Kuttiat V, Wanchu A |
Molecular and Cellular Biochemistry | 2010 |
The IL-6 -174G/C polymorphism and renal scarring in children with first acute pyelonephritis.
Spasojević-Dimitrijeva B, Zivković M, Stanković A, Stojković L, Kostić M |
Pediatric nephrology (Berlin, Germany) | 2010 |
Graves' disease and gene polymorphism of TNF-α, IL-2, IL-6, IL-12, and IFN-γ.
Anvari M, Khalilzadeh O, Esteghamati A, Momen-Heravi F, Mahmoudi M, Esfahani SA, Rashidi A, Amirzargar A |
Endocrine | 2010 |
Interleukin 6 promoter polymorphisms influence the outcome of chronic hepatitis C.
Cussigh A, Falleti E, Fabris C, Bitetto D, Cmet S, Fontanini E, Bignulin S, Fornasiere E, Fumolo E, Minisini R, Pirisi M, Toniutto P |
Immunogenetics | 2010 |
IL-6 -174G>C polymorphism and cancer risk: a meta-analysis involving 29,377 cases and 37,739 controls.
Xu B, Niu XB, Wang ZD, Cheng W, Tong N, Mi YY, Min ZC, Tao J, Li PC, Zhang W, Wu HF, Zhang ZD, Wang ZJ, Hua LX, Feng NH, Wang XR |
Molecular Biology Reports | 2010 |
A variant near the interleukin-6 gene is associated with fat mass in Caucasian men.
Andersson N, Strandberg L, Nilsson S, Adamovic S, Karlsson MK, Ljunggren O, Mellström D, Lane NE, Zmuda JM, Nielsen C, Orwoll E, Lorentzon M, Ohlsson C, Jansson JO |
International Journal of Obesity | 2010 |
Interleukin-6 promoter polymorphism -174 G/C is associated with nephritis in Portuguese Caucasian systemic lupus erythematosus patients.
Santos MJ, Fernandes D, Capela S, da Silva JC, Fonseca JE |
Clinical Rheumatology | 2010 |
Influence of IL1B polymorphism on CpG island hypermethylation in Helicobacter pylori-infected gastric cancer.
Yoo EJ, Park SY, Cho NY, Kim N, Lee HS, Kim D, Kang GH |
Virchows Archiv : an international journal of pathology | 2010 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)
SL Masters, A Simon, I Aksentijevich, DL Kastner |
Annual Review of Immunology | 2009 |
Role for Interleukin-6 in COPD-Related Pulmonary Hypertension
A Chaouat, L Savale, C Chouaid, L Tu, B Sztrymf, M Canuet, B Maitre, B Housset, C Brandt, PL Corvoisier, E Weitzenblum, S Eddahibi, S Adnot |
Chest | 2009 |
Serum interleukin-6 levels in colorectal cancer patients—a summary of published results
H Knüpfer, R Preiss |
International Journal of Colorectal Disease | 2009 |
Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer
KK Tsilidis, KJ Helzlsouer, MW Smith, V Grinberg, J Hoffman-Bolton, SL Clipp, K Visvanathan, EA Platz |
Cancer Causes & Control | 2009 |
Genetic ancestry modifies pharmacogenetic gene–gene interaction for asthma
Corvol H, De Giacomo A, Eng C, Seibold M, Ziv E, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Thyne S, Watson HG, Meade K, LeNoir M, Avila PC, Choudhry S, Burchard EG |
Pharmacogenetics and Genomics | 2009 |
Frontiers in Neuroscience
K Panickar, S Bhathena |
Fat Detection | 2009 |
Interleukin-6 promoter polymorphism and cardiovascular risk factors: The Health 2000 Survey
A Riikola, K Sipilä, M Kähönen, A Jula, MS Nieminen, L Moilanen, YA Kesäniemi, T Lehtimäki, J Hulkkonen |
Atherosclerosis | 2009 |
Phospholipase A2 and cyclooxygenase 2 genes influence the risk of interferon-alpha-induced depression by regulating polyunsaturated fatty acids levels
KP Su, SY Huang, CY Peng, HC Lai, CL Huang, YC Chen, KJ Aitchison, CM Pariante |
Biological Psychiatry | 2009 |
Optimized PCR with sequence specific primers (PCR-SSP) for fast and efficient determination of Interleukin-6 Promoter -597/-572/-174Haplotypes
M Müller-Steinhardt, F Schulte, H Klüter, P Bugert |
BMC Research Notes | 2009 |
PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3)
L Dossus, R Kaaks, F Canzian, D Albanes, SI Berndt, H Boeing, J Buring, SJ Chanock, F Clavel-Chapelon, HS Feigelson, JM Gaziano, E Giovannucci, C Gonzalez, CA Haiman, G Hallmans, SE Hankinson, RB Hayes, BE Henderson, RN Hoover, DJ Hunter, KT Khaw, LN Kolonel, P Kraft, J Ma, LL Marchand, E Lund, PH Peeters, M Stampfer, DO Stram, G Thomas, MJ Thun, A Tjonneland, D Trichopoulos, R Tumino, E Riboli, J Virtamo, SJ Weinstein, M Yeager, RG Ziegler, DG Cox |
Carcinogenesis | 2009 |
Interleukin-6 polymorphisms modify the risk of periodontitis: a systematic review and meta-analysis
M Shao, P Huang, R Cheng, T Hu |
Journal of Zhejiang University. Science. B | 2009 |
Variation in cytokine genes can contribute to severity of acetabular osteolysis and risk for revision in patients with ABG 1 total hip arthroplasty: a genetic association study
J Gallo, F Mrazek, M Petrek |
BMC Medical Genetics | 2009 |
Systemic JIA: new developments in the understanding of the pathophysiology and therapy
SJ Vastert, W Kuis, AA Grom |
Best practice & research. Clinical rheumatology | 2009 |
A polymorphism in NFKB1 is associated with improved effect of interferon-{alpha} maintenance treatment of patients with multiple myeloma after high-dose treatment with stem cell support
AJ Vangsted, TW Klausen, P Gimsing, NF Andersen, N Abildgaard, H Gregersen, U Vogel |
Haematologica | 2009 |
Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease
O Combarros, CM van Duijn, N Hammond, O Belbin, A Arias-Vásquez, M Cortina-Borja, MG Lehmann, YS Aulchenko, M Schuur, H Kölsch, R Heun, GK Wilcock, K Brown, PG Kehoe, R Harrison, E Coto, V Alvarez, P Deloukas, I Mateo, R Gwilliam, K Morgan, DR Warden, AD Smith, DJ Lehmann |
Journal of Neuroinflammation | 2009 |
What epidemiology has told us about risk factors and aetiopathogenesis in rheumatic diseases
JE Oliver, AJ Silman |
Arthritis Research & Therapy | 2009 |
Bench-to-bedside review: Association of genetic variation with sepsis
AM Sutherland, KR Walley |
Critical Care | 2009 |
Interleukin-6 plasma level increases with age in an Italian elderly population ("The Treviso Longeva"-Trelong-study) with a sex-specific contribution of rs1800795 polymorphism
D Albani, S Batelli, L Polito, F Prato, M Pesaresi, GB Gajo, SD Angeli, A Zanardo, D Galimberti, E Scarpini, M Gallucci, G Forloni |
Age (Dordrecht, Netherlands) | 2009 |
Associations of IL6 polymorphisms with lung function decline and COPD
JQ He, MG Foreman, K Shumansky, X Zhang, L Akhabir, DD Sin, SF Man, DL DeMeo, AA Litonjua, EK Silverman, JE Connett, NR Anthonisen, RA Wise, PD Paré, AJ Sandford |
Thorax | 2009 |
C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older
BL Pierce, ML Biggs, M DeCambre, AP Reiner, C Li, A Fitzpatrick, CS Carlson, JL Stanford, MA Austin |
Cancer causes & control : CCC | 2009 |
Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion
I Steinbrugger, A Haas, R Maier, W Renner, M Mayer, C Werner, A Wedrich, Y El-Shabrawi, O Schmut, M Weger |
Molecular vision | 2009 |
The −174 G/C Polymorphism in Interleukin-6 (IL-6) Promoter Region is Associated with Serum IL-6 and Carcinoembryonic Antigen Levels in Patients with Colorectal Cancers in Taiwan
KY Yeh, YY Li, LL Hsieh, JR Chen, RP Tang |
Journal of Clinical Immunology | 2009 |
The −174GG Interleukin-6 Genotype Is Protective From Retinopathy and Nephropathy in Juvenile Onset Type 1 Diabetes Mellitus
J Myśliwska, K Zorena, M Myśliwiec, E Malinowska, K Raczyńska, A Balcerska |
Pediatric Research | 2009 |
DNA variants, plasma levels and variability of Interleukin-6 in myocardial infarction survivors: Results from the AIRGENE study
P Ljungman, T Bellander, F Nyberg, E Lampa, B Jacquemin, M Kolz, T Lanki, J Mitropoulos, M Müller, S Picciotto, R Pistelli, R Rückerl, W Koenig, A Peters |
Thrombosis Research | 2009 |
Association between genetic polymorphisms in cytokine genes and recurrent miscarriage – a meta-analysis
I Medica, S Ostojic, N Pereza, A Kastrin, B Peterlin |
Reproductive BioMedicine Online | 2009 |
Polymorphism in the IL6 promoter region is associated with the risk factors and markers of subclinical atherosclerosis in men: The Cardiovascular Risk in Young Finns Study
J Hulkkonen, T Lehtimäki, N Mononen, M Juonala, N Hutri-Kähönen, L Taittonen, J Marniemi, T Nieminen, J Viikari, O Raitakari, M Kähönen |
Atherosclerosis | 2009 |
Gene polymorphism at the interleukin 6 -174 G>C locus affects the outcome of chronic hepatitis B
C Fabris, P Toniutto, D Bitetto, G Fattovich, E Falleti, E Fontanini, A Cussigh, R Minisini, G Occhino, M Pirisi |
Journal of Infection | 2009 |
Comparative analysis of IL6 promoter and receptor polymorphisms in myelodysplasia and multiple myeloma
I Aladzsity, M Kovács, Á Semsei, A Falus, Á Szilágyi, I Karádi, G Varga, G Füst, J Várkonyi |
Leukemia Research | 2009 |
Is Still's disease an autoinflammatory syndrome?
F Hayem |
Joint Bone Spine | 2009 |
Gene polymorphisms and pharmacogenetics in rheumatoid arthritis
I Rego-Pérez, M Fernández-Moreno, V Carreira-García, FJ Blanco |
Reumatolog ía Cl ínica (English Edition) | 2009 |
Interleukin-6 -174 and -572 Genotypes and the Volume of Deep Gray Matter in Preterm Infants
M Reiman, R Parkkola, H Lapinleimu, L Lehtonen, L Haataja |
Pediatric Research | 2009 |
Kelley's Textbook of Rheumatology
J Degroot, AM Zuurmond, PP Tak |
Kelley's Textbook of Rheumatology | 2009 |
Translational strategies to implement personalized medicine: rheumatoid arthritis examples
BH Littman |
Personalized Medicine | 2009 |
The impact of "high-producer" interleukin-6 haplotypes on cardiovascular morbidity and mortality in a kidney transplant population
B Krüger, A Walberer, S Farkas, F Tokmak, A Obed, P Schenker, B Henning, HJ Schlitt, BK Krämer, B Banas |
Transplantation Proceedings | 2009 |
Lack of an association between a functional polymorphism in the interleukin-6 gene promoter and breast cancer risk: a meta-analysis involving 25,703 subjects
KD Yu, GH Di, L Fan, AX Chen, C Yang, ZM Shao |
Breast Cancer Research and Treatment | 2009 |
Oligoarticular and polyarticular JIA: epidemiology and pathogenesis
C Macaubas, K Nguyen, D Milojevic, JL Park, ED Mellins |
Nature Reviews Rheumatology | 2009 |
Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index
C Huth, T Illig, C Herder, C Gieger, H Grallert, C Vollmert, W Rathmann, YH Hamid, O Pedersen, T Hansen, B Thorand, C Meisinger, A Doring, N Klopp, H Gohlke, W Lieb, C Hengstenberg, V Lyssenko, L Groop, H Ireland, JW Stephens, IW Asterholm, JO Jansson, H Boeing, M Mohlig, HM Stringham, M Boehnke, J Tuomilehto, JM Fernandez-Real, A Lopez-Bermejo, L Gallart, J Vendrell, SE Humphries, F Kronenberg, HE Wichmann, IM Heid |
Annals of Medicine | 2009 |
Polimorfismos genéticos y farmacogenética en la artritis reumatoide
I Rego-Pérez, M Fernández-Moreno, V Carreira-García, FJ Blanco |
Reumatología Clínica | 2009 |
Host Genetic Variants in the Interleukin-6 Promoter Predict Poor Outcome in Patients with Estrogen Receptor-Positive, Node-Positive Breast Cancer
A DeMichele, R Gray, M Horn, J Chen, R Aplenc, WP Vaughan, MS Tallman |
Cancer research | 2009 |
The interleukin-6, serotonin transporter, and monoamine oxidase A genes and endurance performance during the South African Ironman Triathlon
L Milander, DJ Stein, M Collins |
Applied Physiology, Nutrition, and Metabolism | 2009 |
Interleukin-6 genotype and risk for cerebral palsy in term and near-term infants
YW Wu, LA Croen, AR Torres, JV de Water, JK Grether, NN Hsu |
Annals of Neurology | 2009 |
The Additive Contribution from Inflammatory Genetic Markers on the Severity of Cardiovascular Disease
KK Berg, HO Madsen, P Garred, R Wiseth, S Gunnes, V Videm |
Scandinavian Journal of Immunology | 2009 |
Implications of cytokine gene polymorphisms on the orchestration of the immune response: Lessons learned from oral diseases
WO Dutra, PR Moreira, PE Souza, KJ Gollob, RS Gomez |
Cytokine & Growth Factor Reviews | 2009 |
Higher IL-6 levels but not IL6 −174G>C or −572G>C genotype are associated with post-operative complication following coronary artery bypass graft (CABG) surgery
J Sanders, E Hawe, DJ Brull, C Hubbart, GD Lowe, A Rumley, SE Humphries, HE Montgomery |
Atherosclerosis | 2009 |
The influence of class II transactivator and interleukin-6 polymorphisms on the production of antibodies to donor human leucocyte antigen mismatches in renal allograft recipients
J Martin, J Worthington, S Harris, S Martin |
International Journal of Immunogenetics | 2009 |
IL6 genotype and creatine kinase response to exercise
J Lappalainen |
European Journal of Applied Physiology | 2009 |
IL-6 −174 genotype associated with the extent of periodontal disease in type 1 diabetic subjects
T Raunio, M Knuuttila, L Hiltunen, R Karttunen, O Vainio, T Tervonen |
Journal of Clinical Periodontology | 2009 |
Genetic polymorphisms in non-alcoholic fatty liver disease: Interleukin-6−174G/C polymorphism is associated with non-alcoholic steatohepatitis
L Carulli, I Canedi, S Rondinella, S Lombardini, D Ganazzi, S Fargion, MD Palma, A Lonardo, M Ricchi, M Bertolotti, N Carulli, P Loria |
Digestive and Liver Disease | 2009 |
Influence of interleukin-6 G-174C gene polymorphism on coronary artery disease, cardiovascular complications and mortality in dialysis patients
S Aker, C Bantis, P Reis, N Kuhr, C Schwandt, B Grabensee, P Heering, K Ivens |
Nephrology Dialysis Transplantation | 2009 |
The Effects of Genetic Polymorphisms of IL-6, IL-8, and IL-10 on Helicobacter pylori-induced Gastroduodenal Diseases in Korea:
JM Kang, N Kim, DH Lee, JH Park, MK Lee, JS Kim, HC Jung, IS Song |
Journal of Clinical Gastroenterology | 2009 |
Differential cytokine profiles in juvenile idiopathic arthritis subtypes revealed by cluster analysis
HJ Ham, W Jager, JW Bijlsma, BJ Prakken, RJ de Boer |
Rheumatology | 2009 |
Cytokine and cytokine receptor gene polymorphisms and their functionality
AJ Smith, SE Humphries |
Cytokine & Growth Factor Reviews | 2009 |
Periodontal infectogenomics
L Nibali, N Donos, B Henderson |
Journal of Medical Microbiology | 2009 |
Gene–gene interaction between CARD8 and interleukin-6 reduces Alzheimer’s disease risk
A Fontalba, O Gutiérrez, J Llorca, I Mateo, JL Vázquez-Higuera, J Berciano, JL Fernández-Luna, O Combarros |
Journal of Neurology | 2009 |
Fatty Acids, IL6, and TNFα Polymorphisms: An Example of Nutrigenetics in Crohn's Disease
CS Guerreiro, P Ferreira, L Tavares, PM Santos, M Neves, M Brito, M Cravo |
The American Journal of Gastroenterology | 2009 |
The IL6 -174G/C polymorphism is associated with celiac disease susceptibility in girls
B Dema, A Martínez, M Fernández-Arquero, C Maluenda, I Polanco, MÁ Figueredo, EG de la Concha, E Urcelay, C Núñez |
Human Immunology | 2009 |
Effect of interleukin-6 polymorphisms on human longevity: A systematic review and meta-analysis
DD Bona, S Vasto, C Capurso, L Christiansen, L Deiana, C Franceschi, M Hurme, E Mocchegiani, M Rea, D Lio, G Candore, C Caruso |
Ageing Research Reviews | 2009 |
Genetic susceptibility to viral exposure may increase the risk of cerebral palsy
M DJUKIC, CS GIBSON, AH MacLENNAN, PN GOLDWATER, EA HAAN, G McMICHAEL, K PRIEST, GA DEKKER, WM HAGUE, A CHAN, Z RUDZKI, PV ESSEN, TY KHONG, MR MORTON, E RANIERI, H SCOTT, H TAPP, G CASEY |
Australian and New Zealand Journal of Obstetrics and Gynaecology | 2009 |
Association of interleukin-6 (IL-6)-174G/C gene polymorphism with cardiovascular disease in patients with rheumatoid arthritis: The role of obesity and smoking
VF Panoulas, A Stavropoulos-Kalinoglou, GS Metsios, JP Smith, HJ Milionis, KM Douglas, P Nightingale, GD Kitas |
Atherosclerosis | 2009 |
Effects of CD14, TLR2, TLR4, LPB, and IL-6 Gene Polymorphisms on Chlamydia pneumoniae Growth in Human Macrophages In Vitro
K Poikonen, T Lajunen, S Silvennoinen-Kassinen, M Leinonen, P Saikku |
Scandinavian Journal of Immunology | 2009 |
Polymorphisms of IL-6 174 G/C, IL-10 -592 C/A and risk of HIV/AIDS among North Indian population
RC Sobti, N Berhane, SA Mahedi, R Kler, SA Hosseini, V Kuttiat, A Wanchu |
Molecular and Cellular Biochemistry | 2009 |
The (-174) G/C polymorphism in the interleukin-6 gene is associated with risk of papillary thyroid carcinoma in Turkish patients
AG Özgen, M Karadeniz, M Erdogan, A Berdeli, F Saygili, C Yilmaz |
Journal of Endocrinological Investigation | 2009 |
Association between IL6 gene variants −174G>C and −572G>C and serum IL-6 levels: Interactions with social position in the Whitehall II cohort
SC Sanderson, M Kumari, EJ Brunner, MA Miller, A Rumley, GD Lowe, MG Marmot, SE Humphries |
Atherosclerosis | 2009 |
Interaction between smoking and the interleukin-6 gene affects systemic levels of inflammatory biomarkers
J Sunyer, F Forastiere, J Pekkanen, E Plana, M Kolz, R Pistelli, B Jacquemin, I Bruske-Hohlfeld, C Pitsavos, T Bellander, W Koenig, A Peters |
Nicotine & Tobacco Research | 2009 |
Tocilizumab and missed personalized medicine opportunities for patients with rheumatoid arthritis?
BH Littman |
Arthritis & Rheumatism | 2009 |
Association of HLA-DRB1, interleukin-6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population-A candidate gene approach
FA Castro, K Haimila, I Sareneva, M Schmitt, J Lorenzo, N Kunkel, R Kumar, A Försti, L Kjellberg, G Hallmans, M Lehtinen, K Hemminki, M Pawlita |
International Journal of Cancer | 2009 |
Polymorphisms at GLUT1 gene are not associated with the development of TSP/HAM in Brazilian HTLV-1 infected individuals and the discovery of a new polymorphism at GLUT1 gene
GC Costa, R Azevedo, SR Gadelha, SH Kashima, G Muricy, VN Olavarria, DT Covas, OM Takayanagui, B Galvão-Castro, LC Alcantara |
Journal of Medical Virology | 2009 |
Day-to-day variation in plasma interleukin-6 concentrations in older adults
M Picotte, CG Campbell, WG Thorland |
Cytokine | 2009 |
Association of IL6 and CCL2 gene polymorphisms with the outcome of allogeneic haematopoietic stem cell transplantation
Z Ambruzova, F Mrazek, L Raida, P Jindra, B Vidan-Jeras, E Faber, J Pretnar, K Indrak, M Petrek |
Bone Marrow Transplantation | 2009 |
La maladie de Still : une maladie auto-inflammatoire ?
F Hayem |
Revue du Rhumatisme | 2009 |
Molecular screening of interleukin-6 gene promoter and influence of −174G/C polymorphism on breast cancer
M Chérel, L Campion, S Bézieau, M Campone, J Charrier, J Gaschet, G Ricolleau, W Gouraud, C Charbonnel, P Jézéquel |
Cytokine | 2009 |
Proinflammatory Cytokine Gene Polymorphisms in Irritable Bowel Syndrome
E Barkhordari, N Rezaei, B Ansaripour, P Larki, M Alighardashi, HR Ahmadi-Ashtiani, M Mahmoudi, MR Keramati, P Habibollahi, M Bashashati, N Ebrahimi-Daryani, AA Amirzargar |
Journal of Clinical Immunology | 2009 |
A common variation in the promoter region of interleukin-6 gene shows association with exercise performance
A Huuskonen, M Tanskanen, J Lappalainen, N Oksala, H Kyröläinen, M Atalay |
Journal of sports science & medicine | 2009 |
Association between metabolic disturbances and G-174C polymorphism of interleukin-6 gene in obese children
B Pyrzak, A Wisniewska, A Majcher, K Popko, M Wasik, U Demkow |
European Journal of Medical Research | 2009 |
Pathogenic mechanisms of postinfectious functional gastrointestinal disorders: Results 3 years after gastroenteritis
F Mearin, A Perelló, A Balboa, M Perona, M Sans, A Salas, S Angulo, J Lloreta, R Benasayag, MA García-Gonzalez, M Pérez-Oliveras, J Coderch |
Scandinavian Journal of Gastroenterology | 2009 |
Joint analysis of individual participants’ data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index
C Huth, T Illig, C Herder, C Gieger, H Grallert, C Vollmert, W Rathmann, YH Hamid, O Pedersen, T Hansen, B Thorand, C Meisinger, A Döring, N Klopp, H Gohlke, W Lieb, C Hengstenberg, V Lyssenko, L Groop, H Ireland, JW Stephens, IW Asterholm, JO Jansson, H Boeing, M Möhlig, HM Stringham, M Boehnke, J Tuomilehto, JM Fernandez-Real, A Lopez-Bermejo, L Gallart, J Vendrell, SE Humphries, F Kronenberg, HE Wichmann, IM Heid |
Annals of Medicine | 2009 |
Immuno-Modulatory Gene Polymorphisms and Outcome in Breast and Ovarian Cancer
S Kim, A Hagemann, A DeMichele |
Immunological Investigations | 2009 |
Gene polymorphisms of TNF-α −308 (G/A), IL-10 −1082 (G/A), IL-6 −174 (G/C) and IL-1Ra (VNTR) in Egyptian cases with type 1 diabetes mellitus
A Settin, A Ismail, MA El-Magd, R El-Baz, A Kazamel |
Autoimmunity | 2009 |
Interleukin-6 promoter polymorphisms (-174 G/C) in Malaysian patients with systemic lupus erythematosus
KH Chua, BP Kee, SY Tan, LH Lian |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 2009 |
Association of interleukin-18 promoter polymorphisms with WHO pathological classes and serum IL-18 levels in Chinese patients with lupus nephritis
DY Chen, CW Hsieh, KS Chen, YM Chen, FJ Lin, JL Lan |
Lupus | 2009 |
Tumor Necrosis Factor-α −308 Genotypes Influence Inflammatory Activity and TNF-α Serum Concentrations in Children with Juvenile Idiopathic Arthritis
AF Mourão, J Caetano-Lopes, P Costa, H Canhão, MJ Santos, P Pinto, IV Brito, P Nicola, J Cavaleiro, J Teles, A Sousa, JM Gomes, J Branco, JO da COSTA, JG Pedro, MÁ de QUEIROZ, JE Fonseca |
The Journal of rheumatology | 2009 |
Functional Association of Interleukin 18 Gene −607 (C/A) Promoter Polymorphisms with Disease Course in Chinese Patients with Adult-onset Still’s Disease
DY Chen, YM Chen, HH Chen, CW Hsieh, CC Lin, JL Lan |
The Journal of rheumatology | 2009 |
Association of Interleukin-6 –174G>C Promoter Polymorphism with Risk of Cervical Cancer
R Gangwar, B Mittal, RD Mittal |
The International Journal of Biological Markers | 2009 |
Handbook on Immunosenescence
T Fulop, C Franceschi, K Hirokawa, G Pawelec |
2009 | |
Cytokine Polymorphisms in the Pathophysiology of Mood Disorders
M Clerici, B Arosio, E Mundo, E Cattaneo, S Pozzoli, B Dell'Osso, C Vergani, D Trabattoni, AC Altamura |
CNS Spectrums | 2009 |
Influence of proinflammatory cytokine gene polymorphism on childhood obesity
K Popko, E Górska, B Pyrzak, A Telmaszczyk-Emmel, A Wisniewska, A Majcher, M Wasik, U Demkow |
European Journal of Medical Research | 2009 |
Prognostic Significance of Interleukin-6 Single Nucleotide Polymorphism Genotypes in Neuroblastoma: rs1800795 (Promoter) and rs8192284 (Receptor)
JP Lagmay, WB London, TG Gross, A Termuhlen, N Sullivan, A Axel, B Mundy, M Ranalli, J Canner, P McGrady, B Hall |
Clinical cancer research | 2009 |
Insulin-like Growth Factor-1- and Interleukin-6-related Gene Variation and Risk of Multiple Myeloma: Table 1
BM Birmann, RM Tamimi, E Giovannucci, B Rosner, DJ Hunter, P Kraft, C Mitsiades, KC Anderson, GA Colditz |
Cancer epidemiology, biomarkers & prevention | 2009 |
Gene-gene interaction between CARD8 and interleukin-6 reduces Alzheimer's disease risk.
Fontalba A, Gutiérrez O, Llorca J, Mateo I, Vázquez-Higuera JL, Berciano J, Fernández-Luna JL, Combarros O |
Journal of Neurology | 2009 |
IL6 genotype and creatine kinase response to exercise.
Lappalainen J |
European Journal of Applied Physiology | 2009 |
Interleukin-6 haplotypes and the response to therapy of chronic hepatitis C virus infection.
Yee LJ, Im K, Borg B, Yang H, Liang TJ |
Genes and Immunity | 2009 |
The (-174) G/C polymorphism in the interleukin-6 gene is associated with risk of papillary thyroid carcinoma in Turkish patients.
Ozgen AG, Karadeniz M, Erdogan M, Berdeli A, Saygili F, Yilmaz C |
Journal of Endocrinological Investigation | 2009 |
Proinflammatory cytokine gene polymorphisms in irritable bowel syndrome.
Barkhordari E, Rezaei N, Ansaripour B, Larki P, Alighardashi M, Ahmadi-Ashtiani HR, Mahmoudi M, Keramati MR, Habibollahi P, Bashashati M, Ebrahimi-Daryani N, Amirzargar AA |
Journal of Clinical Immunology | 2009 |
Hematopoietic Stem Cell Transplantation
MR Bishop |
2008 | |
Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways
ML Slattery, RK Wolff, K Curtin, F Fitzpatrick, J Herrick, JD Potter, BJ Caan, WS Samowitz |
Mutation research | 2008 |
Making genomics functional: deciphering the genetics of acute lung injury
R Kamp, X Sun, JG Garcia |
Proceedings of the American Thoracic Society | 2008 |
Gene expression polymorphisms of interleukins-1 beta, -4, -6, -8, -10, and tumor necrosis factors-alpha, -beta: regression analysis of their effect upon oral squamous cell carcinoma.
Vairaktaris E, Yapijakis C, Serefoglou Z, Avgoustidis D, Critselis E, Spyridonidou S, Vylliotis A, Derka S, Vassiliou S, Nkenke E, Patsouris E |
Journal of Cancer Research and Clinical Oncology | 2008 |
Ambivalent aspects of interleukin-6 in cerebral ischemia: inflammatory versus neurotrophic aspects
S Suzuki, K Tanaka, N Suzuki |
Journal of Cerebral Blood Flow & Metabolism | 2008 |
Clinical Immunology
DB Kuhns |
Clinical Immunology | 2008 |
Type 1 diabetes: can exercise impair the autoimmune event? TheL-arginine/glutamine coupling hypothesis
MS Krause, PI de Bittencourt |
Cell Biochemistry and Function | 2008 |
Clinical Significance of Interleukin-6 (Il-6) Gene Polymorphism and Il-6 Serum Level in Pancreatic Adenocarcinoma and Chronic Pancreatitis
R Talar-Wojnarowska, A Gasiorowska, B Smolarz, H Romanowicz-Makowska, A Kulig, E Malecka-Panas |
Digestive Diseases and Sciences | 2008 |
Impact of cytokine gene polymorphisms on graft-vs-host disease
KA Markey, KP MacDonald, GR Hill |
Tissue Antigens | 2008 |
REVIEW ARTICLE: Cytokine Gene Polymorphisms in Recurrent Spontaneous Abortions: A Comprehensive Review
YK Choi, J Kwak-Kim |
American Journal of Reproductive Immunology | 2008 |
Association of interleukin-6 (−174G>C) promoter polymorphism with risk of squamous cell esophageal cancer and tumor location: An exploratory study
R Upadhyay, M Jain, S Kumar, UC Ghoshal, B Mittal |
Clinical Immunology | 2008 |
Inflammatory cytokine gene variants in coronary artery disease patients in Greece
A Manginas, A Tsiavou, A Chaidaroglou, G Giamouzis, D Degiannis, D Panagiotakos, DV Cokkinos |
Coronary Artery Disease | 2008 |
Giant cell arteritis and polymyalgia rheumatica: Role of cytokines in the pathogenesis and implications for treatment
VM Martinez-Taboada, L Alvarez, M RuizSoto, MJ Marin-Vidalled, M Lopez-Hoyos |
Cytokine | 2008 |
Influence of Cytokine Gene Polymorphisms on IgA Nephropathy
C Bantis, P Heering, S Aker, N Kuhr, B Grabensee, K Ivens |
Renal Failure | 2008 |
The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN studyboxs
J Shen, DK Arnett, P Pérez-Martínez, LD Parnell, CQ Lai, JM Peacock, JE Hixson, MY Tsai, RJ Straka, PN Hopkins, JM Ordovás |
Journal of lipid research | 2008 |
IL6 and IL1B Polymorphisms are Associated With Fat Mass in Older Men: The MrOS Study Sweden
L Strandberg, D Mellström, Ö Ljunggren, E Grundberg, MK Karlsson, AH Holmberg, ES Orwoll, AL Eriksson, J Svedberg, M Bengtsson, C Ohlsson, JO Jansson |
Obesity | 2008 |
Gene polymorphisms and pharmacogenetics in rheumatoid arthritis
I Rego-Pérez, M Fernández-Moreno, FJ Blanco |
Current genomics | 2008 |
Circulating prediagnostic interleukin-6 and C-reactive protein and prostate cancer incidence and mortality
JR Stark, H Li, P Kraft, T Kurth, EL Giovannucci, MJ Stampfer, J Ma, LA Mucci |
International Journal of Cancer | 2008 |
Zinc-gene interaction related to inflammatory/immune response in ageing
E Mocchegiani, M Malavolta |
Genes & Nutrition | 2008 |
Interleukin and interleukin receptor gene polymorphisms and susceptibility to melanoma
F Gu, AA Qureshi, T Niu, P Kraft, Q Guo, DJ Hunter, J Han |
Melanoma Research | 2008 |
Effect of cytokine and pharmacogenomic genetic polymorphisms in transplantation
DM Girnita, G Burckart, A Zeevi |
Current Opinion in Immunology | 2008 |
Cytokine gene polymorphisms and fatigue in breast cancer survivors: early findings
A Collado-Hidalgo, JE Bower, PA Ganz, MR Irwin, SW Cole |
Brain, Behavior, and Immunity | 2008 |
An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients
DP Ng, S Nurbaya, SH Ye, AS Krolewski |
Kidney International | 2008 |
Common studied polymorphisms do not affect plasma cytokine levels upon endotoxin exposure in humans
S Taudorf, KS Krabbe, RM Berg, K Møller, BK Pedersen, H Bruunsgaard |
Clinical & Experimental Immunology | 2008 |
Neuroendocrine-immune mechanisms of behavioral comorbidities in patients with cancer
AH Miller, S Ancoli-Israel, JE Bower, L Capuron, MR Irwin |
Journal of Clinical Oncology | 2008 |
Common interleukin-6 promoter variants associate with the more severe forms of distal interphalangeal osteoarthritis
OP Kämäräinen, S Solovieva, T Vehmas, K Luoma, H Riihimäki, L Ala-Kokko, M Männikkö, P Leino-Arjas |
Arthritis Research & Therapy | 2008 |
Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk
ML Slattery, K Curtin, C Sweeney, RK Wolff, RN Baumgartner, KB Baumgartner, AR Giuliano, T Byers |
Obesity (Silver Spring, Md.) | 2008 |
Clone-specific expression, transcriptional regulation, and action of interleukin-6 in human colon carcinoma cells
W Brozek, G Bises, G Fabjani, HS Cross, M Peterlik |
BMC Cancer | 2008 |
Abatacept in difficult-to-treat juvenile idiopathic arthritis
JB Kuemmerle-Deschner, S Benseler |
Biologics : targets & therapy | 2008 |
Biological therapies for the treatment of juvenile idiopathic arthritis: Lessons from the adult and pediatric experiences
ML Stoll, AC Gotte |
Biologics : targets & therapy | 2008 |
The interleukin-6-174 G/C promoter polymorphism and arterial stiffness; the Rotterdam Study
MP Sie, FU Mattace-Raso, AG Uitterlinden, PP Arp, A Hofman, HA Pols, AP Hoeks, RS Reneman, R Asmar, CM van Duijn, JC Witteman |
Vascular Health and Risk Management | 2008 |
Psychoneuroimmunology
F Tausk, I Elenkov, J Moynihan |
Dermatologic Therapy | 2008 |
Association of cytokine gene polymorphisms in CWP and its severity in Turkish coal workers
I Ates, HS Suzen, B Yucesoy, IO Tekin, A Karakaya |
American Journal of Industrial Medicine | 2008 |
Interleukin-6 (IL-6), Tumor Necrosis Factor-α (TNF-α) Levels and IL-6, TNF-Polymorphisms in Children With Thrombosis
S Unal, F Gumruk, S Aytac, D Yalnzoglu, A Gurgey |
Journal of Pediatric Hematology/Oncology | 2008 |
Ability of epistatic interactions of cytokine single‐nucleotide polymorphisms to predict susceptibility to disease subsets in systemic sclerosis patients
L Beretta, F Cappiello, JH Moore, M Barili, CS Greene, R Scorza |
Arthritis & Rheumatism | 2008 |
Contribution of Gender-Specific Genetic Factors to Osteoporosis Risk
D Karasik, SL Ferrari |
Annals of Human Genetics | 2008 |
Cytokine gene polymorphism in kidney transplantation — Impact of TGF-β1, TNF-α and IL-6 on graft outcome
PN Nikolova, MI Ivanova, SM Mihailova, AP Myhailova, DN Baltadjieva, PL Simeonov, EK Paskalev, EJ Naumova |
Transplant Immunology | 2008 |
Cancer Immunology
OJ Finn |
New England Journal of Medicine | 2008 |
Inflammatory cytokines in juvenile idiopathic arthritis: Effects on physical growth and the insulin-like-growth factor axis
SC Wong, VE MacRae, JA Gracie, IB McInnes, P Galea, J Gardner-Medwin, SF Ahmed |
Growth Hormone & IGF Research | 2008 |
Association of IL-6 gene polymorphisms and COPD in a Spanish Population
E Córdoba-Lanús, JP de-Torres, C López-Aguilar, MC Rodríguez-Pérez, N Maca-Meyer, A Montejo-de-Garcini, A Aguirre-Jaime, L Pérez-Méndez, C Casanova |
Respiratory Medicine | 2008 |
Association between genetic variants of IL-1β, IL-6 and TNF-α cytokines and cognitive performance in the elderly general population of the MEMO-study
BT Baune, G Ponath, M Rothermundt, O Riess, H Funke, K Berger |
Psychoneuroendocrinology | 2008 |
Polymorphisms of cytokine and innate immunity genes and GVHD
AM Dickinson, E Holler |
Best Practice & Research Clinical Haematology | 2008 |
Multiple Organ Dysfunction Syndrome in Children With Sepsis: Role of Genetic Factors
O Liangos, BL Jaber |
Seminars in Nephrology | 2008 |
Is the interleukin-6 haplotype a prognostic factor for sciatica?
J Karppinen, I Daavittila, N Noponen, M Haapea, S Taimela, H Vanharanta, L Ala-Kokko, M Männikkö |
European Journal of Pain | 2008 |
Association of Interleukin-6 Gene Polymorphisms with Bone Mineral Density in Mexican Women
JJ Magaña, R Gómez, B Cisneros, L Casas, M Valdés-Flores |
Archives of Medical Research | 2008 |
Polymorphisms of the Interleukin-6 Gene Promoter and Abdominal Aortic Aneurysm
L Smallwood, R Allcock, F Bockxmeer, N Warrington, LJ Palmer, B Iacopetta, PE Norman |
European Journal of Vascular and Endovascular Surgery | 2008 |
Genetic polymorphisms and the fate of the transplanted organ
B Krüger, B Schröppel, BT Murphy |
Transplantation Reviews | 2008 |
Selected markers of cardiovascular disease in a population exposed to arsenic from drinking water
Z Bošnjak, S Ćavar, T Klapec, M Milić, M Klapec-Basar, M Toman |
Environmental Toxicology and Pharmacology | 2008 |
Clinical Impact of Cytokine and Growth Factor Genetic Polymorphisms in Thoracic Organ Transplantation
DM Girnita, SA Webber, A Zeevi |
Clinics in Laboratory Medicine | 2008 |
The Impact of Immune Gene Polymorphisms in Kidney and Liver Transplantation
P Nickerson |
Clinics in Laboratory Medicine | 2008 |
Surveillance biologique des patients transplantés rénaux : vers une prévision des complications associées à l’immunosuppression ?
P Saas, C Courivaud, J Bamoulid, F Garnache-Ottou, E Seilles, D Ducloux |
Annales Pharmaceutiques Françaises | 2008 |
A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population
A Benrick, P Jirholt, I Wernstedt, M Gustafsson, J Scheller, AL Eriksson, J Borén, T Hedner, C Ohlsson, T Härd, S Rose-John, JO Jansson |
Regulatory Peptides | 2008 |
Interleukin 6 −174(G>C) gene polymorphism is related to celiac disease and autoimmune thyroiditis coincidence in diabetes type 1 children
M Myśliwiec, J Myśliwska, K Zorena, A Balcerska, E Malinowska, P Wiśniewski |
Diabetes Research and Clinical Practice | 2008 |
Synergistic effects of the polymorphisms in the PAI-1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease
B Sarecka, I Zak, J Krauze |
Clinical Biochemistry | 2008 |
Molecular epidemiology, cancer-related symptoms, and cytokines pathway
CC Reyes-Gibby, X Wu, M Spitz, R Kurzrock, M Fisch, E Bruera, S Shete |
The Lancet Oncology | 2008 |
Cerebral Small Vessel Disease: Genetic Risk Assessment for Prevention and Treatment
A Lam, MA Hamilton-Bruce, J Jannes, SA Koblar |
Molecular diagnosis & therapy | 2008 |
IL-6 as a biomarker of ischemic cerebrovascular disease
VP Moreno, D Subirá, E Meseguer, P Llamas |
Biomarkers in Medicine | 2008 |
Interleukin-6 Polymorphism is Associated with Chorioamnionitis and Neonatal Infections in Preterm Infants
M Reiman, H Kujari, E Ekholm, H Lapinleimu, L Lehtonen, L Haataja |
The Journal of Pediatrics | 2008 |
Interactions of interleukin-6 gene polymorphisms with calcium intake and physical activity on bone mass in pre-menarche Chinese girls
X Li, GP He, B Zhang, YM Chen, YX Su |
Osteoporosis International | 2008 |
IL6 (-174) and TNFA (-308) promoter polymorphisms are associated with systemic creatine kinase response to eccentric exercise
C Yamin, JA Duarte, JM Oliveira, O Amir, M Sagiv, N Eynon, M Sagiv, RE Amir |
European Journal of Applied Physiology | 2008 |
Vorstellungen zur Pathogenese der juvenilen idiopathischen Arthritis
T Niehues, O Feyen, T Telieps |
Zeitschrift für Rheumatologie | 2008 |
Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment
SJ Bull, P Huezo-Diaz, EB Binder, JF Cubells, G Ranjith, C Maddock, C Miyazaki, N Alexander, M Hotopf, AJ Cleare, S Norris, E Cassidy, KJ Aitchison, AH Miller, CM Pariante |
Molecular Psychiatry | 2008 |
IL6 gene-wide haplotype is associated with susceptibility to acute lung injury
C Flores, SF Ma, K Maresso, MS Wade, J Villar, JG Garcia |
Translational Research | 2008 |
Serum Interleukin-6 Levels, Not Genotype, Correlate With Coronary Plaque Complexity
LT Kuo, NI Yang, WJ Cherng, S Verma, MJ Hung, SY Wang, M Liu, S Chen, CH Wang |
International Heart Journal | 2008 |
Identification of a novel regulatory region in the interleukin-6 gene promoter
JM Samuel, D Kelberman, AJ Smith, SE Humphries, P Woo |
Cytokine | 2008 |
Genetic Polymorphisms Impact the Risk of Acute Rejection in Pediatric Heart Transplantation: A Multi-Institutional Study:
DM Girnita, MM Brooks, SA Webber, GJ Burckart, R Ferrell, G Zdanowicz, S DeCroo, L Smith, R Chinnock, C Canter, L Addonizio, D Bernstein, JK Kirklin, S Ranganathan, D Naftel, AL Girnita, A Zeevi |
Transplantation | 2008 |
Cytokine gene polymorphisms and cytokine levels in pulmonary tuberculosis
P Selvaraj, K Alagarasu, M Harishankar, M Vidyarani, DN Rajeswari, PR Narayanan |
Cytokine | 2008 |
Genetic variants of IL6 gene promoter influence on C-reactive protein levels but are not associated with susceptibility to invasive pulmonary aspergillosis in haematological patients
J Sainz, E Pérez, S Gómez-Lopera, E López-Fernández, L Moratalla, S Oyonarte, M Jurado |
Cytokine | 2008 |
Correlation between interleukin-6 promoter and C-reactive protein (CRP) polymorphisms and CRP levels with the Mainz Severity Score Index for Fabry disease
G Altarescu, G Chicco, C Whybra, S Delgado-Sanchez, N Sharon, M Beck, D Elstein |
Journal of Inherited Metabolic Disease | 2008 |
A familial analysis of aggressive periodontitis - clinical and genetic findings
L Nibali, N Donos, PM Brett, M Parkar, T Ellinas, M Llorente, GS Griffiths |
Journal of Periodontal Research | 2008 |
Interleukin-6-174 Genotype, Periodontal Disease and Adverse Pregnancy Outcomes: A Pilot Study
M Dashash, J Nugent, P Baker, D Tansinda, F Blinkhorn |
Journal of Clinical Immunology | 2008 |
Comprehensive association study of genetic variants in the IL-1 gene family in systemic juvenile idiopathic arthritis
CJ Stock, EM Ogilvie, JM Samuel, M Fife, CM Lewis, P Woo |
Genes and Immunity | 2008 |
Association of IL-6 gene polymorphism with the outcome of allogeneic haematopoietic stem cell transplantation in Czech patients
Z Ambruzova, F Mrazek, L Raida, E Faber, J Onderkova, E Kriegova, K Indrak, M Petrek |
International Journal of Immunogenetics | 2008 |
Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis
CJ Nile, RC Read, M Akil, GW Duff, AG Wilson |
Arthritis & Rheumatism | 2008 |
‘Deep phenotyping’: characterizing populations in the era of genomics and systems biology:
RP Tracy |
Current Opinion in Lipidology | 2008 |
Do inflammatory cytokine genes confer susceptibility to diabetic nephropathy?
S Maeda |
Kidney International | 2008 |
Association between −174 G/C Promoter Polymorphism of the Interleukin-6 Gene and Progression of Prostate Cancer in North Indian Population
P Kesarwani, DK Ahirwar, A Mandhani, RD Mittal |
DNA and Cell Biology | 2008 |
The -1082 interleukin-10 polymorphism is associated with acute respiratory failure after major trauma: A prospective cohort study
O Schroeder, KM Schulte, J Schroeder, A Ekkernkamp, RA Laun |
Surgery | 2008 |
Comparison of serum levels of inflammatory markers and allelic variant of interleukin-6 in patients with acute coronary syndrome and stable angina pectoris:
O Ozdemir, F Gundogdu, S Karakelleoglu, S Sevimli, I Pirim, M Acikel, S Arslan, S Serdar |
Coronary Artery Disease | 2008 |
Cytokine Gene Polymorphisms in Heavy Drinkers With and Without Decompensated Liver Disease: A Case-Control Study
D Gleeson, MP Bradley, J Jones, RJ Peck, SK Bond, MD Teare, GW Duff |
The American Journal of Gastroenterology | 2008 |
Association of interleukin-6 (IL-6) haplotypes with plaque-induced gingivitis in children
LI Holla, K Musilova, J Vokurka, L Klapusová, P Pantuckova, M Kukletova, L Kukla, V Znojil |
Acta Odontologica Scandinavica | 2008 |
Non-HLA genetics and predicting outcome in HSCT
AM Dickinson |
International Journal of Immunogenetics | 2008 |
Interleukin-6 gene variation in Spanish patients with immunoglobulin-A deficiency
R López-Mejías, A Martínez, N Pozo, M Fernández-Arquero, A Ferreira, E Urcelay, G Fontán, EG de la Concha, C Núñez |
Human Immunology | 2008 |
A critical assessment of adverse pregnancy outcome and periodontal disease
G Wimmer, BL Pihlstrom |
Journal of Clinical Periodontology | 2008 |
Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study
U Vogel, J Christensen, H Wallin, S Friis, BA Nexø, O Raaschou-Nielsen, K Overvad, A Tjønneland |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2008 |
Genetic association of cytokine DNA polymorphisms with head and neck cancer
Z Serefoglou, C Yapijakis, E Nkenke, E Vairaktaris |
Oral Oncology | 2008 |
Association of Interleukin 6 Promoter Polymorphism (-174G/C) with IL-6 Level and Outcome in Severe Sepsis
O Sabeļnikovs, L Ñikitina-Zaķe, I Vanags |
Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences | 2008 |
Cytokine gene polymorphisms in periodontal disease: a meta-analysis of 53 studies including 4178 cases and 4590 controls
GK Nikolopoulos, NL Dimou, SJ Hamodrakas, PG Bagos |
Journal of Clinical Periodontology | 2008 |
Interleukin promoter polymorphisms and prognosis in colorectal cancer
S Wilkening, B Tavelin, F Canzian, K Enquist, R Palmqvist, A Altieri, G Hallmans, K Hemminki, P Lenner, A Forsti |
Carcinogenesis | 2008 |
Correlation between polymorphisms at interleukin-6 but not at interleukin-10 promoter and the risk of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis in Brazilian individuals
SR Gadelha, LC Alcântara, GC Costa, AX Acosta, D Rios, S Kashima, DT Covas, B Galvão-Castro |
Journal of Medical Virology | 2008 |
TNF, IFNG, IL6, IL10 and TGFB1 gene polymorphisms in South and Southeast Brazil
JE Visentainer, AM Sell, GC da Silva, AD Cavichioli, DS Franceschi, SR Lieber, CA de Souza |
International Journal of Immunogenetics | 2008 |
Vaccination, a human model of inflammation, activates systemic inflammation but does not trigger proinflammatory gene expression in adipose tissue
M Ekström, P Eriksson, P Tornvall |
Journal of Internal Medicine | 2008 |
Lack of Associations Between Several Polymorphisms in Cytokine Genes and the Risk of Chronic Obstructive Pulmonary Diseases in Taiwan
MH Hsieh, IW Chong, JJ Hwang, CH Lee, CK Ho, ML Yu, CT Huang, CY Lee, MT Wu, DC Christiani |
The Kaohsiung Journal of Medical Sciences | 2008 |
Gene expression polymorphisms of interleukins-1β, -4, -6, -8, -10, and tumor necrosis factors-α, -β: regression analysis of their effect upon oral squamous cell carcinoma
E Vairaktaris, C Yapijakis, Z Serefoglou, D Avgoustidis, E Critselis, S Spyridonidou, A Vylliotis, S Derka, S Vassiliou, E Nkenke, E Patsouris |
Journal of Cancer Research and Clinical Oncology | 2008 |
The interleukin-6 gene and critical illness: Is inflammatory gene variation the key to personalized medicine in the intensive care unit?*:
JD Christie |
Critical Care Medicine | 2008 |
Interleukin-6 Polymorphisms Are Associated With Pathogenic Bacteria in Subjects With Periodontitis
L Nibali, MS Tonetti, D Ready, M Parkar, PM Brett, N Donos, F D'Aiuto |
Journal of Periodontology | 2008 |
Transforming growth factor- 1 869T/C, but not interleukin-6 -174G/C, polymorphism associates with hypertension in rheumatoid arthritis
VF Panoulas, KM Douglas, JP Smith, A Stavropoulos-Kalinoglou, GS Metsios, P Nightingale, GD Kitas |
Rheumatology | 2008 |
Evaluation of serum resistin levels in patients with ocular and non-ocular Behçet’s disease
FN Yalçindag, A Yalçindag, F Batioglu, O Çaglayan, Ü Kisa, Ö Özdemir |
Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie | 2008 |
Association between the -174 G/C promoter polymorphism of the interleukin-6 gene and cardiovascular disease risk factors in Brazilian older women
AC Tonet, M Karnikowski, CF Moraes, L Gomes, MG Karnikowski, C Córdova, OT Nóbrega |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 2008 |
Interleukin-6 (IL-6) and receptor (IL6-R) gene haplotypes associate with amniotic fluid protein concentrations in preterm birth
DR Velez, SJ Fortunato, SM Williams, R Menon |
Human Molecular Genetics | 2008 |
The effect of IL6 -174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN study
J Shen, DK Arnett, P Pérez-Martínez, LD Parnell, CQ Lai, JM Peacock, JE Hixson, MY Tsai, RJ Straka, PN Hopkins, JM Ordovás |
Journal of lipid research | 2008 |
Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
BK Pedersen, MA Febbraio |
Physiological reviews | 2008 |
Biomarkers of Inflammation and MRI-Defined Small Vessel Disease of the Brain: The Cardiovascular Health Study
M Fornage, YA Chiang, ES O'Meara, BM Psaty, AP Reiner, DS Siscovick, RP Tracy, WT Longstreth |
Stroke; a journal of cerebral circulation | 2008 |
Imunossenescência: a relação entre leucócitos, citocinas e doenças crônicas
AC Tonet, O de Tolêdo Nóbrega |
Revista Brasileira de Geriatria e Gerontologia | 2008 |
Polymorphisms Cyclooxygenase-2 -765G>C and Interleukin-6 -174G>C Are Associated with Serum Inflammation Markers in a High Cardiovascular Risk Population and Do Not Modify the Response to a Mediterranean Diet Supplemented with Virgin Olive Oil or Nuts
D Corella, JI González, M Bulló, P Carrasco, O Portolés, J Díez-Espino, MI Covas, V Ruíz-Gutierrez, E Gómez-Gracia, F Arós, M Fiol, MC Herrera, JM Santos, G Sáez, R Lamuela, C Lahoz, E Vinyoles, E Ros, R Estruch |
The Journal of nutrition | 2008 |
A comprehensive review of the genetics of juvenile idiopathic arthritis
S Prahalad, DN Glass |
Pediatric Rheumatology | 2008 |
Primer on the Rheumatic Diseases
JH Klippel, JH Stone, LJ Crofford, PH White |
2008 | |
Infectious Diseases in the Pediatric Intensive Care Unit
S Nadel |
2008 | |
Association of Serum Interleukin-6 Concentration with a Functional IL6 −6331T>C Polymorphism
AJ Smith, F DAiuto, J Palmen, JA Cooper, J Samuel, S Thompson, J Sanders, N Donos, L Nibali, D Brull, P Woo, SE Humphries |
Clinical chemistry | 2008 |
The Influence of Tumor Necrosis Factor-α −308 G/A and IL-6 −174 G/C on Pain and Analgesia Response in Lung Cancer Patients Receiving Supportive Care
CC Reyes-Gibby, BE Osta, MR Spitz, H Parsons, R Kurzrock, X Wu, S Shete, E Bruera |
Cancer epidemiology, biomarkers & prevention | 2008 |
Correlation between interleukin-6 promoter and C-reactive protein (CRP) polymorphisms and CRP levels with the Mainz Severity Score Index for Fabry disease.
Altarescu G, Chicco G, Whybra C, Delgado-Sanchez S, Sharon N, Beck M, Elstein D |
Journal of Inherited Metabolic Disease | 2008 |
Interleukin-6 -174 genotype, periodontal disease and adverse pregnancy outcomes: a pilot study.
Dashash M, Nugent J, Baker P, Tansinda D, Blinkhorn F |
Journal of Clinical Immunology | 2008 |
Pathophysiology of acute graft-versus-host disease: recent advances
Y Sun, I Tawara, T Toubai, P Reddy |
Translational Research | 2007 |
IL6 genotypes and colon and rectal cancer
ML Slattery, RK Wolff, JS Herrick, BJ Caan, JD Potter |
Cancer causes & control : CCC | 2007 |
Advances in the understanding of acute graft- versus -host disease: Review
ES Morris, GR Hill |
British Journal of Haematology | 2007 |
Gene Polymorphisms of TNF-α−308, IL-10−1082, IL-6−174, and IL-1RaVNTR Related to Susceptibility and Severity of Rheumatic Heart Disease
A Settin, H Abdel-Hady, R El-Baz, I Saber |
Pediatric Cardiology | 2007 |
Juvenile rheumatoid arthritis
DS Kim |
Korean Journal of Pediatrics | 2007 |
Obesity and polymorphisms in genes regulating human adipose tissue
I Dahlman, P Arner |
International Journal of Obesity | 2007 |
Association of interleukin-6 and interleukin-10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status
I Marinou, J Healy, D Mewar, DJ Moore, MC Dickson, MH Binks, DS Montgomery, K Walters, AG Wilson |
Arthritis & Rheumatism | 2007 |
Juvenile idiopathic arthritis
A Ravelli, A Martini |
The Lancet | 2007 |
Haematopoietic stem cell transplantation: can our genes predict clinical outcome?
AM Dickinson, JL Harrold, H Cullup |
Expert Reviews in Molecular Medicine | 2007 |
Genetic susceptibility to total hip arthroplasty failure: a preliminary study on the influence of matrix metalloproteinase 1, interleukin 6 polymorphisms and vitamin D receptor
MH Malik, F Jury, A Bayat, WE Ollier, PR Kay |
Annals of the rheumatic diseases | 2007 |
Interleukin-6 expression and gene polymorphism are associated with severity of periodontal disease in a sample of Brazilian individuals
PR Moreira, PM Lima, KO Sathler, SA Imanishi, JE Costa, RS Gomes, KJ Gollob, WO Dutra |
Clinical & Experimental Immunology | 2007 |
The impact of interleukin-6 promoter -597/-572/-174genotype on interleukin-6 production after lipopolysaccharide stimulation
M Müller-Steinhardt, B Ebel, C Härtel |
Clinical & Experimental Immunology | 2007 |
Genetic susceptibility to lymphoma
CF Skibola, JD Curry, A Nieters |
Haematologica | 2007 |
Association of cytokine gene polymorphism with susceptibility and clinical types of leprosy
A Settin, S Nassar, A Abdel-Latif, R Elbaz, S El-Mongy, A Hassan, A Hassan |
International journal of health sciences | 2007 |
Alcohol consumption, interleukin-6 and apolipoprotein E genotypes, and concentrations of interleukin-6 and serum amyloid P in older adults
KJ Mukamal, NS Jenny, RP Tracy, DS Siscovick |
The American journal of clinical nutrition | 2007 |
Personalized Nutrition: Nutritional Genomics as a Potential Tool for Targeted Medical Nutrition Therapy
S Vakili, MA Caudill |
Nutrition Reviews | 2007 |
Investigation of functional gene polymorphisms interleukin-1β, interleukin-6, interleukin-10 and tumor necrosis factor in individuals with oral lichen planus
GM Xavier, AR de Sá, AL Guimarães, TA da Silva, RS Gomez |
Journal of Oral Pathology & Medicine | 2007 |
Influence of cytokine genes polymorphisms on long-term outcome in renal transplantation
B Breulmann, C Bantis, M Siekierka, C Blume, S Aker, N Kuhr, B Grabensee, K Ivens |
Clinical Transplantation | 2007 |
The role of interleukin-6 in insulin resistance, body fat distribution and energy balance
M Hoene, C Weigert |
Obesity Reviews | 2007 |
Genetic variation in the interleukin-6 gene in relation to risk and outcomes in acute coronary syndrome
A Mälarstig, L Wallentin, A Siegbahn |
Thrombosis Research | 2007 |
The IL6 −174G/C polymorphism and sudden infant death syndrome
SH Opdal, TO Rognum |
Human Immunology | 2007 |
Risk assessment in haematopoietic stem cell transplantation: Pre–transplant patient and donor factors: non-HLA genetics
AM Dickinson |
Best Practice & Research Clinical Haematology | 2007 |
Interleukin-6 Polymorphisms, Helicobacter pylori Infection in Adult Brazilian Patients with Chronic Gastritis and Gastric Adenocarcinoma
LL Gatti, RR Burbano, M Zambaldi-Tunes, RW de-Lábio, PP de Assumpção, MA Cardoso-Smith, SL Marques-Payão |
Archives of Medical Research | 2007 |
Interleukin-6 gene variants and the risk of sepsis development in children
J Michalek, P Svetlikova, M Fedora, M Klimovic, L Klapacova, D Bartosova, H Hrstkova, JA Hubacek |
Human Immunology | 2007 |
Efficacy of thalidomide in systemic onset juvenile rheumatoid arthritis
M García-Carrasco, S Fuentes-Alexandro, RO Escárcega, J Rojas-Rodriguez, LE Escobar |
Joint Bone Spine | 2007 |
Interleukin-6 gene polymorphism and faster progression to end-stage renal failure in chronic glomerulonephritis
M Buraczynska, L Jozwiak, P Ksiazek, E Borowicz, P Mierzicki |
Translational Research | 2007 |
Impact of serum levels and gene polymorphism of cytokines on chronic hepatitis C infection
TY Chen, YS Hsieh, TT Wu, SF Yang, CJ Wu, GJ Tsay, HL Chiou |
Translational Research | 2007 |
IL-6-174 C/G polymorphism in the gastroenteropancreatic neuroendocrine tumors (GEP-NETs)
MC Berković, M Jokić, J Marout, S Radošević, V Zjačić-Rotkvić, S Kapitanović |
Experimental and Molecular Pathology | 2007 |
Handbook of Systemic Autoimmune Diseases
M Karmegam, RJ Quigg |
Handbook of Systemic Autoimmune Diseases | 2007 |
Common genetic factors for depression and cardiovascular disease
B Bondy |
Dialogues in clinical neuroscience | 2007 |
Sepsis
JM O’Brien, NA Ali, SK Aberegg, E Abraham |
The American Journal of Medicine | 2007 |
Systemic onset juvenile idiopathic arthritis: update on pathogenesis and treatment
LJ Mirkinson, IM Katona |
Expert Review of Clinical Immunology | 2007 |
Effect of the interleukin-6 C174G gene polymorphism on treatment of acute and chronic hepatitis C in human immunodeficiency virus coinfected patients
J Nattermann, M Vogel, T Berg, M Danta, B Axel, C Mayr, R Bruno, C Tural, G Klausen, B Clotet, T Lutz, F Grünhage, M Rausch, HD Nischalke, K Schewe, B Bienek, G Haerter, T Sauerbruch, JK Rockstroh, U Spengler, |
Hepatology | 2007 |
Arthrites juvéniles idiopathiques
C Job-Deslandre |
EMC - Appareil locomoteur | 2007 |
No evidence for a role of the proximal IL-6 G/C -174 single nucleotide polymorphism in Italian patients with systemic sclerosis
L Beretta, A Santaniello, F Cappiello, M Barili, R Scorza |
Journal of Cellular and Molecular Medicine | 2007 |
Association of interleukin (IL)-4 intron-3 and IL-6 −174 G/C gene polymorphism with susceptibility to end-stage renal disease
RD Mittal, PK Manchanda |
Immunogenetics | 2007 |
Interleukin-6 and atrial fibrillation in patients with coronary artery disease: data from the Heart and Soul Study
GM Marcus, MA Whooley, DV Glidden, L Pawlikowska, JG Zaroff, JE Olgin |
American Heart Journal | 2007 |
Cytokine gene variants and venous thrombotic risk in the BRATROS (BRAZILIAN THROMBOSIS STUDY)
F Pieroni, DM Lourenço, VM Morelli, FH Maffei, MA Zago, RF Franco |
Thrombosis Research | 2007 |
Interleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal Muscle
S Glund, A Deshmukh, YC Long, T Moller, HA Koistinen, K Caidahl, JR Zierath, A Krook |
Diabetes | 2007 |
Impact of Common Type 2 Diabetes Risk Polymorphisms in the DESIR Prospective Study
M Vaxillaire, J Veslot, C Dina, C Proenca, S Cauchi, G Charpentier, J Tichet, F Fumeron, M Marre, D Meyre, B Balkau, P Froguel |
Diabetes | 2007 |
Frequency distribution of cytokine gene polymorphisms in the healthy North Indian population
G Kaur, CC Rapthap, N Kumar, S Kumar, S Neolia, NK Mehra |
Tissue Antigens | 2007 |
Cytokine gene polymorphism and progression of renal and cardiovascular diseases
M Rao, C Wong, P Kanetsky, M Girndt, P Stenvinkel, M Reilly, DS Raj |
Kidney International | 2007 |
No association of interleukin-6 gene polymorphism (-174 G/C) with premature coronary artery disease in a Turkish cohort:
C Sekuri, FS Cam, A Sagcan, E Ercan, I Tengiz, E Alioglu, A Berdeli |
Coronary Artery Disease | 2007 |
Interleukin-6 gene promoter –174G/C polymorphism and insulin resistance: a pilot study
P Tretjakovs, G Latkovskis, N Licis, D Juhnevica, A Jurka, I Bormane, JI Aivars, A Stifts, V Pirags |
Clinical Chemistry and Laboratory Medicine | 2007 |
Long-term prognosis after coronary bypass surgery depends on interleukin 6 polymorphism and past acute infections
J Myśliwska, J Więckiewicz, Ł Hak, J Siebert, J Rogowski, K Szyndler, A Myśliwski |
International Journal of Cardiology | 2007 |
The extent of periodontal disease and the IL-6 −174 genotype as determinants of serum IL-6 level
T Raunio, M Nixdorf, M Knuuttila, R Karttunen, O Vainio, T Tervonen |
Journal of Clinical Periodontology | 2007 |
Association between plasma IL-6, the IL6 −174G>C gene variant and the metabolic syndrome in type 2 diabetes mellitus
JW Stephens, SJ Hurel, GD Lowe, A Rumley, SE Humphries |
Molecular Genetics and Metabolism | 2007 |
Genetic Polymorphisms of Inflammatory Cytokines and Liver Fibrosis Progression Due To Recurrent Hepatitis C
E Falleti, C Fabris, P Toniutto, E Fontanini, A Cussigh, M Caldato, E Rossi, D Bitetto, R Minisini, C Smirne, M Pirisi |
Journal of Interferon & Cytokine Research | 2007 |
Autoinflammatory syndromes with a dermatological perspective
N KANAZAWA, F FURUKAWA |
The Journal of Dermatology | 2007 |
Association of polymorphisms of cytokine genes (IL1B, IL1RN, TNFA, LTA, IL6, IL8, and IL10) with chronic obstructive pulmonary disease
KV Danilko, GF Korytyna, LZ Akhmadishina, DG Yanbaeva, SZ Zagidullin, TV Victorova |
Molecular Biology | 2007 |
Polymorphisms in cytokine genes influence long-term survival differently in elderly male and female patients
T Cederholm, M Persson, P Andersson, P Stenvinkel, L Nordfors, J Madden, I Vedin, B Wretlind, RF Grimble, J Palmblad |
Journal of Internal Medicine | 2007 |
CARDIOVASCULAR AND SURVIVAL PARADOXES IN DIALYSIS PATIENTS: Genetics and Reverse Epidemiology Among Patients on Chronic Hemodialysis: REVERSE EPIDEMIOLOGY AMONG PATIENTS ON CHRONIC HEMODIALYSIS
VS Balakrishnan, M Rao |
Seminars in Dialysis | 2007 |
Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes
U Vogel, J Christensen, H Wallin, S Friis, BA Nexø, A Tjønneland |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2007 |
Pro-inflammatory genetic profiles in subjects with peripheral arterial occlusive disease and critical limb ischemia
A Flex, E Gaetani, F Angelini, A Sabusco, C Chillà, G Straface, F Biscetti, P Pola, JJ Castellot, R Pola |
Journal of Internal Medicine | 2007 |
Biomarkers for cancer cachexia: is there also a genetic component to cachexia?
BH Tan, DA Deans, RJ Skipworth, JA Ross, KC Fearon |
Supportive Care in Cancer | 2007 |
IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study
JD Walston, MD Fallin, M Cushman, L Lange, B Psaty, N Jenny, W Browner, R Tracy, P Durda, A Reiner |
Human Genetics | 2007 |
Association of CD14, IL1B, IL6, IL10 and TNFA functional gene polymorphisms with symptomatic dental abscesses
AR de Sá, PR Moreira, GM Xavier, I Sampaio, E Kalapothakis, WO Dutra, RS Gomez |
International Endodontic Journal | 2007 |
TNF-alpha, TNF-beta, IL-6, IL-10, PECAM-1 and the MPO Inflammatory Gene Polymorphisms in Osteosarcoma:
ID Oliveira, AS Petrilli, MH Tavela, MA Zago, SR de Toledo |
Journal of Pediatric Hematology/Oncology | 2007 |
Specific gene expression profiles in systemic juvenile idiopathic arthritis
EM Ogilvie, A Khan, M Hubank, P Kellam, P Woo |
Arthritis & Rheumatism | 2007 |
Role of IL-6, TNF-A and LT-A variants in the modulation of the clinical expression of plaque-induced gingivitis
C Scapoli, E Mamolini, L Trombelli |
Journal of Clinical Periodontology | 2007 |
Interleukin 6 Variable Number of Tandem Repeats (VNTR) Gene Polymorphism in Centenarians
C Capurso, V Solfrizzi, A D'Introno, AM Colacicco, SA Capurso, C Semeraro, A Capurso, F Panza |
Annals of Human Genetics | 2007 |
Investigation of functional gene polymorphisms: IL-1B, IL-6 and TNFA in benign migratory glossitis in Brazilian individuals: Cytokine gene polymorphisms and benign migratory glossitis
AL Guimarães, JF Correia-Silva, MG Diniz, GM Xavier, MC Horta, RS Gomez |
Journal of Oral Pathology & Medicine | 2007 |
Single nucleotide polymorphisms of cytokine genes in the healthy Slovak population
J Javor, M Bucova, S Ferencik, H Grosse-Wilde, M Buc |
International Journal of Immunogenetics | 2007 |
Polymorphisms in the CD14 and IL-6 genes associated with periodontal disease
T Tervonen, T Raunio, M Knuuttila, R Karttunen |
Journal of Clinical Periodontology | 2007 |
Prospective study of interaction between alcohol, NSAID use and polymorphisms in genes involved in the inflammatory response in relation to risk of colorectal cancer
U Vogel, J Christensen, M Dybdahl, S Friis, RD Hansen, H Wallin, BA Nexø, O Raaschou-Nielsen, PS Andersen, K Overvad, A Tjønneland |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2007 |
Interleukin-6 −174 promoter polymorphism does not influence IL-6 production after LPS and IL-1β stimulation in human umbilical cord vein endothelial cells
P Kiszel, V Makó, Z Prohászka, L Cervenak |
Cytokine | 2007 |
Influence of the IL-6 −572C>G polymorphism on inflammatory markers according to cigarette smoking in Korean healthy men
KK Shin, Y Jang, SJ Koh, JS Chae, OY Kim, S Park, D Choi, DJ Shin, HJ Kim, JH Lee |
Cytokine | 2007 |
Efficacité de la thalidomide dans les arthrites chroniques juvéniles à début systémique
M García-Carrasco, S Fuentes-Alexandro, RO Escárcega, J Rojas-Rodriguez, LE Escobar |
Revue du Rhumatisme | 2007 |
Association of TGF-β1 codon 25 (G915C) polymorphism with hepatitis C virus infection
FA Pereira, NN da Silva, IF Rodart, TM Carmo, DC Lemaire, MG Reis |
Journal of Medical Virology | 2007 |
The interleukin-6 (IL6)–174 G/C promoter genotype is associated with the presence of septic shock and the ex vivo secretion of IL6
JJ Tischendorf, E Yagmur, D Scholten, D Vidacek, A Koch, R Winograd, AM Gressner, C Trautwein, HE Wasmuth, F Lammert |
International Journal of Immunogenetics | 2007 |
Impact of interleukin 6 −174G>C polymorphism on obesity-related metabolic disorders in people with excess in body weight
E Goyenechea, D Parra, JA Martínez |
Metabolism | 2007 |
IL2 and TNFA Gene Polymorphisms and the Risk of Graft-versus-Host Disease after Allogeneic Haematopoietic Stem Cell Transplantation
DO Viel, LT Tsuneto, CR Sossai, SR Lieber, SB Marques, AC Vigorito, FJ Aranha, KA de Eid, GB Oliveira, EC Miranda, CA de Souza, JE Visentainer |
Scandinavian Journal of Immunology | 2007 |
Genetic susceptibility and body mass in childhood cancer survivors
JA Ross |
Pediatric Blood & Cancer | 2007 |
Renal Allograft Immune Response Is Influenced by Patient and Donor Cytokine Genotypes
A Canossi, A Piazza, E Poggi, G Ozzella, MD Rocco, F Papola, G Iaria, D Adorno |
Transplantation Proceedings | 2007 |
Association and interaction of the TNF-alpha gene with other pro- and anti-inflammatory cytokine genes and HLA genes in patients with type 1 diabetes from North India
R Kumar, R Goswami, S Agarwal, N Israni, SK Singh, R Rani |
Tissue Antigens | 2007 |
Screening the human serum proteome for genotype–phenotype associations: An analysis of theIL6 –174G>C polymorphism
CM Hegedus, CF Skibola, P Bracci, EA Holly, MT Smith |
PROTEOMICS | 2007 |
Lack of association between genetic polymorphisms in cytokine genes and disease expression in patients with hereditary non-polyposis colorectal cancer
BA Talseth, C Meldrum, J Suchy, G Kurzawski, J Lubinski, RJ Scott |
Scandinavian Journal of Gastroenterology | 2007 |
Elevated IL‐6 levels in the synovial fluid of osteoarthritis patients stem from plasma cells
F Doß, J Menard, M Hauschild, HJ Kreutzer, T Mittlmeier, M MüllerSteinhardt, B Müller |
Scandinavian Journal of Rheumatology | 2007 |
Interleukin-4 Promoter Polymorphisms: A Genetic Prognostic Factor for Survival in Metastatic Renal Cell Carcinoma
T Kleinrath, C Gassner, P Lackner, M Thurnher, R Ramoner |
Journal of Clinical Oncology | 2007 |
Association of cytokine genetic polymorphism with hepatites B infection evolution in adult patients
CS Ribeiro, JE Visentainer, RA Moliterno |
Memórias do Instituto Oswaldo Cruz | 2007 |
Single-nucleotide polymorphisms in selected cytokine genes and risk of adult glioma
AV Brenner, MA Butler, SS Wang, AM Ruder, N Rothman, PA Schulte, SJ Chanock, HA Fine, MS Linet, PD Inskip |
Carcinogenesis | 2007 |
Gene Polymorphisms and the Prevalence of Key Periodontal Pathogens
L Nibali, DR Ready, M Parkar, PM Brett, M Wilson, MS Tonetti, GS Griffiths |
Journal of dental research | 2007 |
The Interleukin-6 inflammation pathway from cholesterol to aging – Role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases
S Omoigui |
Immunity & Ageing | 2007 |
Effects of the Interaction between Interleukin-6-634C/G Polymorphism and Smoking on Serum C-Reactive Protein Concentrations
Y SAIJO, E YOSHIOKA, T FUKUI, M KAWAHARADA, F SATA, H SATO, R KISHI |
Hypertension Research | 2007 |
Are Promoter Polymorphisms of Interleukin 6 Ready to Be Applied in Genetic Markers of Cardiovascular Diseases?
S IWAMOTO |
Hypertension Research | 2007 |
Cytokines in Human Health
RV House, J Descotes |
2007 | |
Bone Marrow and Stem Cell Transplantation
M Beksac |
2007 | |
Interleukin-6 Genetic Variability and Adiposity: Associations in Two Prospective Cohorts and Systematic Review in 26,944 Individuals
L Qi, C Zhang, RM van Dam, FB Hu |
The Journal of clinical endocrinology and metabolism | 2007 |
Candidate Gene Genotypes, Along with Conventional Risk Factor Assessment, Improve Estimation of Coronary Heart Disease Risk in Healthy UK Men
SE Humphries, JA Cooper, PJ Talmud, GJ Miller |
Clinical chemistry | 2007 |
IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study.
Walston JD, Fallin MD, Cushman M, Lange L, Psaty B, Jenny N, Browner W, Tracy R, Durda P, Reiner A |
Human Genetics | 2007 |
Mature-onset obesity in interleukin-1 receptor I knockout mice
MC García, I Wernstedt, A Berndtsson, M Enge, M Bell, O Hultgren, M Horn, B Ahrén, S Enerback, C Ohlsson, V Wallenius, JO Jansson |
Diabetes | 2006 |
Cytokine gene polymorphisms in retinal detachment patients with and without proliferative vitreoretinopathy: a preliminary study
MR Ruiz-Colmenares, JC Jimeno, JA Adrados, JJ Orriols, MI Fernández |
Acta Ophthalmologica Scandinavica | 2006 |
Lack of association of interleukin-6 and interleukin-8 gene polymorphisms in Chinese patients with systemic lupus erythematosus
CM Huang, AP Huo, CH Tsai, CL Chen, FJ Tsai |
Journal of Clinical Laboratory Analysis | 2006 |
The role of cardiopulmonary fitness and its genetic influences on surgical outcomes
JT Lee, EJ Chaloner, SJ Hollingsworth |
British Journal of Surgery | 2006 |
Concordance of functional in vitro data and epidemiological associations in complex disease genetics
JP Ioannidis, FK Kavvoura |
Genetics in Medicine | 2006 |
Case?control study in basal cell carcinoma of the skin: single nucleotide polymorphisms in three interleukin promoters pre-analysed in pooled DNA
S Wilkening, K Hemminki, P Rudnai, E Gurzau, K Koppova, R Kumar, A Försti |
British Journal of Dermatology | 2006 |
Polymorphisms of interleukin-6, hepatic lipase and calpain-10 genes, and preeclampsia
T Saarela, M Hiltunen, S Helisalmi, S Heinonen, M Laakso |
European Journal of Obstetrics & Gynecology and Reproductive Biology | 2006 |
Influence of the −308 TNF-α and −174 IL-6 polymorphisms on lipid profile in Mexican subjects
I Parra-Rojas, B Ruíz-Madrigal, E Martínez-López, A Panduro |
Hereditas | 2006 |
Genetic and environmental contributions to plasma C-reactive protein and interleukin-6 levels – a study in twins
MA Wörns, A Victor, PR Galle, T Höhler |
Genes and Immunity | 2006 |
Variants Associated with Common Disease Are Not Unusually Differentiated in Frequency across Populations
KE Lohmueller, MM Mauney, D Reich, JM Braverman |
The American Journal of Human Genetics | 2006 |
Blood and synovial fluid cytokine signatures in patients with juvenile idiopathic arthritis: a cross-sectional study
W Jager, EP Hoppenreijs, NM Wulffraat, LR Wedderburn, W Kuis, BJ Prakken |
Annals of the rheumatic diseases | 2006 |
Novel IL10 gene family associations with systemic juvenile idiopathic arthritis
MS Fife, A Gutierrez, EM Ogilvie, CJ Stock, JM Samuel, W Thomson, LF Mack, CM Lewis, P Woo |
Arthritis Research & Therapy | 2006 |
Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review
SP Balasubramanian, IA Azmy, SE Higham, AG Wilson, SS Cross, A Cox, NJ Brown, MW Reed |
BMC Cancer | 2006 |
The interleukin-6 gene -174G>C and -572G>C promoter polymorphisms are related to cerebral aneurysms
L Morgan, J Cooper, H Montgomery, N Kitchen, SE Humphries |
Journal of neurology, neurosurgery, and psychiatry | 2006 |
IL-10, IL-6 and CD14 polymorphisms and sepsis outcome in ventilated very low birth weight infants
RJ Baier, J Loggins, K Yanamandra |
BMC Medicine | 2006 |
Analysis of G(-174)C IL-6 polymorphism and plasma concentrations of inflammatory markers in patients with type 2 diabetes and peripheral arterial disease
M Libra, SS Signorelli, Y Bevelacqua, PM Navolanic, V Bevelacqua, J Polesel, R Talamini, F Stivala, MC Mazzarino, G Malaponte |
Journal of clinical pathology | 2006 |
Innate immunity SNPs are associated with risk for severe sepsis after burn injury
RC Barber, LY Chang, BD Arnoldo, GF Purdue, JL Hunt, JW Horton, CC Aragaki |
Clinical medicine & research | 2006 |
Polycystic Ovarian Syndrome
KA Khan, S Stas, LR Kurukulasuriya |
Journal of the CardioMetabolic Syndrome | 2006 |
The IL - 6 promoter polymorphism is associated with disease activity and disability in systemic sclerosis
RS Cornateanu, C Mihai, S Balan, R Ionescu, E Moldoveanu |
Journal of Cellular and Molecular Medicine | 2006 |
Interleukin 6: from bench to bedside
N Nishimoto, T Kishimoto |
Nature Clinical Practice Rheumatology | 2006 |
Risk of adverse post-transplant events after kidney allograft transplantation as predicted by CTLA-4 +49 and TNF-α −308 single nucleotide polymorphisms: A preliminary study
K Gendzekhadze, P Rivas-Vetencourt, RF Montano |
Transplant Immunology | 2006 |
Interleukin-6–174 G>C polymorphism affects the association between IL-6 plasma levels and insulin resistance in type 2 diabetic patients
R Testa, F Olivieri, AR Bonfigli, C Sirolla, M Boemi, F Marchegiani, M Marra, S Cenerelli, R Antonicelli, A Dolci, G Paolisso, C Franceschi |
Diabetes Research and Clinical Practice | 2006 |
Polymorphism of interferon–gamma gene at position +874 and clinical characteristics of chronic hepatitis C
CY Dai, WL Chuang, MY Hsieh, LP Lee, NJ Hou, SC Chen, ZY Lin, MY Hsieh, LY Wang, JF Tsai, WY Chang, ML Yu |
Translational Research | 2006 |
Pharmacogenetics: Progress, pitfalls and clinical potential for coronary heart disease
SE Humphries, A Hingorani |
Vascular Pharmacology | 2006 |
Common Polymorphism in Interleukin 6 Influences Survival of Women with Ovarian and Peritoneal Carcinoma
R Garg, M Wollan, V Galic, R Garcia, BA Goff, HJ Gray, E Swisher |
Gynecologic Oncology | 2006 |
Polymorphisms in the interleukin 6 and transforming growth factor β1 gene and risk of dementia
M Oijen, PP Arp, FJ de Jong, A Hofman, PJ Koudstaal, AG Uitterlinden, MM Breteler |
Neuroscience Letters | 2006 |
Genetic Predisposition and Renal Allograft Failure: Implication of Non-HLA Genetic Variants
F Khan, S Agrawal, S Agrawal |
Molecular diagnosis & therapy | 2006 |
Disparate Distribution of 16 Candidate Single Nucleotide Polymorphisms Among Racial and Ethnic Groups of Pediatric Heart Transplant Patients:
DM Girnita, SA Webber, R Ferrell, GJ Burckart, MM Brooks, KK McDade, R Chinnock, C Canter, L Addonizio, D Bernstein, JK Kirklin, AL Girnita, A Zeevi |
Transplantation | 2006 |
The Autoimmune Diseases
I Kang, J Craft |
The Autoimmune Diseases | 2006 |
The Human Calcium-Sensing Receptor and Interleukin-6 Genes are Associated with Bone Mineral Density in Chinese
YB WANG, JJ GUO, YJ LIU, FY DENG, DK JIANG, HW DENG |
Acta Genetica Sinica | 2006 |
Interleukin-6 gene polymorphism -174G/C influences plasma lipid levels in women
S Henningsson, A Håkansson, L Westberg, F Baghaei, R Rosmond, G Holm, A Ekman, H Nissbrandt, E Eriksson |
Obesity | 2006 |
Impaired regulation of immune responses in cognitive decline and Alzheimer’s disease: lessons from genetic association studies
M Chiappelli, E Tumini, E Porcellini, F Licastro |
Expert Review of Neurotherapeutics | 2006 |
Interleukin-6 involvement in brain arteriovenous malformations
Y Chen, L Pawlikowska, JS Yao, F Shen, W Zhai, AS Achrol, MT Lawton, PY Kwok, GY Yang, WL Young |
Annals of Neurology | 2006 |
Interleukin (IL)–12, IL-2, and IL-6 Gene Polymorphisms in Takayasu’s Arteritis from Turkey
G Saruhan-Direskeneli, M Bıçakçıgil, V Yılmaz, S Kamalı, K Aksu, I Fresko, N Akkoç, S Kiraz, HT Özer, E Tunç, E Yücel, Y Karaarslan, FA Uyar, E Doganavşargil, M Inanc, H Direskeneli |
Human Immunology | 2006 |
IL6 Gene Promoter Polymorphisms and Type 2 Diabetes: Joint Analysis of Individual Participants' Data From 21 Studies
C Huth, IM Heid, C Vollmert, C Gieger, H Grallert, JK Wolford, B Langer, B Thorand, N Klopp, YH Hamid, O Pedersen, T Hansen, V Lyssenko, L Groop, C Meisinger, A Doring, H Lowel, W Lieb, C Hengstenberg, W Rathmann, S Martin, JW Stephens, H Ireland, H Mather, GJ Miller, HM Stringham, M Boehnke, J Tuomilehto, H Boeing, M Mohlig, J Spranger, A Pfeiffer, I Wernstedt, A Niklason, A Lopez-Bermejo, JM Fernandez-Real, RL Hanson, L Gallart, J Vendrell, A Tsiavou, E Hatziagelaki, SE Humphries, HE Wichmann, C Herder, T Illig |
Diabetes | 2006 |
Susceptibility to JRA/JIA: complementing general autoimmune and arthritis traits
JD Phelan, SD Thompson, DN Glass |
Genes and Immunity | 2006 |
Dissociation of inflammatory markers and natural killer cell activity in major depressive disorder
JL Pike, MR Irwin |
Brain, Behavior, and Immunity | 2006 |
Cytokine Gene Polymorphisms Are Not Associated With Bronchiolitis Obliterans Syndrome or Survival After Lung Transplant
LD Snyder, MG Hartwig, T Ganous, RD Davis, WF Herczyk, NL Reinsmoen, DA Schwartz, SM Palmer |
The Journal of Heart and Lung Transplantation | 2006 |
The −174G/C interleukin-6 promoter polymorphism influences the development of macular oedema following uncomplicated phacoemulsification surgery
I Masood, A Negi, SA Vernon, P Comeglio, AH Child |
Eye | 2006 |
Weight regain after slimming induced by an energy-restricted diet depends on interleukin-6 and peroxisome-proliferator-activated-receptor-γ2 gene polymorphisms
E Goyenechea, MD Parra, JA Martínez |
British Journal of Nutrition | 2006 |
Increase in interleukin-6 following arterial injury is related to insulin resistance, the ?174G?C polymorphism and complex plaque morphology
SP Marso, JA House, PJ Hopkins |
International Journal of Immunogenetics | 2006 |
Hostility and pain are related to inflammation in older adults
JE Graham, TF Robles, JK Kiecolt-Glaser, WB Malarkey, MG Bissell, R Glaser |
Brain, Behavior, and Immunity | 2006 |
Interleukin-6 −174 G/C promoter polymorphism and effects of fenofibrate and simvastatin on inflammatory markers in hypercholesterolemic patients:
DP Potaczek, A Undas, M Celinska-Lowenhoff, A Szczeklik |
Blood Coagulation & Fibrinolysis | 2006 |
Association of Sudden Infant Death Syndrome With VEGF and IL-6 Gene Polymorphisms
M Dashash, V Pravica, IV Hutchinson, AJ Barson, DB Drucker |
Human Immunology | 2006 |
The association of cytokine gene polymorphisms with febrile non-hemolytic transfusion reaction in multitransfused patients
M Addas-Carvalho, TS Salles, ST Saad |
Transfusion Medicine | 2006 |
Proinflammatory cytokine gene polymorphisms among Hashimoto's thyroiditis patients
RH Chen, CT Chang, WC Chen, CH Tsai, FJ Tsai |
Journal of Clinical Laboratory Analysis | 2006 |
Recovery of CD4+ T Cells in HIV Patients With a Stable Virologic Response to Antiretroviral Therapy Is Associated With Polymorphisms of Interleukin-6 and Central Major Histocompatibility Complex Genes:
S Fernandez, AA Rosenow, IR James, SG Roberts, RC Nolan, MA French, P Price |
Journal of acquired immune deficiency syndromes (1999) | 2006 |
Cytokine gene polymorphisms can alter the effect of Bacillus Calmette–Guérin (BCG) immunotherapy
B Basturk, I Yavascaoglu, B Oral, G Göral, B Oktay |
Cytokine | 2006 |
Interleukin-6 response to isokinetic exercise in elite athletes: relationships to adrenocortical function and to mechanical and myoelectric fatigue
MA Minetto, A Rainoldi, M Gazzoni, GP Ganzit, L Saba, P Paccotti |
European Journal of Applied Physiology | 2006 |
IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4
H Grallert, C Huth, M Kolz, C Meisinger, C Herder, K Strassburger, G Giani, HE Wichmann, J Adamski, T Illig, W Rathmann |
Experimental Gerontology | 2006 |
Genetic Analysis of Juvenile Rheumatoid Arthritis: Approaches to Complex Traits
S Prahalad |
Current Problems in Pediatric and Adolescent Health Care | 2006 |
IL6 G-174C Associated With Sudden Infant Death Syndrome in a Caucasian Australian Cohort
SM Moscovis, AE Gordon, OM Madani, M Gleeson, RJ Scott, J Roberts-Thomson, ST Hall, DM Weir, A Busuttil, CC Blackwell |
Human Immunology | 2006 |
No Association Between Selected Candidate Gene Polymorphisms and Severe Chronic Periodontitis
JC Wohlfahrt, T Wu, JS Hodges, JE Hinrichs, BS Michalowicz |
Journal of Periodontology | 2006 |
Role of Single Nucleotide Polymorphisms of Cytokine Genes in Spontaneous Preterm Delivery
EM Speer, DA Gentile, A Zeevi, G Pillage, D Huo, DP Skoner |
Human Immunology | 2006 |
Interleukin-6 g.−174G>C Promoter Polymorphism Is Associated with Obesity in the EPIC-Potsdam Study*
K Klipstein-Grobusch, M Möhlig, J Spranger, K Hoffmann, FU Rodrigues, AM Sharma, S Klaus, AF Pfeiffer, H Boeing |
Obesity | 2006 |
Systemic juvenile idiopathic arthritis: diagnosis, management, and outcome
P Woo |
Nature clinical practice. Rheumatology | 2006 |
Common Genetic Vulnerability to Depressive Symptoms and Coronary Artery Disease: A Review and Development of Candidate Genes Related to Inflammation and Serotonin:
JM McCaffery, N Frasure-Smith, MP Dubé, P Théroux, GA Rouleau, QL Duan, F Lespérance |
Psychosomatic medicine | 2006 |
Interleukin-6 polymorphisms and the risk of cervical cancer
NN de Souza, S Brenna, F Campos, K Syrjanen, E Baracat, I Silva |
International Journal of Gynecological Cancer | 2006 |
Th1 and Th2 cytokine gene polymorphisms in two indigenous ethnic groups in Iran
A Amirzargar, M Sadeghi, F Khosravi, S Dianat, M Naroueynejad, MH Nicknam, N Hatmi, B Ansaripour, B Moradi, B Nikbin |
International Journal of Immunogenetics | 2006 |
Fibrinogen and CRP in Israeli families: Genetic and environmental sources of concentrations and longitudinal changes
Y Friedlander, JD Kark, R Sinnreich, RP Tracy, DS Siscovick |
Atherosclerosis | 2006 |
Relation between common polymorphisms in genes related to inflammatory response and colorectal cancer
G Theodoropoulos, I Papaconstantinou, E Felekouras, N Nikiteas, P Karakitsos, D Panoussopoulos, AC Lazaris, E Patsouris, J Bramis, M Gazouli |
World journal of gastroenterology : WJG | 2006 |
Systemic Inflammation in COPD: Is Genetic Susceptibility a Key Factor?
DG Yanbaeva, MA Dentener, EC Creutzberg, EF Wouters |
COPD | 2006 |
Cytokine Gene Polymorphisms in Multifactorial Conditions
T Laitinen |
Cytokine Gene Polymorphisms in Multifactorial Conditions | 2006 |
The Genetic Determinants of Renal Impairment Following Cardiac Surgery
RB Yates, M Stafford-Smith |
Seminars in cardiothoracic and vascular anesthesia | 2006 |
Genetic variation in IL6 gene and type 2 diabetes: tagging-SNP haplotype analysis in large-scale case–control study and meta-analysis
L Qi, RM van Dam, JB Meigs, JA Manson, D Hunter, FB Hu |
Human Molecular Genetics | 2006 |
Reduced stress- and cold-induced increase in energy expenditure in interleukin-6-deficient mice
I Wernstedt, A Edgley, A Berndtsson, J Fäldt, G Bergström, V Wallenius, JO Jansson |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2006 |
CD16 + monocytes produce IL-6, CCL2, and matrix metalloproteinase-9 upon interaction with CX3CL1-expressing endothelial cells
P Ancuta, J Wang, D Gabuzda |
Journal of leukocyte biology | 2006 |
Principles of Molecular Medicine
MS Runge, C Patterson |
2006 | |
Genetic polymorphisms of inflammatory cytokines and myocardial infarction in the elderly
F Olivieri, R Antonicelli, M Cardelli, F Marchegiani, L Cavallone, E Mocchegiani, C Franceschi |
Mechanisms of Ageing and Development | 2006 |
Associations between Interleukin-6 Genetic Polymorphisms and Levels of Autoantibodies to 60-kDa Heat-Shock Proteins
P Kiszel, G Füst, T Pessi, M Hurme, Z Prohászka |
Human Heredity | 2006 |
Interleukin-6 response to isokinetic exercise in elite athletes: relationships to adrenocortical function and to mechanical and myoelectric fatigue.
Minetto MA, Rainoldi A, Gazzoni M, Ganzit GP, Saba L, Paccotti P |
European Journal of Applied Physiology | 2006 |
Proinflammatory cytokine gene polymorphisms among Hashimoto's thyroiditis patients.
Chen RH, Chang CT, Chen WC, Tsai CH, Tsai FJ |
Journal of Clinical Laboratory Analysis | 2006 |
Influence of IL-6, COL1A1, and VDR gene polymorphisms on bone mineral density in Crohn's disease
CE Todhunter, A Sutherland-Craggs, SA Bartram, PT Donaldson, AK Daly, RM Francis, JC Mansfield, NP Thompson |
Gut | 2005 |
The use of anakinra in juvenile arthritis
A Reiff |
Current Rheumatology Reports | 2005 |
Genetic variation associated with preterm birth: A HuGE review
KS Crider, N Whitehead, RM Buus |
Genetics in Medicine | 2005 |
The interleukin-6 −174 single nucleotide polymorphism: Cervical protein production and the risk of preterm delivery
WE Jamie, RK Edwards, RJ Ferguson, P Duff |
American Journal of Obstetrics and Gynecology | 2005 |
Genetic determinants of blood pressure regulation
JB Marteau, M Zaiou, G Siest, S Visvikis-Siest |
Journal of Hypertension | 2005 |
Interaction of polymorphisms in the genes encoding interleukin-6 and estrogen receptor beta on the susceptibility to Parkinson's disease
A H�kansson, L Westberg, S Nilsson, S Buervenich, A Carmine, B Holmberg, O Sydow, L Olson, B Johnels, E Eriksson, H Nissbrandt |
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics | 2005 |
TNF-α-, TNF-β-, IL-6-, and IL-10-promoter polymorphisms in patients with chronic obstructive pulmonary disease
C Seifart, A Dempfle, A Plagens, U Seifart, U Clostermann, B Müller, C Vogelmeier, P Wichert |
Tissue Antigens | 2005 |
Gene variants for osteoporosis and their pleiotropic effects in aging
SL Ferrari, R Rizzoli |
Molecular Aspects of Medicine | 2005 |
Open label phase II trial of single, ascending doses of MRA in Caucasian children with severe systemic juvenile idiopathic arthritis: proof of principle of the efficacy of IL-6 receptor blockade in this type of arthritis and demonstration of prolonged clinical improvement
P Woo, N Wilkinson, AM Prieur, T Southwood, V Leone, P Livermore, H Wythe, D Thomson, T Kishimoto |
Arthritis Research & Therapy | 2005 |
Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the -174 IL-6 G/C polymorphism in children
A Sawczenko, O Azooz, J Paraszczuk, M Idestrom, NM Croft, MO Savage, AB Ballinger, IR Sanderson |
Proceedings of the National Academy of Sciences | 2005 |
Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study
H Bukulmez, M Fife, M Tsoras, SD Thompson, NA Twine, P Woo, JM Olson, RC Elston, DN Glass, RA Colbert |
Arthritis Research & Therapy | 2005 |
Pro- and anti-inflammatory cytokine gene polymorphism profiles in Bulgarian multiple sclerosis patients
S Mihailova, M Ivanova, A Mihaylova, L Quin, O Mikova, E Naumova |
Journal of Neuroimmunology | 2005 |
Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association
A Nieters, JM Yuan, CL Sun, ZQ Zhang, J Stoehlmacher, S Govindarajan, MC Yu |
Cancer | 2005 |
Associations of the −174 G/C Interleukin-6 Gene Promoter Polymorphism with Serum Interleukin 6 and Mortality in the Elderly
G Ravaglia, P Forti, F Maioli, M Chiappelli, P Dolzani, M Martelli, M Bianchin, E Mariani, L Bolondi, F Licastro |
Biogerontology | 2005 |
The interleukin-6 −174 promoter polymorphism is associated with extrapulmonary bacterial dissemination in Streptococcus pneumoniae infection
B Schaaf, J Rupp, M Müller-Steinhardt, J Kruse, F Boehmke, M Maass, P Zabel, K Dalhoff |
Cytokine | 2005 |
Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia
T Lehrnbecher, T Bernig, M Hanisch, U Koehl, M Behl, D Reinhardt, U Creutzig, T Klingebiel, SJ Chanock, D Schwabe |
Leukemia | 2005 |
Polymorphism of host response genes: Implications in the pathogenesis and treatment of acute renal failure
BL Jaber, BJ Pereira, JV Bonventre, VS Balakrishnan |
Kidney International | 2005 |
Role of interaction between variants in the PPARG and interleukin-6 genes on obesity related metabolic risk factors
M Barbieri, MR Rizzo, M Papa, R Acampora, LD Angelis, F Olivieri, F Marchegiani, C Franceschi, G Paolisso |
Experimental Gerontology | 2005 |
TNF-α −308G/A and IL-6 −174 G/C polymorphisms in the Turkish pediatric stroke patients
ZC Karahan, G Deda, T Sipahi, AH Elhan, N Akar |
Thrombosis Research | 2005 |
Interleukin-6 gene polymorphism and risk of osteoarthritis of the hip: a case–control study
E Pola, P Papaleo, R Pola, E Gaetani, F Tamburelli, L Aulisa, C Logroscino |
Osteoarthritis and Cartilage | 2005 |
NeuroImmune Biology
R Solana, G Pawelec |
NeuroImmune Biology | 2005 |
Genetic polymorphisms in sepsis:
MK Dahmer, A Randolph, S Vitali, MW Quasney |
Pediatric Critical Care Medicine | 2005 |
Targeting the interleukin-6 receptor: A new treatment for systemic juvenile idiopathic arthritis?
F Benedetti, A Martini |
Arthritis & Rheumatism | 2005 |
Artritis juveniles idiopáticas
P Quartier, AM Prieur |
EMC - Tratado de Medicina | 2005 |
Differentiation-dependent expression and mitogenic action of interleukin-6 in human colon carcinoma cells: Relevance for tumour progression
W Brozek, G Bises, T Girsch, HS Cross, HE Kaiser, M Peterlik |
European Journal of Cancer | 2005 |
Measuring Immunity
MT Stang, JH Yim |
Measuring Immunity | 2005 |
The biology, utilization, and attenuation of C-reactive protein in cardiovascular disease: Part I
A Armani, RC Becker |
American Heart Journal | 2005 |
Cytokine gene polymorphisms in Japanese patients with hepatitis B virus infection—association between TGF-β1 polymorphisms and hepatocellular carcinoma
K Migita, S Miyazoe, Y Maeda, M Daikoku, S Abiru, T Ueki, K Yano, S Nagaoka, T Matsumoto, K Nakao, K Hamasaki, H Yatsuhashi, H Ishibashi, K Eguchi |
Journal of Hepatology | 2005 |
The pharmacogenetic impact of inflammatory genes on bladder cancer recurrence
J Gu, HB Grossman, CP Dinney, X Wu |
Pharmacogenomics | 2005 |
Genetic polymorphisms and sepsis
J Arcaroli, MB Fessler, E Abraham |
Shock | 2005 |
Juvenile Idiopathic Arthritis
JE Weiss, NT Ilowite |
Pediatric Clinics of North America | 2005 |
IL-6 and IL-10 promoter gene polymorphisms do not associate with the susceptibility for multiple myeloma
G Mazur, K Bogunia-Kubik, T Wróbel, L Karabon, M Polak, K Kuliczkowski, A Lange |
Immunology Letters | 2005 |
Effect of the Interleukin-6 (−174) G/C Promoter Polymorphism on Adiponectin and Insulin Sensitivity
X Yang, PA Jansson, F Pellmé, M Laakso, U Smith |
Obesity research | 2005 |
Cytokine gene polymorphisms as potential risk and protective factors in renal cell carcinoma
B Baştürk, İ Yavaşçaoğlu, H Vuruşkan, G Göral, B Oktay, HB Oral |
Cytokine | 2005 |
Genetic variations in IL6 associate with intervertebral disc disease characterized by sciatica
N Noponen-Hietala, I Virtanen, R Karttunen, S Schwenke, E Jakkula, H Li, R Merikivi, S Barral, J Ott, J Karppinen, L Ala-Kokko |
PAIN | 2005 |
Interleukin-6 (IL-6) − 373 A9T11 allele is associated with reduced susceptibility to chronic periodontitis in Japanese subjects and decreased serum IL-6 level
Y Komatsu, H Tai, JC Galicia, Y Shimada, M Endo, K Akazawa, K Yamazaki, H Yoshie |
Tissue Antigens | 2005 |
IL-6 and IL-10 Promoter Gene Polymorphisms of Patients and Donors of Allogeneic Sibling Hematopoietic Stem Cell Transplants Associate With the Risk of Acute Graft-Versus-Host Disease
L Karabon, B Wysoczanska, K Bogunia-Kubik, K Suchnicki, A Lange |
Human Immunology | 2005 |
Detection of a single nucleotide polymorphism in the IL-6 promoter region of ancient nuclear DNA
LA Larcombe, P Nickerson, RD Hoppa, C Matheson |
Infection, Genetics and Evolution | 2005 |
The genetics of stroke:
L Morgan, SE Humphries |
Current Opinion in Lipidology | 2005 |
Interleukin-6 Genetic Polymorphism and Chinese Major Depression
CJ Hong, YW Yu, TJ Chen, SJ Tsai |
Neuropsychobiology | 2005 |
Genetic and clinical factors influence the baseline permeability of the peritoneal membrane
G Gillerot, E Goffin, C Michel, P Evenepoel, WV Biesen, M Tintillier, P Stenvinkel, O Heimburger, B Lindholm, L Nordfors, A Robert, O Devuyst |
Kidney International | 2005 |
Interleukin-6 Polymorphism: A Genetic Risk Factor for Cardiac Transplant Related Coronary Vasculopathy?
CG Densem, M Ray, IV Hutchinson, N Yonan, NH Brooks |
The Journal of Heart and Lung Transplantation | 2005 |
A comparison of methods for determining genotypes at the tumour necrosis factor-alpha -308, interleukin (IL)-1beta +3953, IL-6 -174 and IL-10 -1082/-819/-592 polymorphic loci
MJ Bown, S Weston, T Horsburgh, ML Nicholson, PR Bell, RD Sayers |
International Journal of Immunogenetics | 2005 |
Interleukin-6-174-genotype, sepsis and cerebral injury in very low birth weight infants
W Göpel, C Härtel, P Ahrens, I König, E Kattner, E Kuhls, H Küster, J Möller, D Müller, B Roth, H Segerer, C Wieg, E Herting |
Genes and Immunity | 2005 |
Physical Function and Its Response to Exercise: Associations With Cytokine Gene Variation in Older Adults With Knee Osteoarthritis
BJ Nicklas, J Mychaleckyj, S Kritchevsky, S Palla, LA Lange, EM Lange, SP Messier, D Bowden, M Pahor |
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences | 2005 |
Frequencies of the common promoter polymorphisms in cytokine genes in a Polish population
M Kurzawski, A Pawlik, B Czerny, L Domanski, J Rozanski, M Drozdzik |
International Journal of Immunogenetics | 2005 |
Relationship between cytokine gene polymorphisms and graft-versus-host disease after allogeneic stem cell transplantation in a Brazilian population
JE Visentainer, SR Lieber, LB Persoli, SB Marques, AC Vigorito, FJ Aranha, KA de Eid, GB Oliveira, EC Miranda, L Bragotto, CA de Souza |
Cytokine | 2005 |
Non-HLA immunogenetics in hematopoietic stem cell transplantation
AM Dickinson, D Charron |
Current Opinion in Immunology | 2005 |
Polymorphisms in the interferon-γ gene at position +874 in patients with chronic hepatitis C treated with high-dose interferon-α and ribavirin
CY Dai, WL Chuang, WY Chang, SC Chen, LP Lee, MY Hsieh, NJ Hou, ZY Lin, MY Hsieh, LY Wang, ML Yu |
Antiviral Research | 2005 |
Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: The cardiovascular health study
AP Reiner, P Diehr, WS Browner, SE Humphries, NS Jenny, M Cushman, RP Tracy, J Walston, T Lumley, AB Newman, LH Kuller, BM Psaty |
Atherosclerosis | 2005 |
Cytokine Gene Polymorphisms and Genetic Association with Coeliac Disease in the Finnish Population
N Woolley, K Mustalahti, M Maki, J Partanen |
Scandinavian Journal of Immunology | 2005 |
IL6, IL10 and TGFB1 gene polymorphisms in coeliac disease: differences between DQ2 positive and negative patients
JA Garrote, E Arranz, E Gómez-González, AJ León, C Farré, C Calvo, D Bernardo, L Fernández-Salazar, A Blanco-Quirós |
Allergologia et Immunopathologia | 2005 |
Association tests of interleukin-6 (IL-6) and type II tumor necrosis factor receptor (TNFR2) genes with bone mineral density in Caucasians using a re-sampling approach
P Xiao, PY Liu, Y Lu, YF Guo, DH Xiong, LH Li, RR Recker, HW Deng |
Human Genetics | 2005 |
Effect of genetic variability on the inflammatory response to periodontal infection
L Shapira, A Wilensky, DF Kinane |
Journal of Clinical Periodontology | 2005 |
C-reactive protein (+1444C>T) polymorphism influences CRP response following a moderate inflammatory stimulus
F D’Aiuto, JP Casas, T Shah, SE Humphries, AD Hingorani, MS Tonetti |
Atherosclerosis | 2005 |
A Case-Control Study in IL6 and TGFB1 Gene Polymorphisms and Recurrent Spontaneous Abortion in Southern Brazilian Patients
R Linsingen, EP Bompeixe, MG Bicalho |
American Journal of Reproductive Immunology | 2005 |
Lack of association between pro-inflammatory cytokine (IL-6, IL-8 and TNF-alpha) gene polymorphisms and Graves' disease
RH Chen, WC Chen, TY Wang, CH Tsai, FJ Tsai |
International Journal of Immunogenetics | 2005 |
Polymorphisms of interleukin-1 gene complex, IL6 and tumour necrosis factor genes in chronic idiopathic neutropenia of adults
M Addas-Carvalho, EV Paula, CS Lima, ST Saad |
Annals of Hematology | 2005 |
Increased Cytokine Secretion in Patients with Failed Implants Compared with Patients with Primary Implants:
J Waddell, KP Pritzker, EL Boynton |
Clinical Orthopaedics and Related Research® | 2005 |
Association ofSLC11A1 (NRAMP1) with persistent oligoarticular and polyarticular rheumatoid factor-negative juvenile idiopathic arthritis in Finnish patients: Haplotype analysis in Finnish families
JA Runstadler, H S�il�, A Savolainen, M Leirisalo-Repo, K Aho, E Tuomilehto-Wolf, J Tuomilehto, MF Seldin |
Arthritis & Rheumatism | 2005 |
The interleukin-6 −174 G>C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients
R Antonicelli, F Olivieri, M Bonafè, L Cavallone, L Spazzafumo, F Marchegiani, M Cardelli, A Recanatini, P Testarmata, M Boemi, G Parati, C Franceschi |
International Journal of Cardiology | 2005 |
Clearance of hepatitis C virus is not associated with single nucleotide polymorphisms in the IL-1, -6, or -10 genes
EJ Minton, D Smillie, P Smith, S Shipley, MW McKendrick, DC Gleeson, JC Underwood, C Cannings, AG Wilson |
Human Immunology | 2005 |
The influence of gender on human innate immunity
SD Imahara, S Jelacic, CE Junker, GE O'Keefe |
Surgery | 2005 |
Effect of IL-6 promoter polymorphism on incidence and outcome in Hodgkin's lymphoma
P Cordano, A Lake, L Shield, GM Taylor, FE Alexander, PR Taylor, J White, RF Jarrett |
British Journal of Haematology | 2005 |
The –174G/C Polymorphism of the Interleukin 6 Gene Is a Hallmark of Lacunar Stroke and Not Other Ischemic Stroke Phenotypes
A Chamorro, M Revilla, V Obach, M Vargas, AM Planas |
Cerebrovascular Diseases | 2005 |
Mechanisms of nitric oxide-mediated intestinal barrier failure in necrotizing enterocolitis
JS Upperman, D Potoka, A Grishin, D Hackam, R Zamora, HR Ford |
Seminars in Pediatric Surgery | 2005 |
Interleukin-6 gene polymorphism in renal transplant patients with and without gingival overgrowth
M Drozdzik, M Kurzawski, A Drozdzik, K Kotrych, J Banach, A Pawlik |
Journal of Clinical Periodontology | 2005 |
Cytokine-Related Genotypic Differences in Peak Interleukin-6 Blood Levels of Patients with SIRS and Septic Complications:
E Watanabe, H Hirasawa, S Oda, H Shiga, K Matsuda, M Nakamura, R Abe, T Nakada |
The Journal of trauma | 2005 |
Nonassociation of Interleukin 4 intron 3 and 590 Promoter Polymorphisms with Bronchopulmonary Dysplasia for Ventilated Preterm Infants
HC Lin, BH Su, JS Chang, CM Hsu, CH Tsai, FJ Tsai |
Biology of the Neonate | 2005 |
Extremely high interleukin-6 blood levels and outcome in the critically ill are associated with tumor necrosis factor??? and interleukin-1???related gene polymorphisms*:
E Watanabe, H Hirasawa, S Oda, K Matsuda, M Hatano, T Tokuhisa |
Critical Care Medicine | 2005 |
Novel IL-6 haplotypes and disease association
MS Fife, EM Ogilvie, D Kelberman, J Samuel, A Gutierrez, SE Humphries, P Woo |
Genes and Immunity | 2005 |
Impact of genes related to immune tolerance and inflammation (tumour necrosis factor-α, interleukin-6) on blood pressure, protein excretion and oedema in pregnancy:
T Pfab, YP Chen, T Slowinski, CM Richter, M Godes, PC Arck, H Halle, B Hocher |
Journal of Hypertension | 2005 |
The Role of Cytokine Gene Polymorphisms in Determining Disease Susceptibility and Phenotype in Inflammatory Bowel Disease
MJ Cantor, P Nickerson, CN Bernstein |
The American Journal of Gastroenterology | 2005 |
Genetic association of cytokines polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in the Chinese
Lie-Ying Fan, Xiao-Qing Tu, Ye Zhu, Thomas Pfeiffer, Ralph Feltens, Winfried Stoecker, Ren-Qian Zhong |
World journal of gastroenterology : WJG | 2005 |
C-174G Polymorphism in the Promoter of the Interleukin-6 Gene Is Associated With Insulin Resistance
M Cardellini, L Perego, M D'Adamo, MA Marini, C Procopio, ML Hribal, F Andreozzi, S Frontoni, M Giacomelli, M Paganelli, AE Pontiroli, R Lauro, F Folli, G Sesti |
Diabetes care | 2005 |
Is puberty an accelerator of type 1 diabetes in IL6-174CC females?
Kathleen M Gillespie, Runa Nolsøe, Virginie M Betin, Ole P Kristiansen, Polly J Bingley, Thomas Mandrup-Poulsen, Edwin A M Gale |
Diabetes | 2005 |
Interleukin-6 and diabetes: the good, the bad, or the indifferent?
Ole P Kristiansen, Thomas Mandrup-Poulsen |
Diabetes | 2005 |
INTERLEUKIN-6 PROMOTER POLYMORPHISM AND LATE-ONSET ALZHEIMER's DISEASE IN THE FINNISH POPULATION
AM Koivisto, S Helisalmi, J Pihlajamäki, L Moilanen, J Kuusisto, M Laakso, M Hiltunen, K Keijo, T Hänninen, EL Helkala, K Kervinen, YA kesäniemi, H Soininen |
Journal of Neurogenetics | 2005 |
Polymorphisms in Inflammation Genes and Bladder Cancer: From Initiation to Recurrence, Progression, and Survival
D Leibovici, HB Grossman, CP Dinney, RE Millikan, S Lerner, Y Wang, J Gu, Q Dong, X Wu |
Journal of Clinical Oncology | 2005 |
Inflammatory markers and IL-6 polymorphism in peripheral arterial disease with and without diabetes mellitus
P Danielsson, L Truedsson, KF Eriksson, L Norgren |
Vascular medicine (London, England) | 2005 |
The immuno-inflammatory response to trauma
CC Tzioupis, S Katsoulis, N Manidakis, PV Giannoudis |
Trauma | 2005 |
The Interleukin-6 –174G/C Promoter Polymorphism Is Not Associated With Endometriosis in South Indian Women
M Bhanoori, KA Babu, M Deenadayal, S Kennedy, S Shivaji |
Journal of the Society for Gynecologic Investigation | 2005 |
Cytokine genotypes correlate with pain and radiologically defined joint damage in patients with juvenile rheumatoid arthritis
K Oen, PN Malleson, DA Cabral, AM Rosenberg, RE Petty, P Nickerson, M Reed |
Rheumatology (Oxford, England) | 2005 |
Does systemic-onset juvenile idiopathic arthritis belong under juvenile idiopathic arthritis?
AV Ramanan, AA Grom |
Rheumatology (Oxford, England) | 2005 |
Physical activity and modulation of systemic low-level inflammation
H Bruunsgaard |
Journal of leukocyte biology | 2005 |
Interleukin-6 −174G/C polymorphism and longevity: a follow-up study
M Hurme, T Lehtimäki, M Jylhä, PJ Karhunen, A Hervonen |
Mechanisms of Ageing and Development | 2005 |
Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes
YH Hamid, CS Rose, SA Urhammer, C Glmer, R Nolse, OP Kristiansen, T Mandrup-Poulsen, K Borch-Johnsen, T Jorgensen, T Hansen, O Pedersen |
Diabetologia | 2005 |
Cytokine Gene Polymorphisms in Patch‐stage Mycosis Fungoides
E Hodak, L Akerman, M David, T Klein, A Tambur, B Kfir, L Maron, J Sulkes |
Acta Dermato Venereologica | 2005 |
Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians
C Franceschi, F Olivieri, F Marchegiani, M Cardelli, L Cavallone, M Capri, S Salvioli, S Valensin, GD Benedictis, AD Iorio, C Caruso, G Paolisso, D Monti |
Mechanisms of Ageing and Development | 2005 |
Genes and outcome after aneurysmal subarachnoid haemorrhage
YM Ruigrok, AJ Slooter, A Bardoel, CJ Frijns, GJ Rinkel, C Wijmenga |
Journal of Neurology | 2005 |
Interleukin-6 genotype is associated with high-density lipoprotein cholesterol responses to exercise training
A Halverstadt, DA Phares, S Roth, RE Ferrell, AP Goldberg, JM Hagberg |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2005 |
Interaction between interleukin?6 and intercellular adhesion molecule?1 genes and Alzheimer?s disease risk
O Combarros, J Infante, J Llorca, N Pea, C Fernndez-Viadero, J Berciano |
Journal of Neurology | 2005 |
Single Nucleotide Polymorphisms in the Interleukin-6 Gene Associated with Blood Pressure and Atherosclerosis in a Japanese General Population
C TANAKA, T MANNAMI, K KAMIDE, S TAKIUCHI, Y KOKUBO, T KATSUYA, Y KAWANO, T MIYATA, T OGIHARA, H TOMOIKE |
Hypertension Research | 2005 |
Biology of Depression: From Novel Insights to Therapeutic Strategies
J Licinio, ML Wong |
2005 | |
Effect of genetic modifiers on cerebral lesions in Fabry disease
G Altarescu, DF Moore, R Schiffmann |
Neurology | 2005 |
Association tests of interleukin-6 (IL-6) and type II tumor necrosis factor receptor (TNFR2) genes with bone mineral density in Caucasians using a re-sampling approach.
Xiao P, Liu PY, Lu Y, Guo YF, Xiong DH, Li LH, Recker RR, Deng HW |
Human Genetics | 2005 |
Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases?
M Bennermo, C Held, S Stemme, CG Ericsson, A Silveira, F Green, P Tornvall |
Clinical chemistry | 2004 |
Cooperative influence of the interleukin-6 promoter polymorphisms -597, -572 and -174 on long-term kidney allograft survival
M Müller-Steinhardt, L Fricke, B Müller, B Ebel, H Kirchner, C Härtel |
American Journal of Transplantation | 2004 |
Non-HLA immunogenetic polymorphisms and the risk of complications after allogeneic hemopoietic stem-cell transplantation
C Mullighan, S Heatley, K Doherty, F Szabo, A Grigg, T Hughes, A Schwarer, J Szer, B Tait, B To, P Bardy |
Transplantation | 2004 |
Increased expression of IL-6 and RANK mRNA in human trabecular bone from fragility fracture of the femoral neck
H Tsangari, DM Findlay, JS Kuliwaba, GJ Atkins, NL Fazzalari |
Bone | 2004 |
Blasts from the past
PA Insel, S Kornfeld, PW Majerus, AR Marks, PA Marks, AS Relman, BF Scharschmidt, TP Stossel, AP Varki, SJ Weiss, JD Wilson |
Journal of Clinical Investigation | 2004 |
Innate immunity genes influence the severity of acute appendicitis
FA Rivera-Chavez, DL Peters-Hybki, RC Barber, GM Lindberg, I Jialal, RS Munford, GE O'Keefe |
Annals of Surgery | 2004 |
The IL-6 G-174C polymorphism may be associated with ischaemic stroke in patients without a history of hypertension
J Balding, WJ Livingstone, SJ Pittock, L Mynett-Johnson, T Ahern, A Hodgson, OP Smith |
Irish Journal of Medical Science | 2004 |
Role of cytokine gene polymorphism and hepatic transforming growth factor β1 expression in recurrent hepatitis C after liver transplantation
Z Ben-Ari, O Pappo, T Druzd, J Sulkes, T Klein, Z Samra, R Gadba, AR Tambur, R Tur-Kaspa, E Mor |
Cytokine | 2004 |
Genetic risk factors for stroke and carotid atherosclerosis: insights into pathophysiology from candidate gene approaches
SE Humphries, L Morgan |
The Lancet Neurology | 2004 |
Genomic polymorphisms in sepsis
MT Lin, TE Albertson |
Critical Care Medicine | 2004 |
Cytokine gene polymorphism and immunoregulation in periodontal disease
JJ Taylor, PM Preshaw, PT Donaldson |
Periodontology 2000 | 2004 |
Cytokine gene polymorphisms in ischaemic heart disease: investigation using family-based tests of association
PG McGlinchey, MS Spence, CC Patterson, AR Allen, G Murphy, DA Savage, AP Maxwell, PP McKeown |
Journal of Molecular Medicine | 2004 |
Renovascular disease is associated with low producer genotypes of the anti-inflammatory cytokine interleukin-10
S George, XZ Ruan, C Navarrete, D Turner, M Reynard, P Sweny, G Hamilton, DC Wheeler, SH Powis, JF Moorhead, Z Varghese |
Tissue Antigens | 2004 |
Inflammatory bowel disease: the role of inflammatory cytokine gene polymorphisms
J Balding, WJ Livingstone, J Conroy, L Mynett-Johnson, DG Weir, N Mahmud, OP Smith |
Mediators of Inflammation | 2004 |
Elevated white cell count in acute coronary syndromes: relationship to variants in inflammatory and thrombotic genes
CE Byrne, A Fitzgerald, CP Cannon, DJ Fitzgerald, DC Shields |
BMC Medical Genetics | 2004 |
An interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes
JW Stephens, SJ Hurel, J Acharya, SE Humphries |
Cardiovascular Diabetology | 2004 |
The -174 G/C gene polymorphism in interleukin-6 is associated with an aggressive breast cancer phenotype
B Iacopetta, F Grieu, D Joseph |
British Journal of Cancer | 2004 |
Association of the G-174C Variant in the Interleukin-6 Promoter Region With Bone Loss and Fracture Risk in Older Women
SP Moffett, JM Zmuda, JA Cauley, KL Stone, MC Nevitt, KE Ensrud, TA Hillier, MC Hochberg, G Joslyn, P Morin, SR Cummings |
Journal of Bone and Mineral Research | 2004 |
Influence of Cytokine Gene Polymorphisms on Focal Segmental Glomerulosclerosis
C Bantis, PJ Heering, Y Luther, S Aker, N Kuhr, B Grabensee, K Ivens |
American Journal of Nephrology | 2004 |
Injury research in the genomic era
JP Cobb, GE O'Keefe |
The Lancet | 2004 |
Cytokine gene polymorphisms in hemodialysis patients: Association with comorbidity, functionality, and serum albumin
VS Balakrishnan, D Guo, M Rao, BL Jaber, H Tighiouart, RL Freeman, C Huang, AJ King, BJ Pereira |
Kidney International | 2004 |
Interactions of Interleukin-6 Promoter Polymorphisms With Dietary and Lifestyle Factors and Their Association With Bone Mass in Men and Women From the Framingham Osteoporosis Study
SL Ferrari, D Karasik, J Liu, S Karamohamed, AG Herbert, LA Cupples, DP Kiel |
Journal of Bone and Mineral Research | 2004 |
Advances in the genomics of allogeneic haemopoietic stem cell transplantation
CG Mullighan, PG Bardy |
Drug Development Research | 2004 |
Cytokine gene polymorphisms in endemic pemphigus foliaceus: a possible role for IL6 variants
NF Pereira, JA Hansen, MT Lin, VM Roxo, K Braun, ML Petzl-Erler |
Cytokine | 2004 |
An analysis of CTLA-4 and proinflammatory cytokine genes in Wegener's granulomatosis
Y Zhou, DR Huang, PL Paris, CS Sauter, KA Prock, GS Hoffman |
Arthritis & Rheumatism | 2004 |
Interleukin-6 promoter polymorphism: risk and pathology of Alzheimer's disease
Y Zhang, A Hayes, A Pritchard, U Thaker, M Haque, H Lemmon, J Harris, A Cumming, J Lambert, M Chartierharlin |
Neuroscience Letters | 2004 |
Mutations of Genes Involved in the Innate Immune System as Predictors of Sepsis in Very Low Birth Weight Infants
P Ahrens, E Kattner, B Köhler, C Härtel, J Seidenberg, H Segerer, J Möller, W Göpel |
Pediatric Research | 2004 |
Effect of enalapril and losartan on cytokines in patients with stable angina pectoris awaiting coronary artery bypass grafting and their interaction with polymorphisms in the interleukin-6 gene
J Trevelyan, DJ Brull, EW Needham, HE Montgomery, A Morris, RK Mattu |
The American Journal of Cardiology | 2004 |
Association between TNF-alpha and TGF-beta genotypes in infants and parental history of allergic rhinitis and asthma
DA Gentile, WJ Doyle, A Zeevi, J Howe-Adams, J Trecki, DP Skoner |
Human Immunology | 2004 |
Prognostic value of plasma interleukin-6 concentrations and the -174 G > C and -572 G > C promoter polymorphisms of the interleukin-6 gene in patients with acute myocardial infarction treated with thrombolysis
M Bennermo, C Held, F Green, LE Strandberg, CG Ericsson, LO Hansson, H Watkins, A Hamsten, P Tornvall |
Atherosclerosis | 2004 |
The IL-6 −174G>C polymorphism is associated with cardiovascular diseases and mortality in 80-year-old humans
H Bruunsgaard, L Christiansen, AN Pedersen, M Schroll, T Jørgensen, BK Pedersen |
Experimental Gerontology | 2004 |
Polymorphisms in cytokines and growth factor genes and their association with acute rejection and recurrence of hepatitis C virus disease in liver transplantation: Host genetic factors and outcomes after LTX
VR Mas, RA Fisher, DG Maluf, KJ Archer, MJ Contos, SA Mills, ML Shiffman, DS Wilkinson, L Oliveros, CT Garrett, A Ferreira-Gonzalez |
Clinical Genetics | 2004 |
C-reactive protein levels and common polymorphisms of the interleukin-1 gene cluster and interleukin-6 gene in patients with coronary heart disease
G Latkovskis, N Licis, U Kalnins |
European Journal of Immunogenetics | 2004 |
A common interleukin-6 gene promoter polymorphism influences the clinical characteristics of women with polycystic ovary syndrome
K Walch, C Grimm, R Zeillinger, JC Huber, F Nagele, LA Hefler |
Fertility and Sterility | 2004 |
The effect of recipient cytokine gene polymorphism on cardiac transplantation outcome
IS Gourley, D Denofrio, W Rand, S Desai, E Loh, M Kamoun |
Human Immunology | 2004 |
Association of transforming growth factor ?1 and tumor necrosis factor ? polymorphisms with anti-SSB/La antibody secretion in patients with primary Sj�gren's syndrome
JE Gottenberg, M Busson, P Loiseau, M Dourche, J Cohen-Solal, V Lepage, D Charron, C Miceli, J Sibilia, X Mariette |
Arthritis & Rheumatism | 2004 |
Candidate Gene Studies of Human Pain Mechanisms: Methods for Optimizing Choice of Polymorphisms and Sample Size
I Belfer, T Wu, A Kingman, RK Krishnaraju, D Goldman, MB Max |
Anesthesiology | 2004 |
A common functional variant in the interleukin-6 gene is associated with increased body mass index in subjects with type 2 diabetes mellitus
JW Stephens, SJ Hurel, JA Cooper, J Acharya, GJ Miller, SE Humphries |
Molecular Genetics and Metabolism | 2004 |
Clinical impact of cytokine gene polymorphisms in heart and lung transplantation
CT Holweg, W Weimar, AG Uitterlinden, CC Baan |
The Journal of Heart and Lung Transplantation | 2004 |
Cytokine Gene Polymorphisms in Recurrent Pregnancy Loss of Unknown Cause
N Prigoshin, M Tambutti, J Larriba, S Gogorza, R Testa |
American Journal of Reproductive Immunology | 2004 |
Promoter polymorphism of SLC11A1 (formerly NRAMP1) confers susceptibility to autoimmune type 1 diabetes mellitus in Japanese
K Takahashi, J Satoh, Y Kojima, K Negoro, M Hirai, Y Hinokio, Y Kinouchi, S Suzuki, N Matsuura, T Shimosegawa, Y Oka |
Tissue Antigens | 2004 |
Functional promoter region polymorphism of the proinflammatory chemokine IL-8 gene associates with Parkinson's disease in the Irish
OA Ross, C O'Neill, IM Rea, T Lynch, D Gosal, A Wallace, MD Curran, D Middleton, JM Gibson |
Human Immunology | 2004 |
HLA-DRB1 and -DQB1 alleles and gene polymorphisms of selected cytokines in systemic lupus erythematosus
A Hrycek, U Siekiera, P Cieślik, W Szkróbka |
Rheumatology International | 2004 |
Inflammatory mediators in the elderly
KS Krabbe, M Pedersen, H Bruunsgaard |
Experimental Gerontology | 2004 |
Single nucleotide polymorphisms in the promoter region of the interleukin-6 gene and the risk of recurrent pregnancy loss in japanese women
Y Saijo, F Sata, H Yamada, T Kondo, EH Kato, R Kishi |
Fertility and Sterility | 2004 |
Association of polymorphisms in Th1, Th2 cytokine genes with hayfever and atopy in a subsample of EPIC-Heidelberg
A Nieters, J Linseisen, N Becker |
Cell | 2004 |
Cytokine gene polymorphisms in idiopathic pulmonary fibrosis
RL Riha, IA Yang, GC Rabnott, AM Tunnicliffe, KM Fong, PV Zimmerman |
Internal Medicine Journal | 2004 |
Genetics of juvenile idiopathic arthritis: an update:
S Prahalad |
Current Opinion in Rheumatology | 2004 |
No association of interleukin-6 gene polymorphism (−174 G/C) with myocardial infarction or traditional cardiovascular risk factors
W Lieb, R Pavlik, J Erdmann, B Mayer, SR Holmer, M Fischer, A Baessler, C Hengstenberg, H Loewel, A Doering, GA Riegger, H Schunkert |
International Journal of Cardiology | 2004 |
The IL-6 Gene G-174C Polymorphism Related to Health Indices in Greek Primary School Children**
GV Dedoussis, Y Manios, DM Choumerianou, N Yiannakouris, DB Panagiotakos, K Skenderi, A Zampelas |
Obesity | 2004 |
Periodontitis and atherogenesis: causal association or simple coincidence?. A pilot intervention study
F D'Aiuto, M Parkar, G Andreou, PM Brett, D Ready, MS Tonetti |
Journal of Clinical Periodontology | 2004 |
Analysis of the Interleukin-6 Gene Promoter Polymorphisms in Czech Patients with Chronic Periodontitis
LI Holla, A Fassmann, A Stejskalová, V Znojil, J Vaněk, J Vacha |
Journal of Periodontology | 2004 |
Immunological markers contributing to successful aging in Bulgarians
E Naumova, A Mihaylova, M Ivanova, S Michailova, K Penkova, D Baltadjieva |
Experimental Gerontology | 2004 |
TNF-α, TGF-β, IL-10, IL-6, and INF-γ alleles among African Americans and Cuban Americans. Report of the ASHI minority workshops: Part IV
NL Delaney, V Esquenazi, DP Lucas, AA Zachary, MS Leffell |
Human Immunology | 2004 |
Auto-immuniteit en polymorfismen van het aangeboren en specifieke immuunsysteem
A Royen-Kerkhof, WL Pol, NM Sorge, EA Sanders, W Kuis |
Tijdschrift voor kindergeneeskunde | 2004 |
Immunoregulatory cytokine polymorphisms in Italian patients affected by paroxysmal nocturnal haemoglobinuria and aplastic anaemia
E Fermo, P Bianchi, W Barcellini, P Pedotti, C Boschetti, F Alfinito, A Cortelezzi, A Zanella |
European Journal of Immunogenetics | 2004 |
Host factors impacting the innate response in humans to the candidate adjuvants RC529 and monophosphoryl lipid A
L Tiberio, L Fletcher, JH Eldridge, DD Duncan |
Vaccine | 2004 |
Genetic polymorphisms predicting the outcome of bone marrow transplants
AM Dickinson, PG Middleton, V Rocha, E Gluckman, E Holler |
British Journal of Haematology | 2004 |
Cytokine gene polymorphisms and breast cancer susceptibility and prognosis*
KC Smith, AC Bateman, HM Fussell, WM Howell |
European Journal of Immunogenetics | 2004 |
Interleukin-10 production genotype protects against acute persistent rejection after lung transplantation
HX Zheng, GJ Burckart, K McCurry, S Webber, J Ristich, A Iacono, J Dauber, K McDade, W Grgurich, D Zaldonis, G Pillage, BP Griffith, A Zeevi |
The Journal of Heart and Lung Transplantation | 2004 |
Interleukin-10 and interleukin-6 gene polymorphisms as risk factors for Alzheimer’s disease
B Arosio, D Trabattoni, L Galimberti, P Bucciarelli, F Fasano, C Calabresi, CL Cazzullo, C Vergani, G Annoni, M Clerici |
Neurobiology of Aging | 2004 |
Interleukin 6 −174 G/C promoter gene polymorphism in centenarians: no evidence of association with human longevity or interaction with apolipoprotein E alleles
C Capurso, V Solfrizzi, A D'Introno, AM Colacicco, SA Capurso, C Semeraro, A Capurso, F Panza |
Experimental Gerontology | 2004 |
Th2/Th3 cytokine genotypes are associated with pregnancy loss
PA Costeas, A Koumouli, A Giantsiou-Kyriakou, A Papaloizou, L Koumas |
Human Immunology | 2004 |
Interleukin 6-174 G/C promoter gene polymorphism and sporadic Alzheimer's disease: geographic allele and genotype variations in Europe
C Capurso, V Solfrizzi, A D'Introno, AM Colacicco, SA Capurso, A Capurso, F Panza |
Experimental Gerontology | 2004 |
Heterozygote AG variant of −596 A/G IL-6 gene polymorphism is a marker for cutaneous T-cell lymphoma (CTCL)
JA Vasku, A Vasku, M Goldbergova, V Vasku |
Clinical Immunology | 2004 |
Analysis of common IL-6 promoter SNP variants and the AnTn tract in humans and primates and effects on plasma IL-6 levels following coronary artery bypass graft surgery
D Kelberman, M Fife, MV Rockman, DJ Brull, P Woo, SE Humphries |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2004 |
Interleukin-6 promoter polymorphism is associated with bone quality assessed by calcaneus ultrasound and previous fractures in a cohort of 75-year-old women
A Nordstr�m, P Gerdhem, H Br�ndstr�m, F Stiger, UH Lerner, M Lorentzon, K Obrant, P Nordstr�m, K �kesson |
Osteoporosis International | 2004 |
Periodontitis and Systemic Inflammation: Control of the Local Infection is Associated with a Reduction in Serum Inflammatory Markers
F DAiuto, M Parkar, G Andreou, J Suvan, PM Brett, D Ready, MS Tonetti |
Journal of dental research | 2004 |
Association of G-174C Polymorphism of the Interleukin-6 Gene Promoter with Graves' Ophthalmopathy
T Bednarczuk, A Kuryłowicz, Y Hiromatsu, J Kiljański, A Telichowska, J Nauman |
Autoimmunity | 2004 |
Polymorphisms of genes involved in innate immunity: association with preterm delivery
C Härtel, D Finas, P Ahrens, E Kattner, T Schaible, D Müller, H Segerer, K Albrecht, J Möller, K Diedrich, W Göpel |
Molecular Human Reproduction | 2004 |
Lack of IFN-gamma 2/2 homozygous genotype independently of recipient age and intensity of conditioning regimen influences the risk of aGVHD manifestation after HLA-matched sibling haematopoietic stem cell transplantation
A Mlynarczewska, B Wysoczanska, L Karabon, K Bogunia-Kubik, A Lange |
Bone Marrow Transplantation | 2004 |
A common polymorphism in the interleukin-6 gene promoter is associated with overweight
I Wernstedt, AL Eriksson, A Berndtsson, J Hoffstedt, S Skrtic, T Hedner, LM Hultén, O Wiklund, C Ohlsson, JO Jansson |
International Journal of Obesity | 2004 |
Independent association between inflammatory markers (C-reactive protein, interleukin-6 and TNF-α) and essential hypertension
LE Bautista, LM Vera, IA Arenas, G Gamarra |
Journal of Human Hypertension | 2004 |
Biological variations, genetic polymorphisms and familial resemblance of TNF-α and IL-6 concentrations: STANISLAS cohort
N Haddy, C Sass, S Maumus, B Marie, S Droesch, G Siest, D Lambert, S Visvikis |
European Journal of Human Genetics | 2004 |
The −174 G/C gene polymorphism in interleukin-6 is associated with an aggressive breast cancer phenotype
B Iacopetta, F Grieu, D Joseph |
British Journal of Cancer | 2004 |
Genetic susceptibility to tobacco-related cancer
X Wu, H Zhao, R Suk, DC Christiani |
Oncogene | 2004 |
Differential cytokine genotype frequencies among Canadian Aboriginal and Caucasian populations
L Larcombe, JD Rempel, I Dembinski, K Tinckam, C Rigatto, P Nickerson |
Genes and Immunity | 2004 |
Epistatic effects of genes encoding immunoglobulin GM allotypes and interleukin-6 on the production of autoantibodies to 60- and 65-kDa heat-shock proteins
JP Pandey, Z Prohászka, A Veres, G Füst, M Hurme |
Genes and Immunity | 2004 |
Influence of the interleukin-6 −174 G/C gene polymorphism on exercise training-induced changes in glucose tolerance indexes
JA McKenzie, EP Weiss, IA Ghiu, O Kulaputana, DA Phares, RE Ferrell, JM Hagberg |
Journal of applied physiology | 2004 |
The interleukin-6 gene: a susceptibility factor that may contribute to racial and ethnic disparities in breast cancer mortality
FG Berger |
Breast Cancer Research and Treatment | 2004 |
Racial disparities in female breast cancer in South Carolina: clinical evidence for a biological basis
JE Cunningham, WM Butler |
Breast Cancer Research and Treatment | 2004 |
Interindividual variation in the response by fibrinogen, C-reactive protein and interleukin-6 to yellow fever vaccination:
M Verschuur, MT van der Beek, HS Tak, LG Visser, MP de Maat |
Blood Coagulation & Fibrinolysis | 2004 |
Modest implication of interleukin-6 promoter polymorphisms in longevity
L Christiansen, L Bathum, K Andersen-Ranberg, B Jeune, K Christensen |
Mechanisms of Ageing and Development | 2004 |
Nutrition and Bone Health
MF Holick, B Dawson-Hughes |
2004 | |
Immunobiology of Organ Transplantation
DS Wilkes, WJ Burlingham |
2004 | |
Schizophrenie
HJ Möller, N Müller |
2004 | |
Novel twin study implicates IL-6 in the etiology of young adult Hodgkin lymphoma
JR Cerhan |
Blood | 2004 |
Body Mass Index and C-174G Interleukin-6 Promoter Polymorphism Interact in Predicting Type 2 Diabetes
M Möhlig, H Boeing, J Spranger, M Osterhoff, A Kroke, E Fisher, MM Bergmann, M Ristow, K Hoffmann, AF Pfeiffer |
The Journal of clinical endocrinology and metabolism | 2004 |
The Interleukin-6 G(−174)C Promoter Polymorphism Does Not Determine Plasma Interleukin-6 Concentrations in Experimental Endotoxemia in Humans
G Endler, C Marsik, C Joukhadar, R Marculescu, F Mayr, C Mannhalter, OF Wagner, B Jilma |
Clinical chemistry | 2004 |
HLA-DRB1 and -DQB1 alleles and gene polymorphisms of selected cytokines in systemic lupus erythematosus.
Hrycek A, Siekiera U, Cieślik P, Szkróbka W |
Rheumatology International | 2004 |
IL-6-174G/C genotype is associated with the bone mineral density response to oestrogen replacement therapy in post-menopausal women.
James L, Onambele G, Woledge R, Skelton D, Woods D, Eleftheriou K, Hawe E, Humphries SE, Haddad F, Montgomery H |
European Journal of Applied Physiology | 2004 |
IL-1 alpha (-889) promoter polymorphism is a risk factor for osteomyelitis
V Asensi, V Alvarez, E Valle, A Meana, J Fierer, E Coto, JA Carton, JA Maradona, J Paz, MA Dieguez, B la Fuente, A Moreno, S Rubio, MJ Tuya, J Sarasúa, S Llames, JM Arribas |
American journal of medical genetics. Part A | 2003 |
International Textbook of Diabetes Mellitus
RA DeFronzo, L Mandarino, E Ferrannini |
International Textbook of Diabetes Mellitus | 2003 |
Biologic therapies for juvenile arthritis
N Wilkinson, G Jackson, J Gardner-Medwin |
Archives of disease in childhood | 2003 |
Interleukin-6 promoter haplotypes and interleukin-6 cytokine responses
FA Rivera-Chavez, DL Peters-Hybki, RC Barber, GE O'Keefe |
Shock (Augusta, Ga.) | 2003 |
Association of IL-10 polymorphism with severity of illness in community acquired pneumonia
PM Gallagher, G Lowe, T Fitzgerald, A Bella, CM Greene, NG McElvaney, SJ O'Neill |
Thorax | 2003 |
Cytokine gene polymorphisms associated with symptomatic parvovirus B19 infection
JR Kerr, M McCoy, B Burke, DL Mattey, V Pravica, IV Hutchinson |
Journal of clinical pathology | 2003 |
Interleukin-6 (IL6) Genotype Is Associated With Fat-Free Mass in Men But Not Women
SM Roth, MA Schrager, MR Lee, EJ Metter, BF Hurley, RE Ferrell |
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences | 2003 |
Genetic variability and transplantation
B Marder, B Schröppel, B Murphy |
Current Opinion in Urology | 2003 |
The therapeutic potential of interleukin-6 in treating obesity
K Wallenius, JO Jansson, V Wallenius |
Expert Opinion on Biological Therapy | 2003 |
Cytokine response to endotoxin in individuals heterozygous for the Δ32 mutation of chemokine receptor CCR5
M Heesen, EF Schippers, B Bloemeke, D Kunz, JT van Dissel |
Cytokine | 2003 |
C-reactive protein and interleukin-6 in vascular disease
M Rattazzi, M Puato, E Faggin, B Bertipaglia, A Zambon, P Pauletto |
Journal of Hypertension | 2003 |
Cytokine gene polymorphisms moderate illness severity in infants with respiratory syncytial virus infection
DA Gentile, WJ Doyle, A Zeevi, J Howe-Adams, S Kapadia, J Trecki, DP Skoner |
Human Immunology | 2003 |
Genetic variation and hematopoietic stem cell transplantation: expansion of the paradigm
SA Savage, S Chanock |
Pediatric Transplantation | 2003 |
Cytokine levels during symptomatic viral upper respiratory tract infection
DA Gentile, E Villalobos, B Angelini, D Skoner |
Annals of Allergy Asthma & Immunology | 2003 |
Combined analysis of cytokine genotype polymorphism and the level of expression with allograft function in African–American renal transplant patients
DO McDaniel, WH Barber, C Nguyan, SW Rhodes, WL May, LS McDaniel, PJ Vig, LL Jemeson, DE Butkus |
Transplant Immunology | 2003 |
The (−174) G/C polymorphism in the interleukin-6 gene is associated with the severity of acute cerebrovascular events
S Greisenegger, G Endler, D Haering, M Schillinger, W Lang, W Lalouschek, C Mannhalter |
Thrombosis Research | 2003 |
Current concepts of the inflammatory response after major trauma: an update
PV Giannoudis |
Injury | 2003 |
Absence of linkage between the interleukin-6 gene (−174 G/C) polymorphism and migraine
I Rainero |
Neuroscience Letters | 2003 |
The interleukin-6 promoter polymorphism in Gaucher disease: a new modifier gene?
G Altarescu, M Phillips, AJ Foldes, D Elstein, A Zimran, M Mates |
QJM | 2003 |
The role of the interleukin-6 family of cytokines in inflammatory arthritis and bone turnover
PK Wong, IK Campbell, PJ Egan, M Ernst, IP Wicks |
Arthritis & Rheumatism | 2003 |
Impact of pathogen burden in patients with coronary artery disease in relation to systemic inflammation and variation in genes encoding cytokines
JL Georges, HJ Rupprecht, S Blankenberg, O Poirier, C Bickel, G Hafner, V Nicaud, J Meyer, F Cambien, L Tiret |
The American Journal of Cardiology | 2003 |
Cytokine gene polymorphisms in atopic dermatitis
K Reich, G Westphal, IR König, R Mössner, P Schupp, C Gutgesell, E Hallier, A Ziegler, C Neumann |
British Journal of Dermatology | 2003 |
Cytokine gene polymorphisms moderate responses to respiratory syncytial virus in adults
DA Gentile, WJ Doyle, A Zeevi, O Piltcher, DP Skoner |
Human Immunology | 2003 |
Genetic control of postoperative systemic inflammatory reaction and pulmonary and renal complications after coronary artery surgery
M Gaudino, AD Castelnuovo, R Zamparelli, F Andreotti, F Burzotta, L Iacoviello, F Glieca, F Alessandrini, G Nasso, MB Donati, A Maseri, R Schiavello, G Possati |
The Journal of Thoracic and Cardiovascular Surgery | 2003 |
Correlation between transcranial interleukin-6 gradient and outcome in patients with acute brain injury:
E Miñambres, A Cemborain, P Sánchez-Velasco, M Gandarillas, G Díaz-Regañón, U Sánchez-González, F Leyva-Cobián |
Critical Care Medicine | 2003 |
Lower prevalence of IL-4 receptor α-chain gene 1902G variant in very-low-birth-weight infants with necrotizing enterocolitis
A Treszl, E Héninger, A Kálmán, A Schuler, T Tulassay, B Vásárhelyi |
Journal of Pediatric Surgery | 2003 |
Interleukin-6â174 G/C Promoter Gene Polymorphism C Allele Reduces Alzheimer's Disease Risk
F Faltraco, K Bürger, P Zill, SJ Teipel, HJ Möller, H Hampel, B Bondy, M Ackenheil |
Journal of the American Geriatrics Society | 2003 |
Age-Specific Analysis of Normal Cytokine Levels in Healthy Infants
PA Berdat, TJ Wehrle, A Küng, F Achermann, M Sutter, TP Carrel, UE Nydegger |
Clinical chemistry and laboratory medicine : CCLM / FESCC | 2003 |
Association of interleukin-6 -174G/C promoter polymorphism with hypertension and left ventricular hypertrophy in dialysis patients
A Losito, K Kalidas, S Santoni, S Jeffery |
Kidney International | 2003 |
Interleukin-6 gene alleles affect the risk of Alzheimer’s disease and levels of the cytokine in blood and brain
F Licastro, LM Grimaldi, M Bonafè, C Martina, F Olivieri, L Cavallone, S Giovanietti, E Masliah, C Franceschi |
Neurobiology of Aging | 2003 |
Polymorphisms of IL-1B, IL-1RN, IL-2, IL-4, IL-6, IL-10, and IFN-γ genes in the Korean population
CW Pyo, SS Hur, YK Kim, HB Choi, YS Hong, DW Kim, CC Kim, HK Kim, TG Kim |
Human Immunology | 2003 |
Epidemiology of the rheumatic diseases of childhood
PJ Manners |
Current Rheumatology Reports | 2003 |
Polymorphism at position -174 of IL-6 gene is associated with susceptibility to chronic periodontitis in a Caucasian Brazilian population
PC Trevilatto, RM Scarel-Caminaga, RB de Brito, AP de Souza, SR Line |
Journal of Clinical Periodontology | 2003 |
Idiopathic Thrombocytopenic Purpura in Adults:
D Provan, A Newland |
Journal of Pediatric Hematology/Oncology | 2003 |
The role of cytokine gene polymorphisms in the pathogenesis of abdominal aortic aneurysms: A case-control study
MJ Bown, PR Burton, T Horsburgh, ML Nicholson, PR Bell, RD Sayers |
Journal of Vascular Surgery | 2003 |
Racial differences in selected cytokine allelic and genotypic frequencies among healthy, pregnant women in North Carolina
MI Hassan, Y Aschner, CH Manning, J Xu, JL Aschner |
Cytokine | 2003 |
The molecular genetics of cardiovascular disease: clinical implications
JW Stephens, SE Humphries |
Journal of Internal Medicine | 2003 |
Association between -174 G/C polymorphism of interleukin-6 gene and alcoholism
O Sery, R Hladilova, M Novotny, H Hribkova, V Znojil, P Zvolsky |
Acta Neuropsychiatrica | 2003 |
Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma
WM Howell, SJ Turner, JM Theaker, AC Bateman |
European Journal of Immunogenetics | 2003 |
Elucidating the Unexplained Underperformance Syndrome in Endurance Athletes: The Interleukin-6 Hypothesis
PJ Robson |
Sports Medicine | 2003 |
Cytokine gene polymorphisms in allergiccontact dermatitis
GA Westphal, A Schnuch, R Moessner, IR Konig, B Kranke, E Hallier, A Ziegler, K Reich |
Contact Dermatitis | 2003 |
Interleukin-6 Genetic Polymorphisms are not Related to Helicobacter pylori-Associated Gastroduodenal Diseases
IR Hwang, PI Hsu, LE Peterson, O Gutierrez, JG Kim, DY Graham, Y Yamaoka |
Helicobacter | 2003 |
Interleukin-6 promoter −174 polymorphism and spontaneous preterm birth
HN Simhan, MA Krohn, JM Roberts, A Zeevi, SN Caritis |
American Journal of Obstetrics and Gynecology | 2003 |
The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity
Agata Kubaszek, Jussi Pihlajamäki, Kari Punnonen, Pauli Karhapää, Ilkka Vauhkonen, Markku Laakso |
Diabetes | 2003 |
Platelet Counts and Interleukin-6 (IL-6) Promoter Polymorphism in Patients with Gaucher Disease
D Elstein, G Altarescu, A Zimran |
Hematology | 2003 |
Analysis of an Interleukin-6 Gene Promoter Polymorphism in Women With Endometriosis Polymorphism in Women With Endometriosis By Pyrosequencing
F Wieser, G Fabjani, C Tempfer, C Schneeberger, M Sator, J Huber, R Wenzl |
Journal of the Society for Gynecologic Investigation | 2003 |
Genetic Polymorphisms in Sepsis and Septic Shock
CL Holmes, JA Russell, KR Walley |
Chest | 2003 |
Polymorphisms in the 5′-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression
J Duan, AR Sanders, JE Molen, L Martinolich, BJ Mowry, DF Levinson, RR Crowe, JM Silverman, PV Gejman |
Molecular Psychiatry | 2003 |
Genomic polymorphic profiles in an Irish population with meningococcaemia: is it possible to predict severity and outcome of disease?
J Balding, CM Healy, WJ Livingstone, B White, L Mynett-Johnson, M Cafferkey, OP Smith |
Genes and Immunity | 2003 |
Genetic polymorphisms in Spanish rheumatoid arthritis patients: an association and linkage study
A Martinez, M Pascual, D Pascual-Salcedo, A Balsa, J Martin, EG de la Concha |
Genes and Immunity | 2003 |
Genomic analysis of Th1–Th2 cytokine genes in an AIDS cohort: identification of IL4 and IL10 haplotypes associated with the disease progression
A Vasilescu, SC Heath, R Ivanova, H Hendel, H Do, A Mazoyer, E Khadivpour, FX Goutalier, K Khalili, J Rappaport, GM Lathrop, F Matsuda, JF Zagury |
Genes and Immunity | 2003 |
Functional and prognostic relevance of the ?173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis
FD Benedetti, C Meazza, M Vivarelli, F Rossi, A Pistorio, R Lamb, M Lunt, W Thomson, A Ravelli, R Donn, A Martini |
Arthritis & Rheumatism | 2003 |
Cytokine gene polymorphisms in patients infected with hepatitis B virus
Z Ben-Ari, E Mor, O Papo, B Kfir, J Sulkes, AR Tambur, R Tur-Kaspa, T Klein |
The American Journal of Gastroenterology | 2003 |
Recent advances in the management of juvenile idiopathic arthritis
P Woo |
Current Paediatrics | 2003 |
In vitro IL-6 production by EBV-immortalized B lymphocytes from young and elderly people genotyped for −174 C/G polymorphism in IL-6 gene: a model to study the genetic basis of inflamm-aging
F Olivieri, M Bonafè, S Giovagnetti, R Stecconi, M Cardelli, L Cavallone, L Spazzafumo, F Marchegiani, G Carrieri, E Mugianesi, C Giampieri, M Centurelli, R Moresi, S Tesei, R Lisa, C Viticchi, L Falsetti, S Salvioli, C Franceschi |
Mechanisms of Ageing and Development | 2003 |
Polymorphisms in tumour necrosis factor-?, transforming growth factor-?, interleukin-10, interleukin-6, interferon-?, and outcome of hepatitis C virus infection
S Barrett, M Collins, C Kenny, E Ryan, CO Keane, J Crowe |
Journal of Medical Virology | 2003 |
Interleukin-6 Promoter Haplotypes and Interleukin-6 Cytokine Responses:
FA Rivera-Chavez, DL Peters-Hybki, RC Barber, GE O'Keefe |
Shock | 2003 |
Interleukin-6-gene C/G 174 polymorphism in nonagenarian and octogenarian subjects in the BELFAST study. Reciprocal effects on IL-6, soluble IL-6 receptor and for IL-10 in serum and monocyte supernatants
IM Rea, OA Ross, M Armstrong, S McNerlan, DH Alexander, MD Curran, D Middleton |
Mechanisms of Ageing and Development | 2003 |
The ?174G allele of the interleukin-6 gene confers susceptibility to systemic arthritis in children: A multicenter study using simplex and multiplex juvenile idiopathic arthritis families
EM Ogilvie, MS Fife, SD Thompson, N Twine, M Tsoras, M Moroldo, SA Fisher, CM Lewis, AM Prieur, DN Glass, P Woo |
Arthritis & Rheumatism | 2003 |
Cytokines and Chemokines in Autoimmune Disease
P Santamaria |
2003 | |
Inflammation and Cardiac Diseases
GZ Feuerstein, P Libby, DL Mann |
2003 | |
New Developments in Allotransplant Immunology
AJ Barrett, K Rezvani, S Solomon, AM Dickinson, XN Wang, G Stark, H Cullup, M Jarvis, PG Middleton, N Chao |
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program | 2003 |
Association of interleukin-6 promoter variant with bone mineral density in pre-menopausal women
HW Chung, JS Seo, SE Hur, HL Kim, JY Kim, JH Jung, LH Kim, BL Park, HD Shin |
Journal of Human Genetics | 2003 |
The −174G/C Interleukin-6 Polymorphism Influences Postoperative Interleukin-6 Levels and Postoperative Atrial Fibrillation. Is Atrial Fibrillation an Inflammatory Complication?
M Gaudino, F Andreotti, R Zamparelli, AD Castelnuovo, G Nasso, F Burzotta, L Iacoviello, MB Donati, R Schiavello, A Maseri, G Possati |
Circulation | 2003 |
The interleukin-6 (−174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians
B Vozarova, JM Fernández-Real, WC Knowler, L Gallart, RL Hanson, JD Gruber, W Ricart, J Vendrell, C Richart, PA Tataranni, JK Wolford |
Human Genetics | 2003 |
The role of cytokines in prostatitis
TL Jang, AJ Schaeffer |
World Journal of Urology | 2003 |
The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians.
Vozarova B, Fernández-Real JM, Knowler WC, Gallart L, Hanson RL, Gruber JD, Ricart W, Vendrell J, Richart C, Tataranni PA, Wolford JK |
Human Genetics | 2003 |
Association of interleukin-6 promoter variant with bone mineral density in pre-menopausal women.
Chung HW, Seo JS, Hur SE, Kim HL, Kim JY, Jung JH, Kim LH, Park BL, Shin HD |
Journal of Human Genetics | 2003 |
Elucidating the unexplained underperformance syndrome in endurance athletes : the interleukin-6 hypothesis.
Robson P |
Sports medicine (Auckland, N.Z.) | 2003 |
Epidemiology of the rheumatic diseases of childhood.
Manners PJ |
Current Rheumatology Reports | 2003 |
Association of cytokine single nucleotide polymorphisms with B7 costimulatory molecules in kidney allograft recipients
A Hutchings, L Guay-Woodford, JM Thomas, CJ Young, WM Purcell, V Pravica, C Perrey, IV Hutchinson, MR Benfield |
Pediatric Transplantation | 2002 |
The −597 G→A and −174 G→C Polymorphisms in the Promoter of the IL-6 Gene Are Associated with Hyperandrogenism
G Villuendas, JL san Millán, J Sancho, HF Escobar-Morreale |
The Journal of clinical endocrinology and metabolism | 2002 |
Cytokines and juvenile idiopathic arthritis
P Woo |
Current Rheumatology Reports | 2002 |
The effect of the Interleukin-6-174G > C promoter gene polymorphism on endothelial function in healthy volunteers
DJ Brull, CP Lesson, HE Montgomery, M Mullen, M deDivitiis, SE Humphries, JE Deanfield |
European Journal of Clinical Investigation | 2002 |
GENETIC AND ENVIRONMENTAL INFLUENCES ON IL-6 AND TNF-α PLASMA LEVELS IN APPARENTLY HEALTHY GENERAL POPULATION
I Pantsulaia, S Trofimov, E Kobyliansky, G Livshits |
Cytokine | 2002 |
Carotid intima-media thickness is associated with allelic variants of stromelysin-1, interleukin-6, and hepatic lipase genes: the Northern Manhattan Prospective Cohort Study
T Rundek, MS Elkind, J Pittman, B Boden-Albala, S Martin, SE Humphries, SH Juo, RL Sacco |
Stroke; a journal of cerebral circulation | 2002 |
Template-directed dye-terminator incorporation with fluorescence polarization detection for analysis of single nucleotide polymorphisms implicated in sepsis
BD Freeman, TG Buchman, S McGrath, AR Tabrizi, BA Zehnbauer |
The Journal of molecular diagnostics : JMD | 2002 |
Juvenile idiopathic arthritis genetics - what's new? What's next?
W Thomson, R Donn |
Arthritis research | 2002 |
Association between a functional interleukin-6 gene polymorphism and peak bone mineral density and postmenopausal bone loss in women: the ofely study
P Garnero, O Borel, E Sornay-Rendu, F Duboeuf, R Jeffery, P Woo, PD Delmas |
Bone | 2002 |
Polymorphisms in Immunoregulatory Genes
AK Daly, CP Day, PT Donaldson |
American Journal of PharmacoGenomics | 2002 |
The role of the immune system in the insulin resistance syndrome
MR Lewis, RP Tracy |
Current Diabetes Reports | 2002 |
Can the interleukin-6 response to endotoxin be predicted? Studies of the influence of a promoter polymorphism of the interleukin-6 gene, gender, the density of the endotoxin receptor CD14, and inflammatory cytokines
M Heesen, B Bloemeke, N Heussen, D Kunz |
Critical Care Medicine | 2002 |
The interleukin-6 −174promoter polymorphism is associated with long-term kidney allograft survival
M Müller-Steinhardt, C Härtel, B Müller, H Kirchner, L Fricke |
Kidney International | 2002 |
The −174 C/G locus affects in vitro/in vivo IL-6 production during aging
F Olivieri, M Bonafè, L Cavallone, S Giovagnetti, F Marchegiani, M Cardelli, E Mugianesi, C Giampieri, R Moresi, R Stecconi, R Lisa, C Franceschi |
Experimental Gerontology | 2002 |
Levels of IL-6 and soluble IL-6 receptor are increased in HIV patients with a history of immune restoration disease after HAART
SF Stone, P Price, NM Keane, RJ Murray, MA French |
HIV Medicine | 2002 |
Myeloma aetiology and epidemiology
GJ Morgan, FE Davies, M Linet |
Biomedicine & Pharmacotherapy | 2002 |
A -174G/C polymorphism of the interleukin-6 gene in patients with lacunar infarction
M Revilla |
Neuroscience Letters | 2002 |
Advances in Cell Aging and Gerontology
T Fülöp, K Hirokawa, G Dupuis, A Larbi, G Pawelec |
Advances in Cell Aging and Gerontology | 2002 |
IL-6 in autoimmune disease and chronic inflammatory proliferative disease
K Ishihara, T Hirano |
Cytokine & Growth Factor Reviews | 2002 |
Omega-3 Fatty Acids in Inflammation and Autoimmune Diseases
AP Simopoulos |
Journal of the American College of Nutrition | 2002 |
Bone mineral mass is associated with interleukin 1 receptor autoantigen and TNF-α gene polymorphisms in post-menopausal Mediterranean women
R Fontova, C Gutiérrez, J Vendrell, M Broch, I Vendrell, I Simón, JM Fernández-Real, C Richart |
Journal of Endocrinological Investigation | 2002 |
The −174 G/C Polymorphism of the Interleukin-6 Gene Promoter is Associated with Peripheral Artery Occlusive Disease
A Flex, E Gaetani, R Pola, A Santoliquido, F Aloi, P Papaleo, AD Lago, E Pola, M Serricchio, P Tondi, P Pola |
European Journal of Vascular and Endovascular Surgery | 2002 |
Interleukin-6 polymorphism (-634C/G) in the promotor region and the progression of diabetic nephropathy in Type 2 diabetes
A Kitamura, G Hasegawa, H Obayashi, K Kamiuchi, M Ishii, M Yano, T Tanaka, M Yamaguchi, H Shigeta, M Ogata, N Nakamura, T Yoshikawa |
Diabetic Medicine | 2002 |
Frequency of cytokine polymorphisms in populations from western Europe, Africa, Asia, the Middle East and South America
A Meenagh, F Williams, OA Ross, C Patterson, C Gorodezky, M Hammond, WA Leheny, D Middleton |
Human Immunology | 2002 |
Cytokine Polymorphisms in Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Association with Diagnosis and Treatment Response
DA Shoskes, Q Albakri, K Thomas, D Cook |
The Journal of Urology | 2002 |
Polymorphism of the cytokine genes and IgA nephropathy
J Syrjanen, M Hurme, T Lehtimaki, J Mustonen, A Pasternack |
Kidney International | 2002 |
The –74 G/C polymorphism of the interleukin-6 gene promoter is associated with Alzheimerʼs disease in an Italian population:
R Pola, A Flex, E Gaetani, AD Lago, L Gerardino, P Pola, R Bernabei |
NeuroReport | 2002 |
THE −174 G TO C POLYMORPHISM OF INTERLEUKIN-6 GENE IS VERY RARE IN KOREANS
CS Lim, S Zheng, YS Kim, C Ahn, JS Han, S Kim, JS Lee, DW Chae |
Cytokine | 2002 |
Polymorphisms in cytokine genes define subpopulations of HIV-1 patients who experienced immune restoration diseases:
P Price, G Morahan, D Huang, E Stone, KY Cheong, A Castley, M Rodgers, MQ McIntyre, LJ Abraham, MA French |
AIDS | 2002 |
Ethnicity Greatly Influences Cytokine Gene Polymorphism Distribution
SC Hoffmann, EM Stanley, ED Cox, BS DiMercurio, DE Koziol, DM Harlan, AD Kirk, PJ Blair |
American Journal of Transplantation | 2002 |
Effect of the interleukin-6 promoter polymorphism (−174 G/C) on the incidence and outcome of sepsis:
B Schlüter, C Raufhake, M Erren, H Schotte, F Kipp, S Rust, HV Aken, G Assmann, E Berendes |
Critical Care Medicine | 2002 |
Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease
G Endler, A Klimesch, H Sunder-Plassmann, M Schillinger, M Exner, C Mannhalter, N Jordanova, G Christ, R Thalhammer, K Huber, R Sunder-Plassmann |
British Journal of Haematology | 2002 |
Thalidomide therapy for recalcitrant systemic onset juvenile rheumatoid arthritis
TJ Lehman, KH Striegel, KB Onel |
The Journal of Pediatrics | 2002 |
−174 G/C interleukin-6 gene polymorphism and increased risk of multi-infarct dementia: a case-control study
R Pola, E Gaetani, A Flex, F Aloi, P Papaleo, L Gerardino, DD Martini, R Flore, P Pola, R Bernabei |
Experimental Gerontology | 2002 |
Interleukin-10, interleukin-6 and interferon-γ gene polymorphisms in melanoma patients:
JA Martínez-Escribano, MR Moya-Quiles, M Muro, O Montes-Ares, T Hernández-Caselles, JF Frías, MR Álvarez-López |
Melanoma Research | 2002 |
Symposium on ’Nutrition in the post-genomic era’ Plenary session 4: Genetic variation and diet-related disease
WM Howell, PC Calder, RF Grimble |
Proceedings of the Nutrition Society | 2002 |
The immunological synapse
RJ Creusot, NA Mitchison, NM Terazzini |
Molecular Immunology | 2002 |
Allele frequencies of polymorphisms of TNFA, IL-6, IL-10 and IFNG in an Italian Caucasian population
F Poli, A Nocco, S Berra, M Scalamogna, E Taioli, E Longhi, G Sirchia |
European Journal of Immunogenetics | 2002 |
The role of transsignalling via the agonistic soluble IL-6 receptor in human diseases
Karl-Josef Kallen |
Biochimica et Biophysica Acta | 2002 |
Tumor necrosis factor receptor type II (exon 6) and interleukin-6 (−174) gene polymorphisms are not associated with family history but tumor necrosis factor receptor type II is associated with hypertension in patients with rheumatoid arthritis from northe: Concise Communications
SR Dahlqvist, L Ärlestig, C Sikström, S Linghult |
Arthritis & Rheumatism | 2002 |
The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists
DC Shields, AP Fitzgerald, PA O'Neill, C Muckian, D Kenny, B Moran, CP Cannon, CE Byrne, DJ Fitzgerald |
The Pharmacogenomics Journal | 2002 |
The −174 G/C polymorphism of the interleukin-6 gene promoter and essential hypertension in an elderly Italian population
R Pola, A Flex, E Gaetani, P Pola, R Bernabei |
Journal of Human Hypertension | 2002 |
A detailed genetic map of the chromosome 7 bronchial hyper-responsiveness locus
NI Leaves, S Bhattacharyya, S Wiltshire, WO Cookson |
European Journal of Human Genetics | 2002 |
IL-1B and IL-6 gene polymorphisms encode significant risk for the development of recurrent aphthous stomatitis (RAS)
MR Bazrafshani, AH Hajeer, WE Ollier, MH Thornhill |
Genes and Immunity | 2002 |
Safe disposal of inflammatory monosodium urate monohydrate crystals by differentiated macrophages
RC Landis, DR Yagnik, O Florey, P Philippidis, V Emons, JC Mason, DO Haskard |
Arthritis & Rheumatism | 2002 |
Cerebrospinal fluid levels of ??-amyloid(42) in patients with Alzheimer??s disease are related to the exon 2 polymorphism of the cathepsin D gene:
A Papassotiropoulos, HD Lewis, M Bagli, F Jessen, U Ptok, A Schulte, MS Shearman, R Heun |
NeuroReport | 2002 |
Common Promoter Variant in Cyclooxygenase-2 Represses Gene Expression: Evidence of Role in Acute-Phase Inflammatory Response
A Papafili, MR Hill, DJ Brull, RJ McAnulty, RP Marshall, SE Humphries, GJ Laurent |
Arteriosclerosis, thrombosis, and vascular biology | 2002 |
Interleukin-6 −174G>C Polymorphism and Risk of Coronary Heart Disease in West of Scotland Coronary Prevention Study (WOSCOPS)
F Basso, GD Lowe, A Rumley, AD McMahon, SE Humphries |
Arteriosclerosis, thrombosis, and vascular biology | 2002 |
In the Elderly, Interleukin-6 Plasma Levels and the −174G>C Polymorphism Are Associated With the Development of Cardiovascular Disease
NS Jenny, RP Tracy, MS Ogg, LA Luong, LH Kuller, AM Arnold, AR Sharrett, SE Humphries |
Arteriosclerosis, thrombosis, and vascular biology | 2002 |
Genetic Polymorphisms Influencing Therapy and Susceptibility to Rejection in Organ Allograft Recipients:
F Poli, G Piccolo, M Scalamogna |
BioDrugs | 2002 |
Host defense and inflammatory gene polymorphisms are associated with outcomes after HLA-identical sibling bone marrow transplantation
V Rocha, RF Franco, R Porcher, H Bittencourt, WA Silva, A Latouche, A Devergie, H Espérou, P Ribaud, G Socié, MA Zago, E Gluckman |
Blood | 2002 |
Human gene mutation in pathology and evolution
DN Cooper |
Journal of Inherited Metabolic Disease | 2002 |
Simultaneous genotyping of single nucleotide polymorphisms in the IL-6, IL-10, TNFα and TNFβ genes: Tseng et al : Multiplex-PCR-RFLP
LH Tseng, PJ Chen, MT Lin, K Singleton, EG Martin, AH Yen, SM Chuang, PJ Martin, JA Hansen |
Tissue Antigens | 2002 |
Genetic Influences on Rheumatoid Arthritis in African Americans
LB Hughes, LW Moreland, SL Bridges |
Immunologic Research | 2002 |
The role of the immune system in the insulin resistance syndrome.
Lewis MR, Tracy RP |
Current Diabetes Reports | 2002 |
Bone mineral mass is associated with interleukin 1 receptor autoantigen and TNF-alpha gene polymorphisms in post-menopausal Mediterranean women.
Fontova R, Gutiérrez C, Vendrell J, Broch M, Vendrell I, Simón I, Fernández-Real JM, Richart C |
Journal of Endocrinological Investigation | 2002 |
Cortical bone resorption during exercise is interleukin-6 genotype-dependent.
Dhamrait SS, James L, Brull DJ, Myerson S, Hawe E, Pennell DJ, World M, Humphries SE, Haddad F, Montgomery HE |
European Journal of Applied Physiology | 2002 |
A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity
TD LeVan, JW Bloom, TJ Bailey, CL Karp, M Halonen, FD Martinez, D Vercelli |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
Predisposing factors in the Spondyloarthropathies: New insights into the role of HLA-B27
RA Colbert, S Prahalad |
Current Rheumatology Reports | 2001 |
Preterm labour and delivery: a genetic predisposition
DS Dizon-Townson |
Paediatric and Perinatal Epidemiology | 2001 |
Interleukin-1 receptor antagonist as therapy for inflammatory disorders
BD Freeman, TG Buchman |
Expert Opinion on Biological Therapy | 2001 |
Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study
JS Pankow, AR Folsom, M Cushman, IB Borecki, PN Hopkins, JH Eckfeldt, RP Tracy |
Atherosclerosis | 2001 |
Platelet count and interleukin 6 gene polymorphism in healthy subjects
JM Fernandez-Real, J Vendrell, C Richart, C Gutierrez, W Ricart |
BMC Medical Genetics | 2001 |
Inter-individual differences in cytokine release in patients undergoing cardiac surgery with cardiopulmonary bypass
A Roth-Isigkeit, L Hasselbach, E Ocklitz, S Brückner, A Ros, H Gehring, P Schmucker, L Rink, M Seyfarth |
Clinical & Experimental Immunology | 2001 |
Molecular epidemiology of preterm delivery: methodology and challenges
X Wang, B Zuckerman, G Kaufman, P Wise, M Hill, T Niu, L Ryan, D Wu, X Xu |
Paediatric and Perinatal Epidemiology | 2001 |
Increased cytokine release by leucocytes in survivors of stroke at young age
AJ Grau, M Aulmann, C Lichy, H Meiser, F Buggle, T Brandt, C Grond-Ginsbach |
European Journal of Clinical Investigation | 2001 |
Cytokine gene polymorphisms and susceptibility to juvenile idiopathic arthritis
RP Donn, JH Barrett, A Farhan, A Stopford, L Pepper, E Shelley, N Davies, WE Ollier, W Thomson |
Arthritis & Rheumatism | 2001 |
A gender-dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity
M Bonafè, F Olivieri, L Cavallone, S Giovagnetti, F Marchegiani, M Cardelli, C Pieri, M Marra, R Antonicelli, R Lisa, MR Rizzo, G Paolisso, D Monti, C Franceschi |
European Journal of Immunology | 2001 |
GvHD risk assessment in hematopoietic stem cell transplantation: role of cytokine gene polymorphisms and an in vitro human skin explant model
AM Dickinson, J Cavet, H Cullup, XN Wang, L Sviland, PG Middleton |
Human Immunology | 2001 |
Candidate Genes for Osteoporosis
T Niu, X Xu |
American Journal of PharmacoGenomics | 2001 |
A study of cytokine gene polymorphisms and protein secretion in renal transplantation
NH Cartwright, LJ Keen, AG Demaine, NJ Hurlock, RJ McGonigle, PA Rowe, JF Shaw, RM Szydlo, ER Kaminski |
Transplant Immunology | 2001 |
Determination of cytokine regulatory haplotypes by induced heteroduplex analysis of DNA
NA Wood, LJ Keen, LA Tilley, JL Bidwell |
Journal of Immunological Methods | 2001 |
The −174/−597 promoter polymorphisms in the interleukin-6 gene are not associated with susceptibility to multiple sclerosis
M Fedetz, F Matesanz, M Pascual, J Martı́n, O Fernández, M Guerrero, A Alcina |
Journal of the Neurological Sciences | 2001 |
Role of infection and cytokines in the pathogenesis of chronic obstructive pulmonary disease :
MW Raza, AJ Bint, CC Blackwell |
Reviews in Medical Microbiology | 2001 |
Relation of the −174 G/C polymorphism of interleukin-6 to interleukin-6 plasma levels and to length of hospitalization after surgical coronary revascularization
F Burzotta, L Iacoviello, AD Castelnuovo, F Glieca, N Luciani, R Zamparelli, R Schiavello, MB Donati, A Maseri, GF Possati, F Andreotti |
The American Journal of Cardiology | 2001 |
Atherosclerosis and Autoimmunity
EC Lau |
Atherosclerosis and Autoimmunity | 2001 |
Interleukin-6 (IL-6) and the Prognosis of Abdominal Aortic Aneurysms
KG Jones, DJ Brull, LC Brown, M Sian, RM Greenhalgh, SE Humphries, JT Powell |
Circulation | 2001 |
An Analysis of Acute Changes in Interleukin-6 Levels After Treatment of Hepatitis C with Consensus Interferon
SJ Cotler, KR Reddy, J McCone, DL Wolfe, A Liu, TR Craft, MW Ferris, AJ Conrad, J Albrecht, M Morrissey, DR Ganger, H Rosenblate, LM Blatt, DM Jensen, MW Taylor |
Journal of Interferon & Cytokine Research | 2001 |
The polymorphism at position ???174 of the IL-6 gene is not associated with inflammatory bowel disease:
W Klein, A Tromm, T Griga, H Fricke, C Folwaczny, M Hocke, K Eitner, M Marx, JT Epplen |
European Journal of Gastroenterology & Hepatology | 2001 |
Importance of underlying mechanism and genotype on outcome of sepsis trials:
L McIntyre, KR Walley |
Critical Care Medicine | 2001 |
Immunogenetics and genomics
AV Hill |
The Lancet | 2001 |
The effect of cytokine gene polymorphisms on pediatric heart allograft outcome
MR Awad, S Webber, G Boyle, C Sturchioĉ, M Ahmed, J Martell, Y Law, SA Miller, P Bowman, S Gribar, F Pigula, G Mazariegos, BP Griffith, A Zeevi |
The Journal of Heart and Lung Transplantation | 2001 |
A novel 5?-flanking region polymorphism of macrophage migration inhibitory factor is associated with systemic-onset juvenile idiopathic arthritis
RP Donn, E Shelley, WE Ollier, W Thomson |
Arthritis & Rheumatism | 2001 |
Interleukin 6 and Haemostasis
R Kerr, D Stirling, CA Ludlam |
British Journal of Haematology | 2001 |
The G to C polymorphism at -174 of the interleukin-6 gene is rare in a Southern Chinese population:
R Zhai, G Liu, C Yang, C Huang, C Wu, DC Christiani |
Pharmacogenetics | 2001 |
Interleukin 6, tumour necrosis factor alpha and lymphotoxin alpha polymorphisms in monoclonal gammopathy of uncertain significance and multiple myeloma
AM Dring, FE Davies, SJ Rollinson, PL Roddam, AC Rawstron, JA Child, AS Jack, GJ Morgan |
British Journal of Haematology | 2001 |
INVESTIGATION OF NOVEL POLYMORPHISMS WITHIN THE 3′ REGION OF THE IL-6 GENE IN PATIENTS WITH RHEUMATOID ARTHRITIS USING GENESCAN ANALYSIS
A Crilly, JM Bartlett, A White, D Stirling, H Capell, R Madhok |
Cytokine | 2001 |
Lack of association between human longevity and polymorphisms of IL-1 cluster, IL-6, IL-10 and TNF-α genes in Finnish nonagenarians
XY Wang, M Hurme, M Jylhä, A Hervonen |
Mechanisms of Ageing and Development | 2001 |
ASSOCIATION OF CYTOKINE POLYMORPHIC INHERITANCE AND IN VITRO CYTOKINE PRODUCTION IN ANTI-CD3/CD28-STIMULATED PERIPHERAL BLOOD LYMPHOCYTES1:
SC Hoffmann, EM Stanley, ED Cox, N Craighead, BS DiMercurio, DE Koziol, DM Harlan, AD Kirk, PJ Blair |
Transplantation | 2001 |
TNF-??, IL-6, IFN-??, AND IL-10 GENE EXPRESSION POLYMORPHISMS AND THE IL-4 RECEPTOR ??-CHAIN VARIANT Q576R: EFFECTS ON RENAL ALLOGRAFT OUTCOME:
AB Hahn, JC Kasten-Jolly, DM Constantino, E Graffunder, TP Singh, GK Shen, DJ Conti |
Transplantation | 2001 |
BOTH GENETIC AND CLINICAL FACTORS PREDICT THE DEVELOPMENT OF GRAFT-VERSUS-HOST DISEASE AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION:
G Soci, P Loiseau, R Tamouza, A Janin, M Busson, E Gluckman, D Charron |
Transplantation | 2001 |
ROLE OF CYTOKINE GENE POLYMORPHISM IN HEPATITIS C RECURRENCE AND ALLOGRAFT REJECTION AMONG LIVER TRANSPLANT RECIPIENTS 1:
AR Tambur, JW Ortegel, Z Ben-Ari, E Shabtai, T Klein, R Michowiz, R Tur-Kaspa, E Mor |
Transplantation | 2001 |
CYTOKINE POLYMORPHIC ANALYSES INDICATE ETHNIC DIFFERENCES IN THE ALLELIC DISTRIBUTION OF INTERLEUKIN-2 AND INTERLEUKIN-61:
ED Cox, SC Hoffmann, BS DiMercurio, RA Wesley, DM Harlan, AD Kirk, PJ Blair |
Transplantation | 2001 |
On Genetics, Inflammation, and Abdominal Aortic Aneurysm: Can Single Nucleotide Polymorphisms Predict the Outcome?
AJ Marian |
Circulation | 2001 |
Interleukin-6 Gene −174G>C and −572G>C Promoter Polymorphisms Are Strong Predictors of Plasma Interleukin-6 Levels After Coronary Artery Bypass Surgery
DJ Brull, HE Montgomery, J Sanders, S Dhamrait, L Luong, A Rumley, GD Lowe, SE Humphries |
Arteriosclerosis, thrombosis, and vascular biology | 2001 |
NFκB Polymorphisms and susceptibility to type 1 diabetes
DM Hegazy, DA OReilly, BM Yang, AD Hodgkinson, BA Millward, AG Demaine |
Genes and Immunity | 2001 |
The role of cytokine polymorphisms in rejection after solid organ transplantation
SE Marshall, KI Welsh |
Genes and Immunity | 2001 |
Interleukin 6 gene promoter polymorphism is not associated with Kawasaki disease
MH Sohn, MW Hur, DS Kim |
Genes and Immunity | 2001 |
Interferon-γ and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation
J Cavet, AM Dickinson, J Norden, PR Taylor, GH Jackson, PG Middleton |
Blood | 2001 |
Real-Time PCR Assay with Fluorescent Hybridization Probes for Rapid Interleukin-6 Promoter (−174G→C) Genotyping
T Bertsch, W Zimmer, W Casarin, C Denz, M Quintel, K Fassbender |
Clinical chemistry | 2001 |
Inflammatory bowel disease is associated with a novel promoter polymorphism of natural resistance-associated macrophage protein 1 (NRAMP1) gene: NRAMP1 gene polymorphism
Y Kojima, Y Kinouchi, S Takahashi, K Negoro, N Hiwatashi, T Shimosegawa |
Tissue Antigens | 2001 |
Genetic determinants of IL-6 expression levels do not influence bone loss in inflammatory bowel disease
C Schulte, H Goebell, H D Röher, K M Schulte |
Digestive Diseases and Sciences | 2001 |
Candidate genes and confirmed genetic polymorphisms associated with cardiovascular diseases: a tabular assessment
Z Tang, R P Tracy |
Journal of Thrombosis and Thrombolysis | 2001 |
Use of biologics in the treatment of childhood rheumatic diseases
T Arkachaisri, TJ Lehman |
Current Rheumatology Reports | 2000 |
A Polymorphism in the Promoter Region of the Gene for Interleukin-6 Is Associated with Susceptibility to Type 1 Diabetes Mellitus
MM Jahromi, BA Millward, AG Demaine |
Journal of Interferon & Cytokine Research | 2000 |
Interleukin-6 Gene Polymorphism Is Related to Bone Mineral Density During and After Puberty in Healthy White Males: A Cross-Sectional and Longitudinal Study
M Lorentzon, R Lorentzon, P Nordström |
Journal of Bone and Mineral Research | 2000 |
Single nucleotide polymorphisms and the future of genetic epidemiology
NJ Schork, D Fallin, JS Lanchbury |
Clinical Genetics | 2000 |
Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?
JS Yudkin, M Kumari, SE Humphries, V Mohamed-Ali |
Atherosclerosis | 2000 |
Predictive value of interleukin 1 gene polymorphisms for surgery
A Crilly, N Maiden, HA Capell, R Madhok |
Annals of the rheumatic diseases | 2000 |
Interleukin-6 is an essential, corticotropin-releasing hormone-independent stimulator of the adrenal axis during immune system activation
KE Bethin, SK Vogt, LJ Muglia |
Proceedings of the National Academy of Sciences | 2000 |
Polymorphism in regulatory gene sequences
NA Mitchison |
Genome biology | 2000 |
The development and compensation of biliary cirrhosis in interleukin-6-deficient mice
T Ezure, T Sakamoto, H Tsuji, JG 3rd, N Murase, JJ Fung, AJ Demetris |
The American Journal of Pathology | 2000 |
No association of serum levels of interleukin-6 and its soluble receptor components with a genetic variation in the 3′flanking region of the interleukin-6 gene in patients with multiple sclerosis
S Schmidt |
Neuroscience Letters | 2000 |
Genetic polymorphisms in the cathespin D and interleukin-6 genes and the risk of Alzheimer's disease
TJ Bhojak, ST DeKosky, M Ganguli, MI Kamboh |
Neuroscience Letters | 2000 |
Association between an interleukin-6 promoter and 3′ flanking region haplotype and reduced Alzheimer's disease risk in a German population
M Bagli, A Papassotiropoulos, M Knapp, F Jessen, ML Rao, W Maier, R Heun |
Neuroscience Letters | 2000 |
Neonatal onset of rash in Still’s disease
PH Hoeger, N Veelken, I Foeldvari, M Kurtze, HD Foss |
The Journal of Pediatrics | 2000 |
El aumento de la actividad proinflamatoria es consustancial a la resistencia a la insulina
JM Fernández-Real, W Ricart |
Medicina Clínica | 2000 |
Stromelysin-1 and interleukin-6 gene promoter polymorphisms are determinants of asymptomatic carotid artery atherosclerosis
R Rauramaa, SB Väisänen, LA Luong, A Schmidt-Trücksäss, IM Penttilä, C Bouchard, J Töyry, SE Humphries |
Arteriosclerosis, thrombosis, and vascular biology | 2000 |
An IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in men infected with human immunodeficiency virus
CB Foster, T Lehrnbecher, S Samuels, S Stein, F Mol, JA Metcalf, K Wyvill, SM Steinberg, J Kovacs, A Blauvelt, R Yarchoan, SJ Chanock |
Blood | 2000 |
Variants of Trophic Factors and Expression of Cardiac Hypertrophy in Patients with Hypertrophic Cardiomyopathy
R Patel, DS Lim, D Reddy, SF Nagueh, S Lutucuta, MJ Sole, WA Zoghbi, MA Quiñones, R Roberts, AJ Marian |
Journal of Molecular and Cellular Cardiology | 2000 |
The Development and Compensation of Biliary Cirrhosis in Interleukin-6-Deficient Mice
T Ezure, T Sakamoto, H Tsuji, JG Lunz, N Murase, JJ Fung, AJ Demetris |
The American Journal of Pathology | 2000 |
Interleukin 6, tumour necrosis factor alpha, interleukin 1beta and interleukin 1 receptor antagonist promoter or coding gene polymorphisms in multiple myeloma
CY Zheng, DR Huang, S Bergenbrant, A Sundblad, A Osterborg, M Bjorkholm, G Holm, Q Yi |
British Journal of Haematology | 2000 |
Measurement of Cytokines in Clinical Samples Using Immunoassays: Problems and Pitfalls
RE Banks |
Critical Reviews in Clinical Laboratory Sciences | 2000 |
Cooperative Influence of Genetic Polymorphisms on Interleukin 6 Transcriptional Regulation
CF Terry, V Loukaci, FR Green |
The Journal of biological chemistry | 2000 |
THE IMPACT OF RECIPIENT CYTOKINE GENOTYPE ON ACUTE REJECTION AFTER RENAL TRANSPLANTATION:
SE Marshall, AJ McLaren, NA Haldar, M Bunce, PJ Morris, KI Welsh |
Transplantation | 2000 |
Cytokine Gene Polymorphisms in Autoimmune Thyroid Disease
PJ Hunt, SE Marshall, AP Weetman, JI Bell, JA Wass, KI Welsh |
The Journal of clinical endocrinology and metabolism | 2000 |
Type 1 and type 2 immune responses in children: their relevance in juvenile arthritis
LR Wedderburn, P Woo |
Springer Seminars in Immunopathology | 1999 |
New developments in IL-6 dependent biology and therapy: where do we stand and what are the options?
KJ Kallen, PR Galle, S Rose-John |
Expert Opinion on Investigational Drugs | 1999 |
The genetics of rheumatoid arthritis: Influences on susceptibility, severity, and treatment response
SL Bridges |
Current Rheumatology Reports | 1999 |
Polymorphic haplotypes of the interleukin-10 5? flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis
E Crawley, R Kay, J Sillibourne, P Patel, I Hutchinson, P Woo |
Arthritis & Rheumatism | 1999 |
Biologic therapies in rheumatoid arthritis
KJ Bulpitt |
Current Rheumatology Reports | 1999 |
Mining variations in genes of innate and phagocytic immunity: current status and future prospects
C B Foster, S J Chanock |
Current Opinion in Hematology | 1999 |
Cytokines in children with arthritis
E Crawley, P Woo |
Clinical Immunology Newsletter | 1998 |
Rheumatology
RA Asherson, R Cervera, DP D'Cruz, GR Hughes |
Postgraduate medical journal | 1991 |
Juvenile Idiopathic Arthritis-related Uveitis:
MR Kesen, V Setlur, DA Goldstein |
International Ophthalmology Clinics | |
Septic Shock and Respiratory Failure in Community-acquired Pneumonia Have Different TNF Polymorphism Associations
GW Waterer, MW Quasney, RM Cantor, RG Wunderink |
American journal of respiratory and critical care medicine | 2001 |
Cytokine genotypes in kidney, heart, and lung recipients: consequences for acute and chronic rejection
A Jackson, S Palmer, RD Davis, A Pappendick, E Pearson, K Savik, S Ormaza, M Hertz, M Dacey, L Miller, NL Reinsmoen |
Transplantation Proceedings | 2001 |
TNF-α and IL-6 gene polymorphism and rejection in kidney transplantation recipients
D Reviron, B Dussol, M Andre, P Brunet, P Mercier, Y Berland |
Transplantation Proceedings | 2001 |
Cytokine Polymorphisms in Systemic Lupus Erythematosus and Sjogren's Syndrome
V Magnusson, B Nakken, AI Bolstad, ME Alarcon-Riquelme |
Scandinavian Journal of Immunology | 2001 |
IL-6 POLYMORPHISM, ANTI-IL-6 THERAPY AND ANIMAL MODELS OF MULTIPLE MYELOMA
R Jeffery, NA Mitchison |
Cytokine | 2001 |
A functional polymorphic variant in the interleukin-6 gene promoter associated with low bone resorption in postmenopausal women
SL Ferrari, P Garnero, S Emond, H Montgomery, SE Humphries, SL Greenspan |
Arthritis & Rheumatism | 2001 |
Detection of the single-base substitution ?174 G?C in the interleukin-6 gene by real-time polymerase chain reaction: Comment on the article by Moos et al
N Helmy, FE Maly, L Bestmann |
Arthritis & Rheumatism | 2001 |
Inflamm-aging: An Evolutionary Perspective on Immunosenescence
C Franceschi, M Bonafè, S Valensin, F Olivieri, MD Luca, E Ottaviani, GD Benedictis |
Annals of the New York Academy of Sciences | 2000 |
Identification and efficient genotyping of an (A)n/(T)m polymorphism within the 5' untranslated region of the human IL6 gene
F Tschentscher, A Kalt, V Hoffmann, J Epplen, C Hardt |
European Journal of Immunogenetics | 2000 |
Allelic selection of human IL-2 gene
F Matesanz, C Delgado, M Fresno, A Alcina |
European Journal of Immunology | 2000 |
Polymorphisms at −174 and in the 3′ flanking region of interleukin-6 (IL-6) gene in patients with myasthenia gravis
DR Huang, C Zheng, R Giscombe, G Matell, R Pirskanen, AK Lefvert |
Journal of Neuroimmunology | 1999 |
Polymorphism of the human TNF-α promoter — random variation or functional diversity?
RD Allen |
Molecular Immunology | 1999 |
Plasma IL-8 and IL-6 levels can be used to define a group with low risk of septicaemia among cancer patients with fever and neutropenia
ES de Bont, E Vellenga, JC Swaanenburg, V Fidler, PJ Brummen, WA Kamps |
British Journal of Haematology | 1999 |
Preterm birth and single nucleotide polymorphisms in cytokine genes
Qin Zhu, Jian Sun, Ying Chen |
Translational Pediatrics | |
DAMAGE CONTROL ORTHOPAEDICS: EVOLVING CONCEPTS IN THE TREATMENT OF PATIENTS WHO HAVE SUSTAINED ORTHOPAEDIC TRAUMA
CS Roberts, HC Pape, AL Jones, AL Malkani, JL Rodriguez, PV Giannoudis |
The Journal of Bone and Joint Surgery. American volume. | 2005 |
Genetic Polymorphisms Associated With Susceptibility and Outcome in ARDS
RP Marshall, S Webb, MR Hill, SE Humphries, GJ Laurent |
Chest | 2002 |
Juvenile rheumatoid arthritis as a complex genetic trait
DN Glass, EH Giannini |
Arthritis & Rheumatism | 1999 |
Measuring Plasma Fibrinogen to Predict Stroke and Myocardial Infarction: An Update
G Maresca, AD Blasio, R Marchioli, GD Minno |
Arteriosclerosis, thrombosis, and vascular biology | 1999 |
Critical Care Nephrology
C Ronco, R Bellomo |
1998 | |
Pancreatic Disease
EC Kafka, MH Kalser |
Postgraduate Medicine | 1975 |