The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell–mediated responses
Lawrence Y. Lee, … , Damien McDevitt, Eric L. Brown
Lawrence Y. Lee, … , Damien McDevitt, Eric L. Brown
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1461-1471. https://doi.org/10.1172/JCI16318.
View: Text | PDF
Article Infectious disease

The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell–mediated responses

Abstract

Research Article

Authors

Lawrence Y. Lee, Yuko J. Miyamoto, Bradley W. McIntyre, Magnus Höök, Kirk W. McCrea, Damien McDevitt, Eric L. Brown

×

Figure 5

Options: View larger image (or click on image) Download as PowerPoint
Recombinant Map19-mediated inhibition of DTH. DbpA-immunized mice were t...
Recombinant Map19-mediated inhibition of DTH. DbpA-immunized mice were treated with recombinant Map19 on the day of immunization (day 0) and on days 2, 4, and 6 after immunization. On day 7, mice were challenged with DbpA and footpads were measured 0 and 24 hours after challenge. Mice treated with recombinant Map19 had a significantly reduced DTH response compared with immunized and challenged mice (*P < 0.0001; Student t test). Data are expressed as the mean ± SE of five mice.