Finding NEMO: genetic disorders of NF-κB activation
Jordan S. Orange, Raif S. Geha
Jordan S. Orange, Raif S. Geha
Published October 1, 2003
Citation Information: J Clin Invest. 2003;112(7):983-985. https://doi.org/10.1172/JCI19960.
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Commentary

Finding NEMO: genetic disorders of NF-κB activation

Abstract

The pathways between a receptor and transcriptional activation mediated by NF-κB are complex. The study of human gene mutations that result in dysregulation of these pathways has provided insight into the functions of individual components of the pathway, their interrelations, and the significance of these systems to the organism .

Authors

Jordan S. Orange, Raif S. Geha

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Genetic disorders of NF-κB activation in humans

Genetic disorders of NF-κB activation in humans