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Abstract
Authors
Hossein Ardehali
Figure 1
Mechanism of GLP-1 production and its beneficial effects.
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Proglucagon is released from intestinal cells and is processed into its components, one of which is GLP-1. GLP-1 binds to its receptor in pancreas and leads to insulin secretion. GLP-1 exerts additional beneficial effects by binding to the GLP-1 receptor in other tissues or via indirectly reducing inflammation. The list of FDA-approved GLP-1RA drugs is also included in the figure.
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