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ResearchIn-Press PreviewHematologyOncology
Open Access | 
10.1172/JCI181659
ATM-dependent DNA damage response constrains cell growth and drives clonal hematopoiesis in telomere biology disorders
Christopher M. Sande,1 Stone Chen,2 Dana V. Mitchell,3 Ping Lin,2 Diana M. Abraham,2 Jessie M. Cheng,2 Talia Gebhard,2 Rujul J. Deolikar,2 Colby Freeman,2 Mary Zhou,2 Sushant Kumar,2 Michael Bowman,4 Robert L. Bowman,4 Shannon Zheng,2 Bolormaa Munkhbileg,2 Qijun Chen,5 Natasha L. Stanley,2 Kathy Guo,2 Ajibike Lapite,6 Ryan Hausler,2 Deanne M. Taylor,3 James Corines,5 Jennifer J.D. Morrissette,5 David B. Lieberman,5 Guang Yang,5 Olga Shestova,2 Saar Gill,2 Jiayin Zheng,7 Kelcy Smith-Simmer,8 Lauren G. Banaszak,8 Kyle N. Shoger,8 Erica F. Reinig,9 Madilynn Peterson,8 Peter Nicholas,10 Amanda J. Walne,11 Inderjeet Dokal,11 Justin P. Rosenheck,12 Karolyn A. Oetjen,13 Daniel C. Link,14 Andrew E. Gelman,14 Christopher R. Reilly,15 Ritika Dutta,15 R. Coleman Lindsley,15 Karyn J. Brundige,16 Suneet Agarwal,16 Alison A. Bertuch,6 Jane E. Churpek,8 Laneshia K. Tague,17 F. Brad Johnson,5 Timothy S. Olson,10 and Daria V. Babushok2
1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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Oetjen, K.
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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Gelman, A.
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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Lindsley, R.
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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Bertuch, A.
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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Tague, L.
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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1Department of Laboratories, Seattle Children's Hospital, Seattle, United States of America
2Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, United States of America
4Department of Cancer Biology, University of Pennsylvania, Philadelphia, United States of America
5Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, United States of America
6Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, United States of America
7Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America
8Division of Hematology, Medical Oncology, and Palliative Care, Department o, University of Wisconsin-Madison, Madison, United States of America
9Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, United States of America
10Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, United States of America
11Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
12Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Departmen, The Ohio State University, Columbus, United States of America
13Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University School of Medicine, St. Louis, United States of America
14Division of Oncology, Section of Stem Cell Biology, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
15Division of Hematological Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America
16Division of Hematology/Oncology, Boston Children's Hospital, Boston, United States of America
17Division of Pulmonary & Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
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Published April 3, 2025 - More info
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