Functionally mature virus-specific CD8+ T memory cells in congenitally infected newborns: proof of principle for neonatal vaccination?
P.G. Holt
P.G. Holt
Published June 1, 2003
Citation Information: J Clin Invest. 2003;111(11):1645-1647. https://doi.org/10.1172/JCI18805.
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Commentary

Functionally mature virus-specific CD8+ T memory cells in congenitally infected newborns: proof of principle for neonatal vaccination?

Abstract

The presence in newborns of a mature and functional CD8+ T cell response to congenital cytomegalovirus infection suggests that the machinery necessary to prime such responses is present in utero and raises questions related to neonatal vaccination.

Authors

P.G. Holt

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Figure 1

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The central role of CD4+ T cell “help” in the development of acquired re...
The central role of CD4+ T cell “help” in the development of acquired resistance to pathogens.