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Citations to this article

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis.
D Fishman, … , S Humphries, P Woo
D Fishman, … , S Humphries, P Woo
Published October 1, 1998
Citation Information: J Clin Invest. 1998;102(7):1369-1376. https://doi.org/10.1172/JCI2629.
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The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis.

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Abstract

During active disease, patients with systemic-onset juvenile chronic arthritis (S-JCA) demonstrate a rise and fall in serum interleukin-6 (IL-6) that parallels the classic quotidian fever. To investigate the possibility that this cytokine profile results from a difference in the control of IL-6 expression, we examined the 5' flanking region of the IL-6 gene for polymorphisms. A G/C polymorphism was detected at position -174. In a group of 383 healthy men and women from a general practice in North London, the frequency of the C allele was 0.403 (95% confidence interval 0.37-0.44). In comparison, 92 patients with S-JCA had a different overall genotype frequency, especially those with onset of disease at < 5 yr of age. This was mainly due to the statistically significant lower frequency of the CC genotype in this subgroup. When comparing constructs of the 5' flanking region (-550-+61 bp) in a luciferase reporter vector transiently transfected into HeLa cells, the -174C construct showed 0.624+/-0.15-fold lower expression than the -174G construct. After stimulation with LPS or IL-1, expression from the -174C construct did not significantly change after 24 h, whereas expression from the -174G construct increased by 2.35+/-0.10- and 3.60+/-0.26-fold, respectively, compared with the unstimulated level. Plasma levels of IL-6 were also measured in 102 of the healthy subjects, and the C allele was found to be associated with significantly lower levels of plasma IL-6. These results suggest that there is a genetically determined difference in the degree of the IL-6 response to stressful stimuli between individuals. The reduced frequency of the potentially protective CC genotype in young S-JCA patients may contribute to its pathogenesis. Similarly the individual's IL-6 genotype may be highly relevant in other conditions where IL-6 has been implicated, such as atherosclerosis.

Authors

D Fishman, G Faulds, R Jeffery, V Mohamed-Ali, J S Yudkin, S Humphries, P Woo

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Biochemical Genetics 2021
Pathogenesis of ocular toxoplasmosis
JR Smith, LM Ashander, SL Arruda, CA Cordeiro, S Lie, E Rochet, R Belfort, JM Furtado
Progress in Retinal and Eye Research 2021
Interleukin-6 inhibition: a therapeutic strategy for the management of adult-onset Still’s disease
Y Kaneko, T Takeuchi
Expert Opinion on Biological Therapy 2021
Association between IL-18 and IL-6 gene polymorphisms and the risk of T1D in Egyptian children
YB Ali, HE El-Gahel, NE Abdel-Hakem, ME Gadalla, MH El-Hefnawy, M El-Shahat
Journal of Diabetes & Metabolic Disorders 2021
Polymorphisms of Interleukin-6 and Interleukin-8 Are Not Associated with Parkinson’s Disease in Taiwan
TW Liu, YR Wu, YC Chen, HC Fung, CM Chen
Brain Sciences 2021
Interaction of tobacco chewing and smoking habit with interleukin 6 promoter polymorphism in oral precancerous lesions and oral cancer
Y Shahi, S Mukherjee, FM Samadi
European Archives of Oto-Rhino-Laryngology 2021
The relationship between polymorphism of interleukin-6 and osteoprotgerin genes with dental peri-implant disease: A meta-analysis
P Motahari, A Rasi
Gene Reports 2021
Association of NFκβ, TNFα, IL-6, IL-1β, and LPL Polymorphisms with Type 2 Diabetes Mellitus and Biochemical Parameters in a Mexican Population
OC Martínez-Ramírez, DA Salazar-Piña, RG de Lorena, C Castro-Hernández, L Casas-Ávila, JA Portillo-Jacobo, J Rubio
Biochemical Genetics 2021
Th1 cytokine gene polymorphism and the corresponding plasma cytokine levels: A comparative study in HIV‐1 positive and exposed uninfected infants
V Chavan, S Ahir, S Kerkar, Z Ansari, P SamantMavani, R Nanavati, P Mehta, J ManiaPramanik
Journal of Medical Virology 2021
Cytokine Overproduction and Immune System Dysregulation in alloHSCT and COVID-19 Patients
A Lange, J Lange, E Jaskuła
Frontiers in immunology 2021
Relationship Between Interleukin-6 −174G/C Genetic Variant and Efficacy of Methotrexate Treatment in Psoriatic Arthritis Patients
R Sokolik, M Iwaszko, J Świerkot, B Wysoczańska, L Korman, P Wiland, K Bogunia-Kubik
Pharmacogenomics and Personalized Medicine 2021
Association of Genetic Polymorphisms and Serum Levels of IL-6 and IL-8 with the Prognosis in Children with Neuroblastoma
SS Moreno-Guerrero, A Ramírez-Pacheco, LM Rocha-Ramírez, G Hernández-Pliego, P Eguía-Aguilar, MA Escobar-Sánchez, A Reyes-López, LE Juárez-Villegas, JJ Sienra-Monge
Cancers 2021
Current and emerging biological therapy in adult-onset Still’s disease
Y Ma, J Meng, J Jia, M Wang, J Teng, D Zhu, C Yang, Q Hu
Rheumatology 2021
Acute Pancreatitis: Genetic Risk and Clinical Implications
FU Weiss, F Laemmerhirt, MM Lerch
Journal of Clinical Medicine 2021
Association of recipient and donor interleukin 6 polymorphisms 174 and 597 with outcome after allogeneic hematopoietic stem cell transplantation in children
L Wetzel, S Wittig, B Gruhn
Journal of Cancer Research and Clinical Oncology 2021
Risk of Recurrent Pregnancy Loss in the Ukrainian Population Using a Combined Effect of Genetic Variants: A Case-Control Study.
Loizidou EM, Kucherenko A, Tatarskyy P, Chernushyn S, Livshyts G, Gulkovskyi R, Vorobiova I, Antipkin Y, Gorodna O, Kaakinen MA, Prokopenko I, Livshits L
Genes & development 2021
Association of NFκβ, TNFα, IL-6, IL-1β, and LPL Polymorphisms with Type 2 Diabetes Mellitus and Biochemical Parameters in a Mexican Population.
Martínez-Ramírez OC, Salazar-Piña DA, de Lorena RM, Castro-Hernández C, Casas-Ávila L, Portillo-Jacobo JA, Rubio J
Biochemical Genetics 2021
Polymorphisms of Interleukin-6 and Interleukin-8 Are Not Associated with Parkinson's Disease in Taiwan.
Liu TW, Wu YR, Chen YC, Fung HC, Chen CM
Brain Sciences 2021
Association between IL-18 and IL-6 gene polymorphisms and the risk of T1D in Egyptian children.
Ali YBM, El-Gahel HE, Abdel-Hakem NE, Gadalla ME, El-Hefnawy MH, El-Shahat M
2021
Analysis of association between MALAT1 haplotype and the severity of normal-tension glaucoma (NTG).
Yue JL, Zheng SF
Journal of Cellular and Molecular Medicine 2021
Polymorphism of interleukin-6 -174 G/C (rs1800795) & the corresponding interleukin-6 level as a prognostic marker of cervical cancer.
Wagh P, Kulkarni P, Kerkar S, Tongaonkar H, Chaudhari H, Warke H, Deodhar K, Rekhi B, Mania-Pramanik J
The Indian journal of medical research 2021
Association between single nucleotide polymorphisms of IL-6 and susceptibility to skin cancer: a meta-analysis and systematic review.
Guo K, Lu Z, Wang X, Qiao J
Translational cancer research 2021
Genetic characteristics of competitive swimmers: a review.
Ben-Zaken S, Eliakim A, Nemet D, Kaufman L, Meckel Y
Biology of Sport 2021
Interactions of genetic variants and prenatal stress in relation to the risk for recurrent respiratory infections in children.
Korhonen LS, Lukkarinen M, Kantojärvi K, Räty P, Karlsson H, Paunio T, Peltola V, Karlsson L
Scientific Reports 2021
Interplay between IL6 and CRIM1 in thiopurine intolerance due to hematological toxicity in leukemic patients with wild-type NUDT15 and TPMT.
Kim H, You S, Park Y, Choi JY, Ma Y, Hong KT, Koh KN, Yun S, Lee KH, Shin HY, Lee S, Yoo KH, Im HJ, Kang HJ, Kim JH
Scientific Reports 2021
Analysis of transcriptomic data sets supports the role of IL-6 in NETosis and immunothrombosis in severe COVID-19.
Mukhopadhyay S, Sinha S, Mohapatra SK
2021
The Association of IL-6, TNFα and CRP Gene Polymorphisms with Coronary Artery Disease in a Tunisian Population: A Case-Control study.
Grira N, Lahidheb D, Lamine O, Ayoub M, Wassaifi S, Aouni Z, Fehri W, Mazigh C
Biochemical Genetics 2021
Interleukin 6 (rs1800795) and pentraxin 3 (rs2305619) polymorphisms-association with inflammation and all-cause mortality in end-stage-renal disease patients on dialysis.
Rocha S, Valente MJ, Coimbra S, Catarino C, Rocha-Pereira P, Oliveira JG, Madureira J, Fernandes JC, do Sameiro-Faria M, Miranda V, Belo L, Santos-Silva A, Bronze-da-Rocha E
Scientific Reports 2021
The polymorphisms of IL-6/STAT3 signaling pathway may contribute to cutaneous T-cell lymphomas susceptibility
B Olszewska, J Gleń, M Zabłotna, RJ Nowicki, M Sokołowska-Wojdyło
Archives of Dermatological Research 2020
IL-6 in inflammation, autoimmunity and cancer
T Hirano
International Immunology 2020
A Specific IL6 Polymorphic Genotype Modulates the Risk of Trypanosoma cruzi Parasitemia While IL18, IL17A, and IL1B Variant Profiles and HIV Infection Protect Against Cardiomyopathy in Chagas Disease
AG dos Santos, EH Watanabe, DT Ferreira, J Oliveira, ÉS Nakanishi, CS Oliveira, E Bocchi, CT Novaes, F Cruz, NB Carvalho, PK Sato, EH Yamashiro-Kanashiro, A Pontillo, VL de Freitas, LF Onuchic, MA Shikanai-Yasuda
Frontiers in immunology 2020
Interactions among Interleukin-6, C-Reactive Protein and Interleukin-6 (-174) G/C Polymorphism in the Pathogenesis of Crohn’s Disease and Ulcerative Colitis
B Takač
ACTA CLIN CROAT 2020
Interleukin-6 -174 G/C polymorphism is associated with the risk of basal cell carcinoma in a Chinese Han population
J Wang, Y Chen
Aging 2020
The Multi-Omics Architecture of Juvenile Idiopathic Arthritis
X Hou, H Qu, S Zhang, X Qi, H Hakonarson, Q Xia, J Li
Cells 2020
Interleukin-6-174G/C polymorphism is associated with a decreased risk of type 2 diabetes in patients with chronic hepatitis C virus
CB da Silva, DA Vieira, LF de Melo, AL Chagas, AD Gomes, , R Teixeira, DM de Magalhães Queiroz, GA Rocha, MM Soares, JM Bezerra, LD Silva
World journal of hepatology 2020
Tumor mutation burden associated with miRNA-gene interaction outcome mediates the survival of patients with liver hepatocellular carcinoma.
Yu QJ, Liang YZ, Mei XP, Fang TY
EXCLI journal 2020
Cancer Immunology: A Translational Medicine Context
N Rezaei
2020
How autoinflammation may turn into autoimmune inflammation: Insights from monogenetic and complex IL-1 mediated auto-inflammatory diseases
NM ter Haar, MH Jansen, JF Frenkel, SJ Vastert
Clinical Immunology 2020
The combined frequencies of the IL-6 G-174C and IGFBP3 A-202C polymorphisms among swimmers and runners
S Ben-Zaken, Y Meckel, D Nemet, E Kassem, A Eliakim
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2020
Molecular and Cellular Mechanisms of Arthritis in Children and Adults: New Perspectives on Applied Photobiomodulation
LM Ailioaie, G Litscher
International journal of molecular sciences 2020
IL6 and FAS/FASL gene polymorphisms may be associated with disease progression in HIV‐1‐positive ethnically mixed patients
MM dos Reis, MA Queiroz, BC Silva, AJ Duarte, J Casseb, GA Arganaraz, AC Vallinoto, ER Argañaraz
Journal of Medical Virology 2020
Investigation of the Role of Interleukin 6 in Vitiligo Pathogenesis
M Singh, SD Jadeja, J Vaishnav, MS Mansuri, C Shah, JM Mayatra, A Shah, R Begum
Immunological Investigations 2020
Interleukin Gene Variability and Periodontal Bacteria in Patients with Generalized Aggressive Form of Periodontitis
PB Linhartova, Z Danek, T Deissova, F Hromcik, B Lipovy, D Szaraz, J Janos, A Fassmann, J Bartova, I Drizhal, LI Holla
International journal of molecular sciences 2020
The Perfect Storm: COVID-19 Health Disparities in US Blacks
N Phillips, IW Park, JR Robinson, HP Jones
Journal of Racial and Ethnic Health Disparities 2020
The Association between Interleukin-6 Gene Polymorphisms and Risk of Systemic Lupus Erythematosus: A Meta-analysis with Trial Sequential Analysis
J Liu, MQ Liao, DF Cao, Y Yang, Y Yang, YH Liu, FF Zeng, XH Chen
Immunological Investigations 2020
Genetic polymorphisms in the Interleukins IL1B, IL4, and IL6 are associated with concomitant periodontitis and type 2 diabetes mellitus in Brazilian patients
T Cirelli, R Nepomuceno, AC Rios, SR Orrico, JA Cirelli, LH Theodoro, SP Barros, RM ScarelCaminaga
Journal of Periodontal Research 2020
Meta-analysis and field synopsis of genetic variants associated with the risk and severity of acute pancreatitis
FF van den Berg, MA Kempeneers, HC van Santvoort, AH Zwinderman, Y Issa, MA Boermeester
2020
Cytokine genes multi-locus analysis reveals synergistic influence on genetic susceptibility in Indian SLE – A multifactor-dimensionality reduction approach
V Umare, V Pradhan, S Dadheech, A Rajadhyaksha, K Ghosh, A Nadkarni
Cytokine 2020
Real-Time Monitoring and Detection of Single-Cell Level Cytokine Secretion Using LSPR Technology
C Zhu, , WV Espulgar, S Koyama, A Kumanogoh, M Saito, H Takamatsu, E Tamiya
MICROMACHINES-BASEL 2020
IL6 genetic variants haplotype is associated with susceptibility and disease activity but not with therapy response in patients with inflammatory bowel disease
BP Gonçalves, T Flauzino, CJ Inoue, JC de Paula, TC Galvão, CC de Alcantara, PK Miyazaki, L Rosa, S Westmore, MA Lozovoy, EM Reiche, AN Simão
International Journal of Colorectal Disease 2020
Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database
A Ceschi, R Noseda, K Palin, K Verhamme
Frontiers in pharmacology 2020

Genetic Polymorphisms in Transforming Growth Factor-β, Interferon-γ and Interleukin-6 Genes and Susceptibility to Behcet’s Disease in Saudi Population


FA Okaily, S Alrashidi, M Mustafa, FB Alrashdan
Pharmacogenomics and Personalized Medicine 2020
Risk Factors for Recurrent Colorectal Polyps
Y Hao, Y Wang, M Qi, X He, Y Zhu, J Hong
Gut and Liver 2020
Systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome due to a CASP1 variant causing inflammasome hyperactivation
SE Jørgensen, M Christiansen, C Høst, M Glerup, B Mahler, MM Lausten, HH Gad, R Hartmann, T Herlin, TH Mogensen
Rheumatology 2020
Role of Interleukin-6 in Depressive Disorder
EY Ting, AC Yang, SJ Tsai
International journal of molecular sciences 2020
Association between interleukin gene polymorphisms and multiple myeloma susceptibility
M Shahzad, I Ijaz, S Naqvi, C Yan, F Lin, S Li, C Huang
Molecular and Clinical Oncology 2020
Association of CRP, CD14, Pro-Inflammatory Cytokines and Their Receptors (TNFA, LTA, TNFRSF1A, TNFRSF1B, IL1B, and IL6) Genes with Chronic Obstructive Pulmonary Disease Development
GF Korytina, LZ Akhmadishina, OV Kochetova, YG Aznabaeva, SM Izmailova, SZ Zagidullin, TV Victorova
Russian Journal of Genetics 2020
Impact of IL-17F 7488T/C Functional Polymorphism on Progressive Rheumatoid Arthritis: Novel Insight from the Molecular Dynamic Simulations
H Nisar, U Pasha, MU Mirza, R Abid, K Hanif, HN Kadarmideen, S Sadaf
Immunological Investigations 2020
Interactions Between Diet Quality and Interleukin-6 Genotypes Are Associated With Metabolic and Renal Function Parameters in Mexican Patients With Type 2 Diabetes Mellitus
EF Gómez-García, L Cortés-Sanabria, AM Cueto-Manzano, RS Medina-Zavala, LE Hernández-Ramos, HR Martínez-Ramírez, JC Vásquez-Jiménez, F Mendoza-Carrera
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2020
Epidemic Myalgia Associated with Human Parechovirus Type 3 Infection
M Miyazaki, K Hara, T Takayoshi, T Kawase, Y Nakagawa, T Arai, T Sugimoto, K Nishiyama, G Gonzalez, N Hanaoka, T Fujimoto, Y Yasutomo, K Yokono
Internal Medicine 2020
Association of IL-6 174G/C (rs1800795) and 572C/G (rs1800796) polymorphisms with risk of osteoporosis: a meta-analysis
B Chen, H Li
BMC musculoskeletal disorders 2020
Clinical Management of Il-6 Driven Cytokine Storm Related to COVID-19 in a Patient with Recent Spinal Cord Stimulator Implants: A Case Report
A Papa, MT Dato, P Buonavolonta, E Saracco, AM Salzano, B Casale
Anesthesiology and Pain Medicine 2020
Association of Polymorphisms in Cytokine genes with susceptibility to Precancerous Lesions and Cervical Cancer: A systematic review with meta-analysis
EL de Moura, AC dos Santos, DM da Silva, BB dos Santos, D de Siqueira Figueredo, AW Moura, AF da Silva, IS Tanabe, EL de Lira Tanabe, AB Neto, AC e Silva, CA de Carvalho Fraga, JL de Lima Filho, KF de Farias, EV de Souza
Immunological Investigations 2020
Role of inflammatory and pain genes polymorphisms in temporomandibular disorder and pressure pain sensitivity
LM Fiamengui, BD Furquim, GD la Torre Canales, FF Soares, RL Poluha, CE Repeke, LR Bonjardim, GP Garlet, PC Conti
Archives of Oral Biology 2020
Meta-analysis of association between il-6-174 g/c polymorphism and female infertility related disorders
JJ Benjamin, T Koshy, KM Kumar, KN Maruthy, R Padmavathi
Journal of Reproductive Immunology 2020
The role of IL-6-174 G/C polymorphism and intraocular IL-6 levels in the pathogenesis of ocular diseases: a systematic review and meta-analysis
ZS Ulhaq, GV Soraya, Budu, LR Wulandari
Scientific Reports 2020
IL-1β, IL-6, IL-10, and TNFα Single Nucleotide Polymorphisms in Human Influence the Susceptibility to Alzheimer’s Disease Pathology
MB Leko, MN Perković, N Klepac, DŠ Štrac, F Borovečki, N Pivac, PR Hof, G Šimić
Journal of Alzheimer's disease : JAD 2020
Associations between IL1RAP rs4624606, IL1RL1 rs1041973, IL-6 rs1800795, and HTRA1 rs11200638 gene polymorphisms and development of optic neuritis with or without multiple sclerosis
V Stonys, M Lindžiūtė, A Vilkevičiūtė, G Gedvilaitė, L Kriaučiūnienė, M Banevičius, R Žemaitienė, R Liutkevičienė
Ophthalmic Genetics 2020
Regulation of interleukin 6 by a polymorphic CpG within the frontal cortex in Alzheimer’s disease
X Sawkulycz, S Bradburn, A Robinson, A Payton, N Pendleton, C Murgatroyd
Neurobiology of Aging 2020
Promoter polymorphisms in IL-6 gene influence pro-inflammatory cytokines for the risk of osteoarthritis
M Singh, S Mastana, S Singh, PK Juneja, T Kaur, P Singh
Cytokine 2020
Association of interleukin1β, interleukin1 receptor antagonist, interleukin 6 and angiotensin II receptor type I gene polymorphisms with end stage renal disease: A meta-analysis
D Murugan, G Natarajan, S Natarajan, SB Stephen, S Varghese, Langeswaran, GK Subbaraj
Gene Reports 2020
Genetic polymorphism of the infl ammatory cytokines IL-1β and IL-6 in patients with serologically identifi ed atrophic gastritis
AV Belkovets, SA Kurilovich, VN Maksimov, LV Scherbakova
2020
Association between HER2 and IL-6 genes polymorphisms and clinicopathological characteristics of breast cancer: significant role of genetic variability in specific breast cancer subtype
OE Bouhniz, S Zaied, L Naija, I Bettaieb, K Rahal, M Driss, A Kenani
Clinical and Experimental Medicine 2020
Beyond the HLA polymorphism: A complex pattern of genetic susceptibility to pemphigus
ML Petzl-Erler
Genetics and molecular biology 2020
Pro-inflammatory cytokine response pre-dominates immuno-genetic pathway in development of rheumatoid arthritis
EK Priya, L Srinivas, S Rajesh, K Sasikala, M Banerjee
Molecular Biology Reports 2020
Cytokines and Their Genetic Polymorphisms Related to Periodontal Disease
M Kozak, E Dabrowska-Zamojcin, M Mazurek-Mochol, A Pawlik
Journal of Clinical Medicine 2020
β-Catenin and TCFs/LEF signaling discordantly regulate IL-6 expression in astrocytes
KR Robinson, SD Narasipura, J Wallace, EM Ritz, L Al-Harthi
Cell Communication and Signaling 2020
Gene polymorphisms and expression levels of interleukin-6 and interleukin-10 in lumbar disc disease: a meta-analysis and immunohistochemical study
Y Guan, S Wang, J Wang, D Meng, H Wu, Q Wei, H Jiang
Journal of orthopaedic surgery and research 2020
No Major Effect of Innate Immune Genetics on Acute Kidney Rejection in the First 2 Weeks Post-Transplantation
R Hu, DT Barratt, JK Coller, BC Sallustio, AA Somogyi
Frontiers in pharmacology 2020
Cytokine gene polymorphisms in Pigeon Breeder's Disease expression
Cláudia Freitas, Bruno Lima, Natália Martins, Natália Melo, Patrícia Mota, Hélder Novais-Bastos, Helena Alves, Oksana Sokhatska, Luís Delgado, António Morais
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 2020
Autoinflammatory Pathogenesis and Targeted Therapy for Adult-Onset Still's Disease.
Li S, Zheng S, Tang S, Pan Y, Zhang S, Fang H, Qiao J
Clinical Reviews in Allergy & Immunology 2020
Risk Factors for Recurrent Colorectal Polyps.
Hao Y, Wang Y, Qi M, He X, Zhu Y, Hong J
Gut and Liver 2020
Real-Time Monitoring and Detection of Single-Cell Level Cytokine Secretion Using LSPR Technology.
Zhu C, Luo X, Espulgar WV, Koyama S, Kumanogoh A, Saito M, Takamatsu H, Tamiya E
Micromachines 2020
Association between interleukin gene polymorphisms and multiple myeloma susceptibility.
Shahzad MN, Ijaz I, Naqvi SSZH, Yan C, Lin F, Li S, Huang C
Molecular and Clinical Oncology 2020
Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database.
Ceschi A, Noseda R, Palin K, Verhamme K
Frontiers in pharmacology 2020
Association of IL-6 174G/C (rs1800795) and 572C/G (rs1800796) polymorphisms with risk of osteoporosis: a meta-analysis.
Chen B, Li HZ
BMC musculoskeletal disorders 2020
Interleukin Gene Variability and Periodontal Bacteria in Patients with Generalized Aggressive Form of Periodontitis.
Borilova Linhartova P, Danek Z, Deissova T, Hromcik F, Lipovy B, Szaraz D, Janos J, Fassmann A, Bartova J, Drizhal I, Izakovicova Holla L
International journal of molecular sciences 2020
Effects of the IL6 -174G>C promoter polymorphism and IL-6 serum levels on the progression of cutaneous malignant melanoma.
Vlaykova T, Kurzawski M, Tacheva T, Dimov D, Anastasov A, Vlaykova D, Miteva A, O'donoghue N, Drozdzik M
Oncology Letters 2020
Uncovering Outcome Disparities of β2 Adrenergic Agonists in Blacks: A Systematic Review.
Jerome RN, Pulley JM, Sathe NA, Krishnaswami S, Dickerson AB, Worley KJ, Lima MF, Wilkins CH
Journal of the National Medical Association 2020
Genetic Polymorphisms in Transforming Growth Factor-β, Interferon-γ and Interleukin-6 Genes and Susceptibility to Behcet's Disease in Saudi Population.
Al Okaily F, Alrashidi S, Mustafa M, Alrashdan FB
Pharmacogenomics and Personalized Medicine 2020
Interleukin-6 and Interleukin-10 Gene Polymorphisms in Patients with Chronic Periodontitis and Response to Treatment after 3 Years.
Chatzopoulos GS, Doufexi AE, Zarenti S, Anastasopoulos M, Kouvatsi A
Acta Stomatologica Croatica 2020
Clinical Management of Il-6 Driven Cytokine Storm Related to COVID-19 in a Patient with Recent Spinal Cord Stimulator Implants: A Case Report.
Papa A, Di Dato MT, Buonavolonta P, Saracco E, Salzano AM, Casale B
Anesthesiology and Pain Medicine 2020
Role of Interleukin-6 in Depressive Disorder.
Ting EY, Yang AC, Tsai SJ
International journal of molecular sciences 2020
IL6 genetic variants haplotype is associated with susceptibility and disease activity but not with therapy response in patients with inflammatory bowel disease.
Gonçalves BP, Flauzino T, Inoue CJ, de Paula JCC, Galvão TC, de Alcantara CC, Miyazaki PK, Rosa L, Westmore S, Lozovoy MAB, Reiche EMV, Simão ANC
International Journal of Colorectal Disease 2020
The role of IL-6-174 G/C polymorphism and intraocular IL-6 levels in the pathogenesis of ocular diseases: a systematic review and meta-analysis.
Ulhaq ZS, Soraya GV, Budu, Wulandari LR
Scientific Reports 2020
Single nucleotide polymorphism of transforming growth factor-β1 and interleukin-6 as risk factors for ovarian cancer.
Ahmed AB, Zidi S, Almawi W, Ghazouani E, Mezlini A, Loueslati BY, Stayoussef M
2020
The Perfect Storm: COVID-19 Health Disparities in US Blacks.
Phillips N, Park IW, Robinson JR, Jones HP
Journal of Racial and Ethnic Health Disparities 2020
Risk variants disrupting enhancers of T H 1 and T REG cells in type 1 diabetes
P Gao, Y Uzun, B He, SE Salamati, JK Coffey, E Tsalikian, K Tan
Proceedings of the National Academy of Sciences 2019
Influence of single nucleotide polymorphisms (SNPs) in genetic susceptibility towards periprosthetic osteolysis
S Jagga, AR Sharma, M Bhattacharya, C Chakraborty, SS Lee
Genes & Genomics 2019
Association of Chlamydia trachomatis, C. pneumoniae, and IL-6 and IL-8 Gene Alterations With Heart Diseases
NC Almeida, MA Queiroz, SS Lima, IB Costa, MA Fossa, AC Vallinoto, M de Oliveira Guimarães Ishak, R Ishak
Frontiers in immunology 2019
Racial Differences in Immunological Landscape Modifiers Contributing to Disparity in Prostate Cancer
JK Thomas, H Mir, N Kapur, S Singh
Cancers 2019
STAT3 polymorphisms and IL-6 polymorphism are associated with the risk of basal cell carcinoma in patients from northern Poland
M Sławińska, M Zabłotna, J Gleń, J Lakomy, RJ Nowicki, M Sobjanek
Archives of Dermatological Research 2019
Functions and regulation of T cell-derived interleukin-10
C Neumann, A Scheffold, S Rutz
Seminars in Immunology 2019
The combined polymorphisms of interleukin-6-174GG genotype and interleukin-10 ATA haplotype are associated with a poor quality of life in patients with chronic hepatitis C
DA Vieira, LR da Cunha, CB da Silva, MT Almeida, AD Gomes, , R Teixeira, FS Neves, GA Rocha, FF de Melo, DM de Magalhães Queiroz, LD Silva
Quality of Life Research 2019
Gene polymorphism associated with TNF-α (G308A) IL-6 (C174G) and susceptibility to coronary atherosclerotic heart disease: A meta-analysis
J Yuepeng, X Zhao, Y Zhao, L Li
Medicine 2019
The Role of Polymorphisms in Genes of PI3K/Akt Signaling Pathway on Prostate
W Xu, Z Ni, M Zhang, J Chen, L Zhang, S Wu, C Liang
Journal of Cancer 2019
Auto-Inflammatory Syndromes: Pathophysiology, Diagnosis, and Management
P Efthimiou
2019
Gene polymorphisms in the interleukins gene and the risk of acute pancreatitis: A meta-analysis
X Zhu, C Hou, M Tu, C Shi, L Yin, Y Peng, Q Li, Y Miao
Cytokine 2019
Association of Interleukin-6 -174G/C Polymorphism with the Risk of Diabetic Nephropathy in Type 2 Diabetes: A Meta-analysis
Z Cui, X Lu, K Xiao, Y Chen, H Li
2019
Helicobacter pylori and cytokine gene variants as predictors of premalignant gastric lesions
A Negovan, M Iancu, E Fülöp, C Bănescu
World journal of gastroenterology : WJG 2019
The combined polymorphisms of interleukin-6-174GG genotype and interleukin-10 ATA haplotype are associated with a poor quality of life in patients with chronic hepatitis C
DA Vieira, LR da Cunha, CB da Silva, MT Almeida, AD Gomes, CL de Faria, R Teixeira, FS Neves, GA Rocha, FF de Melo, DM de Magalhães Queiroz, LD Silva
Quality of Life Research 2019
Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overview
Z Heidari, B Moudi, H Mahmoudzadeh-Sagheb
BMC oral health 2019
Bead-type polystyrene/nano-CaCO 3 (PS/nCaCO 3 ) composite: a high-performance adsorbent for the removal of interleukin-6
Y Chai, J Chen, T Wang, J Chen, Y Ma, G Cheng, C Li, Q Zhang, L Ou, W Li
Journal of Materials Chemistry B 2019
Textbook of Autoinflammation
PJ Hashkes, RM Laxer, A Simon
2019
Genetic Polymorphisms in Sepsis and Cardiovascular Disease
T Nakada, W Takahashi, E Nakada, T Shimada, JA Russell, KR Walley
Chest 2019
The association between interleukin-6 gene -174G/C single nucleotide polymorphism and sepsis: an updated meta-analysis with trial sequential analysis
Y Chen, Y Hu, Z Song
BMC Medical Genetics 2019
Polymorphisms of cytokine genes and tuberculosis in two independent studies
S Wu, MG Wang, Y Wang, JQ He
Scientific Reports 2019
Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis
C Konwar, GF Gobbo, J Terry, WP Robinson
BMC Medical Genetics 2019
Molecular Diagnostics in Cancer Patients
KK Shukla, P Sharma, S Misra
2019
Autoinflammatory Pathogenesis and Targeted Therapy for Adult-Onset Still’s Disease
S Li, S Zheng, S Tang, Y Pan, S Zhang, H Fang, J Qiao
Clinical Reviews in Allergy & Immunology 2019
The role of damage-associated molecular pattern for pathogenesis and biomarkers in adult-onset Still’s disease
JY Jung, CH Suh, HA Kim
Expert Review of Molecular Diagnostics 2019
A longitudinal analysis of cytokines in anorexia nervosa
B Dalton, J Leppanen, IC Campbell, R Chung, G Breen, U Schmidt, H Himmerich
Brain, Behavior, and Immunity 2019
Potential Determinants of Gastrointestinal Dysfunction in Autism Spectrum Disorders
AE Shindler, EL Hill-Yardin, S Petrovski, AC Cunningham, N Bishop, AE Franks
Review Journal of Autism and Developmental Disorders 2019
Periodic and Non-Periodic Fevers
R Cimaz
2019
Inflammation-related genes are associated with epigenetic aging in HIV
EE Sundermann, MA Hussain, DJ Moore, S Horvath, DT Lin, MS Kobor, A Levine
Journal of Neurovirology 2019
Impact of interleukin-6 gene polymorphisms and its interaction with obesity on osteoporosis risk in Chinese postmenopausal women
YF Ji, X Jiang, W Li, X Ge
Environmental Health and Preventive Medicine 2019
Association between interleukin-6 gene polymorphisms and febrile seizure risk: A meta-analysis
Q Chen, M Li, X Zhang, X Zhang, R Zhong, W Lin
Medicine 2019
Association Between IL-6 Polymorphisms and Diabetic Nephropathy Risk: A Meta-analysis
B Chen, M Wu, C Zang, Y Li, Z Xu
The American Journal of the Medical Sciences 2019
Interleukin-6 gene polymorphisms and susceptibility to liver diseases: A meta-analysis
X Wang, Z Yan, Q Ye
Medicine 2019
Genetic Basis for the Dominance of Israeli Long-Distance Runners of Ethiopian Origin
S Ben-Zaken, Y Meckel, D Nemet, E Kassem, A Eliakim
Journal of Strength and Conditioning Research 2019
Genetic Association Analyses Highlight IL6 , ALPL , and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis
S Thériault, C Dina, D Messika-Zeitoun, SL Scouarnec, R Capoulade, N Gaudreault, S Rigade, Z Li, F Simonet, M Lamontagne, MA Clavel, BJ Arsenault, AS Boureau, S Lecointe, E Baron, S Bonnaud, M Karakachoff, E Charpentier, I Fellah, JC Roussel, JP Verhoye, C Baufreton, V Probst, R Roussel, R Redon, F Dagenais, P Pibarot, P Mathieu, TL Tourneau, Y Bossé, JJ Schott, B Balkau, P Ducimetière, E Eschwège, F Alhenc-Gelas, A Girault, F Fumeron, M Marre, F Bonnet, A Bonnefond, P Froguel, F Rancière, J Cogneau, C Born, E Caces, M Cailleau, O Lantieri, JG Moreau, F Rakotozafy, J Tichet, S Vol
Circulation. Genomic and precision medicine 2019
Functional polymorphisms within the inflammatory pathway regulate expression of extracellular matrix components in a genetic risk dependent model for anterior cruciate ligament injuries
MA Suijkerbuijk, M Ponzetti, M Rahim, M Posthumus, CK Häger, E Stattin, KG Nilsson, A Teti, DE Meuffels, BJ van der Eerden, M Collins, AV September
Journal of Science and Medicine in Sport 2019
Expression of suppressor of cytokine signaling 3 (SOCS3) and interleukin-6 (-174-G/C) polymorphism in atopic conditions
A Jannat, M Khan, M Shabbir, Y Badshah, L Chatenoud
PloS one 2019
Association between IL-6 polymorphisms and sepsis
P Hu, Y Chen, J Pang, X Chen
Innate immunity 2019
Cytokine Expression Patterns and Single Nucleotide Polymorphisms (SNPs) in Patients with Chronic Borreliosis
Hein, Sander, Giryes, Reinhardt, Hoegel, Schneider
Antibiotics 2019
Association study of single nucleotide polymorphisms in IL-10 and IL-17 genes with the severity of microbial keratitis
NA Carnt, V Cipriani, FJ Stapleton, V Calder, MD Willcox
Contact Lens and Anterior Eye 2019
The Effect of Habitual Fat Intake, IL6 Polymorphism, and Different Diet Strategies on Inflammation in Postmenopausal Women with Central Obesity
A Chmurzynska, A Muzsik, P Krzyżanowska-Jankowska, J Walkowiak, J Bajerska
Nutrients 2019
Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overview.
Heidari Z, Moudi B, Mahmoudzadeh-Sagheb H
BMC oral health 2019
The association between interleukin-6 gene -174G/C single nucleotide polymorphism and sepsis: an updated meta-analysis with trial sequential analysis.
Chen Y, Hu Y, Song Z
BMC Medical Genetics 2019
Polymorphisms of cytokine genes and tuberculosis in two independent studies.
Wu S, Wang MG, Wang Y, He JQ
Scientific Reports 2019
Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis.
Konwar C, Del Gobbo GF, Terry J, Robinson WP
BMC Medical Genetics 2019
Expression of suppressor of cytokine signaling 3 (SOCS3) and interleukin-6 (-174-G/C) polymorphism in atopic conditions.
Jannat A, Khan M, Shabbir M, Badshah Y
PloS one 2019
The Effect of Habitual Fat Intake, IL6 Polymorphism, and Different Diet Strategies on Inflammation in Postmenopausal Women with Central Obesity.
Chmurzynska A, Muzsik A, Krzyżanowska-Jankowska P, Walkowiak J, Bajerska J
Nutrients 2019
Impact of interleukin-6 gene polymorphisms and its interaction with obesity on osteoporosis risk in Chinese postmenopausal women.
Ji YF, Jiang X, Li W, Ge X
Environmental Health and Preventive Medicine 2019
Cytokine Expression Patterns and Single Nucleotide Polymorphisms (SNPs) in Patients with Chronic Borreliosis.
Hein TM, Sander P, Giryes A, Reinhardt JO, Hoegel J, Schneider EM
2019
Association between IL-6 polymorphisms and sepsis.
Hu P, Chen Y, Pang J, Chen X
Innate immunity 2019
Interleukin-6 gene polymorphisms and susceptibility to liver diseases: A meta-analysis.
Wang X, Yan Z, Ye Q
Medicine 2019
Association between Hepatitis C Virus Viremia and the rs12979860, rs2228145 and rs1800795 SNP (CT/AC/GG) Genotype in Saudi Kidney Transplant Recipients.
Alkharsah KR, Alzahrani AJ, Obeid OE, Aljindan RY, Guella A, Al-Ali AK, Al-Turaifi HR, Sallam TA
2019
Association between interleukin-6 gene polymorphisms and febrile seizure risk: A meta-analysis.
Chen Q, Li M, Zhang X, Zhang X, Zhong R, Lin W
Medicine 2019
Epidemic Myalgia Associated with Human Parechovirus Type 3 Infection.
Miyazaki M, Hara K, Takayoshi T, Kawase T, Nakagawa Y, Arai T, Sugimoto T, Nishiyama K, Gonzalez G, Hanaoka N, Fujimoto T, Yasutomo Y, Yokono K
Internal Medicine 2019
Meta-analysis and field synopsis of genetic variants associated with the risk and severity of acute pancreatitis.
van den Berg FF, Kempeneers MA, van Santvoort HC, Zwinderman AH, Issa Y, Boermeester MA
2019
Streptococcal pharyngitis and rheumatic heart disease: the superantigen hypothesis revisited
JR Hurst, KJ Kasper, AN Sule, JK McCormick
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2018
The Two-Faced Cytokine IL-6 in Host Defense and Diseases
M Narazaki, T Kishimoto
International journal of molecular sciences 2018
Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines
IM Rea, DS Gibson, V McGilligan, SE McNerlan, HD Alexander, OA Ross
Frontiers in immunology 2018
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
DE Johnson, RA O'Keefe, JR Grandis
Nature Reviews Clinical Oncology 2018
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
L Ferrucci, E Fabbri
Nature Reviews Cardiology 2018
Genetic Polymorphisms Associated with Spontaneous Intracerebral Hemorrhage
YC Chen, KH Chang, CM Chen
International journal of molecular sciences 2018
Interleukin 6 and 10 Serum Levels and Genetic Polymorphisms in Children with Down Syndrome
MF Mattos, PM Biselli-Chicote, JM Biselli, TL da Silva Assembleia, EM Goloni-Bertollo, ÉC Pavarino
Mediators of Inflammation 2018
Inflammatory Profiles of the Interleukin Family and Network in Cerebral Hemorrhage
L Ye, L Gao, H Cheng
Cellular and Molecular Neurobiology 2018
IL-27: a double agent in the IL-6 family: IL-27 and IL-6 in inflammatory arthritis
GW Jones, DG Hill, A Cardus, SA Jones
Clinical & Experimental Immunology 2018
Interleukin-6 significantly improves predictive value of systemic inflammatory response syndrome for predicting severe acute pancreatitis
S Jain, S Midha, SJ Mahapatra, S Gupta, MK Sharma, B Nayak, TG Jacob, Shalimar, PK Garg
Pancreatology 2018
A novel predictive approach for GVHD after allogeneic SCT based on clinical variables and cytokine gene polymorphisms
C Martínez-Laperche, E Buces, MC Aguilera-Morillo, A Picornell, M González-Rivera, R Lillo, N Santos, B Martín-Antonio, V Guillem, JB Nieto, M González, R de la Cámara, S Brunet, A Jiménez-Velasco, I Espigado, C Vallejo, A Sampol, JM Bellón, D Serrano, M Kwon, J Gayoso, P Balsalobre, Á Urbano-Izpizua, C Solano, D Gallardo, JL Díez-Martín, J Romo, I Buño
Blood Advances 2018
Novel Anti-arthritic Mechanisms of Polydatin in Complete Freund's Adjuvant-Induced Arthritis in Rats: Involvement of IL-6, STAT-3, IL-17, and NF-кB.
Kamel KM, Gad AM, Mansour SM, Safar MM, Fawzy HM
Inflammation 2018
Association between the -174 C/G polymorphism in the interleukin-6 (IL-6) gene and gastrointestinal involvement in patients with systemic sclerosis
A Zekovic, M Vreca, V Spasovski, M Andjelkovic, S Pavlovic, N Damjanov
Clinical Rheumatology 2018
− 174 G>C IL-6 polymorphism and primary iron overload in male patients
WF Tetzlaff, T Meroño, EE Botta, ME Martín, PB Sorroche, LE Boero, M Castro, GD Frechtel, J Rey, J Daruich, GE Cerrone, F Brites
Annals of Hematology 2018
Control of Listeria monocytogenes infection requires classical IL-6 signaling in myeloid cells
K Lücke, I Yan, S Krohn, A Volmari, S Klinge, J Schmid, V Schumacher, OM Steinmetz, S Rose-John, HW Mittrücker, ME Rottenberg
PloS one 2018
Adult-Onset Still’s Disease: Molecular Pathophysiology and Therapeutic Advances
P Sfriso, S Bindoli, P Galozzi
Drugs 2018
Genetic Polymorphisms of IL1B, IL6, and TNF α in a Chinese Han Population with Pulmonary Tuberculosis
S Wu, Y Wang, M Zhang, SS Shrestha, M Wang, JQ He
BioMed Research International 2018
Handbook of Immunosenescence: Basic Understanding and Clinical Implications
T Fulop, C Franceschi, K Hirokawa, G Pawelec
Handbook of Immunosenescence 2018
Methylation Status of Interleukin-6 Gene Promoter in Patients with Behçet's Disease
S Alipour, E Sakhinia, A Khabbazi, N Samadi, Z Babaloo, M Azad, S Abolhasani, J Farhadi, G Jadideslam, N Roshanravan, M Nouri
Reumatología Clínica 2018
Interleukin 6 gene polymorphism is associated with protein serum level and disease activity in Polish patients with rheumatoid arthritis
J Wielińska, M Dratwa, J Świerkot, L Korman, M Iwaszko, B Wysoczańska, K Bogunia-Kubik
HLA 2018
Lack of association between single-nucleotide polymorphisms of pro- and anti-inflammatory cytokines and HTLV-1-associated myelopathy / tropical spastic paraparesis development in patients from Rio de Janeiro, Brazil
D Schor, LC Porto, EH Roma, M de Souza Borges Quintana, GM Fabricio-Silva, MG Bonecini-Almeida, AQ Araújo, MJ Andrada-Serpa
BMC Infectious Diseases 2018
Allelic Combinations of Immune Response Genes and Risk of Development of Myocardial Infarction
RI Sadikova, TR Nasibullin, YR Timasheva, IA Tuktarova, VV Erdman, MI Shein, IE Nikolaeva, OE Mustafina
Russian Journal of Genetics 2018
No association of IL2, IL4, IL6, TNF , and IFNG gene polymorphisms was found with Taenia solium human infection or neurocysticercosis severity in a family-based study
A Fleury, C Alaez, A Dessein, M Rosetti, B Saenz, M Hernández, RJ Bobes, R Ramírez-Aquino, E Sciutto, C Gorodezky, G Fragoso
Human Immunology 2018
Inflammatory and apoptotic signalling pathways and concussion severity: a genetic association study
SM Fie, S Abrahams, J Patricios, J Suter, M Posthumus, AV September
Journal of Sports Sciences 2018
IL1RN Variation Influences Both Disease Susceptibility and Response to Recombinant Human Interleukin-1 Receptor Antagonist Therapy in Systemic Juvenile Idiopathic Arthritis
VL Arthur, E Shuldiner, EF Remmers, A Hinks, AA Grom, D Foell, A Martini, M Gattorno, S Özen, S Prahalad, AS Zeft, JF Bohnsack, NT Ilowite, ED Mellins, R Russo, C Len, S Oliveira, RS Yeung, AM Rosenberg, LR Wedderburn, J Anton, JP Haas, A Rösen-Wolff, K Minden, AM Szymanski, W Thomson, DL Kastner, P Woo, MJ Ombrello
Arthritis & Rheumatology 2018
Association between rs1800795 polymorphism in the interleukin-6 gene and the risk of polycystic ovary syndrome: A meta-analysis
L Chen, Z Zhang, J Huang, M Jin
Medicine 2018
Influence of cytokine gene polymorphism on the risk of rheumatic heart disease – A meta-analysis
M Bhatt, S Kumar, MH Siddiqui, N Garg, B Mittal
Immunology Letters 2018
The association between interleukin polymorphism and recurrent aphthous stomatitis: A meta-analysis
D Wu, J Xin, J Liu, P Zhou
Archives of Oral Biology 2018
Polymorphic Variants of Immune Response Genes as a Risk Factor for the Development of Primary Progressive Multiple Sclerosis
EV Popova, IS Kiselev, AN Boiko, SA Sivertseva, NA Malkova, DS Korobko, NN Spirin, DS Kasatkin, AV Karaeva, EL Turova, NN Spirina, LI Volkova, NM Baulina, VV Bashinskaya, OG Kulakova, OO Favorova
Neuroscience and Behavioral Physiology 2018
Impact of interleukin 6 promoter polymorphisms (−174 G > C, −572 G > C and −597 G > A) on plasma IL-6 levels and their influence on the development of DVT: a study from India
A Sharma, K Singh, A Biswas, R Ranjan, K Kishor, H Pandey, R Kumar, M Mahapatra, J Oldenburg, R Saxena
Hematology 2018
From traditional biochemical signals to molecular markers for detection of sepsis after burn injuries
B Muñoz, R Suárez-Sánchez, O Hernández-Hernández, R Franco-Cendejas, H Cortés, JJ Magaña
Burns : journal of the International Society for Burn Injuries 2018
A pilot study of single nucleotide polymorphisms in the interleukin-6 receptor and their effects on pre- and post-transplant serum mediator level and outcome after allogeneic stem cell transplantation: SNPs in the IL-6R and allotransplantation
TH Tvedt, R Hovland, G Tsykunova, AB Ahmed, T Gedde-Dahl, Ø Bruserud
Clinical & Experimental Immunology 2018
PPARG2 Pro12Ala polymorphism influences body composition changes in severely obese patients consuming extra virgin olive oil: a randomized clinical trial
AP Rodrigues, LP Rosa, EA Silveira
Nutrition & Metabolism 2018
Association of the Interleukin-6 rs1800795 Polymorphism with Type 2 Diabetes Mellitus in the Population of the Island of Crete, Greece
MN Plataki, MI Zervou, G Samonis, V Daraki, GN Goulielmos, DP Kofteridis
Genetic Testing and Molecular Biomarkers 2018
The association between periodontitis and interleukin-6 genetic polymorphism -174 G/C: A meta-analysis
B Zhao, R Li
Archives of Oral Biology 2018
Novel Anti-arthritic Mechanisms of Polydatin in Complete Freund’s Adjuvant-Induced Arthritis in Rats: Involvement of IL-6, STAT-3, IL-17, and NF-кB
KM Kamel, AM Gad, SM Mansour, MM Safar, HM Fawzy
Inflammation 2018
Genetics Factors in Major Depression Disease
M Shadrina, EA Bondarenko, PA Slominsky
Frontiers in Psychiatry 2018
Genetics and genomics in postoperative pain and analgesia:
V Palada, MA Kaunisto, E Kalso
Current Opinion in Anaesthesiology 2018
Genetic Variants and Hamstring Injury in Soccer: An Association and Validation Study
J Larruskain, DA Celorrio, I Barrio, A Odriozola, SM Gil, JR Fernandez-Lopez, R Nozal, I Ortuzar, JA Lekue, JM Aznar
Medicine and Science in Sports and Exercise 2018
Association of IL-6 -174G>C (rs1800795) polymorphism with cervical cancer susceptibility
HX Duan, YY Chen, JZ Shi, NN Ren, XJ Li
Bioscience Reports 2018
Effects of increasing ratios of dietary omega-6/omega-3 fatty acids on human monocyte immunomodulation linked with atherosclerosis
AA Alshatwi, P Subash-Babu
Journal of Functional Foods 2018
Serum Interleukin-6 Level and the rs1800795 Polymorphism in its Gene Associated with Neuroblastoma Risk in Chinese Children:
Q Zhao, M Jin, DW Zhang, W Zhao, , ZX Yue, C Duan, C Huang, XL Ma
Chinese Medical Journal 2018
Significant association of IL-6-572G/C, IL-6-597G/A, and IL-6-174G/C polymorphisms and susceptibility to lumbar degenerative disease: A meta-analysis
S Gao, T Xu, C Xun, W Liang, R Cao, C Mao, W Sheng
Clinical Neurology and Neurosurgery 2018
Influence of -174G/C IL-6 gene polymorphism on the susceptibility to rheumatoid arthritis in children and adults in the Republic Of Belarus
HA Yatskiu, DV Balshakova, AM Tchitchko, VE Yagur, AV Sukalo, RI Goncharova
2018
Association between Genes for Inflammatory Factors and Neuroticism, Anxiety, and Depression in Men with Ischemic Heart Disease
VE Golimbet, BA Volel, GI Korovaitseva, SV Kasparov, NV Kondratev, FY Kopylov
Neuroscience and Behavioral Physiology 2018
Cardiovascular Disease: Diet, Nutrition and Emerging Risk Factors
S Stanner, S Coe, KN Frayn
2018
Frailty as an Outcome Predictor After Ankle Fractures: Where Are We Now?
M Mediouni, DR Schlatterer
Geriatric Orthopaedic Surgery & Rehabilitation 2018
Association of Interleukin-4 (-590 C/T) and Interleukin-6 (-174 G/C) Polymorphism in Pathogenesis and Prognosis of Hepatitis C Virus Infection
Y Badshah, N Arshad, M Khan, A Jannat, H Hayat
Journal of Interferon & Cytokine Research 2018
Analysis of association of -174G/C interleukin 6 polymorphism and therapeutic response to methotrexate in rheumatoid arthritis
A Joksimović, C Khouri, B Jekić
2018
Interleukin-6 in juvenile idiopathic arthritis
S Akioka
Modern Rheumatology 2018
A pilot study of single nucleotide polymorphisms in the interleukin-6 receptor and their effects on pre- and post-transplant serum mediator level and outcome after allogeneic stem cell transplantation.
Tvedt THA, Hovland R, Tsykunova G, Ahmed AB, Gedde-Dahl T, Bruserud Ø
Clinical & Experimental Immunology 2018
IL1RN Variation Influences Both Disease Susceptibility and Response to Recombinant Human Interleukin-1 Receptor Antagonist Therapy in Systemic Juvenile Idiopathic Arthritis.
Arthur VL, Shuldiner E, Remmers EF, Hinks A, Grom AA, Foell D, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Ilowite NT, Mellins ED, Russo R, Len C, Oliveira S, Yeung RSM, Rosenberg AM, Wedderburn LR, Anton J, Haas JP, Rösen-Wolff A, Minden K, Szymanski AM, Thomson W, Kastner DL, Woo P, Ombrello MJ
Arthritis & Rheumatism 2018
Association between rs1800795 polymorphism in the interleukin-6 gene and the risk of polycystic ovary syndrome: A meta-analysis.
Chen L, Zhang Z, Huang J, Jin M
Medicine 2018
PPARG2 Pro12Ala polymorphism influences body composition changes in severely obese patients consuming extra virgin olive oil: a randomized clinical trial.
Rodrigues APS, Rosa LPS, Silveira EA
Nutrition & Metabolism 2018
Genetics Factors in Major Depression Disease.
Shadrina M, Bondarenko EA, Slominsky PA
Frontiers in Psychiatry 2018
Polymorphism of IFN-γ +874T/A associated with production of IFN-γ affects human papillomavirus susceptibility in rural women from Luohe, Henan, China.
Zhang QW, Song JY, Yu JH, Sun MZ, Tang SY, Yang SZ, Cao LJ, Wang HF, Cui LN, Fu XH
OncoTargets and therapy 2018
Association of IL-6 -174G>C (rs1800795) polymorphism with cervical cancer susceptibility.
Duan HX, Chen YY, Shi JZ, Ren NN, Li XJ
Bioscience Reports 2018
The relationship between 174 G/C and -572 G/C of IL-6 gene polymorphisms and susceptibility of celiac disease in the Iranian population.
Barartabar Z, Nikzamir A, Sirati-Sabet M, Aghamohammadi E, Chaleshi V, Rostami Nejad M, Asadzadeh-Aghdaei H, Reza Zali M
2018
Interleukin-6 gene -572G/C polymorphism and prostate cancer risk.
Wang Y, Chen X, Chen Y
African health sciences 2018
Association between polymorphism of tumor necrosis factor alpha (tnfα) in the region -308 g/a with tinnitus in the elderly with a history of occupational noise exposure.
Marchiori LLM, Dias ACM, Gonçalvez AS, Poly-Frederico RC, Doi MY
Noise & health 2018
Interleukin-6 in Allogeneic Stem Cell Transplantation: Its Possible Importance for Immunoregulation and As a Therapeutic Target
TH Tvedt, E Ersvaer, AA Tveita, Ø Bruserud
Frontiers in immunology 2017
Polymorphisms in inflammation-related genes and the risk of primary varicose veins in ethnic Russians
A Shadrina, E Voronina, M Smetanina, Y Tsepilov, K Sevostianova, A Shevela, E Seliverstov, E Zakharova, E Ilyukhin, A Kirienko, I Zolotukhin, M Filipenko
Immunologic Research 2017
Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators
HN Nguyen, EH Noss, F Mizoguchi, C Huppertz, KS Wei, GF Watts, MB Brenner
Immunity 2017
Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology
CJ Pyle, FI Uwadiae, DP Swieboda, JA Harker, CB Lopez
PLoS pathogens 2017
Interleukin-6 Genetic Variation and Susceptibility to Gastric Cancer in an Iranian Population
Marzieh Attar, Maryam Mansoori, Majid Shahbazi
Asian Pacific Journal of Cancer Prevention 2017
Kelley and Firestein's Textbook of Rheumatology
PE di Cesare, DR Haudenschild, J Samuels, SB Abramson
Kelley and Firestein's Textbook of Rheumatology 2017
IL-6 rs1800795 polymorphism is associated with septic shock-related death in patients who underwent major surgery: a preliminary retrospective study
MA Jiménez-Sousa, LM Medrano, P Liu, A Fernández-Rodríguez, R Almansa, E Gomez-Sanchez, A Ortega, M Heredia-Rodríguez, E Gómez-Pesquera, E Tamayo, S Resino
Annals of Intensive Care 2017
Genetic predictors of long-term graft function in kidney and pancreas transplant patients
CE Duff, MJ Simmonds
Briefings in Functional Genomics 2017
Influence of IL1B , IL6 and IL10 gene variants and plasma fatty acid interaction on metabolic syndrome risk in a cross-sectional population-based study
MM Norde, E Oki, AA Carioca, NR Damasceno, RM Fisberg, DM Marchioni, MM Rogero
Clinical Nutrition 2017
The Relevance of Coding Gene Polymorphysms of Cytokines and Cellular Receptors in Sepsis
AM Georgescu, BL Grigorescu, IR Chirteș, AA Vitin, RȘ Fodor
The Journal of Critical Care Medicine 2017
Interleukin-6 -572C/G polymorphism is associated with serum interleukin-6 levels and risk of idiopathic pulmonary arterial hypertension
M Fang, Y Huang, Y Zhang, Z Ning, L Zhu, X Li
Journal of the American Society of Hypertension 2017
A 21-Month-Old Male With Refusal to Walk, Rash, and Weight Loss: Clinicopathologic Conference
T Reese, L Villegas, J Wood, A Gotte
Arthritis Care & Research 2017
Association of SNPs from IL1A , IL1B , and IL6 Genes with Human Cytomegalovirus Infection Among Pregnant Women
WI Wujcicka, JS Wilczyński, DE Nowakowska
Viral Immunology 2017
Morbus Still im Kindes- und Erwachsenenalter
CM Hedrich, C Günther, M Aringer
Der Hautarzt 2017
Biomedical Risk Factors of Achilles Tendinopathy in Physically Active People: a Systematic Review
M Kozlovskaia, N Vlahovich, KJ Ashton, DC Hughes
Sports Medicine - Open 2017
IL-6 variant is associated with metastasis in breast cancer patients
CO Abana, BS Bingham, JH Cho, AJ Graves, T Koyama, RT Pilarski, AB Chakravarthy, F Xia, WB Coleman
PloS one 2017
Morbus Still im Kindes- und Erwachsenenalter
CM Hedrich, C Günther, M Aringer
Zeitschrift für Rheumatologie 2017
Study of IL4-590C/T and IL6-174G/C Gene Polymorphisms in Type 2 Diabetic Patients With Chronic Kidney Disease in North Indian Population: G ENE P OLYMORPHISM IN D IABETIC P ATIENTS
K Neelofar, J Ahmad, A Ahmad, K Alam
Journal of Cellular Biochemistry 2017
Effect of maternal and neonatal interleukin-6 − 174 G/C polymorphism on preterm birth and neonatal morbidity
NM Karakaş, AN Ecevit, Y Yalçın, B Özdemir, H Verdi, MA Tekindal, NY Özbek, A Tarcan, FB Ataç, A Haberal
Journal of Maternal-Fetal and Neonatal Medicine 2017
Interleukin 6 gene polymorphism in patients with degenerative lumbar scoliosis: a cohort study
JS Lee, JK Shin, TS Goh
European Spine Journal 2017
Association of inflammatory genes with neuroticism, anxiety and depression in male patients with coronary heart disease
VE Golimbet, BA Volel, GI Korovaitseva, SV Kasparov, NV Kondratiev, FY Kopylov
ZH NEVROL PSIKHIATR 2017
The profile of selected single nucleotide polymorphisms in patients with hypertension and heart failure with preserved and mid-range ejection fraction
A Bielecka-Dabrowa, A Sakowicz, T Pietrucha, M Misztal, P Chruściel, J Rysz, M Banach
Scientific Reports 2017
Increased Prevalence of the IL-6 -174C Genetic Polymorphism in Long Distance Swimmers
S Ben-Zaken, Y Meckel, D Nemet, E Kassem, A Eliakim
Journal of Human Kinetics 2017
IL-6 and IL-10 gene polymorphisms in patients with aggressive periodontitis: effects on GCF, serum and clinic parameters
EP GORGUN, H TOKER, EM KORKMAZ, O POYRAZ
Brazilian Oral Research 2017
The role and therapeutic targeting of IL-6 in rheumatoid arthritis
M Narazaki, T Tanaka, T Kishimoto
Expert Review of Clinical Immunology 2017
Association of IL - 6 -174 G>C polymorphism with the risk of SLE among south Indians: evidence from case–control study and meta-analysis
SK Katkam, L Rajasekhar, K Kumaraswami, VK Kutala
Lupus 2017
Influence of the IL6 − 147C/G polymorphism on clinical characteristics of chronic hepatitis C in Brazilian patients
AA Maya, CF da Alves, CG Marangon, K Frizon, RP Gorziza, VR Lunge, D Simon
Gene Reports 2017
Polymorphic variants of the immune response genes as risk factors for primary progressive multiple sclerosis
EV Popova, IS Kiselev, AN Boyko, SA Sivertseva, NA Malkova, DS Korobko, NN Spirin, DS Kasatkin, AV Karaeva, EL Turova, NN Spirina, LI Volkova, NM Baulina, VV Bashinskaya, OG Kulakova, OO Favorova
ZH NEVROL PSIKHIATR 2017
Association study of interleukin-1 family, interleukin-6, and its receptor gene polymorphisms in patients with recurrent aphthous stomatitis
LI Holla, S Valova, PB Linhartova, J Bartova, J Petanova, P Kuklinek, A Fassmann
Journal of Oral Pathology & Medicine 2017
Influence of TNF and IL6 gene polymorphisms on the severity of cytopenias in Argentine patients with myelodysplastic syndromes
Y Bestach, VP Nagore, MG Flores, J González, J Arbelbide, N Watman, Y Sieza, I Larripa, C Belli
Annals of Hematology 2017
Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression
J Ryan, L Pilkington, K Neuhaus, K Ritchie, ML Ancelin, R Saffery
BMC psychiatry 2017
Polymorphisms in immune-inflammatory response genes and the risk of deficit schizophrenia
M Mak, B Misiak, D Frydecka, J Pełka-Wysiecka, J Kucharska-Mazur, A Samochowiec, P Bieńkowski, E Pawlak-Adamska, L Karabon, E Szmida, P Skiba, K Kotowicz, P Piotrowski, JA Beszłej, J Samochowiec
Schizophrenia Research 2017
Impact of cytokine genetic polymorphisms on the risk of renal parenchymal infection in children
A Hussein, E Askar, A Badawy, K Saad, A Zahran, AA Elderwy
Journal of Pediatric Urology 2017
Update on the management of systemic juvenile idiopathic arthritis and role of IL-1 and IL-6 inhibition
S Grevich, S Shenoi
Adolescent health, medicine and therapeutics 2017
Genetic association of pro-inflammatory cytokine gene polymorphisms with coronary artery disease (CAD) in a North Indian population
S Mastana, S Prakash, EC Akam, M Kirby, MR Lindley, N Sinha, S Agrawal
Gene 2017
Interleukin-6-174G>C gene promoter polymorphism and prognosis in patients with cancer
K Zhai, Y Yang, ZG Gao, J Ding
Oncotarget 2017
Genetic variants in gastric cancer: Risks and clinical implications
CO Gigek, DQ Calcagno, LT Rasmussen, LC Santos, MF Leal, F Wisnieski, RR Burbano, LG Lourenço, GJ Lopes-Filho, MA Smith
Experimental and Molecular Pathology 2017
Regulation of Inflammatory Signaling in Health and Disease
D Xu
Regulation of Inflammatory Signaling in Health and Disease 2017
Pathogenesis of Periodontal Diseases
N Bostanci, GN Belibasakis
Pathogenesis of Periodontal Diseases 2017
Role of TLRs and IL-6 in the outcome of chronic hepatitis C treatment in Tunisian population
I Sghaier, L Mouelhi, E Ghazoueni, E Brochot, WY Almawi, B Yacoubi-Loueslati
Cytokine 2017
Multiple sclerosis genetics: Results from meta-analyses of candidate-gene association studies
K Tizaoui
Cytokine 2017
Handbook of Immunosenescence
T Fulop, C Franceschi, K Hirokawa, G Pawelec
Handbook of Immunosenescence 2017
Genetic variants and acute kidney injury: A review of the literature
DB Larach, MC Engoren, EM Schmidt, M Heung
Journal of Critical Care 2017
Association of cytokine gene polymorphisms with bronchopulmonary dysplasia in Han Chinese newborns
H Chen, W Zheng
Pediatric Pulmonology 2017
Estrogen Metabolism-Associated CYP2D6 and IL6-174G/C Polymorphisms in Schistosoma haematobium Infection
R Cardoso, P Lacerda, P Costa, A Machado, A Carvalho, A Bordalo, R Fernandes, R Soares, J Richter, H Alves, M Botelho
International journal of molecular sciences 2017
Noncoding RNAs: Master Regulators of Inflammatory Signaling
CL Chew, SA Conos, B Unal, V Tergaonkar
Trends in Molecular Medicine 2017
Association of IL-6-174 G/C and IL10-1082 G/A polymorphisms with recurrent aphthous stomatitis risk: A meta-analysis
S Yang, B Zhang, Q Shi, J Liu, J Xu, N Huo
Medicine 2017
Genetic polymorphisms associated with the risk of concussion in 1056 college athletes: a multicentre prospective cohort study
TR Terrell, R Abramson, JT Barth, E Bennett, RC Cantu, R Sloane, DT Laskowitz, DM Erlanger, D McKeag, G Nichols, V Valentine, L Galloway
British journal of sports medicine 2017
Analysis of IL-6, IL-10 and NF-κB Gene Polymorphisms in Aggressive and Chronic Periodontitis
H Toker, EP Görgün, EM Korkmaz
CENT EUR J PUBL HEAL 2017
The association between interleukin 6 −174 G/C gene polymorphism and the risk of osteoporosis: A meta-analysis
JK Fajar, A Azharuddin
Journal of Taibah University Medical Sciences 2017
Interleukin 6 gene polymorphism in patients with degenerative lumbar scoliosis: a cohort study.
Lee JS, Shin JK, Goh TS
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2017
Estrogen Metabolism-Associated CYP2D6 and IL6-174G/C Polymorphisms in Schistosoma haematobium Infection.
Cardoso R, Lacerda PC, Costa PP, Machado A, Carvalho A, Bordalo A, Fernandes R, Soares R, Richter J, Alves H, Botelho MC
International journal of molecular sciences 2017
The Relevance of Coding Gene Polymorphysms of Cytokines and Cellular Receptors in Sepsis.
Georgescu AM, Grigorescu BL, Chirteș IR, Vitin AA, Fodor RȘ
2017
Association of IL-6-174 G/C and IL10-1082 G/A polymorphisms with recurrent aphthous stomatitis risk: A meta-analysis.
Yang S, Zhang B, Shi Q, Liu J, Xu J, Huo N
Medicine 2017
Association of IL-6 C-572G Gene Polymorphism with Anti-E Production.
Lin JS, Lee LH, Liu HM, Chen YJ, Chiou TJ
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie 2017
Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
J White, G Smythe
2016
Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
J White, G Smythe
2016
Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
J White, G Smythe
2016
Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
J White, G Smythe
2016
Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
J White, G Smythe
2016
Aging, inflammation, immunity and periodontal disease
JL Ebersole, CL Graves, OA Gonzalez, D Dawson, LA Morford, PE Huja, JK Hartsfield, SS Huja, S Pandruvada, SM Wallet
Periodontology 2000 2016
Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing
P Baumert, MJ Lake, CE Stewart, B Drust, RM Erskine
European Journal of Applied Physiology 2016
Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis
X Dong, A Cheng, Z Zou, YS Yang, RM Sumpter, CL Huang, G Bhagat, HW Virgin, SA Lira, B Levine
Proceedings of the National Academy of Sciences 2016
IL-6 blockers in systemic onset juvenile idiopathic arthritis
P Barone, R Pignataro, MT Garozzo, S Leonardi
Immunotherapy 2016
Inflammatory Cytokines and Alzheimer’s Disease: A Review from the Perspective of Genetic Polymorphisms
F Su, F Bai, Z Zhang
Neuroscience Bulletin 2016
Is the IL-6 -174G/C Gene Polymorphism Related to the Disease Severity Score in Turkish Children with Familial Mediterranean Fever?
S Özer, R Yilmaz, E Sonmezgoz, Ş Ünuvar, Ö Ates
Biochemical Genetics 2016
Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome
J Yan, G JM, MC PA
Journal of Neuroimmunology 2016
Caspase-1 als Regulator der Autoinflammation bei rheumatischen Erkrankungen
S Winkler, CM Hedrich, A Rösen-Wolff
Zeitschrift für Rheumatologie 2016
Shaping the spectrum — From autoinflammation to autoimmunity
CM Hedrich
Clinical Immunology 2016
Textbook of Pediatric Rheumatology
E Silverman, J Buyon, E Jaeggi
Textbook of Pediatric Rheumatology 2016
Tocilizumab for treating juvenile idiopathic arthritis
JL Turnier, HI Brunner
Expert Opinion on Biological Therapy 2016
Interleukin 6 (IL-6) and IL-10 Promoter Region Polymorphisms Are Associated with Risk of Lumbar Disc Herniation in a Northern Chinese Han Population
X Huang, F Chen, J Zhao, D Wang, S Jing, H Li, C Meng
Genetic Testing and Molecular Biomarkers 2016
Interventions for age-related diseases: shifting the paradigm
I Figueira, A Fernandes, A Mladenovic, A Lopez-Contreras, CM Henriques, C Selman, E Ferreiro, ES Gonos, JL Trejo, J Misra, LJ Rasmussen, S Xapelli, T Ellam, I Bellantuono
Mechanisms of Ageing and Development 2016
The Innate Immune Response to Non-Infectious Stressors
S González, C López-Larrea, A López-Soto
The Innate Immune Response to Non-Infectious Stressors 2016
Pediatric Rheumatology
S Sawhney, A Aggarwal
Pediatric Rheumatology 2016
Regulation of Cytokine Gene Expression in Immunity and Diseases
X Ma
Regulation of Cytokine Gene Expression in Immunity and Diseases 2016
Meta-analysis of the Correlation Between Interleukin-6 Promoter Polymorphism -174G/C and Interferon Regulatory Factor 4 rs12203592 Polymorphism With Skin Cancer Susceptibility:
M Wu, Y Cao, Y Liu, L Ma, X Yang
American Journal of Therapeutics 2016
Hall of Fame among Pro-inflammatory Cytokines: Interleukin-6 Gene and Its Transcriptional Regulation Mechanisms
Y Luo, SG Zheng
Frontiers in immunology 2016
Mitochondrial and oxidative stress genes are differentially expressed in neutrophils of sJIA patients treated with tocilizumab: a pilot microarray study
E Omoyinmi, R Hamaoui, A Bryant, MC Jiang, T Athigapanich, D Eleftheriou, M Hubank, P Brogan, P Woo
Pediatric Rheumatology 2016
Single Nucleotide Polymorphisms in IL17A and IL6 Are Associated with Decreased Risk for Pulmonary Tuberculosis in Southern Brazilian Population
M Milano, MO Moraes, R Rodenbusch, CX Carvalho, M Delcroix, G Mousquer, LL da Costa, G Unis, ER Costa, ML Rossetti, S Subbian
PloS one 2016
Association between Interleukin-6 Promoter Polymorphism (-174 G/C), Serum Interleukin-6 Levels and Mortality in Severe Septic Patients
L Lorente, M Martín, A Pérez-Cejas, Y Barrios, J Solé-Violán, J Ferreres, L Labarta, C Díaz, A Jiménez
International journal of molecular sciences 2016
Association of genetic polymorphisms in interferon-γ, interleukin-6 and transforming growth factor-β1 gene with oral lichen planus susceptibility
MA Al-Mohaya, L Al-Otaibi, F Al-Harthi, EA Bakr, M Arfin, A Al-Asmari
BMC oral health 2016
Identification of IL6 as a susceptibility gene for major depressive disorder
C Zhang, Z Wu, G Zhao, F Wang, Y Fang
Scientific Reports 2016
Pro-inflammatory cytokines and their epistatic interactions in genetic susceptibility to schizophrenia
L Srinivas, NN Vellichirammal, AM Alex, C Nair, IV Nair, M Banerjee
Journal of Neuroinflammation 2016
Association Between Interleukin-6 -572 C>G and -174 G>C Polymorphisms and Hypertension: A Meta-analysis of Case-control Studies
H Ma, G Sun, W Wang, Y Zhou, D Liu, Y Tong, Z Lu
Medicine 2016
The impact of IL-6 and IL-28B gene polymorphisms on treatment outcome of chronic hepatitis C infection among intravenous drug users in Croatia
Z Bogdanović, I Marinović-Terzić, S Kuret, A Jerončić, N Bradarić, G Forempoher, O Polašek, Š Anđelinović, J Terzić
PeerJ 2016
Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms
JE Nelson, P Handa, B Aouizerat, L Wilson, LA Vemulakonda, MM Yeh, KV Kowdley
Alimentary Pharmacology & Therapeutics 2016
Ancestry informative markers and selected single nucleotide polymorphisms in immunoregulatory genes on preterm labor and preterm premature rupture of membranes: a case control study
BR de Ramos, ND Mendes, AA Tanikawa, MA Amador, NP Santos, SE Santos, EC Castelli, SS Witkin, MG da Silva
BMC pregnancy and childbirth 2016
Effect of interleukin 6 –174G>C gene polymorphism on opioid requirements after total hip replacement
M Białecka, A Jurewicz, A Machoy-Mokrzyńska, M Kurzawski, K Leźnicka, V Dziedziejko, K Safranow, M Droździk, A Bohatyrewicz
Journal of Anesthesia 2016
Interleukin-6 promoter polymorphism interacts with pain and life stress influencing depression phenotypes
D Kovacs, N Eszlari, P Petschner, D Pap, S Vas, P Kovacs, X Gonda, G Bagdy, G Juhasz
Journal of Neural Transmission 2016
Effect of Promoter Polymorphisms on Cytokine Concentration in Preterm Breast Milk and Subsequent Infant Outcomes
KL Baumgartel, MW Groer, SM Cohen, D Ren, DL Spatz, YP Conley
Journal of Human Lactation 2016
Functional Polymorphism in the Interleukin 6 (IL6) Gene with Respect to Depression Induced in the Course of Interferon-α and Ribavirin Treatment in Chronic Hepatitis Patients
D Frydecka, T Pawłowski, D Pawlak, K Małyszczak
Archivum Immunologiae et Therapiae Experimentalis 2016
Genetic Variant in ACVR2B Is Associated with Lean Mass:
YC Klimentidis, JW Bea, P Thompson, WT Klimecki, C Hu, G Wu, JS Nicholas, KK Ryckman, Z Chen
Medicine and Science in Sports and Exercise 2016
Impact of TNF-α (rs1800629) and IL-6 (rs1800795) Polymorphisms on Cognitive Impairment in Asian Breast Cancer Patients
J Chae, T Ng, HL Yeo, M Shwe, YX Gan, HK Ho, A Chan, J Spencer
PloS one 2016
Precision assessment of heterogeneity of lymphedema phenotype, genotypes and risk prediction
MR Fu, YP Conley, D Axelrod, AA Guth, G Yu, J Fletcher, D Zagzag
The Breast 2016
The -174G/C Interleukin-6 Gene Promoter Polymorphism as a Genetic Marker of Differences in Therapeutic Response to Methotrexate and Leflunomide in Rheumatoid Arthritis
AJ Ruiz-Padilla, JI Gamez-Nava, AM Saldaña-Cruz, JD Murillo-Vazquez, ML Vazquez-Villegas, SA Zavaleta-Muñiz, BT Martín-Márquez, JM Ponce-Guarneros, NA Jimenez, A Flores-Chavez, F Sandoval-Garcia, JC Vasquez-Jimenez, EG Cardona-Muñoz, SE Totsuka-Sutto, L Gonzalez-Lopez
BioMed Research International 2016
Promoter Polymorphism (-174, G/C) of Interleukin-6 and Arterial Thromboembolic Events: A Meta-Analysis
SK Kim, JH Chung, OY Kwon
Medical science monitor : international medical journal of experimental and clinical research 2016
Association between the interleukin-6 genetic polymorphism 174 G/C and thrombosis disorder risk: Meta-analysis of 10,549 cases and 19,316 controls
H Ren, Y Zhang, Y Yao, T Guo, H Wang, H Mei, Y Hu
Medicine 2016
Circulating interleukin-6 and rheumatoid arthritis: A Mendelian randomization meta-analysis
B Li, Y Xiao, D Xing, X Ma, J Liu
Medicine 2016
Genetic polymorphisms of interleukin 6 and interleukin 10 in Egyptian patients with systemic lupus eythematosus
RM Talaat, SA Alrefaey, IH Bassyouni, ME Ashour, AA Raouf
Lupus 2016
Evaluation of cytokine genetic polymorphisms in adult patients with common variable immunodeficiency: A single-center study
D Perovic, V Perovic, V Pravica, B Bonaci-Nikolic, R Mijanovic, V Bunjevacki
Immunology Letters 2016
The interleukin 6 c.-174 CC genotype is a predictor for new cardiovascular events in patients with coronary heart disease within three years follow-up
S Reichert, A Schlitt, AC Benten, B Hofmann, HG Schaller, S Schulz
Cytokine 2016
Cytokine gene polymorphism [tumor necrosis factor-alpha (–308), IL-10 (–1082), IL-6 (–174), IL-17F, 1RaVNTR] in pediatric patients with primary immune thrombocytopenia and response to different treatment modalities:
GM Mokhtar, NM El-beblawy, AA Adly, NS Elbarbary, TM Kamal, EM Hasan
Blood Coagulation & Fibrinolysis 2016
Interleukin-6-174G > C (rs1800795) polymorphism distribution and its association with rheumatoid arthritis: A case-control study and meta-analysis
SA Dar, S Haque, RK Mandal, T Singh, M Wahid, A Jawed, AK Panda, N Akhter, M Lohani, MY Areeshi, G Rai, S Datt, SN Bhattacharya, VG Ramachandran, S Das
Autoimmunity 2016
A study of TNF-α, TGF-β, IL-10, IL-6, and IFN-γ gene polymorphisms in patients with depression
S Mihailova, E Ivanova-Genova, T Lukanov, V Stoyanova, V Milanova, E Naumova
Journal of Neuroimmunology 2016
Modulators of the extracellular matrix and risk of anterior cruciate ligament ruptures
M Rahim, S Mannion, B Klug, H Hobbs, W der Merwe, M Posthumus, M Collins, AV September
Journal of Science and Medicine in Sport 2016
Cytokine polymorphisms in sickle cell disease and the relationship with cytokine expression
SC Gilli, FV Pericole, BD Benites, EÂ Sippert, LM Castilho, M Addas-Carvalho, ST Saad
Experimental Hematology 2016
The impact of the IL-1β, IL-1Ra, IL-2, IL-6 and IL-10 gene polymorphisms on the development of Behcet's disease and their association with the phenotype
S Barış, Ö Akyürek, A Dursun, M Akyol
Medicina Clínica 2016
Association of IL1Β (-511 A/C) and IL6 (-174 G > C) polymorphisms with higher disease activity and clinical pattern of psoriatic arthritis
N Cubino, C Montilla, R Usategui-Martín, C Cieza-Borrela, T Carranco, I Calero-Paniagua, A Quesada, JD Cañete, R Queiro, MD Sánchez, C Hidalgo, O Martínez, JD Pino-Montes, A Díaz-Álvarez, R González-Sarmiento
Clinical Rheumatology 2016
Association study of inflammatory genes with rheumatic heart disease in North Indian population: A multi-analytical approach
U Gupta, SS Mir, N Garg, SK Agarwal, S Pande, B Mittal
Immunology Letters 2016
IL-6 −174G/C polymorphism in obese adolescents with nonalcoholic fatty liver disease and its relation to metabolic and biochemical markers:
ME Zaki, HK Nazif, W Kandeel, HA El-Malt, Y El-Hossary, RM El-Sherbini, K Amr
Middle East Journal of Medical Genetics 2016
Association between interleukin-6 (G174C and C572G) promoter gene polymorphisms and risk of ischemic stroke in North Indian population: a case-control study
P Kumar, A Kumar, R Sagar, S Misra, M Faruq, V Suroliya, S Vivekanandhan, AK Srivastava, K Prasad
Neurological Research 2016
Biologic therapies in systemic juvenile idiopathic arthritis
ED Batu
Expert Opinion on Orphan Drugs 2016
Role of Helicobacter pylori and interleukin 6 -174 gene polymorphism in dyslipidemia: a case–control study
VM Pohjanen, OP Koivurova, SE Niemelä, RA Karttunen, TJ Karttunen
BMJ Open 2016
Low-grade inflammation markers in children and adolescents: Influence of anthropometric characteristics and CRP and IL6 polymorphisms
PF Todendi, LG Possuelo, EI Klinger, CP Reuter, MS Burgos, DJ Moura, M Fiegenbaum, AR de Valim
Cytokine 2016
Association of interleukin-6 methylation in leukocyte DNA with serum level and the risk of ischemic heart disease
Q Yang, Y Zhao, Z Zhang, J Chen
Scandinavian Journal of Clinical & Laboratory Investigation 2016
Association of tumour necrosis factor-alpha G/A -238 and G/A -308 single nucleotide polymorphisms with juvenile idiopathic arthritis
M Maddah, S Harsini, V Ziaee, MH Moradinejad, A Rezaei, S Zoghi, M Sadr, Y Aghighi, N Rezaei
International Journal of Immunogenetics 2016
Association of IL-6 Promoter and Receptor Polymorphisms with Multiple Myeloma Risk: A Systematic Review and Meta-Analysis
Y Li, Z Du, X Wang, G Wang, W Li
Genetic Testing and Molecular Biomarkers 2016
Association of Gene Polymorphisms in Interleukin 6 in Infantile Bronchial Asthma
E Babusikova, J Jurecekova, M Jesenak, A Evinova
Archivos de Bronconeumología (English Edition) 2016
Analysis of IL-10 and IL-6 Gene Polymorphisms and Their Serum Levels in Patients with Brucellosis: A Case Control Study
S Kazemi, M Saidijam, SH Hashemi, M Karami, A Vaisi-Raygani, MY Alikhani
Immunological Investigations 2016
Functional polymorphisms in the IL6 gene promoter and the risk of urinary bladder cancer in India
KA Gautam, T Muktanand, SN Sankhwar, A Goel, PL Sankhwar, S Rajender
Cytokine 2016
Increased expression of interleukin-6 (IL-6) gene transcript in relation to IL-6 promoter hypomethylation in gingival tissue from patients with chronic periodontitis
T Kobayashi, K Ishida, H Yoshie
Archives of Oral Biology 2016
Promoter Variation and Expression Levels of Inflammatory Genes IL1A, IL1B, IL6 and TNF in Blood of Spinocerebellar Ataxia Type 3 (SCA3) Patients
M Raposo, C Bettencourt, A Ramos, N Kazachkova, J Vasconcelos, T Kay, J Bruges-Armas, M Lima
NeuroMolecular Medicine 2016
Complete physical mapping of IL6 reveals a new marker associated with chronic periodontitis
SB Farhat, CM de Souza, AP Braosi, SH Kim, VA Tramontina, V Papalexiou, M Olandoski, MT Mira, SM Luczyszyn, PC Trevilatto
Journal of Periodontal Research 2016
IL6-174G > C genetic polymorphism influences antidepressant treatment outcome
S Carvalho, M Santos, L Lima, J Mota-Pereira, P Pimentel, D Maia, D Correia, S Gomes, A Cruz, R Medeiros
Nordic Journal of Psychiatry 2016
Interleukin 6 SNP rs1800797 associates with the risk of adult-onset asthma
TK Lajunen, JJ Jaakkola, MS Jaakkola
Genes and Immunity 2016
Polymorphisms of Cytokine Genes and Polycystic Ovary Syndrome: A Review
JB de Alencar, HV Alves, LN Elpidio, JE Visentainer, AM Sell
Metabolic Syndrome and Related Disorders 2016
Potential Effects of Interleukins on the Pathogenesis of Systemic Onset Juvenile Idiopathic Arthritis
LY Xu, WM Zhang, M Xia, LF Cao
Pediatrics & Neonatology 2016
The effects of IL-1A and IL-6 genes polymorphisms on gene expressions, hormonal and biochemical parameters in polycystic ovary syndrome
B Eser, MI Taskin, AA Hismiogullari, H Aksit, AS Bodur
Journal of Obstetrics & Gynaecology 2016
Polymorphisms of the interleukin 6 gene and additional gene–gene interaction contribute to cervical cancer susceptibility in Eastern Chinese women
X Pu, Z Gu, X Wang
Archives of Gynecology and Obstetrics 2016
Effect of G(-174)C polymorphism in interleukin-6 gene on cardiovascular disease in type 2 diabetes patients
M Buraczynska, P Zukowski, B Drop, I Baranowicz-Gaszczyk, A Ksiazek
Cytokine 2016
Relationships between Common and Novel Interleukin-6 Gene Polymorphisms and Risk of Cervical Cancer: a Case-Control Study
S Zidi, M Stayoussef, BL Alsaleh, E Gazouani, A Mezlini, BH Ebrahim, B Yacoubi-Loueslati, WY Almawi
Pathology & Oncology Research 2016
Influence of IL-6, IL-8, and TGF-β1 gene polymorphisms on the risk of human papillomavirus-infection in women from Pernambuco, Brazil
SF de Júnior, MM Tavares, JL de Macedo, RS de Oliveira, SA Heráclio, MM Maia, PR de Souza, R Moura, S Crovella
Memórias do Instituto Oswaldo Cruz 2016
Association between interleukin 6 -174 G/C promoter gene polymorphism and runners' responses to the dietary ingestion of antioxidant supplementation based on pequi (Caryocar brasiliense Camb.) oil: a before-after study
AL Miranda-Vilela, IF Ribeiro, CK Grisolia
Genetics and molecular biology 2016
Polymorphisms of α1-antitrypsin and Interleukin-6 genes and the progression of hepatic cirrhosis in patients with a hepatitis C virus infection
T Motawi, OG Shaker, RM Hussein, M Houssen
Balkan Journal of Medical Genetics 2016
The role of polymorphism of interleukin 2, 10, 13 and TNF-α genes in cutaneous T-cell lymphoma pathogenesis
B Nedoszytko, B Olszewska, J Roszkiewicz, J Glen, M Zabłotna, H Ługowska-Umer, R Nowicki, M Sokołowska-Wojdyło
POSTEP DERM ALERGOL 2016
Assessment of the −174G/C (rs1800795) and −572G/C (rs1800796) Interleukin 6 Gene Polymorphisms in Egyptian Patients with Rheumatoid Arthritis
K Amr, R El-Awady, H Raslan
Open Access Macedonian Journal of Medical Sciences 2016
Relationship between Interleukin-6 (-174G/C and -572C/G) Promoter Gene Polymorphisms and Risk of Intracerebral Hemorrhage: A Meta-Analysis
P Kumar, S Misra, AK Yadav, A Kumar, M Sriwastva, K Prasad
Pulse (Basel, Switzerland) 2016
TNF-α −308 polymorphisms and male infertility risk: A meta-analysis and systematic review
T Mostafa, M Taymour
Journal of Advanced Research 2016
Role of Helicobacter pylori and interleukin 6 -174 gene polymorphism in dyslipidemia: a case–control study
VM Pohjanen, OP Koivurova, SE Niemelä, RA Karttunen, TJ Karttunen
BMJ Open 2016
Correlation of interleukin-6-174 GC and interleukin-6-572 GC gene polymorphisms with periodontal disease in an Iranian population
Bahareh Nazemi Salman, Surena Vahabi, Alireza Biglari, Simindokht Salavitabar, Maryam Hassani Doabsari
Dental Research Journal 2016
Interleukin 6 SNP rs1800797 associates with the risk of adult-onset asthma.
Lajunen TK, Jaakkola JJ, Jaakkola MS
Genes and Immunity 2016
Association of IL1Β (-511 A/C) and IL6 (-174 G > C) polymorphisms with higher disease activity and clinical pattern of psoriatic arthritis.
Cubino N, Montilla C, Usategui-Martín R, Cieza-Borrela C, Carranco T, Calero-Paniagua I, Quesada A, Cañete JD, Queiro R, Sánchez MD, Hidalgo C, Martínez O, Del Pino-Montes J, Díaz-Álvarez A, González-Sarmiento R
Clinical Rheumatology 2016
Relationships between Common and Novel Interleukin-6 Gene Polymorphisms and Risk of Cervical Cancer: a Case-Control Study.
Zidi S, Stayoussef M, Alsaleh BL, Gazouani E, Mezlini A, Ebrahim BH, Yacoubi-Loueslati B, Almawi WY
Pathology oncology research : POR 2016
Promoter Variation and Expression Levels of Inflammatory Genes IL1A, IL1B, IL6 and TNF in Blood of Spinocerebellar Ataxia Type 3 (SCA3) Patients.
Raposo M, Bettencourt C, Ramos A, Kazachkova N, Vasconcelos J, Kay T, Bruges-Armas J, Lima M
NeuroMolecular Medicine 2016
Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation
A Varelias, KH Gartlan, E Kreijveld, SD Olver, M Lor, RD Kuns, KE Lineburg, BE Teal, NC Raffelt, M Cheong, KA Alexander, M Koyama, KA Markey, E Sturgeon, J Leach, P Reddy, GA Kennedy, GA Yanik, BR Blazar, SK Tey, AD Clouston, KP MacDonald, KR Cooke, GR Hill
Blood 2015
IL-6 as a keystone cytokine in health and disease
CA Hunter, SA Jones
Nature Immunology 2015
Genetic variant of Interleukin-18 gene is associated with the Frailty Index in the English Longitudinal Study of Ageing
K Mekli, A Marshall, J Nazroo, B Vanhoutte, N Pendleton
Age and Ageing 2015
Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)
DJ Raiten, FA Ashour, AC Ross, SN Meydani, HD Dawson, CB Stephensen, BJ Brabin, PS Suchdev, B Ommen
The Journal of nutrition 2015
Inflammaging decreases adaptive and innate immune responses in mice and humans
D Frasca, BB Blomberg
Biogerontology 2015
Therapeutic Potential of Interferon-γ and Its Antagonists in Autoinflammation: Lessons from Murine Models of Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome
A Avau, P Matthys
Pharmaceuticals (Basel, Switzerland) 2015
IL-6 polymorphism in non-small cell lung cancer: a prognostic value?
M Gomes, A Coelho, A Araújo, A Azevedo, AL Teixeira, R Catarino, R Medeiros
Tumor Biology 2015
The Roles of Post-translational Modifications in the Context of Protein Interaction Networks
G Duan, D Walther, P Radivojac
PLoS computational biology 2015
Radon Exposure, IL-6 Promoter Variants, and Lung Squamous Cell Carcinoma in Former Uranium Miners
S Leng, CL Thomas, AM Snider, MA Picchi, W Chen, DG Willis, TG Carr, J Krzeminski, D Desai, A Shantu, Y Lin, MR Jacobson, SA Belinsky
Environmental Health Perspectives 2015
The effect of gene polymorphisms on patient responses to rheumatoid arthritis therapy
M Tarnowski, A Paradowska-Gorycka, E Dąbrowska-Zamojcin, M Czerewaty, S Słuczanowska-Głąbowska, A Pawlik
Expert Opinion on Drug Metabolism & Toxicology 2015
CD38 and Interleukin 6 Gene Polymorphism in Egyptians with Diffuse Large B-Cell Lymphoma (DLBCL)
RM Talaat, AM Abdel-Aziz, EA El-Maadawy, N Abdel-Bary
Immunological Investigations 2015
Identification of a potential proinflammatory genetic profile influencing carotid plaque vulnerability
F Biscetti, G Straface, G Bertoletti, C Vincenzoni, F Snider, V Arena, R Landolfi, A Flex
Journal of Vascular Surgery 2015
Risk model incorporating donor IL6 and IFNG genotype and gastrointestinal GVHD can discriminate patients at high risk of steroid refractory acute GVHD
N Alam, W Xu, EG Atenafu, J Uhm, M Seftel, V Gupta, J Kuruvilla, JH Lipton, HA Messner, DD Kim
Bone Marrow Transplantation 2015
In vitro Production of IL-6 and IFN-γ is Influenced by Dietary Variables and Predicts Upper Respiratory Tract Infection Incidence and Severity Respectively in Young Adults
H Meng, Y Lee, Z Ba, JA Fleming, EJ Furumoto, RF Roberts, PM Kris-Etherton, CJ Rogers
Frontiers in immunology 2015
Predictive genetic markers of coagulation, inflammation and apoptosis in Perthes disease—Serbian experience
S Srzentić, G Nikčević, D Spasovski, Z Baščarević, Z Živković, Z Terzic-Šupić, D Matanović, V Djordjević, S Pavlović, V Spasovski
European Journal of Pediatrics 2015
Association of TNF-alpha, IL-6 and IL-1beta gene polymorphisms with polycystic ovary syndrome: a meta-analysis
R Guo, Y Zheng, J Yang, N Zheng
BMC genetics 2015
Human sickness behavior: Ultimate and proximate explanations: Human Sickness Behavior
EC Shattuck, MP Muehlenbein
American Journal of Physical Anthropology 2015
Association of IL-6 Polymorphism -174G/C and Metabolic Syndrome in Hypertensive Patients
AA Teixeira, BM Quinto, MA Dalboni, CJ de Rodrigues, MC Batista
BioMed Research International 2015
Interleukin-1β and interleukin-6 gene polymorphisms are associated with manifestations of sickle cell anemia
P Vicari, SA Adegoke, DR Mazzotti, RD Cançado, MA Nogutti, MS Figueiredo
Blood Cells, Molecules, and Diseases 2015
Association between IL-6-174G/C Polymorphism and the Risk of Sepsis and Mortality: A Systematic Review and Meta-Analysis
J Gao, A Zhang, W Pan, C Yue, L Zeng, W Gu, J Jiang, W Alazawi
PloS one 2015
Urinary Proteins, Vitamin D and Genetic Polymorphisms as Risk Factors for Febrile Urinary Tract Infection and Relation with Bacteremia: A Case Control Study
WE van der Starre, C Nieuwkoop, U Thomson, MS Zijderveld-Voshart, JP Koopman, TJ van der Reijden, JT van Dissel, E de Vosse, PG de Frutos
PloS one 2015
Interleukin and growth factor gene variants and risk of carpal tunnel syndrome
MC Burger, H Wet, M Collins
Gene 2015
Role of IL-6 −174(G/C) promoter polymorphism in the etiology of early-onset preeclampsia
S Sowmya, A Ramaiah, P Nallari, A Jyothy, A Venkateshwari
Inflammation Research 2015
Current understanding of the pathophysiology of systemic juvenile idiopathic arthritis (sJIA) and target-directed therapeutic approaches
N Bruck, A Schnabel, CM Hedrich
Clinical Immunology 2015
Lipid subclasses profiles and oxidative stress in aggressive periodontitis before and after treatment
L Nibali, M Rizzo, GL Volti, F D'Aiuto, RV Giglio, I Barbagallo, G Pelekos, N Donos
Journal of Periodontal Research 2015
Genetic association of key Th1/Th2 pathway candidate genes, IRF2, IL6, IFNGR2, STAT4 and IL4RA, with atopic asthma in the Indian population
A Kumar, S Das, A Agrawal, I Mukhopadhyay, B Ghosh
Journal of Human Genetics 2015
Exceptional longevity and muscle and fitness related genotypes: a functional in vitro analysis and case-control association replication study with SNPs THRH rs7832552, IL6 rs1800795, and ACSL1 rs6552828
N Fuku, Z He, F Sanchis-Gomar, H Pareja-Galeano, Y Tian, Y Arai, Y Abe, H Murakami, M Miyachi, H Zempo, H Naito, T Yvert, Z Verde, L Venturini, C Fiuza-Luces, A Santos-Lozano, G Rodriguez-Romo, G Ricevuti, N Hirose, E Emanuele, N Garatachea, A Lucia
Frontiers in aging neuroscience 2015
Predicting survival using clinical risk scores and non-HLA immunogenetics
Y Balavarca, K Pearce, J Norden, M Collin, G Jackson, E Holler, R Dressel, HJ Kolb, H Greinix, G Socie, A Toubert, V Rocha, E Gluckman, I Hromadnikova, P Sedlacek, D Wolff, U Holtick, A Dickinson, H Bickeböller
Bone Marrow Transplantation 2015
Genetic polymorphisms of interleukin-6 gene and susceptibility to coronary artery disease in Chinese population: Evidence based on 4582 subjects
SL Liu, YW Yin, QQ Sun, AM Hu, SJ Zhang
Human Immunology 2015
The -308 TNFα and the -174 IL-6 promoter polymorphisms associate with effective anti-TNFα treatment in seronegative spondyloarthritis
M Fabris, L Quartuccio, C Fabro, S Sacco, S Lombardi, R Ramonda, D Biasi, D Punzi, S Adami, I Olivieri, F Curcio, SD Vita
The Pharmacogenomics Journal 2015
Interleukin-18 promoter -607 C/A and -137 G/C polymorphisms and susceptibility to type 1 diabetes: A meta-analysis
YH Lee, JH Kim, GG Song
Human Immunology 2015
Clinical immunology Neonatal infections in Saudi Arabia: Association with cytokine gene polymorphisms
G Allam, AA Alsulaimani, AK Alzaharani, A Nasr
CENT EUR J IMMUNOL 2015
Association between Interleukin-6 (G174C and G572C) promoter gene polymorphisms and risk of ischaemic stroke: A meta-analysis
P Kumar, AK Yadav, A Kumar, R Sagar, AK Pandit, K Prasad
Annals of Neurosciences 2015
Proinflammatory genotype is associated with the frailty phenotype in the English Longitudinal Study of Ageing
K Mekli, JY Nazroo, AD Marshall, M Kumari, N Pendleton
Aging clinical and experimental research 2015
Immunogenetics of juvenile idiopathic arthritis: A comprehensive review
AO Hersh, S Prahalad
Journal of Autoimmunity 2015
Pharmacogenetic Study on the Impact of Rivastigmine Concerning Genetic Variants of A2M and IL-6 Genes on Iranian Alzheimer’s Patients
M Zamani, M Mohammadi, H Zamani, A Tavasoli
Molecular Neurobiology 2015
Less Frequent and Less Severe Flu-Like Syndrome in Interferon Beta-1a Treated Multiple Sclerosis Patients with at Least One Allele Bearing the G>C Polymorphism at Position -174 of the IL-6 Promoter Gene
D Bertoli, F Serana, A Sottini, C Cordioli, D Maimone, MP Amato, D Centonze, C Florio, E Puma, R Capra, L Imberti, RS Klein
PloS one 2015
Influence Of Promoter Polymorphisms Of The Tnf-α (-308g/A) And IL-6 (-174g/C) Genes On Therapeutic Response To Etanercept In Rheumatoid Arthritis
I Jančić, M Šefik-Bukilica, S Živojinović, N Damjanov, V Spasovski, N Kotur, K Klaassen, S Pavlović, B Bufan, N Arsenović-Ranin
Journal of Medical Biochemistry 2015
Association study of interleukin-1 family and interleukin-6 gene single nucleotide polymorphisms in recurrent aphthous stomatitis
S Najafi, H Yousefi, M Mohammadzadeh, AZ Bidoki, IF Moqadam, E Farhadi, AA Amirzargar, N Rezaei
International Journal of Immunogenetics 2015
Genetic Polymorphism and Messenger Ribonucleic Acid Concentrations of TNFα and TGFβ Genes in Patients with Chronic Lower Limb Infections
M Zagozda, A Sarnecka, Z Staszczak, H Gałkowska, P Andziak, WL Olszewski, M Durlik
Surgical Infections 2015
Luteolin 8-C-β-fucopyranoside downregulates IL-6 expression by inhibiting MAPKs and the NF-κB signaling pathway in human monocytic cells
YS Lee, MS Kim, DH Lee, TH Kwon, HH Song, SR Oh, DY Yoon
Pharmacological Reports 2015
Association between IL-6 −174 G/C, IL-6 −634 G/C, and IFN-γ +874 A/T polymorphisms and susceptibility to recurrent pregnancy loss: a meta-analysis
YH Lee, SJ Choi, JD Ji
Journal of Assisted Reproduction and Genetics 2015
Contribution of IL6 −174 G>C and IL1B +3954 C>T polymorphisms to congenital infection with Toxoplasma gondii
W Wujcicka, Z Gaj, J Wilczyński, D Nowakowska
European Journal of Clinical Microbiology & Infectious Diseases 2015
Glucocorticoid pharmacogenetics in pediatric idiopathic nephrotic syndrome
E Cuzzoni, SD Iudicibus, R Franca, G Stocco, M Lucafò, M Pelin, D Favretto, A Pasini, G Montini, G Decorti
Pharmacogenomics 2015
-572 G/C single nucleotide polymorphism of interleukin-6 and sepsis predisposition in chronic renal disease
A Panayides, A Ioakeimidou, V Karamouzos, N Antonakos, I Koutelidakis, G Giannikopoulos, K Makaritsis, N Voloudakis, K Toutouzas, N Rovina, M Bristianou, G Damoraki, C Routsi, EJ Giamarellos-Bourboulis
European Journal of Clinical Microbiology & Infectious Diseases 2015
Association of TNF-α -308G/A and IL-6 -174G/C gene polymorphism with pneumonia-induced sepsis
B Feng, Z Mao, K Pang, S Zhang, L Li
Journal of Critical Care 2015
TNF-α - 308 polymorphisms and male infertility risk: A meta-analysis and systematic review
T Mostafa, M Taymour
Journal of Advanced Research 2015
Association of interleukin-6 gene polymorphism (rs1800796) with severity and functional status of osteoarthritis in elderly individuals
MT Fernandes, KB Fernandes, AS Marquez, IM Cólus, MF Souza, JP Santos, RC Poli-Frederico
Cytokine 2015
Gene polymorphisms in periodontitis. Overview
V Dosseva-Panova, A Mlachkova, C Popova
Biotechnology & Biotechnological Equipment 2015
Aggressive Periodontitis: microbes and host response, who to blame?
L Nibali
Virulence 2015
Effect of interleukin-6 polymorphism on fracture risk
Chuangli Wang, Jianfei Ge, Shanjun Ni
International journal of clinical and experimental medicine 2015
Nutritional Intervention in Metabolic Syndrome
H Takahashi, L Roma, M Silva
Nutritional Intervention in Metabolic Syndrome 2015
Association of gene polymorphism with serum levels of inflammatory and angiogenic factors in Pakistani patients with age-related macular degeneration
Fareeha Ambreen, Muhammad Ismail, Irfan Zia Qureshi
Molecular vision 2015
Analysis of a Functional IL-6 Gene Polymorphism in HLAB27 Associated and Intermediate Uveitis Gives New Insight in Disease Pathogenesis and Commonality with Other Autoimmune Diseases
L Ewald, LW Beate, S Stephanie, R Wilfried, ES Yosuf
Journal of Immunology Research 2015
Association of Plasma Heat Shock Protein 70, Interleukin 6, and Creatine Kinase Concentrations in a Healthy, Young Adult Population
C Contreras-Sesvold, BD Revenis, FG OConnor, PA Deuster
Journal of Biomarkers 2015
Are Immune Modulating Single Nucleotide Polymorphisms Associated with Necrotizing Enterocolitis?
AL Franklin, M Said, CD Cappiello, H Gordish-Dressman, Z Tatari-Calderone, S Vukmanovic, K Rais-Bahrami, NL Luban, JM Devaney, AD Sandler
Scientific Reports 2015
Genetic polymorphism directs IL-6 expression in fibroblasts but not selected other cell types
EH Noss, HN Nguyen, SK Chang, GF Watts, MB Brenner
Proceedings of the National Academy of Sciences 2015
Genetic Associations of Interleukin-related Genes with Graves’ Ophthalmopathy: a Systematic Review and Meta-analysis
KH Wong, SS Rong, KK Chong, AL Young, CP Pang, LJ Chen
Scientific Reports 2015
Interleukin-6 promoter haplotypes are associated with etanercept response in patients with rheumatoid arthritis
H Schotte, H Schmidt, M Gaubitz, S Drynda, J Kekow, P Willeke, B Schlüter
Clinical Rheumatology 2015
The Evaluation of IL6 and ESR1 Gene Polymorphisms in Primary Dysmenorrhea
AZ Ozsoy, N Karakus, S Yigit, B Cakmak, MC Nacar, HY Dogru
Immunological Investigations 2015
Rhabdomyolysis After Out-of-Water Exercise in an Elite Adolescent Water Polo Player Carrying the IL-6 174C Allele Single-Nucleotide Polymorphism:
A Eliakim, SB Zaken, Y Meckel, C Yamin, N Dror, D Nemet
Journal of Strength and Conditioning Research 2015
The polymorphism of some genes of the immune response in patients with atopic dermatitis
YV Maksimova, EV Svechnikova, VN Maximov, KN Kolesnik, AV Aleshkina, EI Akinshina, OB Nemchaninova
Klinicheskaya dermatologiya i venerologiya 2015
Roles of interleukin (IL)-6 gene polymorphisms, serum IL-6 levels, and treatment in obstructive sleep apnea: a meta-analysis
A Zhong, X Xiong, M Shi, H Xu
Sleep and Breathing 2015
Relationships between cytokine (IL-6 and TGF-β 1 ) gene polymorphisms and chromosomal damage in hospital workers
A Santovito, P Cervella, M Chiarizio, G Meschiati, M Delsoglio, E Manitta, G Picco, M Delpero
Journal of Immunotoxicology 2015
Handbook of Juvenile Idiopathic Arthritis
A Ravelli
Handbook of Juvenile Idiopathic Arthritis 2015
Association between polymorphism of interleukin-6 in the region -174G/C and tinnitus in the elderly with a history of occupational noise exposure
MY Doi, AC Dias, RC Poly-Frederico, MG Maria, MN Oliveira, LL Marchiori
Noise & health 2015
Interleukin-6 gene -174G/C polymorphism and bronchial asthma risk: a meta-analysis
Fangwei Li, Xinming Xie, Shaojun Li, Rui Ke, Bo Zhu, Lan Yang, Manxiang Li
International journal of clinical and experimental medicine 2015
Association of interleukin-6-572C/G gene polymorphism and serum or cerebrospinal fluid interleukin-6 level with enterovirus 71 encephalitis in Chinese Han patients with hand, foot, and mouth disease.
Yuan A, Li J, Liu P, Chen Z, Hou M, Wang J, Han Z
Inflammation 2015
Interleukin-6 promoter haplotypes are associated with etanercept response in patients with rheumatoid arthritis.
Schotte H, Schmidt H, Gaubitz M, Drynda S, Kekow J, Willeke P, Schlüter B
Clinical Rheumatology 2015
Roles of interleukin (IL)-6 gene polymorphisms, serum IL-6 levels, and treatment in obstructive sleep apnea: a meta-analysis.
Zhong A, Xiong X, Shi M, Xu H
Sleep & breathing = Schlaf & Atmung 2015
New Approaches for Studying Alcoholic Liver Disease
J Xu, X Liu, B Gao, M Karin, H Tsukamoto, D Brenner, T Kisseleva
Current Pathobiology Reports 2014
Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies
N JOHNS, BH Tan, M MACMILLAN, TS Solheim, JA Ross, VE Baracos, S DAMARAJU, KC Fearon
Journal of Genetics 2014
Interleukin 6 and Rheumatoid Arthritis
Y Yoshida, T Tanaka
BioMed Research International 2014
IL-6 in Inflammation, Immunity, and Disease
T Tanaka, M Narazaki, T Kishimoto
Cold Spring Harbor perspectives in biology 2014
The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?
KR Doty, MV Guillot-Sestier, T Town
Brain Research 2014
Genetic polymorphisms of cytokine genes in type 2 diabetes mellitus
M Banerjee, M Saxena
World journal of diabetes 2014
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression
GM Slavich, MR Irwin
Psychological Bulletin 2014
Gene of the month: Interleukin 6 (IL-6)
P Ataie-Kachoie, MH Pourgholami, DR Richardson, DL Morris
Journal of clinical pathology 2014
A Peripheral Circulating TH1 Cytokine Profile Is Inversely Associated with Prostate Cancer Risk in CLUE II
NA Bhavsar, JH Bream, AK Meeker, CG Drake, SB Peskoe, D Dabitao, AM de Marzo, WB Isaacs, EA Platz
Cancer epidemiology, biomarkers & prevention 2014
HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy
DC Fajgenbaum, F Rhee, CS Nabel
Blood 2014
Rheumatoid arthritis and genetic variations in cytokine genes: a population-based study in Kashmir Valley
S Shafia, Dilafroze, FA Sofi, R Rasool, S Javeed, ZA Shah
Immunological Investigations 2014
Investigation of relationship between IL-6 gene variants and hypertension in Turkish population
E Karaman, MU Kucuk, A Bayramoglu, SU Göçmen, S Ercan, HI Guler, Y Kucukkaya, S Erden
Cytotechnology 2014
The microbiome, parturition, and timing of birth: more questions than answers
AL Prince, KM Antony, DM Chu, KM Aagaard
Journal of Reproductive Immunology 2014
Variants in C-reactive protein and IL-6 genes and susceptibility to obstructive sleep apnea in children: a candidate-gene association study in European American and Southeast European populations
AG Kaditis, D Gozal, A Khalyfa, L Kheirandish-Gozal, OS Capdevila, K Gourgoulianis, EI Alexopoulos, K Chaidas, R Bhattacharjee, J Kim, P Rodopoulou, E Zintzaras
Sleep Medicine 2014
Neuroimmunological aberrations and cerebral asymmetry abnormalities in schizophrenia: select perspectives on pathogenesis
G Venkatasubramanian, M Debnath
Clinical Psychopharmacology and Neuroscience 2014
Relationship between Interleukin-6 gene polymorphism and hippocampal volume in antipsychotic-naïve schizophrenia: evidence for differential susceptibility?
SV Kalmady, G Venkatasubramanian, V Shivakumar, S Gautham, A Subramaniam, DA Jose, A Maitra, V Ravi, BN Gangadhar
PloS one 2014
Association between COX-2 rs 6681231 genotype and interleukin-6 in periodontal connective tissue. A pilot study
F Mesa, F O'Valle, M Rizzo, F Cappello, N Donos, M Parkar, N Chaudhary, F Carini, R Muñoz, L Nibali
PloS one 2014
-174G/C polymorphism in the interleukin-6 promoter is differently associated with prostate cancer incidence depending on race
S Mandal, F Abebe, J Chaudhary
Genetics and molecular research : GMR 2014
Relation between inflammatory cytokine levels in serum and bronchoalveolar lavage fluid and gene polymorphism in young adult patients with bronchiectasis
G Ayhan, D Tas, I Yilmaz, O Okutan, E Demirer, O Ayten, Z Kartaloglu
Journal of Thoracic Disease 2014
International Review of Neurobiology
JM Loftis, A Janowsky
International review of neurobiology 2014
Do Genetic Susceptibility, Toll-like Receptors, and Pathogen-associated Molecular Patterns Modulate the Effects of Wear?
EM Greenfield
Clinical Orthopaedics and Related Research® 2014
Modifying Effect of a Common Polymorphism in the Interleukin-6 Promoter on the Relationship between Long-Term Exposure to Traffic-Related Particulate Matter and Heart Rate Variability
M Adam, M Imboden, E Boes, E Schaffner, N Künzli, HC Phuleria, F Kronenberg, JM Gaspoz, D Carballo, N Probst-Hensch
PloS one 2014
Polymorphisms in the TNFA and IL6 Genes Represent Risk Factors for Autoimmune Thyroid Disease
C Durães, CS Moreira, I Alvelos, A Mendes, LR Santos, JC Machado, M Melo, C Esteves, C Neves, M Sobrinho-Simões, P Soares
PloS one 2014
Genetic polymorphisms and skin aging: the identification of population genotypic groups holds potential for personalized treatments
J Naval, V Alonso, MA Herranz
Clinical, cosmetic and investigational dermatology 2014
Association between interleukin-6 gene polymorphisms and rheumatoid arthritis in Chinese Han population: a case-control study and a meta-analysis
F Li, J Xu, J Zheng, J Sokolove, K Zhu, Y Zhang, H Sun, E Evangelou, Z Pan
Scientific Reports 2014
Evaluation of anakinra for the treatment of systemic juvenile idiopathic arthritis
SJ Vastert, JF Swart, NM Wulffraat
Expert Opinion on Orphan Drugs 2014
Association of Cytokines in Individuals Sensitive and Insensitive to Dust Mites in a Brazilian Population
MC da Caniatti, AA Marchioro, AL Guilherme, LT Tsuneto, LH Carvalho
PloS one 2014
Patients With Chronic Three-Vessel Disease in a 15-Year Follow-Up Study: Genetic and Non-Genetic Predictors of Survival
J Máchal, M Pávková-Goldbergová, O Hlinomaz, L Groch, A Vašků
Medicine 2014
Cytokine balance and cytokine-driven natural killer cell dysfunction in systemic juvenile idiopathic arthritis
A Avau, K Put, CH Wouters, P Matthys
Cytokine & Growth Factor Reviews 2014
A case-control study on proinflammatory genetic Polymorphisms on sudden sensorineural hearing loss: Polymorphisms on SSNHL
G Cadoni, E Gaetani, PM Picciotti, D Arzani, M Quarta, S Giannantonio, G Paludetti, S Boccia
The Laryngoscope 2014
The interleukin-6 and interleukin-1A gene promoter polymorphism is associated with the pathogenesis of acne vulgaris
S Younis, Q Javed
Archives of Dermatological Research 2014
Pathogenesis of adult-onset Still’s disease: new insights from the juvenile counterpart
Y Jamilloux, M Gerfaud-Valentin, F Martinon, A Belot, T Henry, P Sève
Immunologic Research 2014
Age-Related Macular Degeneration: Insights into Inflammatory Genes
R Cascella, M Ragazzo, C Strafella, F Missiroli, P Borgiani, F Angelucci, LT Marsella, A Cusumano, G Novelli, F Ricci, E Giardina
Journal of Ophthalmology 2014
Racial/ethnic disparities in inflammatory gene single-nucleotide polymorphisms as predictors of a high risk for symptom burden in patients with multiple myeloma 1 year after diagnosis: Inflammatory Gene SNPs Predict Symptoms
Q Shi, XS Wang, G Li, ND Shah, RZ Orlowski, LA Williams, TR Mendoza, CS Cleeland
Cancer 2014
Association of a Mutation in LACC1 With a Monogenic Form of Systemic Juvenile Idiopathic Arthritis: Monogenic Systemic Juvenile Idiopathic Arthritis
SM Wakil, DM Monies, M Abouelhoda, N Al-Tassan, H Al-Dusery, EA Naim, B Al-Younes, J Shinwari, FA Al-Mohanna, BF Meyer, S Al-Mayouf
Arthritis & Rheumatology 2014
The Role of Interleukin-6 and Interleukin-8 Gene Polymorphisms in Non-Alcoholic Steatohepatitis
M Cengiz, DG Yasar, MA Ergün, G Akyol, S Ozenirler
Hepatitis Monthly 2014
Relationship of the urine cortisol level with the performance status of patients with lung cancer: a retrospective study
K Suzuki, T Ichikawa, H Furuse, T Tsuda, K Tokui, Y Masaki, S Okazawa, K Kambara, M Inomata, T Yamada, T Miwa, S Matsui, T Kashii, H Taniguchi, R Hayashi, K Tobe
Supportive Care in Cancer 2014
Genetic polymorphism of interleukin-6 influences susceptibility to HBV-related hepatocellular carcinoma in a male Chinese Han population
S Tang, Y Yuan, Y He, D Pan, Y Zhang, Y Liu, Q Liu, Z Zhang, Z Liu
Human Immunology 2014
Polymorphisms of interleukin 6 and interleukin 10 in Egyptian people with Behcet's disease
RM Talaat, ME Ashour, IH Bassyouni, AA Raouf
Immunobiology 2014
Synergistic effect of anti and pro-inflammatory cytokine genes and their promoter polymorphism with ST-elevation of myocardial infarction
S Biswas, PK Ghoshal, N Mandal
Gene 2014
Association of IL-6−174G>C and −572C>G polymorphisms with risk of young ischemic stroke patients
X Yang, L Feng, C Li, Y Li
Gene 2014
Association of interleukin-6 polymorphisms with obesity and metabolic alterations in young Saudi population
KK Alharbi, R Syed, IA Khan
Molecular Biology Reports 2014
Interleukin-6 gene polymorphism, chronic stress and atherosclerosis
N Chumaeva, M Hintsanen, L Pulkki-Råback, M Jokela, M Juonala, T Lehtimäki, OT Raitakari, L Keltikangas-Järvinen
Journal of Psychosomatic Research 2014
IL6-174 G/C gene polymorphism and its relation to serum IL6 in Egyptian children with community-acquired pneumonia
HE Zidan, RM Elbehedy, SF Azab
Cytokine 2014
Association of NLRP3 and CARD8 genetic polymorphisms with juvenile idiopathic arthritis in a Taiwanese population
CA Yang, ST Huang, BL Chiang
Scandinavian Journal of Rheumatology 2014
Regulation of the Interleukin-6 gene expression during monocytic differentiation of HL-60 cells by chromatin remodeling and methylation
MK Poplutz, I Wessels, L Rink, P Uciechowski
Immunobiology 2014
Predictive Value of Selected Biomarkers, Polymorphisms, and Clinical Features for Oligoarticular Juvenile Idiopathic Arthritis-associated Uveitis
L Pelegrín, R Casaroli-Marano, J Antón, MC de Vicuña, N Molina-Prat, JI Aróstegui, J Yagüe, J Ríos, A Adán
Ocular Immunology and Inflammation 2014
Immunologic and psychologic parameters associated with geographic tongue
M Alikhani, N Khalighinejad, P Ghalaiani, MA Khaleghi, E Askari, M Gorsky
Oral Surgery Oral Medicine Oral Pathology and Oral Radiology 2014
Use of floss/interdental brushes is associated with lower risk for new cardiovascular events among patients with coronary heart disease
S Reichert, A Schlitt, V Beschow, A Lutze, S Lischewski, T Seifert, T Dudakliewa, R Gawe, K Werdan, B Hofmann, HG Schaller, S Schulz
Journal of Periodontal Research 2014
Association Between IL-6 -174G/C Polymorphism and Risk of Multiple Sclerosis: A Meta-Analysis
S Hu, Y Chen, XD Sun, FJ Li, QF Shu, XL Liu, SF Jiang
Genetic Testing and Molecular Biomarkers 2014
Association of Interleukin-6 −174 G>C Promoter Polymorphism with Increased Risk of Type 2 Diabetes Mellitus Patients with Diabetic Nephropathy in Turkey
M Karadeniz, M Erdogan, A Berdeli, C Yilmaz
Genetic Testing and Molecular Biomarkers 2014
Association of pregnancy outcome with cytokine gene polymorphisms in HEV infection during pregnancy: Cytokine Gene Polymorphisms and HEV Infection
SG Devi, A Kumar, P Kar, SA Husain, S Sharma
Journal of Medical Virology 2014
Functional FCGR3A 158 V/F and IL-6 −174 C/G polymorphisms predict response to biologic therapy in patients with rheumatoid arthritis: a meta-analysis
YH Lee, SC Bae, GG Song
Rheumatology International 2014
Role of IL6, IL12B and VDR gene polymorphisms in Plasmodium vivax malaria severity, parasitemia and gametocytemia levels in an Amazonian Brazilian population
VA Sortica, MG Cunha, MD Ohnishi, JM Souza, ÂK Ribeiro-dos-Santos, SE Santos, MH Hutz
Cytokine 2014
Increased serum interleukin-6 levels in early stages of psychosis: Associations with at-risk mental states and the severity of psychotic symptoms
A Stojanovic, L Martorell, I Montalvo, L Ortega, R Monseny, E Vilella, J Labad
Psychoneuroendocrinology 2014
Study of the cytokine polymorphisms in correlation to rejection and graft survival in renal allograft donors and recipients from a homogenous Saudi population
A Gaafar, A Iqniebi, A Sheereen, A Eldali, H Turpeinen, C Adra, KA Meshari, KA Hussein
Transplant Immunology 2014
Interleukin-6 G-174C gene polymorphism and susceptibility to upper respiratory tract infection among endurance athletes
F Zehsaz, N Farhangi, A Monfaredan
Journal of Exercise Science & Fitness 2014
Lack of association between −174G>C and −634C>G polymorphisms in interleukin-6 promoter region and lung cancer risk: a meta-analysis
F Jiao, D Xu, Q Li, G Liu, H Liu, T Ren
Tumor Biology 2014
Adult-onset Still's disease
M Gerfaud-Valentin, Y Jamilloux, J Iwaz, P Sève
Autoimmunity Reviews 2014
Update on research and clinical translation on specific clinical areas: From bench to bedside: How insight in immune pathogenesis can lead to precision medicine of severe juvenile idiopathic arthritis
S Vastert, B Prakken
Best Practice & Research Clinical Rheumatology 2014
Données actualisées sur la physiopathologie, les phénotypes et les traitements de la maladie de Still de l’adulte
M Gerfaud-Valentin, P Sève, A Hot, C Broussolle, Y Jamilloux
La Revue de Médecine Interne 2014
Interleukin-6 in renal disease and therapy
SA Jones, DJ Fraser, CA Fielding, GW Jones
Nephrology Dialysis Transplantation 2014
Interleukin-6(-174) Locus Polymorphism and Serum IL-6 Levels in Normal Tension Glaucoma
KH Lin, SC Feng, YC Shen, LC Wei, CY Liang, CJ Chang, YY Yang, CH Chiu, CY Wang
Ophthalmic Genetics 2014
Involvement of IL-6 and IL-1 receptor antagonist on intellectual disability
A Aureli, P Sebastiani, TD Beato, AE Marimpietri, A Graziani, E Sechi, SD Loreto
Immunology Letters 2014
Combined impact of hepatitis C virus genotype 1 and interleukin-6 and tumor necrosis factor-α polymorphisms on serum levels of pro-inflammatory cytokines in Brazilian HCV-infected patients
AM Tarragô, AG da Costa, JP Pimentel, ST Gomes, FB Freitas, P Lalwani, AR de Araújo, FS Victória, MB Victória, AC Vallinoto, A Sadahiro, A Teixeira-Carvalho, OA Martins-Filho, A Malheiro
Human Immunology 2014
Genetic Association of BSF2 Polymorphism and Susceptibility to Lung Cancer
H Wang, Z Liu
Cell Biochemistry and Biophysics 2014
Association between interleukin-6 polymorphism in the −174 G/C region and hearing loss in the elderly with a history of occupational noise exposure
MP Braga, SM Maciel, LL de Marchiori, RC Poli-Frederico
Brazilian Journal of Otorhinolaryngology 2014
Association of Interleukin-6-572C/G Gene Polymorphism and Serum or Cerebrospinal Fluid Interleukin-6 Level with Enterovirus 71 Encephalitis in Chinese Han Patients with Hand, Foot, and Mouth Disease
A Yuan, J Li, P Liu, Z Chen, M Hou, J Wang, Z Han
Inflammation 2014
Polymorphisms in the TNFA and IL6 Genes Represent Risk Factors for Autoimmune Thyroid Disease
C Durães, CS Moreira, I Alvelos, A Mendes, LR Santos, JC Machado, M Melo, C Esteves, C Neves, M Sobrinho-Simões, P Soares, AP Arez
PloS one 2014
Host genetic factors in American cutaneous leishmaniasis: a critical appraisal of studies conducted in an endemic area of Brazil
LC Castellucci, LF de Almeida, SE Jamieson, M Fakiola, EM de Carvalho, JM Blackwell
Memórias do Instituto Oswaldo Cruz 2014
Interleukin-6: the missing element of the neurocognitive deterioration in schizophrenia? The focus on genetic underpinnings, cognitive impairment and clinical manifestation
D Frydecka, B Misiak, E Pawlak-Adamska, L Karabon, A Tomkiewicz, P Sedlaczek, A Kiejna, JA Beszłej
European Archives of Psychiatry and Clinical Neuroscience 2014
Stratification Analysis and Case-control Study of Relationships between Interleukin-6 Gene Polymorphisms and Cervical Cancer Risk in a Chinese Population
WJ Shi, H Liu, D Wu, ZH Tang, YC Shen, L Guo
Asian Pacific Journal of Cancer Prevention 2014
IL6-174G/C polymorphism and fracture risk
Zhichang Zhang, Nengbin He, Tao Zhang
International journal of clinical and experimental medicine 2014
Interleukin-6 genotypes and serum levels in Chinese Hui population
Shu-Ping Gao, Shu Liang, Min Pan, Rong-Liang Sun, Chu Chen, Hong Luan, Min-Hui Jiang
International journal of clinical and experimental medicine 2014
Clinical relevance of IL-6 gene polymorphism in severely injured patients
Vasilije Jeremić, Tamara Alempijević, Srđan Mijatović, Ana Šijački, Sanja Dragašević, Sonja Pavlović, Biljana Miličić, Slobodan Krstić
BOSNIAN J BASIC MED 2014
Interleukin-6 and interleukin-10 gene polymorphisms and recurrent pregnancy loss in Romanian population
Camil L. Bohiltea, Viorica E. Radoi
IRAN J REPROD MED 2014
Clinical Implications of Tumor Necrosis Factor-Alpha, Interleukin-6 and Resistin in Coronary Artery Disease
Q Javed
World Journal of Cardiovascular Diseases 2014
Relationship between Interleukin-6 Gene Polymorphism and Hippocampal Volume in Antipsychotic-Naïve Schizophrenia: Evidence for Differential Susceptibility?
SV Kalmady, G Venkatasubramanian, V Shivakumar, S Gautham, A Subramaniam, DA Jose, A Maitra, V Ravi, BN Gangadhar, M Uddin
PloS one 2014
Modifying Effect of a Common Polymorphism in the Interleukin-6 Promoter on the Relationship between Long-Term Exposure to Traffic-Related Particulate Matter and Heart Rate Variability
M Adam, M Imboden, E Boes, E Schaffner, N Künzli, HC Phuleria, F Kronenberg, JM Gaspoz, D Carballo, N Probst-Hensch, RA Coulombe
PloS one 2014
Association between COX-2 rs 6681231 Genotype and Interleukin-6 in Periodontal Connective Tissue. A Pilot Study
F Mesa, F OValle, M Rizzo, F Cappello, N Donos, M Parkar, N Chaudhary, F Carini, R Muñoz, L Nibali, S Amar
PloS one 2014
Frequencies of interleukin-6, GST and progesterone receptor gene polymorphisms in postmenopausal women with low bone mineral density
KF Moura, M Haidar, C Bonduki, PC Feldner, I Silva, JM Soares, MJ Girao
Sao Paulo Medical Journal 2014
Association of interleukin-6 polymorphisms with obesity and metabolic alterations in young Saudi population.
Alharbi KK, Syed R, Khan IA
Molecular Biology Reports 2014
[Association of genetic polymorphisms in IL-6 and IL-1β gene with risk of lung cancer in female non-smokers].
Su M, Zhou B
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2014
Lack of association between -174G>C and -634C>G polymorphisms in interleukin-6 promoter region and lung cancer risk: a meta-analysis.
Jiao F, Xu D, Li Q, Liu G, Liu H, Ren T
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014
Functional FCGR3A 158 V/F and IL-6 -174 C/G polymorphisms predict response to biologic therapy in patients with rheumatoid arthritis: a meta-analysis.
Lee YH, Bae SC, Song GG
Rheumatology International 2014
[Association between interleukin-6 polymorphism in the -174 G/C region and hearing loss in the elderly with a history of occupational noise exposure].
Braga MP, Maciel SM, Marchiori LL, Poli-Frederico RC
Brazilian Journal of Otorhinolaryngology 2014
Frequencies of interleukin-6, GST and progesterone receptor gene polymorphisms in postmenopausal women with low bone mineral density: Frequência do polimorfismo da interleucina-6, GST, e dos receptores de progesterona em mulheres na pós-menopausa com baixa densidade mineral óssea
Moura KF, Haidar M, Bonduki C, Feldner PC Júnior, Silva I, Soares JM Júnior, Girão MJ
2014
Interleukin-6 polymorphisms: a useful genetic tool for inflammation research?
Steve Humphries, Patricia Woo
Journal of Clinical Investigation 2013
Imbalanced frequencies of Th17 and Treg cells in acute coronary syndromes are mediated by IL-6-STAT3 signaling
Y Ma, X Yuan, L Deng, W Xu, Y Zheng, C Yue, G Zhang, F Xie, YH Yang, MP Gantier, JP Liu, D Xu, L Shen
PloS one 2013
Genes for Elite Power and Sprint Performance: ACTN3 Leads the Way
N Eynon, ED Hanson, A Lucia, PJ Houweling, F Garton, KN North, DJ Bishop
Sports Medicine 2013
Cytokine gene polymorphism and graft-versus-host disease: a survey in Iranian bone marrow transplanted patients
MR Noori-Daloii, N Jalilian, P Izadi, M Sobhani, Z Rabii-Gilani, MS Yekaninejad
Molecular Biology Reports 2013
Association of IL-6 G-174C polymorphism with bone mineral density
Y Ni, H Li, Y Zhang, H Zhang, Y Pan, J Ma, L Wang
Journal of Bone and Mineral Metabolism 2013
Negative emotions predict elevated interleukin-6 in the United States but not in Japan
Y Miyamoto, JM Boylan, CL Coe, KB Curhan, CS Levine, HR Markus, J Park, S Kitayama, N Kawakami, M Karasawa, GD Love, CD Ryff
Brain, Behavior, and Immunity 2013
Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels
K Stone, E Woods, SM Szmania, OW Stephens, TK Garg, B Barlogie, JD Shaughnessy, B Hall, M Reddy, A Hoering, E Hansen, F Rhee
PloS one 2013
The role of non-HLA gene polymorphisms in graft-versus-host disease
A Takami
International Journal of Hematology 2013
Personalisierte Medizin bei Zytokin-gerichteten Therapien
F Behrens, M Köhm
Zeitschrift für Rheumatologie 2013
Allele frequency distributions of -174G/C polymorphism in regulatory region of interleukin 6 gene (IL6) in Russian and worldwide populations
SA Borinskaya, AS Gureev, AA Orlova, ED Sanina, AA Kim, F Gasemianrodsari, VI Shirmanov, OP Balanovsky, DV Rebrikov, AV Koshechkin, NK Yankovsky
Russian Journal of Genetics 2013
Systemic Inflammation Is Associated with Differential Gene Expression and Airway Neutrophilia in Asthma
J Fu, KJ Baines, LG Wood, PG Gibson
OMICS: A Journal of Integrative Biology 2013
IL-6-174 G>C and MMP-9-1562 C>T polymorphisms are associated with increased risk of deep vein thrombosis in cancer patients
G Malaponte, J Polesel, S Candido, D Sambataro, V Bevelacqua, M Anzaldi, N Vella, V Fiore, L Militello, MC Mazzarino, M Libra, SS Signorelli
Cytokine 2013
A Consideration of Biomarkers to be Used for Evaluation of Inflammation in Human Nutritional Studies
PC Calder, N Ahluwalia, R Albers, N Bosco, R Bourdet-Sicard, D Haller, ST Holgate, LS Jönsson, ME Latulippe, A Marcos, J Moreines, C M'Rini, M Müller, G Pawelec, RJ Neerven, B Watzl, J Zhao
British Journal of Nutrition 2013
The Interleukin-6 −147 G/C Polymorphism Is Associated with Increased Risk of Coronary Artery Disease in Young South African Indian Men
A Phulukdaree, S Khan, P Ramkaran, R Govender, D Moodley, AA Chuturgoon
Metabolic Syndrome and Related Disorders 2013
Association between Interleukin-6 −174G/C polymorphism and the risk of Alzheimer's disease :A meta-analysis
Y Hua, X Guo, Q Huang, Y Kong, X Lu
International Journal of Neuroscience 2013
Interleukin-6 gene polymorphism (−174 G/C) is associated with toxoplasmic retinochoroiditis
CA Cordeiro, PR Moreira, TF Bessa, GC Costa, WO Dutra, WR Campos, F Oréfice, LH Young, AL Teixeira
Acta Ophthalmologica 2013
The association of IL-6 and IL-6R gene polymorphisms with chronic periodontitis in a Chinese population
HY Zhang, L Feng, H Wu, XD Xie
Oral Diseases 2013
Serotonin and interleukin-6: The role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms
M Udina, J Moreno-España, R Navinés, D Giménez, K Langohr, M Gratacòs, L Capuron, R la Torre, R Solà, R Martín-Santos
Psychoneuroendocrinology 2013
Comparison of cytokine gene polymorphisms among Greek patients with invasive meningococcal disease or viral meningitis
CJ Titmarsh, SM Moscovis, S Hall, G Tzanakaki, K Kesanopoulos, A Xirogianni, RJ Scott, CC Blackwell
Journal of Medical Microbiology 2013
Circulating interleukin-6 concentration and cognitive decline in old age: the PROSPER study
SP Mooijaart, N Sattar, S Trompet, J Lucke, DJ Stott, I Ford, JW Jukema, RG Westendorp, AJ de Craen
Journal of Internal Medicine 2013
Lack of association of IL-6 polymorphism with rheumatoid arthritis/type 1 diabetes: A meta-analysis
WD Xu, M Zhou, H Peng, HF Pan, DQ Ye
Joint Bone Spine 2013
Effect of interleukin-6 and insulin resistance on early virological response of Egyptian chronic hepatitis C patients to combined pegylated interferon plus ribavirin therapy:
TI el Serafi, MM Awad, LA Eldeen, AT el Serafi, M Husin
Egyptian Liver Journal 2013
Molecular genetic analysis of polymorphisms pertaining to the susceptibility to chronic asthma in Egyptian patients
AA Ali, AA Settin
The Journal of Basic & Applied Zoology 2013
The association of IL1α and IL1β polymorphisms with susceptibility to systemic lupus erythematosus: A meta-analysis
B Wang, JM Zhu, YG Fan, CC Feng, GM Chen, H Chen, HF Pan, DQ Ye
Gene 2013
Incidence and risk factors of anti-HLA immunization after pregnancy
E Masson, C Vidal, M Deschamps, S Bongain, C Thevenin, I Dupont, D Rietmulher, F Pouthier, G Mongaillard, J Chabod, C Ferrand, P Tiberghien, JM Rebibou
Human Immunology 2013
IL1β, IL6 and IL8 gene polymorphisms involvement in recurrent corneal erosion in patients with hereditary stromal corneal dystrophies
AM Kucherenko, VM Pampukha, GI Drozhzhyna, LA Livshits
Cytology and Genetics 2013
Cytokine Gene Polymorphisms in Kidney Transplantation
T Dhaouadi, I Sfar, R Bardi, S Jendoubi-Ayed, TB Abdallah, K Ayed, Y Gorgi
Transplantation Proceedings 2013
Polymorphism of inflammatory genes and arsenic methylation capacity are associated with urothelial carcinoma
CC Wu, YK Huang, CJ Chung, CY Huang, YS Pu, HS Shiue, LA Lai, YC Lin, CT Su, YM Hsueh
Toxicology and Applied Pharmacology 2013
Relation of IL-6, IL-13 and IL-15 gene polymorphisms to the rheumatoid factors, anti-CCP and other measures of rheumatoid arthritis activity
MP Goldbergova, P Nemec, J Lipkova, J Jarkovsky, J Gatterova, D Ambrozkova, A Vasku, M Soucek, N Pavek
International Journal of Immunogenetics 2013
Association between tumor necrosis factor-α promoter −308 A/G, −238 A/G, interleukin-6 −174 G/C and −572 G/C polymorphisms and periodontal disease: a meta-analysis
GG Song, SJ Choi, JD Ji, YH Lee
Molecular Biology Reports 2013
Absence d’association du polymorphisme génétique IL-6 avec la polyarthrite rhumatoïde et le diabète type 1 : une méta-analyse
WD Xu, M Zhou, H Peng, HF Pan, DQ Ye
Revue du Rhumatisme 2013
Genetic component of giant cell arteritis
FD Carmona, MA Gonzalez-Gay, J Martin
Rheumatology 2013
Interleukin-6 promoter polymorphisms −174 G/C in Brazilian patients with systemic lupus erythematosus
NM Asano, HD Angelo, HA da Silva, MM Maia, OG Lins, PE Souza
Human Immunology 2013
Interleukin-4, interleukin-4 receptor, and interleukin-18 polymorphisms and rheumatoid arthritis: a meta-analysis
GG Song, SC Bae, JH Kim, YH Lee
Immunological Investigations 2013
Interleukin 6 gene polymorphism -174 is associated with the diffuse type gastric carcinoma: IL6 -174 and Diffuse Gastric Carcinoma
VM Pohjanen, OP Koivurova, JM Mäkinen, JM Karhukorpi, T Joensuu, PO Koistinen, JM Valtonen, SE Niemelä, RA Karttunen, TJ Karttunen
Genes, Chromosomes and Cancer 2013
Macrophage subsets and osteoimmunology: tuning of the immunological recognition and effector systems that maintain alveolar bone
C Sima, M Glogauer
Periodontology 2000 2013
Influence of interleukin-6 gene -174G>C polymorphism on development of atherosclerosis: A meta-analysis of 50 studies involving 33,514 subjects
YW Yin, JC Li, M Zhang, JZ Wang, BH Li, Y Liu, SQ Liao, MJ Zhang, CY Gao, LL Zhang
Gene 2013
Interleukin-6 level and gene polymorphism in spontaneous miscarriage: IL6 level and polymorphism in spontaneous miscarriage
M Drozdzik, N Szlarb, M Kurzawski
Tissue Antigens 2013
Gingival fibroblasts from periodontitis patients exhibit inflammatory characteristics in vitro
KJ Baek, Y Choi, S Ji
Archives of Oral Biology 2013
Effects of interleukin (IL)-6 gene polymorphisms on recurrent aphthous stomatitis
N Karakus, S Yigit, A Rustemoglu, G Kalkan, N Bozkurt
Archives of Dermatological Research 2013
Nutrition and Enhanced Sports Performance
ED Hanson, N Eynon
Nutrition and Enhanced Sports Performance 2013
Significant association of TNFα and IL-6 gene with male infertility—An explorative study in Indian populations of Uttar Pradesh
KK Shukla, S Agnihotri, A Gupta, AA Mahdi, ES Mohamed, SN Sankhwar, P Sharma
Immunology Letters 2013
Interleukin-6 −174G/C gene polymorphism affects muscle damage response to acute eccentric resistance exercise in elderly obese women
SS Funghetto, J Prestes, AO Silva, DL Farias, TG Teixeira, D Vieira, VC Souza, NM Sousa, JW Navalta, GF Melo, MG Karnikowski
Experimental Gerontology 2013
Association Between Interleukin-6 Gene Polymorphisms and Bone Mineral Density: A Meta-Analysis
Z Wang, Y Yang, M He, R Wang, J Ma, Y Zhang, L Zhao, K Yu
Genetic Testing and Molecular Biomarkers 2013
Effect of interleukin-6 polymorphism on risk of preterm birth within population strata: a meta-analysis
W Wu, EA Clark, GJ Stoddard, WS Watkins, MS Esplin, TA Manuck, J Xing, MW Varner, LB Jorde
BMC genetics 2013
Promoter variants in interleukin-6 and tumor necrosis factor alpha and risk of coronary artery disease in a population from Western India
AA Bhanushali, BR Das
Indian journal of human genetics 2013
Interleukin 6(-174G/C) Variant and its Circulating Levels in Coronary Artery Disease Patients and Their First Degree Relatives
RK Galimudi, MK Spurthi, C Padala, KG Kumar, S Mudigonda, SG Reddy, MT Aiyengar, SK Sahu, SH Rani
Inflammation 2013
An interleukin-6 gene promoter polymorphism is associated with polycystic ovary syndrome in South Indian women
VR Tumu, S Govatati, P Guruvaiah, M Deenadayal, S Shivaji, M Bhanoori
Journal of Assisted Reproduction and Genetics 2013
Genetic variants in transforming growth factor-β gene (TGFB1) affect susceptibility to schizophrenia
D Frydecka, B Misiak, JA Beszlej, L Karabon, E Pawlak-Adamska, A Tomkiewicz, A Partyka, A Jonkisz, A Kiejna
Molecular Biology Reports 2013
Ethnic variation in interleukin-6 -174 (g/c) polymorphism in the malaysian population
GG Gan, R Subramaniam, LH Lian, V Nadarajan
Balkan Journal of Medical Genetics 2013
Rather than Rs1800796 polymorphism, expression of interleukin-6 is associated with disease progression of chronic HBV infection in a Chinese Han population
S Tang, Z Liu, Y Zhang, Y He, D Pan, Y Liu, Q Liu, Z Zhang, Y Yuan
Disease Markers 2013
Sequencing of the IL6 gene in a case-control study of cerebral palsy in children
P Khankhanian, SE Baranzini, BA Johnson, L Madireddy, D Nickles, LA Croen, YW Wu
BMC Medical Genetics 2013
The -174G/C and -572G/C interleukin 6 promoter gene polymorphisms in mexican patients with rheumatoid arthritis: a case-control study
SA Zavaleta-Muñiz, BT Martín-Márquez, L Gonzalez-Lopez, NG Gonzalez-Montoya, ML Díaz-Toscano, JM Ponce-Guarneros, AJ Ruiz-Padilla, MV Mercado, M Maldonado-González, M Fafutis-Morris, SE Flores-Martínez, EA Martínez-García, JI Gamez-Nava
Clinical & developmental immunology 2013
Impact of interleukin-6 -174 G>C gene promoter polymorphism on neuroblastoma
F Totaro, F Cimmino, P Pignataro, G Acierno, MD Mariano, L Longo, GP Tonini, A Iolascon, M Capasso
PloS one 2013
Hypergammaglobulinemia in the pediatric population as a marker for underlying autoimmune disease: a retrospective cohort study
MS Lo, D Zurakowski, MB Son, RP Sundel
Pediatric Rheumatology 2013
HNRNPA1 interacts with a 5'-flanking distal element of interleukin-6 and upregulates its basal transcription
D Zheng, J Worthington, JF Timms, P Woo
Genes and Immunity 2013
IL-6 pathway-driven investigation of response to IL-6 receptor inhibition in rheumatoid arthritis
J Wang, A Platt, R Upmanyu, S Germer, G Lei, C Rabe, R Benayed, A Kenwright, A Hemmings, M Martin, O Harari
BMJ Open 2013
Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration: A Case-Control Study
F Ricci, G Staurenghi, T Lepre, F Missiroli, S Zampatti, R Cascella, P Borgiani, LT Marsella, CM Eandi, A Cusumano, G Novelli, E Giardina
PloS one 2013
Genetic association of interleukin-6 polymorphism (-174 G/C) with chronic liver diseases and hepatocellular carcinoma
L Giannitrapani, M Soresi, D Balasus, A Licata, G Montalto
World journal of gastroenterology : WJG 2013
MTHFR Glu429Ala and ERCC5 His46His polymorphisms are associated with prognosis in colorectal cancer patients: analysis of two independent cohorts from Newfoundland
AA Negandhi, A Hyde, E Dicks, W Pollett, BH Younghusband, P Parfrey, RC Green, S Savas
PloS one 2013
Microbiology and treatment of acute apical abscesses
JF Siqueira, IN Rôças
Clinical microbiology reviews 2013
Cytokine genetic variations and fatigue among patients with breast cancer
JE Bower, PA Ganz, MR Irwin, S Castellon, J Arevalo, SW Cole
Journal of Clinical Oncology 2013
Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1
J Denner, M Eschricht, M Lauck, M Semaan, P Schlaermann, H Ryu, L Akyüz
PloS one 2013
Role of the Promoter Polymorphism IL-6 −174G/C in Dermatomyositis and Systemic Lupus Erythematosus
M Hristova, L Dourmishev, Z Kamenarska, S Nikolova, R Kaneva, A Vinkov, M Baleva, D Monova, V Mitev
BioMed Research International 2013
Variations in association of Interleukin 6 -G174C single nucleotide polymorphism with type 2 diabetes mellitus—a review
A Nadeem, AK Naveed, MM Hussain, M Aslam, A Siddiqui, SA Saeed
International Journal of Diabetes in Developing Countries 2013
The Role of Pharmacogenetics in the Treatment of Chronic Hepatitis C Infection
M Kawaguchi-Suzuki, RF Frye
Nature Communications 2013
Genetics of toll like receptor 9 in ANCA associated vasculitides
CA Husmann, JU Holle, F Moosig, S Mueller, B Wilde, JW Tervaert, L Harper, G Assmann, WL Gross, JT Epplen, S Wieczorek
Annals of the rheumatic diseases 2013
Polymorphisms in human leukocyte antigens, human platelet antigens, and cytokine genes in hantavirus cardiopulmonary syndrome patients from Ribeirão Preto, Brazil: Human Polymorphisms in Hantavirus Disease
AA Borges, EA Donadi, GM Campos, GG de Figueiredo, FP Saggioro, SJ Badra, NH Deghaide, LT Figueiredo
Journal of Medical Virology 2013
Low Prevalence of Interleukin-6 Haplotypes Associated with a Decreased Risk of Type 2 Diabetes in Mexican Subjects with a Family History of Type 2 Diabetes
I Zamora-Ginez, AG García-Zapién, SE Flores-Martínez, J Sánchez-Corona, BG Baez-Duarte, E Torres-Rasgado, JR Romero, R Pérez-Fuentes, F Mendoza-Carrera
Archives of Medical Research 2013
Interleukin-10 promoter (−1082) polymorphism in association with repeated hospital-acquired infections in elderly patients
PN Bories, M Laurent, E Liuu, L Denjean, T Popovici, E Paillaud
Aging clinical and experimental research 2013
Lack of an Association Between Interleukin-6 −174G/C Polymorphism and Circulating Interleukin-6 Levels in Normal Population: A Meta-Analysis
M Huang, L Wang, H Ma, J Wang, M Xiang
DNA and Cell Biology 2013
Interleukin-6 polymorphisms and hematologic malignancy: a re-appraisal of evidence from genetic association studies
PD Ziakas, P Karsaliakos, ML Prodromou, E Mylonakis
Biomarkers 2013
Cytokine single nucleotide polymorphisms in patients’ with gallstone: dose TGF-β gene variants affect gallstone formation?
P Ebadi, S Daneshmandi, A Ghasemi, MH Karimi
Molecular Biology Reports 2013
Association of IL-6 polymorphisms with hepatocellular carcinoma risk: evidences from a meta-analysis
Y Liu, S Gao, B Du, J Wang
Tumor Biology 2013
Prognostic value of IL-27 polymorphisms and the susceptibility to epithelial ovarian cancer in a Chinese population
Z Zhang, B Zhou, Y Wu, Q Gao, K Zhang, Y Song, L Zhang, M Xi
Immunogenetics 2013
Influence of interleukin gene polymorphisms on development of acute pancreatitis: a systematic review and meta-analysis
YW Yin, QQ Sun, JQ Feng, AM Hu, HL Liu, Q Wang
Molecular Biology Reports 2013
The role of IL6 and ESR1 gene polymorphisms as immunological factors of pregnancy maintenance
AM Kucherenko, II Vorobiova, NV Rudakova, LA Livshits
Biopolymers and Cell 2013
The genetics of juvenile idiopathic arthritis: current understanding and future prospects
JE Cobb, A Hinks, W Thomson
Rheumatology 2013
Cytokine Gene Polymorphisms in Childhood Dilated Cardiomyopathy: Interferon- gamma, Tumor Necrosis Factor-alpha and Transforming Growth Factor - beta 1 Genes Are Associated with the Disease in Turkish Patients
SO Balci, N Col-Araz, O Baspinar, T Sever, A Balat, S Pehlivan
IRAN J PEDIATR 2013
The Emerging Field of Human Social Genomics
GM Slavich, SW Cole
2013
The Association of the Immune Response Genes to Human Papillomavirus-Related Cervical Disease in a Brazilian Population
AV Marangon, GA Guelsin, JE Visentainer, SD Borelli, MA Watanabe, ME Consolaro, KR Caleffi-Ferracioli, CC Rudnick, AM Sell
BioMed Research International 2013
Imbalanced Frequencies of Th17 and Treg Cells in Acute Coronary Syndromes Are Mediated by IL-6-STAT3 Signaling
Y Ma, X Yuan, L Deng, W Xu, Y Zheng, C Yue, G Zhang, F Xie, YH Yang, MP Gantier, JP Liu, D Xu, L Shen, MG Frasch
PloS one 2013
Recipient IL-6-572C/G genotype is associated with reduced incidence of acute rejection following liver transplantation
J Yao, XW Feng, XB Yu, HY Xie, LX Zhu, Z Yang, BJ Wei, SS Zheng, L Zhou
J INT MED RES 2013
Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration: A Case-Control Study
F Ricci, G Staurenghi, T Lepre, F Missiroli, S Zampatti, R Cascella, P Borgiani, LT Marsella, CM Eandi, A Cusumano, G Novelli, E Giardina, M Federici
PloS one 2013
Modulation of Cytokine Release and Gene Expression by the Immunosuppressive Domain of gp41 of HIV-1
J Denner, M Eschricht, M Lauck, M Semaan, P Schlaermann, H Ryu, L Akyüz, A Landay
PloS one 2013
MTHFR Glu429Ala and ERCC5 His46His Polymorphisms Are Associated with Prognosis in Colorectal Cancer Patients: Analysis of Two Independent Cohorts from Newfoundland
AA Negandhi, A Hyde, E Dicks, W Pollett, BH Younghusband, P Parfrey, RC Green, S Savas, XP Miao
PloS one 2013
Cytokine Genetic Variations and Fatigue Among Patients With Breast Cancer
JE Bower, PA Ganz, MR Irwin, S Castellon, J Arevalo, SW Cole
Journal of Clinical Oncology 2013
Impact of Interleukin-6 –174 G>C Gene Promoter Polymorphism on Neuroblastoma
F Totaro, F Cimmino, P Pignataro, G Acierno, MD Mariano, L Longo, GP Tonini, A Iolascon, M Capasso, B Mittal
PloS one 2013
Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels
K Stone, E Woods, SM Szmania, OW Stephens, TK Garg, B Barlogie, JD Shaughnessy, B Hall, M Reddy, A Hoering, E Hansen, F Rhee, M Scheurer
PloS one 2013
Relevance of IL-6 and MMP-9 to cerebral arteriovenous malformation and hemorrhage
X Li, R Wang, X Wang, X Xue, D Ran, S Wang
Molecular medicine reports 2013
Association of Cytokines, High Sensitive C-Reactive Protein, VEGF and Beta-Defensin-1 Gene Polymorphisms and Their Protein Expressions with Chronic Periodontitis in the Chinese Population
Y Tian, J Li, L Hao, Y Yue, M Wang, WT Loo, MN Cheung, LW Chow, Q Liu, AY Yip, EL Ng, CY Chow
The International Journal of Biological Markers 2013
Role of Interleukin 6–174G>C Polymorphism in Primary Open-Angle Glaucoma
C Zimmermann, M Weger, C Faschinger, W Renner, G Mossböck
European journal of ophthalmology 2013
CCL2/MCP-1 and IL-6 Genetic Polymorphisms for the Prediction of Hematotoxicity Caused by Definitive Chemoradiotherapy
K KURIBAYASHI, S MOTOYAMA, Y SATO, K YOSHINO, T SASAKI, A WAKITA
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 2013
Association between tumor necrosis factor-α promoter -308 A/G, -238 A/G, interleukin-6 -174 G/C and -572 G/C polymorphisms and periodontal disease: a meta-analysis.
Song GG, Choi SJ, Ji JD, Lee YH
Molecular Biology Reports 2013
Influence of interleukin gene polymorphisms on development of acute pancreatitis: a systematic review and meta-analysis.
Yin YW, Sun QQ, Feng JQ, Hu AM, Liu HL, Wang Q
Molecular Biology Reports 2013
Cytokine single nucleotide polymorphisms in patients' with gallstone: dose TGF-β gene variants affect gallstone formation?
Ebadi P, Daneshmandi S, Ghasemi A, Karimi MH
Molecular Biology Reports 2013
Association of IL-6 polymorphisms with hepatocellular carcinoma risk: evidences from a meta-analysis.
Liu Y, Gao SJ, Du BX, Wang JJ
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2013
Prognostic value of IL-27 polymorphisms and the susceptibility to epithelial ovarian cancer in a Chinese population.
Zhang Z, Zhou B, Wu Y, Gao Q, Zhang K, Song Y, Zhang L, Xi M
Immunogenetics 2013
[Personalized medicine in cytokine-targeted therapy].
Behrens F, Köhm M
2013
Genetic Associations in Acquired Immune-Mediated Bone Marrow Failure Syndromes: Insights in Aplastic Anemia and Chronic Idiopathic Neutropenia
I Mavroudi, HA Papadaki
Clinical and Developmental Immunology 2012
Cancer Epigenetics
RG Dumitrescu, M Verma
Cancer Epigenetics 2012
Cancer Epigenetics
RG Dumitrescu, M Verma
Cancer Epigenetics 2012
Cancer Epigenetics
RG Dumitrescu, M Verma
Cancer Epigenetics 2012
Efficacy, safety and tolerability of tocilizumab in patients with systemic juvenile idiopathic arthritis
S Yokota, T Tanaka, T Kishimoto
Therapeutic Advances in Musculoskeletal Diseases 2012
Tocilizumab in the treatment of systemic juvenile idiopathic arthritis
N Nishimoto, Murakami, Tomiita
Open Access Rheumatology : Research and Reviews 2012
Immunogenetics
FT Christiansen, BD Tait
Immunogenetics 2012
Immunogenetics
FT Christiansen, BD Tait
Immunogenetics 2012
Immunogenetics
FT Christiansen, BD Tait
Immunogenetics 2012
Immunogenetics
FT Christiansen, BD Tait
Immunogenetics 2012
Immunogenetics
FT Christiansen, BD Tait
Immunogenetics 2012
A two-SNP IL-6 promoter haplotype is associated with increased lung cancer risk
J Chen, RY Liu, L Yang, J Zhao, X Zhao, D Lu, N Yi, B Han, XF Chen, K Zhang, J He, Z Lei, Y Zhou, B Pasche, X Li, HT Zhang
Journal of Cancer Research and Clinical Oncology 2012
Developing connections amongst key cytokines and dysregulated germinal centers in autoimmunity
RA Sweet, SK Lee, CG Vinuesa
Current Opinion in Immunology 2012
Melphalan exposure induces an interleukin-6 deficit in bone marrow stromal cells and osteoblasts
SL Rellick, D Piktel, C Walton, B Hall, W Petros, JE Fortney, M Gencheva, J Denvir, G Hobbs, M Craig, LF Gibson
Cytokine 2012
A Functional Single-Nucleotide Polymorphism in the Promoter of the Gene Encoding Interleukin 6 Is Associated With Susceptibility to Tuberculosis
G Zhang, B Zhou, W Wang, M Zhang, Y Zhao, Z Wang, L Yang, J Zhai, CG Feng, J Wang, X Chen
The Journal of Infectious Diseases 2012
Is Still's Disease an Autoinflammatory Syndrome?
L Rossi-Semerano, I Koné-Paut
International Journal of Inflammation 2012
Association between IL6 -174G/C and cancer: A meta-analysis of 105,482 individuals
RY Liu, X Song, P Chen, Z Lei, J Miao, N Yi, K Zhang, B Pasche, HT Zhang
Experimental and therapeutic medicine 2012
Polymorphisms of −174G>C and −572G>C in the Interleukin 6 (IL-6) Gene and Coronary Heart Disease Risk: A Meta-Analysis of 27 Research Studies
G Zheng, H Chen, SQ Xiong
PloS one 2012
Impact of the −174 G > C IL-6 Polymorphism on Bioelectrical Parameters in Obese Subjects after Laparoscopic Adjustable Gastric Banding
LD Renzo, MG Carbonelli, A Bianchi, E Domino, MR Migliore, G Rillo, L Iacopino, ND Daniele, AD Lorenzo
Journal of Obesity 2012
Human parainfluenza virus serotypes differ in their kinetics of replication and cytokine secretion in human tracheobronchial airway epithelium
A Schaap-Nutt, R Liesman, EJ Bartlett, MA Scull, PL Collins, RJ Pickles, AC Schmidt
Virology 2012
Histamine: an undercover agent in multiple rare diseases?
A Pino-Ángeles, A Reyes-Palomares, E Melgarejo, F Sánchez-Jiménez
Journal of Cellular and Molecular Medicine 2012
Genetic Polymorphisms and Bronchiolitis Obliterans Syndrome After Lung Transplantation : Promising Results and Recommendations for the Future
EA Kastelijn, CH van Moorsel, HJ Ruven, JW Lammers, JC Grutters
Transplantation 2012
−174G/C IL-6 gene promoter polymorphism predicts therapeutic response to TNF-α blockers :
LD Renzo, A Bianchi, R Saraceno, V Calabrese, C Cornelius, L Iacopino, S Chimenti, AD Lorenzo
Pharmacogenetics and Genomics 2012
Genetic susceptibility to otitis media in childhood
MS Rye, JM Blackwell, SE Jamieson
The Laryngoscope 2012
Association of interleukin-6 circulating levels with coronary artery disease: A meta-analysis implementing mendelian randomization approach
W Niu, Y Liu, Y Qi, Z Wu, D Zhu, W Jin
International Journal of Cardiology 2012
Association of NOS2 and potential effect of VEGF, IL6, CCL2 and IL1RN polymorphisms and haplotypes on susceptibility to GCA--a simultaneous study of 130 potentially functional SNPs in 14 candidate genes
A Enjuanes, Y Benavente, J Hernandez-Rodriguez, C Queralt, J Yague, P Jares, S Sanjose, E Campo, MC Cid
Rheumatology 2012
The association between proinflammatory cytokine polymorphisms and cerebral palsy in very preterm infants
HK Vidak, TC Ivković, M Jokić, R Spaventi, S Kapitanović
Cytokine 2012
Genetic Susceptibility and the Relationship between Cardiovascular Disease, Immunology, and Psychiatric Illness
S Villafuerte, M Rubenfire, Z Kronfol
Psychiatry and Heart Disease The Mind Brain and Heart 2012
A Meta-Analysis of the Effects of Interleukin-6 −174 G&gt;C Genetic Polymorphism on Acute Graft-Versus-Host Disease Susceptibility
B Choi, DE Lee, HY Park, S Jeong, SM Lee, E Ji, S Park, JM Oh
Clinical Therapeutics 2012
Polymorphic variants of the genes encoding intrleukin-6 and fibrinogen: Risk for ischemic stroke and fibrinogen levels
BV Titov, RM Barsova, MY Martynov, AA Nikonova, AV Favorov, EI Gusev, OO Favorova
Molecular Biology 2012
Role of cytokine gene (IFN-γ, TNF-α, TGF-β1, IL-6, and IL-10) polymorphisms in pathogenesis of acute rheumatic fever in Turkish children
N Col-Araz, S Pehlivan, O Baspinar, S Oguzkan-Balci, T Sever, A Balat
European Journal of Pediatrics 2012
Tumor necrosis factor-α -308 G&gt;A and interleukin-6 -174 G&gt;C promoter polymorphisms and pemphigus
YM Mosaad, H Fathy, Z Fawzi, MA El-Saied
Human Immunology 2012
The CC homozygosis of the −174G&gt;C IL-6 polymorphism predicts a lower efficacy of rituximab therapy in rheumatoid arthritis
M Fabris, L Quartuccio, S Lombardi, M Saracco, F Atzeni, A Carletto, M Cimmino, C Fabro, E Pontarini, R Pellerito, LM Bambara, P Sarzi-Puttini, M Cutolo, M Manfredi, M Benucci, P Morassi, F Fischetti, M Padovan, M Govoni, F Curcio, E Tonutti, SD Vita
Autoimmunity Reviews 2012
Cytokine Gene Polymorphisms in the Susceptibility to Acute Coronary Syndrome
BM Babu, BP Reddy, VH Priya, A Munshi, HS Rani, GS Latha, VD Rao, A Jyothy
Genetic Testing and Molecular Biomarkers 2012
Polymorphisms of interleukin-1 and interleukin-6 genes on the risk of ischemic stroke in a meta-analysis
F Ye, XQ Jin, GH Chen, XL Den, YQ Zheng, CY Li
Gene 2012
The association between interleukin-6 polymorphisms and rheumatoid arthritis: a meta-analysis
YH Lee, SC Bae, SJ Choi, JD Ji, GG Song
Inflammation Research 2012
Genetic and Immunological Evidence Implicates Interleukin 6 as a Susceptibility Gene for Leprosy Type 2 Reaction
AL Sousa, VM Fava, LH Sampaio, CM Martelli, MB Costa, MT Mira, MM Stefani
The Journal of Infectious Diseases 2012
The -174G/C variant of IL6 as risk factor for mortality and technique failure in a large cohort of peritoneal dialysis patients
M Verduijn, C Marechal, AM Coester, DE Sampimon, EW Boeschoten, FW Dekker, E Goffin, RT Krediet, O Devuyst
Nephrology Dialysis Transplantation 2012
Interleukin-6 promoter polymorphism and plasma levels in patients with schizophrenia
R Zakharyan, M Petrek, A Arakelyan, F Mrazek, S Atshemyan, A Boyajyan
Tissue Antigens 2012
Does Clinically Relevant Temperature Change miRNA and Cytokine Expression in Whole Blood?
AT Billeter, M Qadan, D Druen, SA Gardner, T The, HC Polk
Journal of Interferon & Cytokine Research 2012
Polymorphic variations in IL-1β, IL-6 and IL-10 genes, their circulating serum levels and breast cancer risk in Indian women
S Pooja, P Chaudhary, LV Nayak, S Rajender, KS Saini, D Deol, S Kumar, HK Bid, R Konwar
Cytokine 2012
Association Between −174 Interleukin-6 Gene Polymorphism and Biological Response to Rituximab in Several Systemic Autoimmune Diseases
G Robledo, CL Dávila-Fajardo, A Márquez, N Ortego-Centeno, JL Rubio, ER Garrido, J Sánchez-Román, FJ García-Hernández, R Ríos-Fernández, MF González-Escribano, MT García, MJ Palma, MM Ayala, J Martín
DNA and Cell Biology 2012
Is there any relation between IL-6 gene −174 G>C polymorphism and postmenopausal osteoporosis?
D Deveci, ZS Ozkan, H Yuce
European Journal of Obstetrics & Gynecology and Reproductive Biology 2012
Influence of IL-6 haplotypes on clinical and inflammatory response in aggressive periodontitis
L Nibali, G Pelekos, F D’Aiuto, N Chaudhary, R Habeeb, D Ready, M Parkar, N Donos
Clinical Oral Investigations 2012
Initial manifestations and clinical course of systemic onset juvenile idiopathic arthritis: A ten-year retrospective study
HY Tsai, JH Lee, HH Yu, LC Wang, YH Yang, BL Chiang
Journal of the Formosan Medical Association 2012
Association between interleukin-6 gene −174 G/C polymorphism and the risk of coronary heart disease: A meta-analysis of 20 studies including 9619 cases and 10,919 controls
Y Yin, A Hu, Q Sun, H Liu, Q Wang, Y Zeng, R Xu, Z Hou, Z Zhang, S Zhang, M Zhou
Gene 2012
Do gene polymorphism in IL-1β, TNF-α and IL-6 influence therapeutic response in patients with drug refractory epilepsy?
P Tiwari, R Dwivedi, N Mansoori, R Alam, UK Chauhan, M Tripathi, AK Mukhopadhyay
Epilepsy Research 2012
No evidence of association between functional polymorphisms located within IL6R and IL6ST genes and systemic sclerosis: IL6R and IL6ST functional polymorphisms in SSc susceptibility
MC Cénit, CP Simeón, V Fonollosa, G Espinosa, E Beltrán, L Sáez-Comet, E Vicente-Rabaneda, FJ García-Hernández, L Martínez-Estupiñán, M Rodríguez-Carballeira, V Hernández, PG Peña, M Fernández-Castro, FJ Narváez, A Pros, M Gallego, R Ríos-Fernández, MT Camps, A Fernández-Nebro, MV Egurbide, P Carreira, MA González-Gay, J Martín
Tissue Antigens 2012
Association of Single Nucleotide Polymorphisms of Interleukins-1β, -6, and -12B with Contact Lens Keratitis Susceptibility and Severity
NA Carnt, MD Willcox, S Hau, LL Garthwaite, VE Evans, CF Radford, JK Dart, S Chakrabarti, F Stapleton
Ophthalmology 2012
Associations between interleukin-6 gene −174 C/G and −572 C/G polymorphisms and the risk of gastric cancer: A meta-analysis
YW Yin, QQ Sun, AM Hu, Q Wang, HL Liu, ZZ Hou, YH Zeng, RJ Xu, LB Shi, JB Ma
Journal of Surgical Oncology 2012
Influence of Cytokine Gene Polymorphisms on Graft Rejection in Turkish Patients with Renal Transplants from Living Related Donors
Y Seyhun, J Mytilineos, A Turkmen, F Oguz, C Kekik, K Ozdilli, I Nane, F Aydin, M Carin
Transplantation Proceedings 2012
Interleukin-6 promoter variants, prostate cancer risk, and survival
EA Tindall, G Severi, HN Hoang, MC Southey, DR English, JL Hopper, GG Giles, VM Hayes
The Prostate 2012
Plasma concentrations but not serum concentrations of brain-derived neurotrophic factor are related to pro-inflammatory cytokines in patients undergoing major abdominal surgery
G Chimienti, A Mezzapesa, MT Rotelli, L Lupo, G Pepe
Clinical Biochemistry 2012
ASSOCIATION OF TUMOR NECROSIS FACTOR α, INTERLEUKIN 6, AND INTERLEUKIN 10 PROMOTER POLYMORPHISM WITH PROLIFERATIVE DIABETIC RETINOPATHY IN TYPE 2 DIABETIC SUBJECTS:
SK Paine, A Sen, S Choudhuri, LK Mondal, IH Chowdhury, A Basu, A Mukherjee, B Bhattacharya
Retina 2012
Single nucleotide polymorphisms associated with sporadic brain arteriovenous malformations: where do we stand?
CL Sturiale, A Puca, P Sebastiani, I Gatto, A Albanese, CD Rocco, G Maira, R Pola
Brain 2012
Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability
J Yan, JM Greer, PA McCombe
Journal of Neuroimmunology 2012
Association of IL-6 polymorphisms with gastric cancer risk: Evidences from a meta-analysis
W Junli, H Wenjun, L Jinxin, N Legen, W Yesheng, Y Fenglian
Cytokine 2012
IL6 gene polymorphisms and susceptibility to colorectal cancer: a meta-analysis and review
Y Yu, W Wang, S Zhai, S Dang, M Sun
Molecular Biology Reports 2012
Genes, physical fitness and ageing
N Garatachea, A Lucia
Ageing Research Reviews 2012
Comparative analysis of IL6 and IL6 receptor gene polymorphisms in mastocytosis
E Rausz, A Szilágyi, B Nedoszytko, M Lange, M Niedoszytko, O Lautner-Csorba, A Falus, I Aladzsity, M Kokai, P Valent, M Marschalko, B Hidvégi, J Szakonyi, J Csomor, J Várkonyi
British Journal of Haematology 2012
Association of Interleukin-6 Polymorphisms with Obesity and Hyperglycemia in Mexican Adolescents
G Ramírez-López, EP Buen, J Sánchez-Corona, J Salmerón-Castro, F Mendoza-Carrera
Archives of Medical Research 2012
Interleukin-6 gene −174G>C and −636G>C promoter polymorphisms and prostate cancer risk
JF Magalhães, AJ Cortinhas, CM Albuquerque, CS Baptista, R Ribeiro, C Viegas, A Matos, J Machado, MA Pires, H Guedes-Pinto, A Martins-Bessa, JC Leitão, E Bastos
Molecular Biology Reports 2012
A study on the association of TNF-α-308, IL-6-174, IL-10-1082 and IL-1RaVNTR gene polymorphisms with rheumatic heart disease in Pakistani patients
S Rehman, N Akhtar, N Saba, S Munir, W Ahmed, A Mohyuddin, A Khanum
Cytokine 2012
Interleukin-6 Gene Promoter-572 C Allele may Play a Role in Rate of Disease Progression in Multiple Sclerosis
J Yan, J Liu, CY Lin, PA Csurhes, MP Pender, PA McCombe, JM Greer
International journal of molecular sciences 2012
The lack of association between interleukin-6 gene −174 G/C polymorphism and the risk of type 1 diabetes mellitus: A meta-analysis of 18,152 subjects
YW Yin, QQ Sun, BB Zhang, AM Hu, Q Wang, HL Liu, ZZ Hou, YH Zeng, RJ Xu, LB Shi
Gene 2012
Association between interleukin-18 polymorphisms and systemic lupus erythematosus: a meta-analysis
GG Song, SJ Choi, JD Ji, YH Lee
Molecular Biology Reports 2012
-174G/C interleukin-6 gene promoter polymorphism predicts therapeutic response to etanercept in rheumatoid arthritis
I Jančić, N Arsenović-Ranin, M Šefik-Bukilica, S Živojinović, N Damjanov, V Spasovski, S Srzentić, B Stanković, S Pavlović
Rheumatology International 2012
Expression, polymorphism and methylation pattern of interleukin-6 in periodontal tissues
FA Stefani, MB Viana, AC Dupim, JA Brito, RS Gomez, JE da Costa, PR Moreira
Immunobiology 2012
AA Amyloidosis: Mount Sinai Experience, 1997-2012
D Bunker, P Gorevic
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 2012
Genetic predictors of fatigue in prostate cancer patients treated with androgen deprivation therapy: preliminary findings
HS Jim, JY Park, J Permuth-Wey, MA Rincon, KM Phillips, BJ Small, PB Jacobsen
Brain, Behavior, and Immunity 2012
Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study
DS O'Mahony, BJ Glavan, TD Holden, C Fong, RA Black, G Rona, P Tejera, DC Christiani, MM Wurfel
PloS one 2012
Potential of ayurgenomics approach in complex trait research: leads from a pilot study on rheumatoid arthritis
RC Juyal, S Negi, P Wakhode, S Bhat, B Bhat, BK Thelma
PloS one 2012
Interleukin-6 -634 C/G and -174 G/C polymorphisms in Korean patients undergoing hemodialysis
JH Ryu, SJ Kim
The Korean Journal of Internal Medicine 2012
When grief makes you sick: bereavement induced systemic inflammation is a question of genotype
CR Schultze-Florey, O Martínez-Maza, L Magpantay, EC Breen, MR Irwin, H Gündel, MF O'Connor
Brain, Behavior, and Immunity 2012
Evaluation of published single nucleotide polymorphisms associated with acute GVHD
JW Chien, XC Zhang, W Fan, H Wang, LP Zhao, PJ Martin, BE Storer, M Boeckh, EH Warren, JA Hansen
Blood 2012
Prevention of colitis-associated cancer: natural compounds that target the IL-6 soluble receptor
Cate Moriasi, Dharmalingam Subramaniam, Shanjana Awasthi, Satish Ramalingam, Shrikant Anant
Anti-cancer agents in medicinal chemistry 2012
Polymorphisms of −174G>C and −572G>C in the Interleukin 6 (IL-6) Gene and Coronary Heart Disease Risk: A Meta-Analysis of 27 Research Studies
G Zheng, H Chen, SQ Xiong, MP Dubé
PloS one 2012
Is Still's Disease an Autoinflammatory Syndrome?
L Rossi-Semerano, I Koné-Paut
International Journal of Inflammation 2012
The Association of Polymorphisms in Cytokine Genes with Acute Rejection and the Pathogenesis of Hepatitis B and C in Liver Transplant Recipients
R Yaghobi, MH Karimi, M Namayandeh, B Geramizadeh, S Nikeghbalian, SA Malekhosseini, Y Hosseini
Laboratory Medicine 2012
The association between interleukin-6 polymorphisms and systemic lupus erythematosus: a meta-analysis
YH Lee, HS Lee, SJ Choi, JD Ji, GG Song
Lupus 2012
Inflammation and Immune-Related Candidate Gene Associations with Acute Lung Injury Susceptibility and Severity: A Validation Study
DS O'Mahony, BJ Glavan, TD Holden, C Fong, RA Black, G Rona, P Tejera, DC Christiani, MM Wurfel, YG Yao
PloS one 2012
Genetics of leprosy reactions: an overview
V Fava, M Orlova, A Cobat, A Alcaïs, M Mira, E Schurr
Memórias do Instituto Oswaldo Cruz 2012
Efficacy, safety and tolerability of tocilizumab in patients with systemic juvenile idiopathic arthritis
S Yokota, T Tanaka, T Kishimoto
Therapeutic Advances in Musculoskeletal Diseases 2012
Interleukin gene polymorphisms in pneumoconiosis
S Helmig, M Grossmann, J Wübbeling, J Schneider
International journal of molecular medicine 2012
Influence of the IL6 Gene in Susceptibility to Systemic Sclerosis
MC Cénit, CP Simeón, MC Vonk, JL Callejas-Rubio, G Espinosa, P Carreira, FJ Blanco, JA Narvaez, C Tolosa, JA ROMÁN-IVORRA, I Gómez-García, FJ García-Hernández, M Gallego, R García-Portales, MV Egurbide, VI Fonollosa, PA de la PEÑA, FJ López-Longo, MA González-Gay, R Hesselstrand, G Riemekasten, T Witte, AE Voskuyl, AJ Schuerwegh, R Madhok, C Fonseca, C Denton, A Nordin, ØY Palm, JA van LAAR, N Hunzelmann, JH Distler, A Kreuter, A Herrick, J Worthington, BP Koeleman, TR Radstake, JA Martín
The Journal of rheumatology 2012
Immunosenescence
JA Bosch, AC Phillips, J M.
2012
Gene polymorphism and protein of human pro- and anti-inflammatory cytokines in Chinese healthy subjects and chronic periodontitis patients
WT Loo, C Fan, L Bai, Y Yue, Y Dou, M Wang, H Liang, MN Cheung, LW Chow, J Li, Y Tian, L Qing
Journal of Translational Medicine 2012
The association between interleukin-6 polymorphisms and rheumatoid arthritis: a meta-analysis.
Lee YH, Bae SC, Choi SJ, Ji JD, Song GG
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2012
IL6 gene polymorphisms and susceptibility to colorectal cancer: a meta-analysis and review.
Yu Y, Wang W, Zhai S, Dang S, Sun M
Molecular Biology Reports 2012
Influence of IL-6 haplotypes on clinical and inflammatory response in aggressive periodontitis.
Nibali L, Pelekos G, D'Aiuto F, Chaudhary N, Habeeb R, Ready D, Parkar M, Donos N
Clinical Oral Investigations 2012
Interleukin-6 gene -174G>C and -636G>C promoter polymorphisms and prostate cancer risk.
Magalhães JF, Cortinhas AJ, Albuquerque CM, Baptista CS, Ribeiro R, Viegas C, Matos A, Machado J, Pires MA, Guedes-Pinto H, Martins-Bessa A, Leitão JC, Bastos E
Molecular Biology Reports 2012
-174G/C interleukin-6 gene promoter polymorphism predicts therapeutic response to etanercept in rheumatoid arthritis.
Jančić I, Arsenović-Ranin N, Sefik-Bukilica M, Zivojinović S, Damjanov N, Spasovski V, Srzentić S, Stanković B, Pavlović S
Rheumatology International 2012
Association between interleukin-18 polymorphisms and systemic lupus erythematosus: a meta-analysis.
Song GG, Choi SJ, Ji JD, Lee YH
Molecular Biology Reports 2012
Role of cytokine gene (IFN-γ, TNF-α, TGF-β1, IL-6, and IL-10) polymorphisms in pathogenesis of acute rheumatic fever in Turkish children.
Col-Araz N, Pehlivan S, Baspinar O, Oguzkan-Balci S, Sever T, Balat A
European Journal of Pediatrics 2012
PREVENTION OF COLITIS-ASSOCIATED CANCER: NATURAL COMPOUNDS THAT TARGET THE IL-6 SOLUBLE RECEPTOR
Moriasi C, Subramaniam D, Awasthi S, Anant S, Ramalingam S
Anti-cancer agents in medicinal chemistry 2012
Differential Combination of Cytokine and Interferon- γ +874 T/A Polymorphisms Determines Disease Severity in Pulmonary Tuberculosis
A Ansari, Z Hasan, G Dawood, R Hussain
PloS one 2011
Biomarkers in Acute Lung Injury: Insights into the Pathogenesis of Acute Lung Injury
LJ Cross, MA Matthay
Critical Care Clinics 2011
Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review
BH Tan, JA Ross, S Kaasa, F Skorpen, KC Fearon
Journal of Genetics 2011
Studies of gene variants related to inflammation, oxidative stress, dyslipidemia, and obesity: implications for a nutrigenetic approach
ML Curti, P Jacob, MC Borges, MM Rogero, SR Ferreira
Journal of Obesity 2011
Association of haplotypes of inflammation-related genes with gastric preneoplastic lesions in African Americans and Caucasians
J Zabaleta, MC Camargo, MD Ritchie, MB Piazuelo, RA Sierra, SD Turner, A Delgado, ET Fontham, BG Schneider, P Correa, AC Ochoa
International Journal of Cancer 2011
Do Interleukin Polymorphisms Play a Role in the Prevention of Colorectal Adenoma Recurrence by Dietary Flavonols?
G Bobe, G Murphy, PS Albert, LB Sansbury, MR Young, E Lanza, A Schatzkin, NH Colburn, AJ Cross
European Journal of Cancer Prevention 2011
Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions
ED Mellins, C Macaubas, AA Grom
Nature Reviews Rheumatology 2011
Advances in Clinical Chemistry
M Mahler
Advances in Clinical Chemistry Volume 54 2011
Association of IL1A, IL1B, ILRN, IL6, IL10 and TNF-α polymorphisms with risk and clinical course of multiple sclerosis in a Polish population
D Mirowska-Guzel, G Gromadzka, A Mach, A Czlonkowski, A Czlonkowska
Journal of Neuroimmunology 2011
Cytokines
L Cassetta, G Poli, M Alfano
Cytokines 2011
The pathogenesis of oligoarticular/polyarticular vs systemic juvenile idiopathic arthritis
YT Lin, CT Wang, ME Gershwin, BL Chiang
Autoimmunity Reviews 2011
Promoter region polymorphism (−174 G/C) of interleukin-6 gene and SLE; are they associated?
D Abbas, E Hamdy, MM Helal
The Egyptian Rheumatologist 2011
Interleukin 6-174G>C polymorphism and risk of aneurysmal subarachnoid hemorrhage: case-control study and meta-analysis
J Pera, T Dziedzic, M Adamski, J Jagiella, M Krupa, M Moskala, A Szczudlik, A Slowik
Acta Neurologica Scandinavica 2011
Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients
D Lasigliè, E Traggiai, S Federici, M Alessio, A Buoncompagni, A Accogli, S Chiesa, F Penco, A Martini, M Gattorno
PloS one 2011
Interleukin-6 (-636 c/g) gene polymorphism in korean children with kawasaki disease
HM Ahn, IS Park, SJ Hong, YM Hong
Korean Circulation Journal 2011
Functional inflammatory genotypes in ischemic stroke: could we use them to predict age of onset and long-term outcome?
S Marousi, A Antonacopoulou, H Kalofonos, P Papathanasopoulos, M Karakantza, J Ellul
Stroke Research and Treatment 2011
Association of cytokine gene polymorphisms with psoriasis in cases from the nile delta of egypt
AA Settin, HA Hassan, RA El-Baz, TA Hassan
Indian journal of dermatology 2011
Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study
M Emonts, MJ Hazes, JJ Houwing-Duistermaat, CE van der Jongh, L Vogel, HK Han, JM Wouters, JD Laman, RJ Dolhain
BMC Medical Genetics 2011
Disturbed Sleep in Pediatric Patients With Leukemia: The Potential Role of &lt;i&gt;Interleukin-6&lt;/i&gt; (-174GC) and &lt;i&gt;Tumor Necrosis Factor&lt;/i&gt; (-308GA) Polymorphism
K Vallance, J Yang, J Li, VM Crabtree, PS Hinds, BN Mandrell
Oncology Nursing Forum 2011
De novo 19q13.42 duplications involving NLRP gene cluster in a patient with systemic-onset juvenile idiopathic arthritis
H Tadaki, H Saitsu, A Nishimura-Tadaki, T Imagawa, M Kikuchi, R Hara, U Kaneko, T Kishi, T Miyamae, N Miyake, H Doi, Y Tsurusaki, H Sakai, S Yokota, N Matsumoto
Journal of Human Genetics 2011
Exonic deletion of CASP10 in a patient presenting with systemic juvenile idiopathic arthritis, but not with autoimmune lymphoproliferative syndrome type IIa
H Tadaki, H Saitsu, H Kanegane, N Miyake, T Imagawa, M Kikuchi, R Hara, U Kaneko, T Kishi, T Miyamae, A Nishimura, H Doi, Y Tsurusaki, H Sakai, S Yokota, N Matsumoto
International Journal of Immunogenetics 2011
-174G/C interleukin-6 gene polymorphism and the risk of transplanted kidney failure or graft loss during a 5-year follow-up period
M Kocierz, U Siekiera, A Kolonko, H Karkoszka, J Chudek, L Cierpka, A Wiȩcek
Tissue Antigens 2011
IL-6 promoter polymorphism (−174G/C) and systemic lupus erythematosus
E Hamdy, RA Afify, A Kamal, D Abass, M Mahmoud
Comparative Clinical Pathology 2011
An overview on the genetic of rheumatoid arthritis: A never-ending story
C Perricone, F Ceccarelli, G Valesini
Autoimmunity Reviews 2011
MCP-1 −2518 A/G functional polymorphism is associated with increased susceptibility to active pulmonary tuberculosis in Tunisian patients
W Ben-Selma, H Harizi, J Boukadida
Molecular Biology Reports 2011
Genes and the ageing muscle: a review on genetic association studies
N Garatachea, A Lucía
AGE 2011
Association of the IL-6 -174G/C gene polymorphism with knee osteoarthritis in a Thai population
S Honsawek, B Deepaisarnsakul, A Tanavalee, P Yuktanandana, P Bumrungpanichthaworn, S Malila, N Saetan
Genetics and Molecular Research 2011
Interleukin-6 Plasma Levels Are Modulated by a Polymorphism in the NFKB1 Gene and are Associated with Outcome Following Rituximab-Combined Chemotherapy in Diffuse Large B-Cell Non-Hodgkin Lymphoma
M Giachelia, MT Voso, MC Tisi, M Martini, V Bozzoli, G Massini, F D'Alo, LM Larocca, G Leone, S Hohaus
Leukemia and Lymphoma 2011
Update on the pathogenesis and treatment of systemic idiopathic arthritis :
KA Sikora, AA Grom
Current Opinion in Pediatrics 2011
Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance
PC Underwood, B Chamarthi, JS Williams, B Sun, A Vaidya, BA Raby, J Lasky-Su, PN Hopkins, GK Adler, GH Williams
Metabolism 2011
Has dysregulated interleukin-6 gene a role in the development of Alzheimer's disease?
C Capurso
Neuroscience Letters 2011
A study of the impact of cytokine gene polymorphism in acute rejection of renal transplant recipients
MH Karimi, S Daneshmandi, AA Pourfathollah, B Geramizadeh, R Yaghobi, GA Rais-Jalali, J Roozbeh, S Bolandparvaz
Molecular Biology Reports 2011
Associations between inflammatory markers, candidate polymorphisms and physical performance in older Danish twins
K Tiainen, M Thinggaard, M Jylhä, E Bladbjerg, K Christensen, L Christiansen
Experimental Gerontology 2011
Contact lens-related microbial keratitis: how have epidemiology and genetics helped us with pathogenesis and prophylaxis
F Stapleton, N Carnt
Eye 2011
Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African Americans
FT Ayele, A Doumatey, H Huang, J Zhou, B Charles, M Erdos, J Adeleye, W Balogun, O Fasanmade, T Johnson, J Oli, G Okafor, A Amoah, BA Eghan, K Agyenim-Boateng, J Acheampong, CA Adebamowo, A Herbert, N Gerry, M Christman, G Chen, D Shriner, A Adeyemo, CN Rotimi
Immunogenetics 2011
Interleukin-6 −174G/C polymorphism and the risk of Alzheimer's disease in Caucasians: A meta-analysis
XM Han, CH Wang, X Sima, SY Liu
Neuroscience Letters 2011
Effects of the interleukin-6 (IL-6) polymorphism on toxic metal and trace element levels in placental tissues
Z Kayaaltı, D Tekin, V Aliyev, S Yalçın, G Kurtay, T Söylemezoğlu
Science of The Total Environment 2011
Association of interleukin-6-572G/C gene polymorphisms in the Cantonese population with intracranial aneurysms
G Zhang, Y Tu, W Feng, L Huang, M Li, S Qi
Journal of the Neurological Sciences 2011
SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS
FD Benedetti, R Schneider
Textbook of Pediatric Rheumatology 2011
Association of plasma IL-6 and soluble IL-6 receptor levels with the Asp358Ala polymorphism of the IL-6 receptor gene in schizophrenic patients
D Sasayama, C Wakabayashi, H Hori, T Teraishi, K Hattori, M Ota, M Ishikawa, K Arima, T Higuchi, N Amano, H Kunugi
Journal of Psychiatric Research 2011
The role of interleukin DNA polymorphisms in gastric cancer
A Yuzhalin
Human Immunology 2011
Association of IL-1β and IL-6 gene polymorphisms with recurrent spontaneous abortion in a Chinese Han population : IL-1β and IL-6 gene polymorphisms in Chinese RSA
X Ma, LJ Xu, J Wang, MM Xian, M Liu
International Journal of Immunogenetics 2011
Gene–PUFA interactions and obesity risk
C Jourdan, S Kloiber, A Nieters, H Seiler, H Himmerich, MA Kohli, S Lucae, G Wolfram, C Gieger, HE Wichmann, J Linseisen
British Journal of Nutrition 2011
Association between IL-6 –174G/C polymorphism and acute rejection of renal allograft: Evidence from a meta-analysis
R Lv, X Hu, Y Bai, H Long, L Xu, Z Liu, X Li, H Huang, L Wang, B Ying
Transplant Immunology 2011
Investigation of TNF-alpha, TGF-beta 1, IL-10, IL-6, IFN-gamma, MBL, GPIA, and IL1A gene polymorphisms in patients with idiopathic thrombocytopenic purpura
M Pehlivan, V Okan, T Sever, SO Balci, M Yilmaz, T Babacan, S Pehlıvan
Platelets 2011
Interleukin-6 in oral diseases: a review : IL-6 and oral diseases
L Nibali, S Fedele, F D’Aiuto, N Donos
Oral Diseases 2011
Association between the Interleukin-6 Promoter Polymorphism −174G/C and Serum Lipoprotein(a) Concentrations in Humans
HK Berthold, M Laudes, W Krone, I Gouni-Berthold
PloS one 2011
Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis
F Ceccarelli, C Perricone, M Fabris, C Alessandri, A Iagnocco, C Fabro, E Pontarini, SD Vita, G Valesini
Arthritis Research & Therapy 2011
Les applications en rhumatologie: en génomique
P Dieudé, HJ Garchon
Revue du Rhumatisme 2011
Relationship between the levels of serum high-sensitivity C-reactive protein and interleukin-6 and interleukin-6 gene polymorphisms in type 2 diabetes mellitus
DF Elgayar, SH Aboulsoud
Comparative Clinical Pathology 2011
IL-6 −174 C/C Genotype Is Not Conclusively a Low IL-6 Production Phenotype
J Nokso-Koivisto, JA Patel, T Chonmaitree
The Journal of Infectious Diseases 2011
Tumour Necrosis Factor Gene Polymorphism and Disease Prevalence : TNF Gene Polymorphism and Disease Prevalence
T Qidwai, F Khan
Scandinavian Journal of Immunology 2011
Genetic variations in multiple myeloma I: effect on risk of multiple myeloma : SNP and risk of multiple myeloma patients
A Vangsted, TW Klausen, U Vogel
European Journal of Haematology 2011
Insulin-like growth factor 1 receptor polymorphism rs2229765 and circulating interleukin-6 level affect male longevity in a population-based prospective study (Treviso Longeva− TRELONG)
D Albani, S Mazzuco, L Polito, S Batelli, G Biella, F Ongaro, DR Gustafson, P Antuono, G Gajo, E Durante, L Caberlotto, A Zanardo, M Siculi, M Gallucci, G Forloni
The Aging Male 2011
Association of tumor necrosis factor β genetic polymorphism and sepsis susceptibility
F Delongui, CM Grion, MA Watanabe, HK Morimoto, AM Bonametti, JM Oda, AP Kallaur, T Matsuo, EM Reiche
Experimental and therapeutic medicine 2011
Mendelian Randomization Study of Interleukin-6 in Chronic Obstructive Pulmonary Disease
YM van Durme, L Lahousse, KM Verhamme, L Stolk, M Eijgelsheim, DW Loth, AG Uitterlinden, MM Breteler, GF Joos, A Hofman, BH Stricker, GG Brusselle
Respiration 2011
Pediatric Coronary Allograft Vasculopathy-A Review of Pathogenesis and Risk Factors : Pediatric CAV Pathogenesis
KR Schumacher, RJ Gajarski, S Urschel
Congenital Heart Disease 2011
Genetic predisposition to respiratory infection and sepsis
LP Chung, GW Waterer
Critical Reviews in Clinical Laboratory Sciences 2011
Cytokine gene polymorphism and asthma susceptibility, progress and control level
S Daneshmandi, AA Pourfathollah, Z Pourpak, H Heidarnazhad, PA Kalvanagh
Molecular Biology Reports 2011
The association of genetic polymorphisms with cerebral palsy: a meta-analysis : Association of Genetic Polymorphisms with CP
D Wu, YF Zou, XY Xu, XL Feng, L Yang, GC Zhang, XS Bu, JL Tang
Developmental Medicine & Child Neurology 2011
Blastocystis infection is associated with irritable bowel syndrome in a Mexican patient population
DE Jimenez-Gonzalez, WA Martinez-Flores, J Reyes-Gordillo, ME Ramirez-Miranda, S Arroyo-Escalante, M Romero-Valdovinos, D Stark, V Souza-Saldivar, F Martinez-Hernandez, A Flisser, A Olivo-Diaz, P Maravilla
Parasitology Research 2011
Body composition changes after laparoscopic adjustable gastric banding: what is the role of −174G&gt;C interleukin-6 promoter gene polymorphism in the therapeutic strategy?
LD Renzo, MG Carbonelli, A Bianchi, L Iacopino, R Fiorito, ND Daniele, AD Lorenzo
International Journal of Obesity 2011
Harper's Textbook of Pediatric Dermatology: Irvine/Harper's Textbook of Pediatric Dermatology
R Happle
Harper's Textbook of Pediatric Dermatology: Irvine/Harper's Textbook of Pediatric Dermatology 2011
Impact of interleukin-6 promoter polymorphism and serum interleukin-6 level on the acute inflammation and neovascularization stages of patients with Eales’ disease
A Sen, SK Paine, IH Chowdhury, A Mukherjee, S Choudhuri, A Saha, LK Mandal, B Bhattacharya
Molecular vision 2011
Polymorphisms in interleukin-6-6331 influences the susceptibility of a Chinese population to gastric cancer
J Yu, Y Jia, KF Cheung, Z Zeng, L Tian, S Wang, P Hu, JJ Sung
Cancer Investigation 2011
Distributions of interleukin-6 (IL-6) promoter and metallothionein 2A (MT2A) core promoter region gene polymorphisms and their associations with aging in Turkish population
Z Kayaaltı, L Şahiner, ME Durakoğlugil, T Söylemezoğlu
Archives of Gerontology and Geriatrics 2011
A polymorphism linked to elevated levels of interferon-γ is associated with an increased risk of cytomegalovirus disease among Caucasian lung transplant recipients at a single center
D Mitsani, MH Nguyen, DM Girnita, K Spichty, EJ Kwak, FP Silveira, Y Toyoda, JM Pilewski, M Crespo, JK Bhama, R Abdel-Massih, D Zaldonis, A Zeevi, CJ Clancy
The Journal of Heart and Lung Transplantation 2011
Gender differences in the IL6 -174G>C and ESR2 1730G>A polymorphisms and the risk of Parkinson's disease
MS Luciano, L Ozelius, RB Lipton, D Raymond, SB Bressman, R Saunders-Pullman
Neuroscience Letters 2011
Antagonistic pleiotropy at the human IL6 promoter confers genetic resilience to the pro-inflammatory effects of adverse social conditions in adolescence
SW Cole, JM Arevalo, K Manu, EH Telzer, L Kiang, JE Bower, MR Irwin, AJ Fuligni
Developmental Psychology 2011
Repeated course antenatal steroids, inflammation gene polymorphisms, and neurodevelopmental outcomes at age 2
EA Clark, L Mele, RJ Wapner, CY Spong, Y Sorokin, A Peaceman, JD Iams, KJ Leveno, M Harper, SN Caritis, BM Mercer, JM Thorp, SM Ramin, M Carpenter, DJ Rouse,
American Journal of Obstetrics and Gynecology 2011
Cytokine gene polymorphisms and length of gestation
M Harper, SL Zheng, E Thom, MA Klebanoff, J Thorp, Y Sorokin, MW Varner, JD Iams, M Dinsmoor, BM Mercer, DJ Rouse, SM Ramin, GD Anderson,
Obstetrics and gynecology 2011
Comparative insights into the regulation of inflammation: Levels and predictors of interleukin 6 and interleukin 10 in young adults in the Philippines
TW McDade, PS Tallman, LS Adair, B Judith, CW Kuzawa
American Journal of Physical Anthropology 2011
Inflammation and Genetics: An Insight in the Centenarian Model
T Iannitti, B Palmieri
Human Biology 2011
The Interleukin-6 Gene Promoter Polymorphism -174 and Atherosclerotic Events in Overweight Transplanted Patients
J Bamoulid, C Courivaud, M Deschamps, B Gaugler, P Tiberghien, JM Chalopin, P Saas, D Ducloux
Journal of Transplantation 2011
The Interleukin-6 Promoter −597/−572/−174 Genotype Does Not Affect Interleukin-6 Production in Hemodialysis Patients
F Schulte, P Schnülle, P Bugert, H Klüter, M Müller-Steinhardt
Journal of Interferon & Cytokine Research 2011
Association Study of BMP4, IL6, Leptin, MMP3, and MTNR1B Gene Promoter Polymorphisms and Adolescent Idiopathic Scoliosis:
M Mórocz, Á Czibula, ZB Grózer, A Szécsényi, PZ Álmos, I Raskó, T Illés
Spine 2011
IL-6 polymorphism associated with fatal outcome in patients with severe traumatic brain injury
AL Libera, A Regner, J Paoli, L Centenaro, TT Martins, D Simon
Brain Injury 2011
Genetic and Environmental Influences on the Plasma Interleukin-6 Concentration in Patients with a Recent Myocardial Infarction: A Case–Control Study
M Bennermo, M Nordin, P Lundman, S Boqvist, C Held, A Samnegård, CG Ericsson, A Silveira, A Hamsten, MM Nastase, P Tornvall
Journal of Interferon & Cytokine Research 2011
Interleukin-6 −174 G/C Promoter Polymorphism is Associated with Persistence of Chlamydia pneumoniae Antibodies in Young Men: IL-6 -174G/C SNP and C. pneumoniae
A Rantala, T Lajunen, R Juvonen, M Paldanius, S Silvennoinen-Kassinen, A Peitso, O Vainio, M Leinonen, P Saikku
Scandinavian Journal of Immunology 2011
IL-1 cluster gene polymorphisms in Turkish patients with Behçet’s disease: IL-1 cluster gene polymorphisms in BD
AA Özçimen, K Dilek, Ü Bingöl, H Sarıcaoğlu, A Sarandöl, Ö Taşkapılıoğlu, M Yurtkuran, MA Yurtkuran, HB Oral
International Journal of Immunogenetics 2011
The G to A polymorphism at -597 of the interleukin-6 gene is extremely rare in southern Han Chinese
SP Gao, M Pan, C Chen, LJ Ge, MH Jiang, H Luan, JG Zheng, XT Deng, HY Pan, JH Zhu
Cytokine 2011
Association of IL-6 and IL-6R gene polymorphisms with susceptibility to respiratory tract infections in young Finnish men
A Rantala, T Lajunen, R Juvonen, S Silvennoinen-Kassinen, A Peitso, O Vainio, P Saikku, M Leinonen
Human Immunology 2011
Lack of an association between interleukin-6 gene promoter polymorphisms (−174G/C, −572G/C) and ischemic heart disease and/or ischemic stroke: A meta-analysis
Y Ma, RK Tang, X Yang, GG Peng, Y Liu, XM Wang, BH Wu, JM Yu
Human Immunology 2011
Detection and characterization of interleukin-6 gene variants in Canis familiaris: Association studies with periodontal disease
F Morinha, C Albuquerque, J Requicha, I Dias, J Leitão, I Gut, H Guedes-Pinto, C Viegas, E Bastos
Gene 2011
Cytokine gene polymorphism in microscopic colitis association with the IL-6-174 GG genotype:
RM Koskela, TJ Karttunen, SE Niemelä, JK Lehtola, RS Bloigu, RA Karttunen
European Journal of Gastroenterology & Hepatology 2011
Interleukin-4 Gene Polymorphisms Confer Behçet’s Disease in Turkish Population: IL-4 Gene Polymorphisms Confer BD
HB Oral, K Dilek, AA Özçimen, Ö Taşkapılıoğlu, Ü Bingöl, A Sarandöl, H Sarıcaoğlu, M Yurtkuran, MA Yurtkuran
Scandinavian Journal of Immunology 2011
The role of IL-6, IL-8 and MCP-1 and their promoter polymorphisms IL-6 -174GC, IL-8 -251AT and MCP-1 -2518AG in the risk of venous thromboembolism: A case-control study
MF Matos, DM Lourenço, CM Orikaza, JA Bajerl, MA Noguti, VM Morelli
Thrombosis Research 2011
Modelling epistasis in genetic disease using Petri nets, evolutionary computation and frequent itemset mining
M Mayo, L Beretta
Expert Systems with Applications 2011
Role of Inflammation-Related Gene Polymorphisms in Patients with Central Retinal Vein Occlusion
R Maier, I Steinbrugger, A Haas, M Selimovic, W Renner, Y El-Shabrawi, C Werner, A Wedrich, O Schmut, M Weger
Ophthalmology 2011
The Presence of Functionally Relevant Toll-Like Receptor Polymorphisms Does Not Significantly Correlate with Development or Outcome of Sepsis
P Ahmad-Nejad, C Denz, W Zimmer, J Wacker, P Bugert, C Weiss, M Quintel, M Neumaier
Genetic Testing and Molecular Biomarkers 2011
Role of interleukin-6 −174 G/C promoter polymorphism in trace metal levels of autopsy kidney and liver tissues
S Yalçın, Z Kayaaltı, T Söylemezoğlu
International Journal of Hygiene and Environmental Health 2011
Possible effect of gene polymorphisms on the release of TNFα and IL1 cytokines in coal workers’ pneumoconiosis
I Ates, B Yucesoy, A Yucel, SH Suzen, Y Karakas, A Karakaya
Experimental and Toxicologic Pathology 2011
Tumor necrosis factor-α and interleukin-6 expression in leukocytes and their association with polymorphisms and bone markers in diabetic individuals treated with pioglitazone
ST Himelfarb, FA Silva, SS Arazi, CM Farjado, A Garofalo, MC Bertolami, A Bertolami, A Faludi, MF Sampaio, AA Rezende, RD Hirata, MH Hirata
Drug Metabolism and Drug Interactions 2011
Genetic Variations in the Interleukin-6 and Interleukin-8 Genes and the Interleukin-6 Receptor Gene in Delirium
BC van Munster, AH Zwinderman, SE de Rooij
Rejuvenation Research 2011
Lack of association between IL-1 and IL-6 gene polymorphisms and myocardial infarction in Turkish population: Lack of association between IL-1 and IL-6 gene polymorphisms
A Coker, A Arman, O Soylu, T Tezel, A Yildirim
International Journal of Immunogenetics 2011
Factors related to disability: Evidence from the “Treviso Longeva (TRELONG) Study”
M Gallucci, F Ongaro, S Meggiolaro, P Antuono, DR Gustafson, GL Forloni, D Albani, GB Gajo, E Durante, L Caberlotto, A Zanardo, M Siculi, G Muffato, C Regini
Archives of Gerontology and Geriatrics 2011
Interleukin-1β and Interleukin-6 Expression and Gene Polymorphisms in Subjects with Peri-Implant Disease: Interleukin-1β and Interleukin-6 Expression and Gene Polymorphisms in Subjects with Peri-Implant Disease
RF Melo, BM Lopes, JA Shibli, E Marcantonio, RA Marcantonio, GM Galli
Clinical Implant Dentistry and Related Research 2011
Looking at paediatric rheumatology over the past 50 years
P Woo, RE Petty
Rheumatology 2011
Association of cytokine gene alleles with the inflammation of human periodontal tissue
AV Safonova, AN Petrin, SD Arutyunov, VN Tsarev, LA Akulenko, AO Zorina, DV Rebrikov, AV Rubanovich, SA Borinskaya, NK Yankovsky
Acta Naturae 2011
Association of Interleukin-6 Gene Polymorphism With Angina Pectoris
FG Amorim, BP Campagnaro, CL Tonini, AP Norbim, ID Louro, EC Vasquez, JA Arruda, SS Meyrelles
Angiology 2011
Role of IL-1 Beta in the Development of Human TH17 Cells: Lesson from NLPR3 Mutated Patients
D Lasigliè, E Traggiai, S Federici, M Alessio, A Buoncompagni, A Accogli, S Chiesa, F Penco, A Martini, M Gattorno, JE Khoury
PloS one 2011
Functional Inflammatory Genotypes in Ischemic Stroke: Could We Use Them to Predict Age of Onset and Long-Term Outcome?
S Marousi, A Antonacopoulou, H Kalofonos, P Papathanasopoulos, M Karakantza, J Ellul
Stroke Research and Treatment 2011
Association between variable number tandem repeats within the 3′ flanking region of the interleukin-6 gene and systemic lupus erythematosus in Korean patients
JY Jeon, HA Kim, SH Kim, CH Suh
Lupus 2011
Differential Combination of Cytokine and Interferon- γ +874 T/A Polymorphisms Determines Disease Severity in Pulmonary Tuberculosis
A Ansari, Z Hasan, G Dawood, R Hussain, MM Heimesaat
PloS one 2011
Exercício físico como fator de prevenção aos processos inflamatórios decorrentes do envelhecimento
CJ Brito, AC Volp, OT Nóbrega, FL Júnior, EL Mendes, AF Roas, JF Barros, C Córdova
MOTRIZ 2011
Effects of 174 G/C polymorphism in the promoter region of the interleukin-6 gene on plasma IL-6 levels and muscle strength in elderly women
DS Pereira, DM Garcia, FM Narciso, ML Santos, JM Dias, BZ Queiroz, ER Souza, OT Nóbrega, LS Pereira
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] 2011
IL-10 gene promoter polymorphisms and leprosy in a Colombian population sample
N Cardona-Castro, M Sánchez-Jiménez, W Rojas, G Bedoya-Berrío
Biomédica 2011
HIV and Liver Disease
KE Sherman
2011
Cytokine gene polymorphism and asthma susceptibility, progress and control level.
Daneshmandi S, Pourfathollah AA, Pourpak Z, Heidarnazhad H, Kalvanagh PA
Molecular Biology Reports 2011
Tumour necrosis factor gene polymorphism and disease prevalence.
Qidwai T, Khan F
Scandinavian Journal of Immunology 2011
Blastocystis infection is associated with irritable bowel syndrome in a Mexican patient population.
Jimenez-Gonzalez DE, Martinez-Flores WA, Reyes-Gordillo J, Ramirez-Miranda ME, Arroyo-Escalante S, Romero-Valdovinos M, Stark D, Souza-Saldivar V, Martinez-Hernandez F, Flisser A, Olivo-Diaz A, Maravilla P
Parasitology Research 2011
Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation
K Kawane, H Tanaka, Y Kitahara, S Shimaoka, S Nagata
Proceedings of the National Academy of Sciences 2010
Failure of interferon gamma to induce the anti-inflammatory interleukin 18 binding protein in familial hemophagocytosis
CA Nold-Petry, T Lehrnbecher, A Jarisch, D Schwabe, JM Pfeilschifter, H Muhl, MF Nold
PloS one 2010
Interleukin-6-174 G/C Polymorphism is Not Associated with IL-6 Expression and Susceptibility to Sporadic Colon Cancer
T Čačev, M Jokić, B Lončar, Š Križanac, S Kapitanović
DNA and Cell Biology 2010
Association between interleukin-6 polymorphisms and periodontitis in Indian non-smokers
F Franch-Chillida, L Nibali, I Madden, N Donos, P Brett
Journal of Clinical Periodontology 2010
The interleukin 6 -174 C/C genotype predicts greater rhinovirus illness
WJ Doyle, ML Casselbrant, HS Li-Korotky, AP Doyle, CY Lo, R Turner, S Cohen
The Journal of Infectious Diseases 2010
Gene polymorphisms in chronic periodontitis
ML Laine, BG Loos, W Crielaard
International journal of dentistry 2010
Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer
M Sugimoto, Y Yamaoka, T Furuta
World journal of gastroenterology : WJG 2010
Computational identification of gene-social environment interaction at the human IL6 locus
SW Cole, JM Arevalo, R Takahashi, EK Sloan, SK Lutgendorf, AK Sood, JF Sheridan, TE Seeman
Proceedings of the National Academy of Sciences 2010
Commonly studied polymorphisms in inflammatory cytokine genes show only minor effects on mortality and related risk factors in nonagenarians
S Dato, KS Krabbe, M Thinggaard, BK Pedersen, K Christensen, H Bruunsgaard, L Christiansen
The journals of gerontology. Series A, Biological sciences and medical sciences 2010
Interaction between fibrinogen and IL-6 genetic variants and associations with cardiovascular disease risk in the Cardiovascular Health Study
CL Carty, P Heagerty, SR Heckbert, GP Jarvik, LA Lange, M Cushman, RP Tracy, AP Reiner
Annals of Human Genetics 2010
Activation of JAK-STAT and nitric oxide signaling as a mechanism for donor heart dysfunction
CF Bulcao, KM D'Souza, R Malhotra, M Staron, JY Duffy, PK Pandalai, V Jeevanandam, SA Akhter
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2010
Tocilizumab: The evidence for its place in the treatment of juvenile idiopathic arthritis
T Herlin
Core evidence 2010
Interleukin-6 promoter polymorphism (-174 G/C) in Indian patients with chronic periodontitis
NB Kalburgi, A Bhatia, S Bilichodmath, SR Patil, SB Mangalekar, K Bhat
Journal of Oral Science 2010
Viral hepatitis: Human genes that limit infection
F Grünhage, J Nattermann
Best Practice & Research Clinical Gastroenterology 2010
Gene-gene interaction in regulatory T–cell function in atopy and asthma development in childhood
RW Bottema, M Kerkhof, NE Reijmerink, C Thijs, HA Smit, CP van Schayck, B Brunekreef, AJ van Oosterhout, DS Postma, GH Koppelman
Journal of Allergy and Clinical Immunology 2010
Influence of CRP, IL6, and TNFA Gene Polymorphisms on Circulating Levels of C-Reactive Protein in Mexican Adolescents
F Mendoza-Carrera, G Ramírez-López, NA Ayala-Martínez, AG García-Zapién, SE Flores-Martínez, J Sánchez-Corona
Archives of Medical Research 2010
Genetic Risk Factors for Post-Infectious Irritable Bowel Syndrome Following a Waterborne Outbreak of Gastroenteritis
AC Villani, M Lemire, M Thabane, A Belisle, G Geneau, AX Garg, WF Clark, P Moayyedi, SM Collins, D Franchimont, JK Marshall
Gastroenterology 2010
A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis
AM Valdes, NK Arden, A Tamm, K Kisand, S Doherty, E Pola, C Cooper, A Tamm, KR Muir, I Kerna, D Hart, F O'Neil, W Zhang, TD Spector, RA Maciewicz, M Doherty
Osteoarthritis and Cartilage 2010
A 3-factor epistatic model predicts digital ulcers in Italian scleroderma patients
L Beretta, A Santaniello, M Mayo, F Cappiello, M Marchini, R Scorza
European Journal of Internal Medicine 2010
Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism
MM Beckers, HJ Ruven, FJ Haas, PA Doevendans, H Cate, MH Prins, DH Biesma
European Journal of Internal Medicine 2010
The −174 G/C polymorphism of the IL6 gene is associated with elite power performance
JR Ruiz, A Buxens, M Artieda, D Arteta, C Santiago, G Rodríguez-Romo, JI Lao, F Gómez-Gallego, A Lucia
Journal of Science and Medicine in Sport 2010
Genetic polymorphisms of interleukin-6 modulate fibrosis progression in mild chronic hepatitis C
E Falleti, C Fabris, C Vandelli, C Colletta, A Cussigh, C Smirne, E Fontanini, S Cmet, R Minisini, D Bitetto, P Toniutto, M Pirisi
Human Immunology 2010
EPOC: inflamación bronquial y sistémica
CC Macario, JP de Tajes, EC Lanus
Archivos de Bronconeumología 2010
TNF-α −308G&gt;A and IL-6 −174G&gt;C polymorphisms in Tunisian patients with coronary artery disease
L Ghazouani, SB Khalifa, N Abboud, KB Hamda, AB Khalfallah, N Brahim, WY Almawi, T Mahjoub
Clinical Biochemistry 2010
Preliminary Evidence of an Association Between a Functional IL6 Polymorphism and Fatigue and Sleep Disturbance in Oncology Patients and Their Family Caregivers
C Miaskowski, M Dodd, K Lee, C West, SM Paul, BA Cooper, W Wara, PS Swift, LB Dunn, BE Aouizerat
Journal of Pain and Symptom Management 2010
Combined Effect of Inflammatory Gene Polymorphisms and the Risk of Ischemic Stroke in a Prospective Cohort of Subjects With Type 2 Diabetes: A Go-DARTS Study
CN Palmer, CH Kimber, AS Doney, AS Proia, AD Morris, E Gaetani, M Quarta, RC Smith, R Pola
Diabetes 2010
The interleukin-6 gene −572C/G promoter polymorphism modifies Alzheimer's risk in APOE ɛ4 carriers
M Wang, J Jia
Neuroscience Letters 2010
Pharmaceutical Sciences Encyclopedia: Drug Discovery, Development, and Manufacturing
CD Davis, UM Hanumegowda
Pharmaceutical Sciences Encyclopedia: Drug Discovery, Development, and Manufacturing 2010
Interleukin 6–174 G/C promoter and variable number of tandem repeats (VNTR) gene polymorphisms in sporadic Alzheimer's disease
C Capurso, V Solfrizzi, AM Colacicco, A D'Introno, V Frisardi, BP Imbimbo, M Lorusso, G Vendemiale, M Denitto, A Santamato, D Seripa, A Pilotto, P Fiore, A Capurso, F Panza
Progress in Neuro-Psychopharmacology and Biological Psychiatry 2010
The association of IL-1β, IL-2, and IL-6 gene polymorphisms with bone mineral density and osteoporosis in postmenopausal women
B Czerny, A Kaminski, M Kurzawski, D Kotrych, K Safranow, V Dziedziejko, A Bohatyrewicz, A Pawlik
European Journal of Obstetrics & Gynecology and Reproductive Biology 2010
Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced interleukin-6 secretion
MS Shey, AK Randhawa, M Bowmaker, E Smith, TJ Scriba, M Kock, H Mahomed, G Hussey, TR Hawn, WA Hanekom
Genes and Immunity 2010
Association between lymphotoxin-α (tumor necrosis factor-β) intron polymorphism and predisposition to severe sepsis is modified by gender and age:
E Watanabe, TG Buchman, H Hirasawa, BA Zehnbauer
Critical Care Medicine 2010
Interleukin-6 gene polymorphism in Iranian patients with systemic lupus erythematosus
EM Godarzi, EK Sarvestani, E Aflaki, Z Amirghofran
Clinical Rheumatology 2010
Inflammatory genetic markers of prostate cancer risk
EA Tindall, VM Hayes, DC Petersen
Cancers 2010
Graves’ disease and gene polymorphism of TNF-α, IL-2, IL-6, IL-12, and IFN-γ
M Anvari, O Khalilzadeh, A Esteghamati, F Momen-Heravi, M Mahmoudi, SA Esfahani, A Rashidi, A Amirzargar
Endocrine 2010
Asociación entre el polimorfismo genético de la interleucina-1β (3953 T/C) y la hernia discal lumbar sintomática
JP Aparicio, EL Fernández, HM Prieto, JP Vázquez, IF Bances, VF Henriksen, PL Fernández, JC Menéndez, EV Garay, VA Álvarez
Revista Espa&#xF1;ola de Cirug&#xED;a Ortop&#xE9;dica y Traumatolog&#xED;a 2010
Linkage and association of proinflammatory cytokines genes IL-6, IFNG and TNF with multiple sclerosis
OY Makarycheva, EY Tsareva, MA Sudomoina, OG Kulakova, OV Bykova, NV Gol’tsova, LM Kuzenkova, AN Boiko, OO Favorova
Molecular Biology 2010
Is the −174 C/G polymorphism of the IL6 gene associated with elite power performance? A replication study with two different Caucasian cohorts: −174 C/G Polymorphism and sports performance
N Eynon, JR Ruiz, Y Meckel, C Santiago, C Fiuza-Luces, F Gómez-Gallego, J Oliveira, A Lucia
Experimental Physiology 2010
Influence of IL1B polymorphism on CpG island hypermethylation in Helicobacter pylori-infected gastric cancer
EJ Yoo, SY Park, NY Cho, N Kim, HS Lee, D Kim, GH Kang
Virchows Archiv 2010
Association of cytokine genetic polymorphisms with the humoral immune response to recombinant vaccine against HBV in infants
LC Macedo, AP Isolani, JE Visentainer, RA Moliterno
Journal of Medical Virology 2010
Maternal interleukin-6 (−174) C/C polymorphism is associated with chorioamnionitis and cystic periventricular leucomalacia of the preterm infant
B Resch, A Radinger, C Mannhalter, B Horvath, A Binder, W Zenz, W Walcher, J Haas, WD Müller, B Pertl
Journal of Perinatology 2010
Lack of association between IL-6 −174G/C gene polymorphism and Chagas disease
OA Torres, JE Calzada, Y Beraún, CA Morillo, A González, CI González, J Martín
Tissue Antigens 2010
A Mediterranean diet rich in virgin olive oil may reverse the effects of the -174G/C IL6 gene variant on 3-year body weight change
C Razquin, JA Martinez, MA Martinez-Gonzalez, J Fernández-Crehuet, JM Santos, A Marti
Molecular Nutrition & Food Research 2010
Association of genetic polymorphisms and risk of late post-transplantation infection in pediatric heart recipients
EL Ohmann, MM Brooks, SA Webber, DM Girnita, RE Ferrell, GJ Burckart, R Chinnock, C Canter, L Addonizio, D Bernstein, JK Kirklin, DC Naftel, A Zeevi
The Journal of Heart and Lung Transplantation 2010
Analysis of cytokine genes polymorphism as markers for inhibitor development in haemophilia A
D Chaves, A Belisário, G Castro, M Santoro, C Rodrigues
International Journal of Immunogenetics 2010
Tumor necrosis factor α, interleukin-6 and interleukin-10 polymorphisms in preeclampsia
P Vural, S Degirmencioglu, NY Saral, A Demirkan, C Akgul, G Yildirim, H Issever, H Eroglu
Journal of Obstetrics and Gynaecology Research 2010
The association of functional polymorphisms of IL-6 gene promoter with ischemic stroke: Analysis in two Chinese populations
Y Tong, Z Wang, Y Geng, J Liu, R Zhang, Q Lin, X Li, D Huang, S Gao, D Hu, Y Li, J Cheng, Z Lu
Biochemical and Biophysical Research Communications 2010
The IL-6 −174G/C polymorphism and renal scarring in children with first acute pyelonephritis
B Spasojević-Dimitrijeva, M Živković, A Stanković, L Stojković, M Kostić
Pediatric Nephrology 2010
Interleukin-6 gene –174 C/G and apolipoprotein E gene polymorphisms and the risk of Alzheimer disease in a Polish population
A Klimkowicz-Mrowiec, P Wotkow, K Spisak, A Maruszak, M Styczyńska, M Barcikowska, A Szczudlik, A Słowik
Neurologia i Neurochirurgia Polska 2010
IL-6 SNP diversity among four ethnic groups as revealed by bead-based liquid array profiling: IL-6 SNP diversity among four ethnic groups
M Ivanova, J Ruiqing, S Kawai, M Matsushita, N Ochiai, E Maruya, H Saji
International Journal of Immunogenetics 2010
Interleukin-6 and interleukin-10 gene polymorphism, endothelial dysfunction, and postoperative prognosis in patients with peripheral arterial disease
AL Stoica, E Stoica, I Constantinescu, V Uscatescu, C Ginghina
Journal of Vascular Surgery 2010
Sex-specific effects of CNTF, IL6 and UCP2 polymorphisms on weight gain
AG Heidema, P Wang, CT van Rossum, EJ Feskens, JM Boer, FG Bouwman, P Veer, EC Mariman
Physiology & Behavior 2010
Association between the genetic polymorphism of interleukin-1ß (3953 T/C) and symptomatic lumbar herniated disc
JP Aparicio, EL Fernández, HM Prieto, JP Vázquez, IF Bances, VF Henriksen, PL Fernández, JC Menéndez, EV Garay, VA Álvarez
Revista Española de Cirugía Ortopédica y Traumatología (English Edition) 2010
Lack of Association Between the Promoter Polymorphisms of MMP-3 and IL-6 Genes and Adolescent Idiopathic Scoliosis: A Case-Control Study in a Chinese Han Population
Z Liu, NL Tang, XB Cao, WJ Liu, XS Qiu, JC Cheng, Y Qiu
Spine 2010
Association Between Interleukin-6 −174 Polymorphism and Aggregatibacter actinomycetemcomitans in Chronic Periodontitis
L Nibali, N Donos, S Farrell, D Ready, J Pratten, YK Tu, F D'Aiuto
Journal of Periodontology 2010
The genetics of sporadic ruptured and unruptured intracranial aneurysms: a genetic meta-analysis of 8 genes and 13 polymorphisms in approximately 20,000 individuals: Clinical article
P McColgan, KZ Thant, P Sharma
Journal of Neurosurgery 2010
Graft Inflammation and Histologic Indicators of Kidney Chronic Allograft Failure: Low-Expressing Interleukin-10 Genotypes Cannot Be Ignored:
F Khan, A Sar, I Gonul, H Benediktsson, J Doulla, S Yilmaz, N Berka
Transplantation 2010
Endogenous bacterial flora in pregnant women and the influence of maternal genetic variation: Genital tract microflora in pregnancy and gene polymorphisms
MR Genc, A Onderdonk
BJOG: An International Journal of Obstetrics & Gynaecology 2010
Association of IL-6 promoter and IFN-γ gene polymorphisms with acute rejection of liver transplantation
MH Karimi, S Daneshmandi, AA Pourfathollah, B Geramizadeh, SA Malekhosseini, S Nikeghbalian, R Yaghobi, S Bolandparvaz
Molecular Biology Reports 2010
Patient-tailored therapy in rheumatoid arthritis: an editorial review:
HU Scherer, T Dörner, GR Burmester
Current Opinion in Rheumatology 2010
Cytokine Genetic Polymorphisms and Susceptibility to Kawasaki Disease in Taiwanese Children
KP Weng, TY Ho, YH Chiao, JT Cheng, KS Hsieh, SH Huang, SF Ou, KH Liu, CJ Hsu, PJ Lu, M Hsiao, LP Ger
Circulation journal : official journal of the Japanese Circulation Society 2010
IL-6 −174G>C polymorphism and cancer risk: a meta-analysis involving 29,377 cases and 37,739 controls
B Xu, XB Niu, ZD Wang, W Cheng, N Tong, YY Mi, ZC Min, J Tao, PC Li, W Zhang, HF Wu, ZD Zhang, ZJ Wang, LX Hua, NH Feng, XR Wang
Molecular Biology Reports 2010
Interleukin-6 promoter polymorphism −174 G/C is associated with nephritis in Portuguese Caucasian systemic lupus erythematosus patients
MJ Santos, D Fernandes, S Capela, JC Silva, JE Fonseca
Clinical Rheumatology 2010
The polymorphisms G(−174)C in IL6 gene and G(−1082)A in IL10 gene are associated with poor outcomes in patients with acute coronary syndrome
KA Blagodatskikh, MA Evdokimova, YV Agapkina, AG Nikitin, AN Brovkin, AA Pushkov, EG Blagodatskikh, OY Kudryashova, VS Osmolovskaya, LO Minushkina, MS Kochkina, ND Selezneva, EN Dankovtseva, OS Chumakova, TN Baklanova, PA Talyzin, NE Reznichenko, OP Donetskaya, SN Tereshchenko, ES Krasil’nikova, NA Dzhaiani, EV Akatova, MG Glezer, AS Galyavich, VB Zakirova, NA Koziolova, IV Timofeeva, AV Yagoda, OI Boeva, LI Katel’nitskaya, EV Khorolets, SV Shlyk, EG Volkova, MP Margaryan, IO Guz’, VO Konstantinov, NV Timofeeva, BA Sidorenko, DA Zateishchikov, VV Nosikov
Molecular Biology 2010
Interleukin 6 promoter polymorphisms influence the outcome of chronic hepatitis C
A Cussigh, E Falleti, C Fabris, D Bitetto, S Cmet, E Fontanini, S Bignulin, E Fornasiere, E Fumolo, R Minisini, M Pirisi, P Toniutto
Immunogenetics 2010
HLA-DRB1*1501 intensifies the impact of IL-6 promoter polymorphism on the susceptibility to multiple sclerosis in an Iranian population
M Shahbazi, H Ebadi, D Fathi, D Roshandel, M Mohamadhosseni, A Tahmasebi, S Shahbazi, M Zamani, A Rashidbaghan
Multiple sclerosis (Houndmills, Basingstoke, England) 2010
Gene Polymorphisms in Chronic Periodontitis
ML Laine, BG Loos, W Crielaard
International journal of dentistry 2010
Association of Interleukin-6 Haplotypes, Obesity, and Metabolic Abnormalities in a Population of Central Mexico
I Zamora-Ginez, MC Sánchez-Guillén, R Pérez-Fuentes, BG Baez-Duarte, E Brambila, A García-Zapién, F Mendoza-Carrera
Laboratory Medicine 2010
The Role of Genetic Variation in Muscle Strength
M Kostek, MJ Hubal, LS Pescatello
American journal of lifestyle medicine 2010
Are elite endurance athletes genetically predisposed to lower disease risk?
F Gómez-Gallego, JR Ruiz, A Buxens, S Altmäe, M Artieda, C Santiago, M González-Freire, Z Verde, D Arteta, A Martínez, D Tejedor, JI Lao, J Arenas, A Lucia
Physiological genomics 2010
Interleukin 6 Gene Polymorphisms Are Associated with Systemic Lupus Erythematosus in Koreans
JY Jeon, HA Kim, SH Kim, HS Park, CH Suh
The Journal of rheumatology 2010
Polymorphism in interleukin-6 gene is associated with bone mineral density in patients with adolescent idiopathic scoliosis
JS Lee, KT Suh, IS Eun
The Journal of Bone & Joint Surgery 2010
Molecular Basis for Therapy of AIDS-Defining Cancers
DP Dittmer, SE Krown
2010
Intelligent Information and Database Systems
NT Nguyen, MT Le, J Świątek
2010
Chemo Fog
RB Raffa, RJ Tallarida
2010
Interleukin-1 beta and interleukin-6 gene polymorphism associations with angiographically assessed coronary artery disease in Brazilians
DL Rios, CC Cerqueira, R Bonfim-Silva, LJ Araújo, JF Pereira, SR Gadelha, AA Barbosa
Cytokine 2010
Biological pathways and genetic variables involved in pain.
Shi Q, Cleeland CS, Klepstad P, Miaskowski C, Pedersen NL
Quality of Life Research 2010
Polymorphisms of IL-6 174 G/C, IL-10 -592 C/A and risk of HIV/AIDS among North Indian population.
Sobti RC, Berhane N, Mahedi SA, Kler R, Hosseini SA, Kuttiat V, Wanchu A
Molecular and Cellular Biochemistry 2010
The IL-6 -174G/C polymorphism and renal scarring in children with first acute pyelonephritis.
Spasojević-Dimitrijeva B, Zivković M, Stanković A, Stojković L, Kostić M
Pediatric nephrology (Berlin, Germany) 2010
Graves' disease and gene polymorphism of TNF-α, IL-2, IL-6, IL-12, and IFN-γ.
Anvari M, Khalilzadeh O, Esteghamati A, Momen-Heravi F, Mahmoudi M, Esfahani SA, Rashidi A, Amirzargar A
Endocrine 2010
Interleukin 6 promoter polymorphisms influence the outcome of chronic hepatitis C.
Cussigh A, Falleti E, Fabris C, Bitetto D, Cmet S, Fontanini E, Bignulin S, Fornasiere E, Fumolo E, Minisini R, Pirisi M, Toniutto P
Immunogenetics 2010
IL-6 -174G>C polymorphism and cancer risk: a meta-analysis involving 29,377 cases and 37,739 controls.
Xu B, Niu XB, Wang ZD, Cheng W, Tong N, Mi YY, Min ZC, Tao J, Li PC, Zhang W, Wu HF, Zhang ZD, Wang ZJ, Hua LX, Feng NH, Wang XR
Molecular Biology Reports 2010
A variant near the interleukin-6 gene is associated with fat mass in Caucasian men.
Andersson N, Strandberg L, Nilsson S, Adamovic S, Karlsson MK, Ljunggren O, Mellström D, Lane NE, Zmuda JM, Nielsen C, Orwoll E, Lorentzon M, Ohlsson C, Jansson JO
International Journal of Obesity 2010
Interleukin-6 promoter polymorphism -174 G/C is associated with nephritis in Portuguese Caucasian systemic lupus erythematosus patients.
Santos MJ, Fernandes D, Capela S, da Silva JC, Fonseca JE
Clinical Rheumatology 2010
Influence of IL1B polymorphism on CpG island hypermethylation in Helicobacter pylori-infected gastric cancer.
Yoo EJ, Park SY, Cho NY, Kim N, Lee HS, Kim D, Kang GH
Virchows Archiv : an international journal of pathology 2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)
SL Masters, A Simon, I Aksentijevich, DL Kastner
Annual Review of Immunology 2009
Role for Interleukin-6 in COPD-Related Pulmonary Hypertension
A Chaouat, L Savale, C Chouaid, L Tu, B Sztrymf, M Canuet, B Maitre, B Housset, C Brandt, PL Corvoisier, E Weitzenblum, S Eddahibi, S Adnot
Chest 2009
Serum interleukin-6 levels in colorectal cancer patients—a summary of published results
H Knüpfer, R Preiss
International Journal of Colorectal Disease 2009
Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer
KK Tsilidis, KJ Helzlsouer, MW Smith, V Grinberg, J Hoffman-Bolton, SL Clipp, K Visvanathan, EA Platz
Cancer Causes & Control 2009
Genetic ancestry modifies pharmacogenetic gene–gene interaction for asthma
Corvol H, De Giacomo A, Eng C, Seibold M, Ziv E, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Thyne S, Watson HG, Meade K, LeNoir M, Avila PC, Choudhry S, Burchard EG
Pharmacogenetics and Genomics 2009
Frontiers in Neuroscience
K Panickar, S Bhathena
Fat Detection 2009
Interleukin-6 promoter polymorphism and cardiovascular risk factors: The Health 2000 Survey
A Riikola, K Sipilä, M Kähönen, A Jula, MS Nieminen, L Moilanen, YA Kesäniemi, T Lehtimäki, J Hulkkonen
Atherosclerosis 2009
Phospholipase A2 and cyclooxygenase 2 genes influence the risk of interferon-alpha-induced depression by regulating polyunsaturated fatty acids levels
KP Su, SY Huang, CY Peng, HC Lai, CL Huang, YC Chen, KJ Aitchison, CM Pariante
Biological Psychiatry 2009
Optimized PCR with sequence specific primers (PCR-SSP) for fast and efficient determination of Interleukin-6 Promoter -597/-572/-174Haplotypes
M Müller-Steinhardt, F Schulte, H Klüter, P Bugert
BMC Research Notes 2009
PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3)
L Dossus, R Kaaks, F Canzian, D Albanes, SI Berndt, H Boeing, J Buring, SJ Chanock, F Clavel-Chapelon, HS Feigelson, JM Gaziano, E Giovannucci, C Gonzalez, CA Haiman, G Hallmans, SE Hankinson, RB Hayes, BE Henderson, RN Hoover, DJ Hunter, KT Khaw, LN Kolonel, P Kraft, J Ma, LL Marchand, E Lund, PH Peeters, M Stampfer, DO Stram, G Thomas, MJ Thun, A Tjonneland, D Trichopoulos, R Tumino, E Riboli, J Virtamo, SJ Weinstein, M Yeager, RG Ziegler, DG Cox
Carcinogenesis 2009
Interleukin-6 polymorphisms modify the risk of periodontitis: a systematic review and meta-analysis
M Shao, P Huang, R Cheng, T Hu
Journal of Zhejiang University. Science. B 2009
Variation in cytokine genes can contribute to severity of acetabular osteolysis and risk for revision in patients with ABG 1 total hip arthroplasty: a genetic association study
J Gallo, F Mrazek, M Petrek
BMC Medical Genetics 2009
Systemic JIA: new developments in the understanding of the pathophysiology and therapy
SJ Vastert, W Kuis, AA Grom
Best practice & research. Clinical rheumatology 2009
A polymorphism in NFKB1 is associated with improved effect of interferon-{alpha} maintenance treatment of patients with multiple myeloma after high-dose treatment with stem cell support
AJ Vangsted, TW Klausen, P Gimsing, NF Andersen, N Abildgaard, H Gregersen, U Vogel
Haematologica 2009
Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease
O Combarros, CM van Duijn, N Hammond, O Belbin, A Arias-Vásquez, M Cortina-Borja, MG Lehmann, YS Aulchenko, M Schuur, H Kölsch, R Heun, GK Wilcock, K Brown, PG Kehoe, R Harrison, E Coto, V Alvarez, P Deloukas, I Mateo, R Gwilliam, K Morgan, DR Warden, AD Smith, DJ Lehmann
Journal of Neuroinflammation 2009
What epidemiology has told us about risk factors and aetiopathogenesis in rheumatic diseases
JE Oliver, AJ Silman
Arthritis Research & Therapy 2009
Bench-to-bedside review: Association of genetic variation with sepsis
AM Sutherland, KR Walley
Critical Care 2009
Interleukin-6 plasma level increases with age in an Italian elderly population ("The Treviso Longeva"-Trelong-study) with a sex-specific contribution of rs1800795 polymorphism
D Albani, S Batelli, L Polito, F Prato, M Pesaresi, GB Gajo, SD Angeli, A Zanardo, D Galimberti, E Scarpini, M Gallucci, G Forloni
Age (Dordrecht, Netherlands) 2009
Associations of IL6 polymorphisms with lung function decline and COPD
JQ He, MG Foreman, K Shumansky, X Zhang, L Akhabir, DD Sin, SF Man, DL DeMeo, AA Litonjua, EK Silverman, JE Connett, NR Anthonisen, RA Wise, PD Paré, AJ Sandford
Thorax 2009
C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older
BL Pierce, ML Biggs, M DeCambre, AP Reiner, C Li, A Fitzpatrick, CS Carlson, JL Stanford, MA Austin
Cancer causes & control : CCC 2009
Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion
I Steinbrugger, A Haas, R Maier, W Renner, M Mayer, C Werner, A Wedrich, Y El-Shabrawi, O Schmut, M Weger
Molecular vision 2009
The −174 G/C Polymorphism in Interleukin-6 (IL-6) Promoter Region is Associated with Serum IL-6 and Carcinoembryonic Antigen Levels in Patients with Colorectal Cancers in Taiwan
KY Yeh, YY Li, LL Hsieh, JR Chen, RP Tang
Journal of Clinical Immunology 2009
The −174GG Interleukin-6 Genotype Is Protective From Retinopathy and Nephropathy in Juvenile Onset Type 1 Diabetes Mellitus
J Myśliwska, K Zorena, M Myśliwiec, E Malinowska, K Raczyńska, A Balcerska
Pediatric Research 2009
DNA variants, plasma levels and variability of Interleukin-6 in myocardial infarction survivors: Results from the AIRGENE study
P Ljungman, T Bellander, F Nyberg, E Lampa, B Jacquemin, M Kolz, T Lanki, J Mitropoulos, M Müller, S Picciotto, R Pistelli, R Rückerl, W Koenig, A Peters
Thrombosis Research 2009
Association between genetic polymorphisms in cytokine genes and recurrent miscarriage – a meta-analysis
I Medica, S Ostojic, N Pereza, A Kastrin, B Peterlin
Reproductive BioMedicine Online 2009
Polymorphism in the IL6 promoter region is associated with the risk factors and markers of subclinical atherosclerosis in men: The Cardiovascular Risk in Young Finns Study
J Hulkkonen, T Lehtimäki, N Mononen, M Juonala, N Hutri-Kähönen, L Taittonen, J Marniemi, T Nieminen, J Viikari, O Raitakari, M Kähönen
Atherosclerosis 2009
Gene polymorphism at the interleukin 6 -174 G&gt;C locus affects the outcome of chronic hepatitis B
C Fabris, P Toniutto, D Bitetto, G Fattovich, E Falleti, E Fontanini, A Cussigh, R Minisini, G Occhino, M Pirisi
Journal of Infection 2009
Comparative analysis of IL6 promoter and receptor polymorphisms in myelodysplasia and multiple myeloma
I Aladzsity, M Kovács, Á Semsei, A Falus, Á Szilágyi, I Karádi, G Varga, G Füst, J Várkonyi
Leukemia Research 2009
Is Still's disease an autoinflammatory syndrome?
F Hayem
Joint Bone Spine 2009
Gene polymorphisms and pharmacogenetics in rheumatoid arthritis
I Rego-Pérez, M Fernández-Moreno, V Carreira-García, FJ Blanco
Reumatolog ía Cl ínica (English Edition) 2009
Interleukin-6 -174 and -572 Genotypes and the Volume of Deep Gray Matter in Preterm Infants
M Reiman, R Parkkola, H Lapinleimu, L Lehtonen, L Haataja
Pediatric Research 2009
Kelley's Textbook of Rheumatology
J Degroot, AM Zuurmond, PP Tak
Kelley's Textbook of Rheumatology 2009
Translational strategies to implement personalized medicine: rheumatoid arthritis examples
BH Littman
Personalized Medicine 2009
The impact of "high-producer" interleukin-6 haplotypes on cardiovascular morbidity and mortality in a kidney transplant population
B Krüger, A Walberer, S Farkas, F Tokmak, A Obed, P Schenker, B Henning, HJ Schlitt, BK Krämer, B Banas
Transplantation Proceedings 2009
Lack of an association between a functional polymorphism in the interleukin-6 gene promoter and breast cancer risk: a meta-analysis involving 25,703 subjects
KD Yu, GH Di, L Fan, AX Chen, C Yang, ZM Shao
Breast Cancer Research and Treatment 2009
Oligoarticular and polyarticular JIA: epidemiology and pathogenesis
C Macaubas, K Nguyen, D Milojevic, JL Park, ED Mellins
Nature Reviews Rheumatology 2009
Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index
C Huth, T Illig, C Herder, C Gieger, H Grallert, C Vollmert, W Rathmann, YH Hamid, O Pedersen, T Hansen, B Thorand, C Meisinger, A Doring, N Klopp, H Gohlke, W Lieb, C Hengstenberg, V Lyssenko, L Groop, H Ireland, JW Stephens, IW Asterholm, JO Jansson, H Boeing, M Mohlig, HM Stringham, M Boehnke, J Tuomilehto, JM Fernandez-Real, A Lopez-Bermejo, L Gallart, J Vendrell, SE Humphries, F Kronenberg, HE Wichmann, IM Heid
Annals of Medicine 2009
Polimorfismos genéticos y farmacogenética en la artritis reumatoide
I Rego-Pérez, M Fernández-Moreno, V Carreira-García, FJ Blanco
Reumatología Clínica 2009
Host Genetic Variants in the Interleukin-6 Promoter Predict Poor Outcome in Patients with Estrogen Receptor-Positive, Node-Positive Breast Cancer
A DeMichele, R Gray, M Horn, J Chen, R Aplenc, WP Vaughan, MS Tallman
Cancer research 2009
The interleukin-6, serotonin transporter, and monoamine oxidase A genes and endurance performance during the South African Ironman Triathlon
L Milander, DJ Stein, M Collins
Applied Physiology, Nutrition, and Metabolism 2009
Interleukin-6 genotype and risk for cerebral palsy in term and near-term infants
YW Wu, LA Croen, AR Torres, JV de Water, JK Grether, NN Hsu
Annals of Neurology 2009
The Additive Contribution from Inflammatory Genetic Markers on the Severity of Cardiovascular Disease
KK Berg, HO Madsen, P Garred, R Wiseth, S Gunnes, V Videm
Scandinavian Journal of Immunology 2009
Implications of cytokine gene polymorphisms on the orchestration of the immune response: Lessons learned from oral diseases
WO Dutra, PR Moreira, PE Souza, KJ Gollob, RS Gomez
Cytokine & Growth Factor Reviews 2009
Higher IL-6 levels but not IL6 −174G>C or −572G>C genotype are associated with post-operative complication following coronary artery bypass graft (CABG) surgery
J Sanders, E Hawe, DJ Brull, C Hubbart, GD Lowe, A Rumley, SE Humphries, HE Montgomery
Atherosclerosis 2009
The influence of class II transactivator and interleukin-6 polymorphisms on the production of antibodies to donor human leucocyte antigen mismatches in renal allograft recipients
J Martin, J Worthington, S Harris, S Martin
International Journal of Immunogenetics 2009
IL6 genotype and creatine kinase response to exercise
J Lappalainen
European Journal of Applied Physiology 2009
IL-6 −174 genotype associated with the extent of periodontal disease in type 1 diabetic subjects
T Raunio, M Knuuttila, L Hiltunen, R Karttunen, O Vainio, T Tervonen
Journal of Clinical Periodontology 2009
Genetic polymorphisms in non-alcoholic fatty liver disease: Interleukin-6−174G/C polymorphism is associated with non-alcoholic steatohepatitis
L Carulli, I Canedi, S Rondinella, S Lombardini, D Ganazzi, S Fargion, MD Palma, A Lonardo, M Ricchi, M Bertolotti, N Carulli, P Loria
Digestive and Liver Disease 2009
Influence of interleukin-6 G-174C gene polymorphism on coronary artery disease, cardiovascular complications and mortality in dialysis patients
S Aker, C Bantis, P Reis, N Kuhr, C Schwandt, B Grabensee, P Heering, K Ivens
Nephrology Dialysis Transplantation 2009
The Effects of Genetic Polymorphisms of IL-6, IL-8, and IL-10 on Helicobacter pylori-induced Gastroduodenal Diseases in Korea:
JM Kang, N Kim, DH Lee, JH Park, MK Lee, JS Kim, HC Jung, IS Song
Journal of Clinical Gastroenterology 2009
Differential cytokine profiles in juvenile idiopathic arthritis subtypes revealed by cluster analysis
HJ Ham, W Jager, JW Bijlsma, BJ Prakken, RJ de Boer
Rheumatology 2009
Cytokine and cytokine receptor gene polymorphisms and their functionality
AJ Smith, SE Humphries
Cytokine & Growth Factor Reviews 2009
Periodontal infectogenomics
L Nibali, N Donos, B Henderson
Journal of Medical Microbiology 2009
Gene–gene interaction between CARD8 and interleukin-6 reduces Alzheimer’s disease risk
A Fontalba, O Gutiérrez, J Llorca, I Mateo, JL Vázquez-Higuera, J Berciano, JL Fernández-Luna, O Combarros
Journal of Neurology 2009
Fatty Acids, IL6, and TNFα Polymorphisms: An Example of Nutrigenetics in Crohn's Disease
CS Guerreiro, P Ferreira, L Tavares, PM Santos, M Neves, M Brito, M Cravo
The American Journal of Gastroenterology 2009
The IL6 -174G/C polymorphism is associated with celiac disease susceptibility in girls
B Dema, A Martínez, M Fernández-Arquero, C Maluenda, I Polanco, MÁ Figueredo, EG de la Concha, E Urcelay, C Núñez
Human Immunology 2009
Effect of interleukin-6 polymorphisms on human longevity: A systematic review and meta-analysis
DD Bona, S Vasto, C Capurso, L Christiansen, L Deiana, C Franceschi, M Hurme, E Mocchegiani, M Rea, D Lio, G Candore, C Caruso
Ageing Research Reviews 2009
Genetic susceptibility to viral exposure may increase the risk of cerebral palsy
M DJUKIC, CS GIBSON, AH MacLENNAN, PN GOLDWATER, EA HAAN, G McMICHAEL, K PRIEST, GA DEKKER, WM HAGUE, A CHAN, Z RUDZKI, PV ESSEN, TY KHONG, MR MORTON, E RANIERI, H SCOTT, H TAPP, G CASEY
Australian and New Zealand Journal of Obstetrics and Gynaecology 2009
Association of interleukin-6 (IL-6)-174G/C gene polymorphism with cardiovascular disease in patients with rheumatoid arthritis: The role of obesity and smoking
VF Panoulas, A Stavropoulos-Kalinoglou, GS Metsios, JP Smith, HJ Milionis, KM Douglas, P Nightingale, GD Kitas
Atherosclerosis 2009
Effects of CD14, TLR2, TLR4, LPB, and IL-6 Gene Polymorphisms on Chlamydia pneumoniae Growth in Human Macrophages In Vitro
K Poikonen, T Lajunen, S Silvennoinen-Kassinen, M Leinonen, P Saikku
Scandinavian Journal of Immunology 2009
Polymorphisms of IL-6 174 G/C, IL-10 -592 C/A and risk of HIV/AIDS among North Indian population
RC Sobti, N Berhane, SA Mahedi, R Kler, SA Hosseini, V Kuttiat, A Wanchu
Molecular and Cellular Biochemistry 2009
The (-174) G/C polymorphism in the interleukin-6 gene is associated with risk of papillary thyroid carcinoma in Turkish patients
AG Özgen, M Karadeniz, M Erdogan, A Berdeli, F Saygili, C Yilmaz
Journal of Endocrinological Investigation 2009
Association between IL6 gene variants −174G>C and −572G>C and serum IL-6 levels: Interactions with social position in the Whitehall II cohort
SC Sanderson, M Kumari, EJ Brunner, MA Miller, A Rumley, GD Lowe, MG Marmot, SE Humphries
Atherosclerosis 2009
Interaction between smoking and the interleukin-6 gene affects systemic levels of inflammatory biomarkers
J Sunyer, F Forastiere, J Pekkanen, E Plana, M Kolz, R Pistelli, B Jacquemin, I Bruske-Hohlfeld, C Pitsavos, T Bellander, W Koenig, A Peters
Nicotine & Tobacco Research 2009
Tocilizumab and missed personalized medicine opportunities for patients with rheumatoid arthritis?
BH Littman
Arthritis & Rheumatism 2009
Association of HLA-DRB1, interleukin-6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population-A candidate gene approach
FA Castro, K Haimila, I Sareneva, M Schmitt, J Lorenzo, N Kunkel, R Kumar, A Försti, L Kjellberg, G Hallmans, M Lehtinen, K Hemminki, M Pawlita
International Journal of Cancer 2009
Polymorphisms at GLUT1 gene are not associated with the development of TSP/HAM in Brazilian HTLV-1 infected individuals and the discovery of a new polymorphism at GLUT1 gene
GC Costa, R Azevedo, SR Gadelha, SH Kashima, G Muricy, VN Olavarria, DT Covas, OM Takayanagui, B Galvão-Castro, LC Alcantara
Journal of Medical Virology 2009
Day-to-day variation in plasma interleukin-6 concentrations in older adults
M Picotte, CG Campbell, WG Thorland
Cytokine 2009
Association of IL6 and CCL2 gene polymorphisms with the outcome of allogeneic haematopoietic stem cell transplantation
Z Ambruzova, F Mrazek, L Raida, P Jindra, B Vidan-Jeras, E Faber, J Pretnar, K Indrak, M Petrek
Bone Marrow Transplantation 2009
La maladie de Still : une maladie auto-inflammatoire ?
F Hayem
Revue du Rhumatisme 2009
Molecular screening of interleukin-6 gene promoter and influence of −174G/C polymorphism on breast cancer
M Chérel, L Campion, S Bézieau, M Campone, J Charrier, J Gaschet, G Ricolleau, W Gouraud, C Charbonnel, P Jézéquel
Cytokine 2009
Proinflammatory Cytokine Gene Polymorphisms in Irritable Bowel Syndrome
E Barkhordari, N Rezaei, B Ansaripour, P Larki, M Alighardashi, HR Ahmadi-Ashtiani, M Mahmoudi, MR Keramati, P Habibollahi, M Bashashati, N Ebrahimi-Daryani, AA Amirzargar
Journal of Clinical Immunology 2009
A common variation in the promoter region of interleukin-6 gene shows association with exercise performance
A Huuskonen, M Tanskanen, J Lappalainen, N Oksala, H Kyröläinen, M Atalay
Journal of sports science & medicine 2009
Association between metabolic disturbances and G-174C polymorphism of interleukin-6 gene in obese children
B Pyrzak, A Wisniewska, A Majcher, K Popko, M Wasik, U Demkow
European Journal of Medical Research 2009
Pathogenic mechanisms of postinfectious functional gastrointestinal disorders: Results 3 years after gastroenteritis
F Mearin, A Perelló, A Balboa, M Perona, M Sans, A Salas, S Angulo, J Lloreta, R Benasayag, MA García-Gonzalez, M Pérez-Oliveras, J Coderch
Scandinavian Journal of Gastroenterology 2009
Joint analysis of individual participants’ data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index
C Huth, T Illig, C Herder, C Gieger, H Grallert, C Vollmert, W Rathmann, YH Hamid, O Pedersen, T Hansen, B Thorand, C Meisinger, A Döring, N Klopp, H Gohlke, W Lieb, C Hengstenberg, V Lyssenko, L Groop, H Ireland, JW Stephens, IW Asterholm, JO Jansson, H Boeing, M Möhlig, HM Stringham, M Boehnke, J Tuomilehto, JM Fernandez-Real, A Lopez-Bermejo, L Gallart, J Vendrell, SE Humphries, F Kronenberg, HE Wichmann, IM Heid
Annals of Medicine 2009
Immuno-Modulatory Gene Polymorphisms and Outcome in Breast and Ovarian Cancer
S Kim, A Hagemann, A DeMichele
Immunological Investigations 2009
Gene polymorphisms of TNF-α −308 (G/A), IL-10 −1082 (G/A), IL-6 −174 (G/C) and IL-1Ra (VNTR) in Egyptian cases with type 1 diabetes mellitus
A Settin, A Ismail, MA El-Magd, R El-Baz, A Kazamel
Autoimmunity 2009
Interleukin-6 promoter polymorphisms (-174 G/C) in Malaysian patients with systemic lupus erythematosus
KH Chua, BP Kee, SY Tan, LH Lian
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] 2009
Association of interleukin-18 promoter polymorphisms with WHO pathological classes and serum IL-18 levels in Chinese patients with lupus nephritis
DY Chen, CW Hsieh, KS Chen, YM Chen, FJ Lin, JL Lan
Lupus 2009
Tumor Necrosis Factor-α −308 Genotypes Influence Inflammatory Activity and TNF-α Serum Concentrations in Children with Juvenile Idiopathic Arthritis
AF Mourão, J Caetano-Lopes, P Costa, H Canhão, MJ Santos, P Pinto, IV Brito, P Nicola, J Cavaleiro, J Teles, A Sousa, JM Gomes, J Branco, JO da COSTA, JG Pedro, MÁ de QUEIROZ, JE Fonseca
The Journal of rheumatology 2009
Functional Association of Interleukin 18 Gene −607 (C/A) Promoter Polymorphisms with Disease Course in Chinese Patients with Adult-onset Still’s Disease
DY Chen, YM Chen, HH Chen, CW Hsieh, CC Lin, JL Lan
The Journal of rheumatology 2009
Association of Interleukin-6 –174G>C Promoter Polymorphism with Risk of Cervical Cancer
R Gangwar, B Mittal, RD Mittal
The International Journal of Biological Markers 2009
Handbook on Immunosenescence
T Fulop, C Franceschi, K Hirokawa, G Pawelec
2009
Cytokine Polymorphisms in the Pathophysiology of Mood Disorders
M Clerici, B Arosio, E Mundo, E Cattaneo, S Pozzoli, B Dell'Osso, C Vergani, D Trabattoni, AC Altamura
CNS Spectrums 2009
Influence of proinflammatory cytokine gene polymorphism on childhood obesity
K Popko, E Górska, B Pyrzak, A Telmaszczyk-Emmel, A Wisniewska, A Majcher, M Wasik, U Demkow
European Journal of Medical Research 2009
Prognostic Significance of Interleukin-6 Single Nucleotide Polymorphism Genotypes in Neuroblastoma: rs1800795 (Promoter) and rs8192284 (Receptor)
JP Lagmay, WB London, TG Gross, A Termuhlen, N Sullivan, A Axel, B Mundy, M Ranalli, J Canner, P McGrady, B Hall
Clinical cancer research 2009
Insulin-like Growth Factor-1- and Interleukin-6-related Gene Variation and Risk of Multiple Myeloma: Table 1
BM Birmann, RM Tamimi, E Giovannucci, B Rosner, DJ Hunter, P Kraft, C Mitsiades, KC Anderson, GA Colditz
Cancer epidemiology, biomarkers & prevention 2009
Gene-gene interaction between CARD8 and interleukin-6 reduces Alzheimer's disease risk.
Fontalba A, Gutiérrez O, Llorca J, Mateo I, Vázquez-Higuera JL, Berciano J, Fernández-Luna JL, Combarros O
Journal of Neurology 2009
IL6 genotype and creatine kinase response to exercise.
Lappalainen J
European Journal of Applied Physiology 2009
Interleukin-6 haplotypes and the response to therapy of chronic hepatitis C virus infection.
Yee LJ, Im K, Borg B, Yang H, Liang TJ
Genes and Immunity 2009
The (-174) G/C polymorphism in the interleukin-6 gene is associated with risk of papillary thyroid carcinoma in Turkish patients.
Ozgen AG, Karadeniz M, Erdogan M, Berdeli A, Saygili F, Yilmaz C
Journal of Endocrinological Investigation 2009
Proinflammatory cytokine gene polymorphisms in irritable bowel syndrome.
Barkhordari E, Rezaei N, Ansaripour B, Larki P, Alighardashi M, Ahmadi-Ashtiani HR, Mahmoudi M, Keramati MR, Habibollahi P, Bashashati M, Ebrahimi-Daryani N, Amirzargar AA
Journal of Clinical Immunology 2009
Hematopoietic Stem Cell Transplantation
MR Bishop
2008
Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways
ML Slattery, RK Wolff, K Curtin, F Fitzpatrick, J Herrick, JD Potter, BJ Caan, WS Samowitz
Mutation research 2008
Making genomics functional: deciphering the genetics of acute lung injury
R Kamp, X Sun, JG Garcia
Proceedings of the American Thoracic Society 2008
Gene expression polymorphisms of interleukins-1 beta, -4, -6, -8, -10, and tumor necrosis factors-alpha, -beta: regression analysis of their effect upon oral squamous cell carcinoma.
Vairaktaris E, Yapijakis C, Serefoglou Z, Avgoustidis D, Critselis E, Spyridonidou S, Vylliotis A, Derka S, Vassiliou S, Nkenke E, Patsouris E
Journal of Cancer Research and Clinical Oncology 2008
Ambivalent aspects of interleukin-6 in cerebral ischemia: inflammatory versus neurotrophic aspects
S Suzuki, K Tanaka, N Suzuki
Journal of Cerebral Blood Flow & Metabolism 2008
Clinical Immunology
DB Kuhns
Clinical Immunology 2008
Type 1 diabetes: can exercise impair the autoimmune event? TheL-arginine/glutamine coupling hypothesis
MS Krause, PI de Bittencourt
Cell Biochemistry and Function 2008
Clinical Significance of Interleukin-6 (Il-6) Gene Polymorphism and Il-6 Serum Level in Pancreatic Adenocarcinoma and Chronic Pancreatitis
R Talar-Wojnarowska, A Gasiorowska, B Smolarz, H Romanowicz-Makowska, A Kulig, E Malecka-Panas
Digestive Diseases and Sciences 2008
Impact of cytokine gene polymorphisms on graft-vs-host disease
KA Markey, KP MacDonald, GR Hill
Tissue Antigens 2008
REVIEW ARTICLE: Cytokine Gene Polymorphisms in Recurrent Spontaneous Abortions: A Comprehensive Review
YK Choi, J Kwak-Kim
American Journal of Reproductive Immunology 2008
Association of interleukin-6 (−174G>C) promoter polymorphism with risk of squamous cell esophageal cancer and tumor location: An exploratory study
R Upadhyay, M Jain, S Kumar, UC Ghoshal, B Mittal
Clinical Immunology 2008
Inflammatory cytokine gene variants in coronary artery disease patients in Greece
A Manginas, A Tsiavou, A Chaidaroglou, G Giamouzis, D Degiannis, D Panagiotakos, DV Cokkinos
Coronary Artery Disease 2008
Giant cell arteritis and polymyalgia rheumatica: Role of cytokines in the pathogenesis and implications for treatment
VM Martinez-Taboada, L Alvarez, M RuizSoto, MJ Marin-Vidalled, M Lopez-Hoyos
Cytokine 2008
Influence of Cytokine Gene Polymorphisms on IgA Nephropathy
C Bantis, P Heering, S Aker, N Kuhr, B Grabensee, K Ivens
Renal Failure 2008
The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN studyboxs
J Shen, DK Arnett, P Pérez-Martínez, LD Parnell, CQ Lai, JM Peacock, JE Hixson, MY Tsai, RJ Straka, PN Hopkins, JM Ordovás
Journal of lipid research 2008
IL6 and IL1B Polymorphisms are Associated With Fat Mass in Older Men: The MrOS Study Sweden
L Strandberg, D Mellström, Ö Ljunggren, E Grundberg, MK Karlsson, AH Holmberg, ES Orwoll, AL Eriksson, J Svedberg, M Bengtsson, C Ohlsson, JO Jansson
Obesity 2008
Gene polymorphisms and pharmacogenetics in rheumatoid arthritis
I Rego-Pérez, M Fernández-Moreno, FJ Blanco
Current genomics 2008
Circulating prediagnostic interleukin-6 and C-reactive protein and prostate cancer incidence and mortality
JR Stark, H Li, P Kraft, T Kurth, EL Giovannucci, MJ Stampfer, J Ma, LA Mucci
International Journal of Cancer 2008
Zinc-gene interaction related to inflammatory/immune response in ageing
E Mocchegiani, M Malavolta
Genes & Nutrition 2008
Interleukin and interleukin receptor gene polymorphisms and susceptibility to melanoma
F Gu, AA Qureshi, T Niu, P Kraft, Q Guo, DJ Hunter, J Han
Melanoma Research 2008
Effect of cytokine and pharmacogenomic genetic polymorphisms in transplantation
DM Girnita, G Burckart, A Zeevi
Current Opinion in Immunology 2008
Cytokine gene polymorphisms and fatigue in breast cancer survivors: early findings
A Collado-Hidalgo, JE Bower, PA Ganz, MR Irwin, SW Cole
Brain, Behavior, and Immunity 2008
An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients
DP Ng, S Nurbaya, SH Ye, AS Krolewski
Kidney International 2008
Common studied polymorphisms do not affect plasma cytokine levels upon endotoxin exposure in humans
S Taudorf, KS Krabbe, RM Berg, K Møller, BK Pedersen, H Bruunsgaard
Clinical & Experimental Immunology 2008
Neuroendocrine-immune mechanisms of behavioral comorbidities in patients with cancer
AH Miller, S Ancoli-Israel, JE Bower, L Capuron, MR Irwin
Journal of Clinical Oncology 2008
Common interleukin-6 promoter variants associate with the more severe forms of distal interphalangeal osteoarthritis
OP Kämäräinen, S Solovieva, T Vehmas, K Luoma, H Riihimäki, L Ala-Kokko, M Männikkö, P Leino-Arjas
Arthritis Research & Therapy 2008
Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk
ML Slattery, K Curtin, C Sweeney, RK Wolff, RN Baumgartner, KB Baumgartner, AR Giuliano, T Byers
Obesity (Silver Spring, Md.) 2008
Clone-specific expression, transcriptional regulation, and action of interleukin-6 in human colon carcinoma cells
W Brozek, G Bises, G Fabjani, HS Cross, M Peterlik
BMC Cancer 2008
Abatacept in difficult-to-treat juvenile idiopathic arthritis
JB Kuemmerle-Deschner, S Benseler
Biologics : targets & therapy 2008
Biological therapies for the treatment of juvenile idiopathic arthritis: Lessons from the adult and pediatric experiences
ML Stoll, AC Gotte
Biologics : targets & therapy 2008
The interleukin-6-174 G/C promoter polymorphism and arterial stiffness; the Rotterdam Study
MP Sie, FU Mattace-Raso, AG Uitterlinden, PP Arp, A Hofman, HA Pols, AP Hoeks, RS Reneman, R Asmar, CM van Duijn, JC Witteman
Vascular Health and Risk Management 2008
Psychoneuroimmunology
F Tausk, I Elenkov, J Moynihan
Dermatologic Therapy 2008
Association of cytokine gene polymorphisms in CWP and its severity in Turkish coal workers
I Ates, HS Suzen, B Yucesoy, IO Tekin, A Karakaya
American Journal of Industrial Medicine 2008
Interleukin-6 (IL-6), Tumor Necrosis Factor-α (TNF-α) Levels and IL-6, TNF-Polymorphisms in Children With Thrombosis
S Unal, F Gumruk, S Aytac, D Yalnzoglu, A Gurgey
Journal of Pediatric Hematology/Oncology 2008
Ability of epistatic interactions of cytokine single‐nucleotide polymorphisms to predict susceptibility to disease subsets in systemic sclerosis patients
L Beretta, F Cappiello, JH Moore, M Barili, CS Greene, R Scorza
Arthritis & Rheumatism 2008
Contribution of Gender-Specific Genetic Factors to Osteoporosis Risk
D Karasik, SL Ferrari
Annals of Human Genetics 2008
Cytokine gene polymorphism in kidney transplantation — Impact of TGF-β1, TNF-α and IL-6 on graft outcome
PN Nikolova, MI Ivanova, SM Mihailova, AP Myhailova, DN Baltadjieva, PL Simeonov, EK Paskalev, EJ Naumova
Transplant Immunology 2008
Cancer Immunology
OJ Finn
New England Journal of Medicine 2008
Inflammatory cytokines in juvenile idiopathic arthritis: Effects on physical growth and the insulin-like-growth factor axis
SC Wong, VE MacRae, JA Gracie, IB McInnes, P Galea, J Gardner-Medwin, SF Ahmed
Growth Hormone & IGF Research 2008
Association of IL-6 gene polymorphisms and COPD in a Spanish Population
E Córdoba-Lanús, JP de-Torres, C López-Aguilar, MC Rodríguez-Pérez, N Maca-Meyer, A Montejo-de-Garcini, A Aguirre-Jaime, L Pérez-Méndez, C Casanova
Respiratory Medicine 2008
Association between genetic variants of IL-1β, IL-6 and TNF-α cytokines and cognitive performance in the elderly general population of the MEMO-study
BT Baune, G Ponath, M Rothermundt, O Riess, H Funke, K Berger
Psychoneuroendocrinology 2008
Polymorphisms of cytokine and innate immunity genes and GVHD
AM Dickinson, E Holler
Best Practice & Research Clinical Haematology 2008
Multiple Organ Dysfunction Syndrome in Children With Sepsis: Role of Genetic Factors
O Liangos, BL Jaber
Seminars in Nephrology 2008
Is the interleukin-6 haplotype a prognostic factor for sciatica?
J Karppinen, I Daavittila, N Noponen, M Haapea, S Taimela, H Vanharanta, L Ala-Kokko, M Männikkö
European Journal of Pain 2008
Association of Interleukin-6 Gene Polymorphisms with Bone Mineral Density in Mexican Women
JJ Magaña, R Gómez, B Cisneros, L Casas, M Valdés-Flores
Archives of Medical Research 2008
Polymorphisms of the Interleukin-6 Gene Promoter and Abdominal Aortic Aneurysm
L Smallwood, R Allcock, F Bockxmeer, N Warrington, LJ Palmer, B Iacopetta, PE Norman
European Journal of Vascular and Endovascular Surgery 2008
Genetic polymorphisms and the fate of the transplanted organ
B Krüger, B Schröppel, BT Murphy
Transplantation Reviews 2008
Selected markers of cardiovascular disease in a population exposed to arsenic from drinking water
Z Bošnjak, S Ćavar, T Klapec, M Milić, M Klapec-Basar, M Toman
Environmental Toxicology and Pharmacology 2008
Clinical Impact of Cytokine and Growth Factor Genetic Polymorphisms in Thoracic Organ Transplantation
DM Girnita, SA Webber, A Zeevi
Clinics in Laboratory Medicine 2008
The Impact of Immune Gene Polymorphisms in Kidney and Liver Transplantation
P Nickerson
Clinics in Laboratory Medicine 2008
Surveillance biologique des patients transplantés rénaux : vers une prévision des complications associées à l’immunosuppression ?
P Saas, C Courivaud, J Bamoulid, F Garnache-Ottou, E Seilles, D Ducloux
Annales Pharmaceutiques Françaises 2008
A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population
A Benrick, P Jirholt, I Wernstedt, M Gustafsson, J Scheller, AL Eriksson, J Borén, T Hedner, C Ohlsson, T Härd, S Rose-John, JO Jansson
Regulatory Peptides 2008
Interleukin 6 −174(G&gt;C) gene polymorphism is related to celiac disease and autoimmune thyroiditis coincidence in diabetes type 1 children
M Myśliwiec, J Myśliwska, K Zorena, A Balcerska, E Malinowska, P Wiśniewski
Diabetes Research and Clinical Practice 2008
Synergistic effects of the polymorphisms in the PAI-1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease
B Sarecka, I Zak, J Krauze
Clinical Biochemistry 2008
Molecular epidemiology, cancer-related symptoms, and cytokines pathway
CC Reyes-Gibby, X Wu, M Spitz, R Kurzrock, M Fisch, E Bruera, S Shete
The Lancet Oncology 2008
Cerebral Small Vessel Disease: Genetic Risk Assessment for Prevention and Treatment
A Lam, MA Hamilton-Bruce, J Jannes, SA Koblar
Molecular diagnosis & therapy 2008
IL-6 as a biomarker of ischemic cerebrovascular disease
VP Moreno, D Subirá, E Meseguer, P Llamas
Biomarkers in Medicine 2008
Interleukin-6 Polymorphism is Associated with Chorioamnionitis and Neonatal Infections in Preterm Infants
M Reiman, H Kujari, E Ekholm, H Lapinleimu, L Lehtonen, L Haataja
The Journal of Pediatrics 2008
Interactions of interleukin-6 gene polymorphisms with calcium intake and physical activity on bone mass in pre-menarche Chinese girls
X Li, GP He, B Zhang, YM Chen, YX Su
Osteoporosis International 2008
IL6 (-174) and TNFA (-308) promoter polymorphisms are associated with systemic creatine kinase response to eccentric exercise
C Yamin, JA Duarte, JM Oliveira, O Amir, M Sagiv, N Eynon, M Sagiv, RE Amir
European Journal of Applied Physiology 2008
Vorstellungen zur Pathogenese der juvenilen idiopathischen Arthritis
T Niehues, O Feyen, T Telieps
Zeitschrift für Rheumatologie 2008
Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment
SJ Bull, P Huezo-Diaz, EB Binder, JF Cubells, G Ranjith, C Maddock, C Miyazaki, N Alexander, M Hotopf, AJ Cleare, S Norris, E Cassidy, KJ Aitchison, AH Miller, CM Pariante
Molecular Psychiatry 2008
IL6 gene-wide haplotype is associated with susceptibility to acute lung injury
C Flores, SF Ma, K Maresso, MS Wade, J Villar, JG Garcia
Translational Research 2008
Serum Interleukin-6 Levels, Not Genotype, Correlate With Coronary Plaque Complexity
LT Kuo, NI Yang, WJ Cherng, S Verma, MJ Hung, SY Wang, M Liu, S Chen, CH Wang
International Heart Journal 2008
Identification of a novel regulatory region in the interleukin-6 gene promoter
JM Samuel, D Kelberman, AJ Smith, SE Humphries, P Woo
Cytokine 2008
Genetic Polymorphisms Impact the Risk of Acute Rejection in Pediatric Heart Transplantation: A Multi-Institutional Study:
DM Girnita, MM Brooks, SA Webber, GJ Burckart, R Ferrell, G Zdanowicz, S DeCroo, L Smith, R Chinnock, C Canter, L Addonizio, D Bernstein, JK Kirklin, S Ranganathan, D Naftel, AL Girnita, A Zeevi
Transplantation 2008
Cytokine gene polymorphisms and cytokine levels in pulmonary tuberculosis
P Selvaraj, K Alagarasu, M Harishankar, M Vidyarani, DN Rajeswari, PR Narayanan
Cytokine 2008
Genetic variants of IL6 gene promoter influence on C-reactive protein levels but are not associated with susceptibility to invasive pulmonary aspergillosis in haematological patients
J Sainz, E Pérez, S Gómez-Lopera, E López-Fernández, L Moratalla, S Oyonarte, M Jurado
Cytokine 2008
Correlation between interleukin-6 promoter and C-reactive protein (CRP) polymorphisms and CRP levels with the Mainz Severity Score Index for Fabry disease
G Altarescu, G Chicco, C Whybra, S Delgado-Sanchez, N Sharon, M Beck, D Elstein
Journal of Inherited Metabolic Disease 2008
A familial analysis of aggressive periodontitis - clinical and genetic findings
L Nibali, N Donos, PM Brett, M Parkar, T Ellinas, M Llorente, GS Griffiths
Journal of Periodontal Research 2008
Interleukin-6-174 Genotype, Periodontal Disease and Adverse Pregnancy Outcomes: A Pilot Study
M Dashash, J Nugent, P Baker, D Tansinda, F Blinkhorn
Journal of Clinical Immunology 2008
Comprehensive association study of genetic variants in the IL-1 gene family in systemic juvenile idiopathic arthritis
CJ Stock, EM Ogilvie, JM Samuel, M Fife, CM Lewis, P Woo
Genes and Immunity 2008
Association of IL-6 gene polymorphism with the outcome of allogeneic haematopoietic stem cell transplantation in Czech patients
Z Ambruzova, F Mrazek, L Raida, E Faber, J Onderkova, E Kriegova, K Indrak, M Petrek
International Journal of Immunogenetics 2008
Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis
CJ Nile, RC Read, M Akil, GW Duff, AG Wilson
Arthritis & Rheumatism 2008
‘Deep phenotyping’: characterizing populations in the era of genomics and systems biology:
RP Tracy
Current Opinion in Lipidology 2008
Do inflammatory cytokine genes confer susceptibility to diabetic nephropathy?
S Maeda
Kidney International 2008
Association between −174 G/C Promoter Polymorphism of the Interleukin-6 Gene and Progression of Prostate Cancer in North Indian Population
P Kesarwani, DK Ahirwar, A Mandhani, RD Mittal
DNA and Cell Biology 2008
The -1082 interleukin-10 polymorphism is associated with acute respiratory failure after major trauma: A prospective cohort study
O Schroeder, KM Schulte, J Schroeder, A Ekkernkamp, RA Laun
Surgery 2008
Comparison of serum levels of inflammatory markers and allelic variant of interleukin-6 in patients with acute coronary syndrome and stable angina pectoris:
O Ozdemir, F Gundogdu, S Karakelleoglu, S Sevimli, I Pirim, M Acikel, S Arslan, S Serdar
Coronary Artery Disease 2008
Cytokine Gene Polymorphisms in Heavy Drinkers With and Without Decompensated Liver Disease: A Case-Control Study
D Gleeson, MP Bradley, J Jones, RJ Peck, SK Bond, MD Teare, GW Duff
The American Journal of Gastroenterology 2008
Association of interleukin-6 (IL-6) haplotypes with plaque-induced gingivitis in children
LI Holla, K Musilova, J Vokurka, L Klapusová, P Pantuckova, M Kukletova, L Kukla, V Znojil
Acta Odontologica Scandinavica 2008
Non-HLA genetics and predicting outcome in HSCT
AM Dickinson
International Journal of Immunogenetics 2008
Interleukin-6 gene variation in Spanish patients with immunoglobulin-A deficiency
R López-Mejías, A Martínez, N Pozo, M Fernández-Arquero, A Ferreira, E Urcelay, G Fontán, EG de la Concha, C Núñez
Human Immunology 2008
A critical assessment of adverse pregnancy outcome and periodontal disease
G Wimmer, BL Pihlstrom
Journal of Clinical Periodontology 2008
Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study
U Vogel, J Christensen, H Wallin, S Friis, BA Nexø, O Raaschou-Nielsen, K Overvad, A Tjønneland
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2008
Genetic association of cytokine DNA polymorphisms with head and neck cancer
Z Serefoglou, C Yapijakis, E Nkenke, E Vairaktaris
Oral Oncology 2008
Association of Interleukin 6 Promoter Polymorphism (-174G/C) with IL-6 Level and Outcome in Severe Sepsis
O Sabeļnikovs, L Ñikitina-Zaķe, I Vanags
Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences 2008
Cytokine gene polymorphisms in periodontal disease: a meta-analysis of 53 studies including 4178 cases and 4590 controls
GK Nikolopoulos, NL Dimou, SJ Hamodrakas, PG Bagos
Journal of Clinical Periodontology 2008
Interleukin promoter polymorphisms and prognosis in colorectal cancer
S Wilkening, B Tavelin, F Canzian, K Enquist, R Palmqvist, A Altieri, G Hallmans, K Hemminki, P Lenner, A Forsti
Carcinogenesis 2008
Correlation between polymorphisms at interleukin-6 but not at interleukin-10 promoter and the risk of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis in Brazilian individuals
SR Gadelha, LC Alcântara, GC Costa, AX Acosta, D Rios, S Kashima, DT Covas, B Galvão-Castro
Journal of Medical Virology 2008
TNF, IFNG, IL6, IL10 and TGFB1 gene polymorphisms in South and Southeast Brazil
JE Visentainer, AM Sell, GC da Silva, AD Cavichioli, DS Franceschi, SR Lieber, CA de Souza
International Journal of Immunogenetics 2008
Vaccination, a human model of inflammation, activates systemic inflammation but does not trigger proinflammatory gene expression in adipose tissue
M Ekström, P Eriksson, P Tornvall
Journal of Internal Medicine 2008
Lack of Associations Between Several Polymorphisms in Cytokine Genes and the Risk of Chronic Obstructive Pulmonary Diseases in Taiwan
MH Hsieh, IW Chong, JJ Hwang, CH Lee, CK Ho, ML Yu, CT Huang, CY Lee, MT Wu, DC Christiani
The Kaohsiung Journal of Medical Sciences 2008
Gene expression polymorphisms of interleukins-1β, -4, -6, -8, -10, and tumor necrosis factors-α, -β: regression analysis of their effect upon oral squamous cell carcinoma
E Vairaktaris, C Yapijakis, Z Serefoglou, D Avgoustidis, E Critselis, S Spyridonidou, A Vylliotis, S Derka, S Vassiliou, E Nkenke, E Patsouris
Journal of Cancer Research and Clinical Oncology 2008
The interleukin-6 gene and critical illness: Is inflammatory gene variation the key to personalized medicine in the intensive care unit?*:
JD Christie
Critical Care Medicine 2008
Interleukin-6 Polymorphisms Are Associated With Pathogenic Bacteria in Subjects With Periodontitis
L Nibali, MS Tonetti, D Ready, M Parkar, PM Brett, N Donos, F D'Aiuto
Journal of Periodontology 2008
Transforming growth factor- 1 869T/C, but not interleukin-6 -174G/C, polymorphism associates with hypertension in rheumatoid arthritis
VF Panoulas, KM Douglas, JP Smith, A Stavropoulos-Kalinoglou, GS Metsios, P Nightingale, GD Kitas
Rheumatology 2008
Evaluation of serum resistin levels in patients with ocular and non-ocular Behçet’s disease
FN Yalçindag, A Yalçindag, F Batioglu, O Çaglayan, Ü Kisa, Ö Özdemir
Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2008
Association between the -174 G/C promoter polymorphism of the interleukin-6 gene and cardiovascular disease risk factors in Brazilian older women
AC Tonet, M Karnikowski, CF Moraes, L Gomes, MG Karnikowski, C Córdova, OT Nóbrega
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] 2008
Interleukin-6 (IL-6) and receptor (IL6-R) gene haplotypes associate with amniotic fluid protein concentrations in preterm birth
DR Velez, SJ Fortunato, SM Williams, R Menon
Human Molecular Genetics 2008
The effect of IL6 -174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN study
J Shen, DK Arnett, P Pérez-Martínez, LD Parnell, CQ Lai, JM Peacock, JE Hixson, MY Tsai, RJ Straka, PN Hopkins, JM Ordovás
Journal of lipid research 2008
Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
BK Pedersen, MA Febbraio
Physiological reviews 2008
Biomarkers of Inflammation and MRI-Defined Small Vessel Disease of the Brain: The Cardiovascular Health Study
M Fornage, YA Chiang, ES O'Meara, BM Psaty, AP Reiner, DS Siscovick, RP Tracy, WT Longstreth
Stroke; a journal of cerebral circulation 2008
Imunossenescência: a relação entre leucócitos, citocinas e doenças crônicas
AC Tonet, O de Tolêdo Nóbrega
Revista Brasileira de Geriatria e Gerontologia 2008
Polymorphisms Cyclooxygenase-2 -765G>C and Interleukin-6 -174G>C Are Associated with Serum Inflammation Markers in a High Cardiovascular Risk Population and Do Not Modify the Response to a Mediterranean Diet Supplemented with Virgin Olive Oil or Nuts
D Corella, JI González, M Bulló, P Carrasco, O Portolés, J Díez-Espino, MI Covas, V Ruíz-Gutierrez, E Gómez-Gracia, F Arós, M Fiol, MC Herrera, JM Santos, G Sáez, R Lamuela, C Lahoz, E Vinyoles, E Ros, R Estruch
The Journal of nutrition 2008
A comprehensive review of the genetics of juvenile idiopathic arthritis
S Prahalad, DN Glass
Pediatric Rheumatology 2008
Primer on the Rheumatic Diseases
JH Klippel, JH Stone, LJ Crofford, PH White
2008
Infectious Diseases in the Pediatric Intensive Care Unit
S Nadel
2008
Association of Serum Interleukin-6 Concentration with a Functional IL6 −6331T>C Polymorphism
AJ Smith, F DAiuto, J Palmen, JA Cooper, J Samuel, S Thompson, J Sanders, N Donos, L Nibali, D Brull, P Woo, SE Humphries
Clinical chemistry 2008
The Influence of Tumor Necrosis Factor-α −308 G/A and IL-6 −174 G/C on Pain and Analgesia Response in Lung Cancer Patients Receiving Supportive Care
CC Reyes-Gibby, BE Osta, MR Spitz, H Parsons, R Kurzrock, X Wu, S Shete, E Bruera
Cancer epidemiology, biomarkers & prevention 2008
Correlation between interleukin-6 promoter and C-reactive protein (CRP) polymorphisms and CRP levels with the Mainz Severity Score Index for Fabry disease.
Altarescu G, Chicco G, Whybra C, Delgado-Sanchez S, Sharon N, Beck M, Elstein D
Journal of Inherited Metabolic Disease 2008
Interleukin-6 -174 genotype, periodontal disease and adverse pregnancy outcomes: a pilot study.
Dashash M, Nugent J, Baker P, Tansinda D, Blinkhorn F
Journal of Clinical Immunology 2008
Pathophysiology of acute graft-versus-host disease: recent advances
Y Sun, I Tawara, T Toubai, P Reddy
Translational Research 2007
IL6 genotypes and colon and rectal cancer
ML Slattery, RK Wolff, JS Herrick, BJ Caan, JD Potter
Cancer causes & control : CCC 2007
Advances in the understanding of acute graft- versus -host disease: Review
ES Morris, GR Hill
British Journal of Haematology 2007
Gene Polymorphisms of TNF-α−308, IL-10−1082, IL-6−174, and IL-1RaVNTR Related to Susceptibility and Severity of Rheumatic Heart Disease
A Settin, H Abdel-Hady, R El-Baz, I Saber
Pediatric Cardiology 2007
Juvenile rheumatoid arthritis
DS Kim
Korean Journal of Pediatrics 2007
Obesity and polymorphisms in genes regulating human adipose tissue
I Dahlman, P Arner
International Journal of Obesity 2007
Association of interleukin-6 and interleukin-10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status
I Marinou, J Healy, D Mewar, DJ Moore, MC Dickson, MH Binks, DS Montgomery, K Walters, AG Wilson
Arthritis & Rheumatism 2007
Juvenile idiopathic arthritis
A Ravelli, A Martini
The Lancet 2007
Haematopoietic stem cell transplantation: can our genes predict clinical outcome?
AM Dickinson, JL Harrold, H Cullup
Expert Reviews in Molecular Medicine 2007
Genetic susceptibility to total hip arthroplasty failure: a preliminary study on the influence of matrix metalloproteinase 1, interleukin 6 polymorphisms and vitamin D receptor
MH Malik, F Jury, A Bayat, WE Ollier, PR Kay
Annals of the rheumatic diseases 2007
Interleukin-6 expression and gene polymorphism are associated with severity of periodontal disease in a sample of Brazilian individuals
PR Moreira, PM Lima, KO Sathler, SA Imanishi, JE Costa, RS Gomes, KJ Gollob, WO Dutra
Clinical & Experimental Immunology 2007
The impact of interleukin-6 promoter -597/-572/-174genotype on interleukin-6 production after lipopolysaccharide stimulation
M Müller-Steinhardt, B Ebel, C Härtel
Clinical & Experimental Immunology 2007
Genetic susceptibility to lymphoma
CF Skibola, JD Curry, A Nieters
Haematologica 2007
Association of cytokine gene polymorphism with susceptibility and clinical types of leprosy
A Settin, S Nassar, A Abdel-Latif, R Elbaz, S El-Mongy, A Hassan, A Hassan
International journal of health sciences 2007
Alcohol consumption, interleukin-6 and apolipoprotein E genotypes, and concentrations of interleukin-6 and serum amyloid P in older adults
KJ Mukamal, NS Jenny, RP Tracy, DS Siscovick
The American journal of clinical nutrition 2007
Personalized Nutrition: Nutritional Genomics as a Potential Tool for Targeted Medical Nutrition Therapy
S Vakili, MA Caudill
Nutrition Reviews 2007
Investigation of functional gene polymorphisms interleukin-1β, interleukin-6, interleukin-10 and tumor necrosis factor in individuals with oral lichen planus
GM Xavier, AR de Sá, AL Guimarães, TA da Silva, RS Gomez
Journal of Oral Pathology & Medicine 2007
Influence of cytokine genes polymorphisms on long-term outcome in renal transplantation
B Breulmann, C Bantis, M Siekierka, C Blume, S Aker, N Kuhr, B Grabensee, K Ivens
Clinical Transplantation 2007
The role of interleukin-6 in insulin resistance, body fat distribution and energy balance
M Hoene, C Weigert
Obesity Reviews 2007
Genetic variation in the interleukin-6 gene in relation to risk and outcomes in acute coronary syndrome
A Mälarstig, L Wallentin, A Siegbahn
Thrombosis Research 2007
The IL6 −174G/C polymorphism and sudden infant death syndrome
SH Opdal, TO Rognum
Human Immunology 2007
Risk assessment in haematopoietic stem cell transplantation: Pre–transplant patient and donor factors: non-HLA genetics
AM Dickinson
Best Practice & Research Clinical Haematology 2007
Interleukin-6 Polymorphisms, Helicobacter pylori Infection in Adult Brazilian Patients with Chronic Gastritis and Gastric Adenocarcinoma
LL Gatti, RR Burbano, M Zambaldi-Tunes, RW de-Lábio, PP de Assumpção, MA Cardoso-Smith, SL Marques-Payão
Archives of Medical Research 2007
Interleukin-6 gene variants and the risk of sepsis development in children
J Michalek, P Svetlikova, M Fedora, M Klimovic, L Klapacova, D Bartosova, H Hrstkova, JA Hubacek
Human Immunology 2007
Efficacy of thalidomide in systemic onset juvenile rheumatoid arthritis
M García-Carrasco, S Fuentes-Alexandro, RO Escárcega, J Rojas-Rodriguez, LE Escobar
Joint Bone Spine 2007
Interleukin-6 gene polymorphism and faster progression to end-stage renal failure in chronic glomerulonephritis
M Buraczynska, L Jozwiak, P Ksiazek, E Borowicz, P Mierzicki
Translational Research 2007
Impact of serum levels and gene polymorphism of cytokines on chronic hepatitis C infection
TY Chen, YS Hsieh, TT Wu, SF Yang, CJ Wu, GJ Tsay, HL Chiou
Translational Research 2007
IL-6-174 C/G polymorphism in the gastroenteropancreatic neuroendocrine tumors (GEP-NETs)
MC Berković, M Jokić, J Marout, S Radošević, V Zjačić-Rotkvić, S Kapitanović
Experimental and Molecular Pathology 2007
Handbook of Systemic Autoimmune Diseases
M Karmegam, RJ Quigg
Handbook of Systemic Autoimmune Diseases 2007
Common genetic factors for depression and cardiovascular disease
B Bondy
Dialogues in clinical neuroscience 2007
Sepsis
JM O’Brien, NA Ali, SK Aberegg, E Abraham
The American Journal of Medicine 2007
Systemic onset juvenile idiopathic arthritis: update on pathogenesis and treatment
LJ Mirkinson, IM Katona
Expert Review of Clinical Immunology 2007
Effect of the interleukin-6 C174G gene polymorphism on treatment of acute and chronic hepatitis C in human immunodeficiency virus coinfected patients
J Nattermann, M Vogel, T Berg, M Danta, B Axel, C Mayr, R Bruno, C Tural, G Klausen, B Clotet, T Lutz, F Grünhage, M Rausch, HD Nischalke, K Schewe, B Bienek, G Haerter, T Sauerbruch, JK Rockstroh, U Spengler,
Hepatology 2007
Arthrites juvéniles idiopathiques
C Job-Deslandre
EMC - Appareil locomoteur 2007
No evidence for a role of the proximal IL-6 G/C -174 single nucleotide polymorphism in Italian patients with systemic sclerosis
L Beretta, A Santaniello, F Cappiello, M Barili, R Scorza
Journal of Cellular and Molecular Medicine 2007
Association of interleukin (IL)-4 intron-3 and IL-6 −174 G/C gene polymorphism with susceptibility to end-stage renal disease
RD Mittal, PK Manchanda
Immunogenetics 2007
Interleukin-6 and atrial fibrillation in patients with coronary artery disease: data from the Heart and Soul Study
GM Marcus, MA Whooley, DV Glidden, L Pawlikowska, JG Zaroff, JE Olgin
American Heart Journal 2007
Cytokine gene variants and venous thrombotic risk in the BRATROS (BRAZILIAN THROMBOSIS STUDY)
F Pieroni, DM Lourenço, VM Morelli, FH Maffei, MA Zago, RF Franco
Thrombosis Research 2007
Interleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal Muscle
S Glund, A Deshmukh, YC Long, T Moller, HA Koistinen, K Caidahl, JR Zierath, A Krook
Diabetes 2007
Impact of Common Type 2 Diabetes Risk Polymorphisms in the DESIR Prospective Study
M Vaxillaire, J Veslot, C Dina, C Proenca, S Cauchi, G Charpentier, J Tichet, F Fumeron, M Marre, D Meyre, B Balkau, P Froguel
Diabetes 2007
Frequency distribution of cytokine gene polymorphisms in the healthy North Indian population
G Kaur, CC Rapthap, N Kumar, S Kumar, S Neolia, NK Mehra
Tissue Antigens 2007
Cytokine gene polymorphism and progression of renal and cardiovascular diseases
M Rao, C Wong, P Kanetsky, M Girndt, P Stenvinkel, M Reilly, DS Raj
Kidney International 2007
No association of interleukin-6 gene polymorphism (-174 G/C) with premature coronary artery disease in a Turkish cohort:
C Sekuri, FS Cam, A Sagcan, E Ercan, I Tengiz, E Alioglu, A Berdeli
Coronary Artery Disease 2007
Interleukin-6 gene promoter –174G/C polymorphism and insulin resistance: a pilot study
P Tretjakovs, G Latkovskis, N Licis, D Juhnevica, A Jurka, I Bormane, JI Aivars, A Stifts, V Pirags
Clinical Chemistry and Laboratory Medicine 2007
Long-term prognosis after coronary bypass surgery depends on interleukin 6 polymorphism and past acute infections
J Myśliwska, J Więckiewicz, Ł Hak, J Siebert, J Rogowski, K Szyndler, A Myśliwski
International Journal of Cardiology 2007
The extent of periodontal disease and the IL-6 −174 genotype as determinants of serum IL-6 level
T Raunio, M Nixdorf, M Knuuttila, R Karttunen, O Vainio, T Tervonen
Journal of Clinical Periodontology 2007
Association between plasma IL-6, the IL6 −174G>C gene variant and the metabolic syndrome in type 2 diabetes mellitus
JW Stephens, SJ Hurel, GD Lowe, A Rumley, SE Humphries
Molecular Genetics and Metabolism 2007
Genetic Polymorphisms of Inflammatory Cytokines and Liver Fibrosis Progression Due To Recurrent Hepatitis C
E Falleti, C Fabris, P Toniutto, E Fontanini, A Cussigh, M Caldato, E Rossi, D Bitetto, R Minisini, C Smirne, M Pirisi
Journal of Interferon & Cytokine Research 2007
Autoinflammatory syndromes with a dermatological perspective
N KANAZAWA, F FURUKAWA
The Journal of Dermatology 2007
Association of polymorphisms of cytokine genes (IL1B, IL1RN, TNFA, LTA, IL6, IL8, and IL10) with chronic obstructive pulmonary disease
KV Danilko, GF Korytyna, LZ Akhmadishina, DG Yanbaeva, SZ Zagidullin, TV Victorova
Molecular Biology 2007
Polymorphisms in cytokine genes influence long-term survival differently in elderly male and female patients
T Cederholm, M Persson, P Andersson, P Stenvinkel, L Nordfors, J Madden, I Vedin, B Wretlind, RF Grimble, J Palmblad
Journal of Internal Medicine 2007
CARDIOVASCULAR AND SURVIVAL PARADOXES IN DIALYSIS PATIENTS: Genetics and Reverse Epidemiology Among Patients on Chronic Hemodialysis: REVERSE EPIDEMIOLOGY AMONG PATIENTS ON CHRONIC HEMODIALYSIS
VS Balakrishnan, M Rao
Seminars in Dialysis 2007
Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes
U Vogel, J Christensen, H Wallin, S Friis, BA Nexø, A Tjønneland
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2007
Pro-inflammatory genetic profiles in subjects with peripheral arterial occlusive disease and critical limb ischemia
A Flex, E Gaetani, F Angelini, A Sabusco, C Chillà, G Straface, F Biscetti, P Pola, JJ Castellot, R Pola
Journal of Internal Medicine 2007
Biomarkers for cancer cachexia: is there also a genetic component to cachexia?
BH Tan, DA Deans, RJ Skipworth, JA Ross, KC Fearon
Supportive Care in Cancer 2007
IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study
JD Walston, MD Fallin, M Cushman, L Lange, B Psaty, N Jenny, W Browner, R Tracy, P Durda, A Reiner
Human Genetics 2007
Association of CD14, IL1B, IL6, IL10 and TNFA functional gene polymorphisms with symptomatic dental abscesses
AR de Sá, PR Moreira, GM Xavier, I Sampaio, E Kalapothakis, WO Dutra, RS Gomez
International Endodontic Journal 2007
TNF-alpha, TNF-beta, IL-6, IL-10, PECAM-1 and the MPO Inflammatory Gene Polymorphisms in Osteosarcoma:
ID Oliveira, AS Petrilli, MH Tavela, MA Zago, SR de Toledo
Journal of Pediatric Hematology/Oncology 2007
Specific gene expression profiles in systemic juvenile idiopathic arthritis
EM Ogilvie, A Khan, M Hubank, P Kellam, P Woo
Arthritis & Rheumatism 2007
Role of IL-6, TNF-A and LT-A variants in the modulation of the clinical expression of plaque-induced gingivitis
C Scapoli, E Mamolini, L Trombelli
Journal of Clinical Periodontology 2007
Interleukin 6 Variable Number of Tandem Repeats (VNTR) Gene Polymorphism in Centenarians
C Capurso, V Solfrizzi, A D'Introno, AM Colacicco, SA Capurso, C Semeraro, A Capurso, F Panza
Annals of Human Genetics 2007
Investigation of functional gene polymorphisms: IL-1B, IL-6 and TNFA in benign migratory glossitis in Brazilian individuals: Cytokine gene polymorphisms and benign migratory glossitis
AL Guimarães, JF Correia-Silva, MG Diniz, GM Xavier, MC Horta, RS Gomez
Journal of Oral Pathology & Medicine 2007
Single nucleotide polymorphisms of cytokine genes in the healthy Slovak population
J Javor, M Bucova, S Ferencik, H Grosse-Wilde, M Buc
International Journal of Immunogenetics 2007
Polymorphisms in the CD14 and IL-6 genes associated with periodontal disease
T Tervonen, T Raunio, M Knuuttila, R Karttunen
Journal of Clinical Periodontology 2007
Prospective study of interaction between alcohol, NSAID use and polymorphisms in genes involved in the inflammatory response in relation to risk of colorectal cancer
U Vogel, J Christensen, M Dybdahl, S Friis, RD Hansen, H Wallin, BA Nexø, O Raaschou-Nielsen, PS Andersen, K Overvad, A Tjønneland
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2007
Interleukin-6 −174 promoter polymorphism does not influence IL-6 production after LPS and IL-1β stimulation in human umbilical cord vein endothelial cells
P Kiszel, V Makó, Z Prohászka, L Cervenak
Cytokine 2007
Influence of the IL-6 −572C>G polymorphism on inflammatory markers according to cigarette smoking in Korean healthy men
KK Shin, Y Jang, SJ Koh, JS Chae, OY Kim, S Park, D Choi, DJ Shin, HJ Kim, JH Lee
Cytokine 2007
Efficacité de la thalidomide dans les arthrites chroniques juvéniles à début systémique
M García-Carrasco, S Fuentes-Alexandro, RO Escárcega, J Rojas-Rodriguez, LE Escobar
Revue du Rhumatisme 2007
Association of TGF-β1 codon 25 (G915C) polymorphism with hepatitis C virus infection
FA Pereira, NN da Silva, IF Rodart, TM Carmo, DC Lemaire, MG Reis
Journal of Medical Virology 2007
The interleukin-6 (IL6)–174 G/C promoter genotype is associated with the presence of septic shock and the ex vivo secretion of IL6
JJ Tischendorf, E Yagmur, D Scholten, D Vidacek, A Koch, R Winograd, AM Gressner, C Trautwein, HE Wasmuth, F Lammert
International Journal of Immunogenetics 2007
Impact of interleukin 6 −174G>C polymorphism on obesity-related metabolic disorders in people with excess in body weight
E Goyenechea, D Parra, JA Martínez
Metabolism 2007
IL2 and TNFA Gene Polymorphisms and the Risk of Graft-versus-Host Disease after Allogeneic Haematopoietic Stem Cell Transplantation
DO Viel, LT Tsuneto, CR Sossai, SR Lieber, SB Marques, AC Vigorito, FJ Aranha, KA de Eid, GB Oliveira, EC Miranda, CA de Souza, JE Visentainer
Scandinavian Journal of Immunology 2007
Genetic susceptibility and body mass in childhood cancer survivors
JA Ross
Pediatric Blood & Cancer 2007
Renal Allograft Immune Response Is Influenced by Patient and Donor Cytokine Genotypes
A Canossi, A Piazza, E Poggi, G Ozzella, MD Rocco, F Papola, G Iaria, D Adorno
Transplantation Proceedings 2007
Association and interaction of the TNF-alpha gene with other pro- and anti-inflammatory cytokine genes and HLA genes in patients with type 1 diabetes from North India
R Kumar, R Goswami, S Agarwal, N Israni, SK Singh, R Rani
Tissue Antigens 2007
Screening the human serum proteome for genotype–phenotype associations: An analysis of theIL6 –174G>C polymorphism
CM Hegedus, CF Skibola, P Bracci, EA Holly, MT Smith
PROTEOMICS 2007
Lack of association between genetic polymorphisms in cytokine genes and disease expression in patients with hereditary non-polyposis colorectal cancer
BA Talseth, C Meldrum, J Suchy, G Kurzawski, J Lubinski, RJ Scott
Scandinavian Journal of Gastroenterology 2007
Elevated IL‐6 levels in the synovial fluid of osteoarthritis patients stem from plasma cells
F Doß, J Menard, M Hauschild, HJ Kreutzer, T Mittlmeier, M MüllerSteinhardt, B Müller
Scandinavian Journal of Rheumatology 2007
Interleukin-4 Promoter Polymorphisms: A Genetic Prognostic Factor for Survival in Metastatic Renal Cell Carcinoma
T Kleinrath, C Gassner, P Lackner, M Thurnher, R Ramoner
Journal of Clinical Oncology 2007
Association of cytokine genetic polymorphism with hepatites B infection evolution in adult patients
CS Ribeiro, JE Visentainer, RA Moliterno
Memórias do Instituto Oswaldo Cruz 2007
Single-nucleotide polymorphisms in selected cytokine genes and risk of adult glioma
AV Brenner, MA Butler, SS Wang, AM Ruder, N Rothman, PA Schulte, SJ Chanock, HA Fine, MS Linet, PD Inskip
Carcinogenesis 2007
Gene Polymorphisms and the Prevalence of Key Periodontal Pathogens
L Nibali, DR Ready, M Parkar, PM Brett, M Wilson, MS Tonetti, GS Griffiths
Journal of dental research 2007
The Interleukin-6 inflammation pathway from cholesterol to aging – Role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases
S Omoigui
Immunity & Ageing 2007
Effects of the Interaction between Interleukin-6-634C/G Polymorphism and Smoking on Serum C-Reactive Protein Concentrations
Y SAIJO, E YOSHIOKA, T FUKUI, M KAWAHARADA, F SATA, H SATO, R KISHI
Hypertension Research 2007
Are Promoter Polymorphisms of Interleukin 6 Ready to Be Applied in Genetic Markers of Cardiovascular Diseases?
S IWAMOTO
Hypertension Research 2007
Cytokines in Human Health
RV House, J Descotes
2007
Bone Marrow and Stem Cell Transplantation
M Beksac
2007
Interleukin-6 Genetic Variability and Adiposity: Associations in Two Prospective Cohorts and Systematic Review in 26,944 Individuals
L Qi, C Zhang, RM van Dam, FB Hu
The Journal of clinical endocrinology and metabolism 2007
Candidate Gene Genotypes, Along with Conventional Risk Factor Assessment, Improve Estimation of Coronary Heart Disease Risk in Healthy UK Men
SE Humphries, JA Cooper, PJ Talmud, GJ Miller
Clinical chemistry 2007
IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study.
Walston JD, Fallin MD, Cushman M, Lange L, Psaty B, Jenny N, Browner W, Tracy R, Durda P, Reiner A
Human Genetics 2007
Mature-onset obesity in interleukin-1 receptor I knockout mice
MC García, I Wernstedt, A Berndtsson, M Enge, M Bell, O Hultgren, M Horn, B Ahrén, S Enerback, C Ohlsson, V Wallenius, JO Jansson
Diabetes 2006
Cytokine gene polymorphisms in retinal detachment patients with and without proliferative vitreoretinopathy: a preliminary study
MR Ruiz-Colmenares, JC Jimeno, JA Adrados, JJ Orriols, MI Fernández
Acta Ophthalmologica Scandinavica 2006
Lack of association of interleukin-6 and interleukin-8 gene polymorphisms in Chinese patients with systemic lupus erythematosus
CM Huang, AP Huo, CH Tsai, CL Chen, FJ Tsai
Journal of Clinical Laboratory Analysis 2006
The role of cardiopulmonary fitness and its genetic influences on surgical outcomes
JT Lee, EJ Chaloner, SJ Hollingsworth
British Journal of Surgery 2006
Concordance of functional in vitro data and epidemiological associations in complex disease genetics
JP Ioannidis, FK Kavvoura
Genetics in Medicine 2006
Case?control study in basal cell carcinoma of the skin: single nucleotide polymorphisms in three interleukin promoters pre-analysed in pooled DNA
S Wilkening, K Hemminki, P Rudnai, E Gurzau, K Koppova, R Kumar, A Försti
British Journal of Dermatology 2006
Polymorphisms of interleukin-6, hepatic lipase and calpain-10 genes, and preeclampsia
T Saarela, M Hiltunen, S Helisalmi, S Heinonen, M Laakso
European Journal of Obstetrics & Gynecology and Reproductive Biology 2006
Influence of the −308 TNF-α and −174 IL-6 polymorphisms on lipid profile in Mexican subjects
I Parra-Rojas, B Ruíz-Madrigal, E Martínez-López, A Panduro
Hereditas 2006
Genetic and environmental contributions to plasma C-reactive protein and interleukin-6 levels – a study in twins
MA Wörns, A Victor, PR Galle, T Höhler
Genes and Immunity 2006
Variants Associated with Common Disease Are Not Unusually Differentiated in Frequency across Populations
KE Lohmueller, MM Mauney, D Reich, JM Braverman
The American Journal of Human Genetics 2006
Blood and synovial fluid cytokine signatures in patients with juvenile idiopathic arthritis: a cross-sectional study
W Jager, EP Hoppenreijs, NM Wulffraat, LR Wedderburn, W Kuis, BJ Prakken
Annals of the rheumatic diseases 2006
Novel IL10 gene family associations with systemic juvenile idiopathic arthritis
MS Fife, A Gutierrez, EM Ogilvie, CJ Stock, JM Samuel, W Thomson, LF Mack, CM Lewis, P Woo
Arthritis Research & Therapy 2006
Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review
SP Balasubramanian, IA Azmy, SE Higham, AG Wilson, SS Cross, A Cox, NJ Brown, MW Reed
BMC Cancer 2006
The interleukin-6 gene -174G>C and -572G>C promoter polymorphisms are related to cerebral aneurysms
L Morgan, J Cooper, H Montgomery, N Kitchen, SE Humphries
Journal of neurology, neurosurgery, and psychiatry 2006
IL-10, IL-6 and CD14 polymorphisms and sepsis outcome in ventilated very low birth weight infants
RJ Baier, J Loggins, K Yanamandra
BMC Medicine 2006
Analysis of G(-174)C IL-6 polymorphism and plasma concentrations of inflammatory markers in patients with type 2 diabetes and peripheral arterial disease
M Libra, SS Signorelli, Y Bevelacqua, PM Navolanic, V Bevelacqua, J Polesel, R Talamini, F Stivala, MC Mazzarino, G Malaponte
Journal of clinical pathology 2006
Innate immunity SNPs are associated with risk for severe sepsis after burn injury
RC Barber, LY Chang, BD Arnoldo, GF Purdue, JL Hunt, JW Horton, CC Aragaki
Clinical medicine & research 2006
Polycystic Ovarian Syndrome
KA Khan, S Stas, LR Kurukulasuriya
Journal of the CardioMetabolic Syndrome 2006
The IL - 6 promoter polymorphism is associated with disease activity and disability in systemic sclerosis
RS Cornateanu, C Mihai, S Balan, R Ionescu, E Moldoveanu
Journal of Cellular and Molecular Medicine 2006
Interleukin 6: from bench to bedside
N Nishimoto, T Kishimoto
Nature Clinical Practice Rheumatology 2006
Risk of adverse post-transplant events after kidney allograft transplantation as predicted by CTLA-4 +49 and TNF-α −308 single nucleotide polymorphisms: A preliminary study
K Gendzekhadze, P Rivas-Vetencourt, RF Montano
Transplant Immunology 2006
Interleukin-6–174 G&gt;C polymorphism affects the association between IL-6 plasma levels and insulin resistance in type 2 diabetic patients
R Testa, F Olivieri, AR Bonfigli, C Sirolla, M Boemi, F Marchegiani, M Marra, S Cenerelli, R Antonicelli, A Dolci, G Paolisso, C Franceschi
Diabetes Research and Clinical Practice 2006
Polymorphism of interferon–gamma gene at position +874 and clinical characteristics of chronic hepatitis C
CY Dai, WL Chuang, MY Hsieh, LP Lee, NJ Hou, SC Chen, ZY Lin, MY Hsieh, LY Wang, JF Tsai, WY Chang, ML Yu
Translational Research 2006
Pharmacogenetics: Progress, pitfalls and clinical potential for coronary heart disease
SE Humphries, A Hingorani
Vascular Pharmacology 2006
Common Polymorphism in Interleukin 6 Influences Survival of Women with Ovarian and Peritoneal Carcinoma
R Garg, M Wollan, V Galic, R Garcia, BA Goff, HJ Gray, E Swisher
Gynecologic Oncology 2006
Polymorphisms in the interleukin 6 and transforming growth factor β1 gene and risk of dementia
M Oijen, PP Arp, FJ de Jong, A Hofman, PJ Koudstaal, AG Uitterlinden, MM Breteler
Neuroscience Letters 2006
Genetic Predisposition and Renal Allograft Failure: Implication of Non-HLA Genetic Variants
F Khan, S Agrawal, S Agrawal
Molecular diagnosis & therapy 2006
Disparate Distribution of 16 Candidate Single Nucleotide Polymorphisms Among Racial and Ethnic Groups of Pediatric Heart Transplant Patients:
DM Girnita, SA Webber, R Ferrell, GJ Burckart, MM Brooks, KK McDade, R Chinnock, C Canter, L Addonizio, D Bernstein, JK Kirklin, AL Girnita, A Zeevi
Transplantation 2006
The Autoimmune Diseases
I Kang, J Craft
The Autoimmune Diseases 2006
The Human Calcium-Sensing Receptor and Interleukin-6 Genes are Associated with Bone Mineral Density in Chinese
YB WANG, JJ GUO, YJ LIU, FY DENG, DK JIANG, HW DENG
Acta Genetica Sinica 2006
Interleukin-6 gene polymorphism -174G/C influences plasma lipid levels in women
S Henningsson, A Håkansson, L Westberg, F Baghaei, R Rosmond, G Holm, A Ekman, H Nissbrandt, E Eriksson
Obesity 2006
Impaired regulation of immune responses in cognitive decline and Alzheimer’s disease: lessons from genetic association studies
M Chiappelli, E Tumini, E Porcellini, F Licastro
Expert Review of Neurotherapeutics 2006
Interleukin-6 involvement in brain arteriovenous malformations
Y Chen, L Pawlikowska, JS Yao, F Shen, W Zhai, AS Achrol, MT Lawton, PY Kwok, GY Yang, WL Young
Annals of Neurology 2006
Interleukin (IL)–12, IL-2, and IL-6 Gene Polymorphisms in Takayasu’s Arteritis from Turkey
G Saruhan-Direskeneli, M Bıçakçıgil, V Yılmaz, S Kamalı, K Aksu, I Fresko, N Akkoç, S Kiraz, HT Özer, E Tunç, E Yücel, Y Karaarslan, FA Uyar, E Doganavşargil, M Inanc, H Direskeneli
Human Immunology 2006
IL6 Gene Promoter Polymorphisms and Type 2 Diabetes: Joint Analysis of Individual Participants' Data From 21 Studies
C Huth, IM Heid, C Vollmert, C Gieger, H Grallert, JK Wolford, B Langer, B Thorand, N Klopp, YH Hamid, O Pedersen, T Hansen, V Lyssenko, L Groop, C Meisinger, A Doring, H Lowel, W Lieb, C Hengstenberg, W Rathmann, S Martin, JW Stephens, H Ireland, H Mather, GJ Miller, HM Stringham, M Boehnke, J Tuomilehto, H Boeing, M Mohlig, J Spranger, A Pfeiffer, I Wernstedt, A Niklason, A Lopez-Bermejo, JM Fernandez-Real, RL Hanson, L Gallart, J Vendrell, A Tsiavou, E Hatziagelaki, SE Humphries, HE Wichmann, C Herder, T Illig
Diabetes 2006
Susceptibility to JRA/JIA: complementing general autoimmune and arthritis traits
JD Phelan, SD Thompson, DN Glass
Genes and Immunity 2006
Dissociation of inflammatory markers and natural killer cell activity in major depressive disorder
JL Pike, MR Irwin
Brain, Behavior, and Immunity 2006
Cytokine Gene Polymorphisms Are Not Associated With Bronchiolitis Obliterans Syndrome or Survival After Lung Transplant
LD Snyder, MG Hartwig, T Ganous, RD Davis, WF Herczyk, NL Reinsmoen, DA Schwartz, SM Palmer
The Journal of Heart and Lung Transplantation 2006
The −174G/C interleukin-6 promoter polymorphism influences the development of macular oedema following uncomplicated phacoemulsification surgery
I Masood, A Negi, SA Vernon, P Comeglio, AH Child
Eye 2006
Weight regain after slimming induced by an energy-restricted diet depends on interleukin-6 and peroxisome-proliferator-activated-receptor-γ2 gene polymorphisms
E Goyenechea, MD Parra, JA Martínez
British Journal of Nutrition 2006
Increase in interleukin-6 following arterial injury is related to insulin resistance, the ?174G?C polymorphism and complex plaque morphology
SP Marso, JA House, PJ Hopkins
International Journal of Immunogenetics 2006
Hostility and pain are related to inflammation in older adults
JE Graham, TF Robles, JK Kiecolt-Glaser, WB Malarkey, MG Bissell, R Glaser
Brain, Behavior, and Immunity 2006
Interleukin-6 −174 G/C promoter polymorphism and effects of fenofibrate and simvastatin on inflammatory markers in hypercholesterolemic patients:
DP Potaczek, A Undas, M Celinska-Lowenhoff, A Szczeklik
Blood Coagulation & Fibrinolysis 2006
Association of Sudden Infant Death Syndrome With VEGF and IL-6 Gene Polymorphisms
M Dashash, V Pravica, IV Hutchinson, AJ Barson, DB Drucker
Human Immunology 2006
The association of cytokine gene polymorphisms with febrile non-hemolytic transfusion reaction in multitransfused patients
M Addas-Carvalho, TS Salles, ST Saad
Transfusion Medicine 2006
Proinflammatory cytokine gene polymorphisms among Hashimoto's thyroiditis patients
RH Chen, CT Chang, WC Chen, CH Tsai, FJ Tsai
Journal of Clinical Laboratory Analysis 2006
Recovery of CD4+ T Cells in HIV Patients With a Stable Virologic Response to Antiretroviral Therapy Is Associated With Polymorphisms of Interleukin-6 and Central Major Histocompatibility Complex Genes:
S Fernandez, AA Rosenow, IR James, SG Roberts, RC Nolan, MA French, P Price
Journal of acquired immune deficiency syndromes (1999) 2006
Cytokine gene polymorphisms can alter the effect of Bacillus Calmette–Guérin (BCG) immunotherapy
B Basturk, I Yavascaoglu, B Oral, G Göral, B Oktay
Cytokine 2006
Interleukin-6 response to isokinetic exercise in elite athletes: relationships to adrenocortical function and to mechanical and myoelectric fatigue
MA Minetto, A Rainoldi, M Gazzoni, GP Ganzit, L Saba, P Paccotti
European Journal of Applied Physiology 2006
IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4
H Grallert, C Huth, M Kolz, C Meisinger, C Herder, K Strassburger, G Giani, HE Wichmann, J Adamski, T Illig, W Rathmann
Experimental Gerontology 2006
Genetic Analysis of Juvenile Rheumatoid Arthritis: Approaches to Complex Traits
S Prahalad
Current Problems in Pediatric and Adolescent Health Care 2006
IL6 G-174C Associated With Sudden Infant Death Syndrome in a Caucasian Australian Cohort
SM Moscovis, AE Gordon, OM Madani, M Gleeson, RJ Scott, J Roberts-Thomson, ST Hall, DM Weir, A Busuttil, CC Blackwell
Human Immunology 2006
No Association Between Selected Candidate Gene Polymorphisms and Severe Chronic Periodontitis
JC Wohlfahrt, T Wu, JS Hodges, JE Hinrichs, BS Michalowicz
Journal of Periodontology 2006
Role of Single Nucleotide Polymorphisms of Cytokine Genes in Spontaneous Preterm Delivery
EM Speer, DA Gentile, A Zeevi, G Pillage, D Huo, DP Skoner
Human Immunology 2006
Interleukin-6 g.−174G>C Promoter Polymorphism Is Associated with Obesity in the EPIC-Potsdam Study*
K Klipstein-Grobusch, M Möhlig, J Spranger, K Hoffmann, FU Rodrigues, AM Sharma, S Klaus, AF Pfeiffer, H Boeing
Obesity 2006
Systemic juvenile idiopathic arthritis: diagnosis, management, and outcome
P Woo
Nature clinical practice. Rheumatology 2006
Common Genetic Vulnerability to Depressive Symptoms and Coronary Artery Disease: A Review and Development of Candidate Genes Related to Inflammation and Serotonin:
JM McCaffery, N Frasure-Smith, MP Dubé, P Théroux, GA Rouleau, QL Duan, F Lespérance
Psychosomatic medicine 2006
Interleukin-6 polymorphisms and the risk of cervical cancer
NN de Souza, S Brenna, F Campos, K Syrjanen, E Baracat, I Silva
International Journal of Gynecological Cancer 2006
Th1 and Th2 cytokine gene polymorphisms in two indigenous ethnic groups in Iran
A Amirzargar, M Sadeghi, F Khosravi, S Dianat, M Naroueynejad, MH Nicknam, N Hatmi, B Ansaripour, B Moradi, B Nikbin
International Journal of Immunogenetics 2006
Fibrinogen and CRP in Israeli families: Genetic and environmental sources of concentrations and longitudinal changes
Y Friedlander, JD Kark, R Sinnreich, RP Tracy, DS Siscovick
Atherosclerosis 2006
Relation between common polymorphisms in genes related to inflammatory response and colorectal cancer
G Theodoropoulos, I Papaconstantinou, E Felekouras, N Nikiteas, P Karakitsos, D Panoussopoulos, AC Lazaris, E Patsouris, J Bramis, M Gazouli
World journal of gastroenterology : WJG 2006
Systemic Inflammation in COPD: Is Genetic Susceptibility a Key Factor?
DG Yanbaeva, MA Dentener, EC Creutzberg, EF Wouters
COPD 2006
Cytokine Gene Polymorphisms in Multifactorial Conditions
T Laitinen
Cytokine Gene Polymorphisms in Multifactorial Conditions 2006
The Genetic Determinants of Renal Impairment Following Cardiac Surgery
RB Yates, M Stafford-Smith
Seminars in cardiothoracic and vascular anesthesia 2006
Genetic variation in IL6 gene and type 2 diabetes: tagging-SNP haplotype analysis in large-scale case–control study and meta-analysis
L Qi, RM van Dam, JB Meigs, JA Manson, D Hunter, FB Hu
Human Molecular Genetics 2006
Reduced stress- and cold-induced increase in energy expenditure in interleukin-6-deficient mice
I Wernstedt, A Edgley, A Berndtsson, J Fäldt, G Bergström, V Wallenius, JO Jansson
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2006
CD16 + monocytes produce IL-6, CCL2, and matrix metalloproteinase-9 upon interaction with CX3CL1-expressing endothelial cells
P Ancuta, J Wang, D Gabuzda
Journal of leukocyte biology 2006
Principles of Molecular Medicine
MS Runge, C Patterson
2006
Genetic polymorphisms of inflammatory cytokines and myocardial infarction in the elderly
F Olivieri, R Antonicelli, M Cardelli, F Marchegiani, L Cavallone, E Mocchegiani, C Franceschi
Mechanisms of Ageing and Development 2006
Associations between Interleukin-6 Genetic Polymorphisms and Levels of Autoantibodies to 60-kDa Heat-Shock Proteins
P Kiszel, G Füst, T Pessi, M Hurme, Z Prohászka
Human Heredity 2006
Interleukin-6 response to isokinetic exercise in elite athletes: relationships to adrenocortical function and to mechanical and myoelectric fatigue.
Minetto MA, Rainoldi A, Gazzoni M, Ganzit GP, Saba L, Paccotti P
European Journal of Applied Physiology 2006
Proinflammatory cytokine gene polymorphisms among Hashimoto's thyroiditis patients.
Chen RH, Chang CT, Chen WC, Tsai CH, Tsai FJ
Journal of Clinical Laboratory Analysis 2006
Influence of IL-6, COL1A1, and VDR gene polymorphisms on bone mineral density in Crohn's disease
CE Todhunter, A Sutherland-Craggs, SA Bartram, PT Donaldson, AK Daly, RM Francis, JC Mansfield, NP Thompson
Gut 2005
The use of anakinra in juvenile arthritis
A Reiff
Current Rheumatology Reports 2005
Genetic variation associated with preterm birth: A HuGE review
KS Crider, N Whitehead, RM Buus
Genetics in Medicine 2005
The interleukin-6 −174 single nucleotide polymorphism: Cervical protein production and the risk of preterm delivery
WE Jamie, RK Edwards, RJ Ferguson, P Duff
American Journal of Obstetrics and Gynecology 2005
Genetic determinants of blood pressure regulation
JB Marteau, M Zaiou, G Siest, S Visvikis-Siest
Journal of Hypertension 2005
Interaction of polymorphisms in the genes encoding interleukin-6 and estrogen receptor beta on the susceptibility to Parkinson's disease
A H�kansson, L Westberg, S Nilsson, S Buervenich, A Carmine, B Holmberg, O Sydow, L Olson, B Johnels, E Eriksson, H Nissbrandt
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2005
TNF-α-, TNF-β-, IL-6-, and IL-10-promoter polymorphisms in patients with chronic obstructive pulmonary disease
C Seifart, A Dempfle, A Plagens, U Seifart, U Clostermann, B Müller, C Vogelmeier, P Wichert
Tissue Antigens 2005
Gene variants for osteoporosis and their pleiotropic effects in aging
SL Ferrari, R Rizzoli
Molecular Aspects of Medicine 2005
Open label phase II trial of single, ascending doses of MRA in Caucasian children with severe systemic juvenile idiopathic arthritis: proof of principle of the efficacy of IL-6 receptor blockade in this type of arthritis and demonstration of prolonged clinical improvement
P Woo, N Wilkinson, AM Prieur, T Southwood, V Leone, P Livermore, H Wythe, D Thomson, T Kishimoto
Arthritis Research & Therapy 2005
Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the -174 IL-6 G/C polymorphism in children
A Sawczenko, O Azooz, J Paraszczuk, M Idestrom, NM Croft, MO Savage, AB Ballinger, IR Sanderson
Proceedings of the National Academy of Sciences 2005
Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study
H Bukulmez, M Fife, M Tsoras, SD Thompson, NA Twine, P Woo, JM Olson, RC Elston, DN Glass, RA Colbert
Arthritis Research & Therapy 2005
Pro- and anti-inflammatory cytokine gene polymorphism profiles in Bulgarian multiple sclerosis patients
S Mihailova, M Ivanova, A Mihaylova, L Quin, O Mikova, E Naumova
Journal of Neuroimmunology 2005
Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association
A Nieters, JM Yuan, CL Sun, ZQ Zhang, J Stoehlmacher, S Govindarajan, MC Yu
Cancer 2005
Associations of the −174 G/C Interleukin-6 Gene Promoter Polymorphism with Serum Interleukin 6 and Mortality in the Elderly
G Ravaglia, P Forti, F Maioli, M Chiappelli, P Dolzani, M Martelli, M Bianchin, E Mariani, L Bolondi, F Licastro
Biogerontology 2005
The interleukin-6 −174 promoter polymorphism is associated with extrapulmonary bacterial dissemination in Streptococcus pneumoniae infection
B Schaaf, J Rupp, M Müller-Steinhardt, J Kruse, F Boehmke, M Maass, P Zabel, K Dalhoff
Cytokine 2005
Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia
T Lehrnbecher, T Bernig, M Hanisch, U Koehl, M Behl, D Reinhardt, U Creutzig, T Klingebiel, SJ Chanock, D Schwabe
Leukemia 2005
Polymorphism of host response genes: Implications in the pathogenesis and treatment of acute renal failure
BL Jaber, BJ Pereira, JV Bonventre, VS Balakrishnan
Kidney International 2005
Role of interaction between variants in the PPARG and interleukin-6 genes on obesity related metabolic risk factors
M Barbieri, MR Rizzo, M Papa, R Acampora, LD Angelis, F Olivieri, F Marchegiani, C Franceschi, G Paolisso
Experimental Gerontology 2005
TNF-α −308G/A and IL-6 −174 G/C polymorphisms in the Turkish pediatric stroke patients
ZC Karahan, G Deda, T Sipahi, AH Elhan, N Akar
Thrombosis Research 2005
Interleukin-6 gene polymorphism and risk of osteoarthritis of the hip: a case–control study
E Pola, P Papaleo, R Pola, E Gaetani, F Tamburelli, L Aulisa, C Logroscino
Osteoarthritis and Cartilage 2005
NeuroImmune Biology
R Solana, G Pawelec
NeuroImmune Biology 2005
Genetic polymorphisms in sepsis:
MK Dahmer, A Randolph, S Vitali, MW Quasney
Pediatric Critical Care Medicine 2005
Targeting the interleukin-6 receptor: A new treatment for systemic juvenile idiopathic arthritis?
F Benedetti, A Martini
Arthritis & Rheumatism 2005
Artritis juveniles idiopáticas
P Quartier, AM Prieur
EMC - Tratado de Medicina 2005
Differentiation-dependent expression and mitogenic action of interleukin-6 in human colon carcinoma cells: Relevance for tumour progression
W Brozek, G Bises, T Girsch, HS Cross, HE Kaiser, M Peterlik
European Journal of Cancer 2005
Measuring Immunity
MT Stang, JH Yim
Measuring Immunity 2005
The biology, utilization, and attenuation of C-reactive protein in cardiovascular disease: Part I
A Armani, RC Becker
American Heart Journal 2005
Cytokine gene polymorphisms in Japanese patients with hepatitis B virus infection—association between TGF-β1 polymorphisms and hepatocellular carcinoma
K Migita, S Miyazoe, Y Maeda, M Daikoku, S Abiru, T Ueki, K Yano, S Nagaoka, T Matsumoto, K Nakao, K Hamasaki, H Yatsuhashi, H Ishibashi, K Eguchi
Journal of Hepatology 2005
The pharmacogenetic impact of inflammatory genes on bladder cancer recurrence
J Gu, HB Grossman, CP Dinney, X Wu
Pharmacogenomics 2005
Genetic polymorphisms and sepsis
J Arcaroli, MB Fessler, E Abraham
Shock 2005
Juvenile Idiopathic Arthritis
JE Weiss, NT Ilowite
Pediatric Clinics of North America 2005
IL-6 and IL-10 promoter gene polymorphisms do not associate with the susceptibility for multiple myeloma
G Mazur, K Bogunia-Kubik, T Wróbel, L Karabon, M Polak, K Kuliczkowski, A Lange
Immunology Letters 2005
Effect of the Interleukin-6 (−174) G/C Promoter Polymorphism on Adiponectin and Insulin Sensitivity
X Yang, PA Jansson, F Pellmé, M Laakso, U Smith
Obesity research 2005
Cytokine gene polymorphisms as potential risk and protective factors in renal cell carcinoma
B Baştürk, İ Yavaşçaoğlu, H Vuruşkan, G Göral, B Oktay, HB Oral
Cytokine 2005
Genetic variations in IL6 associate with intervertebral disc disease characterized by sciatica
N Noponen-Hietala, I Virtanen, R Karttunen, S Schwenke, E Jakkula, H Li, R Merikivi, S Barral, J Ott, J Karppinen, L Ala-Kokko
PAIN 2005
Interleukin-6 (IL-6) − 373 A9T11 allele is associated with reduced susceptibility to chronic periodontitis in Japanese subjects and decreased serum IL-6 level
Y Komatsu, H Tai, JC Galicia, Y Shimada, M Endo, K Akazawa, K Yamazaki, H Yoshie
Tissue Antigens 2005
IL-6 and IL-10 Promoter Gene Polymorphisms of Patients and Donors of Allogeneic Sibling Hematopoietic Stem Cell Transplants Associate With the Risk of Acute Graft-Versus-Host Disease
L Karabon, B Wysoczanska, K Bogunia-Kubik, K Suchnicki, A Lange
Human Immunology 2005
Detection of a single nucleotide polymorphism in the IL-6 promoter region of ancient nuclear DNA
LA Larcombe, P Nickerson, RD Hoppa, C Matheson
Infection, Genetics and Evolution 2005
The genetics of stroke:
L Morgan, SE Humphries
Current Opinion in Lipidology 2005
Interleukin-6 Genetic Polymorphism and Chinese Major Depression
CJ Hong, YW Yu, TJ Chen, SJ Tsai
Neuropsychobiology 2005
Genetic and clinical factors influence the baseline permeability of the peritoneal membrane
G Gillerot, E Goffin, C Michel, P Evenepoel, WV Biesen, M Tintillier, P Stenvinkel, O Heimburger, B Lindholm, L Nordfors, A Robert, O Devuyst
Kidney International 2005
Interleukin-6 Polymorphism: A Genetic Risk Factor for Cardiac Transplant Related Coronary Vasculopathy?
CG Densem, M Ray, IV Hutchinson, N Yonan, NH Brooks
The Journal of Heart and Lung Transplantation 2005
A comparison of methods for determining genotypes at the tumour necrosis factor-alpha -308, interleukin (IL)-1beta +3953, IL-6 -174 and IL-10 -1082/-819/-592 polymorphic loci
MJ Bown, S Weston, T Horsburgh, ML Nicholson, PR Bell, RD Sayers
International Journal of Immunogenetics 2005
Interleukin-6-174-genotype, sepsis and cerebral injury in very low birth weight infants
W Göpel, C Härtel, P Ahrens, I König, E Kattner, E Kuhls, H Küster, J Möller, D Müller, B Roth, H Segerer, C Wieg, E Herting
Genes and Immunity 2005
Physical Function and Its Response to Exercise: Associations With Cytokine Gene Variation in Older Adults With Knee Osteoarthritis
BJ Nicklas, J Mychaleckyj, S Kritchevsky, S Palla, LA Lange, EM Lange, SP Messier, D Bowden, M Pahor
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2005
Frequencies of the common promoter polymorphisms in cytokine genes in a Polish population
M Kurzawski, A Pawlik, B Czerny, L Domanski, J Rozanski, M Drozdzik
International Journal of Immunogenetics 2005
Relationship between cytokine gene polymorphisms and graft-versus-host disease after allogeneic stem cell transplantation in a Brazilian population
JE Visentainer, SR Lieber, LB Persoli, SB Marques, AC Vigorito, FJ Aranha, KA de Eid, GB Oliveira, EC Miranda, L Bragotto, CA de Souza
Cytokine 2005
Non-HLA immunogenetics in hematopoietic stem cell transplantation
AM Dickinson, D Charron
Current Opinion in Immunology 2005
Polymorphisms in the interferon-γ gene at position +874 in patients with chronic hepatitis C treated with high-dose interferon-α and ribavirin
CY Dai, WL Chuang, WY Chang, SC Chen, LP Lee, MY Hsieh, NJ Hou, ZY Lin, MY Hsieh, LY Wang, ML Yu
Antiviral Research 2005
Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: The cardiovascular health study
AP Reiner, P Diehr, WS Browner, SE Humphries, NS Jenny, M Cushman, RP Tracy, J Walston, T Lumley, AB Newman, LH Kuller, BM Psaty
Atherosclerosis 2005
Cytokine Gene Polymorphisms and Genetic Association with Coeliac Disease in the Finnish Population
N Woolley, K Mustalahti, M Maki, J Partanen
Scandinavian Journal of Immunology 2005
IL6, IL10 and TGFB1 gene polymorphisms in coeliac disease: differences between DQ2 positive and negative patients
JA Garrote, E Arranz, E Gómez-González, AJ León, C Farré, C Calvo, D Bernardo, L Fernández-Salazar, A Blanco-Quirós
Allergologia et Immunopathologia 2005
Association tests of interleukin-6 (IL-6) and type II tumor necrosis factor receptor (TNFR2) genes with bone mineral density in Caucasians using a re-sampling approach
P Xiao, PY Liu, Y Lu, YF Guo, DH Xiong, LH Li, RR Recker, HW Deng
Human Genetics 2005
Effect of genetic variability on the inflammatory response to periodontal infection
L Shapira, A Wilensky, DF Kinane
Journal of Clinical Periodontology 2005
C-reactive protein (+1444C>T) polymorphism influences CRP response following a moderate inflammatory stimulus
F D’Aiuto, JP Casas, T Shah, SE Humphries, AD Hingorani, MS Tonetti
Atherosclerosis 2005
A Case-Control Study in IL6 and TGFB1 Gene Polymorphisms and Recurrent Spontaneous Abortion in Southern Brazilian Patients
R Linsingen, EP Bompeixe, MG Bicalho
American Journal of Reproductive Immunology 2005
Lack of association between pro-inflammatory cytokine (IL-6, IL-8 and TNF-alpha) gene polymorphisms and Graves' disease
RH Chen, WC Chen, TY Wang, CH Tsai, FJ Tsai
International Journal of Immunogenetics 2005
Polymorphisms of interleukin-1 gene complex, IL6 and tumour necrosis factor genes in chronic idiopathic neutropenia of adults
M Addas-Carvalho, EV Paula, CS Lima, ST Saad
Annals of Hematology 2005
Increased Cytokine Secretion in Patients with Failed Implants Compared with Patients with Primary Implants:
J Waddell, KP Pritzker, EL Boynton
Clinical Orthopaedics and Related Research® 2005
Association ofSLC11A1 (NRAMP1) with persistent oligoarticular and polyarticular rheumatoid factor-negative juvenile idiopathic arthritis in Finnish patients: Haplotype analysis in Finnish families
JA Runstadler, H S�il�, A Savolainen, M Leirisalo-Repo, K Aho, E Tuomilehto-Wolf, J Tuomilehto, MF Seldin
Arthritis & Rheumatism 2005
The interleukin-6 −174 G>C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients
R Antonicelli, F Olivieri, M Bonafè, L Cavallone, L Spazzafumo, F Marchegiani, M Cardelli, A Recanatini, P Testarmata, M Boemi, G Parati, C Franceschi
International Journal of Cardiology 2005
Clearance of hepatitis C virus is not associated with single nucleotide polymorphisms in the IL-1, -6, or -10 genes
EJ Minton, D Smillie, P Smith, S Shipley, MW McKendrick, DC Gleeson, JC Underwood, C Cannings, AG Wilson
Human Immunology 2005
The influence of gender on human innate immunity
SD Imahara, S Jelacic, CE Junker, GE O'Keefe
Surgery 2005
Effect of IL-6 promoter polymorphism on incidence and outcome in Hodgkin's lymphoma
P Cordano, A Lake, L Shield, GM Taylor, FE Alexander, PR Taylor, J White, RF Jarrett
British Journal of Haematology 2005
The –174G/C Polymorphism of the Interleukin 6 Gene Is a Hallmark of Lacunar Stroke and Not Other Ischemic Stroke Phenotypes
A Chamorro, M Revilla, V Obach, M Vargas, AM Planas
Cerebrovascular Diseases 2005
Mechanisms of nitric oxide-mediated intestinal barrier failure in necrotizing enterocolitis
JS Upperman, D Potoka, A Grishin, D Hackam, R Zamora, HR Ford
Seminars in Pediatric Surgery 2005
Interleukin-6 gene polymorphism in renal transplant patients with and without gingival overgrowth
M Drozdzik, M Kurzawski, A Drozdzik, K Kotrych, J Banach, A Pawlik
Journal of Clinical Periodontology 2005
Cytokine-Related Genotypic Differences in Peak Interleukin-6 Blood Levels of Patients with SIRS and Septic Complications:
E Watanabe, H Hirasawa, S Oda, H Shiga, K Matsuda, M Nakamura, R Abe, T Nakada
The Journal of trauma 2005
Nonassociation of Interleukin 4 intron 3 and 590 Promoter Polymorphisms with Bronchopulmonary Dysplasia for Ventilated Preterm Infants
HC Lin, BH Su, JS Chang, CM Hsu, CH Tsai, FJ Tsai
Biology of the Neonate 2005
Extremely high interleukin-6 blood levels and outcome in the critically ill are associated with tumor necrosis factor??? and interleukin-1???related gene polymorphisms*:
E Watanabe, H Hirasawa, S Oda, K Matsuda, M Hatano, T Tokuhisa
Critical Care Medicine 2005
Novel IL-6 haplotypes and disease association
MS Fife, EM Ogilvie, D Kelberman, J Samuel, A Gutierrez, SE Humphries, P Woo
Genes and Immunity 2005
Impact of genes related to immune tolerance and inflammation (tumour necrosis factor-α, interleukin-6) on blood pressure, protein excretion and oedema in pregnancy:
T Pfab, YP Chen, T Slowinski, CM Richter, M Godes, PC Arck, H Halle, B Hocher
Journal of Hypertension 2005
The Role of Cytokine Gene Polymorphisms in Determining Disease Susceptibility and Phenotype in Inflammatory Bowel Disease
MJ Cantor, P Nickerson, CN Bernstein
The American Journal of Gastroenterology 2005
Genetic association of cytokines polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in the Chinese
Lie-Ying Fan, Xiao-Qing Tu, Ye Zhu, Thomas Pfeiffer, Ralph Feltens, Winfried Stoecker, Ren-Qian Zhong
World journal of gastroenterology : WJG 2005
C-174G Polymorphism in the Promoter of the Interleukin-6 Gene Is Associated With Insulin Resistance
M Cardellini, L Perego, M D'Adamo, MA Marini, C Procopio, ML Hribal, F Andreozzi, S Frontoni, M Giacomelli, M Paganelli, AE Pontiroli, R Lauro, F Folli, G Sesti
Diabetes care 2005
Is puberty an accelerator of type 1 diabetes in IL6-174CC females?
Kathleen M Gillespie, Runa Nolsøe, Virginie M Betin, Ole P Kristiansen, Polly J Bingley, Thomas Mandrup-Poulsen, Edwin A M Gale
Diabetes 2005
Interleukin-6 and diabetes: the good, the bad, or the indifferent?
Ole P Kristiansen, Thomas Mandrup-Poulsen
Diabetes 2005
INTERLEUKIN-6 PROMOTER POLYMORPHISM AND LATE-ONSET ALZHEIMER's DISEASE IN THE FINNISH POPULATION
AM Koivisto, S Helisalmi, J Pihlajamäki, L Moilanen, J Kuusisto, M Laakso, M Hiltunen, K Keijo, T Hänninen, EL Helkala, K Kervinen, YA kesäniemi, H Soininen
Journal of Neurogenetics 2005
Polymorphisms in Inflammation Genes and Bladder Cancer: From Initiation to Recurrence, Progression, and Survival
D Leibovici, HB Grossman, CP Dinney, RE Millikan, S Lerner, Y Wang, J Gu, Q Dong, X Wu
Journal of Clinical Oncology 2005
Inflammatory markers and IL-6 polymorphism in peripheral arterial disease with and without diabetes mellitus
P Danielsson, L Truedsson, KF Eriksson, L Norgren
Vascular medicine (London, England) 2005
The immuno-inflammatory response to trauma
CC Tzioupis, S Katsoulis, N Manidakis, PV Giannoudis
Trauma 2005
The Interleukin-6 –174G/C Promoter Polymorphism Is Not Associated With Endometriosis in South Indian Women
M Bhanoori, KA Babu, M Deenadayal, S Kennedy, S Shivaji
Journal of the Society for Gynecologic Investigation 2005
Cytokine genotypes correlate with pain and radiologically defined joint damage in patients with juvenile rheumatoid arthritis
K Oen, PN Malleson, DA Cabral, AM Rosenberg, RE Petty, P Nickerson, M Reed
Rheumatology (Oxford, England) 2005
Does systemic-onset juvenile idiopathic arthritis belong under juvenile idiopathic arthritis?
AV Ramanan, AA Grom
Rheumatology (Oxford, England) 2005
Physical activity and modulation of systemic low-level inflammation
H Bruunsgaard
Journal of leukocyte biology 2005
Interleukin-6 −174G/C polymorphism and longevity: a follow-up study
M Hurme, T Lehtimäki, M Jylhä, PJ Karhunen, A Hervonen
Mechanisms of Ageing and Development 2005
Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes
YH Hamid, CS Rose, SA Urhammer, C Glmer, R Nolse, OP Kristiansen, T Mandrup-Poulsen, K Borch-Johnsen, T Jorgensen, T Hansen, O Pedersen
Diabetologia 2005
Cytokine Gene Polymorphisms in Patch‐stage Mycosis Fungoides
E Hodak, L Akerman, M David, T Klein, A Tambur, B Kfir, L Maron, J Sulkes
Acta Dermato Venereologica 2005
Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians
C Franceschi, F Olivieri, F Marchegiani, M Cardelli, L Cavallone, M Capri, S Salvioli, S Valensin, GD Benedictis, AD Iorio, C Caruso, G Paolisso, D Monti
Mechanisms of Ageing and Development 2005
Genes and outcome after aneurysmal subarachnoid haemorrhage
YM Ruigrok, AJ Slooter, A Bardoel, CJ Frijns, GJ Rinkel, C Wijmenga
Journal of Neurology 2005
Interleukin-6 genotype is associated with high-density lipoprotein cholesterol responses to exercise training
A Halverstadt, DA Phares, S Roth, RE Ferrell, AP Goldberg, JM Hagberg
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2005
Interaction between interleukin?6 and intercellular adhesion molecule?1 genes and Alzheimer?s disease risk
O Combarros, J Infante, J Llorca, N Pea, C Fernndez-Viadero, J Berciano
Journal of Neurology 2005
Single Nucleotide Polymorphisms in the Interleukin-6 Gene Associated with Blood Pressure and Atherosclerosis in a Japanese General Population
C TANAKA, T MANNAMI, K KAMIDE, S TAKIUCHI, Y KOKUBO, T KATSUYA, Y KAWANO, T MIYATA, T OGIHARA, H TOMOIKE
Hypertension Research 2005
Biology of Depression: From Novel Insights to Therapeutic Strategies
J Licinio, ML Wong
2005
Effect of genetic modifiers on cerebral lesions in Fabry disease
G Altarescu, DF Moore, R Schiffmann
Neurology 2005
Association tests of interleukin-6 (IL-6) and type II tumor necrosis factor receptor (TNFR2) genes with bone mineral density in Caucasians using a re-sampling approach.
Xiao P, Liu PY, Lu Y, Guo YF, Xiong DH, Li LH, Recker RR, Deng HW
Human Genetics 2005
Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases?
M Bennermo, C Held, S Stemme, CG Ericsson, A Silveira, F Green, P Tornvall
Clinical chemistry 2004
Cooperative influence of the interleukin-6 promoter polymorphisms -597, -572 and -174 on long-term kidney allograft survival
M Müller-Steinhardt, L Fricke, B Müller, B Ebel, H Kirchner, C Härtel
American Journal of Transplantation 2004
Non-HLA immunogenetic polymorphisms and the risk of complications after allogeneic hemopoietic stem-cell transplantation
C Mullighan, S Heatley, K Doherty, F Szabo, A Grigg, T Hughes, A Schwarer, J Szer, B Tait, B To, P Bardy
Transplantation 2004
Increased expression of IL-6 and RANK mRNA in human trabecular bone from fragility fracture of the femoral neck
H Tsangari, DM Findlay, JS Kuliwaba, GJ Atkins, NL Fazzalari
Bone 2004
Blasts from the past
PA Insel, S Kornfeld, PW Majerus, AR Marks, PA Marks, AS Relman, BF Scharschmidt, TP Stossel, AP Varki, SJ Weiss, JD Wilson
Journal of Clinical Investigation 2004
Innate immunity genes influence the severity of acute appendicitis
FA Rivera-Chavez, DL Peters-Hybki, RC Barber, GM Lindberg, I Jialal, RS Munford, GE O'Keefe
Annals of Surgery 2004
The IL-6 G-174C polymorphism may be associated with ischaemic stroke in patients without a history of hypertension
J Balding, WJ Livingstone, SJ Pittock, L Mynett-Johnson, T Ahern, A Hodgson, OP Smith
Irish Journal of Medical Science 2004
Role of cytokine gene polymorphism and hepatic transforming growth factor β1 expression in recurrent hepatitis C after liver transplantation
Z Ben-Ari, O Pappo, T Druzd, J Sulkes, T Klein, Z Samra, R Gadba, AR Tambur, R Tur-Kaspa, E Mor
Cytokine 2004
Genetic risk factors for stroke and carotid atherosclerosis: insights into pathophysiology from candidate gene approaches
SE Humphries, L Morgan
The Lancet Neurology 2004
Genomic polymorphisms in sepsis
MT Lin, TE Albertson
Critical Care Medicine 2004
Cytokine gene polymorphism and immunoregulation in periodontal disease
JJ Taylor, PM Preshaw, PT Donaldson
Periodontology 2000 2004
Cytokine gene polymorphisms in ischaemic heart disease: investigation using family-based tests of association
PG McGlinchey, MS Spence, CC Patterson, AR Allen, G Murphy, DA Savage, AP Maxwell, PP McKeown
Journal of Molecular Medicine 2004
Renovascular disease is associated with low producer genotypes of the anti-inflammatory cytokine interleukin-10
S George, XZ Ruan, C Navarrete, D Turner, M Reynard, P Sweny, G Hamilton, DC Wheeler, SH Powis, JF Moorhead, Z Varghese
Tissue Antigens 2004
Inflammatory bowel disease: the role of inflammatory cytokine gene polymorphisms
J Balding, WJ Livingstone, J Conroy, L Mynett-Johnson, DG Weir, N Mahmud, OP Smith
Mediators of Inflammation 2004
Elevated white cell count in acute coronary syndromes: relationship to variants in inflammatory and thrombotic genes
CE Byrne, A Fitzgerald, CP Cannon, DJ Fitzgerald, DC Shields
BMC Medical Genetics 2004
An interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes
JW Stephens, SJ Hurel, J Acharya, SE Humphries
Cardiovascular Diabetology 2004
The -174 G/C gene polymorphism in interleukin-6 is associated with an aggressive breast cancer phenotype
B Iacopetta, F Grieu, D Joseph
British Journal of Cancer 2004
Association of the G-174C Variant in the Interleukin-6 Promoter Region With Bone Loss and Fracture Risk in Older Women
SP Moffett, JM Zmuda, JA Cauley, KL Stone, MC Nevitt, KE Ensrud, TA Hillier, MC Hochberg, G Joslyn, P Morin, SR Cummings
Journal of Bone and Mineral Research 2004
Influence of Cytokine Gene Polymorphisms on Focal Segmental Glomerulosclerosis
C Bantis, PJ Heering, Y Luther, S Aker, N Kuhr, B Grabensee, K Ivens
American Journal of Nephrology 2004
Injury research in the genomic era
JP Cobb, GE O'Keefe
The Lancet 2004
Cytokine gene polymorphisms in hemodialysis patients: Association with comorbidity, functionality, and serum albumin
VS Balakrishnan, D Guo, M Rao, BL Jaber, H Tighiouart, RL Freeman, C Huang, AJ King, BJ Pereira
Kidney International 2004
Interactions of Interleukin-6 Promoter Polymorphisms With Dietary and Lifestyle Factors and Their Association With Bone Mass in Men and Women From the Framingham Osteoporosis Study
SL Ferrari, D Karasik, J Liu, S Karamohamed, AG Herbert, LA Cupples, DP Kiel
Journal of Bone and Mineral Research 2004
Advances in the genomics of allogeneic haemopoietic stem cell transplantation
CG Mullighan, PG Bardy
Drug Development Research 2004
Cytokine gene polymorphisms in endemic pemphigus foliaceus: a possible role for IL6 variants
NF Pereira, JA Hansen, MT Lin, VM Roxo, K Braun, ML Petzl-Erler
Cytokine 2004
An analysis of CTLA-4 and proinflammatory cytokine genes in Wegener's granulomatosis
Y Zhou, DR Huang, PL Paris, CS Sauter, KA Prock, GS Hoffman
Arthritis & Rheumatism 2004
Interleukin-6 promoter polymorphism: risk and pathology of Alzheimer's disease
Y Zhang, A Hayes, A Pritchard, U Thaker, M Haque, H Lemmon, J Harris, A Cumming, J Lambert, M Chartierharlin
Neuroscience Letters 2004
Mutations of Genes Involved in the Innate Immune System as Predictors of Sepsis in Very Low Birth Weight Infants
P Ahrens, E Kattner, B Köhler, C Härtel, J Seidenberg, H Segerer, J Möller, W Göpel
Pediatric Research 2004
Effect of enalapril and losartan on cytokines in patients with stable angina pectoris awaiting coronary artery bypass grafting and their interaction with polymorphisms in the interleukin-6 gene
J Trevelyan, DJ Brull, EW Needham, HE Montgomery, A Morris, RK Mattu
The American Journal of Cardiology 2004
Association between TNF-alpha and TGF-beta genotypes in infants and parental history of allergic rhinitis and asthma
DA Gentile, WJ Doyle, A Zeevi, J Howe-Adams, J Trecki, DP Skoner
Human Immunology 2004
Prognostic value of plasma interleukin-6 concentrations and the -174 G > C and -572 G > C promoter polymorphisms of the interleukin-6 gene in patients with acute myocardial infarction treated with thrombolysis
M Bennermo, C Held, F Green, LE Strandberg, CG Ericsson, LO Hansson, H Watkins, A Hamsten, P Tornvall
Atherosclerosis 2004
The IL-6 −174G>C polymorphism is associated with cardiovascular diseases and mortality in 80-year-old humans
H Bruunsgaard, L Christiansen, AN Pedersen, M Schroll, T Jørgensen, BK Pedersen
Experimental Gerontology 2004
Polymorphisms in cytokines and growth factor genes and their association with acute rejection and recurrence of hepatitis C virus disease in liver transplantation: Host genetic factors and outcomes after LTX
VR Mas, RA Fisher, DG Maluf, KJ Archer, MJ Contos, SA Mills, ML Shiffman, DS Wilkinson, L Oliveros, CT Garrett, A Ferreira-Gonzalez
Clinical Genetics 2004
C-reactive protein levels and common polymorphisms of the interleukin-1 gene cluster and interleukin-6 gene in patients with coronary heart disease
G Latkovskis, N Licis, U Kalnins
European Journal of Immunogenetics 2004
A common interleukin-6 gene promoter polymorphism influences the clinical characteristics of women with polycystic ovary syndrome
K Walch, C Grimm, R Zeillinger, JC Huber, F Nagele, LA Hefler
Fertility and Sterility 2004
The effect of recipient cytokine gene polymorphism on cardiac transplantation outcome
IS Gourley, D Denofrio, W Rand, S Desai, E Loh, M Kamoun
Human Immunology 2004
Association of transforming growth factor ?1 and tumor necrosis factor ? polymorphisms with anti-SSB/La antibody secretion in patients with primary Sj�gren's syndrome
JE Gottenberg, M Busson, P Loiseau, M Dourche, J Cohen-Solal, V Lepage, D Charron, C Miceli, J Sibilia, X Mariette
Arthritis & Rheumatism 2004
Candidate Gene Studies of Human Pain Mechanisms: Methods for Optimizing Choice of Polymorphisms and Sample Size
I Belfer, T Wu, A Kingman, RK Krishnaraju, D Goldman, MB Max
Anesthesiology 2004
A common functional variant in the interleukin-6 gene is associated with increased body mass index in subjects with type 2 diabetes mellitus
JW Stephens, SJ Hurel, JA Cooper, J Acharya, GJ Miller, SE Humphries
Molecular Genetics and Metabolism 2004
Clinical impact of cytokine gene polymorphisms in heart and lung transplantation
CT Holweg, W Weimar, AG Uitterlinden, CC Baan
The Journal of Heart and Lung Transplantation 2004
Cytokine Gene Polymorphisms in Recurrent Pregnancy Loss of Unknown Cause
N Prigoshin, M Tambutti, J Larriba, S Gogorza, R Testa
American Journal of Reproductive Immunology 2004
Promoter polymorphism of SLC11A1 (formerly NRAMP1) confers susceptibility to autoimmune type 1 diabetes mellitus in Japanese
K Takahashi, J Satoh, Y Kojima, K Negoro, M Hirai, Y Hinokio, Y Kinouchi, S Suzuki, N Matsuura, T Shimosegawa, Y Oka
Tissue Antigens 2004
Functional promoter region polymorphism of the proinflammatory chemokine IL-8 gene associates with Parkinson's disease in the Irish
OA Ross, C O'Neill, IM Rea, T Lynch, D Gosal, A Wallace, MD Curran, D Middleton, JM Gibson
Human Immunology 2004
HLA-DRB1 and -DQB1 alleles and gene polymorphisms of selected cytokines in systemic lupus erythematosus
A Hrycek, U Siekiera, P Cieślik, W Szkróbka
Rheumatology International 2004
Inflammatory mediators in the elderly
KS Krabbe, M Pedersen, H Bruunsgaard
Experimental Gerontology 2004
Single nucleotide polymorphisms in the promoter region of the interleukin-6 gene and the risk of recurrent pregnancy loss in japanese women
Y Saijo, F Sata, H Yamada, T Kondo, EH Kato, R Kishi
Fertility and Sterility 2004
Association of polymorphisms in Th1, Th2 cytokine genes with hayfever and atopy in a subsample of EPIC-Heidelberg
A Nieters, J Linseisen, N Becker
Cell 2004
Cytokine gene polymorphisms in idiopathic pulmonary fibrosis
RL Riha, IA Yang, GC Rabnott, AM Tunnicliffe, KM Fong, PV Zimmerman
Internal Medicine Journal 2004
Genetics of juvenile idiopathic arthritis: an update:
S Prahalad
Current Opinion in Rheumatology 2004
No association of interleukin-6 gene polymorphism (−174 G/C) with myocardial infarction or traditional cardiovascular risk factors
W Lieb, R Pavlik, J Erdmann, B Mayer, SR Holmer, M Fischer, A Baessler, C Hengstenberg, H Loewel, A Doering, GA Riegger, H Schunkert
International Journal of Cardiology 2004
The IL-6 Gene G-174C Polymorphism Related to Health Indices in Greek Primary School Children**
GV Dedoussis, Y Manios, DM Choumerianou, N Yiannakouris, DB Panagiotakos, K Skenderi, A Zampelas
Obesity 2004
Periodontitis and atherogenesis: causal association or simple coincidence?. A pilot intervention study
F D'Aiuto, M Parkar, G Andreou, PM Brett, D Ready, MS Tonetti
Journal of Clinical Periodontology 2004
Analysis of the Interleukin-6 Gene Promoter Polymorphisms in Czech Patients with Chronic Periodontitis
LI Holla, A Fassmann, A Stejskalová, V Znojil, J Vaněk, J Vacha
Journal of Periodontology 2004
Immunological markers contributing to successful aging in Bulgarians
E Naumova, A Mihaylova, M Ivanova, S Michailova, K Penkova, D Baltadjieva
Experimental Gerontology 2004
TNF-α, TGF-β, IL-10, IL-6, and INF-γ alleles among African Americans and Cuban Americans. Report of the ASHI minority workshops: Part IV
NL Delaney, V Esquenazi, DP Lucas, AA Zachary, MS Leffell
Human Immunology 2004
Auto-immuniteit en polymorfismen van het aangeboren en specifieke immuunsysteem
A Royen-Kerkhof, WL Pol, NM Sorge, EA Sanders, W Kuis
Tijdschrift voor kindergeneeskunde 2004
Immunoregulatory cytokine polymorphisms in Italian patients affected by paroxysmal nocturnal haemoglobinuria and aplastic anaemia
E Fermo, P Bianchi, W Barcellini, P Pedotti, C Boschetti, F Alfinito, A Cortelezzi, A Zanella
European Journal of Immunogenetics 2004
Host factors impacting the innate response in humans to the candidate adjuvants RC529 and monophosphoryl lipid A
L Tiberio, L Fletcher, JH Eldridge, DD Duncan
Vaccine 2004
Genetic polymorphisms predicting the outcome of bone marrow transplants
AM Dickinson, PG Middleton, V Rocha, E Gluckman, E Holler
British Journal of Haematology 2004
Cytokine gene polymorphisms and breast cancer susceptibility and prognosis*
KC Smith, AC Bateman, HM Fussell, WM Howell
European Journal of Immunogenetics 2004
Interleukin-10 production genotype protects against acute persistent rejection after lung transplantation
HX Zheng, GJ Burckart, K McCurry, S Webber, J Ristich, A Iacono, J Dauber, K McDade, W Grgurich, D Zaldonis, G Pillage, BP Griffith, A Zeevi
The Journal of Heart and Lung Transplantation 2004
Interleukin-10 and interleukin-6 gene polymorphisms as risk factors for Alzheimer’s disease
B Arosio, D Trabattoni, L Galimberti, P Bucciarelli, F Fasano, C Calabresi, CL Cazzullo, C Vergani, G Annoni, M Clerici
Neurobiology of Aging 2004
Interleukin 6 −174 G/C promoter gene polymorphism in centenarians: no evidence of association with human longevity or interaction with apolipoprotein E alleles
C Capurso, V Solfrizzi, A D'Introno, AM Colacicco, SA Capurso, C Semeraro, A Capurso, F Panza
Experimental Gerontology 2004
Th2/Th3 cytokine genotypes are associated with pregnancy loss
PA Costeas, A Koumouli, A Giantsiou-Kyriakou, A Papaloizou, L Koumas
Human Immunology 2004
Interleukin 6-174 G/C promoter gene polymorphism and sporadic Alzheimer's disease: geographic allele and genotype variations in Europe
C Capurso, V Solfrizzi, A D'Introno, AM Colacicco, SA Capurso, A Capurso, F Panza
Experimental Gerontology 2004
Heterozygote AG variant of −596 A/G IL-6 gene polymorphism is a marker for cutaneous T-cell lymphoma (CTCL)
JA Vasku, A Vasku, M Goldbergova, V Vasku
Clinical Immunology 2004
Analysis of common IL-6 promoter SNP variants and the AnTn tract in humans and primates and effects on plasma IL-6 levels following coronary artery bypass graft surgery
D Kelberman, M Fife, MV Rockman, DJ Brull, P Woo, SE Humphries
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2004
Interleukin-6 promoter polymorphism is associated with bone quality assessed by calcaneus ultrasound and previous fractures in a cohort of 75-year-old women
A Nordstr�m, P Gerdhem, H Br�ndstr�m, F Stiger, UH Lerner, M Lorentzon, K Obrant, P Nordstr�m, K �kesson
Osteoporosis International 2004
Periodontitis and Systemic Inflammation: Control of the Local Infection is Associated with a Reduction in Serum Inflammatory Markers
F DAiuto, M Parkar, G Andreou, J Suvan, PM Brett, D Ready, MS Tonetti
Journal of dental research 2004
Association of G-174C Polymorphism of the Interleukin-6 Gene Promoter with Graves' Ophthalmopathy
T Bednarczuk, A Kuryłowicz, Y Hiromatsu, J Kiljański, A Telichowska, J Nauman
Autoimmunity 2004
Polymorphisms of genes involved in innate immunity: association with preterm delivery
C Härtel, D Finas, P Ahrens, E Kattner, T Schaible, D Müller, H Segerer, K Albrecht, J Möller, K Diedrich, W Göpel
Molecular Human Reproduction 2004
Lack of IFN-gamma 2/2 homozygous genotype independently of recipient age and intensity of conditioning regimen influences the risk of aGVHD manifestation after HLA-matched sibling haematopoietic stem cell transplantation
A Mlynarczewska, B Wysoczanska, L Karabon, K Bogunia-Kubik, A Lange
Bone Marrow Transplantation 2004
A common polymorphism in the interleukin-6 gene promoter is associated with overweight
I Wernstedt, AL Eriksson, A Berndtsson, J Hoffstedt, S Skrtic, T Hedner, LM Hultén, O Wiklund, C Ohlsson, JO Jansson
International Journal of Obesity 2004
Independent association between inflammatory markers (C-reactive protein, interleukin-6 and TNF-α) and essential hypertension
LE Bautista, LM Vera, IA Arenas, G Gamarra
Journal of Human Hypertension 2004
Biological variations, genetic polymorphisms and familial resemblance of TNF-α and IL-6 concentrations: STANISLAS cohort
N Haddy, C Sass, S Maumus, B Marie, S Droesch, G Siest, D Lambert, S Visvikis
European Journal of Human Genetics 2004
The −174 G/C gene polymorphism in interleukin-6 is associated with an aggressive breast cancer phenotype
B Iacopetta, F Grieu, D Joseph
British Journal of Cancer 2004
Genetic susceptibility to tobacco-related cancer
X Wu, H Zhao, R Suk, DC Christiani
Oncogene 2004
Differential cytokine genotype frequencies among Canadian Aboriginal and Caucasian populations
L Larcombe, JD Rempel, I Dembinski, K Tinckam, C Rigatto, P Nickerson
Genes and Immunity 2004
Epistatic effects of genes encoding immunoglobulin GM allotypes and interleukin-6 on the production of autoantibodies to 60- and 65-kDa heat-shock proteins
JP Pandey, Z Prohászka, A Veres, G Füst, M Hurme
Genes and Immunity 2004
Influence of the interleukin-6 −174 G/C gene polymorphism on exercise training-induced changes in glucose tolerance indexes
JA McKenzie, EP Weiss, IA Ghiu, O Kulaputana, DA Phares, RE Ferrell, JM Hagberg
Journal of applied physiology 2004
The interleukin-6 gene: a susceptibility factor that may contribute to racial and ethnic disparities in breast cancer mortality
FG Berger
Breast Cancer Research and Treatment 2004
Racial disparities in female breast cancer in South Carolina: clinical evidence for a biological basis
JE Cunningham, WM Butler
Breast Cancer Research and Treatment 2004
Interindividual variation in the response by fibrinogen, C-reactive protein and interleukin-6 to yellow fever vaccination:
M Verschuur, MT van der Beek, HS Tak, LG Visser, MP de Maat
Blood Coagulation & Fibrinolysis 2004
Modest implication of interleukin-6 promoter polymorphisms in longevity
L Christiansen, L Bathum, K Andersen-Ranberg, B Jeune, K Christensen
Mechanisms of Ageing and Development 2004
Nutrition and Bone Health
MF Holick, B Dawson-Hughes
2004
Immunobiology of Organ Transplantation
DS Wilkes, WJ Burlingham
2004
Schizophrenie
HJ Möller, N Müller
2004
Novel twin study implicates IL-6 in the etiology of young adult Hodgkin lymphoma
JR Cerhan
Blood 2004
Body Mass Index and C-174G Interleukin-6 Promoter Polymorphism Interact in Predicting Type 2 Diabetes
M Möhlig, H Boeing, J Spranger, M Osterhoff, A Kroke, E Fisher, MM Bergmann, M Ristow, K Hoffmann, AF Pfeiffer
The Journal of clinical endocrinology and metabolism 2004
The Interleukin-6 G(−174)C Promoter Polymorphism Does Not Determine Plasma Interleukin-6 Concentrations in Experimental Endotoxemia in Humans
G Endler, C Marsik, C Joukhadar, R Marculescu, F Mayr, C Mannhalter, OF Wagner, B Jilma
Clinical chemistry 2004
HLA-DRB1 and -DQB1 alleles and gene polymorphisms of selected cytokines in systemic lupus erythematosus.
Hrycek A, Siekiera U, Cieślik P, Szkróbka W
Rheumatology International 2004
IL-6-174G/C genotype is associated with the bone mineral density response to oestrogen replacement therapy in post-menopausal women.
James L, Onambele G, Woledge R, Skelton D, Woods D, Eleftheriou K, Hawe E, Humphries SE, Haddad F, Montgomery H
European Journal of Applied Physiology 2004
IL-1 alpha (-889) promoter polymorphism is a risk factor for osteomyelitis
V Asensi, V Alvarez, E Valle, A Meana, J Fierer, E Coto, JA Carton, JA Maradona, J Paz, MA Dieguez, B la Fuente, A Moreno, S Rubio, MJ Tuya, J Sarasúa, S Llames, JM Arribas
American journal of medical genetics. Part A 2003
International Textbook of Diabetes Mellitus
RA DeFronzo, L Mandarino, E Ferrannini
International Textbook of Diabetes Mellitus 2003
Biologic therapies for juvenile arthritis
N Wilkinson, G Jackson, J Gardner-Medwin
Archives of disease in childhood 2003
Interleukin-6 promoter haplotypes and interleukin-6 cytokine responses
FA Rivera-Chavez, DL Peters-Hybki, RC Barber, GE O'Keefe
Shock (Augusta, Ga.) 2003
Association of IL-10 polymorphism with severity of illness in community acquired pneumonia
PM Gallagher, G Lowe, T Fitzgerald, A Bella, CM Greene, NG McElvaney, SJ O'Neill
Thorax 2003
Cytokine gene polymorphisms associated with symptomatic parvovirus B19 infection
JR Kerr, M McCoy, B Burke, DL Mattey, V Pravica, IV Hutchinson
Journal of clinical pathology 2003
Interleukin-6 (IL6) Genotype Is Associated With Fat-Free Mass in Men But Not Women
SM Roth, MA Schrager, MR Lee, EJ Metter, BF Hurley, RE Ferrell
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2003
Genetic variability and transplantation
B Marder, B Schröppel, B Murphy
Current Opinion in Urology 2003
The therapeutic potential of interleukin-6 in treating obesity
K Wallenius, JO Jansson, V Wallenius
Expert Opinion on Biological Therapy 2003
Cytokine response to endotoxin in individuals heterozygous for the Δ32 mutation of chemokine receptor CCR5
M Heesen, EF Schippers, B Bloemeke, D Kunz, JT van Dissel
Cytokine 2003
C-reactive protein and interleukin-6 in vascular disease
M Rattazzi, M Puato, E Faggin, B Bertipaglia, A Zambon, P Pauletto
Journal of Hypertension 2003
Cytokine gene polymorphisms moderate illness severity in infants with respiratory syncytial virus infection
DA Gentile, WJ Doyle, A Zeevi, J Howe-Adams, S Kapadia, J Trecki, DP Skoner
Human Immunology 2003
Genetic variation and hematopoietic stem cell transplantation: expansion of the paradigm
SA Savage, S Chanock
Pediatric Transplantation 2003
Cytokine levels during symptomatic viral upper respiratory tract infection
DA Gentile, E Villalobos, B Angelini, D Skoner
Annals of Allergy Asthma & Immunology 2003
Combined analysis of cytokine genotype polymorphism and the level of expression with allograft function in African–American renal transplant patients
DO McDaniel, WH Barber, C Nguyan, SW Rhodes, WL May, LS McDaniel, PJ Vig, LL Jemeson, DE Butkus
Transplant Immunology 2003
The (−174) G/C polymorphism in the interleukin-6 gene is associated with the severity of acute cerebrovascular events
S Greisenegger, G Endler, D Haering, M Schillinger, W Lang, W Lalouschek, C Mannhalter
Thrombosis Research 2003
Current concepts of the inflammatory response after major trauma: an update
PV Giannoudis
Injury 2003
Absence of linkage between the interleukin-6 gene (−174 G/C) polymorphism and migraine
I Rainero
Neuroscience Letters 2003
The interleukin-6 promoter polymorphism in Gaucher disease: a new modifier gene?
G Altarescu, M Phillips, AJ Foldes, D Elstein, A Zimran, M Mates
QJM 2003
The role of the interleukin-6 family of cytokines in inflammatory arthritis and bone turnover
PK Wong, IK Campbell, PJ Egan, M Ernst, IP Wicks
Arthritis & Rheumatism 2003
Impact of pathogen burden in patients with coronary artery disease in relation to systemic inflammation and variation in genes encoding cytokines
JL Georges, HJ Rupprecht, S Blankenberg, O Poirier, C Bickel, G Hafner, V Nicaud, J Meyer, F Cambien, L Tiret
The American Journal of Cardiology 2003
Cytokine gene polymorphisms in atopic dermatitis
K Reich, G Westphal, IR König, R Mössner, P Schupp, C Gutgesell, E Hallier, A Ziegler, C Neumann
British Journal of Dermatology 2003
Cytokine gene polymorphisms moderate responses to respiratory syncytial virus in adults
DA Gentile, WJ Doyle, A Zeevi, O Piltcher, DP Skoner
Human Immunology 2003
Genetic control of postoperative systemic inflammatory reaction and pulmonary and renal complications after coronary artery surgery
M Gaudino, AD Castelnuovo, R Zamparelli, F Andreotti, F Burzotta, L Iacoviello, F Glieca, F Alessandrini, G Nasso, MB Donati, A Maseri, R Schiavello, G Possati
The Journal of Thoracic and Cardiovascular Surgery 2003
Correlation between transcranial interleukin-6 gradient and outcome in patients with acute brain injury:
E Miñambres, A Cemborain, P Sánchez-Velasco, M Gandarillas, G Díaz-Regañón, U Sánchez-González, F Leyva-Cobián
Critical Care Medicine 2003
Lower prevalence of IL-4 receptor α-chain gene 1902G variant in very-low-birth-weight infants with necrotizing enterocolitis
A Treszl, E Héninger, A Kálmán, A Schuler, T Tulassay, B Vásárhelyi
Journal of Pediatric Surgery 2003
Interleukin-6–174 G/C Promoter Gene Polymorphism C Allele Reduces Alzheimer's Disease Risk
F Faltraco, K Bürger, P Zill, SJ Teipel, HJ Möller, H Hampel, B Bondy, M Ackenheil
Journal of the American Geriatrics Society 2003
Age-Specific Analysis of Normal Cytokine Levels in Healthy Infants
PA Berdat, TJ Wehrle, A Küng, F Achermann, M Sutter, TP Carrel, UE Nydegger
Clinical chemistry and laboratory medicine : CCLM / FESCC 2003
Association of interleukin-6 -174G/C promoter polymorphism with hypertension and left ventricular hypertrophy in dialysis patients
A Losito, K Kalidas, S Santoni, S Jeffery
Kidney International 2003
Interleukin-6 gene alleles affect the risk of Alzheimer’s disease and levels of the cytokine in blood and brain
F Licastro, LM Grimaldi, M Bonafè, C Martina, F Olivieri, L Cavallone, S Giovanietti, E Masliah, C Franceschi
Neurobiology of Aging 2003
Polymorphisms of IL-1B, IL-1RN, IL-2, IL-4, IL-6, IL-10, and IFN-γ genes in the Korean population
CW Pyo, SS Hur, YK Kim, HB Choi, YS Hong, DW Kim, CC Kim, HK Kim, TG Kim
Human Immunology 2003
Epidemiology of the rheumatic diseases of childhood
PJ Manners
Current Rheumatology Reports 2003
Polymorphism at position -174 of IL-6 gene is associated with susceptibility to chronic periodontitis in a Caucasian Brazilian population
PC Trevilatto, RM Scarel-Caminaga, RB de Brito, AP de Souza, SR Line
Journal of Clinical Periodontology 2003
Idiopathic Thrombocytopenic Purpura in Adults:
D Provan, A Newland
Journal of Pediatric Hematology/Oncology 2003
The role of cytokine gene polymorphisms in the pathogenesis of abdominal aortic aneurysms: A case-control study
MJ Bown, PR Burton, T Horsburgh, ML Nicholson, PR Bell, RD Sayers
Journal of Vascular Surgery 2003
Racial differences in selected cytokine allelic and genotypic frequencies among healthy, pregnant women in North Carolina
MI Hassan, Y Aschner, CH Manning, J Xu, JL Aschner
Cytokine 2003
The molecular genetics of cardiovascular disease: clinical implications
JW Stephens, SE Humphries
Journal of Internal Medicine 2003
Association between -174 G/C polymorphism of interleukin-6 gene and alcoholism
O Sery, R Hladilova, M Novotny, H Hribkova, V Znojil, P Zvolsky
Acta Neuropsychiatrica 2003
Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma
WM Howell, SJ Turner, JM Theaker, AC Bateman
European Journal of Immunogenetics 2003
Elucidating the Unexplained Underperformance Syndrome in Endurance Athletes: The Interleukin-6 Hypothesis
PJ Robson
Sports Medicine 2003
Cytokine gene polymorphisms in allergiccontact dermatitis
GA Westphal, A Schnuch, R Moessner, IR Konig, B Kranke, E Hallier, A Ziegler, K Reich
Contact Dermatitis 2003
Interleukin-6 Genetic Polymorphisms are not Related to Helicobacter pylori-Associated Gastroduodenal Diseases
IR Hwang, PI Hsu, LE Peterson, O Gutierrez, JG Kim, DY Graham, Y Yamaoka
Helicobacter 2003
Interleukin-6 promoter −174 polymorphism and spontaneous preterm birth
HN Simhan, MA Krohn, JM Roberts, A Zeevi, SN Caritis
American Journal of Obstetrics and Gynecology 2003
The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity
Agata Kubaszek, Jussi Pihlajamäki, Kari Punnonen, Pauli Karhapää, Ilkka Vauhkonen, Markku Laakso
Diabetes 2003
Platelet Counts and Interleukin-6 (IL-6) Promoter Polymorphism in Patients with Gaucher Disease
D Elstein, G Altarescu, A Zimran
Hematology 2003
Analysis of an Interleukin-6 Gene Promoter Polymorphism in Women With Endometriosis Polymorphism in Women With Endometriosis By Pyrosequencing
F Wieser, G Fabjani, C Tempfer, C Schneeberger, M Sator, J Huber, R Wenzl
Journal of the Society for Gynecologic Investigation 2003
Genetic Polymorphisms in Sepsis and Septic Shock
CL Holmes, JA Russell, KR Walley
Chest 2003
Polymorphisms in the 5′-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression
J Duan, AR Sanders, JE Molen, L Martinolich, BJ Mowry, DF Levinson, RR Crowe, JM Silverman, PV Gejman
Molecular Psychiatry 2003
Genomic polymorphic profiles in an Irish population with meningococcaemia: is it possible to predict severity and outcome of disease?
J Balding, CM Healy, WJ Livingstone, B White, L Mynett-Johnson, M Cafferkey, OP Smith
Genes and Immunity 2003
Genetic polymorphisms in Spanish rheumatoid arthritis patients: an association and linkage study
A Martinez, M Pascual, D Pascual-Salcedo, A Balsa, J Martin, EG de la Concha
Genes and Immunity 2003
Genomic analysis of Th1–Th2 cytokine genes in an AIDS cohort: identification of IL4 and IL10 haplotypes associated with the disease progression
A Vasilescu, SC Heath, R Ivanova, H Hendel, H Do, A Mazoyer, E Khadivpour, FX Goutalier, K Khalili, J Rappaport, GM Lathrop, F Matsuda, JF Zagury
Genes and Immunity 2003
Functional and prognostic relevance of the ?173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis
FD Benedetti, C Meazza, M Vivarelli, F Rossi, A Pistorio, R Lamb, M Lunt, W Thomson, A Ravelli, R Donn, A Martini
Arthritis & Rheumatism 2003
Cytokine gene polymorphisms in patients infected with hepatitis B virus
Z Ben-Ari, E Mor, O Papo, B Kfir, J Sulkes, AR Tambur, R Tur-Kaspa, T Klein
The American Journal of Gastroenterology 2003
Recent advances in the management of juvenile idiopathic arthritis
P Woo
Current Paediatrics 2003
In vitro IL-6 production by EBV-immortalized B lymphocytes from young and elderly people genotyped for −174 C/G polymorphism in IL-6 gene: a model to study the genetic basis of inflamm-aging
F Olivieri, M Bonafè, S Giovagnetti, R Stecconi, M Cardelli, L Cavallone, L Spazzafumo, F Marchegiani, G Carrieri, E Mugianesi, C Giampieri, M Centurelli, R Moresi, S Tesei, R Lisa, C Viticchi, L Falsetti, S Salvioli, C Franceschi
Mechanisms of Ageing and Development 2003
Polymorphisms in tumour necrosis factor-?, transforming growth factor-?, interleukin-10, interleukin-6, interferon-?, and outcome of hepatitis C virus infection
S Barrett, M Collins, C Kenny, E Ryan, CO Keane, J Crowe
Journal of Medical Virology 2003
Interleukin-6 Promoter Haplotypes and Interleukin-6 Cytokine Responses:
FA Rivera-Chavez, DL Peters-Hybki, RC Barber, GE O'Keefe
Shock 2003
Interleukin-6-gene C/G 174 polymorphism in nonagenarian and octogenarian subjects in the BELFAST study. Reciprocal effects on IL-6, soluble IL-6 receptor and for IL-10 in serum and monocyte supernatants
IM Rea, OA Ross, M Armstrong, S McNerlan, DH Alexander, MD Curran, D Middleton
Mechanisms of Ageing and Development 2003
The ?174G allele of the interleukin-6 gene confers susceptibility to systemic arthritis in children: A multicenter study using simplex and multiplex juvenile idiopathic arthritis families
EM Ogilvie, MS Fife, SD Thompson, N Twine, M Tsoras, M Moroldo, SA Fisher, CM Lewis, AM Prieur, DN Glass, P Woo
Arthritis & Rheumatism 2003
Cytokines and Chemokines in Autoimmune Disease
P Santamaria
2003
Inflammation and Cardiac Diseases
GZ Feuerstein, P Libby, DL Mann
2003
New Developments in Allotransplant Immunology
AJ Barrett, K Rezvani, S Solomon, AM Dickinson, XN Wang, G Stark, H Cullup, M Jarvis, PG Middleton, N Chao
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2003
Association of interleukin-6 promoter variant with bone mineral density in pre-menopausal women
HW Chung, JS Seo, SE Hur, HL Kim, JY Kim, JH Jung, LH Kim, BL Park, HD Shin
Journal of Human Genetics 2003
The −174G/C Interleukin-6 Polymorphism Influences Postoperative Interleukin-6 Levels and Postoperative Atrial Fibrillation. Is Atrial Fibrillation an Inflammatory Complication?
M Gaudino, F Andreotti, R Zamparelli, AD Castelnuovo, G Nasso, F Burzotta, L Iacoviello, MB Donati, R Schiavello, A Maseri, G Possati
Circulation 2003
The interleukin-6 (−174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians
B Vozarova, JM Fernández-Real, WC Knowler, L Gallart, RL Hanson, JD Gruber, W Ricart, J Vendrell, C Richart, PA Tataranni, JK Wolford
Human Genetics 2003
The role of cytokines in prostatitis
TL Jang, AJ Schaeffer
World Journal of Urology 2003
The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians.
Vozarova B, Fernández-Real JM, Knowler WC, Gallart L, Hanson RL, Gruber JD, Ricart W, Vendrell J, Richart C, Tataranni PA, Wolford JK
Human Genetics 2003
Association of interleukin-6 promoter variant with bone mineral density in pre-menopausal women.
Chung HW, Seo JS, Hur SE, Kim HL, Kim JY, Jung JH, Kim LH, Park BL, Shin HD
Journal of Human Genetics 2003
Elucidating the unexplained underperformance syndrome in endurance athletes : the interleukin-6 hypothesis.
Robson P
Sports medicine (Auckland, N.Z.) 2003
Epidemiology of the rheumatic diseases of childhood.
Manners PJ
Current Rheumatology Reports 2003
Association of cytokine single nucleotide polymorphisms with B7 costimulatory molecules in kidney allograft recipients
A Hutchings, L Guay-Woodford, JM Thomas, CJ Young, WM Purcell, V Pravica, C Perrey, IV Hutchinson, MR Benfield
Pediatric Transplantation 2002
The −597 G→A and −174 G→C Polymorphisms in the Promoter of the IL-6 Gene Are Associated with Hyperandrogenism
G Villuendas, JL san Millán, J Sancho, HF Escobar-Morreale
The Journal of clinical endocrinology and metabolism 2002
Cytokines and juvenile idiopathic arthritis
P Woo
Current Rheumatology Reports 2002
The effect of the Interleukin-6-174G > C promoter gene polymorphism on endothelial function in healthy volunteers
DJ Brull, CP Lesson, HE Montgomery, M Mullen, M deDivitiis, SE Humphries, JE Deanfield
European Journal of Clinical Investigation 2002
GENETIC AND ENVIRONMENTAL INFLUENCES ON IL-6 AND TNF-α PLASMA LEVELS IN APPARENTLY HEALTHY GENERAL POPULATION
I Pantsulaia, S Trofimov, E Kobyliansky, G Livshits
Cytokine 2002
Carotid intima-media thickness is associated with allelic variants of stromelysin-1, interleukin-6, and hepatic lipase genes: the Northern Manhattan Prospective Cohort Study
T Rundek, MS Elkind, J Pittman, B Boden-Albala, S Martin, SE Humphries, SH Juo, RL Sacco
Stroke; a journal of cerebral circulation 2002
Template-directed dye-terminator incorporation with fluorescence polarization detection for analysis of single nucleotide polymorphisms implicated in sepsis
BD Freeman, TG Buchman, S McGrath, AR Tabrizi, BA Zehnbauer
The Journal of molecular diagnostics : JMD 2002
Juvenile idiopathic arthritis genetics - what's new? What's next?
W Thomson, R Donn
Arthritis research 2002
Association between a functional interleukin-6 gene polymorphism and peak bone mineral density and postmenopausal bone loss in women: the ofely study
P Garnero, O Borel, E Sornay-Rendu, F Duboeuf, R Jeffery, P Woo, PD Delmas
Bone 2002
Polymorphisms in Immunoregulatory Genes
AK Daly, CP Day, PT Donaldson
American Journal of PharmacoGenomics 2002
The role of the immune system in the insulin resistance syndrome
MR Lewis, RP Tracy
Current Diabetes Reports 2002
Can the interleukin-6 response to endotoxin be predicted? Studies of the influence of a promoter polymorphism of the interleukin-6 gene, gender, the density of the endotoxin receptor CD14, and inflammatory cytokines
M Heesen, B Bloemeke, N Heussen, D Kunz
Critical Care Medicine 2002
The interleukin-6 −174promoter polymorphism is associated with long-term kidney allograft survival
M Müller-Steinhardt, C Härtel, B Müller, H Kirchner, L Fricke
Kidney International 2002
The −174 C/G locus affects in vitro/in vivo IL-6 production during aging
F Olivieri, M Bonafè, L Cavallone, S Giovagnetti, F Marchegiani, M Cardelli, E Mugianesi, C Giampieri, R Moresi, R Stecconi, R Lisa, C Franceschi
Experimental Gerontology 2002
Levels of IL-6 and soluble IL-6 receptor are increased in HIV patients with a history of immune restoration disease after HAART
SF Stone, P Price, NM Keane, RJ Murray, MA French
HIV Medicine 2002
Myeloma aetiology and epidemiology
GJ Morgan, FE Davies, M Linet
Biomedicine & Pharmacotherapy 2002
A -174G/C polymorphism of the interleukin-6 gene in patients with lacunar infarction
M Revilla
Neuroscience Letters 2002
Advances in Cell Aging and Gerontology
T Fülöp, K Hirokawa, G Dupuis, A Larbi, G Pawelec
Advances in Cell Aging and Gerontology 2002
IL-6 in autoimmune disease and chronic inflammatory proliferative disease
K Ishihara, T Hirano
Cytokine & Growth Factor Reviews 2002
Omega-3 Fatty Acids in Inflammation and Autoimmune Diseases
AP Simopoulos
Journal of the American College of Nutrition 2002
Bone mineral mass is associated with interleukin 1 receptor autoantigen and TNF-α gene polymorphisms in post-menopausal Mediterranean women
R Fontova, C Gutiérrez, J Vendrell, M Broch, I Vendrell, I Simón, JM Fernández-Real, C Richart
Journal of Endocrinological Investigation 2002
The −174 G/C Polymorphism of the Interleukin-6 Gene Promoter is Associated with Peripheral Artery Occlusive Disease
A Flex, E Gaetani, R Pola, A Santoliquido, F Aloi, P Papaleo, AD Lago, E Pola, M Serricchio, P Tondi, P Pola
European Journal of Vascular and Endovascular Surgery 2002
Interleukin-6 polymorphism (-634C/G) in the promotor region and the progression of diabetic nephropathy in Type 2 diabetes
A Kitamura, G Hasegawa, H Obayashi, K Kamiuchi, M Ishii, M Yano, T Tanaka, M Yamaguchi, H Shigeta, M Ogata, N Nakamura, T Yoshikawa
Diabetic Medicine 2002
Frequency of cytokine polymorphisms in populations from western Europe, Africa, Asia, the Middle East and South America
A Meenagh, F Williams, OA Ross, C Patterson, C Gorodezky, M Hammond, WA Leheny, D Middleton
Human Immunology 2002
Cytokine Polymorphisms in Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Association with Diagnosis and Treatment Response
DA Shoskes, Q Albakri, K Thomas, D Cook
The Journal of Urology 2002
Polymorphism of the cytokine genes and IgA nephropathy
J Syrjanen, M Hurme, T Lehtimaki, J Mustonen, A Pasternack
Kidney International 2002
The –74 G/C polymorphism of the interleukin-6 gene promoter is associated with Alzheimerʼs disease in an Italian population:
R Pola, A Flex, E Gaetani, AD Lago, L Gerardino, P Pola, R Bernabei
NeuroReport 2002
THE −174 G TO C POLYMORPHISM OF INTERLEUKIN-6 GENE IS VERY RARE IN KOREANS
CS Lim, S Zheng, YS Kim, C Ahn, JS Han, S Kim, JS Lee, DW Chae
Cytokine 2002
Polymorphisms in cytokine genes define subpopulations of HIV-1 patients who experienced immune restoration diseases:
P Price, G Morahan, D Huang, E Stone, KY Cheong, A Castley, M Rodgers, MQ McIntyre, LJ Abraham, MA French
AIDS 2002
Ethnicity Greatly Influences Cytokine Gene Polymorphism Distribution
SC Hoffmann, EM Stanley, ED Cox, BS DiMercurio, DE Koziol, DM Harlan, AD Kirk, PJ Blair
American Journal of Transplantation 2002
Effect of the interleukin-6 promoter polymorphism (−174 G/C) on the incidence and outcome of sepsis:
B Schlüter, C Raufhake, M Erren, H Schotte, F Kipp, S Rust, HV Aken, G Assmann, E Berendes
Critical Care Medicine 2002
Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease
G Endler, A Klimesch, H Sunder-Plassmann, M Schillinger, M Exner, C Mannhalter, N Jordanova, G Christ, R Thalhammer, K Huber, R Sunder-Plassmann
British Journal of Haematology 2002
Thalidomide therapy for recalcitrant systemic onset juvenile rheumatoid arthritis
TJ Lehman, KH Striegel, KB Onel
The Journal of Pediatrics 2002
−174 G/C interleukin-6 gene polymorphism and increased risk of multi-infarct dementia: a case-control study
R Pola, E Gaetani, A Flex, F Aloi, P Papaleo, L Gerardino, DD Martini, R Flore, P Pola, R Bernabei
Experimental Gerontology 2002
Interleukin-10, interleukin-6 and interferon-γ gene polymorphisms in melanoma patients:
JA Martínez-Escribano, MR Moya-Quiles, M Muro, O Montes-Ares, T Hernández-Caselles, JF Frías, MR Álvarez-López
Melanoma Research 2002
Symposium on ’Nutrition in the post-genomic era’ Plenary session 4: Genetic variation and diet-related disease
WM Howell, PC Calder, RF Grimble
Proceedings of the Nutrition Society 2002
The immunological synapse
RJ Creusot, NA Mitchison, NM Terazzini
Molecular Immunology 2002
Allele frequencies of polymorphisms of TNFA, IL-6, IL-10 and IFNG in an Italian Caucasian population
F Poli, A Nocco, S Berra, M Scalamogna, E Taioli, E Longhi, G Sirchia
European Journal of Immunogenetics 2002
The role of transsignalling via the agonistic soluble IL-6 receptor in human diseases
Karl-Josef Kallen
Biochimica et Biophysica Acta 2002
Tumor necrosis factor receptor type II (exon 6) and interleukin-6 (−174) gene polymorphisms are not associated with family history but tumor necrosis factor receptor type II is associated with hypertension in patients with rheumatoid arthritis from northe: Concise Communications
SR Dahlqvist, L Ärlestig, C Sikström, S Linghult
Arthritis & Rheumatism 2002
The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists
DC Shields, AP Fitzgerald, PA O'Neill, C Muckian, D Kenny, B Moran, CP Cannon, CE Byrne, DJ Fitzgerald
The Pharmacogenomics Journal 2002
The −174 G/C polymorphism of the interleukin-6 gene promoter and essential hypertension in an elderly Italian population
R Pola, A Flex, E Gaetani, P Pola, R Bernabei
Journal of Human Hypertension 2002
A detailed genetic map of the chromosome 7 bronchial hyper-responsiveness locus
NI Leaves, S Bhattacharyya, S Wiltshire, WO Cookson
European Journal of Human Genetics 2002
IL-1B and IL-6 gene polymorphisms encode significant risk for the development of recurrent aphthous stomatitis (RAS)
MR Bazrafshani, AH Hajeer, WE Ollier, MH Thornhill
Genes and Immunity 2002
Safe disposal of inflammatory monosodium urate monohydrate crystals by differentiated macrophages
RC Landis, DR Yagnik, O Florey, P Philippidis, V Emons, JC Mason, DO Haskard
Arthritis & Rheumatism 2002
Cerebrospinal fluid levels of ??-amyloid(42) in patients with Alzheimer??s disease are related to the exon 2 polymorphism of the cathepsin D gene:
A Papassotiropoulos, HD Lewis, M Bagli, F Jessen, U Ptok, A Schulte, MS Shearman, R Heun
NeuroReport 2002
Common Promoter Variant in Cyclooxygenase-2 Represses Gene Expression: Evidence of Role in Acute-Phase Inflammatory Response
A Papafili, MR Hill, DJ Brull, RJ McAnulty, RP Marshall, SE Humphries, GJ Laurent
Arteriosclerosis, thrombosis, and vascular biology 2002
Interleukin-6 −174G>C Polymorphism and Risk of Coronary Heart Disease in West of Scotland Coronary Prevention Study (WOSCOPS)
F Basso, GD Lowe, A Rumley, AD McMahon, SE Humphries
Arteriosclerosis, thrombosis, and vascular biology 2002
In the Elderly, Interleukin-6 Plasma Levels and the −174G>C Polymorphism Are Associated With the Development of Cardiovascular Disease
NS Jenny, RP Tracy, MS Ogg, LA Luong, LH Kuller, AM Arnold, AR Sharrett, SE Humphries
Arteriosclerosis, thrombosis, and vascular biology 2002
Genetic Polymorphisms Influencing Therapy and Susceptibility to Rejection in Organ Allograft Recipients:
F Poli, G Piccolo, M Scalamogna
BioDrugs 2002
Host defense and inflammatory gene polymorphisms are associated with outcomes after HLA-identical sibling bone marrow transplantation
V Rocha, RF Franco, R Porcher, H Bittencourt, WA Silva, A Latouche, A Devergie, H Espérou, P Ribaud, G Socié, MA Zago, E Gluckman
Blood 2002
Human gene mutation in pathology and evolution
DN Cooper
Journal of Inherited Metabolic Disease 2002
Simultaneous genotyping of single nucleotide polymorphisms in the IL-6, IL-10, TNFα and TNFβ genes: Tseng et al : Multiplex-PCR-RFLP
LH Tseng, PJ Chen, MT Lin, K Singleton, EG Martin, AH Yen, SM Chuang, PJ Martin, JA Hansen
Tissue Antigens 2002
Genetic Influences on Rheumatoid Arthritis in African Americans
LB Hughes, LW Moreland, SL Bridges
Immunologic Research 2002
The role of the immune system in the insulin resistance syndrome.
Lewis MR, Tracy RP
Current Diabetes Reports 2002
Bone mineral mass is associated with interleukin 1 receptor autoantigen and TNF-alpha gene polymorphisms in post-menopausal Mediterranean women.
Fontova R, Gutiérrez C, Vendrell J, Broch M, Vendrell I, Simón I, Fernández-Real JM, Richart C
Journal of Endocrinological Investigation 2002
Cortical bone resorption during exercise is interleukin-6 genotype-dependent.
Dhamrait SS, James L, Brull DJ, Myerson S, Hawe E, Pennell DJ, World M, Humphries SE, Haddad F, Montgomery HE
European Journal of Applied Physiology 2002
A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity
TD LeVan, JW Bloom, TJ Bailey, CL Karp, M Halonen, FD Martinez, D Vercelli
Journal of immunology (Baltimore, Md. : 1950) 2001
Predisposing factors in the Spondyloarthropathies: New insights into the role of HLA-B27
RA Colbert, S Prahalad
Current Rheumatology Reports 2001
Preterm labour and delivery: a genetic predisposition
DS Dizon-Townson
Paediatric and Perinatal Epidemiology 2001
Interleukin-1 receptor antagonist as therapy for inflammatory disorders
BD Freeman, TG Buchman
Expert Opinion on Biological Therapy 2001
Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study
JS Pankow, AR Folsom, M Cushman, IB Borecki, PN Hopkins, JH Eckfeldt, RP Tracy
Atherosclerosis 2001
Platelet count and interleukin 6 gene polymorphism in healthy subjects
JM Fernandez-Real, J Vendrell, C Richart, C Gutierrez, W Ricart
BMC Medical Genetics 2001
Inter-individual differences in cytokine release in patients undergoing cardiac surgery with cardiopulmonary bypass
A Roth-Isigkeit, L Hasselbach, E Ocklitz, S Brückner, A Ros, H Gehring, P Schmucker, L Rink, M Seyfarth
Clinical & Experimental Immunology 2001
Molecular epidemiology of preterm delivery: methodology and challenges
X Wang, B Zuckerman, G Kaufman, P Wise, M Hill, T Niu, L Ryan, D Wu, X Xu
Paediatric and Perinatal Epidemiology 2001
Increased cytokine release by leucocytes in survivors of stroke at young age
AJ Grau, M Aulmann, C Lichy, H Meiser, F Buggle, T Brandt, C Grond-Ginsbach
European Journal of Clinical Investigation 2001
Cytokine gene polymorphisms and susceptibility to juvenile idiopathic arthritis
RP Donn, JH Barrett, A Farhan, A Stopford, L Pepper, E Shelley, N Davies, WE Ollier, W Thomson
Arthritis & Rheumatism 2001
A gender-dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity
M Bonafè, F Olivieri, L Cavallone, S Giovagnetti, F Marchegiani, M Cardelli, C Pieri, M Marra, R Antonicelli, R Lisa, MR Rizzo, G Paolisso, D Monti, C Franceschi
European Journal of Immunology 2001
GvHD risk assessment in hematopoietic stem cell transplantation: role of cytokine gene polymorphisms and an in vitro human skin explant model
AM Dickinson, J Cavet, H Cullup, XN Wang, L Sviland, PG Middleton
Human Immunology 2001
Candidate Genes for Osteoporosis
T Niu, X Xu
American Journal of PharmacoGenomics 2001
A study of cytokine gene polymorphisms and protein secretion in renal transplantation
NH Cartwright, LJ Keen, AG Demaine, NJ Hurlock, RJ McGonigle, PA Rowe, JF Shaw, RM Szydlo, ER Kaminski
Transplant Immunology 2001
Determination of cytokine regulatory haplotypes by induced heteroduplex analysis of DNA
NA Wood, LJ Keen, LA Tilley, JL Bidwell
Journal of Immunological Methods 2001
The −174/−597 promoter polymorphisms in the interleukin-6 gene are not associated with susceptibility to multiple sclerosis
M Fedetz, F Matesanz, M Pascual, J Martı́n, O Fernández, M Guerrero, A Alcina
Journal of the Neurological Sciences 2001
Role of infection and cytokines in the pathogenesis of chronic obstructive pulmonary disease :
MW Raza, AJ Bint, CC Blackwell
Reviews in Medical Microbiology 2001
Relation of the −174 G/C polymorphism of interleukin-6 to interleukin-6 plasma levels and to length of hospitalization after surgical coronary revascularization
F Burzotta, L Iacoviello, AD Castelnuovo, F Glieca, N Luciani, R Zamparelli, R Schiavello, MB Donati, A Maseri, GF Possati, F Andreotti
The American Journal of Cardiology 2001
Atherosclerosis and Autoimmunity
EC Lau
Atherosclerosis and Autoimmunity 2001
Interleukin-6 (IL-6) and the Prognosis of Abdominal Aortic Aneurysms
KG Jones, DJ Brull, LC Brown, M Sian, RM Greenhalgh, SE Humphries, JT Powell
Circulation 2001
An Analysis of Acute Changes in Interleukin-6 Levels After Treatment of Hepatitis C with Consensus Interferon
SJ Cotler, KR Reddy, J McCone, DL Wolfe, A Liu, TR Craft, MW Ferris, AJ Conrad, J Albrecht, M Morrissey, DR Ganger, H Rosenblate, LM Blatt, DM Jensen, MW Taylor
Journal of Interferon & Cytokine Research 2001
The polymorphism at position ???174 of the IL-6 gene is not associated with inflammatory bowel disease:
W Klein, A Tromm, T Griga, H Fricke, C Folwaczny, M Hocke, K Eitner, M Marx, JT Epplen
European Journal of Gastroenterology & Hepatology 2001
Importance of underlying mechanism and genotype on outcome of sepsis trials:
L McIntyre, KR Walley
Critical Care Medicine 2001
Immunogenetics and genomics
AV Hill
The Lancet 2001
The effect of cytokine gene polymorphisms on pediatric heart allograft outcome
MR Awad, S Webber, G Boyle, C Sturchioĉ, M Ahmed, J Martell, Y Law, SA Miller, P Bowman, S Gribar, F Pigula, G Mazariegos, BP Griffith, A Zeevi
The Journal of Heart and Lung Transplantation 2001
A novel 5?-flanking region polymorphism of macrophage migration inhibitory factor is associated with systemic-onset juvenile idiopathic arthritis
RP Donn, E Shelley, WE Ollier, W Thomson
Arthritis & Rheumatism 2001
Interleukin 6 and Haemostasis
R Kerr, D Stirling, CA Ludlam
British Journal of Haematology 2001
The G to C polymorphism at -174 of the interleukin-6 gene is rare in a Southern Chinese population:
R Zhai, G Liu, C Yang, C Huang, C Wu, DC Christiani
Pharmacogenetics 2001
Interleukin 6, tumour necrosis factor alpha and lymphotoxin alpha polymorphisms in monoclonal gammopathy of uncertain significance and multiple myeloma
AM Dring, FE Davies, SJ Rollinson, PL Roddam, AC Rawstron, JA Child, AS Jack, GJ Morgan
British Journal of Haematology 2001
INVESTIGATION OF NOVEL POLYMORPHISMS WITHIN THE 3′ REGION OF THE IL-6 GENE IN PATIENTS WITH RHEUMATOID ARTHRITIS USING GENESCAN ANALYSIS
A Crilly, JM Bartlett, A White, D Stirling, H Capell, R Madhok
Cytokine 2001
Lack of association between human longevity and polymorphisms of IL-1 cluster, IL-6, IL-10 and TNF-α genes in Finnish nonagenarians
XY Wang, M Hurme, M Jylhä, A Hervonen
Mechanisms of Ageing and Development 2001
ASSOCIATION OF CYTOKINE POLYMORPHIC INHERITANCE AND IN VITRO CYTOKINE PRODUCTION IN ANTI-CD3/CD28-STIMULATED PERIPHERAL BLOOD LYMPHOCYTES1:
SC Hoffmann, EM Stanley, ED Cox, N Craighead, BS DiMercurio, DE Koziol, DM Harlan, AD Kirk, PJ Blair
Transplantation 2001
TNF-??, IL-6, IFN-??, AND IL-10 GENE EXPRESSION POLYMORPHISMS AND THE IL-4 RECEPTOR ??-CHAIN VARIANT Q576R: EFFECTS ON RENAL ALLOGRAFT OUTCOME:
AB Hahn, JC Kasten-Jolly, DM Constantino, E Graffunder, TP Singh, GK Shen, DJ Conti
Transplantation 2001
BOTH GENETIC AND CLINICAL FACTORS PREDICT THE DEVELOPMENT OF GRAFT-VERSUS-HOST DISEASE AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION:
G Soci, P Loiseau, R Tamouza, A Janin, M Busson, E Gluckman, D Charron
Transplantation 2001
ROLE OF CYTOKINE GENE POLYMORPHISM IN HEPATITIS C RECURRENCE AND ALLOGRAFT REJECTION AMONG LIVER TRANSPLANT RECIPIENTS 1:
AR Tambur, JW Ortegel, Z Ben-Ari, E Shabtai, T Klein, R Michowiz, R Tur-Kaspa, E Mor
Transplantation 2001
CYTOKINE POLYMORPHIC ANALYSES INDICATE ETHNIC DIFFERENCES IN THE ALLELIC DISTRIBUTION OF INTERLEUKIN-2 AND INTERLEUKIN-61:
ED Cox, SC Hoffmann, BS DiMercurio, RA Wesley, DM Harlan, AD Kirk, PJ Blair
Transplantation 2001
On Genetics, Inflammation, and Abdominal Aortic Aneurysm: Can Single Nucleotide Polymorphisms Predict the Outcome?
AJ Marian
Circulation 2001
Interleukin-6 Gene −174G>C and −572G>C Promoter Polymorphisms Are Strong Predictors of Plasma Interleukin-6 Levels After Coronary Artery Bypass Surgery
DJ Brull, HE Montgomery, J Sanders, S Dhamrait, L Luong, A Rumley, GD Lowe, SE Humphries
Arteriosclerosis, thrombosis, and vascular biology 2001
NFκB Polymorphisms and susceptibility to type 1 diabetes
DM Hegazy, DA OReilly, BM Yang, AD Hodgkinson, BA Millward, AG Demaine
Genes and Immunity 2001
The role of cytokine polymorphisms in rejection after solid organ transplantation
SE Marshall, KI Welsh
Genes and Immunity 2001
Interleukin 6 gene promoter polymorphism is not associated with Kawasaki disease
MH Sohn, MW Hur, DS Kim
Genes and Immunity 2001
Interferon-γ and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation
J Cavet, AM Dickinson, J Norden, PR Taylor, GH Jackson, PG Middleton
Blood 2001
Real-Time PCR Assay with Fluorescent Hybridization Probes for Rapid Interleukin-6 Promoter (−174G→C) Genotyping
T Bertsch, W Zimmer, W Casarin, C Denz, M Quintel, K Fassbender
Clinical chemistry 2001
Inflammatory bowel disease is associated with a novel promoter polymorphism of natural resistance-associated macrophage protein 1 (NRAMP1) gene: NRAMP1 gene polymorphism
Y Kojima, Y Kinouchi, S Takahashi, K Negoro, N Hiwatashi, T Shimosegawa
Tissue Antigens 2001
Genetic determinants of IL-6 expression levels do not influence bone loss in inflammatory bowel disease
C Schulte, H Goebell, H D Röher, K M Schulte
Digestive Diseases and Sciences 2001
Candidate genes and confirmed genetic polymorphisms associated with cardiovascular diseases: a tabular assessment
Z Tang, R P Tracy
Journal of Thrombosis and Thrombolysis 2001
Use of biologics in the treatment of childhood rheumatic diseases
T Arkachaisri, TJ Lehman
Current Rheumatology Reports 2000
A Polymorphism in the Promoter Region of the Gene for Interleukin-6 Is Associated with Susceptibility to Type 1 Diabetes Mellitus
MM Jahromi, BA Millward, AG Demaine
Journal of Interferon & Cytokine Research 2000
Interleukin-6 Gene Polymorphism Is Related to Bone Mineral Density During and After Puberty in Healthy White Males: A Cross-Sectional and Longitudinal Study
M Lorentzon, R Lorentzon, P Nordström
Journal of Bone and Mineral Research 2000
Single nucleotide polymorphisms and the future of genetic epidemiology
NJ Schork, D Fallin, JS Lanchbury
Clinical Genetics 2000
Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?
JS Yudkin, M Kumari, SE Humphries, V Mohamed-Ali
Atherosclerosis 2000
Predictive value of interleukin 1 gene polymorphisms for surgery
A Crilly, N Maiden, HA Capell, R Madhok
Annals of the rheumatic diseases 2000
Interleukin-6 is an essential, corticotropin-releasing hormone-independent stimulator of the adrenal axis during immune system activation
KE Bethin, SK Vogt, LJ Muglia
Proceedings of the National Academy of Sciences 2000
Polymorphism in regulatory gene sequences
NA Mitchison
Genome biology 2000
The development and compensation of biliary cirrhosis in interleukin-6-deficient mice
T Ezure, T Sakamoto, H Tsuji, JG 3rd, N Murase, JJ Fung, AJ Demetris
The American Journal of Pathology 2000
No association of serum levels of interleukin-6 and its soluble receptor components with a genetic variation in the 3′flanking region of the interleukin-6 gene in patients with multiple sclerosis
S Schmidt
Neuroscience Letters 2000
Genetic polymorphisms in the cathespin D and interleukin-6 genes and the risk of Alzheimer's disease
TJ Bhojak, ST DeKosky, M Ganguli, MI Kamboh
Neuroscience Letters 2000
Association between an interleukin-6 promoter and 3′ flanking region haplotype and reduced Alzheimer's disease risk in a German population
M Bagli, A Papassotiropoulos, M Knapp, F Jessen, ML Rao, W Maier, R Heun
Neuroscience Letters 2000
Neonatal onset of rash in Still’s disease
PH Hoeger, N Veelken, I Foeldvari, M Kurtze, HD Foss
The Journal of Pediatrics 2000
El aumento de la actividad proinflamatoria es consustancial a la resistencia a la insulina
JM Fernández-Real, W Ricart
Medicina Clínica 2000
Stromelysin-1 and interleukin-6 gene promoter polymorphisms are determinants of asymptomatic carotid artery atherosclerosis
R Rauramaa, SB Väisänen, LA Luong, A Schmidt-Trücksäss, IM Penttilä, C Bouchard, J Töyry, SE Humphries
Arteriosclerosis, thrombosis, and vascular biology 2000
An IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in men infected with human immunodeficiency virus
CB Foster, T Lehrnbecher, S Samuels, S Stein, F Mol, JA Metcalf, K Wyvill, SM Steinberg, J Kovacs, A Blauvelt, R Yarchoan, SJ Chanock
Blood 2000
Variants of Trophic Factors and Expression of Cardiac Hypertrophy in Patients with Hypertrophic Cardiomyopathy
R Patel, DS Lim, D Reddy, SF Nagueh, S Lutucuta, MJ Sole, WA Zoghbi, MA Quiñones, R Roberts, AJ Marian
Journal of Molecular and Cellular Cardiology 2000
The Development and Compensation of Biliary Cirrhosis in Interleukin-6-Deficient Mice
T Ezure, T Sakamoto, H Tsuji, JG Lunz, N Murase, JJ Fung, AJ Demetris
The American Journal of Pathology 2000
Interleukin 6, tumour necrosis factor alpha, interleukin 1beta and interleukin 1 receptor antagonist promoter or coding gene polymorphisms in multiple myeloma
CY Zheng, DR Huang, S Bergenbrant, A Sundblad, A Osterborg, M Bjorkholm, G Holm, Q Yi
British Journal of Haematology 2000
Measurement of Cytokines in Clinical Samples Using Immunoassays: Problems and Pitfalls
RE Banks
Critical Reviews in Clinical Laboratory Sciences 2000
Cooperative Influence of Genetic Polymorphisms on Interleukin 6 Transcriptional Regulation
CF Terry, V Loukaci, FR Green
The Journal of biological chemistry 2000
THE IMPACT OF RECIPIENT CYTOKINE GENOTYPE ON ACUTE REJECTION AFTER RENAL TRANSPLANTATION:
SE Marshall, AJ McLaren, NA Haldar, M Bunce, PJ Morris, KI Welsh
Transplantation 2000
Cytokine Gene Polymorphisms in Autoimmune Thyroid Disease
PJ Hunt, SE Marshall, AP Weetman, JI Bell, JA Wass, KI Welsh
The Journal of clinical endocrinology and metabolism 2000
Type 1 and type 2 immune responses in children: their relevance in juvenile arthritis
LR Wedderburn, P Woo
Springer Seminars in Immunopathology 1999
New developments in IL-6 dependent biology and therapy: where do we stand and what are the options?
KJ Kallen, PR Galle, S Rose-John
Expert Opinion on Investigational Drugs 1999
The genetics of rheumatoid arthritis: Influences on susceptibility, severity, and treatment response
SL Bridges
Current Rheumatology Reports 1999
Polymorphic haplotypes of the interleukin-10 5? flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis
E Crawley, R Kay, J Sillibourne, P Patel, I Hutchinson, P Woo
Arthritis & Rheumatism 1999
Biologic therapies in rheumatoid arthritis
KJ Bulpitt
Current Rheumatology Reports 1999
Mining variations in genes of innate and phagocytic immunity: current status and future prospects
C B Foster, S J Chanock
Current Opinion in Hematology 1999
Cytokines in children with arthritis
E Crawley, P Woo
Clinical Immunology Newsletter 1998
Rheumatology
RA Asherson, R Cervera, DP D'Cruz, GR Hughes
Postgraduate medical journal 1991
Juvenile Idiopathic Arthritis-related Uveitis:
MR Kesen, V Setlur, DA Goldstein
International Ophthalmology Clinics
Septic Shock and Respiratory Failure in Community-acquired Pneumonia Have Different TNF Polymorphism Associations
GW Waterer, MW Quasney, RM Cantor, RG Wunderink
American journal of respiratory and critical care medicine 2001
Cytokine genotypes in kidney, heart, and lung recipients: consequences for acute and chronic rejection
A Jackson, S Palmer, RD Davis, A Pappendick, E Pearson, K Savik, S Ormaza, M Hertz, M Dacey, L Miller, NL Reinsmoen
Transplantation Proceedings 2001
TNF-α and IL-6 gene polymorphism and rejection in kidney transplantation recipients
D Reviron, B Dussol, M Andre, P Brunet, P Mercier, Y Berland
Transplantation Proceedings 2001
Cytokine Polymorphisms in Systemic Lupus Erythematosus and Sjogren's Syndrome
V Magnusson, B Nakken, AI Bolstad, ME Alarcon-Riquelme
Scandinavian Journal of Immunology 2001
IL-6 POLYMORPHISM, ANTI-IL-6 THERAPY AND ANIMAL MODELS OF MULTIPLE MYELOMA
R Jeffery, NA Mitchison
Cytokine 2001
A functional polymorphic variant in the interleukin-6 gene promoter associated with low bone resorption in postmenopausal women
SL Ferrari, P Garnero, S Emond, H Montgomery, SE Humphries, SL Greenspan
Arthritis & Rheumatism 2001
Detection of the single-base substitution ?174 G?C in the interleukin-6 gene by real-time polymerase chain reaction: Comment on the article by Moos et al
N Helmy, FE Maly, L Bestmann
Arthritis & Rheumatism 2001
Inflamm-aging: An Evolutionary Perspective on Immunosenescence
C Franceschi, M Bonafè, S Valensin, F Olivieri, MD Luca, E Ottaviani, GD Benedictis
Annals of the New York Academy of Sciences 2000
Identification and efficient genotyping of an (A)n/(T)m polymorphism within the 5' untranslated region of the human IL6 gene
F Tschentscher, A Kalt, V Hoffmann, J Epplen, C Hardt
European Journal of Immunogenetics 2000
Allelic selection of human IL-2 gene
F Matesanz, C Delgado, M Fresno, A Alcina
European Journal of Immunology 2000
Polymorphisms at −174 and in the 3′ flanking region of interleukin-6 (IL-6) gene in patients with myasthenia gravis
DR Huang, C Zheng, R Giscombe, G Matell, R Pirskanen, AK Lefvert
Journal of Neuroimmunology 1999
Polymorphism of the human TNF-α promoter — random variation or functional diversity?
RD Allen
Molecular Immunology 1999
Plasma IL-8 and IL-6 levels can be used to define a group with low risk of septicaemia among cancer patients with fever and neutropenia
ES de Bont, E Vellenga, JC Swaanenburg, V Fidler, PJ Brummen, WA Kamps
British Journal of Haematology 1999
Preterm birth and single nucleotide polymorphisms in cytokine genes
Qin Zhu, Jian Sun, Ying Chen
Translational Pediatrics
DAMAGE CONTROL ORTHOPAEDICS: EVOLVING CONCEPTS IN THE TREATMENT OF PATIENTS WHO HAVE SUSTAINED ORTHOPAEDIC TRAUMA
CS Roberts, HC Pape, AL Jones, AL Malkani, JL Rodriguez, PV Giannoudis
The Journal of Bone and Joint Surgery. American volume. 2005
Genetic Polymorphisms Associated With Susceptibility and Outcome in ARDS
RP Marshall, S Webb, MR Hill, SE Humphries, GJ Laurent
Chest 2002
Juvenile rheumatoid arthritis as a complex genetic trait
DN Glass, EH Giannini
Arthritis & Rheumatism 1999
Measuring Plasma Fibrinogen to Predict Stroke and Myocardial Infarction: An Update
G Maresca, AD Blasio, R Marchioli, GD Minno
Arteriosclerosis, thrombosis, and vascular biology 1999
Critical Care Nephrology
C Ronco, R Bellomo
1998
Pancreatic Disease
EC Kafka, MH Kalser
Postgraduate Medicine 1975

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