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ResearchIn-Press PreviewGastroenterologyTherapeutics
Open Access | 
10.1172/JCI182217
MOGAT3-Mediated DAG Accumulation Drives Acquired Resistance to Anti-BRAF/EGFR Therapy in BRAFV600E-Mutant Metastatic Colorectal Cancer
Jiawei Wang,1 Huogang Wang,1 Wei Zhou,1 Xin Luo,1 Huijuan Wang,1 Qing Meng,1 Jiaxin Chen,1 Xiaoyu Chen,1 Yinqiang Liu,1 David W. Chan,2 Zhenyu Ju,3 and Zhangfa Song1
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Wang, J. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Wang, H. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Zhou, W. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Luo, X. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Wang, H. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Meng, Q. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Chen, J. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Chen, X. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Liu, Y. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Chan, D. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Ju, Z. in: JCI | PubMed | Google Scholar
1Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Hangzhou, China
2School of Medicine, The Chinese University of Hong Kong, Shenzhen, China
3Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
Find articles by Song, Z. in: JCI | PubMed | Google Scholar
Published October 22, 2024 - More info
Copyright © 2024, Wang et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Copyright © 2024 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)