Hiroshi Yamamoto, Charlotte E. Lee, Jacob N. Marcus, Todd D. Williams, J. Michael Overton, Marisol E. Lopez, Anthony N. Hollenberg, Laurie Baggio, Clifford B. Saper, Daniel J. Drucker, Joel K. Elmquist
Intracerebroventricular EXN-4 activates TH transcription in the medullary catecholamine neurons. All sections were hybridized with a specific TH intronic RNA probe 15 minutes after administration of i.c.v. EXN-4 (left column) or PFS (right column) in several brainstem regions, including (a and b) the LC, (c and d) the A5, (e and f) the RVLM, (g and h) the CVLM, and (i and j) the caudal part of the NTS. CC, central canal. Scale bar = 100 μm.