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Androgen receptor–mediated inhibition of cutaneous wound healing
Gillian S. Ashcroft, Stuart J. Mills
Gillian S. Ashcroft, Stuart J. Mills
Published September 1, 2002
Citation Information: J Clin Invest. 2002;110(5):615-624. https://doi.org/10.1172/JCI15704.
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Androgen receptor–mediated inhibition of cutaneous wound healing

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Abstract

Research Article

Authors

Gillian S. Ashcroft, Stuart J. Mills

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Figure 3

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Increased hair follicle proliferation following gonadectomy does not con...
Increased hair follicle proliferation following gonadectomy does not contribute to the wound healing response. (a) Day 3 macroscopic and histological wounds from intact wild-type and intact null (hr/hr) mice showed no differences in healing. By contrast, castrated hr/hr and castrated wild-type mice healed significantly more quickly. Magnification: ×10. (b) Quantification of wound areas at day 3 illustrated a significant decrease in area (accelerated healing) in the castrated hr/hr null (KO) animals compared with the intact hr/hr littermates, and wild-type (WT) castrated compared with wild-type intact. n = 6 per group; *P < 0.05.

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